Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP24_F_M03
(895 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ277724-1|CAB90213.1| 377|Homo sapiens histone deacetylase 8 p... 235 1e-61
AF230097-1|AAF73076.1| 377|Homo sapiens class I histone deacety... 235 1e-61
AF245664-1|AAF73428.1| 377|Homo sapiens histone deacetylase 8 p... 234 3e-61
BC050433-1|AAH50433.1| 377|Homo sapiens histone deacetylase 8 p... 233 8e-61
U50079-1|AAC50475.1| 482|Homo sapiens histone deacetylase HD1 p... 190 6e-48
D50405-1|BAA08909.1| 482|Homo sapiens RPD3 protein protein. 190 6e-48
CR541717-1|CAG46518.1| 482|Homo sapiens HDAC1 protein. 190 6e-48
BC000301-1|AAH00301.1| 482|Homo sapiens histone deacetylase 1 p... 190 6e-48
AY627042-1|AAT44863.1| 482|Homo sapiens histone deacetylase 1 p... 190 6e-48
AL109945-2|CAI22886.1| 482|Homo sapiens histone deacetylase 1 p... 190 6e-48
BC031055-1|AAH31055.2| 571|Homo sapiens HDAC2 protein protein. 189 1e-47
AL671967-1|CAI15363.1| 488|Homo sapiens histone deacetylase 2 p... 189 1e-47
AL590398-2|CAI14207.1| 488|Homo sapiens histone deacetylase 2 p... 189 1e-47
U31814-1|AAC50814.1| 488|Homo sapiens transcriptional regulator... 186 7e-47
U75697-1|AAB88241.1| 428|Homo sapiens RPD3-2B protein. 176 8e-44
U75696-1|AAB88240.1| 429|Homo sapiens RPD3-2A protein. 176 8e-44
U66914-1|AAC52038.1| 428|Homo sapiens histone deacetylase 3 pro... 176 8e-44
BC000614-1|AAH00614.1| 428|Homo sapiens histone deacetylase 3 p... 176 8e-44
AF059650-1|AAC26509.1| 428|Homo sapiens histone deacetylase 3 p... 176 8e-44
AF039703-1|AAC98927.1| 428|Homo sapiens histone deacetylase 3 p... 176 8e-44
AF005482-1|AAB87752.1| 371|Homo sapiens histone deacetylase-3C ... 157 7e-38
AL109945-1|CAI22885.1| 211|Homo sapiens histone deacetylase 1 p... 145 2e-34
AF053138-1|AAC08351.1| 259|Homo sapiens histone deacetylase 3 p... 138 2e-32
AF212246-1|AAK14930.1| 163|Homo sapiens CDA07 protein. 123 8e-28
AL590398-1|CAI14206.1| 158|Homo sapiens histone deacetylase 2 p... 114 4e-25
BT009771-1|AAP88773.1| 614|Homo sapiens histone deacetylase 7A ... 99 2e-20
BC064840-1|AAH64840.1| 954|Homo sapiens HDAC7A protein protein. 99 2e-20
BC020505-1|AAH20505.2| 711|Homo sapiens HDAC7A protein protein. 99 2e-20
AY321367-1|AAP84704.1| 915|Homo sapiens histone deacetylase 7A ... 99 2e-20
AY302468-1|AAQ18232.1| 991|Homo sapiens histone deacetylase pro... 99 2e-20
AL117455-1|CAB55935.1| 878|Homo sapiens hypothetical protein pr... 99 2e-20
AK001190-1|BAA91545.1| 614|Homo sapiens protein ( Homo sapiens ... 98 3e-20
AK024469-1|BAB15759.1| 484|Homo sapiens FLJ00062 protein protein. 97 1e-19
AF239243-1|AAF63491.1| 855|Homo sapiens histone deacetylase 7 p... 96 1e-19
BC111735-1|AAI11736.1| 1024|Homo sapiens HDAC9 protein protein. 95 4e-19
AY197371-1|AAO27363.1| 1069|Homo sapiens histone deacetylase 9 p... 95 4e-19
AY032737-1|AAK66821.1| 1011|Homo sapiens histone deacetylase 9 p... 95 4e-19
AJ459808-1|CAD30851.1| 1066|Homo sapiens histone decetylase 9b p... 95 4e-19
BC039904-1|AAH39904.1| 972|Homo sapiens HDAC4 protein protein. 91 5e-18
AK122588-1|BAC56929.1| 308|Homo sapiens FLJ00413 protein protein. 91 5e-18
AF132607-1|AAD29046.1| 1084|Homo sapiens histone deacetylase 4 p... 91 5e-18
AC017028-1|AAX93070.1| 1052|Homo sapiens unknown protein. 91 5e-18
AB006626-1|BAA22957.2| 1097|Homo sapiens KIAA0288 protein protein. 91 5e-18
AK095820-1|BAC04630.1| 314|Homo sapiens protein ( Homo sapiens ... 90 1e-17
AC002410-1|AAS07401.1| 156|Homo sapiens unknown protein. 90 1e-17
BC051824-1|AAH51824.1| 1122|Homo sapiens histone deacetylase 5 p... 89 2e-17
AF132608-1|AAD29047.1| 1122|Homo sapiens histone deacetylase 5 p... 89 2e-17
AF039691-1|AAC18040.1| 897|Homo sapiens antigen NY-CO-9 protein. 89 2e-17
AB177853-1|BAD66831.1| 716|Homo sapiens KIAA0600 splice variant... 89 2e-17
AB011172-1|BAA25526.2| 1080|Homo sapiens KIAA0600 protein protein. 87 8e-17
BC006453-1|AAH06453.1| 276|Homo sapiens HDAC7A protein protein. 82 2e-15
AK001032-1|BAA91474.1| 276|Homo sapiens protein ( Homo sapiens ... 82 2e-15
BC069243-1|AAH69243.1| 1215|Homo sapiens HDAC6 protein protein. 82 3e-15
BC013737-1|AAH13737.1| 1063|Homo sapiens HDAC6 protein protein. 82 3e-15
AJ011972-1|CAA09893.1| 1215|Homo sapiens histone deacetylase-lik... 82 3e-15
AF174499-1|AAF36540.1| 1066|Homo sapiens GR AF-1 specific histon... 82 3e-15
AF132609-1|AAD29048.1| 1215|Homo sapiens histone deacetylase 6 p... 82 3e-15
AB020708-1|BAA74924.2| 1233|Homo sapiens KIAA0901 protein protein. 82 3e-15
AK127118-1|BAC86838.1| 632|Homo sapiens protein ( Homo sapiens ... 81 7e-15
AY032738-1|AAK66822.1| 879|Homo sapiens histone deacetylase 9a ... 80 1e-14
AC002410-2|AAS07402.1| 144|Homo sapiens unknown protein. 75 3e-13
CR456465-1|CAG30351.1| 669|Homo sapiens dJ402G11.7 protein. 73 2e-12
BC125083-1|AAI25084.1| 669|Homo sapiens histone deacetylase 10 ... 73 2e-12
AL022328-11|CAB63048.1| 673|Homo sapiens protein ( Human DNA se... 73 2e-12
AF426160-1|AAL30513.1| 669|Homo sapiens histone deacetylase 10 ... 73 2e-12
AF407273-1|AAK92206.1| 649|Homo sapiens histone deacetylase 10 ... 73 2e-12
AF407272-1|AAK92205.1| 669|Homo sapiens histone deacetylase 10 ... 73 2e-12
AF393962-1|AAK84023.1| 669|Homo sapiens histone deacetylase 10 ... 73 2e-12
AY450395-1|AAS48345.1| 396|Homo sapiens histone deacetylase 10 ... 72 3e-12
BC009676-1|AAH09676.1| 347|Homo sapiens histone deacetylase 11 ... 61 6e-09
AK025890-1|BAB15272.1| 347|Homo sapiens protein ( Homo sapiens ... 61 6e-09
CR457341-1|CAG33622.1| 225|Homo sapiens HDAC11 protein. 53 2e-06
AK025426-1|BAB15127.1| 225|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK027734-1|BAB55329.1| 191|Homo sapiens protein ( Homo sapiens ... 33 1.4
AY034072-1|AAK56405.1| 2713|Homo sapiens chromodomain helicase D... 31 7.5
AL121674-2|CAI21744.1| 2715|Homo sapiens chromodomain helicase D... 31 7.5
AL031669-3|CAI22255.1| 2715|Homo sapiens chromodomain helicase D... 31 7.5
AL031667-8|CAI42983.1| 524|Homo sapiens chromodomain helicase D... 31 7.5
AL031667-2|CAI42977.1| 2715|Homo sapiens chromodomain helicase D... 31 7.5
AK026022-1|BAB15325.1| 757|Homo sapiens protein ( Homo sapiens ... 31 7.5
AF525085-1|AAN59903.1| 488|Homo sapiens RIGB protein. 31 7.5
AB037756-1|BAA92573.2| 2041|Homo sapiens KIAA1335 protein protein. 31 7.5
>AJ277724-1|CAB90213.1| 377|Homo sapiens histone deacetylase 8
protein.
Length = 377
Score = 235 bits (576), Expect = 1e-61
Identities = 99/216 (45%), Positives = 145/216 (67%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C L + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSV 774
NW GGWHHA + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+GV+DA+ T V
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKV 195
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T+S HKF PGF+PGTG + D+G G G YS N P+
Sbjct: 196 MTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPI 231
>AF230097-1|AAF73076.1| 377|Homo sapiens class I histone
deacetylase protein.
Length = 377
Score = 235 bits (576), Expect = 1e-61
Identities = 99/216 (45%), Positives = 145/216 (67%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C L + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSV 774
NW GGWHHA + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+GV+DA+ T V
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKV 195
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T+S HKF PGF+PGTG + D+G G G YS N P+
Sbjct: 196 MTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPI 231
>AF245664-1|AAF73428.1| 377|Homo sapiens histone deacetylase 8
protein.
Length = 377
Score = 234 bits (573), Expect = 3e-61
Identities = 99/216 (45%), Positives = 145/216 (67%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C L + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSV 774
NW GGWHHA + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+GV+DA+ T V
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKV 195
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T+S HKF PGF+PGTG + D+G G G YS N P+
Sbjct: 196 MTVSLHKFSPGFFPGTGDVSDVGLGKGWYYSVNVPI 231
>BC050433-1|AAH50433.1| 377|Homo sapiens histone deacetylase 8
protein.
Length = 377
Score = 233 bits (569), Expect = 8e-61
Identities = 98/216 (45%), Positives = 144/216 (66%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSPAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSV 774
NW GGWHHA + A GFCY+ND V+ I +L+ KF+ ILYVDLD+HHG+GV+DA+ T V
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKV 195
Query: 775 YTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
T+S HKF PGF+PGTG + D+G G G YS N P+
Sbjct: 196 MTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPI 231
>U50079-1|AAC50475.1| 482|Homo sapiens histone deacetylase HD1
protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>D50405-1|BAA08909.1| 482|Homo sapiens RPD3 protein protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>CR541717-1|CAG46518.1| 482|Homo sapiens HDAC1 protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>BC000301-1|AAH00301.1| 482|Homo sapiens histone deacetylase 1
protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>AY627042-1|AAT44863.1| 482|Homo sapiens histone deacetylase 1
protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>AL109945-2|CAI22886.1| 482|Homo sapiens histone deacetylase 1
protein.
Length = 482
Score = 190 bits (463), Expect = 6e-48
Identities = 87/197 (44%), Positives = 127/197 (64%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRP-DNMSEYSKQMQ 92
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV +A L DIA+NW GG HHA + A GFCY
Sbjct: 93 RFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCY 152
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 153 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 211
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 212 RDIGAGKGKYYAVNYPL 228
>BC031055-1|AAH31055.2| 571|Homo sapiens HDAC2 protein protein.
Length = 571
Score = 189 bits (461), Expect = 1e-47
Identities = 86/197 (43%), Positives = 126/197 (63%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 118 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMQ 176
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA + A GFCY
Sbjct: 177 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCY 236
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 237 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 295
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ NFP+
Sbjct: 296 RDIGAGKGKYYAVNFPM 312
>AL671967-1|CAI15363.1| 488|Homo sapiens histone deacetylase 2
protein.
Length = 488
Score = 189 bits (461), Expect = 1e-47
Identities = 86/197 (43%), Positives = 126/197 (63%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 35 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMQ 93
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA + A GFCY
Sbjct: 94 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCY 153
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 154 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 212
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ NFP+
Sbjct: 213 RDIGAGKGKYYAVNFPM 229
>AL590398-2|CAI14207.1| 488|Homo sapiens histone deacetylase 2
protein.
Length = 488
Score = 189 bits (461), Expect = 1e-47
Identities = 86/197 (43%), Positives = 126/197 (63%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 35 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMQ 93
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA + A GFCY
Sbjct: 94 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCY 153
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 154 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 212
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ NFP+
Sbjct: 213 RDIGAGKGKYYAVNFPM 229
>U31814-1|AAC50814.1| 488|Homo sapiens transcriptional regulator
homolog RPD3 protein.
Length = 488
Score = 186 bits (454), Expect = 7e-47
Identities = 86/197 (43%), Positives = 124/197 (62%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q
Sbjct: 35 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMH 93
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA A GFCY
Sbjct: 94 IFNVGEDCPAFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKYEASGFCY 153
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 154 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 212
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ NFP+
Sbjct: 213 RDIGAGKGKYYAVNFPM 229
>U75697-1|AAB88241.1| 428|Homo sapiens RPD3-2B protein.
Length = 428
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>U75696-1|AAB88240.1| 429|Homo sapiens RPD3-2A protein.
Length = 429
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 29 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 88
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 89 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 147
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 148 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 207
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 208 YEVGAESGRYYCLNVPL 224
>U66914-1|AAC52038.1| 428|Homo sapiens histone deacetylase 3
protein.
Length = 428
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>BC000614-1|AAH00614.1| 428|Homo sapiens histone deacetylase 3
protein.
Length = 428
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>AF059650-1|AAC26509.1| 428|Homo sapiens histone deacetylase 3
protein.
Length = 428
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>AF039703-1|AAC98927.1| 428|Homo sapiens histone deacetylase 3
protein.
Length = 428
Score = 176 bits (429), Expect = 8e-44
Identities = 84/197 (42%), Positives = 118/197 (59%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R L H+L+ YGL K+ V + AS D+ FHS+ Y++ L++++ + + + +
Sbjct: 28 RLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNA 87
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP P +FE S G S+ A L I DIAINW GG HHA A GFCY
Sbjct: 88 -FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCY 146
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIVI I +L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG +
Sbjct: 147 VNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDM 206
Query: 832 EDIGCGDGEGYSCNFPL 882
++G G Y N PL
Sbjct: 207 YEVGAESGRYYCLNVPL 223
>AF005482-1|AAB87752.1| 371|Homo sapiens histone deacetylase-3C
protein.
Length = 371
Score = 157 bits (380), Expect = 7e-38
Identities = 72/164 (43%), Positives = 101/164 (61%)
Frame = +1
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
FHS+ Y++ L++++ + + + + F +G DCP P +FE S G S+ A L
Sbjct: 4 FHSEDYIDFLQRVSPTNMQGFTKSLNA-FNVGDDCPVFPGLFEFCSRYTGASLQGATQLN 62
Query: 571 MGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQD 750
I DIAINW GG HHA A GFCYVNDIVI I +L +LY+D+D+HHG+GVQ+
Sbjct: 63 NKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQE 122
Query: 751 AYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDGEGYSCNFPL 882
A++ T V T+SFHK+ F+PGTG + ++G G Y N PL
Sbjct: 123 AFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPL 166
>AL109945-1|CAI22885.1| 211|Homo sapiens histone deacetylase 1
protein.
Length = 211
Score = 145 bits (351), Expect = 2e-34
Identities = 80/197 (40%), Positives = 115/197 (58%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D
Sbjct: 34 RIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRS---IRPD-------- 82
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
NM E + S A K L DIA+NW GG HHA + A GFCY
Sbjct: 83 ------------NMSEYSKQMQRSS--AVK-LNKQQTDIAVNWAGGLHHAKKSEASGFCY 127
Query: 652 VNDIVIAIEKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSI 831
VNDIV+AI +L + +LY+D+D+HHG+GV++A++TT V T+SFHK+ ++PGTG +
Sbjct: 128 VNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDL 186
Query: 832 EDIGCGDGEGYSCNFPL 882
DIG G G+ Y+ N+PL
Sbjct: 187 RDIGAGKGKYYAVNYPL 203
>AF053138-1|AAC08351.1| 259|Homo sapiens histone deacetylase 3
protein.
Length = 259
Score = 138 bits (335), Expect = 2e-32
Identities = 63/129 (48%), Positives = 80/129 (62%)
Frame = +1
Query: 496 PPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI 675
P P +FE S G S+ A L I DIAINW GG HHA A GFCYVNDIVI I
Sbjct: 1 PVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGI 60
Query: 676 EKLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPGTGSIEDIGCGDG 855
+L +LY+D+D+HHG+GVQ+A++ T V T+SFHK+ F+PGTG + ++G G
Sbjct: 61 LELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESG 120
Query: 856 EGYSCNFPL 882
Y N PL
Sbjct: 121 RYYCLNVPL 129
>AF212246-1|AAK14930.1| 163|Homo sapiens CDA07 protein.
Length = 163
Score = 123 bits (297), Expect = 8e-28
Identities = 51/129 (39%), Positives = 82/129 (63%)
Frame = +1
Query: 235 YLWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLE 414
Y++ + V C L + RA +VH+LIEAY L ++++++ AS E++ FH+D YL+
Sbjct: 18 YIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQ 77
Query: 415 HLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAI 594
HL++++ DD + +G+GYDCP +F+ + I G ++TAA+CL G+ +AI
Sbjct: 78 HLQKVSQEGDD--DHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135
Query: 595 NWCGGWHHA 621
NW GGWHHA
Sbjct: 136 NWSGGWHHA 144
>AL590398-1|CAI14206.1| 158|Homo sapiens histone deacetylase 2
protein.
Length = 158
Score = 114 bits (275), Expect = 4e-25
Identities = 57/138 (41%), Positives = 81/138 (58%)
Frame = +1
Query: 292 RARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDE 471
R R+ HNL+ YGL K+++ R A+ E++ +HSD Y++ L+ I D+ + Q +
Sbjct: 22 RIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRP-DNMSEYSKQMQ 80
Query: 472 NFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFCY 651
F +G DCP +FE GGSV A L D+A+NW GG HHA + A GFCY
Sbjct: 81 RFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCY 140
Query: 652 VNDIVIAIEKLKGKFKNI 705
VNDIV+AI +L K+ N+
Sbjct: 141 VNDIVLAILELL-KYVNL 157
>BT009771-1|AAP88773.1| 614|Homo sapiens histone deacetylase 7A
protein.
Length = 614
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 202 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 261
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 262 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 321
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 322 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 380
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 381 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 420
>BC064840-1|AAH64840.1| 954|Homo sapiens HDAC7A protein protein.
Length = 954
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 542 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 601
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 602 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 661
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 662 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 720
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 721 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 760
>BC020505-1|AAH20505.2| 711|Homo sapiens HDAC7A protein protein.
Length = 711
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 299 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 358
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 359 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 418
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 419 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 477
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 478 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 517
>AY321367-1|AAP84704.1| 915|Homo sapiens histone deacetylase 7A
variant 3 protein.
Length = 915
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 503 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 562
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 563 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 622
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 623 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 681
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 682 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 721
>AY302468-1|AAQ18232.1| 991|Homo sapiens histone deacetylase protein.
Length = 991
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 579 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 638
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 639 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 698
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 699 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 757
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 758 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 797
>AL117455-1|CAB55935.1| 878|Homo sapiens hypothetical protein
protein.
Length = 878
Score = 98.7 bits (235), Expect = 2e-20
Identities = 69/220 (31%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 466 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 525
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 526 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 585
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 586 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 644
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 645 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 684
>AK001190-1|BAA91545.1| 614|Homo sapiens protein ( Homo sapiens
cDNA FLJ10328 fis, clone NT2RM2000588, weakly similar to
HISTONE DEACETYLASE HDA1. ).
Length = 614
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/220 (30%), Positives = 112/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL+S+ + +R AS E+L HS+ LY + +
Sbjct: 202 RHPEHAGRIQSIWSRLQERGLLSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 261
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 262 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 321
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 322 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 380
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G GEG++ N
Sbjct: 381 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGASSGEGFNVN 420
>AK024469-1|BAB15759.1| 484|Homo sapiens FLJ00062 protein protein.
Length = 484
Score = 96.7 bits (230), Expect = 1e-19
Identities = 68/220 (30%), Positives = 111/220 (50%), Gaps = 19/220 (8%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 72 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 131
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A G VT A K + + +
Sbjct: 132 DNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGRVTDLAFKVASRELKN 191
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAY 756
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q +
Sbjct: 192 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 250
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
+ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 251 YQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 290
>AF239243-1|AAF63491.1| 855|Homo sapiens histone deacetylase 7
protein.
Length = 855
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/223 (30%), Positives = 112/223 (50%), Gaps = 22/223 (9%)
Frame = +1
Query: 271 RLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDI 438
R P GR + + + ++ GL S+ + +R AS E+L HS+ LY + +
Sbjct: 500 RHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKL 559
Query: 439 DDDYISNAQDENF-------GIGYDCPPVPNMFELVSTI--AGGSVT--AAKCLTMGIAD 585
D+ ++ + G+G D + N + A GSVT A K + + +
Sbjct: 560 DNGKLAGLLAQRMFEMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKN 619
Query: 586 -IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLK-----GKFKNILYVDLDVHHGNGVQ 747
A+ G HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q
Sbjct: 620 GFAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKASKILIVDWDVHHGNGTQ 678
Query: 748 DAYWTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
++ SV +S H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 679 QTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 721
>BC111735-1|AAI11736.1| 1024|Homo sapiens HDAC9 protein protein.
Length = 1024
Score = 94.7 bits (225), Expect = 4e-19
Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL++K + I+ AS E++ + HS+ LY + +D
Sbjct: 613 PEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDP 672
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIAD-I 588
+ + F G+G D + N + +A G V A+K + + +
Sbjct: 673 RILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGF 732
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++
Sbjct: 733 AVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYA 791
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
S+ +S H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 792 DPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 829
>AY197371-1|AAO27363.1| 1069|Homo sapiens histone deacetylase 9
protein.
Length = 1069
Score = 94.7 bits (225), Expect = 4e-19
Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL++K + I+ AS E++ + HS+ LY + +D
Sbjct: 658 PEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDP 717
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIAD-I 588
+ + F G+G D + N + +A G V A+K + + +
Sbjct: 718 RILLGDDSQKFFSSLPCGGLGVDSDTIWNELRSSGAARMAVGCVIELASKVASGELKNGF 777
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++
Sbjct: 778 AVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYA 836
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
S+ +S H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 837 DPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 874
>AY032737-1|AAK66821.1| 1011|Homo sapiens histone deacetylase 9
protein.
Length = 1011
Score = 94.7 bits (225), Expect = 4e-19
Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL++K + I+ AS E++ + HS+ LY + +D
Sbjct: 655 PEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDP 714
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIAD-I 588
+ + F G+G D + N + +A G V A+K + + +
Sbjct: 715 RILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGF 774
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++
Sbjct: 775 AVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYA 833
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
S+ +S H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 834 DPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 871
>AJ459808-1|CAD30851.1| 1066|Homo sapiens histone decetylase 9b
protein.
Length = 1066
Score = 94.7 bits (225), Expect = 4e-19
Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL++K + I+ AS E++ + HS+ LY + +D
Sbjct: 655 PEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDP 714
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIAD-I 588
+ + F G+G D + N + +A G V A+K + + +
Sbjct: 715 RILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGF 774
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++
Sbjct: 775 AVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYA 833
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
S+ +S H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 834 DPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 871
>BC039904-1|AAH39904.1| 972|Homo sapiens HDAC4 protein protein.
Length = 972
Score = 91.1 bits (216), Expect = 5e-18
Identities = 66/220 (30%), Positives = 108/220 (49%), Gaps = 21/220 (9%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL K + IR A+ E+L HS+ LY + +D
Sbjct: 564 PEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDS 623
Query: 445 DYISNAQDENF------GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC- 603
+ + F G+G D + N E+ S AG + A C+ + +A
Sbjct: 624 KKLLGSLASVFVRLPCGGVGVDSDTIWN--EVHS--AGAARLAVGCVVELVFKVATGELK 679
Query: 604 GGW-------HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAY 756
G+ HHA + GFCY N + +A + L+ + IL VD DVHHGNG Q A+
Sbjct: 680 NGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAF 739
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
++ SV +S H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 740 YSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVN 779
>AK122588-1|BAC56929.1| 308|Homo sapiens FLJ00413 protein protein.
Length = 308
Score = 91.1 bits (216), Expect = 5e-18
Identities = 39/90 (43%), Positives = 59/90 (65%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++ A GFC+ N + IA +L+ K IL VD DVHHGNG Q ++ SV +S
Sbjct: 52 HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYIS 111
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+ + G F+PG+G+++++G G GEG++ N
Sbjct: 112 LHRHDDGNFFPGSGAVDEVGAGSGEGFNVN 141
>AF132607-1|AAD29046.1| 1084|Homo sapiens histone deacetylase 4
protein.
Length = 1084
Score = 91.1 bits (216), Expect = 5e-18
Identities = 66/220 (30%), Positives = 108/220 (49%), Gaps = 21/220 (9%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL K + IR A+ E+L HS+ LY + +D
Sbjct: 676 PEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDS 735
Query: 445 DYISNAQDENF------GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC- 603
+ + F G+G D + N E+ S AG + A C+ + +A
Sbjct: 736 KKLLGSLASVFVRLPCGGVGVDSDTIWN--EVHS--AGAARLAVGCVVELVFKVATGELK 791
Query: 604 GGW-------HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAY 756
G+ HHA + GFCY N + +A + L+ + IL VD DVHHGNG Q A+
Sbjct: 792 NGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAF 851
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
++ SV +S H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 852 YSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVN 891
>AC017028-1|AAX93070.1| 1052|Homo sapiens unknown protein.
Length = 1052
Score = 91.1 bits (216), Expect = 5e-18
Identities = 66/220 (30%), Positives = 108/220 (49%), Gaps = 21/220 (9%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL K + IR A+ E+L HS+ LY + +D
Sbjct: 644 PEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDS 703
Query: 445 DYISNAQDENF------GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC- 603
+ + F G+G D + N E+ S AG + A C+ + +A
Sbjct: 704 KKLLGSLASVFVRLPCGGVGVDSDTIWN--EVHS--AGAARLAVGCVVELVFKVATGELK 759
Query: 604 GGW-------HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAY 756
G+ HHA + GFCY N + +A + L+ + IL VD DVHHGNG Q A+
Sbjct: 760 NGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAF 819
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
++ SV +S H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 820 YSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVN 859
>AB006626-1|BAA22957.2| 1097|Homo sapiens KIAA0288 protein protein.
Length = 1097
Score = 91.1 bits (216), Expect = 5e-18
Identities = 66/220 (30%), Positives = 108/220 (49%), Gaps = 21/220 (9%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL K + IR A+ E+L HS+ LY + +D
Sbjct: 689 PEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDS 748
Query: 445 DYISNAQDENF------GIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWC- 603
+ + F G+G D + N E+ S AG + A C+ + +A
Sbjct: 749 KKLLGSLASVFVRLPCGGVGVDSDTIWN--EVHS--AGAARLAVGCVVELVFKVATGELK 804
Query: 604 GGW-------HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAY 756
G+ HHA + GFCY N + +A + L+ + IL VD DVHHGNG Q A+
Sbjct: 805 NGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAF 864
Query: 757 WTTRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
++ SV +S H+++ G F+PG+G+ +++G G G G++ N
Sbjct: 865 YSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVN 904
>AK095820-1|BAC04630.1| 314|Homo sapiens protein ( Homo sapiens
cDNA FLJ38501 fis, clone HCHON1000176, moderately
similar to Histone deacetylase 5. ).
Length = 314
Score = 89.8 bits (213), Expect = 1e-17
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++ S+ +S
Sbjct: 30 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 89
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 90 LHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 119
>AC002410-1|AAS07401.1| 156|Homo sapiens unknown protein.
Length = 156
Score = 89.8 bits (213), Expect = 1e-17
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++ S+ +S
Sbjct: 47 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 106
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+G+ ++G G GEGY+ N
Sbjct: 107 LHRYDEGNFFPGSGAPNEVGTGLGEGYNIN 136
>BC051824-1|AAH51824.1| 1122|Homo sapiens histone deacetylase 5
protein.
Length = 1122
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 705 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 764
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 765 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 824
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++
Sbjct: 825 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYN 883
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
SV +S H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 884 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 921
>AF132608-1|AAD29047.1| 1122|Homo sapiens histone deacetylase 5
protein.
Length = 1122
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 705 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 764
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 765 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 824
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++
Sbjct: 825 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYN 883
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
SV +S H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 884 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 921
>AF039691-1|AAC18040.1| 897|Homo sapiens antigen NY-CO-9 protein.
Length = 897
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 517 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 576
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 577 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 636
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++
Sbjct: 637 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYN 695
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
SV +S H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 696 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 733
>AB177853-1|BAD66831.1| 716|Homo sapiens KIAA0600 splice variant 1
protein.
Length = 716
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 19/218 (8%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 299 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 358
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 359 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 418
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
AI G HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++
Sbjct: 419 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYN 477
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
SV +S H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 478 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 515
>AB011172-1|BAA25526.2| 1080|Homo sapiens KIAA0600 protein protein.
Length = 1080
Score = 87.0 bits (206), Expect = 8e-17
Identities = 38/90 (42%), Positives = 57/90 (63%), Gaps = 3/90 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+ N + I + L+ K +L VD D+HHGNG Q A++ SV +S
Sbjct: 790 HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYIS 849
Query: 787 FHKFEPG-FYPGTGSIEDIGCGDGEGYSCN 873
H+++ G F+PG+G+ E++G G G GY+ N
Sbjct: 850 LHRYDNGNFFPGSGAPEEVGGGPGVGYNVN 879
>BC006453-1|AAH06453.1| 276|Homo sapiens HDAC7A protein protein.
Length = 276
Score = 82.2 bits (194), Expect = 2e-15
Identities = 35/81 (43%), Positives = 53/81 (65%), Gaps = 3/81 (3%)
Frame = +1
Query: 640 GFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-F 810
GFC+ N + IA +L+ K IL VD DVHHGNG Q ++ SV +S H+ + G F
Sbjct: 2 GFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNF 61
Query: 811 YPGTGSIEDIGCGDGEGYSCN 873
+PG+G+++++G G GEG++ N
Sbjct: 62 FPGSGAVDEVGAGSGEGFNVN 82
>AK001032-1|BAA91474.1| 276|Homo sapiens protein ( Homo sapiens
cDNA FLJ10170 fis, clone HEMBA1003690, weakly similar to
HISTONE DEACETYLASE HDA1. ).
Length = 276
Score = 82.2 bits (194), Expect = 2e-15
Identities = 35/81 (43%), Positives = 53/81 (65%), Gaps = 3/81 (3%)
Frame = +1
Query: 640 GFCYVNDIVIAIEKLK--GKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-F 810
GFC+ N + IA +L+ K IL VD DVHHGNG Q ++ SV +S H+ + G F
Sbjct: 2 GFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNF 61
Query: 811 YPGTGSIEDIGCGDGEGYSCN 873
+PG+G+++++G G GEG++ N
Sbjct: 62 FPGSGAVDEVGAGSGEGFNVN 82
>BC069243-1|AAH69243.1| 1215|Homo sapiens HDAC6 protein protein.
Length = 1215
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 539 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 594
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 595 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 653
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 654 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 706
Score = 72.1 bits (169), Expect = 2e-12
Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 9/225 (4%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD+ + RL A+ + +L+ GL+ + ++ A E+L + HS Y++
Sbjct: 100 LWDDSFPEGPERLHAI--KEQLIQE-----GLLDRCVSFQARFAEKEELMLVHSLEYID- 151
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA---D 585
L + T Y++ + YD + PN + + +A GSV +G
Sbjct: 152 LMETTQ----YMNEGELRVLADTYDSVYLHPNSYSC-ACLASGSVLRLVDAVLGAEIRNG 206
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYW 759
+AI G HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q +
Sbjct: 207 MAIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFD 265
Query: 760 TTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + G G G+GY+ N P N
Sbjct: 266 QDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 310
>BC013737-1|AAH13737.1| 1063|Homo sapiens HDAC6 protein protein.
Length = 1063
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 327 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 386
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 387 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 442
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 443 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 501
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 502 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 554
Score = 67.3 bits (157), Expect = 7e-11
Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q + SV S
Sbjct: 63 HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFS 122
Query: 787 FHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
H++E G F+P + G G G+GY+ N P N
Sbjct: 123 IHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 158
>AJ011972-1|CAA09893.1| 1215|Homo sapiens histone deacetylase-like
protein protein.
Length = 1215
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 539 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 594
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 595 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 653
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 654 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 706
Score = 72.1 bits (169), Expect = 2e-12
Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 9/225 (4%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD+ + RL A+ + +L+ GL+ + ++ A E+L + HS Y++
Sbjct: 100 LWDDSFPEGPERLHAI--KEQLIQE-----GLLDRCVSFQARFAEKEELMLVHSLEYID- 151
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA---D 585
L + T Y++ + YD + PN + + +A GSV +G
Sbjct: 152 LMETTQ----YMNEGELRVLADTYDSVYLHPNSYSC-ACLASGSVLRLVDAVLGAEIRNG 206
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYW 759
+AI G HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q +
Sbjct: 207 MAIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFD 265
Query: 760 TTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + G G G+GY+ N P N
Sbjct: 266 QDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 310
>AF174499-1|AAF36540.1| 1066|Homo sapiens GR AF-1 specific histone
deacetylase protein.
Length = 1066
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 330 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 389
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 390 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 445
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 446 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 504
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 505 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 557
Score = 66.1 bits (154), Expect = 2e-10
Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA ++ +G+C N + +A + K + + +L +D DVHHG G Q + SV S
Sbjct: 66 HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLILDWDVHHGQGTQFTFDQDPSVLYFS 125
Query: 787 FHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
H++E G F+P + G G G+GY+ N P N
Sbjct: 126 IHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 161
>AF132609-1|AAD29048.1| 1215|Homo sapiens histone deacetylase 6
protein.
Length = 1215
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 539 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 594
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 595 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 653
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 654 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 706
Score = 72.1 bits (169), Expect = 2e-12
Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 9/225 (4%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD+ + RL A+ + +L+ GL+ + ++ A E+L + HS Y++
Sbjct: 100 LWDDSFPEGPERLHAI--KEQLIQE-----GLLDRCVSFQARFAEKEELMLVHSLEYID- 151
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA---D 585
L + T Y++ + YD + PN + + +A GSV +G
Sbjct: 152 LMETTQ----YMNEGELRVLADTYDSVYLHPNSYSC-ACLASGSVLRLVDAVLGAEIRNG 206
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYW 759
+AI G HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q +
Sbjct: 207 MAIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFD 265
Query: 760 TTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + G G G+GY+ N P N
Sbjct: 266 QDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 310
>AB020708-1|BAA74924.2| 1233|Homo sapiens KIAA0901 protein protein.
Length = 1233
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 497 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 556
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 557 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 612
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 613 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 671
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + SV +S H+++ G F+P G+ IG G G++ N N
Sbjct: 672 NGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 724
Score = 72.1 bits (169), Expect = 2e-12
Identities = 64/225 (28%), Positives = 105/225 (46%), Gaps = 9/225 (4%)
Frame = +1
Query: 238 LWDEKLVKECIRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEH 417
LWD+ + RL A+ + +L+ GL+ + ++ A E+L + HS Y++
Sbjct: 118 LWDDSFPEGPERLHAI--KEQLIQE-----GLLDRCVSFQARFAEKEELMLVHSLEYID- 169
Query: 418 LKQITDIDDDYISNAQDENFGIGYDCPPV-PNMFELVSTIAGGSVTAAKCLTMGIA---D 585
L + T Y++ + YD + PN + + +A GSV +G
Sbjct: 170 LMETTQ----YMNEGELRVLADTYDSVYLHPNSYSC-ACLASGSVLRLVDAVLGAEIRNG 224
Query: 586 IAINWCGGWHHAHNNRAEGFCYVNDIVIAIE--KLKGKFKNILYVDLDVHHGNGVQDAYW 759
+AI G HHA ++ +G+C N + +A + K + + +L VD DVHHG G Q +
Sbjct: 225 MAIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFD 283
Query: 760 TTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
SV S H++E G F+P + G G G+GY+ N P N
Sbjct: 284 QDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 328
>AK127118-1|BAC86838.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ45175 fis, clone BRAWH3046424, highly similar
to Histone deacetylase 6. ).
Length = 632
Score = 80.6 bits (190), Expect = 7e-15
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = +1
Query: 223 ARVAYLWDEKLVKEC----IRLPAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNV 390
+R ++D+ ++ C P V R + +E GL + + PA+ +L
Sbjct: 127 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 186
Query: 391 FHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLT 570
HS Y+ HL+ + + + + NF Y CP + F G + + +
Sbjct: 187 CHSAEYVGHLRATEKMKTREL-HRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 242
Query: 571 MG--IADIAINWCGGWHHAHNNRAEGFCYVNDIVIAI---EKLKGKFKNILYVDLDVHHG 735
G + A+ G HHA + A GFC+ N + +A + + G IL VD DVHHG
Sbjct: 243 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHG 301
Query: 736 NGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGCGDGEGYSCNFPLN 885
NG Q + +V +S H+++ G F+P G+ IG G G++ N N
Sbjct: 302 NGTQHMFEDDPNVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN 354
>AY032738-1|AAK66822.1| 879|Homo sapiens histone deacetylase 9a
protein.
Length = 879
Score = 79.8 bits (188), Expect = 1e-14
Identities = 59/207 (28%), Positives = 103/207 (49%), Gaps = 19/207 (9%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL++K + I+ AS E++ + HS+ LY + +D
Sbjct: 655 PEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDP 714
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFEL--VSTIAGGSVT--AAKCLTMGIAD-I 588
+ + F G+G D + N + +A G V A+K + + +
Sbjct: 715 RILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGF 774
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWT 762
A+ G HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++
Sbjct: 775 AVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYA 833
Query: 763 TRSVYTLSFHKFEPG-FYPGTGSIEDI 840
S+ +S H+++ G F+PG+G+ ++
Sbjct: 834 DPSILYISLHRYDEGNFFPGSGAPNEV 860
>AC002410-2|AAS07402.1| 144|Homo sapiens unknown protein.
Length = 144
Score = 74.9 bits (176), Expect = 3e-13
Identities = 32/79 (40%), Positives = 50/79 (63%), Gaps = 3/79 (3%)
Frame = +1
Query: 613 HHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVDLDVHHGNGVQDAYWTTRSVYTLS 786
HHA + A GFC+ N + I + L+ + IL VDLDVHHGNG Q A++ S+ +S
Sbjct: 47 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 106
Query: 787 FHKFEPG-FYPGTGSIEDI 840
H+++ G F+PG+G+ ++
Sbjct: 107 LHRYDEGNFFPGSGAPNEV 125
>CR456465-1|CAG30351.1| 669|Homo sapiens dJ402G11.7 protein.
Length = 669
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>BC125083-1|AAI25084.1| 669|Homo sapiens histone deacetylase 10
protein.
Length = 669
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AL022328-11|CAB63048.1| 673|Homo sapiens protein ( Human DNA
sequence from clone RP3-402G11 on chromosome
22q13.31-13.33. ).
Length = 673
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AF426160-1|AAL30513.1| 669|Homo sapiens histone deacetylase 10
protein.
Length = 669
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AF407273-1|AAK92206.1| 649|Homo sapiens histone deacetylase 10
isoform beta protein.
Length = 649
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AF407272-1|AAK92205.1| 669|Homo sapiens histone deacetylase 10
isoform alpha protein.
Length = 669
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AF393962-1|AAK84023.1| 669|Homo sapiens histone deacetylase 10
isoform b protein.
Length = 669
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>AY450395-1|AAS48345.1| 396|Homo sapiens histone deacetylase 10
protein.
Length = 396
Score = 71.7 bits (168), Expect = 3e-12
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = +1
Query: 328 GLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQDENFGIGYDCPPVP 507
GL + + + AS E+L + HS Y+ +++ + + + + I + P
Sbjct: 42 GLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDTIYFH----P 97
Query: 508 NMFELVSTIAGGSVTAAKCLTMGIAD--IAINWCGGWHHAHNNRAEGFCYVNDIVIAIEK 681
+ F AG + + G +A+ G HH A GFC N++ IA
Sbjct: 98 STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAANGFCVFNNVAIAAAH 156
Query: 682 LKGK--FKNILYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPG-FYP--GTGSIEDIGC 846
K K IL VD DVHHG G+Q + SV S+H++E G F+P + +G
Sbjct: 157 AKQKHGLHRILVVDWDVHHGRGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGR 216
Query: 847 GDGEGYSCNFPLN 885
G G G++ N P N
Sbjct: 217 GQGLGFTVNLPWN 229
>BC009676-1|AAH09676.1| 347|Homo sapiens histone deacetylase 11
protein.
Length = 347
Score = 60.9 bits (141), Expect = 6e-09
Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
G+ V N ++ L+S ++ + AS EDL V H+ YL LK + I+
Sbjct: 40 GKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVAT--ITEIPP 97
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
F + + + T GG++ A K AIN GG+HH ++R GFC
Sbjct: 98 VIFLPNFLVQR--KVLRPLRTQTGGTIMAGKLAVE--RGWAINVGGGFHHCSSDRGGGFC 153
Query: 649 YVNDIVIAIEKLKGKFKNI---LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
DI +AI+ L + + I +DLD H GNG + + + VY + + YPG
Sbjct: 154 AYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDV--YNRHIYPG 211
>AK025890-1|BAB15272.1| 347|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22237 fis, clone HRC02058. ).
Length = 347
Score = 60.9 bits (141), Expect = 6e-09
Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
Frame = +1
Query: 289 GRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSDLYLEHLKQITDIDDDYISNAQD 468
G+ V N ++ L+S ++ + AS EDL V H+ YL LK + I+
Sbjct: 40 GKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVAT--ITEIPP 97
Query: 469 ENFGIGYDCPPVPNMFELVSTIAGGSVTAAKCLTMGIADIAINWCGGWHHAHNNRAEGFC 648
F + + + T GG++ A K AIN GG+HH ++R GFC
Sbjct: 98 VIFLPNFLVQR--KVLRPLRTQTGGTIMAGKLAVE--RGWAINVGGGFHHCSSDRGGGFC 153
Query: 649 YVNDIVIAIEKLKGKFKNI---LYVDLDVHHGNGVQDAYWTTRSVYTLSFHKFEPGFYPG 819
DI +AI+ L + + I +DLD H GNG + + + VY + + YPG
Sbjct: 154 AYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDV--YNRHIYPG 211
>CR457341-1|CAG33622.1| 225|Homo sapiens HDAC11 protein.
Length = 225
Score = 52.8 bits (121), Expect = 2e-06
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Frame = +1
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNI---LYVDLDVHHGNGVQDAYW 759
AIN GG+HH ++R GFC DI +AI+ L + + I +DLD H GNG + +
Sbjct: 12 AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFM 71
Query: 760 TTRSVYTLSFHKFEPGFYPG 819
+ VY + + YPG
Sbjct: 72 DDKRVYIMDV--YNRHIYPG 89
>AK025426-1|BAB15127.1| 225|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21773 fis, clone COLF7849. ).
Length = 225
Score = 52.8 bits (121), Expect = 2e-06
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Frame = +1
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFKNI---LYVDLDVHHGNGVQDAYW 759
AIN GG+HH ++R GFC DI +AI+ L + + I +DLD H GNG + +
Sbjct: 12 AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFM 71
Query: 760 TTRSVYTLSFHKFEPGFYPG 819
+ VY + + YPG
Sbjct: 72 DDKRVYIMDV--YNRHIYPG 89
>AK027734-1|BAB55329.1| 191|Homo sapiens protein ( Homo sapiens
cDNA FLJ14828 fis, clone OVARC1000915, highly similar to
Homo sapiens histone deacetylase 5 mRNA. ).
Length = 191
Score = 33.1 bits (72), Expect = 1.4
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 18/165 (10%)
Frame = +1
Query: 277 PAVFGRARLVHNLIEAYGLISKLKVIRSSPASYEDLNVFHSD----LYLEHLKQITDIDD 444
P GR + + + ++ GL+SK + IR A+ +++ HS+ LY +D
Sbjct: 15 PEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDS 74
Query: 445 DYISNAQDENF-------GIGYDCPPVPNMFELVSTI---AGGSVTAAKCLTMGIAD--I 588
+ + GIG D V N S + G + A + G
Sbjct: 75 KKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGF 134
Query: 589 AINWCGGWHHAHNNRAEGFCYVNDIVIAIEKLKGKFK--NILYVD 717
AI G HHA + A GFC+ N + I + L+ K +L VD
Sbjct: 135 AIIRPPG-HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVD 178
>AY034072-1|AAK56405.1| 2713|Homo sapiens chromodomain helicase DNA
binding protein 5 protein.
Length = 2713
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 1186 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1235
>AL121674-2|CAI21744.1| 2715|Homo sapiens chromodomain helicase DNA
binding protein 6 protein.
Length = 2715
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 1188 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1237
>AL031669-3|CAI22255.1| 2715|Homo sapiens chromodomain helicase DNA
binding protein 6 protein.
Length = 2715
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 1188 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1237
>AL031667-8|CAI42983.1| 524|Homo sapiens chromodomain helicase DNA
binding protein 6 protein.
Length = 524
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 373 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 422
>AL031667-2|CAI42977.1| 2715|Homo sapiens chromodomain helicase DNA
binding protein 6 protein.
Length = 2715
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 1188 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1237
>AK026022-1|BAB15325.1| 757|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22369 fis, clone HRC06676. ).
Length = 757
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 411 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 460
>AF525085-1|AAN59903.1| 488|Homo sapiens RIGB protein.
Length = 488
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 337 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 386
>AB037756-1|BAA92573.2| 2041|Homo sapiens KIAA1335 protein protein.
Length = 2041
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = -1
Query: 853 RXRNQCLLYSLYLDRNLVRTCGKTMCILTESSNKHLEHHCHDAHLNQRIKY 701
+ +NQ L+ L D + + TC + + + KHL+ HC+ L R+ Y
Sbjct: 514 KTKNQLLIPELK-DADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 563
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 123,426,337
Number of Sequences: 237096
Number of extensions: 2724719
Number of successful extensions: 5635
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 5098
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5481
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11492727354
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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