Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP23_F_P01
(1230 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4RFL9 Cluster: Chromosome undetermined SCAF15114, whol... 299 7e-80
UniRef50_Q8NEB9 Cluster: Phosphatidylinositol 3-kinase catalytic... 299 1e-79
UniRef50_Q9W1M7 Cluster: CG5373-PA; n=3; Sophophora|Rep: CG5373-... 283 9e-75
UniRef50_UPI0000DB7C6C Cluster: PREDICTED: similar to Phosphotid... 260 5e-68
UniRef50_Q7PMF0 Cluster: ENSANGP00000002906; n=2; Coelomata|Rep:... 246 1e-63
UniRef50_Q4PHG0 Cluster: Putative uncharacterized protein; n=1; ... 153 9e-36
UniRef50_P54676 Cluster: Phosphatidylinositol 3-kinase VPS34-lik... 149 1e-34
UniRef50_Q5KM37 Cluster: Phosphatidylinositol 3-kinase, putative... 137 6e-31
UniRef50_Q2U4A1 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 130 9e-29
UniRef50_A4RAX1 Cluster: Putative uncharacterized protein; n=3; ... 121 3e-26
UniRef50_A6S8M7 Cluster: Putative uncharacterized protein; n=2; ... 107 6e-22
UniRef50_A2YTT1 Cluster: Putative uncharacterized protein; n=2; ... 105 2e-21
UniRef50_P42339 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 102 2e-20
UniRef50_Q6C299 Cluster: Yarrowia lipolytica chromosome F of str... 97 8e-19
UniRef50_A7T8J7 Cluster: Predicted protein; n=1; Nematostella ve... 83 2e-14
UniRef50_O04270 Cluster: Phosphatidylinositol 3-kinase; n=1; Chl... 72 4e-11
UniRef50_Q9TXI7 Cluster: Related to yeast vacuolar protein sorti... 65 3e-09
UniRef50_A5DM56 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08
UniRef50_Q9Y8E4 Cluster: Phosphatidylinositol 3-kinase Pdd1p; n=... 57 1e-06
UniRef50_P22543 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 56 2e-06
UniRef50_Q92213 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 53 1e-05
UniRef50_A3LQL4 Cluster: 1-phosphatidylinositol 3-kinase; n=2; S... 53 2e-05
UniRef50_A5BD75 Cluster: Putative uncharacterized protein; n=1; ... 52 4e-05
UniRef50_Q01CW4 Cluster: Phosphatidylinositol 3-kinase; n=2; cel... 51 5e-05
UniRef50_Q6CQA2 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 48 4e-04
UniRef50_UPI00004993D5 Cluster: phosphatidylinositol 3-kinase; n... 45 0.003
UniRef50_Q4SRM6 Cluster: Chromosome undetermined SCAF14516, whol... 44 0.006
UniRef50_Q57YM2 Cluster: Phosphatidylinositol 3-kinase, putative... 44 0.006
UniRef50_P42336 Cluster: Phosphatidylinositol-4,5-bisphosphate 3... 44 0.006
UniRef50_A2DJM8 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 43 0.014
UniRef50_A0E0Q4 Cluster: Chromosome undetermined scaffold_72, wh... 43 0.019
UniRef50_UPI00006CFDD2 Cluster: Phosphatidylinositol 3- and 4-ki... 42 0.033
UniRef50_Q241V8 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 42 0.033
UniRef50_P54675 Cluster: Phosphatidylinositol 3-kinase 3; n=5; E... 42 0.043
UniRef50_Q4T9W9 Cluster: Chromosome undetermined SCAF7485, whole... 41 0.057
UniRef50_Q22H25 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 39 0.30
UniRef50_Q2Y888 Cluster: Putative uncharacterized protein; n=1; ... 38 0.40
UniRef50_A0DLV0 Cluster: Chromosome undetermined scaffold_556, w... 38 0.53
UniRef50_O00443 Cluster: Phosphatidylinositol-4-phosphate 3-kina... 38 0.53
UniRef50_A2FAC3 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 38 0.70
UniRef50_Q1L913 Cluster: Novel protein similar to vertebrate pho... 37 0.93
UniRef50_A7RRA6 Cluster: Predicted protein; n=2; Nematostella ve... 37 0.93
UniRef50_A0D2V1 Cluster: Chromosome undetermined scaffold_35, wh... 37 0.93
UniRef50_UPI0000F21165 Cluster: PREDICTED: hypothetical protein;... 37 1.2
UniRef50_Q237I3 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 36 2.1
UniRef50_A7B576 Cluster: Putative uncharacterized protein; n=1; ... 36 2.8
UniRef50_P48736 Cluster: Phosphatidylinositol-4,5-bisphosphate 3... 36 2.8
UniRef50_O00750 Cluster: Phosphatidylinositol-4-phosphate 3-kina... 36 2.8
UniRef50_UPI0000498E9A Cluster: phosphatidylinositol 3-kinase; n... 35 3.7
UniRef50_Q9KB22 Cluster: ABC transporter; n=9; Firmicutes|Rep: A... 35 3.7
UniRef50_A4XN07 Cluster: Binding-protein-dependent transport sys... 35 3.7
UniRef50_A0DT78 Cluster: Chromosome undetermined scaffold_62, wh... 35 3.7
UniRef50_Q2T981 Cluster: Putative uncharacterized protein; n=1; ... 35 4.9
UniRef50_Q3S4D5 Cluster: LysR-like regular protein; n=1; Polarom... 35 4.9
UniRef50_UPI0000F2E101 Cluster: PREDICTED: similar to AFF3 prote... 34 6.5
UniRef50_UPI0000EB073C Cluster: Rho GTPase-activating protein 22... 34 6.5
UniRef50_Q14M65 Cluster: Hypothetical oligopeptide abc transport... 34 6.5
UniRef50_Q8WXI7 Cluster: Mucin-16; n=23; cellular organisms|Rep:... 34 6.5
UniRef50_Q1FGG3 Cluster: Binding-protein-dependent transport sys... 34 8.6
UniRef50_A0H454 Cluster: Binding-protein-dependent transport sys... 34 8.6
>UniRef50_Q4RFL9 Cluster: Chromosome undetermined SCAF15114, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF15114, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 989
Score = 299 bits (735), Expect = 7e-80
Identities = 137/220 (62%), Positives = 164/220 (74%), Gaps = 5/220 (2%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
DKF YVYS LD V++KIG+LEGKR + Y LL DPML+FSGLYQ+ CSDLYVTCQ+
Sbjct: 3 DKFNYVYSCDLDINVQLKIGSLEGKREQKSYKALLEDPMLRFSGLYQENCSDLYVTCQVF 62
Query: 388 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGG 567
++G+PLALPV T+YKAF+TRWNWNEW+ LPV Y DLP+NA +A+T++D GPGK + VGG
Sbjct: 63 AEGKPLALPVRTSYKAFSTRWNWNEWLRLPVKYPDLPQNAQVALTVWDIYGPGKAVPVGG 122
Query: 568 TTISIFGKHGMLRQGMFDLRVWPGVEGSEKTPGKAPDR-----GKEQMQRLAKLAKKHRN 732
TT+++FGK+GM RQGM DL+VWPGVEG P P R ++QM RLAKL K HR
Sbjct: 123 TTVTLFGKYGMFRQGMHDLKVWPGVEGDGGDPTATPGRTSSSLTEDQMGRLAKLTKAHRQ 182
Query: 733 GHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXPXV 852
GH+ KV WLDRLT REI M NE R N MYLM E P V
Sbjct: 183 GHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFPRV 222
>UniRef50_Q8NEB9 Cluster: Phosphatidylinositol 3-kinase catalytic
subunit type 3; n=37; Eukaryota|Rep:
Phosphatidylinositol 3-kinase catalytic subunit type 3 -
Homo sapiens (Human)
Length = 887
Score = 299 bits (733), Expect = 1e-79
Identities = 138/216 (63%), Positives = 166/216 (76%), Gaps = 5/216 (2%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
+KF+Y+YS LD V++KIG+LEGKR + Y +L DPMLKFSGLYQ+ CSDLYVTCQ+
Sbjct: 5 EKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVF 64
Query: 388 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGG 567
++G+PLALPV T+YKAF+TRWNWNEW+ LPV Y DLPRNA +A+TI+D GPGK + VGG
Sbjct: 65 AEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGG 124
Query: 568 TTISIFGKHGMLRQGMFDLRVWPGVE--GSE--KTPGKAPDR-GKEQMQRLAKLAKKHRN 732
TT+S+FGK+GM RQGM DL+VWP VE GSE KTPG+ ++QM RLAKL K HR
Sbjct: 125 TTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQ 184
Query: 733 GHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXE 840
GH+ KV WLDRLT REI M NE R N MYLM E
Sbjct: 185 GHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVE 220
>UniRef50_Q9W1M7 Cluster: CG5373-PA; n=3; Sophophora|Rep: CG5373-PA
- Drosophila melanogaster (Fruit fly)
Length = 949
Score = 283 bits (693), Expect = 9e-75
Identities = 127/226 (56%), Positives = 166/226 (73%), Gaps = 4/226 (1%)
Frame = +1
Query: 193 MNEIDDKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYV 372
M++ DD F Y++SSSL +V+IK+GTLEGK+ +P+Y+KLL DP+L+FSGLY + V
Sbjct: 1 MDQPDDHFRYIHSSSLHERVQIKVGTLEGKKRQPDYEKLLEDPILRFSGLYSEEHPSFQV 60
Query: 373 TCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKV 552
Q+ + G P LPV ++YKAF RW+WNEWVTLP+ +SDLPR+A+L +TI DC+G G+
Sbjct: 61 RLQVFNQGRPYCLPVTSSYKAFGKRWSWNEWVTLPLQFSDLPRSAMLVLTILDCSGAGQT 120
Query: 553 MVVGGTTISIFGKHGMLRQGMFDLRVWPGVEGS----EKTPGKAPDRGKEQMQRLAKLAK 720
V+GGT+IS+FGK GM RQGM+DLRVW GVEG +TPGK + K QMQRL KLAK
Sbjct: 121 TVIGGTSISMFGKDGMFRQGMYDLRVWLGVEGDGNFPSRTPGKGKESSKSQMQRLGKLAK 180
Query: 721 KHRNGHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXPXVXI 858
KHRNG + KV WLDRLT REI + NE+ R + M+LM E P + +
Sbjct: 181 KHRNGQVQKVDWLDRLTFREIEVINEREKRMSDYMFLMIEFPAIVV 226
>UniRef50_UPI0000DB7C6C Cluster: PREDICTED: similar to
Phosphotidylinositol 3 kinase 59F CG5373-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to
Phosphotidylinositol 3 kinase 59F CG5373-PA - Apis
mellifera
Length = 774
Score = 260 bits (637), Expect = 5e-68
Identities = 129/228 (56%), Positives = 156/228 (68%), Gaps = 4/228 (1%)
Frame = +1
Query: 193 MNEIDDKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYV 372
M +I+DKF+YVYSSSLD +++IKIGTLE G DL
Sbjct: 2 MEDINDKFFYVYSSSLDTRIQIKIGTLEAN----------------------GGRGDLAA 39
Query: 373 TCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKV 552
+ Q+ + G PLALPV T YK FT+RWNWN+WVTLP+ YSDLPR+A L +++YDCAGPG+
Sbjct: 40 SLQVWAGGRPLALPVHTAYKHFTSRWNWNQWVTLPISYSDLPRDAQLCISLYDCAGPGRQ 99
Query: 553 MVVGGTTISIFGKHGMLRQGMFDLRVWPGVE--GS--EKTPGKAPDRGKEQMQRLAKLAK 720
+ +GGTTIS+FGKHG+ RQGM DLRVWPGVE GS TPGK D GKEQMQRLAKL K
Sbjct: 100 LPIGGTTISMFGKHGVFRQGMLDLRVWPGVEADGSIPNSTPGKTRDHGKEQMQRLAKLVK 159
Query: 721 KHRNGHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXPXVXIXG 864
KHRNG + KV WLDRLT REI + NE+ R +YLM E P + + G
Sbjct: 160 KHRNGQMNKVDWLDRLTFREIELINEREKRASEYLYLMIEFPEITMDG 207
>UniRef50_Q7PMF0 Cluster: ENSANGP00000002906; n=2; Coelomata|Rep:
ENSANGP00000002906 - Anopheles gambiae str. PEST
Length = 924
Score = 246 bits (601), Expect = 1e-63
Identities = 117/218 (53%), Positives = 152/218 (69%), Gaps = 5/218 (2%)
Frame = +1
Query: 220 YVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGE 399
Y+ SSSL K+ IKIGTLEG+ Y+KL+ P+LKFSG+Y + L V QI +GE
Sbjct: 9 YIGSSSLLQKISIKIGTLEGENVGYSYEKLIEQPLLKFSGMYTEKTPPLKVKLQIFDNGE 68
Query: 400 PLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCA-GPGKVMVVGGTTI 576
P+ LPV T++K FTTRW+WNEWVTLP+ ++D+ R A+L +TIYDCA G ++ VVGGT+I
Sbjct: 69 PVGLPVCTSHKHFTTRWSWNEWVTLPLRFTDISRTAVLGLTIYDCAGGREQLTVVGGTSI 128
Query: 577 SIFGKHGMLRQGMFDLRVWPGVEG----SEKTPGKAPDRGKEQMQRLAKLAKKHRNGHLP 744
S F +G+ RQG++DL+VWP +E + TPGKA G QMQRL+KLAKKHRNG +
Sbjct: 129 SFFSTNGLFRQGLYDLKVWPQMEPDGACNSITPGKAITTGVHQMQRLSKLAKKHRNGQME 188
Query: 745 KVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXPXVXI 858
K+ WLDRLT RE+ + NE R +YLM E P V I
Sbjct: 189 KIDWLDRLTFRELEVINEMEKRNSQFLYLMVEFPQVYI 226
>UniRef50_Q4PHG0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 975
Score = 153 bits (371), Expect = 9e-36
Identities = 80/220 (36%), Positives = 120/220 (54%), Gaps = 5/220 (2%)
Frame = +1
Query: 202 IDDKFY-YVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTC 378
+D FY +V S L+ + +I +L+G+ + +LL P + G Q DL V C
Sbjct: 1 MDRDFYSFVRLSDLNLNLTFRISSLQGRLDRLTRTQLLEKPESRHWGSQQSQFPDLIVEC 60
Query: 379 QILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMV 558
++ SD +PL++PV T YK F WNEW+TLP DLP A + TIY+ A +
Sbjct: 61 RLYSDNKPLSVPVRTAYKPFRNNHQWNEWITLPYKLCDLPLGAQITFTIYEVALSNASRI 120
Query: 559 VGGTTISIFGKHGMLRQGMFDLRVWPGV--EGS--EKTPGKAPDRGKEQMQRLAKLAKKH 726
+GGTT+ +FGK G L+ L VW GV +GS TP K + K++M RL KL K+H
Sbjct: 121 IGGTTLPLFGKKGTLKSAQHRLFVWKGVKADGSIESATPSKVGEM-KDEMGRLEKLIKRH 179
Query: 727 RNGHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXP 846
G LP+V WLD++ R++ + + + ++L + P
Sbjct: 180 ERGDLPRVDWLDKMAYRQVEKVYQAESQSSDRLFLYIDLP 219
>UniRef50_P54676 Cluster: Phosphatidylinositol 3-kinase VPS34-like;
n=2; Dictyostelium discoideum|Rep: Phosphatidylinositol
3-kinase VPS34-like - Dictyostelium discoideum (Slime
mold)
Length = 816
Score = 149 bits (362), Expect = 1e-34
Identities = 87/223 (39%), Positives = 126/223 (56%), Gaps = 9/223 (4%)
Frame = +1
Query: 205 DDKFYYVYSSSLDYKVEIKIGTLEGKRTK---PE-YDKLLSDPMLKFSGLYQDGCSDLYV 372
D KFYY SS + K +IK+ TLEGKR K PE DK + DP LK+S LY+D DLY+
Sbjct: 6 DFKFYY--SSDIPIKYKIKLCTLEGKRNKENAPETVDKWIDDPYLKYSSLYRDTTIDLYI 63
Query: 373 TCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKV 552
TC + SDG+ L+ T+Y F+ W+E + P+ + DLP + ++ +TI+D P K
Sbjct: 64 TCTLYSDGKQLSTSEHTSYNPFSVSNKWDETIIFPLKHQDLPFDTMIVITIWDIYSPMKK 123
Query: 553 MVVGGTTISIFGKHGMLRQGMFDLRVWPGVEG-SEK---TPGKAPDRGKEQMQRLAKLAK 720
+ +GGT+ +IFG + + R+G L +W EG EK TPG+ +GK++ RL KL K
Sbjct: 124 VPIGGTSFNIFGMNKIERKGKHKLLIWQDREGDGEKETTTPGQI--QGKDEQYRLEKLKK 181
Query: 721 KHRNGHLPKVXWLDRLTXREI-XMXNEKXXRXXNXMYLMXEXP 846
K+ + WLD+ + EI + N +YL E P
Sbjct: 182 KYDRKLINHCQWLDKFSLNEIERLSRASESLNKNQIYLTIELP 224
>UniRef50_Q5KM37 Cluster: Phosphatidylinositol 3-kinase, putative;
n=1; Filobasidiella neoformans|Rep: Phosphatidylinositol
3-kinase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 918
Score = 137 bits (331), Expect = 6e-31
Identities = 72/197 (36%), Positives = 107/197 (54%), Gaps = 4/197 (2%)
Frame = +1
Query: 268 TLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGEPLALPVMTTYKAFTTR 447
+L+G K + + L P L GL Q SDLYVTCQ+ +DG+ +LP T +K F
Sbjct: 70 SLQGSLPKHPFSRTLHSPALAHQGLQQQTPSDLYVTCQLWADGKQYSLPFRTAHKDFPRG 129
Query: 448 WNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLR 627
+ WN V P+ Y L ++ +A TI+D G GK + VGGTT+S+F L++G L
Sbjct: 130 YTWNSVVVFPITYPSLLLSSQIAFTIWDVQGSGKAVPVGGTTMSLFNSKRTLKRGQQRLH 189
Query: 628 VWPGVEG----SEKTPGKAPDRGKEQMQRLAKLAKKHRNGHLPKVXWLDRLTXREIXMXN 795
V GV+ + TP + PD +++M RL +L K G + K+ WLDRLT R+I +
Sbjct: 190 VHRGVQADPSLNTTTPSELPDEEEDEMGRLERLVKDFERGDILKIDWLDRLTFRQIEKAH 249
Query: 796 EKXXRXXNXMYLMXEXP 846
+ + +YL + P
Sbjct: 250 SATEK-SDSLYLYVDLP 265
>UniRef50_Q2U4A1 Cluster: Phosphatidylinositol 3-kinase VPS34; n=14;
Pezizomycotina|Rep: Phosphatidylinositol 3-kinase VPS34
- Aspergillus oryzae
Length = 902
Score = 130 bits (313), Expect = 9e-29
Identities = 69/216 (31%), Positives = 119/216 (55%), Gaps = 24/216 (11%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
+ F + S+ +D+ ++IKIG+LEGK+ + + LL P L+ G Q+ SDL+VT Q+
Sbjct: 2 EAFTFAVSTQVDFPIQIKIGSLEGKQKEVPFSILLKRPELRHLGSVQNPTSDLFVTVQLW 61
Query: 388 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCA------GPGK 549
SD +PL +P+ T+Y+ F + WNEW+ +P+ D P LA+TI+D + G
Sbjct: 62 SDSKPLGVPLQTSYRTFKSVRAWNEWLQMPMSLKDAPYKCQLAITIWDLSPFGGEGAQGH 121
Query: 550 VMVVGGTTISIFGKHGMLRQGMFDLRVW-------------PGVEGSEKTPGKAPD---- 678
+ GGTTIS+F + G L+ G +V+ P + +++ APD
Sbjct: 122 YVPFGGTTISLFDEEGKLKMGRQKCKVYRHKAADGFSSTTTPSIPSTKRRKANAPDPLGP 181
Query: 679 -RGKEQMQRLAKLAKKHRNGHLPKVXWLDRLTXREI 783
+ +++R+ L KKH G +P++ W+D++ R++
Sbjct: 182 SPEEIELERVEVLIKKHEMGEIPRIDWMDQMVFRQL 217
>UniRef50_A4RAX1 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 927
Score = 121 bits (292), Expect = 3e-26
Identities = 75/218 (34%), Positives = 108/218 (49%), Gaps = 28/218 (12%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
+ F + S +LD+ + ++I LEG + LL P L+ G SDLYVT Q+
Sbjct: 5 EPFSFGSSDALDFPISVRIINLEGDEIPYHFSTLLQHPELRHVGSNMSPNSDLYVTVQVW 64
Query: 388 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCA---------- 537
+ +PL +PV T YKAF T WNEW+TLP+ Y D+P NA LA+TI+D +
Sbjct: 65 AGSKPLTVPVQTAYKAFKTERRWNEWLTLPIKYCDVPLNAHLAITIWDLSPQPGEGERDQ 124
Query: 538 GPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPG--VEGSE--KTP-------------- 663
G + GGTT+ +F ++G V +G + KTP
Sbjct: 125 AQGHAVPFGGTTLPLFDGDNQAQKGRQKCHVHRHKLADGCDDTKTPAILLKRRNDPRRKD 184
Query: 664 GKAPDRGKEQMQRLAKLAKKHRNGHLPKVXWLDRLTXR 777
D E+++R+ KL KKH G +P+V WLD+L R
Sbjct: 185 SVVVDEDAEELERMEKLFKKHEMGEIPRVEWLDQLVFR 222
>UniRef50_A6S8M7 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 973
Score = 107 bits (257), Expect = 6e-22
Identities = 66/197 (33%), Positives = 101/197 (51%), Gaps = 26/197 (13%)
Frame = +1
Query: 271 LEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGEPLALPVMTTYKAFTTRW 450
LEG++T + L++ P L+ G SDLYVT Q+ +D +PL +PV T YK+F
Sbjct: 74 LEGEQTPIPFSTLINRPDLRHIGSNLSPHSDLYVTVQLWADSKPLTVPVQTAYKSFKNER 133
Query: 451 NWNEWVTLPVYYSDLPRNAILAMTIYDCA------GPGKVMVVGGTTISIFGKHGMLRQG 612
WNEW+TLP+ S +P ++ +A+T++D + G + GGTT+ +F K L++G
Sbjct: 134 KWNEWLTLPIDCSTIPLSSQVAITVWDLSPTGGDGAQGHAVPFGGTTLRLFDKDNQLQKG 193
Query: 613 --MFDLRVWPGVEG--SEKTPGKAP----------------DRGKEQMQRLAKLAKKHRN 732
L +G S TP P D+ E++ RL KL KKH
Sbjct: 194 RQKCHLHRRKAADGLDSSSTPAVLPNVRRNGSKSKEEAEIIDKEGEELDRLEKLFKKHEM 253
Query: 733 GHLPKVXWLDRLTXREI 783
G + ++ WLD+L R +
Sbjct: 254 GEIARIEWLDQLVFRGV 270
>UniRef50_A2YTT1 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 1047
Score = 105 bits (253), Expect = 2e-21
Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 5/157 (3%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCA-G 540
L+V C + DG L T K+ + + WNE VTL Y DL + LA T++D + G
Sbjct: 62 LFVECTLYIDGVQFGLSTNTRLKSLGSPYCWNELVTLSAKYRDLTPFSHLAFTVWDMSSG 121
Query: 541 PGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPG--VEGS--EKTPGKAPDRGKEQMQRLA 708
+ +VGGTTIS+F L+ G LRVWP +GS TPGK P +E+++RL
Sbjct: 122 EDNIYIVGGTTISLFNSKNQLKTGRLRLRVWPNKMADGSLSTSTPGKVPKTKREEIERLE 181
Query: 709 KLAKKHRNGHLPKVXWLDRLTXREIXMXNEKXXRXXN 819
++A ++ G +P + WLD L ++ R N
Sbjct: 182 RVANQYIRGQIPHIGWLDNLIANAADKLEKESERTEN 218
>UniRef50_P42339 Cluster: Phosphatidylinositol 3-kinase VPS34; n=16;
Magnoliophyta|Rep: Phosphatidylinositol 3-kinase VPS34 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 814
Score = 102 bits (245), Expect = 2e-20
Identities = 51/151 (33%), Positives = 80/151 (52%), Gaps = 4/151 (2%)
Frame = +1
Query: 361 DLYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 540
+LY+ C + DG P LP+ T K + WNE +TL Y DL ++ LA+T++D +
Sbjct: 49 ELYIECALYIDGAPFGLPMRTRLKTTGPPYCWNELITLSSKYRDLTAHSQLAITVWDVSC 108
Query: 541 PGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVE--GS--EKTPGKAPDRGKEQMQRLA 708
++GG T+ +F ++ G LR+W G E GS TPGK P + +++RL
Sbjct: 109 GKTEGLIGGATVLLFNSKMQMKSGKQKLRLWQGKEADGSFPTSTPGKVPRHERGELERLE 168
Query: 709 KLAKKHRNGHLPKVXWLDRLTXREIXMXNEK 801
KL K+ G + + WLDRL + + E+
Sbjct: 169 KLMNKYERGQIQSIDWLDRLMLKSLDTIKEQ 199
>UniRef50_Q6C299 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 801
Score = 97.1 bits (231), Expect = 8e-19
Identities = 64/203 (31%), Positives = 98/203 (48%), Gaps = 10/203 (4%)
Frame = +1
Query: 268 TLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGEPLALPVMTTYKAFTTR 447
+LEG + L DP + D SDL +T Q+ ++G+ L + TTYK+F ++
Sbjct: 4 SLEGTFPLLSLSEQLVDPQKALAKHRVDATSDLTLTAQVWANGKALTGQIATTYKSFKSK 63
Query: 448 WNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIF-GKHGMLRQGMFDL 624
WNEW+ P+ S LP +A + +D G M+V TI F K+ +L +G +
Sbjct: 64 RRWNEWLQFPIRLSQLPLDAEVRFQFWDY--DGNDMLVARATIPFFDSKNAVLLRGRQKV 121
Query: 625 RVWPGVEGSEKTPGKAPDR---------GKEQMQRLAKLAKKHRNGHLPKVXWLDRLTXR 777
V E ++ K D+ G +M RL KL KKH G +P++ WLD L R
Sbjct: 122 DVVIDDEDEQEKENKFNDKTKAIANNNSGYSEMDRLEKLIKKHELGDMPRLDWLDNLAFR 181
Query: 778 EIXMXNEKXXRXXNXMYLMXEXP 846
+I + N K + ++L E P
Sbjct: 182 QIELVNTK-HTTKSDLFLYVEYP 203
>UniRef50_A7T8J7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 162
Score = 82.6 bits (195), Expect = 2e-14
Identities = 40/69 (57%), Positives = 46/69 (66%), Gaps = 3/69 (4%)
Frame = +1
Query: 601 LRQGMFDLRVWPGVEGSEKTPGKAPDRG---KEQMQRLAKLAKKHRNGHLPKVXWLDRLT 771
LR GM DL+VWPGVE K P P + ++QM RLAKL+KKH G + KV WLDRLT
Sbjct: 10 LRHGMHDLKVWPGVEADGKMPTSTPGKTTATEDQMNRLAKLSKKHHKGQMLKVDWLDRLT 69
Query: 772 XREIXMXNE 798
REI M NE
Sbjct: 70 FREIEMINE 78
>UniRef50_O04270 Cluster: Phosphatidylinositol 3-kinase; n=1;
Chlamydomonas reinhardtii|Rep: Phosphatidylinositol
3-kinase - Chlamydomonas reinhardtii
Length = 490
Score = 71.7 bits (168), Expect = 4e-11
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Frame = +1
Query: 454 WNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVW 633
W+EW+T V Y DLP +A L + + + A + +VG + +F K G L+ G L VW
Sbjct: 256 WDEWLTFCVKYRDLPPDAQLVLLLVEAAEGRREALVGSSVTPLFSKRGRLKTGPQRLAVW 315
Query: 634 PG----VEGSEKTPGKAPDRGKEQMQRLAKLAKKHRNGHL---PKVXWLDRLTXREI 783
G + TPGK P ++++ RL L +H+ G + P WLD L EI
Sbjct: 316 EGAPPCTQFPTSTPGKVPLAHRDRLGRLEHLLHRHQRGDMAPGPGGEWLDALALAEI 372
>UniRef50_Q9TXI7 Cluster: Related to yeast vacuolar protein sorting
factor protein 34, isoform a; n=7; Caenorhabditis|Rep:
Related to yeast vacuolar protein sorting factor protein
34, isoform a - Caenorhabditis elegans
Length = 901
Score = 65.3 bits (152), Expect = 3e-09
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 16/214 (7%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
+ F +VYS L V++K+ EG + +L+ P+ + + L+ +++ V C
Sbjct: 11 ESFSFVYSCDLQTNVQVKVAEFEGI-----FRDVLN-PVRRLNQLF----AEITVYCNNQ 60
Query: 388 SDGEPLALPVMTTYKAFTTR-----WNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKV 552
G P+ T + WNEW+TLP+ YSDL R+A L +TI++ V
Sbjct: 61 QIGYPVCTSFHTPPDSSQLARQKLIQKWNEWLTLPIRYSDLSRDAFLHITIWEHEDDEIV 120
Query: 553 -------MVVGGTTISIFGKHGMLRQGMFDLRV----WPGVEGSEKTPGKAPDRGKEQMQ 699
+V + +S+F K G+L+ G+ D+++ P + K D +++
Sbjct: 121 NNSTFSRRLVAQSKLSMFSKRGILKSGVIDVQMNVSTTPDPFVKQPETWKYSDAWGDEID 180
Query: 700 RLAKLAKKHRNGHLPKVXWLDRLTXREIXMXNEK 801
L K + G + V WLD R I M K
Sbjct: 181 LLFKQVTRQSRGLVEDVPWLDPFASRRIEMIRAK 214
>UniRef50_A5DM56 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 958
Score = 62.5 bits (145), Expect = 2e-08
Identities = 44/173 (25%), Positives = 78/173 (45%), Gaps = 1/173 (0%)
Frame = +1
Query: 253 EIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGEPLALPVMTTYK 432
++++ TL K ++P + LS+ + S+ YV QI + P++ PV T+Y+
Sbjct: 34 QVRLATLSEKYSEPSVFRKLSNV---------NATSEFYVQVQIYQENNPISNPVQTSYQ 84
Query: 433 AFTT-RWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQ 609
FT R WN+W+ LP+Y++ L +A + + IY+ +V GT L +
Sbjct: 85 PFTANRRLWNQWLQLPIYFNQLSLSAYIVLAIYEICDTSPSLVGVGTLPMFNTSECTLNK 144
Query: 610 GMFDLRVWPGVEGSEKTPGKAPDRGKEQMQRLAKLAKKHRNGHLPKVXWLDRL 768
G + + + PG G ++ K+ NG V WLD++
Sbjct: 145 GTQKVAI-----RARGLPGSF--EGCCELSSSESNLIKYENGDYKLVPWLDKM 190
>UniRef50_Q9Y8E4 Cluster: Phosphatidylinositol 3-kinase Pdd1p; n=1;
Pichia angusta|Rep: Phosphatidylinositol 3-kinase Pdd1p
- Pichia angusta (Yeast) (Hansenula polymorpha)
Length = 1016
Score = 56.8 bits (131), Expect = 1e-06
Identities = 43/153 (28%), Positives = 78/153 (50%), Gaps = 5/153 (3%)
Frame = +1
Query: 358 SDLYVTCQILSDGEPLALPVMTT--YKAFTTR-WNWNEWVTLPVYYSDLPRNAILAMTIY 528
+++YV + S G+ L +PV+T+ Y + ++ + W+ LP+ YS LP +A+L ++++
Sbjct: 63 NEIYVYVYVESSGKQLTVPVLTSVAYSSGNSKNSSRGNWIHLPIDYSQLPLDAVLVLSLF 122
Query: 529 DCA-GPGKVMVVGGTTISIFGKHGM-LRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQMQR 702
+ G +G + +F + L +G L+V +G KT + + + QMQ
Sbjct: 123 NYKLKTGSENKLGECRLYMFNQENCTLMKGYQRLKV-DFADG--KT--EVDQQKQSQMQI 177
Query: 703 LAKLAKKHRNGHLPKVXWLDRLTXREIXMXNEK 801
L K+ +G + WLD+LT R I N K
Sbjct: 178 LETKLKQREHGDTSRAEWLDQLTFRRIEQINAK 210
>UniRef50_P22543 Cluster: Phosphatidylinositol 3-kinase VPS34; n=5;
Saccharomycetales|Rep: Phosphatidylinositol 3-kinase
VPS34 - Saccharomyces cerevisiae (Baker's yeast)
Length = 875
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/217 (23%), Positives = 92/217 (42%), Gaps = 4/217 (1%)
Frame = +1
Query: 220 YVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSD-- 393
+ S LD +++KI +LEG + + + + +P L G SDL V+ Q+
Sbjct: 8 FCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSLQVFDKER 67
Query: 394 GEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTT 573
L LP+ T Y F W+ W+TLP+ L ++ L + +++ G ++ T
Sbjct: 68 NRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQIPFFNLET 127
Query: 574 ISIFG-KHGMLRQGMFDLRV-WPGVEGSEKTPGKAPDRGKEQMQRLAKLAKKHRNGHLPK 747
SIF K L++G L+ + ++ E ++ +E + K+ G +
Sbjct: 128 -SIFNLKDCTLKRGFESLKFRYDVIDHCEVV---TDNKDQENL-------NKYFQGEFTR 176
Query: 748 VXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXPXVXI 858
+ WLD +T ++ E L E P + +
Sbjct: 177 LPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLEL 213
>UniRef50_Q92213 Cluster: Phosphatidylinositol 3-kinase VPS34; n=4;
Saccharomycetales|Rep: Phosphatidylinositol 3-kinase
VPS34 - Candida albicans (Yeast)
Length = 1020
Score = 53.2 bits (122), Expect = 1e-05
Identities = 55/218 (25%), Positives = 95/218 (43%), Gaps = 12/218 (5%)
Frame = +1
Query: 229 SSSLDYKVEIKIGTLEGKRTKPEYDKL---LSDPML--KFSGLYQDGCSDLYVTCQILS- 390
S L + +K+ LE R L DP + K S +Y++ SDL+V ++
Sbjct: 23 SKDLKSPISVKVCYLECTRNNVSLVPLSTKFEDPTVFKKLSQIYKN--SDLFVEIRVYDG 80
Query: 391 -DGEPLALPVMTTYKAFTTRWN-WNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVG 564
+ ++ PV T+YKAF + WN+ + L + Y+ + +A L +I + K V G
Sbjct: 81 KNNNLISTPVRTSYKAFNNKGRTWNQQLKLNIDYNQISIDAYLKFSICEIIDT-KPSVFG 139
Query: 565 GTTISIFGKHGM-LRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQMQRLAKLAKK---HRN 732
+ +S+F LR G + V+ E P + + + L L K+ + N
Sbjct: 140 VSYLSLFSHDSSTLRSGSHKIPVF-----MEDDPQYSKNIQYGTLIGLTDLEKRLIDYEN 194
Query: 733 GHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYLMXEXP 846
G P++ WLD++ ++ K + YL E P
Sbjct: 195 GKYPRLNWLDKMVLPKVDATFLKTNNKDHDYYLYIELP 232
>UniRef50_A3LQL4 Cluster: 1-phosphatidylinositol 3-kinase; n=2;
Saccharomycetaceae|Rep: 1-phosphatidylinositol 3-kinase
- Pichia stipitis (Yeast)
Length = 1017
Score = 52.8 bits (121), Expect = 2e-05
Identities = 36/161 (22%), Positives = 73/161 (45%), Gaps = 3/161 (1%)
Frame = +1
Query: 358 SDLYVTCQILS--DGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYD 531
SDL++ I + + +PV TTYK+F + WN+++ + + ++ + ++ L + +Y+
Sbjct: 69 SDLFIKISIFDGKNNNLVTIPVQTTYKSFNNKRVWNQYLKMAINFNQVSIDSYLKIEVYE 128
Query: 532 CAGPGKVMVVGGTTISIFG-KHGMLRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQMQRLA 708
K + G +S+F K LR+G + ++ ++ T + L
Sbjct: 129 IVNT-KPKLFGVGYLSLFNRKSSRLRKGSQKIPIF-----TDPTTENIEYENIPGLTDLE 182
Query: 709 KLAKKHRNGHLPKVXWLDRLTXREIXMXNEKXXRXXNXMYL 831
K K+ +G ++ WLD+L + NE +YL
Sbjct: 183 KNLIKYEDGEFNRLGWLDKLVLPNVSSLNEPNKDHDYYLYL 223
>UniRef50_A5BD75 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 125
Score = 51.6 bits (118), Expect = 4e-05
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = +1
Query: 208 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 387
++F + S ++ V +I LEG P +S+ F ++ ++LYV C +
Sbjct: 4 NEFRFFLSCDINLPVTFRIERLEGNL--PSVKSSISE----FDYTTEERRAELYVECALF 57
Query: 388 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMT 522
DG P LP T ++ + WNE +TL Y DL ++ LA+T
Sbjct: 58 IDGAPFGLPTRTRLESTGPSYCWNELITLSTKYRDLTAHSQLALT 102
>UniRef50_Q01CW4 Cluster: Phosphatidylinositol 3-kinase; n=2;
cellular organisms|Rep: Phosphatidylinositol 3-kinase -
Ostreococcus tauri
Length = 845
Score = 51.2 bits (117), Expect = 5e-05
Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
Frame = +1
Query: 358 SDLYVTCQILSDGEPLALPVMTTYKAFTTRW-NWNEWVTLPVYYSDLPRNAILAMTIYDC 534
++++V+ +++++ EPL + TT A W E ++ P+ DLPR L + +
Sbjct: 41 NEVFVSARLIANEEPLTNEISTTAVAHIDGVAEWKEKLSFPITVRDLPRETQLELEVRSA 100
Query: 535 AG-PGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVEGSEKTP--GKAPDRGKEQMQRL 705
P V+ + ++IFG L QG + P E +K G +++RL
Sbjct: 101 RKFPSDVLC--RSRMAIFGDDNRLLQGSRCAMLTPSGETKKKHDYLGAKFMEQHAELERL 158
Query: 706 AKLAKKHRNGHLPKVXWLDRLTXREI 783
++ G+LP V WLD L I
Sbjct: 159 EGFLVQYEQGNLPSVNWLDNLVFSRI 184
>UniRef50_Q6CQA2 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=2; cellular organisms|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 862
Score = 48.4 bits (110), Expect = 4e-04
Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 3/184 (1%)
Frame = +1
Query: 220 YVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQILSD-- 393
+ S D + +KI LEG + + ++P L SD++V+ Q+
Sbjct: 8 FFVSHECDACLTVKIINLEGSSALLKQSEKYTEPDLSKRASNFIPNSDMFVSLQVFDGET 67
Query: 394 GEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTT 573
G L +PV T Y F W++W+TLP+ + L + L + +++ G + +
Sbjct: 68 GRNLTIPVYTKYVPFKNSRVWDQWLTLPIKINQLDMTSTLLIELWEYNGDTR-SIFAKLE 126
Query: 574 ISIFGKHG-MLRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQMQRLAKLAKKHRNGHLPKV 750
IF H L++G V+ + +EK D Q +A L + G L
Sbjct: 127 TQIFNSHDYSLKRGR---EVFKFTKDNEKRALPMKD------QNIA-LINDYHTGELKTS 176
Query: 751 XWLD 762
WLD
Sbjct: 177 QWLD 180
>UniRef50_UPI00004993D5 Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep:
phosphatidylinositol 3-kinase - Entamoeba histolytica
HM-1:IMSS
Length = 849
Score = 45.2 bits (102), Expect = 0.003
Identities = 30/128 (23%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
Frame = +1
Query: 358 SDLYVTCQILSDGEPLALPV-MTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDC 534
+ +++ ++S G P+A+ T + + ++ WN+ + P+ Y DL +A++ +Y C
Sbjct: 47 NQVWIGATLISGGVPIAIEEERTPTRDYISKAEWNDRIVFPIQYKDLSEDAVVVFRVY-C 105
Query: 535 AGPGKVMV-VGGTTISIFG--KHGMLRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQMQRL 705
K V VG + +F K +LR+G ++V P + + + ++++QRL
Sbjct: 106 YHVEKGYVPVGDAVLPLFSSDKGNVLRKGTKRVKVEPCKKSNCSISLDVEEYERQRLQRL 165
Query: 706 AKLAKKHR 729
K+ R
Sbjct: 166 ILDEKEER 173
>UniRef50_Q4SRM6 Cluster: Chromosome undetermined SCAF14516, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14516,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 305
Score = 44.4 bits (100), Expect = 0.006
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Frame = +1
Query: 454 WNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGT----------TISIFGKHGML 603
WNEW+T +Y +DLPR+A L ++I C+ G+ +GG +++F +L
Sbjct: 1 WNEWLTYDIYLADLPRSARLCLSI--CSVKGRKGAIGGRQEEHCPLAWGNVNLFDYKDIL 58
Query: 604 RQGMFDLRVWPGVEGSE 654
G L +WP G E
Sbjct: 59 VSGKVALSLWPVPHGLE 75
>UniRef50_Q57YM2 Cluster: Phosphatidylinositol 3-kinase, putative;
n=4; Trypanosoma|Rep: Phosphatidylinositol 3-kinase,
putative - Trypanosoma brucei
Length = 949
Score = 44.4 bits (100), Expect = 0.006
Identities = 33/149 (22%), Positives = 67/149 (44%), Gaps = 9/149 (6%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGP 543
L VT Q+ G P+ P++ + + EW+ P+ D+P +A++ +Y G
Sbjct: 113 LCVTLQMFHMGMPIT-PILQSSHTYGCHQRLEEWIIFPIAIQDIPLDALVHCHVYAPHG- 170
Query: 544 GKVMVVGGTTISIFGKHGMLRQG--MFDLRVW--PGVEGSEKTPGKAPDRGKEQMQRLAK 711
+VG T+ F G L+ G ++L+ G E ++ + + K R+
Sbjct: 171 ----LVGRTSFHPFTACGELKTGRRRYELQAGTAAGTERADHDDSDSVNGNKRAPSRMGM 226
Query: 712 -----LAKKHRNGHLPKVXWLDRLTXREI 783
+ + R G +P++ W+D++ R++
Sbjct: 227 NPQELMLRDLRRGLVPQIPWMDKMIKRQV 255
>UniRef50_P42336 Cluster: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit alpha isoform; n=38;
root|Rep: Phosphatidylinositol-4,5-bisphosphate 3-kinase
catalytic subunit alpha isoform - Homo sapiens (Human)
Length = 1068
Score = 44.4 bits (100), Expect = 0.006
Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG- 540
+YV I GEPL V T + + WNEW+ +Y DLPR A L ++I G
Sbjct: 354 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGR 412
Query: 541 ---PGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVEGSE 654
+ + I++F L G L +WP G E
Sbjct: 413 KGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLE 453
>UniRef50_A2DJM8 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=4; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1134
Score = 43.2 bits (97), Expect = 0.014
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Frame = +1
Query: 382 ILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPG-KVMV 558
I+ L PVMT T +WNE +T+ + LPR+A +A+T+Y+ G K
Sbjct: 469 IIHGSNELGAPVMTRPALGGTSVSWNEMLTVSLQIQQLPRSARVAITLYNYEKIGSKGSA 528
Query: 559 VGGTTISIFGKHGMLRQGMFDLRVWPG 639
+ I +F G G+ +W G
Sbjct: 529 IATINIPVFNFDGWYNSGVNFRSMWNG 555
>UniRef50_A0E0Q4 Cluster: Chromosome undetermined scaffold_72, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_72,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 871
Score = 42.7 bits (96), Expect = 0.019
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 6/97 (6%)
Frame = +1
Query: 424 TYKAFTTR-WNWNEWVTLPVYYSDLPRNAILAMTIYDCAGP-GKVMVVGGTTISIFGKHG 597
T+KAF+ E + DL N+++A++IY + +G TT +F ++
Sbjct: 65 TFKAFSRHSLQKQETIFFNSNIKDLSYNSLIALSIYSTQQKYEEAKPLGSTTFPLFDENL 124
Query: 598 MLRQGMFDLRVWPGVEG----SEKTPGKAPDRGKEQM 696
LR+G +L +WP + + KTPG DR + +
Sbjct: 125 KLREGKINLLIWPNTQPDTSFNSKTPGLVKDRNIQDL 161
>UniRef50_UPI00006CFDD2 Cluster: Phosphatidylinositol 3- and
4-kinase family protein; n=1; Tetrahymena thermophila
SB210|Rep: Phosphatidylinositol 3- and 4-kinase family
protein - Tetrahymena thermophila SB210
Length = 891
Score = 41.9 bits (94), Expect = 0.033
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +1
Query: 370 VTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGK 549
VT Q++ + + + P T F R + + + Y DL N+I+A+T++ C+ K
Sbjct: 53 VTAQLVVNEKKIQ-PAQQTL--FIDRMLFEQNIIFNYKYKDLSYNSIIAITLW-CSQKNK 108
Query: 550 --VMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
+G TTIS+F LRQG + L +WP
Sbjct: 109 DEKKPLGCTTISLFDDQFRLRQGKYHLYIWP 139
>UniRef50_Q241V8 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1249
Score = 41.9 bits (94), Expect = 0.033
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Frame = +1
Query: 355 CSDLYVTCQI-LSDGEPLALPVMTTYKAFTTRWNWNEWVTLP-VYYSDLPRNAILAMTIY 528
C+ V+ ++ L G V T + F +NEWVT + S +P A + M I
Sbjct: 539 CTPYLVSLKVMLFHGSNCLRTVETKKQPFCKSIRFNEWVTFDNLKISQIPLEARICMNII 598
Query: 529 -DCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
+ ++G T+ S+F + RQG+ L VWP
Sbjct: 599 LHSDDQNEHQIIGSTSFSLFDQDDKYRQGLNALNVWP 635
>UniRef50_P54675 Cluster: Phosphatidylinositol 3-kinase 3; n=5;
Eukaryota|Rep: Phosphatidylinositol 3-kinase 3 -
Dictyostelium discoideum (Slime mold)
Length = 1585
Score = 41.5 bits (93), Expect = 0.043
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGP 543
L++ + GE LA + +F WNEWV +P+ S++P A + + + +
Sbjct: 808 LFIEAAVYFGGELLATQ-SSKLVSFQDTVVWNEWVNIPLAVSNIPNGARMCLGL-NARYR 865
Query: 544 GKVMVVGGTTISIFGKHGMLRQ-GMFDLRVWPG 639
G + +G +F G+L F L +WPG
Sbjct: 866 GDIFNIGWVGHRLFDSKGILNTFAPFSLLLWPG 898
>UniRef50_Q4T9W9 Cluster: Chromosome undetermined SCAF7485, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7485,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1841
Score = 41.1 bits (92), Expect = 0.057
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Frame = +1
Query: 367 YVTCQILSDGEPLALPVMT----TYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 528
Y+TC + +G+ L P+ + TYK F W+E ++ PV + LP A+L +T++
Sbjct: 739 YLTCSLTHNGKNLFKPIQSKKVGTYKNFFYHIKWDELISFPVAVAILPLEALLTLTLF 796
>UniRef50_Q22H25 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1559
Score = 38.7 bits (86), Expect = 0.30
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLP-VYYSDLPRNAILAMTI--YDC 534
+ V +++ LA+ T F+ W+EW+ P + S LP + + I Y
Sbjct: 850 IQVQVKLMYGNRALAVKKETQKIPFSRSPRWDEWIKFPLIKISQLPLESRICFDIIVYSV 909
Query: 535 AGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
G ++G T IF + QG+ L +WP
Sbjct: 910 TGLDS-QIIGSTNFYIFDQFCKFTQGISPLNIWP 942
>UniRef50_Q2Y888 Cluster: Putative uncharacterized protein; n=1;
Nitrosospira multiformis ATCC 25196|Rep: Putative
uncharacterized protein - Nitrosospira multiformis
(strain ATCC 25196 / NCIMB 11849)
Length = 1002
Score = 38.3 bits (85), Expect = 0.40
Identities = 18/41 (43%), Positives = 24/41 (58%)
Frame = -1
Query: 678 VRSLPRSLLAALNPGPHSQIEHPLSQHAVLPEYRYGRATDH 556
+R PR LLA +N P Q+EH L +HA +P G A D+
Sbjct: 368 IRLAPRKLLAIVNGTPAQQMEHDLFRHAAMPLEYLGLALDY 408
>UniRef50_A0DLV0 Cluster: Chromosome undetermined scaffold_556,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_556,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1225
Score = 37.9 bits (84), Expect = 0.53
Identities = 17/50 (34%), Positives = 25/50 (50%)
Frame = +1
Query: 487 SDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
S LP L I + G+ ++G T +F ++G L+QG L VWP
Sbjct: 506 SQLPMELRLCFNIVLHSSNGEEQIIGSTITELFDENGKLKQGRLHLNVWP 555
>UniRef50_O00443 Cluster: Phosphatidylinositol-4-phosphate 3-kinase
C2 domain-containing alpha polypeptide; n=28;
Euteleostomi|Rep: Phosphatidylinositol-4-phosphate
3-kinase C2 domain-containing alpha polypeptide - Homo
sapiens (Human)
Length = 1686
Score = 37.9 bits (84), Expect = 0.53
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Frame = +1
Query: 367 YVTCQILSDGEPLALPVMT----TYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 528
Y+ C + +G+ L P+ + TYK F W+E + P+ S LP ++L +T++
Sbjct: 708 YLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLF 765
>UniRef50_A2FAC3 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=6; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 817
Score = 37.5 bits (83), Expect = 0.70
Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Frame = +1
Query: 448 WNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGM-LRQGMFDL 624
+ W++ + +P+ YS+LP ++I + C K ++G + + +F + LR G F L
Sbjct: 116 FTWDQALVIPILYSELPHDSIAKFKFFACLFQSKPTLIGESEVRLFTRRNRHLRLGPFAL 175
>UniRef50_Q1L913 Cluster: Novel protein similar to vertebrate
phosphoinositide-3-kinase, class 2, alpha polypeptide;
n=3; Danio rerio|Rep: Novel protein similar to
vertebrate phosphoinositide-3-kinase, class 2, alpha
polypeptide - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1725
Score = 37.1 bits (82), Expect = 0.93
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Frame = +1
Query: 367 YVTCQILSDGEPLALPVMT----TYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 528
Y+ C + + L PV + TYK+F W+E + P+ S LP A+L++++Y
Sbjct: 727 YLMCALTHNNRNLFKPVQSKKVGTYKSFFYHIKWDELINFPISVSLLPLEAMLSLSLY 784
>UniRef50_A7RRA6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1310
Score = 37.1 bits (82), Expect = 0.93
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 10/91 (10%)
Frame = +1
Query: 394 GEPLALPVMTTYKAFTTR-----WNWNEWVTLPVYYSDLPRNAILAMTIYDC-----AGP 543
G L P+ TT ++ TR W +W+ + LPR + L +T+Y P
Sbjct: 345 GGCLLCPIETTTQSKLTRKFSELLQWGDWLKFDIPVKRLPRESRLCLTLYGTKPSSKGNP 404
Query: 544 GKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
+G + +F +G+L G L +WP
Sbjct: 405 SARSALGWVALQLFNFNGVLLTGTQILGLWP 435
>UniRef50_A0D2V1 Cluster: Chromosome undetermined scaffold_35, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_35,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1447
Score = 37.1 bits (82), Expect = 0.93
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +1
Query: 466 VTLP-VYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
+T P + S LP+ A L I + G+ ++G TT+ IF + R M L VWP
Sbjct: 560 ITFPGIKISQLPQEARLCFNIIAHSAIGQQQIIGCTTMYIFSEEKRFRAHMNQLNVWP 617
>UniRef50_UPI0000F21165 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1069
Score = 36.7 bits (81), Expect = 1.2
Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 15/113 (13%)
Frame = +1
Query: 364 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG- 540
+YV I+ G+ + +T K FT WN W+ + D+P+ A L +TI
Sbjct: 361 VYVEATIIY-GKKTISSICSTPKEFTDEVLWNTWLEFDILIRDIPQGAKLGLTINATEAA 419
Query: 541 --------------PGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVEGSEK 657
GK+ V+ + + +L QG L +WP E E+
Sbjct: 420 KETKSSSSKVPDHHKGKLQVLYFVNLQLIDHRSLLSQGPHTLNMWPFPEWDEE 472
>UniRef50_Q237I3 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1200
Score = 35.9 bits (79), Expect = 2.1
Identities = 20/87 (22%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 382 ILSDGEPLALPVMTTYKAFTTRWNWNEWVTLP-VYYSDLPRNAILAMTIYDCA-GPGKVM 555
I+ +G V T + +N+W++ + S LP + L + A
Sbjct: 454 IIMNGSTCIKSVETKRVPYGNTCKFNQWISFNNIKVSQLPLESRLCFNLKAYAQNSNDYQ 513
Query: 556 VVGGTTISIFGKHGMLRQGMFDLRVWP 636
++G +T+ IF + +QG+ + VWP
Sbjct: 514 IIGSSTLPIFNSQELFQQGLNAINVWP 540
>UniRef50_A7B576 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 308
Score = 35.5 bits (78), Expect = 2.8
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +1
Query: 349 DGCSDLYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAI 510
DGC+DL + +I+ PL+ PV+ + F +WN + +Y SD + I
Sbjct: 191 DGCNDLQIFMKIIL---PLSKPVLASVSLFYAVTHWNSYFNAMMYISDSKKEVI 241
>UniRef50_P48736 Cluster: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit gamma isoform; n=30;
Euteleostomi|Rep: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit gamma isoform - Homo sapiens
(Human)
Length = 1102
Score = 35.5 bits (78), Expect = 2.8
Identities = 31/142 (21%), Positives = 53/142 (37%), Gaps = 16/142 (11%)
Frame = +1
Query: 385 LSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGP------- 543
+ G+ + T+ K FT WN W+ + DLP+ A+L + IY P
Sbjct: 387 IQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKAS 446
Query: 544 ---------GKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVEGSEKTPGKAPDRGKEQM 696
GKV ++ + + +LR+G + L +W + GK D+G
Sbjct: 447 AESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMW-------QISGKGEDQGSFNA 499
Query: 697 QRLAKLAKKHRNGHLPKVXWLD 762
+L + + LD
Sbjct: 500 DKLTSATNPDKENSMSISILLD 521
>UniRef50_O00750 Cluster: Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing beta polypeptide; n=35;
Deuterostomia|Rep: Phosphatidylinositol-4-phosphate
3-kinase C2 domain-containing beta polypeptide - Homo
sapiens (Human)
Length = 1634
Score = 35.5 bits (78), Expect = 2.8
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 16/122 (13%)
Frame = +1
Query: 361 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 528
D Y++C + G+ L P+ T F+ W++ + PV + LPR +L T+Y
Sbjct: 651 DFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 710
Query: 529 --DCAGPGKVM----------VVGGTTISIFGKHGMLRQGMFDLRVWPGVEGSEKTPGKA 672
PG +G T +F +L G L +WP + + A
Sbjct: 711 ALPIPPPGSSSEANKQRRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENPSARWSA 770
Query: 673 PD 678
P+
Sbjct: 771 PN 772
>UniRef50_UPI0000498E9A Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep:
phosphatidylinositol 3-kinase - Entamoeba histolytica
HM-1:IMSS
Length = 1115
Score = 35.1 bits (77), Expect = 3.7
Identities = 19/54 (35%), Positives = 26/54 (48%)
Frame = +1
Query: 484 YSDLPRNAILAMTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWPGVE 645
YS LP L +T+Y GK +V+G +F L G +LR+WP E
Sbjct: 487 YSMLPLETRLGITLY-AIRKGKKVVIGFVNTPLFDFQNFLLSGYVNLRLWPDEE 539
>UniRef50_Q9KB22 Cluster: ABC transporter; n=9; Firmicutes|Rep: ABC
transporter - Bacillus halodurans
Length = 308
Score = 35.1 bits (77), Expect = 3.7
Identities = 17/62 (27%), Positives = 25/62 (40%)
Frame = +1
Query: 400 PLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGGTTIS 579
PL LPV+ T F WN W + +Y S+ P + L + + G+ S
Sbjct: 197 PLCLPVIATVSLFVAVGQWNSWFDVFIYNSNKPELSTLQYELMKILQNSNASMSSGSAAS 256
Query: 580 IF 585
F
Sbjct: 257 AF 258
>UniRef50_A4XN07 Cluster: Binding-protein-dependent transport
systems inner membrane component; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Binding-protein-dependent transport systems inner
membrane component - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 294
Score = 35.1 bits (77), Expect = 3.7
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = +1
Query: 349 DGCSDLYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSD 492
DG S++Y+ +I+ PL+ P + T F WNEW +Y +D
Sbjct: 176 DGASEVYILWKIIL---PLSKPAIATLSLFYALGYWNEWFKCVLYITD 220
>UniRef50_A0DT78 Cluster: Chromosome undetermined scaffold_62, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_62,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1176
Score = 35.1 bits (77), Expect = 3.7
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Frame = +1
Query: 478 VYYSDLPRNAILA--MTIYDCAGPGKVMVVGGTTISIFGKHGMLRQGMFDLRVWP 636
+ YS LP L + IY C G ++ VG T++ +F ++ +QG+ L +WP
Sbjct: 408 IKYSMLPLEVKLCFRVLIYSCHGESQI--VGSTSMYLFDQNSKFKQGLQTLNLWP 460
>UniRef50_Q2T981 Cluster: Putative uncharacterized protein; n=1;
Burkholderia thailandensis E264|Rep: Putative
uncharacterized protein - Burkholderia thailandensis
(strain E264 / ATCC 700388 / DSM 13276 /CIP 106301)
Length = 271
Score = 34.7 bits (76), Expect = 4.9
Identities = 18/54 (33%), Positives = 26/54 (48%)
Frame = -1
Query: 723 FLGELRKSLHLFFAAVRSLPRSLLAALNPGPHSQIEHPLSQHAVLPEYRYGRAT 562
F+ + K L +F A ++ PR +LAA GP + P H R+GR T
Sbjct: 102 FVSKTGKHLSVFDAVIQEGPRQVLAAQATGPFLYVRLPAGCHTASARDRHGRET 155
>UniRef50_Q3S4D5 Cluster: LysR-like regular protein; n=1;
Polaromonas naphthalenivorans CJ2|Rep: LysR-like regular
protein - Polaromonas naphthalenivorans (strain CJ2)
Length = 301
Score = 34.7 bits (76), Expect = 4.9
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = -3
Query: 604 SACRASRISIWSCHRPPSLYRGRHSRR 524
+ CRA R +IWSC+ PPS RHS +
Sbjct: 248 TVCRAMRSAIWSCYVPPSGPPARHSNQ 274
>UniRef50_UPI0000F2E101 Cluster: PREDICTED: similar to AFF3 protein;
n=1; Monodelphis domestica|Rep: PREDICTED: similar to
AFF3 protein - Monodelphis domestica
Length = 1282
Score = 34.3 bits (75), Expect = 6.5
Identities = 16/42 (38%), Positives = 19/42 (45%)
Frame = -3
Query: 679 GPEPSPESSRCPQPRATLADRTSPVSACRASRISIWSCHRPP 554
GP P P S C +P T+ RAS +CHRPP
Sbjct: 593 GPPPPPRRSACKKPPRRTTTTTTTTITERASAGESANCHRPP 634
>UniRef50_UPI0000EB073C Cluster: Rho GTPase-activating protein 22
(Rho-type GTPase-activating protein 22).; n=1; Canis
lupus familiaris|Rep: Rho GTPase-activating protein 22
(Rho-type GTPase-activating protein 22). - Canis
familiaris
Length = 651
Score = 34.3 bits (75), Expect = 6.5
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = -3
Query: 757 ASXP*ANVRFCVSWRASQVAASVLCRGPEPSPESSRCPQPRATLADRTSPVSACRAS-RI 581
A+ P V+ SW++S + P+ S+R PQ RA T+P +ACRAS R+
Sbjct: 308 ATSPGKRVQTLPSWKSSSRQSGSRPGSPKGGASSAREPQGRACTQSSTTP-AACRASQRV 366
Query: 580 SIWSC 566
+ +C
Sbjct: 367 TASAC 371
>UniRef50_Q14M65 Cluster: Hypothetical oligopeptide abc transporter
permease component transmembrane protein; n=1;
Spiroplasma citri|Rep: Hypothetical oligopeptide abc
transporter permease component transmembrane protein -
Spiroplasma citri
Length = 414
Score = 34.3 bits (75), Expect = 6.5
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Frame = +1
Query: 502 NAILAMTIYDCAGPGKVMVVGGTTISI--FGKHGMLRQGMFDLRVWP 636
N I A +I A P V+VVG ISI F HG+ G FD + WP
Sbjct: 236 NTINAGSIIFLAIPPVVLVVGIYLISINFFYAHGLFSSGTFDTKFWP 282
>UniRef50_Q8WXI7 Cluster: Mucin-16; n=23; cellular organisms|Rep:
Mucin-16 - Homo sapiens (Human)
Length = 22152
Score = 34.3 bits (75), Expect = 6.5
Identities = 13/34 (38%), Positives = 22/34 (64%)
Frame = -2
Query: 635 GHTRRSNIPCLSMPCFPNIDMVVPPTTITLPGPA 534
G T+RS++P S+P P +D+ T ++ PGP+
Sbjct: 21240 GFTQRSSVPTTSIPGTPTVDLGTSGTPVSKPGPS 21273
>UniRef50_Q1FGG3 Cluster: Binding-protein-dependent transport
systems inner membrane component precursor; n=1;
Clostridium phytofermentans ISDg|Rep:
Binding-protein-dependent transport systems inner
membrane component precursor - Clostridium
phytofermentans ISDg
Length = 277
Score = 33.9 bits (74), Expect = 8.6
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = +1
Query: 349 DGCSDLYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAI 510
DGC + +I+ PLA P + T F+ W+WN+++ +Y S + + +
Sbjct: 176 DGCDHFRIYWRIIF---PLAKPAIATMALFSFTWSWNDYMGPYLYISTMDKQML 226
>UniRef50_A0H454 Cluster: Binding-protein-dependent transport
systems inner membrane component; n=3; Bacteria|Rep:
Binding-protein-dependent transport systems inner
membrane component - Chloroflexus aggregans DSM 9485
Length = 306
Score = 33.9 bits (74), Expect = 8.6
Identities = 17/81 (20%), Positives = 35/81 (43%)
Frame = +1
Query: 298 YDKLLSDPMLKFSGLYQDGCSDLYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLP 477
Y+ + + P F + DG S + +++ PL+ P + ++ F W WN+ +
Sbjct: 187 YNYISTVPRDIFESAFLDGASHFTIFTRLIL---PLSTPALASFAIFQFLWTWNDLLVAL 243
Query: 478 VYYSDLPRNAILAMTIYDCAG 540
V+ PR ++ + G
Sbjct: 244 VFLGAEPRVQVVTQRLLGLLG 264
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 822,333,207
Number of Sequences: 1657284
Number of extensions: 18464725
Number of successful extensions: 57104
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 51933
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 56713
length of database: 575,637,011
effective HSP length: 103
effective length of database: 404,936,759
effective search space used: 123910648254
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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