Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP23_F_A03
(1247 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain ... 55 5e-07
BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain ... 55 5e-07
AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein. 55 5e-07
BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain ... 52 3e-06
AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin li... 52 3e-06
AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein. 52 3e-06
AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligas... 46 4e-04
AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMU... 46 4e-04
AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2 pro... 46 4e-04
AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein. 46 4e-04
BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiqui... 39 0.044
BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiqui... 39 0.044
BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein. 39 0.044
AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smu... 39 0.044
AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMU... 39 0.044
AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMU... 39 0.044
U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein. 36 0.41
BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein. 36 0.41
BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3... 36 0.41
AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens ... 36 0.41
BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein. 35 0.54
AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiqui... 35 0.54
AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiqui... 35 0.54
AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiqui... 35 0.54
AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiqui... 35 0.54
AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligas... 35 0.54
AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting ... 35 0.54
AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiqui... 35 0.54
AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligas... 35 0.54
U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein. 33 1.6
BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3... 33 1.6
BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein. 33 1.6
AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiqui... 33 1.6
AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing pr... 33 1.6
D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein. 32 5.0
AY550969-1|AAT52215.1| 900|Homo sapiens cell proliferation-indu... 32 5.0
>BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G++ E ELKPGG ++ VTE+NKK QTE LVR
Sbjct: 1369 LDLTFTVNEEVF-GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVR 1427
Query: 246 GFHEVASSPFFS 281
GF+EV + S
Sbjct: 1428 GFYEVVDARLVS 1439
>BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G++ E ELKPGG ++ VTE+NKK QTE LVR
Sbjct: 1369 LDLTFTVNEEVF-GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVR 1427
Query: 246 GFHEVASSPFFS 281
GF+EV + S
Sbjct: 1428 GFYEVVDARLVS 1439
>AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein.
Length = 1581
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G++ E ELKPGG ++ VTE+NKK QTE LVR
Sbjct: 1378 LDLTFTVNEEVF-GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVR 1436
Query: 246 GFHEVASSPFFS 281
GF+EV + S
Sbjct: 1437 GFYEVVDARLVS 1448
>BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 1 protein.
Length = 1606
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/72 (43%), Positives = 38/72 (52%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G+V E ELK GG + VTE+NKK QTE LVR
Sbjct: 1403 LDLTFTVNEEVF-GQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVR 1461
Query: 246 GFHEVASSPFFS 281
GF+EV S S
Sbjct: 1462 GFYEVVDSRLVS 1473
>AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin ligase
1 protein.
Length = 1585
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/72 (43%), Positives = 38/72 (52%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G+V E ELK GG + VTE+NKK QTE LVR
Sbjct: 1382 LDLTFTVNEEVF-GQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVR 1440
Query: 246 GFHEVASSPFFS 281
GF+EV S S
Sbjct: 1441 GFYEVVDSRLVS 1452
>AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein.
Length = 1614
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/72 (43%), Positives = 38/72 (52%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V+E + G+V E ELK GG + VTE+NKK QTE LVR
Sbjct: 1411 LDLTFTVNEEVF-GQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVR 1469
Query: 246 GFHEVASSPFFS 281
GF+EV S S
Sbjct: 1470 GFYEVVDSRLVS 1481
>AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligase
Smurf1-beta protein.
Length = 757
Score = 45.6 bits (103), Expect = 4e-04
Identities = 28/73 (38%), Positives = 35/73 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A GR+L+ ELKP GR+V VTE NKK Q L +
Sbjct: 551 LDHTFCV-EHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQK 609
Query: 246 GFHEVASSPFFSP 284
GF+E+ P
Sbjct: 610 GFNELIPQHLLKP 622
>AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMURF1
protein.
Length = 722
Score = 45.6 bits (103), Expect = 4e-04
Identities = 28/73 (38%), Positives = 35/73 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A GR+L+ ELKP GR+V VTE NKK Q L +
Sbjct: 516 LDHTFCV-EHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQK 574
Query: 246 GFHEVASSPFFSP 284
GF+E+ P
Sbjct: 575 GFNELIPQHLLKP 587
>AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2
protein.
Length = 712
Score = 45.6 bits (103), Expect = 4e-04
Identities = 28/73 (38%), Positives = 35/73 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A GR+L+ ELKP GR+V VTE NKK Q L +
Sbjct: 506 LDHTFCV-EHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQK 564
Query: 246 GFHEVASSPFFSP 284
GF+E+ P
Sbjct: 565 GFNELIPQHLLKP 577
>AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein.
Length = 859
Score = 45.6 bits (103), Expect = 4e-04
Identities = 28/73 (38%), Positives = 35/73 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A GR+L+ ELKP GR+V VTE NKK Q L +
Sbjct: 653 LDHTFCV-EHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQK 711
Query: 246 GFHEVASSPFFSP 284
GF+E+ P
Sbjct: 712 GFNELIPQHLLKP 724
>BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 545 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 603
Query: 246 GFHEV 260
GF+EV
Sbjct: 604 GFNEV 608
>BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 545 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 603
Query: 246 GFHEV 260
GF+EV
Sbjct: 604 GFNEV 608
>BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein.
Length = 288
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 85 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 143
Query: 246 GFHEV 260
GF+EV
Sbjct: 144 GFNEV 148
>AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smurf2
protein.
Length = 748
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 545 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 603
Query: 246 GFHEV 260
GF+EV
Sbjct: 604 GFNEV 608
>AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMURF2
protein.
Length = 748
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 545 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 603
Query: 246 GFHEV 260
GF+EV
Sbjct: 604 GFNEV 608
>AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMURF2
protein.
Length = 748
Score = 38.7 bits (86), Expect = 0.044
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
L+ TF V E A G +++ ELKP G+ + V E NKK Q L +
Sbjct: 545 LDHTFCV-EHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQK 603
Query: 246 GFHEV 260
GF+EV
Sbjct: 604 GFNEV 608
>U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein.
Length = 870
Score = 35.5 bits (78), Expect = 0.41
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +3
Query: 105 GRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVRGFHEVA 263
G+V ELK GG + VTE NK+ QT+ + GF+EVA
Sbjct: 680 GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVA 732
>BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein.
Length = 870
Score = 35.5 bits (78), Expect = 0.41
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +3
Query: 105 GRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVRGFHEVA 263
G+V ELK GG + VTE NK+ QT+ + GF+EVA
Sbjct: 680 GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVA 732
>BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3
ubiquitin protein ligase 2 protein.
Length = 870
Score = 35.5 bits (78), Expect = 0.41
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +3
Query: 105 GRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVRGFHEVA 263
G+V ELK GG + VTE NK+ QT+ + GF+EVA
Sbjct: 680 GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVA 732
>AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens
cDNA FLJ44359 fis, clone TRACH3007479, highly similar
to Homo sapiens Nedd-4-like ubiquitin-protein ligase
(WWP2). ).
Length = 343
Score = 35.5 bits (78), Expect = 0.41
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +3
Query: 105 GRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVRGFHEVA 263
G+V ELK GG + VTE NK+ QT+ + GF+EVA
Sbjct: 241 GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVA 293
>BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein.
Length = 903
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 701 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 759
Query: 246 GFHEV 260
GF+E+
Sbjct: 760 GFNEI 764
>AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 701 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 759
Query: 246 GFHEV 260
GF+E+
Sbjct: 760 GFNEI 764
>AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 660 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 718
Query: 246 GFHEV 260
GF+E+
Sbjct: 719 GFNEI 723
>AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 701 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 759
Query: 246 GFHEV 260
GF+E+
Sbjct: 760 GFNEI 764
>AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 660 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 718
Query: 246 GFHEV 260
GF+E+
Sbjct: 719 GFNEI 723
>AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligase
ITCH protein.
Length = 862
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 660 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 718
Query: 246 GFHEV 260
GF+E+
Sbjct: 719 GFNEI 723
>AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting
protein 4 protein.
Length = 739
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 537 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 595
Query: 246 GFHEV 260
GF+E+
Sbjct: 596 GFNEI 600
>AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiquitin
protein ligase variant protein.
Length = 605
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 403 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 461
Query: 246 GFHEV 260
GF+E+
Sbjct: 462 GFNEI 466
>AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligase
Itch protein.
Length = 862
Score = 35.1 bits (77), Expect = 0.54
Identities = 19/65 (29%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + + G + +LKP G ++ VTE NK+ QT+
Sbjct: 660 LEMYFSVDKEIL-GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE 718
Query: 246 GFHEV 260
GF+E+
Sbjct: 719 GFNEI 723
>U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein.
Length = 684
Score = 33.5 bits (73), Expect = 1.6
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + G+V +LK GG ++ VTE NK QT+ +
Sbjct: 531 LEMYFSVDMEIL-GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLD 589
Query: 246 GFHEV 260
GF+EV
Sbjct: 590 GFNEV 594
>BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3
ubiquitin protein ligase 1 protein.
Length = 922
Score = 33.5 bits (73), Expect = 1.6
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + G+V +LK GG ++ VTE NK QT+ +
Sbjct: 720 LEMYFSVDMEIL-GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLD 778
Query: 246 GFHEV 260
GF+EV
Sbjct: 779 GFNEV 783
>BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein.
Length = 300
Score = 33.5 bits (73), Expect = 1.6
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + G+V +LK GG ++ VTE NK QT+ +
Sbjct: 98 LEMYFSVDMEIL-GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLD 156
Query: 246 GFHEV 260
GF+EV
Sbjct: 157 GFNEV 161
>AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiquitin
ligase 1 protein.
Length = 922
Score = 33.5 bits (73), Expect = 1.6
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + G+V +LK GG ++ VTE NK QT+ +
Sbjct: 720 LEMYFSVDMEIL-GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLD 778
Query: 246 GFHEV 260
GF+EV
Sbjct: 779 GFNEV 783
>AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing
protein 1 protein.
Length = 922
Score = 33.5 bits (73), Expect = 1.6
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +3
Query: 66 LEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKKXXXXXXXXXXXXXXXXXQTEWLVR 245
LE F+V + G+V +LK GG ++ VTE NK QT+ +
Sbjct: 720 LEMYFSVDMEIL-GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLD 778
Query: 246 GFHEV 260
GF+EV
Sbjct: 779 GFNEV 783
>D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein.
Length = 927
Score = 31.9 bits (69), Expect = 5.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 60 SSLEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKK 173
+ L+ F + E L G+ + ELK GG ++ VT +NKK
Sbjct: 721 TELDLRFIIDEELF-GQTHQHELKNGGSEIVVTNKNKK 757
>AY550969-1|AAT52215.1| 900|Homo sapiens cell
proliferation-inducing protein 53 protein.
Length = 900
Score = 31.9 bits (69), Expect = 5.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 60 SSLEXTFAVSERLADGRVLEXELKPGGRDVAVTERNKK 173
+ L+ F + E L G+ + ELK GG ++ VT +NKK
Sbjct: 694 TELDLRFIIDEELF-GQTHQHELKNGGSEIVVTNKNKK 730
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,181,124
Number of Sequences: 237096
Number of extensions: 2608217
Number of successful extensions: 10285
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 9925
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10273
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17779932290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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