Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP21_F_D11
(881 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC015191-1|AAH15191.1| 322|Homo sapiens PDZ binding kinase prot... 176 8e-44
AF189722-1|AAF69107.1| 322|Homo sapiens PDZ-binding kinase prot... 176 8e-44
AB027250-1|BAA99577.1| 322|Homo sapiens MPAKK-like protein kina... 176 8e-44
AB027249-1|BAA99576.1| 322|Homo sapiens MAPKK like protein kina... 176 8e-44
AK027291-1|BAB55019.1| 322|Homo sapiens protein ( Homo sapiens ... 174 4e-43
AF237709-1|AAF71521.1| 322|Homo sapiens spermatogenesis-related... 174 4e-43
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 69 3e-11
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 69 3e-11
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 64 6e-10
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 64 6e-10
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 63 1e-09
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 63 1e-09
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 63 1e-09
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 63 1e-09
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 63 1e-09
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 62 3e-09
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 62 3e-09
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 61 5e-09
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 61 5e-09
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 61 5e-09
CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein. 60 8e-09
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 60 8e-09
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 60 1e-08
U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein. 60 1e-08
U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein. 60 1e-08
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 60 1e-08
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 60 1e-08
L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein. 60 1e-08
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 60 1e-08
D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b prot... 60 1e-08
CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein. 60 1e-08
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 60 1e-08
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 60 1e-08
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 60 1e-08
BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated prote... 60 1e-08
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 60 1e-08
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 60 1e-08
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 60 1e-08
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 60 1e-08
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 60 1e-08
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 60 1e-08
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 60 1e-08
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 60 1e-08
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 60 1e-08
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 60 1e-08
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 60 1e-08
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 59 2e-08
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 59 2e-08
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 59 2e-08
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 59 2e-08
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 59 2e-08
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 59 2e-08
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 59 2e-08
AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated prote... 59 2e-08
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 59 2e-08
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 58 4e-08
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 58 4e-08
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 58 4e-08
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 58 4e-08
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 58 4e-08
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 58 4e-08
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 58 4e-08
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 58 4e-08
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 58 6e-08
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 58 6e-08
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 57 7e-08
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 57 1e-07
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 57 1e-07
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 57 1e-07
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 57 1e-07
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 57 1e-07
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 57 1e-07
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 57 1e-07
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 57 1e-07
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 57 1e-07
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 57 1e-07
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 57 1e-07
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 57 1e-07
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 56 2e-07
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 56 2e-07
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 56 2e-07
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 56 2e-07
X96757-1|CAA65532.1| 334|Homo sapiens MAP kinase kinase protein. 56 2e-07
U49732-1|AAB05035.1| 334|Homo sapiens MAP kinase kinase MEK6 pr... 56 2e-07
U39657-1|AAC50389.1| 334|Homo sapiens MAP kinase kinase 6 protein. 56 2e-07
U39656-1|AAC50388.1| 334|Homo sapiens MAP kinase kinase 6 protein. 56 2e-07
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 56 2e-07
D87905-1|BAA13496.1| 334|Homo sapiens mitogen-activated protein... 56 2e-07
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 56 2e-07
BC012009-1|AAH12009.1| 334|Homo sapiens mitogen-activated prote... 56 2e-07
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 56 2e-07
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 55 3e-07
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 55 3e-07
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 55 3e-07
U39065-1|AAB03705.1| 334|Homo sapiens MAP kinase kinase 6b prot... 55 3e-07
U39064-1|AAB03708.1| 278|Homo sapiens MAP kinase kinase 6 protein. 55 3e-07
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 55 3e-07
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 55 3e-07
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 55 3e-07
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 55 3e-07
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 55 3e-07
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 55 3e-07
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 55 3e-07
Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine pro... 55 4e-07
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 55 4e-07
DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated prote... 55 4e-07
BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated prote... 55 4e-07
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 54 5e-07
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 54 5e-07
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 54 5e-07
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 54 5e-07
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 54 5e-07
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 5e-07
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 5e-07
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 54 5e-07
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 54 5e-07
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 54 5e-07
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 54 5e-07
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 54 7e-07
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 54 7e-07
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 53 1e-06
BC067760-1|AAH67760.1| 380|Homo sapiens LOC407835 protein protein. 53 1e-06
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 53 1e-06
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 53 1e-06
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 53 1e-06
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 53 1e-06
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 53 2e-06
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 53 2e-06
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 53 2e-06
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 53 2e-06
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 53 2e-06
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 53 2e-06
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 53 2e-06
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 53 2e-06
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 53 2e-06
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 53 2e-06
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 53 2e-06
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 53 2e-06
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 53 2e-06
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 53 2e-06
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 53 2e-06
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 53 2e-06
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 53 2e-06
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 53 2e-06
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 53 2e-06
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 53 2e-06
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 53 2e-06
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 53 2e-06
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 53 2e-06
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 53 2e-06
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 53 2e-06
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 53 2e-06
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 52 2e-06
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 52 2e-06
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 52 2e-06
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 52 2e-06
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 52 2e-06
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 52 2e-06
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 52 2e-06
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 52 2e-06
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 52 2e-06
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 52 2e-06
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 52 2e-06
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 52 2e-06
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 52 2e-06
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 52 2e-06
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 52 2e-06
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 52 2e-06
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 52 3e-06
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 52 4e-06
U69152-1|AAB40916.1| 567|Homo sapiens transforming growth facto... 52 4e-06
U52246-1|AAB17553.1| 567|Homo sapiens transforming growth facto... 52 4e-06
M85079-1|AAA61164.1| 567|Homo sapiens TGF-beta type II receptor... 52 4e-06
DQ377559-1|ABG65632.1| 567|Homo sapiens transforming growth fac... 52 4e-06
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 52 4e-06
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 52 4e-06
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 52 4e-06
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 52 4e-06
AY675319-1|AAT70724.1| 567|Homo sapiens transforming growth fac... 52 4e-06
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 52 4e-06
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 52 4e-06
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 52 4e-06
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 52 4e-06
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 52 4e-06
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 52 4e-06
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 52 4e-06
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 52 4e-06
Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewin... 51 5e-06
D14497-1|BAA03387.1| 467|Homo sapiens proto-oncogene protein pr... 51 5e-06
CR542284-1|CAG47079.1| 467|Homo sapiens MAP3K8 protein. 51 5e-06
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 51 5e-06
BC113566-1|AAI13567.1| 467|Homo sapiens mitogen-activated prote... 51 5e-06
BC104833-1|AAI04834.1| 467|Homo sapiens mitogen-activated prote... 51 5e-06
AY309013-1|AAP45053.1| 467|Homo sapiens mitogen-activated prote... 51 5e-06
AL161651-12|CAI14227.1| 467|Homo sapiens mitogen-activated prot... 51 5e-06
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 51 5e-06
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 51 6e-06
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 51 6e-06
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 51 6e-06
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 51 6e-06
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 51 6e-06
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 51 6e-06
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 51 6e-06
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 51 6e-06
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 51 6e-06
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 51 6e-06
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 51 6e-06
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 51 6e-06
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 51 6e-06
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 51 6e-06
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 51 6e-06
AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinas... 51 6e-06
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 51 6e-06
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 51 6e-06
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 50 8e-06
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 50 8e-06
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 50 8e-06
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 50 8e-06
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 50 8e-06
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 50 8e-06
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 50 8e-06
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 50 8e-06
AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-li... 50 8e-06
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 50 8e-06
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 50 8e-06
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 50 8e-06
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 50 8e-06
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 50 8e-06
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 50 8e-06
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 50 1e-05
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 50 1e-05
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 50 1e-05
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 50 1e-05
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 50 1e-05
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 50 1e-05
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 50 1e-05
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 50 1e-05
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 50 1e-05
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 50 1e-05
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 50 1e-05
D50683-1|BAA09332.1| 567|Homo sapiens TGF-betaIIR alpha protein. 50 1e-05
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 50 1e-05
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 50 1e-05
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 50 1e-05
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 50 1e-05
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 50 1e-05
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 50 1e-05
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 50 1e-05
EF560739-1|ABQ59049.1| 926|Homo sapiens ERN2 protein protein. 49 2e-05
EF560720-1|ABQ59030.1| 874|Homo sapiens ERN2 protein protein. 49 2e-05
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 49 2e-05
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 49 2e-05
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 49 2e-05
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 49 2e-05
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 49 2e-05
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 49 2e-05
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 49 2e-05
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 49 2e-05
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 49 2e-05
AK131280-1|BAD18455.1| 974|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 49 2e-05
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 49 2e-05
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 49 2e-05
AB047079-1|BAB21297.1| 925|Homo sapiens protein kinase/ribonucl... 49 2e-05
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 49 3e-05
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 49 3e-05
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 49 3e-05
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 49 3e-05
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 49 3e-05
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 49 3e-05
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 48 3e-05
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 48 3e-05
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 48 3e-05
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 48 3e-05
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 48 3e-05
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 48 3e-05
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 48 3e-05
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 48 3e-05
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 48 3e-05
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 48 3e-05
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 48 3e-05
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 48 3e-05
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 48 3e-05
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 48 3e-05
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 48 3e-05
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 48 3e-05
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 48 3e-05
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 48 3e-05
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 48 3e-05
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 48 3e-05
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 48 3e-05
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 48 3e-05
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 48 3e-05
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 48 3e-05
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 48 3e-05
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 48 3e-05
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 48 3e-05
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 48 3e-05
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 48 3e-05
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 48 3e-05
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 48 3e-05
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 48 3e-05
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 48 3e-05
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 48 3e-05
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 48 3e-05
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 48 3e-05
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 48 3e-05
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 48 3e-05
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 48 3e-05
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 48 3e-05
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 48 3e-05
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 48 3e-05
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 48 3e-05
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 48 3e-05
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 48 3e-05
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 48 3e-05
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 48 3e-05
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 48 5e-05
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 48 5e-05
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 48 5e-05
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 48 5e-05
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 48 5e-05
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 48 5e-05
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 48 5e-05
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 48 5e-05
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 48 5e-05
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 48 5e-05
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 48 5e-05
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 48 5e-05
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 48 5e-05
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 48 5e-05
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 48 5e-05
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 48 5e-05
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 48 5e-05
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 48 5e-05
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 48 5e-05
L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1 receptor-as... 48 6e-05
DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor ... 48 6e-05
BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein. 48 6e-05
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 48 6e-05
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 48 6e-05
BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1 receptor-... 48 6e-05
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 48 6e-05
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 48 6e-05
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 48 6e-05
AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor ... 48 6e-05
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 48 6e-05
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 48 6e-05
AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1 receptor-... 48 6e-05
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 47 8e-05
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 47 8e-05
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 47 8e-05
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 47 8e-05
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 47 8e-05
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 47 8e-05
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 47 8e-05
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 47 8e-05
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 47 8e-05
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 47 8e-05
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 47 8e-05
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 47 8e-05
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 47 8e-05
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 47 8e-05
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 47 8e-05
Z25428-1|CAA80915.1| 111|Homo sapiens protein-serine/threonine ... 47 1e-04
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 47 1e-04
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 47 1e-04
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 47 1e-04
U22512-1|AAC50713.1| 714|Homo sapiens CHUK protein. 47 1e-04
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 47 1e-04
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 47 1e-04
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 47 1e-04
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 47 1e-04
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 47 1e-04
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 47 1e-04
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 47 1e-04
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 47 1e-04
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 47 1e-04
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 47 1e-04
BC092514-1|AAH92514.1| 745|Homo sapiens conserved helix-loop-he... 47 1e-04
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 47 1e-04
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 47 1e-04
AY652653-1|AAT49098.1| 745|Homo sapiens conserved helix-loop-he... 47 1e-04
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 47 1e-04
AL138921-4|CAH72401.1| 745|Homo sapiens conserved helix-loop-he... 47 1e-04
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 47 1e-04
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 47 1e-04
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 47 1e-04
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 47 1e-04
AF080157-1|AAD08996.1| 745|Homo sapiens IkB kinase-a protein. 47 1e-04
AF012890-1|AAC51662.1| 745|Homo sapiens IKK-a kinase protein. 47 1e-04
AF009225-1|AAC51671.1| 745|Homo sapiens IkB kinase alpha subuni... 47 1e-04
AB209028-1|BAD92265.1| 726|Homo sapiens conserved helix-loop-he... 47 1e-04
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 47 1e-04
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 47 1e-04
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 47 1e-04
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 46 1e-04
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 46 1e-04
U71088-1|AAB16852.2| 444|Homo sapiens MAP kinase kinase MEK5c p... 46 1e-04
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 46 1e-04
U25265-1|AAA96146.1| 438|Homo sapiens MEK5 protein. 46 1e-04
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 46 1e-04
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 46 1e-04
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 46 1e-04
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 46 1e-04
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 46 1e-04
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 46 2e-04
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 46 2e-04
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 46 2e-04
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 46 2e-04
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 46 2e-04
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 46 2e-04
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 46 2e-04
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 46 2e-04
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 46 2e-04
M73489-1|AAA36655.1| 1073|Homo sapiens heat-stable enterotoxin r... 46 2e-04
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 46 2e-04
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 46 2e-04
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 46 2e-04
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 46 2e-04
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 46 2e-04
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 46 2e-04
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 46 2e-04
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 46 2e-04
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 46 2e-04
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 46 2e-04
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 46 2e-04
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 46 2e-04
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 46 2e-04
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 46 2e-04
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 46 2e-04
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 46 2e-04
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 46 2e-04
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 46 2e-04
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 46 2e-04
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 46 2e-04
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 46 2e-04
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 46 2e-04
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 45 3e-04
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 45 3e-04
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 45 3e-04
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 45 3e-04
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 45 3e-04
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 45 3e-04
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 45 3e-04
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 45 3e-04
BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein pr... 45 3e-04
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 45 3e-04
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 45 3e-04
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 45 3e-04
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 45 3e-04
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 45 3e-04
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 45 3e-04
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 45 3e-04
BC036021-1|AAH36021.1| 662|Homo sapiens BMP2 inducible kinase p... 45 3e-04
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 45 3e-04
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 45 3e-04
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 45 3e-04
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 45 3e-04
AL137661-1|CAB70863.1| 661|Homo sapiens hypothetical protein pr... 45 3e-04
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 45 3e-04
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 45 3e-04
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 45 3e-04
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 45 3e-04
AC098818-1|AAY40926.1| 662|Homo sapiens unknown protein. 45 3e-04
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 45 3e-04
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 45 3e-04
U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase... 45 4e-04
U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase... 45 4e-04
U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinas... 45 4e-04
U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein. 45 4e-04
L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein. 45 4e-04
DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated prote... 45 4e-04
CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein. 45 4e-04
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 45 4e-04
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 45 4e-04
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 45 4e-04
BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated prote... 45 4e-04
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 45 4e-04
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 45 4e-04
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 44 6e-04
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 44 6e-04
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 44 6e-04
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 44 6e-04
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 44 6e-04
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 44 6e-04
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 44 6e-04
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 44 6e-04
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 44 6e-04
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 44 6e-04
>BC015191-1|AAH15191.1| 322|Homo sapiens PDZ binding kinase
protein.
Length = 322
Score = 176 bits (429), Expect = 8e-44
Identities = 103/242 (42%), Positives = 143/242 (59%), Gaps = 9/242 (3%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SPF+ KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD+KS N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQI--DEDTFDMSL 854
Y GTE W E +T+ L WEMM+L PH + D+D D +
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTF 261
Query: 855 DD 860
D+
Sbjct: 262 DE 263
>AF189722-1|AAF69107.1| 322|Homo sapiens PDZ-binding kinase
protein.
Length = 322
Score = 176 bits (429), Expect = 8e-44
Identities = 103/242 (42%), Positives = 143/242 (59%), Gaps = 9/242 (3%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SPF+ KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD+KS N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQI--DEDTFDMSL 854
Y GTE W E +T+ L WEMM+L PH + D+D D +
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTF 261
Query: 855 DD 860
D+
Sbjct: 262 DE 263
>AB027250-1|BAA99577.1| 322|Homo sapiens MPAKK-like protein kinase
cap site form 2 protein.
Length = 322
Score = 176 bits (429), Expect = 8e-44
Identities = 103/242 (42%), Positives = 143/242 (59%), Gaps = 9/242 (3%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SPF+ KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD+KS N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQI--DEDTFDMSL 854
Y GTE W E +T+ L WEMM+L PH + D+D D +
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTF 261
Query: 855 DD 860
D+
Sbjct: 262 DE 263
>AB027249-1|BAA99576.1| 322|Homo sapiens MAPKK like protein kinase
protein.
Length = 322
Score = 176 bits (429), Expect = 8e-44
Identities = 103/242 (42%), Positives = 143/242 (59%), Gaps = 9/242 (3%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SPF+ KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD+KS N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQI--DEDTFDMSL 854
Y GTE W E +T+ L WEMM+L PH + D+D D +
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTF 261
Query: 855 DD 860
D+
Sbjct: 262 DE 263
>AK027291-1|BAB55019.1| 322|Homo sapiens protein ( Homo sapiens
cDNA FLJ14385 fis, clone HEMBA1002212, weakly similar to
TYROSINE-PROTEIN KINASE 2 (EC 2.7.1.112). ).
Length = 322
Score = 174 bits (423), Expect = 4e-43
Identities = 100/235 (42%), Positives = 138/235 (58%), Gaps = 7/235 (2%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SPF+ KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD++S N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIESSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQIDEDTFD 845
Y GTE W E +T+ L WEMM+L PH + D D
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDNDD 256
>AF237709-1|AAF71521.1| 322|Homo sapiens spermatogenesis-related
protein kinase protein.
Length = 322
Score = 174 bits (423), Expect = 4e-43
Identities = 102/242 (42%), Positives = 142/242 (58%), Gaps = 9/242 (3%)
Frame = +3
Query: 162 ITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPN--KVYTDRLKTE 335
I IP SP + KLG+GTGV+V + RSPR GL SPWA+K +N + VY RL E
Sbjct: 27 INIPASPIMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVKKINPICNDHYRSVYQKRLMDE 85
Query: 336 AELLQKMSHLNIVGFRAFSKGK--ILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQMLQ 506
A++L+ + H NIVG+RAF++ L L ME + SL DLIE+R PF +L+
Sbjct: 86 AKILKSLHHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILK 145
Query: 507 VAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENA 683
VA++++ L+YLH + ++LHGD+KS N+++ GDF K+CD GV+LPLDEN + D E
Sbjct: 146 VALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPE-- 203
Query: 684 GGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL-XWEMMSLMPPHSQI--DEDTFDMSL 854
Y GTE W E +T+ L WEMM+L PH + D+D D +
Sbjct: 204 --ACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTF 261
Query: 855 DD 860
D+
Sbjct: 262 DE 263
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 1/126 (0%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML 503
K E LL+KM H NIV F +F + L++ ME CD GDL+++ FS Q+L
Sbjct: 49 KKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDG--GDLMKRINRQRGVLFSEDQIL 106
Query: 504 QVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENA 683
V IS L+++H + +ILH D+K+ NI ++ + ++ KL DFG+ L+ N +
Sbjct: 107 GWFVQISLGLKHIHDR-KILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN-NSMELARTC 164
Query: 684 GGTVYY 701
GT YY
Sbjct: 165 IGTPYY 170
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 1/126 (0%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML 503
K E LL+KM H NIV F +F + L++ ME CD GDL+++ FS Q+L
Sbjct: 49 KKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDG--GDLMKRINRQRGVLFSEDQIL 106
Query: 504 QVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENA 683
V IS L+++H + +ILH D+K+ NI ++ + ++ KL DFG+ L+ N +
Sbjct: 107 GWFVQISLGLKHIHDR-KILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN-NSMELARTC 164
Query: 684 GGTVYY 701
GT YY
Sbjct: 165 IGTPYY 170
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/157 (25%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 301 KVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEF--MSKGSLLD 358
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ D Q++ +A I+ + Y+ +M +H D+++ NILV G+ ++CK+ DFG
Sbjct: 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIE-RMNYIHRDLRAANILV-GENLVCKIADFG 416
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 417 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 448
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/157 (25%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 301 KVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEF--MSKGSLLD 358
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ D Q++ +A I+ + Y+ +M +H D+++ NILV G+ ++CK+ DFG
Sbjct: 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIE-RMNYIHRDLRAANILV-GENLVCKIADFG 416
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 417 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 448
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/157 (24%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 243 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 300
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 301 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 358
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 359 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 390
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/157 (24%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 292 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 349
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 350 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 407
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 408 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 439
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/157 (24%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 295 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 352
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 410
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 411 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 442
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/157 (24%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 295 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 352
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 410
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 411 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 442
>BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to
SRC, FGR, YES protein.
Length = 482
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/157 (24%), Positives = 80/157 (50%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 240 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 297
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 298 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 355
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+ +++N ++ A + W+APE R
Sbjct: 356 LARLIEDNEYTARQGAKFPI-----KWTAPEAALYGR 387
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/151 (25%), Positives = 79/151 (52%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 292 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 349
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 350 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 407
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N ++ A + W+APE
Sbjct: 408 LARLIEDNEYTARQGAKFPI-----KWTAPE 433
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/151 (25%), Positives = 79/151 (52%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA++++K+ H +V A + +Y+ E ++ G L++
Sbjct: 295 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEY--MNKGSLLD 352
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D + ++ +A +++ + Y+ +M +H D++S NILV G+ +ICK+ DFG
Sbjct: 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIE-RMNYIHRDLRSANILV-GNGLICKIADFG 410
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N ++ A + W+APE
Sbjct: 411 LARLIEDNEYTARQGAKFPI-----KWTAPE 436
>U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein
kinase protein.
Length = 859
Score = 61.3 bits (142), Expect = 5e-09
Identities = 51/176 (28%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +3
Query: 306 KVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILY-LGMEACDLSLGDLIEKRVDDDCTP 482
K D +T+ + L+K+ H NI+ F+ Y + ME C + G L E V P
Sbjct: 152 KKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFC--AQGQLYE--VLRAGRP 207
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
+P ++ ++ I+ + YLH +I+H D+KS N+L+ D V+ K+ DFG + L +
Sbjct: 208 VTPSLLVDWSMGIAGGMNYLHLH-KIIHRDLKSPNMLITYDDVV-KISDFGTSKELSDKS 265
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSLMPPHSQID 830
K + GTV AW APEV ++ + WE+++ P+ +D
Sbjct: 266 --TKMSFAGTV-----AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVD 314
>BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein.
Length = 567
Score = 61.3 bits (142), Expect = 5e-09
Identities = 51/176 (28%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +3
Query: 306 KVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILY-LGMEACDLSLGDLIEKRVDDDCTP 482
K D +T+ + L+K+ H NI+ F+ Y + ME C + G L E V P
Sbjct: 185 KKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFC--AQGQLYE--VLRAGRP 240
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
+P ++ ++ I+ + YLH +I+H D+KS N+L+ D V+ K+ DFG + L +
Sbjct: 241 VTPSLLVDWSMGIAGGMNYLHLH-KIIHRDLKSPNMLITYDDVV-KISDFGTSKELSDKS 298
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSLMPPHSQID 830
K + GTV AW APEV ++ + WE+++ P+ +D
Sbjct: 299 --TKMSFAGTV-----AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVD 347
>AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase
protein.
Length = 859
Score = 61.3 bits (142), Expect = 5e-09
Identities = 51/176 (28%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +3
Query: 306 KVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILY-LGMEACDLSLGDLIEKRVDDDCTP 482
K D +T+ + L+K+ H NI+ F+ Y + ME C + G L E V P
Sbjct: 152 KKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFC--AQGQLYE--VLRAGRP 207
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
+P ++ ++ I+ + YLH +I+H D+KS N+L+ D V+ K+ DFG + L +
Sbjct: 208 VTPSLLVDWSMGIAGGMNYLHLH-KIIHRDLKSPNMLITYDDVV-KISDFGTSKELSDKS 265
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSLMPPHSQID 830
K + GTV AW APEV ++ + WE+++ P+ +D
Sbjct: 266 --TKMSFAGTV-----AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVD 314
>CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 60.5 bits (140), Expect = 8e-09
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 67 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMCTVDCFY 122
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 123 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 180
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 181 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 212
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 60.5 bits (140), Expect = 8e-09
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 81 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 137
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 138 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 189
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 190 MYI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 244
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 245 IYQLVAGLPP 254
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 113 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 170
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 171 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 228
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 229 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 256
>U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein.
Length = 352
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 72 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 127
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 128 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 185
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 186 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 217
>U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein.
Length = 347
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 67 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 122
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 123 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 180
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 181 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 212
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 481 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 536
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 537 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 594
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 595 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 624
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 43 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 98
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 99 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 156
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 157 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 186
>L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein.
Length = 318
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 38 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 93
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 94 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 151
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 152 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 183
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 298 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 355
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 356 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 413
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 414 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 441
>D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b
protein.
Length = 347
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 67 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 122
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 123 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 180
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 181 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 212
>CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 67 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 122
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 123 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 180
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 181 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 212
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 481 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 536
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 537 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 594
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 595 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 624
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 481 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 536
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 537 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 594
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 595 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 624
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 298 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 355
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 356 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 413
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 414 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 441
>BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 protein.
Length = 347
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G V++ VR ++G I A+K + V + + + +
Sbjct: 67 ISELGRGA-YGVVEKVRHAQSGTIM---AVKRIRATVNSQEQKRLLMDLDINMRTVDCFY 122
Query: 366 NIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYL 542
+ + A + +++ ME D SL K +D + T P +L ++AV I ALE+L
Sbjct: 123 TVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHL 180
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
H+K+ ++H D+K N+L+N + + K+CDFG++
Sbjct: 181 HSKLSVIHRDVKPSNVLINKEGHV-KMCDFGIS 212
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 298 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 355
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 356 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 413
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 414 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 441
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 1207 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 1262
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 1263 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 1320
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 1321 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 1350
>AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 298 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 355
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 356 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 413
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 414 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 441
>AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 304 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 361
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 362 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 419
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 420 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 447
>AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens
cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to
Rattus norvegicus tyrosine protein kinase pp60-c-src
mRNA. ).
Length = 251
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/153 (25%), Positives = 78/153 (50%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVD 467
K +KP + + EA++++K+ H +V A + +Y+ E +S G L++
Sbjct: 13 KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY--MSKGSLLDFLKG 70
Query: 468 DDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLP 647
+ Q++ +A I+S + Y+ +M +H D+++ NILV G+ ++CK+ DFG+
Sbjct: 71 ETGKYLRLPQLVDMAAQIASGMAYVE-RMNYVHRDLRAANILV-GENLVCKVADFGLARL 128
Query: 648 LDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
+++N ++ A + W+APE R
Sbjct: 129 IEDNEYTARQGAKFPI-----KWTAPEAALYGR 156
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+KMLN P K E +L+K H+NI+ F +S L + + C+ G
Sbjct: 366 AVKMLNVTA-PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCE---GSS 421
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F +++ +A + ++YLH K I+H D+KS NI ++ D + K+ D
Sbjct: 422 LYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAK-SIIHRDLKSNNIFLHEDLTV-KIGD 479
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G++ W APEV
Sbjct: 480 FGLATVKSRWSGSHQFEQLSGSI-----LWMAPEV 509
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 108 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 164
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 165 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 216
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 217 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 271
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 272 IYQLVAGLPP 281
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 108 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 164
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 165 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 216
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 217 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 271
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 272 IYQLVAGLPP 281
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 108 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 164
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 165 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 216
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 217 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 271
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 272 IYQLVAGLPP 281
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 108 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 164
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 165 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 216
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 217 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 271
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 272 IYQLVAGLPP 281
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 100 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 156
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 157 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 208
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 209 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 263
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 264 IYQLVAGLPP 273
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 146 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 202
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SALEYLH K I+H D+K NIL+N D
Sbjct: 203 GELLKYIRKIGSFDETCTRF-------YTAEIVSALEYLHGK-GIIHRDLKPENILLNED 254
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 255 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 309
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 310 IYQLVAGLPP 319
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K V P + E +L+K H+NI+ F + L + + C+ G
Sbjct: 373 AVKIL-KVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCE---GSS 428
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ K + T F Q++ +A + ++YLH K I+H DMKS NI ++ + K+ D
Sbjct: 429 LYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAK-NIIHRDMKSNNIFLHEGLTV-KIGD 486
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W APEV
Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSV-----LWMAPEV 516
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/175 (31%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = +3
Query: 183 FLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSH 362
+L +G G+ V LV+ R G + +K LN R ++ + EA+LL ++ H
Sbjct: 8 YLRVVGKGSYGEVT-LVKHRRDG---KQYVIKKLNLRNASSRERR-AAEQEAQLLSQLKH 62
Query: 363 LNIVGFRAFSKGK--ILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
NIV ++ +G +LY+ M C+ GDL K + Q+++ V I+ AL+
Sbjct: 63 PNIVTYKESWEGGDGLLYIVMGFCEG--GDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
YLH K ILH D+K+ N+ + +I K+ D G+ L EN GT YY
Sbjct: 121 YLHEK-HILHRDLKTQNVFLTRTNII-KVGDLGIARVL-ENHCDMASTLIGTPYY 172
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K V P + E +L+K H+NI+ F + L + + C+ G
Sbjct: 146 AVKIL-KVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCE---GSS 201
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ K + T F Q++ +A + ++YLH K I+H DMKS NI ++ + K+ D
Sbjct: 202 LYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAK-NIIHRDMKSNNIFLHEGLTV-KIGD 259
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W APEV
Sbjct: 260 FGLATVKSRWSGSQQVEQPTGSV-----LWMAPEV 289
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/175 (31%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = +3
Query: 183 FLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSH 362
+L +G G+ V LV+ R G + +K LN R ++ + EA+LL ++ H
Sbjct: 8 YLRVVGKGSYGEVT-LVKHRRDG---KQYVIKKLNLRNASSRERR-AAEQEAQLLSQLKH 62
Query: 363 LNIVGFRAFSKGK--ILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
NIV ++ +G +LY+ M C+ GDL K + Q+++ V I+ AL+
Sbjct: 63 PNIVTYKESWEGGDGLLYIVMGFCEG--GDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
YLH K ILH D+K+ N+ + +I K+ D G+ L EN GT YY
Sbjct: 121 YLHEK-HILHRDLKTQNVFLTRTNII-KVGDLGIARVL-ENHCDMASTLIGTPYY 172
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K V P + E +L+K H+NI+ F + L + + C+ G
Sbjct: 373 AVKIL-KVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCE---GSS 428
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ K + T F Q++ +A + ++YLH K I+H DMKS NI ++ + K+ D
Sbjct: 429 LYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAK-NIIHRDMKSNNIFLHEGLTV-KIGD 486
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W APEV
Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSV-----LWMAPEV 516
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/175 (31%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = +3
Query: 183 FLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSH 362
+L +G G+ V LV+ R G + +K LN R ++ + EA+LL ++ H
Sbjct: 8 YLRVVGKGSYGEVT-LVKHRRDG---KQYVIKKLNLRNASSRERR-AAEQEAQLLSQLKH 62
Query: 363 LNIVGFRAFSKGK--ILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
NIV ++ +G +LY+ M C+ GDL K + Q+++ V I+ AL+
Sbjct: 63 PNIVTYKESWEGGDGLLYIVMGFCEG--GDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
YLH K ILH D+K+ N+ + +I K+ D G+ L EN GT YY
Sbjct: 121 YLHEK-HILHRDLKTQNVFLTRTNII-KVGDLGIARVL-ENHCDMASTLIGTPYY 172
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K V P + E +L+K H+NI+ F + L + + C+ G
Sbjct: 373 AVKIL-KVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCE---GSS 428
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ K + T F Q++ +A + ++YLH K I+H DMKS NI ++ + K+ D
Sbjct: 429 LYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAK-NIIHRDMKSNNIFLHEGLTV-KIGD 486
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W APEV
Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSV-----LWMAPEV 516
>AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 isoform B variant protein.
Length = 347
Score = 58.8 bits (136), Expect = 2e-08
Identities = 32/86 (37%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL K +D + T P +L ++AV I ALE+LH+K+ ++
Sbjct: 131 FREGDV-WICMELMDTSLDKFYRKVLDKNMT--IPEDILGEIAVSIVRALEHLHSKLSVI 187
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + + K+CDFG++
Sbjct: 188 HRDVKPSNVLINKEGHV-KMCDFGIS 212
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 1/176 (0%)
Frame = +3
Query: 306 KVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILY-LGMEACDLSLGDLIEKRVDDDCTP 482
K ++ +T+ + L+K+ H NI+ F+ Y + ME C + G L E V
Sbjct: 195 KKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYC--AHGQLYE--VLRAGRK 250
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
+PR ++ + I+S + YLH +I+H D+KS N+LV + K+ DFG + L +
Sbjct: 251 ITPRLLVDWSTGIASGMNYLHLH-KIIHRDLKSPNVLVTHTDAV-KISDFGTSKELSDKS 308
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSLMPPHSQID 830
K + GTV AW APEV ++ + WE+++ P+ +D
Sbjct: 309 --TKMSFAGTV-----AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVD 357
>L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein.
Length = 393
Score = 58.0 bits (134), Expect = 4e-08
Identities = 51/155 (32%), Positives = 83/155 (53%), Gaps = 3/155 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G G V ++ P +GL+ A K+++ +KP +++ E ++L + +
Sbjct: 71 ISELGAGNGGVVFKVSHKP-SGLVM---ARKLIHLEIKP--AIRNQIIRELQVLHECNSP 124
Query: 366 NIVGFRA--FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALE 536
IVGF +S G+I + ME D D + K+ P Q+L +V++ + L
Sbjct: 125 YIVGFYGAFYSDGEIS-ICMEHMDGGSLDQVLKKAGR-----IPEQILGKVSIAVIKGLT 178
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
YL K +I+H D+K NILVN I KLCDFGV+
Sbjct: 179 YLREKHKIMHRDVKPSNILVNSRGEI-KLCDFGVS 212
>BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated protein
kinase kinase 1 protein.
Length = 393
Score = 58.0 bits (134), Expect = 4e-08
Identities = 51/155 (32%), Positives = 83/155 (53%), Gaps = 3/155 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G G V ++ P +GL+ A K+++ +KP +++ E ++L + +
Sbjct: 71 ISELGAGNGGVVFKVSHKP-SGLVM---ARKLIHLEIKP--AIRNQIIRELQVLHECNSP 124
Query: 366 NIVGFRA--FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALE 536
IVGF +S G+I + ME D D + K+ P Q+L +V++ + L
Sbjct: 125 YIVGFYGAFYSDGEIS-ICMEHMDGGSLDQVLKKAGR-----IPEQILGKVSIAVIKGLT 178
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
YL K +I+H D+K NILVN I KLCDFGV+
Sbjct: 179 YLREKHKIMHRDVKPSNILVNSRGEI-KLCDFGVS 212
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 58.0 bits (134), Expect = 4e-08
Identities = 53/173 (30%), Positives = 85/173 (49%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
L K+G G+ + LV+S G + +K +N +K + + E +L M H
Sbjct: 7 LQKIGEGSFGKAI-LVKSTEDG---RQYVIKEINISRMSSKE-REESRREVAVLANMKHP 61
Query: 366 NIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYL 542
NIV +R +F + LY+ M+ C+ GDL ++ F Q+L V I AL+++
Sbjct: 62 NIVQYRESFEENGSLYIVMDYCEG--GDLFKRINAQKGVLFQEDQILDWFVQICLALKHV 119
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
H + +ILH D+KS NI + D + +L DFG+ L+ + GT YY
Sbjct: 120 HDR-KILHRDIKSQNIFLTKDGTV-QLGDFGIARVLNST-VELARTCIGTPYY 169
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 315 TDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSP 491
T + EA LL KM H NIV F+ +F LY+ ME CD GDL++K F
Sbjct: 44 TQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCD--GGDLMQKIKQQKGKLFPE 101
Query: 492 RQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFD 671
+L + + ++H K ++LH D+KS NI + + + KL DFG L F
Sbjct: 102 DMILNWFTQMCLGVNHIH-KKRVLHRDIKSKNIFLTQNGKV-KLGDFGSARLLSNPMAFA 159
Query: 672 KENAGGTVYYGTEAW 716
G Y E W
Sbjct: 160 CTYVGTPYYVPPEIW 174
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 58.0 bits (134), Expect = 4e-08
Identities = 53/173 (30%), Positives = 85/173 (49%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
L K+G G+ + LV+S G + +K +N +K + + E +L M H
Sbjct: 7 LQKIGEGSFGKAI-LVKSTEDG---RQYVIKEINISRMSSKE-REESRREVAVLANMKHP 61
Query: 366 NIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYL 542
NIV +R +F + LY+ M+ C+ GDL ++ F Q+L V I AL+++
Sbjct: 62 NIVQYRESFEENGSLYIVMDYCEG--GDLFKRINAQKGVLFQEDQILDWFVQICLALKHV 119
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
H + +ILH D+KS NI + D + +L DFG+ L+ + GT YY
Sbjct: 120 HDR-KILHRDIKSQNIFLTKDGTV-QLGDFGIARVLNST-VELARTCIGTPYY 169
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 315 TDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSP 491
T + EA LL KM H NIV F+ +F LY+ ME CD GDL++K F
Sbjct: 44 TQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCD--GGDLMQKIKQQKGKLFPE 101
Query: 492 RQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFD 671
+L + + ++H K ++LH D+KS NI + + + KL DFG L F
Sbjct: 102 DMILNWFTQMCLGVNHIH-KKRVLHRDIKSKNIFLTQNGKV-KLGDFGSARLLSNPMAFA 159
Query: 672 KENAGGTVYYGTEAW 716
G Y E W
Sbjct: 160 CTYVGTPYYVPPEIW 174
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 315 TDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSP 491
T + EA LL KM H NIV F+ +F LY+ ME CD GDL++K F
Sbjct: 65 TQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCD--GGDLMQKIKQQKGKLFPE 122
Query: 492 RQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFD 671
+L + + ++H K ++LH D+KS NI + + + KL DFG L F
Sbjct: 123 DMILNWFTQMCLGVNHIH-KKRVLHRDIKSKNIFLTQNGKV-KLGDFGSARLLSNPMAFA 180
Query: 672 KENAGGTVYYGTEAW 716
G Y E W
Sbjct: 181 CTYVGTPYYVPPEIW 195
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 315 TDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSP 491
T + EA LL KM H NIV F+ +F LY+ ME CD GDL++K F
Sbjct: 44 TQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCD--GGDLMQKIKQQKGKLFPE 101
Query: 492 RQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFD 671
+L + + ++H K ++LH D+KS NI + + + KL DFG L F
Sbjct: 102 DMILNWFTQMCLGVNHIH-KKRVLHRDIKSKNIFLTQNGKV-KLGDFGSARLLSNPMAFA 159
Query: 672 KENAGGTVYYGTEAW 716
G Y E W
Sbjct: 160 CTYVGTPYYVPPEIW 174
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 58.0 bits (134), Expect = 4e-08
Identities = 53/173 (30%), Positives = 85/173 (49%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
L K+G G+ + LV+S G + +K +N +K + + E +L M H
Sbjct: 14 LQKIGEGSFGKAI-LVKSTEDG---RQYVIKEINISRMSSKE-REESRREVAVLANMKHP 68
Query: 366 NIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYL 542
NIV +R +F + LY+ M+ C+ GDL ++ F Q+L V I AL+++
Sbjct: 69 NIVQYRESFEENGSLYIVMDYCEG--GDLFKRINAQKGVLFQEDQILDWFVQICLALKHV 126
Query: 543 HTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
H + +ILH D+KS NI + D + +L DFG+ L+ + GT YY
Sbjct: 127 HDR-KILHRDIKSQNIFLTKDGTV-QLGDFGIARVLNST-VELARTCIGTPYY 176
>BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated protein
kinase kinase 2 protein.
Length = 400
Score = 57.6 bits (133), Expect = 6e-08
Identities = 60/184 (32%), Positives = 94/184 (51%), Gaps = 3/184 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G G V ++ P +GLI A K+++ +KP +++ E ++L + +
Sbjct: 75 ISELGAGNGGVVTKVQHRP-SGLIM---ARKLIHLEIKP--AIRNQIIRELQVLHECNSP 128
Query: 366 NIVGFRA--FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALE 536
IVGF +S G+I + ME D D + K P ++L +V++ + L
Sbjct: 129 YIVGFYGAFYSDGEIS-ICMEHMDGGSLDQVLKEAKR-----IPEEILGKVSIAVLRGLA 182
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAW 716
YL K QI+H D+K NILVN I KLCDFGV+ L I N+ + GT ++
Sbjct: 183 YLREKHQIMHRDVKPSNILVNSRGEI-KLCDFGVSGQL----IDSMANS----FVGTRSY 233
Query: 717 SAPE 728
APE
Sbjct: 234 MAPE 237
>BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated protein
kinase kinase 2 protein.
Length = 400
Score = 57.6 bits (133), Expect = 6e-08
Identities = 60/184 (32%), Positives = 94/184 (51%), Gaps = 3/184 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
+++LG G G V ++ P +GLI A K+++ +KP +++ E ++L + +
Sbjct: 75 ISELGAGNGGVVTKVQHRP-SGLIM---ARKLIHLEIKP--AIRNQIIRELQVLHECNSP 128
Query: 366 NIVGFRA--FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALE 536
IVGF +S G+I + ME D D + K P ++L +V++ + L
Sbjct: 129 YIVGFYGAFYSDGEIS-ICMEHMDGGSLDQVLKEAKR-----IPEEILGKVSIAVLRGLA 182
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAW 716
YL K QI+H D+K NILVN I KLCDFGV+ L I N+ + GT ++
Sbjct: 183 YLREKHQIMHRDVKPSNILVNSRGEI-KLCDFGVSGQL----IDSMANS----FVGTRSY 233
Query: 717 SAPE 728
APE
Sbjct: 234 MAPE 237
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 57.2 bits (132), Expect = 7e-08
Identities = 57/190 (30%), Positives = 91/190 (47%), Gaps = 7/190 (3%)
Frame = +3
Query: 267 WALKMLNKR--VKPNKV-YTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGME-ACD 431
+A+K+L KR +K NKV Y R E +++ ++ H V + F + LY G+ A +
Sbjct: 108 YAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKN 164
Query: 432 LSLGDLIEK--RVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGD 605
L I K D+ CT F +I SA EYLH K I+H D+K NIL+N D
Sbjct: 165 GELLKYIRKIGSFDETCTRF-------YTAEIVSASEYLHGK-GIIHRDLKPENILLNED 216
Query: 606 FVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSL 785
I ++ DFG L + + A + GT + +PE+ T + L +
Sbjct: 217 MHI-QITDFGTAKVLSP----ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCI 271
Query: 786 XWEMMSLMPP 815
+++++ +PP
Sbjct: 272 IYQLVAGLPP 281
>EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein.
Length = 841
Score = 56.8 bits (131), Expect = 1e-07
Identities = 54/175 (30%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = +3
Query: 183 FLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSH 362
+L +G G+ V LV+ R G + +K LN R ++ + EA+LL ++ H
Sbjct: 8 YLRVVGKGSYGEVT-LVKHRRDG---KQYVIKKLNLRNASSRERR-AAEQEAQLLSQLKH 62
Query: 363 LNIVGFRAFSKGK--ILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
+IV ++ +G +LY+ M C+ GDL K + Q+++ V I+ AL+
Sbjct: 63 PDIVTYKESWEGGDGLLYIVMGFCEG--GDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYY 701
YLH K ILH D+K+ N+ + +I K+ D G+ L EN GT YY
Sbjct: 121 YLHEK-HILHRDLKTQNVFLTRTNII-KVGDLGIARVL-ENHCDMASTLIGTPYY 172
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppressor
gene-4 protein protein.
Length = 312
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 94 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 152
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 153 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 204
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 205 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 255
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 56.8 bits (131), Expect = 1e-07
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +3
Query: 321 RLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQM 500
+++ EAE+L +SH NI+ F Y G+ SLG L + + +
Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query: 501 LQVAVDISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDK 674
+ A D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHN 159
Query: 675 ENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 160 HTTHMSL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 210
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRV 464
K + N+ + E ++L+ + NIV + AF + LYL E + ++ +L+E+
Sbjct: 45 KDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP 104
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ P ++ + A+ + H K I+H D+K N+L++ + V+ KLCDFG
Sbjct: 105 NG----VPPEKVKSYIYQLIKAIHWCH-KNDIVHRDIKPENLLISHNDVL-KLCDFGFAR 158
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA---RSVTELTSGHLVSLXWEMMSLMPP 815
L E NA T Y T + +PE+ A +SV + G ++ + L P
Sbjct: 159 NLSEG-----NNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPG 213
Query: 816 HSQIDE 833
S+ID+
Sbjct: 214 ESEIDQ 219
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRV 464
K + N+ + E ++L+ + NIV + AF + LYL E + ++ +L+E+
Sbjct: 45 KDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP 104
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ P ++ + A+ + H K I+H D+K N+L++ + V+ KLCDFG
Sbjct: 105 NG----VPPEKVKSYIYQLIKAIHWCH-KNDIVHRDIKPENLLISHNDVL-KLCDFGFAR 158
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA---RSVTELTSGHLVSLXWEMMSLMPP 815
L E NA T Y T + +PE+ A +SV + G ++ + L P
Sbjct: 159 NLSEG-----NNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPG 213
Query: 816 HSQIDE 833
S+ID+
Sbjct: 214 ESEIDQ 219
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRV 464
K + N+ + E ++L+ + NIV + AF + LYL E + ++ +L+E+
Sbjct: 45 KDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP 104
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ P ++ + A+ + H K I+H D+K N+L++ + V+ KLCDFG
Sbjct: 105 NG----VPPEKVKSYIYQLIKAIHWCH-KNDIVHRDIKPENLLISHNDVL-KLCDFGFAR 158
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA---RSVTELTSGHLVSLXWEMMSLMPP 815
L E NA T Y T + +PE+ A +SV + G ++ + L P
Sbjct: 159 NLSEG-----NNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPG 213
Query: 816 HSQIDE 833
S+ID+
Sbjct: 214 ESEIDQ 219
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRV 464
K + N+ + E ++L+ + NIV + AF + LYL E + ++ +L+E+
Sbjct: 45 KDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP 104
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ P ++ + A+ + H K I+H D+K N+L++ + V+ KLCDFG
Sbjct: 105 NG----VPPEKVKSYIYQLIKAIHWCH-KNDIVHRDIKPENLLISHNDVL-KLCDFGFAR 158
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA---RSVTELTSGHLVSLXWEMMSLMPP 815
L E NA T Y T + +PE+ A +SV + G ++ + L P
Sbjct: 159 NLSEG-----NNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPG 213
Query: 816 HSQIDE 833
S+ID+
Sbjct: 214 ESEIDQ 219
>X96757-1|CAA65532.1| 334|Homo sapiens MAP kinase kinase protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>U49732-1|AAB05035.1| 334|Homo sapiens MAP kinase kinase MEK6
protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>U39657-1|AAC50389.1| 334|Homo sapiens MAP kinase kinase 6 protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>U39656-1|AAC50388.1| 334|Homo sapiens MAP kinase kinase 6 protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 249 GLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRA-FSKGKILY 410
G++++ K + +K K YT++ + EA ++ + SH NI+ SK K +
Sbjct: 630 GMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMM 689
Query: 411 LGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNI 590
+ E + D + D + FS Q++ + I++ ++YL M +H D+ + NI
Sbjct: 690 IITEYMENGALDKFLREKDGE---FSVLQLVGMLRGIAAGMKYL-ANMNYVHRDLAARNI 745
Query: 591 LVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSG 770
LVN + V CK+ DFG++ L+++ +GG + W+APE + + +
Sbjct: 746 LVNSNLV-CKVSDFGLSRVLEDDPEATYTTSGGKI---PIRWTAPEAISYRKFTSASDVW 801
Query: 771 HLVSLXWEMMS 803
+ WE+M+
Sbjct: 802 SFGIVMWEVMT 812
>D87905-1|BAA13496.1| 334|Homo sapiens mitogen-activated protein 6
protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 249 GLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRA-FSKGKILY 410
G++++ K + +K K YT++ + EA ++ + SH NI+ SK K +
Sbjct: 630 GMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMM 689
Query: 411 LGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNI 590
+ E + D + D + FS Q++ + I++ ++YL M +H D+ + NI
Sbjct: 690 IITEYMENGALDKFLREKDGE---FSVLQLVGMLRGIAAGMKYL-ANMNYVHRDLAARNI 745
Query: 591 LVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSG 770
LVN + V CK+ DFG++ L+++ +GG + W+APE + + +
Sbjct: 746 LVNSNLV-CKVSDFGLSRVLEDDPEATYTTSGGKI---PIRWTAPEAISYRKFTSASDVW 801
Query: 771 HLVSLXWEMMS 803
+ WE+M+
Sbjct: 802 SFGIVMWEVMT 812
>BC012009-1|AAH12009.1| 334|Homo sapiens mitogen-activated protein
kinase kinase 6 protein.
Length = 334
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +3
Query: 387 FSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQIL 563
F +G + ++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++
Sbjct: 120 FREGDV-WICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVI 176
Query: 564 HGDMKSYNILVNGDFVICKLCDFGVT 641
H D+K N+L+N + K+CDFG++
Sbjct: 177 HRDVKPSNVLINALGQV-KMCDFGIS 201
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 249 GLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRA-FSKGKILY 410
G++++ K + +K K YT++ + EA ++ + SH NI+ SK K +
Sbjct: 630 GMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMM 689
Query: 411 LGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNI 590
+ E + D + D + FS Q++ + I++ ++YL M +H D+ + NI
Sbjct: 690 IITEYMENGALDKFLREKDGE---FSVLQLVGMLRGIAAGMKYL-ANMNYVHRDLAARNI 745
Query: 591 LVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSG 770
LVN + V CK+ DFG++ L+++ +GG + W+APE + + +
Sbjct: 746 LVNSNLV-CKVSDFGLSRVLEDDPEATYTTSGGKI---PIRWTAPEAISYRKFTSASDVW 801
Query: 771 HLVSLXWEMMS 803
+ WE+M+
Sbjct: 802 SFGIVMWEVMT 812
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>U39065-1|AAB03705.1| 334|Homo sapiens MAP kinase kinase 6b
protein.
Length = 334
Score = 55.2 bits (127), Expect = 3e-07
Identities = 29/80 (36%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Frame = +3
Query: 405 LYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQILHGDMKS 581
+++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++H D+K
Sbjct: 125 MWICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVIHRDVKP 182
Query: 582 YNILVNGDFVICKLCDFGVT 641
N+L+N + K+CDFG++
Sbjct: 183 SNVLINALGQV-KMCDFGIS 201
>U39064-1|AAB03708.1| 278|Homo sapiens MAP kinase kinase 6 protein.
Length = 278
Score = 55.2 bits (127), Expect = 3e-07
Identities = 29/80 (36%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Frame = +3
Query: 405 LYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQILHGDMKS 581
+++ ME D SL ++ +D T P +L ++AV I ALE+LH+K+ ++H D+K
Sbjct: 69 MWICMELMDTSLDKFYKQVIDKGQT--IPEDILGKIAVSIVKALEHLHSKLSVIHRDVKP 126
Query: 582 YNILVNGDFVICKLCDFGVT 641
N+L+N + K+CDFG++
Sbjct: 127 SNVLINALGQV-KMCDFGIS 145
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/184 (27%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E +++++ + NIV F ++ G L++ ME L+ G
Sbjct: 276 AIKQINLQKQPKK---ELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEY--LAGGS 330
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + + C Q+ V + ALE+LH Q++H D+KS N+L+ + + KL
Sbjct: 331 LTDVVTETAC--MDEAQIAAVCRECLQALEFLHAN-QVIHRDIKSDNVLLGMEGSV-KLT 386
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 387 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 440
Query: 807 MPPH 818
PP+
Sbjct: 441 EPPY 444
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 55.2 bits (127), Expect = 3e-07
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 34 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 85
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 86 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 143
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 144 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 198
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT W APEV V ++ S + ++ EM PP++
Sbjct: 199 TDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 250
Query: 825 I 827
I
Sbjct: 251 I 251
>Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine
protein-kinase protein.
Length = 947
Score = 54.8 bits (126), Expect = 4e-07
Identities = 37/99 (37%), Positives = 55/99 (55%)
Frame = +3
Query: 435 SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVI 614
SLG L++++ C P R + + + LEYLH++ +ILHGD+K+ N+L++ D
Sbjct: 476 SLGQLVKEQ---GCLP-EDRALYYLGQALEG-LEYLHSR-RILHGDVKADNVLLSSDGSH 529
Query: 615 CKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
LCDFG + L +G+ K G GTE APEV
Sbjct: 530 AALCDFGHAVCLQPDGL-GKSLLTGDYIPGTETHMAPEV 567
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/162 (24%), Positives = 77/162 (47%)
Frame = +3
Query: 243 RAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGME 422
R G + K+ K +K + RL EA L++++ H +V A + +Y+ E
Sbjct: 259 RCGWGTTTGTTKVAVKSLKQGSMSAGRLPAEANLMKQLQHQRLVRLYAVVTQEPIYIITE 318
Query: 423 ACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNG 602
+ G L++ + ++L +A I+ + ++ + I H D+++ NILV+
Sbjct: 319 Y--MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS- 374
Query: 603 DFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
D + CK+ DFG+ +++N +E A + W+APE
Sbjct: 375 DTLSCKIADFGLARLIEDNEYTAREGAKFPI-----KWTAPE 411
>DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 54.8 bits (126), Expect = 4e-07
Identities = 37/99 (37%), Positives = 55/99 (55%)
Frame = +3
Query: 435 SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVI 614
SLG L++++ C P R + + + LEYLH++ +ILHGD+K+ N+L++ D
Sbjct: 476 SLGQLVKEQ---GCLP-EDRALYYLGQALEG-LEYLHSR-RILHGDVKADNVLLSSDGSH 529
Query: 615 CKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
LCDFG + L +G+ K G GTE APEV
Sbjct: 530 AALCDFGHAVCLQPDGL-GKSLLTGDYIPGTETHMAPEV 567
>BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 54.8 bits (126), Expect = 4e-07
Identities = 37/99 (37%), Positives = 55/99 (55%)
Frame = +3
Query: 435 SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVI 614
SLG L++++ C P R + + + LEYLH++ +ILHGD+K+ N+L++ D
Sbjct: 476 SLGQLVKEQ---GCLP-EDRALYYLGQALEG-LEYLHSR-RILHGDVKADNVLLSSDGSH 529
Query: 615 CKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
LCDFG + L +G+ K G GTE APEV
Sbjct: 530 AALCDFGHAVCLQPDGL-GKSLLTGDYIPGTETHMAPEV 567
>Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein.
Length = 459
Score = 54.4 bits (125), Expect = 5e-07
Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQML 503
+ EA L KM H NIV F+ +F LY+ ME CD GDL++K F +L
Sbjct: 1 RKEAVLSAKMKHPNIVAFKESFEAEGHLYIVMEYCD--GGDLMQKIKQQKGKLFPEDMIL 58
Query: 504 QVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENA 683
+ + ++H K ++LH D+KS NI + + + KL DFG L F
Sbjct: 59 NWFTQMCLGVNHIH-KKRVLHRDIKSKNIFLTQNGKV-KLGDFGSARLLSNPMAFACTYV 116
Query: 684 GGTVYYGTEAW 716
G Y E W
Sbjct: 117 GTPYYVPPEIW 127
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 54.4 bits (125), Expect = 5e-07
Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGME-ACDLSLG 443
A+K +N + +P K + + E +++++ + NIV F ++ G L++ ME SL
Sbjct: 245 AIKQINLQKQPKK---ELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGRSLT 301
Query: 444 DLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKL 623
D++ + D+ Q+ V + ALE+LH Q++H D+KS N+L+ + + KL
Sbjct: 302 DVVTETCMDEA------QIAAVCRECLQALEFLHAN-QVIHRDIKSDNVLLGMEGSV-KL 353
Query: 624 CDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 354 TDFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVE 407
Query: 804 LMPPH 818
PP+
Sbjct: 408 GEPPY 412
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 428 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 484
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 485 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 541
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 542 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 591
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 101 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 157
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 158 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 214
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 215 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 264
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 5e-07
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = +3
Query: 288 KRVKPNKVYTDRLKTEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKRV 464
K +K + D EA+++ +SH +V + +K + +++ E ++ G L+ +
Sbjct: 430 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEY--MANGCLLNY-L 486
Query: 465 DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTL 644
+ F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 487 REMRHRFQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS- 543
Query: 645 PLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 544 ----RYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 593
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 54.0 bits (124), Expect = 7e-07
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 5/207 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEV 731
+ K N TV GT W APEV
Sbjct: 175 TDT--MAKRN---TV-IGTPFWMAPEV 195
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 54.0 bits (124), Expect = 7e-07
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E +++++ + NIV F ++ G L++ ME L+ G
Sbjct: 276 AIKQINLQKQPKK---ELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEY--LAGGS 330
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + ALE+LH Q++H D+KS N+L+ + + KL
Sbjct: 331 LTDV-VTETC--MDEAQIAAVCRECLQALEFLHAN-QVIHRDIKSDNVLLGMEGSV-KLT 385
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 386 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
Query: 807 MPPH 818
PP+
Sbjct: 440 EPPY 443
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 53.2 bits (122), Expect = 1e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + + C+ G
Sbjct: 43 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILPFMGFMTRPGVAIITQWCE---GSS 98
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 99 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 156
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G V W A EV
Sbjct: 157 FGLATVKTRWSGAQPLEQPSGPV-----LWMAAEV 186
>BC067760-1|AAH67760.1| 380|Homo sapiens LOC407835 protein protein.
Length = 380
Score = 53.2 bits (122), Expect = 1e-06
Identities = 69/232 (29%), Positives = 108/232 (46%), Gaps = 8/232 (3%)
Frame = +3
Query: 189 NKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLN 368
++L G G V ++ P +GLI A K+++ +KP +++ E ++L + +
Sbjct: 75 SELDAGNGGVVTKVQHRP-SGLIM---ARKLIHLEIKP--AIRNQIIREHQVLHECNSPY 128
Query: 369 IVGFR-AFSKGKILYLGMEACD---LSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
IVGF AF + + + ME D L G KR+ +D + +V++ + L
Sbjct: 129 IVGFYGAFYCDREISICMEHMDGGSLDQGLKEAKRIPEDI-------LGKVSIAVLRGLA 181
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAW 716
YL K QI+H ++K NILVN I KLCDFGV+ L I N+ + GT ++
Sbjct: 182 YLREKHQIMHRNVKPSNILVNSRGEI-KLCDFGVSGQL----IDSMANS----FMGTRSY 232
Query: 717 SAPE----VXTXARSVTELTSGHLVSLXWEMMSLMPPHSQIDEDTFDMSLDD 860
APE +SV LV L E + PP ++ E F + D
Sbjct: 233 MAPERLQGTHYSVQSVIWSMDLSLVELAIERYPIPPPDAKELEAIFGQPVVD 284
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 1/148 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
ALK + K + K + L+ E E+++ + H NIV +F K + + D + G+
Sbjct: 31 ALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVV---VTDYAEGE 86
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + DD P Q+ +A + SAL YLH+ +ILH DMK NIL+ I KLC
Sbjct: 87 LFQILEDDGKLPED--QVQAIAAQLVSALYYLHSH-RILHRDMKPQNILLAKGGGI-KLC 142
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTE 710
DFG + N + G +Y E
Sbjct: 143 DFGFARAMSTNTMVLTSIKGTPLYMSPE 170
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 1/148 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
ALK + K + K + L+ E E+++ + H NIV +F K + + D + G+
Sbjct: 31 ALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVV---VTDYAEGE 86
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + DD P Q+ +A + SAL YLH+ +ILH DMK NIL+ I KLC
Sbjct: 87 LFQILEDDGKLPED--QVQAIAAQLVSALYYLHSH-RILHRDMKPQNILLAKGGGI-KLC 142
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTE 710
DFG + N + G +Y E
Sbjct: 143 DFGFARAMSTNTMVLTSIKGTPLYMSPE 170
>AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein.
Length = 400
Score = 53.2 bits (122), Expect = 1e-06
Identities = 45/168 (26%), Positives = 78/168 (46%), Gaps = 3/168 (1%)
Frame = +3
Query: 336 AELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
AE+L +SH NI+ F Y G+ SLG L + + ++ A
Sbjct: 1 AEILSVLSHRNIIQFYGVILEPPNY-GIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 59
Query: 516 DISSALEYLHTK--MQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
D++ + YLH + ++++H D+KS N+++ D V+ K+CDFG + F
Sbjct: 60 DVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVL-KICDFGASR-------FHNHTTHM 111
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVS-LXWEMMSLMPPHSQID 830
++ GT W APEV + V+E + + WEM++ P ++
Sbjct: 112 SL-VGTFPWMAPEV-IQSLPVSETCDTYSYGVVLWEMLTREVPFKGLE 157
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 1/148 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
ALK + K + K + L+ E E+++ + H NIV +F K + + D + G+
Sbjct: 48 ALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVV---VTDYAEGE 103
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + DD P Q+ +A + SAL YLH+ +ILH DMK NIL+ I KLC
Sbjct: 104 LFQILEDDGKLPED--QVQAIAAQLVSALYYLHSH-RILHRDMKPQNILLAKGGGI-KLC 159
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTE 710
DFG + N + G +Y E
Sbjct: 160 DFGFARAMSTNTMVLTSIKGTPLYMSPE 187
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein.
Length = 348
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 108 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 165
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 166 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 223
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 224 LARVIEDNEYTAREGAKFPI-----KWTAPE 249
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 52.8 bits (121), Expect = 2e-06
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 297 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 351
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + ALE+LH+ Q++H D+KS NIL+ D + KL
Sbjct: 352 LTDV-VTETC--MDEGQIAAVCRECLQALEFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 406
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 407 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEG 460
Query: 807 MPPH 818
PP+
Sbjct: 461 EPPY 464
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 52.8 bits (121), Expect = 2e-06
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
++T+ +L LG GT V+ LV+ G +A+K+L K V K TE
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVI-LVKEKATGRY---YAMKILKKEVIVAKDEVAHTLTEN 199
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + +F L ME + G+L + FS +
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANG--GELFFHLSRERV--FSEDRARFYGA 255
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SAL+YLH++ +++ D+K N++++ D I K+ DFG L + GI K+ A
Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHI-KITDFG----LCKEGI--KDGATMKT 308
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 309 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL 362
>M16592-1|AAA52644.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 265 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 322
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 323 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 380
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 381 LARVIEDNEYTAREGAKFPI-----KWTAPE 406
>M16591-1|AAA52643.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 265 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 322
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 323 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 380
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 381 LARVIEDNEYTAREGAKFPI-----KWTAPE 406
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 286 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 343
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 401
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 402 LARVIEDNEYTAREGAKFPI-----KWTAPE 427
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 52.8 bits (121), Expect = 2e-06
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 297 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 351
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + ALE+LH+ Q++H D+KS NIL+ D + KL
Sbjct: 352 LTDV-VTETC--MDEGQIAAVCRECLQALEFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 406
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 407 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEG 460
Query: 807 MPPH 818
PP+
Sbjct: 461 EPPY 464
>BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 286 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 343
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 401
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 402 LARVIEDNEYTAREGAKFPI-----KWTAPE 427
>BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 286 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 343
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 401
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 402 LARVIEDNEYTAREGAKFPI-----KWTAPE 427
>BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 286 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 343
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 401
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 402 LARVIEDNEYTAREGAKFPI-----KWTAPE 427
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 52.8 bits (121), Expect = 2e-06
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
++T+ +L LG GT V+ LV+ G +A+K+L K V K TE
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVI-LVKEKATGRY---YAMKILKKEVIVAKDEVAHTLTEN 199
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + +F L ME + G+L + FS +
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANG--GELFFHLSRERV--FSEDRARFYGA 255
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SAL+YLH++ +++ D+K N++++ D I K+ DFG L + GI K+ A
Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHI-KITDFG----LCKEGI--KDGATMKT 308
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 309 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL 362
>BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 286 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 343
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 401
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 402 LARVIEDNEYTAREGAKFPI-----KWTAPE 427
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 337 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 392
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 393 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 450
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 451 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 480
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 52.8 bits (121), Expect = 2e-06
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDL 449
A+K+L K +P K E ++L+K H+NI+ F F + + C+ G
Sbjct: 334 AVKVL-KVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCE---GSS 389
Query: 450 IEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCD 629
+ + T F Q++ VA + ++YLH K I+H D+KS NI ++ + K+ D
Sbjct: 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAK-NIIHRDLKSNNIFLHEGLTV-KIGD 447
Query: 630 FGV-TLPLDENGIFDKENAGGTVYYGTEAWSAPEV 731
FG+ T+ +G E G+V W A EV
Sbjct: 448 FGLATVKTRWSGAQPLEQPSGSV-----LWMAAEV 477
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 52.8 bits (121), Expect = 2e-06
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
++T+ +L LG GT V+ LV+ G +A+K+L K V K TE
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVI-LVKEKATGRY---YAMKILKKEVIVAKDEVAHTLTEN 199
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + +F L ME + G+L + FS +
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANG--GELFFHLSRERV--FSEDRARFYGA 255
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SAL+YLH++ +++ D+K N++++ D I K+ DFG L + GI K+ A
Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHI-KITDFG----LCKEGI--KDGATMKT 308
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 309 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL 362
>AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 265 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 322
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 323 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 380
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 381 LARVIEDNEYTAREGAKFPI-----KWTAPE 406
>AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 264 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 321
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 322 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 379
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 380 LARVIEDNEYTAREGAKFPI-----KWTAPE 405
>AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 265 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 322
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 323 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 380
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 381 LARVIEDNEYTAREGAKFPI-----KWTAPE 406
>AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 264 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 321
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 322 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 379
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 380 LARVIEDNEYTAREGAKFPI-----KWTAPE 405
>AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22779 fis, clone KAIA1741. ).
Length = 505
Score = 52.8 bits (121), Expect = 2e-06
Identities = 35/151 (23%), Positives = 74/151 (49%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 265 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 322
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + I H D+++ NILV+ V CK+ DFG
Sbjct: 323 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYI-HRDLRAANILVSASLV-CKIADFG 380
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 381 LARVIEDNEYTAREGAKFPI-----KWTAPE 406
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 52.8 bits (121), Expect = 2e-06
Identities = 65/234 (27%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
++T+ +L LG GT V+ LV+ G +A+K+L K V K TE
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVI-LVKEKATGRY---YAMKILKKEVIVAKDEVAHTLTEN 199
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + +F L ME + G+L + FS +
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANG--GELFFHLSRERV--FSEDRARFYGA 255
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SAL+YLH++ +++ D+K N++++ D I K+ DFG L + GI K+ A
Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHI-KITDFG----LCKEGI--KDGATMKT 308
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 309 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL 362
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 52.8 bits (121), Expect = 2e-06
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 297 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 351
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + ALE+LH+ Q++H D+KS NIL+ D + KL
Sbjct: 352 LTDV-VTETC--MDEGQIAAVCRECLQALEFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 406
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 407 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEG 460
Query: 807 MPPH 818
PP+
Sbjct: 461 EPPY 464
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 269 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 326
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 327 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 384
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 385 LARLIEDNEYTAREGAKFPI-----KWTAPE 410
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 269 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 326
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 327 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 384
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 385 LARLIEDNEYTAREGAKFPI-----KWTAPE 410
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/209 (24%), Positives = 91/209 (43%), Gaps = 6/209 (2%)
Frame = +3
Query: 120 QTPQKSIKPFDNDKITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWA------LKM 281
Q PQK KP+ D+ +P L+LV AG W K+
Sbjct: 227 QKPQKPQKPWWEDEWEVPRE-------------TLKLVERLGAGQFGEVWMGYYNGHTKV 273
Query: 282 LNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKR 461
K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 274 AVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVDFL 331
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG+
Sbjct: 332 KTPSGIKLTINKLLDMAAQIAEGMVFIEERNYI-HRDLRAANILVS-DTLSCKIADFGLA 389
Query: 642 LPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+++N +E A + W+APE
Sbjct: 390 RLIEDNEYTAREGAKFPI-----KWTAPE 413
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 52.4 bits (120), Expect = 2e-06
Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
K+T+ +L LG GT V+ LVR G +A+K+L K V K TE+
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVI-LVREKATGRY---YAMKILRKEVIIAKDEVAHTVTES 201
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + AF L ME + G+L + F+ +
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANG--GELFFHLSRERV--FTEERARFYGA 257
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SALEYLH++ +++ D+K N++++ D I K+ DFG L + GI D A
Sbjct: 258 EIVSALEYLHSR-DVVYRDIKLENLMLDKDGHI-KITDFG----LCKEGISD--GATMKT 309
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 310 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELIL 363
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
K+T+ +L LG GT V+ LVR G +A+K+L K V K TE+
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVI-LVREKATGRY---YAMKILRKEVIIAKDEVAHTVTES 201
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + AF L ME + G+L + F+ +
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANG--GELFFHLSRERV--FTEERARFYGA 257
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SALEYLH++ +++ D+K N++++ D I K+ DFG L + GI D A
Sbjct: 258 EIVSALEYLHSR-DVVYRDIKLENLMLDKDGHI-KITDFG----LCKEGISD--GATMKT 309
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 310 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELIL 363
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 269 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 326
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 327 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 384
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 385 LARLIEDNEYTAREGAKFPI-----KWTAPE 410
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 261 SPWALKMLNKRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACD 431
+P K+ KR+ K T D L E + + + H NIV + +F L+L M+
Sbjct: 37 APKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLS 96
Query: 432 L-SLGDLIEKRV---DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVN 599
S+ D+I+ V + + + ++ LEYLH QI H D+K+ NIL+
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQI-HRDVKAGNILLG 155
Query: 600 GDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
D + ++ DFGV+ L G + T + GT W APEV R
Sbjct: 156 EDGSV-QIADFGVSAFLATGGDITRNKVRKT-FVGTPCWMAPEVMEQVR 202
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 52.4 bits (120), Expect = 2e-06
Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
K+T+ +L LG GT V+ LVR G +A+K+L K V K TE+
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVI-LVREKATGRY---YAMKILRKEVIIAKDEVAHTVTES 201
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + AF L ME + G+L + F+ +
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANG--GELFFHLSRERV--FTEERARFYGA 257
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SALEYLH++ +++ D+K N++++ D I K+ DFG L + GI D A
Sbjct: 258 EIVSALEYLHSR-DVVYRDIKLENLMLDKDGHI-KITDFG----LCKEGISD--GATMKT 309
Query: 696 YYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMM-SLMPPHSQIDEDTFDMSL 854
+ GT + APEV + L + +EMM +P ++Q E F++ L
Sbjct: 310 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELIL 363
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +3
Query: 192 KLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNI 371
K+G G+ ++ L R +G A+KM++ R + + + L E +++ H N+
Sbjct: 412 KIGEGS-TGIVCLAREKHSG---RQVAVKMMDLRKQQRR---ELLFNEVVIMRDYQHFNV 464
Query: 372 VG-FRAFSKGKILYLGMEACDL-SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLH 545
V ++++ G+ L++ ME +L D++ + + Q+ V + AL YLH
Sbjct: 465 VEMYKSYLVGEELWVLMEFLQGGALTDIVSQ------VRLNEEQIATVCEAVLQALAYLH 518
Query: 546 TKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAP 725
+ ++H D+KS +IL+ D + KL DFG + ++ + +++ GT Y W AP
Sbjct: 519 AQ-GVIHRDIKSDSILLTLDGRV-KLSDFGFCAQISKD-VPKRKSLVGTPY-----WMAP 570
Query: 726 EVXTXARSVTELTSGHLVSLXWEMMSLMPPH 818
EV + + TE+ L + EM+ PP+
Sbjct: 571 EVISRSLYATEVDIWSLGIMVIEMVDGEPPY 601
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 261 SPWALKMLNKRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACD 431
+P K+ KR+ K T D L E + + + H NIV + +F L+L M+
Sbjct: 37 APKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLS 96
Query: 432 L-SLGDLIEKRV---DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVN 599
S+ D+I+ V + + + ++ LEYLH QI H D+K+ NIL+
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQI-HRDVKAGNILLG 155
Query: 600 GDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
D + ++ DFGV+ L G + T + GT W APEV R
Sbjct: 156 EDGSV-QIADFGVSAFLATGGDITRNKVRKT-FVGTPCWMAPEVMEQVR 202
>AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 256 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 313
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 314 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 371
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 372 LARLIEDNEYTAREGAKFPI-----KWTAPE 397
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 276 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 333
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 334 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 391
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 392 LARLIEDNEYTAREGAKFPI-----KWTAPE 417
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +3
Query: 192 KLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNI 371
K+G G+ ++ L R +G A+KM++ R + + + L E +++ H N+
Sbjct: 412 KIGEGS-TGIVCLAREKHSG---RQVAVKMMDLRKQQRR---ELLFNEVVIMRDYQHFNV 464
Query: 372 VG-FRAFSKGKILYLGMEACDL-SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLH 545
V ++++ G+ L++ ME +L D++ + + Q+ V + AL YLH
Sbjct: 465 VEMYKSYLVGEELWVLMEFLQGGALTDIVSQ------VRLNEEQIATVCEAVLQALAYLH 518
Query: 546 TKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAP 725
+ ++H D+KS +IL+ D + KL DFG + ++ + +++ GT Y W AP
Sbjct: 519 AQ-GVIHRDIKSDSILLTLDGRV-KLSDFGFCAQISKD-VPKRKSLVGTPY-----WMAP 570
Query: 726 EVXTXARSVTELTSGHLVSLXWEMMSLMPPH 818
EV + + TE+ L + EM+ PP+
Sbjct: 571 EVISRSLYATEVDIWSLGIMVIEMVDGEPPY 601
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
Frame = +3
Query: 192 KLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNI 371
K+G G+ ++ L R +G A+KM++ R + + + L E +++ H N+
Sbjct: 412 KIGEGS-TGIVCLAREKHSG---RQVAVKMMDLRKQQRR---ELLFNEVVIMRDYQHFNV 464
Query: 372 VG-FRAFSKGKILYLGMEACDL-SLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLH 545
V ++++ G+ L++ ME +L D++ + + Q+ V + AL YLH
Sbjct: 465 VEMYKSYLVGEELWVLMEFLQGGALTDIVSQ------VRLNEEQIATVCEAVLQALAYLH 518
Query: 546 TKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAP 725
+ ++H D+KS +IL+ D + KL DFG + ++ + +++ GT Y W AP
Sbjct: 519 AQ-GVIHRDIKSDSILLTLDGRV-KLSDFGFCAQISKD-VPKRKSLVGTPY-----WMAP 570
Query: 726 EVXTXARSVTELTSGHLVSLXWEMMSLMPPH 818
EV + + TE+ L + EM+ PP+
Sbjct: 571 EVISRSLYATEVDIWSLGIMVIEMVDGEPPY 601
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/151 (24%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +K + D EA L++++ H +V A + +Y+ E + G L++
Sbjct: 256 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY--MENGSLVD 313
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
+ ++L +A I+ + ++ + I H D+++ NILV+ D + CK+ DFG
Sbjct: 314 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI-HRDLRAANILVS-DTLSCKIADFG 371
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 372 LARLIEDNEYTAREGAKFPI-----KWTAPE 397
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 261 SPWALKMLNKRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACD 431
+P K+ KR+ K T D L E + + + H NIV + +F L+L M+
Sbjct: 37 APKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLS 96
Query: 432 L-SLGDLIEKRV---DDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVN 599
S+ D+I+ V + + + ++ LEYLH QI H D+K+ NIL+
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQI-HRDVKAGNILLG 155
Query: 600 GDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
D + ++ DFGV+ L G + T + GT W APEV R
Sbjct: 156 EDGSV-QIADFGVSAFLATGGDITRNKVRKT-FVGTPCWMAPEVMEQVR 202
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 52.0 bits (119), Expect = 3e-06
Identities = 54/200 (27%), Positives = 93/200 (46%), Gaps = 3/200 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGD 446
A+K L K P + + L+ EA ++ + SH +I+ +K K + + E + + D
Sbjct: 662 AIKTL-KDTSPGGQWWNFLR-EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENAALD 719
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
+ +D P MLQ I+S + YL + +H D+ + NILVN + + CK+
Sbjct: 720 AFLREREDQLVPGQLVAMLQ---GIASGMNYL-SNHNYVHRDLAARNILVNQN-LCCKVS 774
Query: 627 DFGVTLPLDE-NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG+T LD+ +G + E GG + W+APE T + WE++S
Sbjct: 775 DFGLTRLLDDFDGTY--ETQGGKI---PIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLS 829
Query: 804 L-MPPHSQIDEDTFDMSLDD 860
P+ ++ S++D
Sbjct: 830 FGDKPYGEMSNQEVMKSIED 849
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 3/200 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGD 446
A+K L K P + + L+ EA ++ + SH +I+ +K K + + E + D
Sbjct: 369 AIKTL-KDTSPGGQWWNFLR-EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 426
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
+ +D P MLQ I+S + YL + +H D+ + NILVN + + CK+
Sbjct: 427 AFLREREDQLVPGQLVAMLQ---GIASGMNYL-SNHNYVHRDLAARNILVNQN-LCCKVS 481
Query: 627 DFGVTLPLDE-NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG+T LD+ +G + E GG + W+APE T + WE++S
Sbjct: 482 DFGLTRLLDDFDGTY--ETQGGKI---PIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLS 536
Query: 804 L-MPPHSQIDEDTFDMSLDD 860
P+ ++ S++D
Sbjct: 537 FGDKPYGEMSNQEVMKSIED 556
>U69152-1|AAB40916.1| 567|Homo sapiens transforming growth
factor-beta type II receptor protein.
Length = 567
Score = 51.6 bits (118), Expect = 4e-06
Identities = 30/62 (48%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+KS NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLKSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>U52246-1|AAB17553.1| 567|Homo sapiens transforming growth
factor-beta type II receptor protein.
Length = 567
Score = 51.6 bits (118), Expect = 4e-06
Identities = 30/62 (48%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+KS NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLKSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>M85079-1|AAA61164.1| 567|Homo sapiens TGF-beta type II receptor
protein.
Length = 567
Score = 51.6 bits (118), Expect = 4e-06
Identities = 30/62 (48%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+KS NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLKSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>DQ377559-1|ABG65632.1| 567|Homo sapiens transforming growth factor
beta receptor II protein.
Length = 567
Score = 51.6 bits (118), Expect = 4e-06
Identities = 30/62 (48%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+KS NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLKSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 3/200 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGD 446
A+K L K P + + L+ EA ++ + SH +I+ +K K + + E + D
Sbjct: 654 AIKTL-KDTSPGGQWWNFLR-EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
+ +D P MLQ I+S + YL + +H D+ + NILVN + + CK+
Sbjct: 712 AFLREREDQLVPGQLVAMLQ---GIASGMNYL-SNHNYVHRDLAARNILVNQN-LCCKVS 766
Query: 627 DFGVTLPLDE-NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG+T LD+ +G + E GG + W+APE T + WE++S
Sbjct: 767 DFGLTRLLDDFDGTY--ETQGGKI---PIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLS 821
Query: 804 L-MPPHSQIDEDTFDMSLDD 860
P+ ++ S++D
Sbjct: 822 FGDKPYGEMSNQEVMKSIED 841
>BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein.
Length = 504
Score = 51.6 bits (118), Expect = 4e-06
Identities = 34/151 (22%), Positives = 73/151 (48%)
Frame = +3
Query: 276 KMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIE 455
K+ K +KP + + EA +++ + H +V A + +Y+ E ++ G L++
Sbjct: 264 KVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEF--MAKGSLLD 321
Query: 456 KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFG 635
D+ + +++ + I+ + ++ + H D+++ NILV+ V CK+ DFG
Sbjct: 322 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQR-NYTHRDLRAANILVSASLV-CKIADFG 379
Query: 636 VTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
+ +++N +E A + W+APE
Sbjct: 380 LARVIEDNEYTAREGAKFPI-----KWTAPE 405
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/107 (30%), Positives = 62/107 (57%), Gaps = 2/107 (1%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQM 500
+ E ++L+ ++H N++ + F + K L + ME A +L + I+KR + + +
Sbjct: 49 QNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN---SLLEEETI 105
Query: 501 LQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
L V I AL ++HT + ILH D+K+ NIL++ ++ K+ DFG++
Sbjct: 106 LHFFVQILLALHHVHTHL-ILHRDLKTQNILLDKHRMVVKIGDFGIS 151
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/107 (30%), Positives = 62/107 (57%), Gaps = 2/107 (1%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQM 500
+ E ++L+ ++H N++ + F + K L + ME A +L + I+KR + + +
Sbjct: 49 QNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN---SLLEEETI 105
Query: 501 LQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
L V I AL ++HT + ILH D+K+ NIL++ ++ K+ DFG++
Sbjct: 106 LHFFVQILLALHHVHTHL-ILHRDLKTQNILLDKHRMVVKIGDFGIS 151
>AY675319-1|AAT70724.1| 567|Homo sapiens transforming growth
factor, beta receptor II (70/80kDa) protein.
Length = 567
Score = 51.6 bits (118), Expect = 4e-06
Identities = 30/62 (48%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+KS NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLKSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/107 (30%), Positives = 62/107 (57%), Gaps = 2/107 (1%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQM 500
+ E ++L+ ++H N++ + F + K L + ME A +L + I+KR + + +
Sbjct: 49 QNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN---SLLEEETI 105
Query: 501 LQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
L V I AL ++HT + ILH D+K+ NIL++ ++ K+ DFG++
Sbjct: 106 LHFFVQILLALHHVHTHL-ILHRDLKTQNILLDKHRMVVKIGDFGIS 151
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/107 (30%), Positives = 62/107 (57%), Gaps = 2/107 (1%)
Frame = +3
Query: 327 KTEAELLQKMSHLNIVGF-RAFSKGKILYLGME-ACDLSLGDLIEKRVDDDCTPFSPRQM 500
+ E ++L+ ++H N++ + F + K L + ME A +L + I+KR + + +
Sbjct: 49 QNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN---SLLEEETI 105
Query: 501 LQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
L V I AL ++HT + ILH D+K+ NIL++ ++ K+ DFG++
Sbjct: 106 LHFFVQILLALHHVHTHL-ILHRDLKTQNILLDKHRMVVKIGDFGIS 151
>AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 295 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 349
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 350 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 404
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 405 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 458
Query: 807 MPPH 818
PP+
Sbjct: 459 EPPY 462
>AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 310 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 364
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 365 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 419
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 420 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 473
Query: 807 MPPH 818
PP+
Sbjct: 474 EPPY 477
>AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 295 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 349
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 350 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 404
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 405 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 458
Query: 807 MPPH 818
PP+
Sbjct: 459 EPPY 462
>AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 310 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 364
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 365 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 419
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 420 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 473
Query: 807 MPPH 818
PP+
Sbjct: 474 EPPY 477
>AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 295 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 349
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 350 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 404
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 405 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 458
Query: 807 MPPH 818
PP+
Sbjct: 459 EPPY 462
>AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 310 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 364
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 365 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 419
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 420 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 473
Query: 807 MPPH 818
PP+
Sbjct: 474 EPPY 477
>AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3
protein.
Length = 544
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 295 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 349
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 350 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 404
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 405 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 458
Query: 807 MPPH 818
PP+
Sbjct: 459 EPPY 462
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 3/200 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGD 446
A+K L K P + + L+ EA ++ + SH +I+ +K K + + E + D
Sbjct: 654 AIKTL-KDTSPGGQWWNFLR-EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
+ +D P MLQ I+S + YL + +H D+ + NILVN + + CK+
Sbjct: 712 AFLREREDQLVPGQLVAMLQ---GIASGMNYL-SNHNYVHRDLAARNILVNQN-LCCKVS 766
Query: 627 DFGVTLPLDE-NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG+T LD+ +G + E GG + W+APE T + WE++S
Sbjct: 767 DFGLTRLLDDFDGTY--ETQGGKI---PIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLS 821
Query: 804 L-MPPHSQIDEDTFDMSLDD 860
P+ ++ S++D
Sbjct: 822 FGDKPYGEMSNQEVMKSIED 841
>AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3
protein.
Length = 544
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 295 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 349
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 350 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 404
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 405 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 458
Query: 807 MPPH 818
PP+
Sbjct: 459 EPPY 462
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 3/200 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGD 446
A+K L K P + + L+ EA ++ + SH +I+ +K K + + E + D
Sbjct: 654 AIKTL-KDTSPGGQWWNFLR-EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
+ +D P MLQ I+S + YL + +H D+ + NILVN + + CK+
Sbjct: 712 AFLREREDQLVPGQLVAMLQ---GIASGMNYL-SNHNYVHRDLAARNILVNQN-LCCKVS 766
Query: 627 DFGVTLPLDE-NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
DFG+T LD+ +G + E GG + W+APE T + WE++S
Sbjct: 767 DFGLTRLLDDFDGTY--ETQGGKI---PIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLS 821
Query: 804 L-MPPHSQIDEDTFDMSLDD 860
P+ ++ S++D
Sbjct: 822 FGDKPYGEMSNQEVMKSIED 841
>AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3
protein.
Length = 559
Score = 51.6 bits (118), Expect = 4e-06
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 310 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 364
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + AL++LH+ Q++H D+KS NIL+ D + KL
Sbjct: 365 LTDV-VTETC--MDEGQIAAVCRECLQALDFLHSN-QVIHRDIKSDNILLGMDGSV-KLT 419
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 420 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 473
Query: 807 MPPH 818
PP+
Sbjct: 474 EPPY 477
>Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewing's
sarcoma cell line) mRNA encoding open reading frame.
).
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>D14497-1|BAA03387.1| 467|Homo sapiens proto-oncogene protein
protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>CR542284-1|CAG47079.1| 467|Homo sapiens MAP3K8 protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein
protein.
Length = 303
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 3/156 (1%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFRA--FSKGKILYLGMEACDLSLG 443
A K+++ +KP +++ E ++L + + IVGF +S G+I + ME D
Sbjct: 2 ARKLIHLEIKP--AIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEIS-ICMEHMDGGSL 58
Query: 444 DLIEKRVDDDCTPFSPRQML-QVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICK 620
D + K P ++L +V++ + L YL K QI+H D+K NILVN I K
Sbjct: 59 DQVLKEAKR-----IPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEI-K 112
Query: 621 LCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
LCDFGV+ L I N+ + GT ++ APE
Sbjct: 113 LCDFGVSGQL----IDSMANS----FVGTRSYMAPE 140
>BC113566-1|AAI13567.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>BC104833-1|AAI04834.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>AY309013-1|AAP45053.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>AL161651-12|CAI14227.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Frame = +3
Query: 288 KRVKPNKVYTDRLK-TEAELLQKMSHLNIVG-FRAFSKGKILYLGMEACDLSLGDLIEKR 461
KR+ + D+ K ++ E+ H NI + A G+ ++L MEA + G ++EK
Sbjct: 162 KRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEG--GSVLEKL 219
Query: 462 VDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVT 641
+ C P +++ V + L++LH+K +++H D+K NI+ + L DFG++
Sbjct: 220 --ESCGPMREFEIIWVTKHVLKGLDFLHSK-KVIHHDIKPSNIVFMSTKAV--LVDFGLS 274
Query: 642 LPLDENGIFDKENAGGTVYYGTE 710
+ + E+ F K+ G +Y E
Sbjct: 275 VQMTEDVYFPKDLRGTEIYMSPE 297
>AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 51.2 bits (117), Expect = 5e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +3
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 8 FQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS-----RY 60
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 61 VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKYDIWAFGVLMWEIYSL 108
>U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein.
Length = 545
Score = 50.8 bits (116), Expect = 6e-06
Identities = 53/184 (28%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = +3
Query: 270 ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGD 446
A+K +N + +P K + + E ++++ + NIV + ++ G L++ ME L+ G
Sbjct: 297 AIKQMNLQQQPKK---ELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY--LAGGS 351
Query: 447 LIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
L + V + C Q+ V + ALE LH+ Q++H D+KS NIL+ D + KL
Sbjct: 352 LTDV-VTETC--MDEGQIAAVCRECLQALESLHSN-QVIHRDIKSDNILLGMDGSV-KLT 406
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
DFG + E + + GT W APEV T ++ L + EM+
Sbjct: 407 DFGFCAQI------TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEG 460
Query: 807 MPPH 818
PP+
Sbjct: 461 EPPY 464
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 50.8 bits (116), Expect = 6e-06
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
Frame = +3
Query: 246 AGLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRAF-SKGKIL 407
+G ++ P + K ++ +K KV YT++ + EA ++ + H NI+ +K K +
Sbjct: 637 SGRLKLP-SKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPV 695
Query: 408 YLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYN 587
+ E + D ++ D F+ Q++ + I+S ++YL + M +H D+ + N
Sbjct: 696 MIVTEYMENGSLDSFLRKHD---AQFTVIQLVGMLRGIASGMKYL-SDMGYVHRDLAARN 751
Query: 588 ILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTS 767
IL+N + V CK+ DFG++ L+++ GG + W++PE + +
Sbjct: 752 ILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGGKI---PIRWTSPEAIAYRKFTSASDV 807
Query: 768 GHLVSLXWEMMS 803
+ WE+MS
Sbjct: 808 WSYGIVLWEVMS 819
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 226 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 285
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 286 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 343
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 344 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 392
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 307 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 364
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 365 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 413
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 307 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 364
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 365 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 413
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 307 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 364
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 365 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 413
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 307 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 364
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 365 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 413
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 307 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 364
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 365 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 413
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 376
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 377 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 434
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 435 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 483
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 50.8 bits (116), Expect = 6e-06
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
Frame = +3
Query: 246 AGLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRAF-SKGKIL 407
+G ++ P + K ++ +K KV YT++ + EA ++ + H NI+ +K K +
Sbjct: 637 SGRLKLP-SKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPV 695
Query: 408 YLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYN 587
+ E + D ++ D F+ Q++ + I+S ++YL + M +H D+ + N
Sbjct: 696 MIVTEYMENGSLDSFLRKHD---AQFTVIQLVGMLRGIASGMKYL-SDMGYVHRDLAARN 751
Query: 588 ILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTS 767
IL+N + V CK+ DFG++ L+++ GG + W++PE + +
Sbjct: 752 ILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGGKI---PIRWTSPEAIAYRKFTSASDV 807
Query: 768 GHLVSLXWEMMS 803
+ WE+MS
Sbjct: 808 WSYGIVLWEVMS 819
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/176 (23%), Positives = 85/176 (48%), Gaps = 7/176 (3%)
Frame = +3
Query: 222 LQLVRSPRAGLIRSPW------ALKMLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR 383
++LV+ AG W + K+ K +KP + EA L++ + H +V
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 376
Query: 384 AF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQI 560
A ++ + +Y+ E ++ G L++ D+ +++ + I+ + Y+ K I
Sbjct: 377 AVVTREEPIYIITEY--MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYI 434
Query: 561 LHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPE 728
H D+++ N+LV+ + ++CK+ DFG+ +++N +E A + W+APE
Sbjct: 435 -HRDLRAANVLVS-ESLMCKIADFGLARVIEDNEYTAREGAKFPI-----KWTAPE 483
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 50.8 bits (116), Expect = 6e-06
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
Frame = +3
Query: 246 AGLIRSPWALKMLNKRVKPNKV-YTDRLKT----EAELLQKMSHLNIVGFRAF-SKGKIL 407
+G ++ P + K ++ +K KV YT++ + EA ++ + H NI+ +K K +
Sbjct: 637 SGRLKLP-SKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPV 695
Query: 408 YLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYN 587
+ E + D ++ D F+ Q++ + I+S ++YL + M +H D+ + N
Sbjct: 696 MIVTEYMENGSLDSFLRKHD---AQFTVIQLVGMLRGIASGMKYL-SDMGYVHRDLAARN 751
Query: 588 ILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTS 767
IL+N + V CK+ DFG++ L+++ GG + W++PE + +
Sbjct: 752 ILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGGKI---PIRWTSPEAIAYRKFTSASDV 807
Query: 768 GHLVSLXWEMMS 803
+ WE+MS
Sbjct: 808 WSYGIVLWEVMS 819
>AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 172
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +3
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 6 FQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS-----RY 58
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 59 VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 106
>AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +3
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 8 FQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS-----GY 60
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 61 VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 108
>AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 174
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +3
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 8 FQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS-----GY 60
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 61 VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 108
>AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 149
Score = 50.8 bits (116), Expect = 6e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +3
Query: 483 FSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENG 662
F +Q+L++ D+ A+EYL +K Q LH D+ + N LVN V+ K+ DFG++
Sbjct: 5 FQTQQLLEMCKDVCEAMEYLESK-QFLHRDLAARNCLVNDQGVV-KVSDFGLS-----RY 57
Query: 663 IFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMSL 806
+ D E WS PEV ++ ++ L WE+ SL
Sbjct: 58 VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSL 105
>AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase SPAK
protein.
Length = 547
Score = 50.8 bits (116), Expect = 6e-06
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = +3
Query: 288 KRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDL-SLGDLIE 455
KR+ K T D L E + + + SH N+V + +F L+L M+ S+ D+I+
Sbjct: 94 KRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIK 153
Query: 456 ---KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
R + + + ++ L+YLH QI H D+K+ NIL+ D + ++
Sbjct: 154 YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI-HRDLKAGNILLGEDGSV-QIA 211
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
DFGV+ L G + T + GT W APEV R
Sbjct: 212 DFGVSAFLATGGDVTRNKVRKT-FVGTPCWMAPEVMEQVR 250
>AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein.
Length = 363
Score = 50.8 bits (116), Expect = 6e-06
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = +3
Query: 288 KRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDL-SLGDLIE 455
KR+ K T D L E + + + SH N+V + +F L+L M+ S+ D+I+
Sbjct: 92 KRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIK 151
Query: 456 ---KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
R + + + ++ L+YLH QI H D+K+ NIL+ D + ++
Sbjct: 152 YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI-HRDLKAGNILLGEDGSV-QIA 209
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
DFGV+ L G + T + GT W APEV R
Sbjct: 210 DFGVSAFLATGGDVTRNKVRKT-FVGTPCWMAPEVMEQVR 248
>L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 986
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 312 YTDRLK----TEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDC 476
YTD+ + +EA ++ + H NI+ +K K + + E + D ++ D
Sbjct: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR- 717
Query: 477 TPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDE 656
F+ Q++ + I S ++YL + M +H D+ + NILVN + ++CK+ DFG++ L++
Sbjct: 718 --FTVIQLVGMLRGIGSGMKYL-SDMSYVHRDLAARNILVNSN-LVCKVSDFGMSRVLED 773
Query: 657 NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ GG + W+APE + + + WE+MS
Sbjct: 774 DPEAAYTTRGGKI---PIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4
protein.
Length = 986
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 312 YTDRLK----TEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDC 476
YTD+ + +EA ++ + H NI+ +K K + + E + D ++ D
Sbjct: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR- 717
Query: 477 TPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDE 656
F+ Q++ + I S ++YL + M +H D+ + NILVN + ++CK+ DFG++ L++
Sbjct: 718 --FTVIQLVGMLRGIGSGMKYL-SDMSYVHRDLAARNILVNSN-LVCKVSDFGMSRVLED 773
Query: 657 NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ GG + W+APE + + + WE+MS
Sbjct: 774 DPEAAYTTRGGKI---PIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein.
Length = 986
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 312 YTDRLK----TEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDC 476
YTD+ + +EA ++ + H NI+ +K K + + E + D ++ D
Sbjct: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR- 717
Query: 477 TPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDE 656
F+ Q++ + I S ++YL + M +H D+ + NILVN + ++CK+ DFG++ L++
Sbjct: 718 --FTVIQLVGMLRGIGSGMKYL-SDMSYVHRDLAARNILVNSN-LVCKVSDFGMSRVLED 773
Query: 657 NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ GG + W+APE + + + WE+MS
Sbjct: 774 DPEAAYTTRGGKI---PIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein.
Length = 344
Score = 50.4 bits (115), Expect = 8e-06
Identities = 59/192 (30%), Positives = 90/192 (46%), Gaps = 1/192 (0%)
Frame = +3
Query: 159 KITIPPSPFLNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEA 338
K+T+ +L LG GT V+ LVR G +A+K+L K V K TE+
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVI-LVREKATGRY---YAMKILRKEVIIAKDEVAHTVTES 201
Query: 339 ELLQKMSHLNIVGFR-AFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAV 515
+LQ H + + AF L ME + G+L + F+ +
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANG--GELFFHLSRERV--FTEERARFYGA 257
Query: 516 DISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGTV 695
+I SALEYLH++ +++ D+K N++++ D I K+ DFG L + GI D A
Sbjct: 258 EIVSALEYLHSR-DVVYRDIKLENLMLDKDGHI-KITDFG----LCKEGISD--GATMKT 309
Query: 696 YYGTEAWSAPEV 731
+ GT + APEV
Sbjct: 310 FCGTPEYLAPEV 321
>BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein.
Length = 949
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 312 YTDRLK----TEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDC 476
YTD+ + +EA ++ + H NI+ +K K + + E + D ++ D
Sbjct: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR- 717
Query: 477 TPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDE 656
F+ Q++ + I S ++YL + M +H D+ + NILVN + ++CK+ DFG++ L++
Sbjct: 718 --FTVIQLVGMLRGIGSGMKYL-SDMSYVHRDLAARNILVNSN-LVCKVSDFGMSRVLED 773
Query: 657 NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ GG + W+APE + + + WE+MS
Sbjct: 774 DPEAAYTTRGGKI---PIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-like
kinase protein.
Length = 476
Score = 50.4 bits (115), Expect = 8e-06
Identities = 47/159 (29%), Positives = 74/159 (46%), Gaps = 7/159 (4%)
Frame = +3
Query: 288 KRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDL-SLGDLIE 455
KR+ K T D L E + + + SH N+V + +F L+L M+ S+ D+I+
Sbjct: 43 KRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIK 102
Query: 456 ---KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
R + + + ++ L+YLH QI H D+K+ NIL+ D + ++
Sbjct: 103 YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI-HRDLKAGNILLGEDGSV-QIA 160
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA 743
DFGV+ L G + T + GT W APEV A
Sbjct: 161 DFGVSAFLATGGDVTRNKVRKT-FVGTPCWMAPEVMELA 198
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 738
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 739 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 796
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 797 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kinase
protein.
Length = 547
Score = 50.4 bits (115), Expect = 8e-06
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = +3
Query: 288 KRVKPNKVYT--DRLKTEAELLQKMSHLNIVGF-RAFSKGKILYLGMEACDL-SLGDLIE 455
KR+ K T D L E + + + SH N+V + +F L+L M+ S+ D+I+
Sbjct: 94 KRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIK 153
Query: 456 ---KRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLC 626
R + + + ++ L+YLH QI H D+K+ NIL+ D + ++
Sbjct: 154 YIVNRGEHKNGVLEEAIIATIFKEVLEGLDYLHRNGQI-HRDLKAGNILLGEDGSV-QIA 211
Query: 627 DFGVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXAR 746
DFGV+ L G + T + GT W APEV R
Sbjct: 212 DFGVSAFLATGGDVTRNKVRKT-FVGTPCWMAPEVMEQVR 250
>AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein.
Length = 711
Score = 50.4 bits (115), Expect = 8e-06
Identities = 43/169 (25%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 312 YTDRLK----TEAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDC 476
YTD+ + +EA ++ + H NI+ +K K + + E + D ++ D
Sbjct: 384 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR- 442
Query: 477 TPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDE 656
F+ Q++ + I S ++YL + M +H D+ + NILVN + ++CK+ DFG++ L++
Sbjct: 443 --FTVIQLVGMLRGIGSGMKYL-SDMSYVHRDLAARNILVNSN-LVCKVSDFGMSRVLED 498
Query: 657 NGIFDKENAGGTVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ GG + W+APE + + + WE+MS
Sbjct: 499 DPEAAYTTRGGKI---PIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 544
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 50.4 bits (115), Expect = 8e-06
Identities = 38/158 (24%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H N+V ++GK + + +E + D ++ D F+ Q++ +
Sbjct: 684 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ---FTVIQLVGM 740
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
I++ + YL M +H D+ + NILVN + ++CK+ DFG++ ++++ GG
Sbjct: 741 LRGIAAGMRYL-ADMGYVHRDLAARNILVNSN-LVCKVSDFGLSRVIEDDPEAVYTTTGG 798
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE+MS
Sbjct: 799 KI---PVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 833
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine kinase
protein.
Length = 1037
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H NI+ +K K + + E + D K+ D F+ Q++ +
Sbjct: 724 EASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ---FTVIQLVGM 780
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
IS+ ++YL + M +H D+ + NIL+N + V CK+ DFG++ L+++ GG
Sbjct: 781 LRGISAGMKYL-SDMGYVHRDLAARNILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGG 838
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE++S
Sbjct: 839 KI---PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 873
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 50.0 bits (114), Expect = 1e-05
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 7/247 (2%)
Frame = +3
Query: 108 MTEFQTPQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALK 278
M + P+ +K D +T P L KLG G+ SV + + ++ A+K
Sbjct: 1 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVV----AIK 56
Query: 279 MLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLI 452
+ P + + E ++Q+ +V + ++ K L++ ME C S+ D+I
Sbjct: 57 QV-----PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 111
Query: 453 EKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDF 632
R ++ + LEYLH M+ +H D+K+ NIL+N + KL DF
Sbjct: 112 RLRNKT----LIEDEIATILKSTLKGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADF 165
Query: 633 GVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSL 806
GV L + K N TV GT W APEV V ++ S + S+ EM
Sbjct: 166 GVAGQLTDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITSI--EMAEG 217
Query: 807 MPPHSQI 827
PP++ I
Sbjct: 218 KPPYADI 224
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 50.0 bits (114), Expect = 1e-05
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 7/247 (2%)
Frame = +3
Query: 108 MTEFQTPQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALK 278
M + P+ +K D +T P L KLG G+ SV + + ++ A+K
Sbjct: 1 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVV----AIK 56
Query: 279 MLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLI 452
+ P + + E ++Q+ +V + ++ K L++ ME C S+ D+I
Sbjct: 57 QV-----PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 111
Query: 453 EKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDF 632
R ++ + LEYLH M+ +H D+K+ NIL+N + KL DF
Sbjct: 112 RLRNKT----LIEDEIATILKSTLKGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADF 165
Query: 633 GVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSL 806
GV L + K N TV GT W APEV V ++ S + S+ EM
Sbjct: 166 GVAGQLTDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITSI--EMAEG 217
Query: 807 MPPHSQI 827
PP++ I
Sbjct: 218 KPPYADI 224
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H NI+ +K K + + E + D K+ D F+ Q++ +
Sbjct: 678 EASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ---FTVIQLVGM 734
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
IS+ ++YL + M +H D+ + NIL+N + V CK+ DFG++ L+++ GG
Sbjct: 735 LRGISAGMKYL-SDMGYVHRDLAARNILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGG 792
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE++S
Sbjct: 793 KI---PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 827
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 68/241 (28%), Positives = 110/241 (45%), Gaps = 7/241 (2%)
Frame = +3
Query: 126 PQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRV 296
P++ +K D D +T P L KLG G+ SV + + ++ A+K +
Sbjct: 10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIV----AIKQV---- 61
Query: 297 KPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLIEKRVDD 470
P + + E ++Q+ ++V + ++ K L++ ME C S+ D+I R +
Sbjct: 62 -PVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NK 119
Query: 471 DCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPL 650
T +LQ + LEYLH M+ +H D+K+ NIL+N + KL DFGV L
Sbjct: 120 TLTEDEIATILQSTL---KGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADFGVAGQL 174
Query: 651 DENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSLMPPHSQ 824
+ K N TV GT APEV V ++ S + ++ EM PP++
Sbjct: 175 TDT--MAKRN---TV-IGTPFLMAPEVIQEIGYNCVADIWSLGITAI--EMAEGKPPYAD 226
Query: 825 I 827
I
Sbjct: 227 I 227
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 50.0 bits (114), Expect = 1e-05
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 7/247 (2%)
Frame = +3
Query: 108 MTEFQTPQKSIKPFDNDKITIPPSPF---LNKLGYGTGVSVLQLVRSPRAGLIRSPWALK 278
M + P+ +K D +T P L KLG G+ SV + + ++ A+K
Sbjct: 1 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVV----AIK 56
Query: 279 MLNKRVKPNKVYTDRLKTEAELLQKMSHLNIVGFR-AFSKGKILYLGMEACDL-SLGDLI 452
+ P + + E ++Q+ +V + ++ K L++ ME C S+ D+I
Sbjct: 57 QV-----PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII 111
Query: 453 EKRVDDDCTPFSPRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDF 632
R ++ + LEYLH M+ +H D+K+ NIL+N + KL DF
Sbjct: 112 RLRNKT----LIEDEIATILKSTLKGLEYLHF-MRKIHRDIKAGNILLNTE-GHAKLADF 165
Query: 633 GVTLPLDENGIFDKENAGGTVYYGTEAWSAPEVXTXA--RSVTELTSGHLVSLXWEMMSL 806
GV L + K N TV GT W APEV V ++ S + S+ EM
Sbjct: 166 GVAGQLTDT--MAKRN---TV-IGTPFWMAPEVIQEIGYNCVADIWSLGITSI--EMAEG 217
Query: 807 MPPHSQI 827
PP++ I
Sbjct: 218 KPPYADI 224
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 1/158 (0%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAF-SKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQV 509
EA ++ + H NI+ +K K + + E + D K+ D F+ Q++ +
Sbjct: 738 EASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ---FTVIQLVGM 794
Query: 510 AVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGG 689
IS+ ++YL + M +H D+ + NIL+N + V CK+ DFG++ L+++ GG
Sbjct: 795 LRGISAGMKYL-SDMGYVHRDLAARNILINSNLV-CKVSDFGLSRVLEDDPEAAYTTRGG 852
Query: 690 TVYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
+ W+APE + + + WE++S
Sbjct: 853 KI---PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 887
>X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein.
Length = 360
Score = 49.6 bits (113), Expect = 1e-05
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 3/154 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
LN++G GT ++ R + I ALK + + + + L+ E LL ++ H
Sbjct: 42 LNRIGEGT-YGIVYRARDTQTDEIV---ALKKVRMDKEKDGIPISSLR-EITLLLRLRHP 96
Query: 366 NIVGFRAFSKGKIL---YLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
NIV + G L +L M C+ L L+E TPFS Q+ + + + L+
Sbjct: 97 NIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMP----TPFSEAQVKCIVLQVLRGLQ 152
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGV 638
YLH I+H D+K N+L+ D K DFG+
Sbjct: 153 YLHRNF-IIHRDLKVSNLLMT-DKGCVKTADFGL 184
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/157 (26%), Positives = 74/157 (47%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVA 512
E ++ KM H N+V + LY+ ME +S G+L+ + Q+LQ +
Sbjct: 276 ETAVMTKMQHENLVRLLGVILHQGLYIVME--HVSKGNLVNFLRTRGRALVNTAQLLQFS 333
Query: 513 VDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGT 692
+ ++ +EYL +K +++H D+ + NILV+ D ++ K+ DFG+ + G+ D
Sbjct: 334 LHVAEGMEYLESK-KLVHRDLAARNILVSED-LVAKVSDFGLA-KAERKGL-DSSRL--- 386
Query: 693 VYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
W+APE + ++ L WE+ S
Sbjct: 387 ----PVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/157 (26%), Positives = 74/157 (47%)
Frame = +3
Query: 333 EAELLQKMSHLNIVGFRAFSKGKILYLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVA 512
E ++ KM H N+V + LY+ ME +S G+L+ + Q+LQ +
Sbjct: 276 ETAVMTKMQHENLVRLLGVILHQGLYIVME--HVSKGNLVNFLRTRGRALVNTAQLLQFS 333
Query: 513 VDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIFDKENAGGT 692
+ ++ +EYL +K +++H D+ + NILV+ D ++ K+ DFG+ + G+ D
Sbjct: 334 LHVAEGMEYLESK-KLVHRDLAARNILVSED-LVAKVSDFGLA-KAERKGL-DSSRL--- 386
Query: 693 VYYGTEAWSAPEVXTXARSVTELTSGHLVSLXWEMMS 803
W+APE + ++ L WE+ S
Sbjct: 387 ----PVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS 419
>L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kinase
protein.
Length = 314
Score = 49.6 bits (113), Expect = 1e-05
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 3/154 (1%)
Frame = +3
Query: 186 LNKLGYGTGVSVLQLVRSPRAGLIRSPWALKMLNKRVKPNKVYTDRLKTEAELLQKMSHL 365
LN++G GT ++ R + I ALK + + + + L+ E LL ++ H
Sbjct: 13 LNRIGEGT-YGIVYRARDTQTDEIV---ALKKVRMDKEKDGIPISSLR-EITLLLRLRHP 67
Query: 366 NIVGFRAFSKGKIL---YLGMEACDLSLGDLIEKRVDDDCTPFSPRQMLQVAVDISSALE 536
NIV + G L +L M C+ L L+E TPFS Q+ + + + L+
Sbjct: 68 NIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMP----TPFSEAQVKCIVLQVLRGLQ 123
Query: 537 YLHTKMQILHGDMKSYNILVNGDFVICKLCDFGV 638
YLH I+H D+K N+L+ D K DFG+
Sbjct: 124 YLHRNF-IIHRDLKVSNLLMT-DKGCVKTADFGL 155
>D50683-1|BAA09332.1| 567|Homo sapiens TGF-betaIIR alpha protein.
Length = 567
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/62 (46%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +3
Query: 549 KMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDEN-GIFDKENAGGTVYYGTEAWSAP 725
KM I+H D+ S NILV D C LCDFG++L LD + D N+G GT + AP
Sbjct: 372 KMPIVHRDLNSSNILVKNDLTCC-LCDFGLSLRLDPTLSVDDLANSG---QVGTARYMAP 427
Query: 726 EV 731
EV
Sbjct: 428 EV 429
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 3/137 (2%)
Frame = +3
Query: 318 DRLKTEAELLQKMSHLNIVGFRAFSKGKI---LYLGMEACDLSLGDLIEKRVDDDCTPFS 488
+R+ E +L+K+ H+N+V LYL + L G ++E D PFS
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDL--LRKGPVMEVPCDK---PFS 248
Query: 489 PRQMLQVAVDISSALEYLHTKMQILHGDMKSYNILVNGDFVICKLCDFGVTLPLDENGIF 668
Q D+ LEYLH + +I+H D+K N+L+ GD K+ DFGV+ + N
Sbjct: 249 EEQARLYLRDVILGLEYLHCQ-KIVHRDIKPSNLLL-GDDGHVKIADFGVSNQFEGNDAQ 306
Query: 669 DKENAGGTVYYGTEAWS 719
AG + EA S
Sbjct: 307 LSSTAGTPAFMAPEAIS 323
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 133,918,414
Number of Sequences: 237096
Number of extensions: 3035718
Number of successful extensions: 7008
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6303
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6683
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11270645666
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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