Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP20_F_F15
(872 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 79 3e-14
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 78 5e-14
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 78 5e-14
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 78 5e-14
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 78 5e-14
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 78 5e-14
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 78 5e-14
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 78 5e-14
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 78 5e-14
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 78 5e-14
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 78 5e-14
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 78 5e-14
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 78 5e-14
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 78 5e-14
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 78 5e-14
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 76 2e-13
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 76 2e-13
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 76 2e-13
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 76 2e-13
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 76 2e-13
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 76 2e-13
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 76 2e-13
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 76 2e-13
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 73 1e-12
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 73 1e-12
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 73 1e-12
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 73 1e-12
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 70 1e-11
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 69 2e-11
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 69 2e-11
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 69 2e-11
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 69 2e-11
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 69 2e-11
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 69 2e-11
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 69 2e-11
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 69 2e-11
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 69 2e-11
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 69 2e-11
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 69 3e-11
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 68 4e-11
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 68 4e-11
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 68 4e-11
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 68 4e-11
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 68 5e-11
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 68 5e-11
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 68 5e-11
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 68 5e-11
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 68 5e-11
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 68 5e-11
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 68 5e-11
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 68 5e-11
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 68 5e-11
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 68 5e-11
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 67 9e-11
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 67 9e-11
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 67 9e-11
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 67 9e-11
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 67 9e-11
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 67 9e-11
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 67 9e-11
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 67 9e-11
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 67 9e-11
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 67 9e-11
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 67 9e-11
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 67 9e-11
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 67 9e-11
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 67 9e-11
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 66 1e-10
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 66 1e-10
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 66 2e-10
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 66 2e-10
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 66 2e-10
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 66 2e-10
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 66 2e-10
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 66 2e-10
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 66 2e-10
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 66 2e-10
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 66 2e-10
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 66 2e-10
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 66 2e-10
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 66 2e-10
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 64 6e-10
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 62 3e-09
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 60 1e-08
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 60 1e-08
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 56 1e-07
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 38 0.036
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 33 1.8
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 31 7.2
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 31 7.2
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 31 7.2
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 78.6 bits (185), Expect = 3e-14
Identities = 36/93 (38%), Positives = 60/93 (64%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
L++ P +K IA +HG++PAQIL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD
Sbjct: 232 LIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMD 291
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ +F + H +YPFHIE
Sbjct: 292 NILSLNRNLRLAMFPI-----TKNHNDYPFHIE 319
Score = 66.9 bits (156), Expect = 9e-11
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 18/123 (14%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGFHCD-PETLT-----------PRVKS----DGEYD 148
T R+ LK L+L+Y+DLYLIH P GF PE + PRV+ +
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMV 141
Query: 149 VDMDTNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYF 322
+ DT+ L W+ ME GL++N+G+SNFN EQ+ ++ + KP Q+E H Y
Sbjct: 142 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYL 201
Query: 323 QQQ 331
Q+
Sbjct: 202 TQK 204
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 70.5 bits (165), Expect = 7e-12
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPIGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 70.1 bits (164), Expect = 1e-11
Identities = 44/101 (43%), Positives = 54/101 (53%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFRPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKI-SKSS-TIKPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I SK KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 64.1 bits (149), Expect = 6e-10
Identities = 41/101 (40%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTRAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/115 (37%), Positives = 64/115 (55%)
Frame = +1
Query: 391 VVPELKIISLPNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKST 570
VV + P+ A+ LL P++K IA KH +T AQ+L+ F +Q+ +VVIPKS
Sbjct: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265
Query: 571 SEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ R+ EN ++DFELS+ +M L L + R+ + L H +YPFH E
Sbjct: 266 TPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPFHEE 315
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 153
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 154 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 194
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 75.8 bits (178), Expect = 2e-13
Identities = 41/101 (40%), Positives = 59/101 (58%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQR 205
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +E
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKALEALVA 152
Query: 206 EGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+GL++ LGLSNFN QI I ++++P VLQVE H Y Q
Sbjct: 153 KGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/67 (47%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P V +A+K+GR+PAQILL + VQ+KV+ IPKS + R+ +N+ ++DF S EM
Sbjct: 228 LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMK 287
Query: 637 LLKKLDK 657
L L+K
Sbjct: 288 QLNALNK 294
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/100 (41%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L++L+LDYVDLY+I VP F E + PR +G++ + +N W+ ME C+ GL
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDE-IYPR-DENGKW-LYHKSNLCATWEAMEACKDAGL 162
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++LG+SNFN Q+ I + KP QVE H YF Q
Sbjct: 163 VKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/104 (38%), Positives = 59/104 (56%)
Frame = +1
Query: 424 NTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNI 603
N + S LL + + ++ +T AQI+L F +Q+ VVVIPKS + R++EN I
Sbjct: 227 NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQI 286
Query: 604 YDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+DF L+ EM ++ L+K + R L W+ HPEYPFH E
Sbjct: 287 FDFSLTEEEMKDIEALNK--NVRFVELLMWR---DHPEYPFHDE 325
Score = 33.9 bits (74), Expect = 0.77
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 336 LRKFCTDNDIVVTAYAPLGS 395
L KFC +DIV+TAY+PLG+
Sbjct: 205 LLKFCQQHDIVITAYSPLGT 224
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/100 (41%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L++L+LDYVDLY+I VP F E + PR +G++ + +N W+ ME C+ GL
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDE-IYPR-DENGKW-LYHKSNLCATWEAMEACKDAGL 162
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++LG+SNFN Q+ I + KP QVE H YF Q
Sbjct: 163 VKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/104 (38%), Positives = 59/104 (56%)
Frame = +1
Query: 424 NTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNI 603
N + S LL + + ++ +T AQI+L F +Q+ VVVIPKS + R++EN I
Sbjct: 227 NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQI 286
Query: 604 YDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+DF L+ EM ++ L+K + R L W+ HPEYPFH E
Sbjct: 287 FDFSLTEEEMKDIEALNK--NVRFVELLMWR---DHPEYPFHDE 325
Score = 33.9 bits (74), Expect = 0.77
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 336 LRKFCTDNDIVVTAYAPLGS 395
L KFC +DIV+TAY+PLG+
Sbjct: 205 LLKFCQQHDIVITAYSPLGT 224
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/100 (41%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L++L+LDYVDLY+I VP F E + PR +G++ + +N W+ ME C+ GL
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDE-IYPR-DENGKW-LYHKSNLCATWEAMEACKDAGL 162
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++LG+SNFN Q+ I + KP QVE H YF Q
Sbjct: 163 VKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/104 (38%), Positives = 59/104 (56%)
Frame = +1
Query: 424 NTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNI 603
N + S LL + + ++ +T AQI+L F +Q+ VVVIPKS + R++EN I
Sbjct: 227 NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQI 286
Query: 604 YDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+DF L+ EM ++ L+K + R L W+ HPEYPFH E
Sbjct: 287 FDFSLTEEEMKDIEALNK--NVRFVELLMWR---DHPEYPFHDE 325
Score = 33.9 bits (74), Expect = 0.77
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 336 LRKFCTDNDIVVTAYAPLGS 395
L KFC +DIV+TAY+PLG+
Sbjct: 205 LLKFCQQHDIVITAYSPLGT 224
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 72.9 bits (171), Expect = 1e-12
Identities = 41/100 (41%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L++L+LDYVDLY+I VP F E + PR +G++ + +N W+ ME C+ GL
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDE-IYPR-DENGKW-LYHKSNLCATWEAMEACKDAGL 162
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++LG+SNFN Q+ I + KP QVE H YF Q
Sbjct: 163 VKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202
Score = 72.9 bits (171), Expect = 1e-12
Identities = 40/104 (38%), Positives = 59/104 (56%)
Frame = +1
Query: 424 NTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNI 603
N + S LL + + ++ +T AQI+L F +Q+ VVVIPKS + R++EN I
Sbjct: 227 NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQI 286
Query: 604 YDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+DF L+ EM ++ L+K + R L W+ HPEYPFH E
Sbjct: 287 FDFSLTEEEMKDIEALNK--NVRFVELLMWR---DHPEYPFHDE 325
Score = 33.9 bits (74), Expect = 0.77
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 336 LRKFCTDNDIVVTAYAPLGS 395
L KFC +DIV+TAY+PLG+
Sbjct: 205 LLKFCQQHDIVITAYSPLGT 224
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 69.7 bits (163), Expect = 1e-11
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
L L+LDY+DLYLIH P GF E + G V DTN L W ME EGL
Sbjct: 94 LSDLKLDYLDLYLIHWPTGFKPGKEFFP--LDESGNV-VPSDTNILDTWAAMEELVDEGL 150
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
++ +G+SNFN Q+ I + KP V Q+E H Y Q+
Sbjct: 151 VKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQE 191
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C IVVTAY+PLGSP
Sbjct: 184 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 213
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 295 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 322
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 220 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 279
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 280 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 307
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 88 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 143
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 144 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 184
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 233 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 292
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 293 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 320
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 101 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 156
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 157 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 197
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 295 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 322
Score = 66.1 bits (154), Expect = 2e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 69.3 bits (162), Expect = 2e-11
Identities = 32/79 (40%), Positives = 52/79 (65%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEMDLLKKLDK 657
++DF+LS EM ++ ++
Sbjct: 276 VFDFKLSDEEMAIILSFNR 294
Score = 61.3 bits (142), Expect = 4e-09
Identities = 39/105 (37%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK +L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDPKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 295 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 322
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 69.3 bits (162), Expect = 2e-11
Identities = 36/93 (38%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 295 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 322
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 68.9 bits (161), Expect = 2e-11
Identities = 28/67 (41%), Positives = 49/67 (73%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
L++ P +K IA +HG++PAQIL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD
Sbjct: 232 LIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMD 291
Query: 637 LLKKLDK 657
+ L++
Sbjct: 292 NILSLNR 298
Score = 66.9 bits (156), Expect = 9e-11
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 18/123 (14%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGFHCD-PETLT-----------PRVKS----DGEYD 148
T R+ LK L+L+Y+DLYLIH P GF PE + PRV+ +
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMV 141
Query: 149 VDMDTNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYF 322
+ DT+ L W+ ME GL++N+G+SNFN EQ+ ++ + KP Q+E H Y
Sbjct: 142 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYL 201
Query: 323 QQQ 331
Q+
Sbjct: 202 TQK 204
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 68.9 bits (161), Expect = 2e-11
Identities = 40/105 (38%), Positives = 62/105 (59%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEMDLLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
++DF+LS EM + L + R + L +E +YPF+ E
Sbjct: 276 VFDFKLSDEEMATI--LSFNRNWRACNVLQSSHLE---DYPFNAE 315
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK L+L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDLKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 68.9 bits (161), Expect = 2e-11
Identities = 28/67 (41%), Positives = 49/67 (73%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
L++ P +K IA +HG++PAQIL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD
Sbjct: 232 LIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMD 291
Query: 637 LLKKLDK 657
+ L++
Sbjct: 292 NILSLNR 298
Score = 66.9 bits (156), Expect = 9e-11
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 18/123 (14%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGFHCD-PETLT-----------PRVKS----DGEYD 148
T R+ LK L+L+Y+DLYLIH P GF PE + PRV+ +
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMV 141
Query: 149 VDMDTNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYF 322
+ DT+ L W+ ME GL++N+G+SNFN EQ+ ++ + KP Q+E H Y
Sbjct: 142 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYL 201
Query: 323 QQQ 331
Q+
Sbjct: 202 TQK 204
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 68.5 bits (160), Expect = 3e-11
Identities = 36/93 (38%), Positives = 58/93 (62%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L+ R + ++ V HP+YPF E
Sbjct: 295 VLDGLN-----RNYRYVVMDFVMDHPDYPFSDE 322
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/101 (41%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLCATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 68.1 bits (159), Expect = 4e-11
Identities = 32/71 (45%), Positives = 48/71 (67%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEM 633
++DF+LS EM
Sbjct: 276 VFDFKLSDEEM 286
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK L+L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDLKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 68.1 bits (159), Expect = 4e-11
Identities = 32/71 (45%), Positives = 48/71 (67%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEM 633
++DF+LS EM
Sbjct: 276 VFDFKLSDEEM 286
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK L+L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDLKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 68.1 bits (159), Expect = 4e-11
Identities = 32/71 (45%), Positives = 48/71 (67%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEM 633
++DF+LS EM
Sbjct: 276 VFDFKLSDEEM 286
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK L+L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDLKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 68.1 bits (159), Expect = 4e-11
Identities = 32/71 (45%), Positives = 48/71 (67%)
Frame = +1
Query: 421 PNTTIARIRSLXLLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMN 600
P+ A+ LL P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+
Sbjct: 216 PDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQ 275
Query: 601 IYDFELSAPEM 633
++DF+LS EM
Sbjct: 276 VFDFKLSDEEM 286
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +2
Query: 23 YREFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQ 202
+ + LK L+L Y+D+YLIH P GF + L P K D + L W+ ME
Sbjct: 93 FEKTLKDLKLSYLDVYLIHWPQGFKSGDD-LFP--KDDKGNAIGGKATFLDAWEAMEELV 149
Query: 203 REGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
EGL++ LG+SNF+ QI K+ + KP QVE H Y Q+
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Score = 30.3 bits (65), Expect = 9.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGSP 398
C L ++C I VTAY+PLGSP
Sbjct: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSP 216
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 105 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 161
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 162 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 201
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 237 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 296
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 297 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 324
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 35/93 (37%), Positives = 57/93 (61%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH +TPA I L + +Q+ VVV+ KS +E R+REN+ +++F+L++ +M
Sbjct: 235 LLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+L L++ + FL HP+YPF E
Sbjct: 295 VLDGLNRNYRYVVMDFLM-----DHPDYPFSDE 322
Score = 65.3 bits (152), Expect = 3e-10
Identities = 42/101 (41%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTI-WKEMELCQREG 211
LK L+LDYVDLYL+H P ET P+ D V DT L+ W+ ME C+ G
Sbjct: 103 LKKLQLDYVDLYLLHFPMALK-PGETPLPK---DENGKVIFDTVDLSATWEVMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
L +++G+SNFN Q+ I + KP QVE H Y Q
Sbjct: 159 LAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQ 199
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 62.5 bits (145), Expect = 2e-09
Identities = 33/93 (35%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ +S +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLARSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 67.7 bits (158), Expect = 5e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 40/100 (40%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMELCQREGL 214
LK +LDYVDLYLIH P E L+P +G+ D+ + T W+ ME C+ GL
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLK-PGEELSP-TDENGKVIFDI-VDLCTTWEAMEKCKDAGL 159
Query: 215 IRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+++G+SNFN Q+ I + KP QVE H YF +
Sbjct: 160 AKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNR 199
Score = 63.7 bits (148), Expect = 8e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L+A +M
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ LD R + HP YP+ E
Sbjct: 295 AIDGLD-----RNLHYFNSDSFASHPNYPYSDE 322
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 86 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 141
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 142 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 183
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 218 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 277
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 278 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 305
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 176 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 204
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 69 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 124
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 125 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 166
Score = 44.8 bits (101), Expect = 4e-04
Identities = 22/47 (46%), Positives = 32/47 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENM 597
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+
Sbjct: 201 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNV 247
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 159 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 187
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 9e-11
Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ +E C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAVEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN Q+ I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 66.5 bits (155), Expect = 1e-10
Identities = 35/93 (37%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P +K IA KH R+P Q+ L + +Q+ VVV+ KS S+ R++EN I+DFEL+ +M
Sbjct: 217 LLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMK 276
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ L + HP +PF E
Sbjct: 277 AIDGLNRN--------LRYDNAANHPYFPFSEE 301
Score = 35.5 bits (78), Expect = 0.25
Identities = 21/54 (38%), Positives = 30/54 (55%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMEL 196
LK L DYVDL++IHVPF + L P+ D ++ ++T L E+EL
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPK---DASGEIILETVELCDTWELEL 156
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 66.5 bits (155), Expect = 1e-10
Identities = 35/93 (37%), Positives = 53/93 (56%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P +K IA KH R+P Q+ L + +Q+ VVV+ KS S+ R++EN I+DFEL+ +M
Sbjct: 217 LLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMK 276
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ L + HP +PF E
Sbjct: 277 AIDGLNRN--------LRYDNAANHPYFPFSEE 301
Score = 35.5 bits (78), Expect = 0.25
Identities = 21/54 (38%), Positives = 30/54 (55%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEMEL 196
LK L DYVDL++IHVPF + L P+ D ++ ++T L E+EL
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPK---DASGEIILETVELCDTWELEL 156
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTIK--PQVLQVELHAYFQQQ 331
L +++G+SNFN + I +K P QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQR 200
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/67 (40%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDK 657
+ L++
Sbjct: 295 AIDGLNR 301
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 65.7 bits (153), Expect = 2e-10
Identities = 28/55 (50%), Positives = 42/55 (76%)
Frame = +1
Query: 469 PQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEM 633
P++KEIA KH +T AQ+L+ F +Q+ V+VIPKS + R+ EN+ ++DF+LS EM
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 55
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 116 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 171
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 172 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 213
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 206 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 234
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQQ 331
L +++G+SNFN + I + KP QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR 200
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/93 (36%), Positives = 56/93 (60%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDKGESGRIFSFLFWKGVEKHPEYPFHIE 735
+ L++ + R + + G P YPF E
Sbjct: 295 AIDGLNR--NVRYLTLDIFAG---PPNYPFSDE 322
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/102 (39%), Positives = 53/102 (51%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDY DLYLIH P E + P+ D + DT L W+ ME C+ G
Sbjct: 103 LKNLQLDYADLYLIHFPVSVKPGEEVI-PK---DENGKILFDTVDLCATWEAMEKCKDAG 158
Query: 212 LIRNLGLSNFNEEQIRKISKSSTIK--PQVLQVELHAYFQQQ 331
L +++G+SNFN + I +K P QVE H YF Q+
Sbjct: 159 LAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQR 200
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/67 (40%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 637 LLKKLDK 657
+ L++
Sbjct: 295 AIDGLNR 301
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 193 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 62.1 bits (144), Expect = 3e-09
Identities = 38/102 (37%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHL-TIWKEMELCQREG 211
LK L+LDYVDLYLIH P E + D + DT L W+ +E C+
Sbjct: 100 LKNLQLDYVDLYLIHFPVSVKPGEEV----IPKDENGKILFDTVDLCATWEAVEKCKDAE 155
Query: 212 LIRNLGLSNFNEEQIRKI--SKSSTIKPQVLQVELHAYFQQQ 331
L +++G+SNFN + I +KP QVE H YF Q+
Sbjct: 156 LAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQR 197
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/67 (40%), Positives = 46/67 (68%)
Frame = +1
Query: 457 LLNLPQVKEIADKHGRTPAQILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMD 636
LL P + +A KH RTPA I L + +Q+ VVV+ KS +E R+R+N+ +++F+L++ EM
Sbjct: 232 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 291
Query: 637 LLKKLDK 657
+ L++
Sbjct: 292 AIDGLNR 298
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 309 CMRISNNRXLRKFCTDNDIVVTAYAPLGS 395
C N R L FC DIV+ AY+ LGS
Sbjct: 190 CHPYFNQRKLLDFCKSKDIVLVAYSALGS 218
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 16/121 (13%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGFHCD-PETLT-----------PRVKS----DGEYD 148
T R+ LK L+L+Y+DLYLIH P GF PE + PRV+ +
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMV 141
Query: 149 VDMDTNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+ DT+ L W+ ME GL++N+G+SNFN EQ+ ++ ++ + L ++ FQ
Sbjct: 142 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQI 201
Query: 329 Q 331
Q
Sbjct: 202 Q 202
Score = 57.6 bits (133), Expect = 5e-08
Identities = 27/74 (36%), Positives = 45/74 (60%)
Frame = +1
Query: 514 QILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFW 693
QIL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD + L++ +F
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPI--- 250
Query: 694 KGVEKHPEYPFHIE 735
+ H +YPFHIE
Sbjct: 251 --TKNHKDYPFHIE 262
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 60.1 bits (139), Expect = 1e-08
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 16/121 (13%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGFHCD-PETLT-----------PRVKS----DGEYD 148
T R+ LK L+L+Y+DLYLIH P GF PE + PRV+ +
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMV 141
Query: 149 VDMDTNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTIKPQVLQVELHAYFQQ 328
+ DT+ L W+ ME GL++N+G+SNFN EQ+ ++ ++ + L ++ FQ
Sbjct: 142 IPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQI 201
Query: 329 Q 331
Q
Sbjct: 202 Q 202
Score = 47.6 bits (108), Expect = 6e-05
Identities = 19/48 (39%), Positives = 34/48 (70%)
Frame = +1
Query: 514 QILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMDLLKKLDK 657
QIL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD + L++
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNR 241
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 56.4 bits (130), Expect = 1e-07
Identities = 26/74 (35%), Positives = 45/74 (60%)
Frame = +1
Query: 514 QILLNFLVQQKVVVIPKSTSEHRLRENMNIYDFELSAPEMDLLKKLDKGESGRIFSFLFW 693
+IL+ F +Q+ V+VIP S + ++EN+ ++DFEL+ +MD + L++ +F
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPI--- 209
Query: 694 KGVEKHPEYPFHIE 735
+ H +YPFHIE
Sbjct: 210 --TKNHKDYPFHIE 221
Score = 36.3 bits (80), Expect = 0.14
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 17 THYREFLKILELDYVDLYLIHVPFGF 94
T R+ LK L+L+Y+DLYLIH P GF
Sbjct: 82 TACRKSLKALKLNYLDLYLIHWPMGF 107
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = +2
Query: 161 TNHLTIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTI--KPQVLQVELHAYFQQ 328
+N W+ ME C+ GL+++LG+SNFN Q+ I + KP QVE H YF Q
Sbjct: 23 SNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 80
Score = 33.9 bits (74), Expect = 0.77
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +3
Query: 336 LRKFCTDNDIVVTAYAPLGS 395
L KFC +DIV+TAY+PLG+
Sbjct: 83 LLKFCQQHDIVITAYSPLGT 102
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 38.3 bits (85), Expect = 0.036
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +2
Query: 173 TIWKEMELCQREGLIRNLGLSNFNEEQIRKISKSSTIK 286
T W+ ME C+ GL +++G+SNFN Q+ I +K
Sbjct: 23 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 32.7 bits (71), Expect = 1.8
Identities = 19/55 (34%), Positives = 30/55 (54%)
Frame = +2
Query: 26 REFLKILELDYVDLYLIHVPFGFHCDPETLTPRVKSDGEYDVDMDTNHLTIWKEM 190
R+ L L+L+Y+DLYL+H P+ F P+ +DG D T++ WK +
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPF-PK-NADGTICYD-STHYKETWKAL 147
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 30.7 bits (66), Expect = 7.2
Identities = 13/18 (72%), Positives = 15/18 (83%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPF 88
LK L DYVDL++IHVPF
Sbjct: 106 LKKLGPDYVDLFIIHVPF 123
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 30.7 bits (66), Expect = 7.2
Identities = 13/18 (72%), Positives = 15/18 (83%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPF 88
LK L DYVDL++IHVPF
Sbjct: 106 LKKLGPDYVDLFIIHVPF 123
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 30.7 bits (66), Expect = 7.2
Identities = 13/18 (72%), Positives = 15/18 (83%)
Frame = +2
Query: 35 LKILELDYVDLYLIHVPF 88
LK L DYVDL++IHVPF
Sbjct: 106 LKKLGPDYVDLFIIHVPF 123
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,728,688
Number of Sequences: 237096
Number of extensions: 2810204
Number of successful extensions: 5366
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 4897
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5236
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11104084400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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