Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP20_F_F06
(950 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 163 1e-39
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 163 1e-39
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 163 1e-39
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 163 1e-39
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 163 1e-39
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 163 1e-39
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 145 2e-34
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 144 4e-34
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 144 4e-34
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 144 4e-34
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 144 4e-34
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 144 4e-34
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 144 4e-34
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 144 4e-34
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 144 4e-34
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 142 1e-33
BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a prote... 142 1e-33
AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant ... 142 1e-33
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 141 3e-33
U31601-1|AAC50226.1| 1094|Homo sapiens JAK3B protein. 138 4e-32
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 138 4e-32
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 138 4e-32
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 136 1e-31
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 136 1e-31
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 136 1e-31
AB219242-1|BAE02826.1| 1141|Homo sapiens janus kinase 1 protein. 136 1e-31
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 136 1e-31
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 135 2e-31
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 135 2e-31
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 135 2e-31
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 135 2e-31
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 134 3e-31
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 134 3e-31
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 133 8e-31
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 133 8e-31
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 133 8e-31
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 133 8e-31
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 133 8e-31
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 133 8e-31
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 133 8e-31
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 132 2e-30
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 132 2e-30
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 132 2e-30
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 132 2e-30
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 132 2e-30
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 131 4e-30
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 131 4e-30
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 131 4e-30
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 131 4e-30
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 131 4e-30
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 131 4e-30
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 130 5e-30
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 130 5e-30
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 130 5e-30
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 130 5e-30
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 130 5e-30
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 130 5e-30
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 130 5e-30
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 130 5e-30
AL596132-4|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL596132-3|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL445532-2|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL445532-1|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL390777-4|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL390777-3|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein. 130 5e-30
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 130 5e-30
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 130 5e-30
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 130 5e-30
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 130 7e-30
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 130 7e-30
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 130 7e-30
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 130 7e-30
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 129 1e-29
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 129 1e-29
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 129 1e-29
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 129 1e-29
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 129 1e-29
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 129 1e-29
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 129 1e-29
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 129 1e-29
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 129 1e-29
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 129 1e-29
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 129 1e-29
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 129 1e-29
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 129 1e-29
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 129 1e-29
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 129 1e-29
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 129 1e-29
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 129 1e-29
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 129 1e-29
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 129 1e-29
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 129 1e-29
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 129 2e-29
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 129 2e-29
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 129 2e-29
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 129 2e-29
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 128 2e-29
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 128 2e-29
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 128 2e-29
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 128 2e-29
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 128 2e-29
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 128 2e-29
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 128 2e-29
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 128 2e-29
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 128 2e-29
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 128 2e-29
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 128 2e-29
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 128 2e-29
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 128 2e-29
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 128 2e-29
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 128 2e-29
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 128 2e-29
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 128 2e-29
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 128 2e-29
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 128 3e-29
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 128 3e-29
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 128 3e-29
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 128 4e-29
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 128 4e-29
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 128 4e-29
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 128 4e-29
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 128 4e-29
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 128 4e-29
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 128 4e-29
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 128 4e-29
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 128 4e-29
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 128 4e-29
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 128 4e-29
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 128 4e-29
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 128 4e-29
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 128 4e-29
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 128 4e-29
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 128 4e-29
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 128 4e-29
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 128 4e-29
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 128 4e-29
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 127 5e-29
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 127 5e-29
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 127 5e-29
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 127 5e-29
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 127 5e-29
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 127 5e-29
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 127 5e-29
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 127 5e-29
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 127 7e-29
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 127 7e-29
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 126 1e-28
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 126 1e-28
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 126 1e-28
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 126 1e-28
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 126 1e-28
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 126 1e-28
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 126 1e-28
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 126 1e-28
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 126 1e-28
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 126 1e-28
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 126 1e-28
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 126 1e-28
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 126 1e-28
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 126 1e-28
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 126 1e-28
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 126 1e-28
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 126 1e-28
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 126 2e-28
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 126 2e-28
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 126 2e-28
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 126 2e-28
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 126 2e-28
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 126 2e-28
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 126 2e-28
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 126 2e-28
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 125 2e-28
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 125 2e-28
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 125 2e-28
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 125 3e-28
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 125 3e-28
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 125 3e-28
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 125 3e-28
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 125 3e-28
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 125 3e-28
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 125 3e-28
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 125 3e-28
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 125 3e-28
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 125 3e-28
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 125 3e-28
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 125 3e-28
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 125 3e-28
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 125 3e-28
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 125 3e-28
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 125 3e-28
AL132671-5|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 125 3e-28
AL132671-4|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 125 3e-28
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 125 3e-28
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 125 3e-28
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 125 3e-28
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 124 4e-28
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 124 4e-28
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 124 4e-28
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 124 4e-28
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 124 4e-28
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 124 4e-28
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 124 4e-28
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 124 4e-28
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 124 5e-28
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 124 5e-28
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 124 5e-28
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 124 5e-28
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 124 5e-28
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 124 5e-28
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 124 5e-28
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 124 5e-28
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 124 5e-28
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 124 5e-28
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 124 5e-28
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 124 5e-28
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 124 5e-28
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 124 6e-28
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 124 6e-28
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 124 6e-28
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 124 6e-28
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 124 6e-28
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 124 6e-28
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 124 6e-28
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 124 6e-28
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 124 6e-28
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 124 6e-28
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 124 6e-28
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 124 6e-28
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 124 6e-28
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 123 8e-28
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 123 8e-28
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 123 1e-27
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 123 1e-27
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 123 1e-27
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 122 1e-27
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 122 1e-27
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 122 1e-27
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 122 1e-27
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 122 2e-27
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 122 2e-27
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 122 2e-27
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 122 2e-27
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 122 2e-27
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 122 3e-27
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 121 3e-27
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 121 3e-27
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 121 3e-27
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 121 3e-27
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 121 3e-27
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 121 3e-27
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 121 4e-27
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 121 4e-27
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 120 6e-27
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 120 6e-27
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 120 6e-27
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 120 6e-27
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 120 6e-27
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 120 6e-27
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 120 6e-27
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 120 6e-27
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 120 6e-27
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 120 6e-27
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 120 6e-27
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 120 6e-27
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 120 6e-27
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 120 6e-27
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 120 6e-27
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 120 6e-27
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 120 6e-27
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 120 6e-27
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 120 6e-27
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 120 6e-27
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 120 6e-27
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 120 6e-27
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 120 6e-27
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 120 6e-27
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 120 6e-27
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 120 6e-27
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 120 6e-27
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 120 6e-27
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 120 6e-27
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 120 6e-27
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 120 6e-27
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 120 6e-27
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 120 6e-27
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 120 6e-27
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 120 6e-27
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 120 6e-27
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 120 6e-27
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 120 6e-27
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 120 6e-27
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 120 6e-27
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 120 6e-27
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 120 6e-27
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 120 6e-27
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 120 6e-27
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 120 6e-27
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 120 6e-27
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 120 6e-27
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 120 6e-27
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 120 6e-27
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 120 6e-27
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 120 6e-27
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 120 6e-27
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 120 6e-27
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 120 8e-27
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 120 1e-26
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 120 1e-26
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 120 1e-26
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 120 1e-26
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 120 1e-26
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 120 1e-26
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 120 1e-26
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 119 1e-26
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 119 1e-26
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 119 1e-26
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 119 1e-26
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 119 2e-26
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 119 2e-26
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 119 2e-26
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 119 2e-26
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 119 2e-26
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 119 2e-26
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 118 2e-26
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 118 2e-26
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 118 3e-26
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 118 4e-26
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 118 4e-26
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 118 4e-26
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 118 4e-26
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 118 4e-26
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 118 4e-26
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 118 4e-26
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 118 4e-26
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 117 5e-26
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 117 5e-26
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 117 5e-26
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 117 5e-26
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 117 5e-26
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 117 5e-26
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 117 5e-26
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 117 7e-26
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 117 7e-26
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 117 7e-26
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 117 7e-26
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 117 7e-26
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 116 1e-25
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 116 1e-25
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 116 1e-25
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 116 1e-25
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 116 1e-25
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 116 1e-25
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 116 1e-25
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 116 1e-25
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 116 1e-25
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 116 1e-25
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 116 1e-25
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 116 1e-25
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 116 1e-25
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 116 1e-25
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 115 3e-25
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 115 3e-25
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 115 3e-25
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 115 3e-25
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 115 3e-25
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 115 3e-25
AB209338-1|BAD92575.1| 400|Homo sapiens Hypothetical protein FL... 114 4e-25
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 114 5e-25
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 114 5e-25
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 114 5e-25
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 114 5e-25
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 114 5e-25
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 114 5e-25
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 113 1e-24
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 112 2e-24
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 111 3e-24
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 111 5e-24
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 111 5e-24
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 110 6e-24
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 110 6e-24
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 110 8e-24
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 110 8e-24
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 110 8e-24
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 110 8e-24
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 110 8e-24
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 110 8e-24
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 110 8e-24
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 110 8e-24
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 109 1e-23
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 108 3e-23
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 107 4e-23
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 107 4e-23
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 107 4e-23
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 107 4e-23
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 107 4e-23
AC004416-1|AAF66137.2| 583|Homo sapiens unknown protein. 107 4e-23
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 107 6e-23
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 107 6e-23
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 107 6e-23
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 107 6e-23
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 107 6e-23
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 107 6e-23
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 107 6e-23
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 107 6e-23
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 107 6e-23
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 107 6e-23
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 107 6e-23
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 107 6e-23
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 107 6e-23
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 107 8e-23
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 107 8e-23
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 107 8e-23
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 107 8e-23
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 107 8e-23
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 107 8e-23
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 107 8e-23
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 106 1e-22
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 106 1e-22
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 106 1e-22
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 106 1e-22
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 106 1e-22
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 106 1e-22
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 106 1e-22
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 106 1e-22
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 106 1e-22
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 106 1e-22
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 106 1e-22
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 106 1e-22
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 106 1e-22
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 106 1e-22
AB275889-1|BAF73612.1| 1310|Homo sapiens EML4-ALK variant 2 prot... 106 1e-22
AB274722-1|BAF73611.1| 1059|Homo sapiens EML4-ALK variant 1 prot... 106 1e-22
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 106 1e-22
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 105 2e-22
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 105 2e-22
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 105 2e-22
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 105 2e-22
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 105 2e-22
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 105 2e-22
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 105 2e-22
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 105 2e-22
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 105 2e-22
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 105 2e-22
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 105 2e-22
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 105 2e-22
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 105 2e-22
AL662870-7|CAI18441.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
AL662870-6|CAI18442.1| 913|Homo sapiens discoidin domain recept... 105 2e-22
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 105 2e-22
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 105 2e-22
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 105 2e-22
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 105 2e-22
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 105 2e-22
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 105 2e-22
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 104 4e-22
BC008884-1|AAH08884.1| 352|Homo sapiens TNK2 protein protein. 103 7e-22
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 102 2e-21
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 102 2e-21
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 101 4e-21
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 101 4e-21
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 101 4e-21
AL513328-2|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 101 4e-21
AL513328-1|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 101 4e-21
AL157881-3|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 101 4e-21
AL157881-2|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 101 4e-21
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 101 4e-21
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 101 5e-21
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 101 5e-21
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 101 5e-21
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 101 5e-21
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 101 5e-21
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 101 5e-21
>BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein.
Length = 1129
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 850 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 904
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 905 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 964
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 965 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1024
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1025 ES-KFSVASDVWSFGVVLYELFT 1046
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/226 (27%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 546 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 601
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 602 SHKHLVLNYGVCVC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 660
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 661 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 712
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 713 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 758
>AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein.
Length = 1132
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 853 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 907
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 908 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 967
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 968 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1027
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1028 ES-KFSVASDVWSFGVVLYELFT 1049
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/226 (27%), Positives = 109/226 (48%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 549 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 604
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G + G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 605 SHKHLVLNYGVCFC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 663
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 664 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 715
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 716 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 761
>AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a protein
tyrosine kinase) protein.
Length = 1132
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 853 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 907
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 908 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 967
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 968 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1027
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1028 ES-KFSVASDVWSFGVVLYELFT 1049
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/226 (27%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 549 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 604
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 605 SHKHLVLNYGVCVC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 663
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 664 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 715
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 716 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 761
>AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein.
Length = 1132
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 853 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 907
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 908 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 967
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 968 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1027
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1028 ES-KFSVASDVWSFGVVLYELFT 1049
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/226 (27%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 549 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 604
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 605 SHKHLVLNYGVCVC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 663
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 664 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 715
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 716 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 761
>AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyrosine
kinase protein.
Length = 1132
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 853 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 907
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 908 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 967
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 968 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1027
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1028 ES-KFSVASDVWSFGVVLYELFT 1049
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/226 (27%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 549 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 604
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 605 SHKHLVLNYGVCVC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 663
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 664 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 715
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 716 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 761
>AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein.
Length = 1132
Score = 163 bits (395), Expect = 1e-39
Identities = 88/203 (43%), Positives = 124/203 (61%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+++G GN+G V + Q++ + VA+KKL E DF+ E+EI+KSLQH
Sbjct: 853 QQLGKGNFGSVEMCRYD-PLQDNTGEVVAVKKLQHSTEEH----LRDFEREIEILKSLQH 907
Query: 273 INIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G L ++MEYL GSL YL+ E++ LL+Y I GM+++
Sbjct: 908 DNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYL 967
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
K +HRDLATRNILV N+ VKI DFGL +++P+++ Y++K PI WYAPES
Sbjct: 968 GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLT 1027
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
E FS SDVWS+GV +E+FT
Sbjct: 1028 ES-KFSVASDVWSFGVVLYELFT 1049
Score = 81.8 bits (193), Expect = 3e-15
Identities = 63/226 (27%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER--DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
+ +G G + +FKG D + H EV +K L + + RN + E F +M L
Sbjct: 549 ESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDK--AHRNYS--ESFFEAASMMSKL 604
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H ++V G G E ++V E+++ GSL+ YLK + I L+ K +A M
Sbjct: 605 SHKHLVLNYGVCVC-GDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHF 663
Query: 447 VSAKNVVHRDLATRNILVV--------NKYHVKISDFGLA-RIIPKEENTYRLKTERLLP 599
+ ++H ++ +NIL++ N +K+SD G++ ++PK+ + ER
Sbjct: 664 LEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKD-----ILQER--- 715
Query: 600 INWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
I W PE P + + +D WS+G T WEI + + + D +R
Sbjct: 716 IPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQR 761
>M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase
protein.
Length = 1142
Score = 145 bits (352), Expect = 2e-34
Identities = 77/203 (37%), Positives = 117/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+ +G G++G V D +++ ++VA+K L E G D K E+EI+++L H
Sbjct: 868 RDLGEGHFGKV--ELCRYDPEDNTGEQVAVKSLK---PESGGNHIADLKKEIEILRNLYH 922
Query: 273 INIVEILGYAWDQGPE-VLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G + ++ME+L GSL YL K+ + LKY I GMD++
Sbjct: 923 ENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL 982
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
++ VHRDLA RN+LV +++ VKI DFGL + I ++ Y +K +R P+ WYAPE +
Sbjct: 983 GSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLM 1042
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
+ F SDVWS+GVT E+ T
Sbjct: 1043 QS-KFYIASDVWSFGVTLHELLT 1064
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = +3
Query: 99 IGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
+G G H++ G M+ + E +E IK + + + + F +M+ + H
Sbjct: 577 LGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHK 636
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
+IV + G + E ++V E++E G L+ ++ + + L K K +A+ + ++
Sbjct: 637 HIVYLYGVCV-RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLED 695
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
K++VH ++ T+N+L+ + + P T + E + I W APE +
Sbjct: 696 KDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDS 755
Query: 636 WHFSTKSDVWSYGVTAWEI 692
+ S +D WS+G T WEI
Sbjct: 756 KNLSVAADKWSFGTTLWEI 774
>Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase
protein.
Length = 612
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 346 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 400
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 401 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 457
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 458 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 517
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 518 PE-CINYYKFSSKSDVWSFGVLMWEAFS 544
>X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase
protein.
Length = 630
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 364 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 418
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 419 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 475
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 476 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 535
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 536 PE-CINYYKFSSKSDVWSFGVLMWEAFS 562
>L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase
protein.
Length = 635
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 369 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 423
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 424 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 480
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 541 PE-CINYYKFSSKSDVWSFGVLMWEAFS 567
>BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein.
Length = 612
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 346 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 400
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 401 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 457
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 458 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 517
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 518 PE-CINYYKFSSKSDVWSFGVLMWEAFS 544
>BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 369 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 423
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 424 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 480
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 541 PE-CINYYKFSSKSDVWSFGVLMWEAFS 567
>BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 369 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 423
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 424 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 480
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 541 PE-CINYYKFSSKSDVWSFGVLMWEAFS 567
>AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase
protein.
Length = 612
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 346 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 400
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 401 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 457
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 458 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 517
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 518 PE-CINYYKFSSKSDVWSFGVLMWEAFS 544
>AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 144 bits (349), Expect = 4e-34
Identities = 78/208 (37%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
Frame = +3
Query: 78 LVTLT-KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEI 254
L+TL K++GSGN+G V KG+ + + K VA+K L +A++ L ++ E +
Sbjct: 369 LLTLEDKELGSGNFGTVKKGYYQ---MKKVVKTVAVKILKNEANDP--ALKDELLAEANV 423
Query: 255 MKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIAT 434
M+ L + IV ++G + ++VME E G LN YL+ Q ++ ++++ ++
Sbjct: 424 MQQLDNPYIVRMIGIC--EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSM 480
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ N VHRDLA RN+L+V +++ KISDFGL++ + +EN Y+ +T P+ WYA
Sbjct: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE + + FS+KSDVWS+GV WE F+
Sbjct: 541 PE-CINYYKFSSKSDVWSFGVLMWEAFS 567
>U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosine
kinase protein.
Length = 1124
Score = 142 bits (345), Expect = 1e-33
Identities = 81/204 (39%), Positives = 125/204 (61%), Gaps = 3/204 (1%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKE--VAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
++G GN+G V + R + +H VA+K+L ++ DF+ E++I+K+L
Sbjct: 827 QLGKGNFGSVE---LCRYDPLAHNTGALVAVKQLQHSGPDQQ----RDFQREIQILKALH 879
Query: 270 HINIVEILGYAWDQG-PEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
IV+ G ++ G PE+ +VMEYL G L +L+ +L S LL Y I GM++
Sbjct: 880 SDFIVKYRGVSYGPGRPELRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEY 939
Query: 447 VSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESA 626
+ ++ VHRDLA RNILV ++ HVKI+DFGLA+++P +++ Y ++ PI WYAPES
Sbjct: 940 LGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESL 999
Query: 627 VEPWHFSTKSDVWSYGVTAWEIFT 698
+ FS +SDVWS+GV +E+FT
Sbjct: 1000 SDN-IFSRQSDVWSFGVVLYELFT 1022
Score = 70.5 bits (165), Expect = 8e-12
Identities = 51/219 (23%), Positives = 106/219 (48%), Gaps = 7/219 (3%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
+ +G G++ +++G E + E+ + EV +K + A +N E F +M +
Sbjct: 525 ENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVM--DAKHKN--CMESFLEAASLMSQVS 580
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++V + G + +V E++ G+++ YL+ +G + S L+ K +A ++++
Sbjct: 581 YRHLVLLHGVC--MAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYL 638
Query: 450 SAKNVVHRDLATRNILVVNKY------HVKISDFGLARIIPKEENTYRLKTERLLPINWY 611
K + H +++ R +L+ + +K+SD G++ + E + T+R I W
Sbjct: 639 EDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE----MLTDR---IPWV 691
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
APE E S ++D W +G T WE+F+ + D
Sbjct: 692 APECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALD 730
>BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a protein
tyrosine kinase) protein.
Length = 1154
Score = 142 bits (345), Expect = 1e-33
Identities = 76/203 (37%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+ +G G++G V + + + ++VA+K L E G D K E+EI+++L H
Sbjct: 879 RDLGEGHFGKVELCRYDPEGDNTG-EQVAVKSLK---PESGGNHIADLKKEIEILRNLYH 934
Query: 273 INIVEILGYAWDQGPE-VLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G + ++ME+L GSL YL K+ + LKY I GMD++
Sbjct: 935 ENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL 994
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
++ VHRDLA RN+LV +++ VKI DFGL + I ++ Y +K +R P+ WYAPE +
Sbjct: 995 GSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLM 1054
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
+ F SDVWS+GVT E+ T
Sbjct: 1055 QS-KFYIASDVWSFGVTLHELLT 1076
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = +3
Query: 99 IGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
+G G H++ G M+ + E +E IK + + + + F +M+ + H
Sbjct: 589 LGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHK 648
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
+IV + G + E ++V E++E G L+ ++ + + L K K +A+ + ++
Sbjct: 649 HIVYLYGVCV-RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLED 707
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
K++VH ++ T+N+L+ + + P T + E + I W APE +
Sbjct: 708 KDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDS 767
Query: 636 WHFSTKSDVWSYGVTAWEI 692
+ S +D WS+G T WEI
Sbjct: 768 KNLSVAADKWSFGTTLWEI 786
>AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant
protein.
Length = 1154
Score = 142 bits (345), Expect = 1e-33
Identities = 76/203 (37%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
+ +G G++G V + + + ++VA+K L E G D K E+EI+++L H
Sbjct: 879 RDLGEGHFGKVELCRYDPEGDNTG-EQVAVKSLK---PESGGNHIADLKKEIEILRNLYH 934
Query: 273 INIVEILGYAWDQGPE-VLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
NIV+ G + G + ++ME+L GSL YL K+ + LKY I GMD++
Sbjct: 935 ENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL 994
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
++ VHRDLA RN+LV +++ VKI DFGL + I ++ Y +K +R P+ WYAPE +
Sbjct: 995 GSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLM 1054
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
+ F SDVWS+GVT E+ T
Sbjct: 1055 QS-KFYIASDVWSFGVTLHELLT 1076
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = +3
Query: 99 IGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
+G G H++ G M+ + E +E IK + + + + F +M+ + H
Sbjct: 589 LGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHK 648
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
+IV + G + E ++V E++E G L+ ++ + + L K K +A+ + ++
Sbjct: 649 HIVYLYGVCV-RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLED 707
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
K++VH ++ T+N+L+ + + P T + E + I W APE +
Sbjct: 708 KDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDS 767
Query: 636 WHFSTKSDVWSYGVTAWEI 692
+ S +D WS+G T WEI
Sbjct: 768 KNLSVAADKWSFGTTLWEI 786
>U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein.
Length = 1124
Score = 141 bits (342), Expect = 3e-33
Identities = 79/202 (39%), Positives = 122/202 (60%), Gaps = 1/202 (0%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V + + VA+K+L ++ DF+ E++I+K+L
Sbjct: 827 QLGKGNFGSVELCRYDPLGDNTGAL-VAVKQLQHSGPDQQ----RDFQREIQILKALHSD 881
Query: 276 NIVEILGYAWDQG-PEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVS 452
IV+ G ++ G PE+ +VMEYL G L +L+ +L S LL Y I GM+++
Sbjct: 882 FIVKYRGVSYGPGEPELRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLG 941
Query: 453 AKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVE 632
++ VHRDLA RNILV ++ HVKI+DFGLA+++P +++ Y ++ PI WYAPES +
Sbjct: 942 SRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSD 1001
Query: 633 PWHFSTKSDVWSYGVTAWEIFT 698
FS +SDVWS+GV +E+FT
Sbjct: 1002 N-IFSRQSDVWSFGVVLYELFT 1022
Score = 70.5 bits (165), Expect = 8e-12
Identities = 51/219 (23%), Positives = 106/219 (48%), Gaps = 7/219 (3%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
+ +G G++ +++G E + E+ + EV +K + A +N E F +M +
Sbjct: 525 ENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVM--DAKHKN--CMESFLEAASLMSQVS 580
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++V + G + +V E++ G+++ YL+ +G + S L+ K +A ++++
Sbjct: 581 YRHLVLLHGVC--MAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYL 638
Query: 450 SAKNVVHRDLATRNILVVNKY------HVKISDFGLARIIPKEENTYRLKTERLLPINWY 611
K + H +++ R +L+ + +K+SD G++ + E + T+R I W
Sbjct: 639 EDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE----MLTDR---IPWV 691
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
APE E S ++D W +G T WE+F+ + D
Sbjct: 692 APECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALD 730
>U31601-1|AAC50226.1| 1094|Homo sapiens JAK3B protein.
Length = 1094
Score = 138 bits (333), Expect = 4e-32
Identities = 78/202 (38%), Positives = 121/202 (59%), Gaps = 1/202 (0%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V + + VA+K+L ++ DF+ E++I+K+L
Sbjct: 827 QLGKGNFGSVELCRYDPLGDNTGAL-VAVKQLQHSGPDQQ----RDFQREIQILKALHSD 881
Query: 276 NIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVS 452
IV+ G ++ G + L +VMEYL G L +L+ +L S LL Y I GM+++
Sbjct: 882 FIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLG 941
Query: 453 AKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVE 632
++ VHRDLA RNILV ++ HVKI+DFGLA+++P +++ Y ++ PI WYAPES +
Sbjct: 942 SRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSD 1001
Query: 633 PWHFSTKSDVWSYGVTAWEIFT 698
FS +SDVWS+GV +E+FT
Sbjct: 1002 N-IFSRQSDVWSFGVVLYELFT 1022
Score = 70.5 bits (165), Expect = 8e-12
Identities = 51/219 (23%), Positives = 106/219 (48%), Gaps = 7/219 (3%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
+ +G G++ +++G E + E+ + EV +K + A +N E F +M +
Sbjct: 525 ENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVM--DAKHKN--CMESFLEAASLMSQVS 580
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++V + G + +V E++ G+++ YL+ +G + S L+ K +A ++++
Sbjct: 581 YRHLVLLHGVC--MAGDSTMVQEFVHLGAIDIYLRKRGHLVPASWKLQVVKQLAYALNYL 638
Query: 450 SAKNVVHRDLATRNILVVNKY------HVKISDFGLARIIPKEENTYRLKTERLLPINWY 611
K + H +++ R +L+ + +K+SD G++ + E + T+R I W
Sbjct: 639 EDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE----MLTDR---IPWV 691
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
APE E S ++D W +G T WE+F+ + D
Sbjct: 692 APECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALD 730
>AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a protein
tyrosine kinase, leukocyte) protein.
Length = 1124
Score = 138 bits (333), Expect = 4e-32
Identities = 78/202 (38%), Positives = 121/202 (59%), Gaps = 1/202 (0%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V + + VA+K+L ++ DF+ E++I+K+L
Sbjct: 827 QLGKGNFGSVELCRYDPLGDNTGAL-VAVKQLQHSGPDQQ----RDFQREIQILKALHSD 881
Query: 276 NIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVS 452
IV+ G ++ G + L +VMEYL G L +L+ +L S LL Y I GM+++
Sbjct: 882 FIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLG 941
Query: 453 AKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVE 632
++ VHRDLA RNILV ++ HVKI+DFGLA+++P +++ Y ++ PI WYAPES +
Sbjct: 942 SRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSD 1001
Query: 633 PWHFSTKSDVWSYGVTAWEIFT 698
FS +SDVWS+GV +E+FT
Sbjct: 1002 N-IFSRQSDVWSFGVVLYELFT 1022
Score = 70.5 bits (165), Expect = 8e-12
Identities = 51/219 (23%), Positives = 106/219 (48%), Gaps = 7/219 (3%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
+ +G G++ +++G E + E+ + EV +K + A +N E F +M +
Sbjct: 525 ENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVM--DAKHKN--CMESFLEAASLMSQVS 580
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++V + G + +V E++ G+++ YL+ +G + S L+ K +A ++++
Sbjct: 581 YRHLVLLHGVC--MAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYL 638
Query: 450 SAKNVVHRDLATRNILVVNKY------HVKISDFGLARIIPKEENTYRLKTERLLPINWY 611
K + H +++ R +L+ + +K+SD G++ + E + T+R I W
Sbjct: 639 EDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE----MLTDR---IPWV 691
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
APE E S ++D W +G T WE+F+ + D
Sbjct: 692 APECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALD 730
>AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein.
Length = 1124
Score = 138 bits (333), Expect = 4e-32
Identities = 78/202 (38%), Positives = 121/202 (59%), Gaps = 1/202 (0%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V + + VA+K+L ++ DF+ E++I+K+L
Sbjct: 827 QLGKGNFGSVELCRYDPLGDNTGAL-VAVKQLQHSGPDQQ----RDFQREIQILKALHSD 881
Query: 276 NIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVS 452
IV+ G ++ G + L +VMEYL G L +L+ +L S LL Y I GM+++
Sbjct: 882 FIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLG 941
Query: 453 AKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVE 632
++ VHRDLA RNILV ++ HVKI+DFGLA+++P +++ Y ++ PI WYAPES +
Sbjct: 942 SRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSD 1001
Query: 633 PWHFSTKSDVWSYGVTAWEIFT 698
FS +SDVWS+GV +E+FT
Sbjct: 1002 N-IFSRQSDVWSFGVVLYELFT 1022
Score = 70.5 bits (165), Expect = 8e-12
Identities = 51/219 (23%), Positives = 106/219 (48%), Gaps = 7/219 (3%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
+ +G G++ +++G E + E+ + EV +K + A +N E F +M +
Sbjct: 525 ENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVM--DAKHKN--CMESFLEAASLMSQVS 580
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++V + G + +V E++ G+++ YL+ +G + S L+ K +A ++++
Sbjct: 581 YRHLVLLHGVC--MAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYL 638
Query: 450 SAKNVVHRDLATRNILVVNKY------HVKISDFGLARIIPKEENTYRLKTERLLPINWY 611
K + H +++ R +L+ + +K+SD G++ + E + T+R I W
Sbjct: 639 EDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE----MLTDR---IPWV 691
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
APE E S ++D W +G T WE+F+ + D
Sbjct: 692 APECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALD 730
>BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR)
associated protein kinase 70kDa protein.
Length = 619
Score = 136 bits (329), Expect = 1e-31
Identities = 74/209 (35%), Positives = 125/209 (59%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V +G ++ +VAIK L +Q +E+ T E+ E +IM L +
Sbjct: 343 ELGCGNFGSVRQGVYRMRKKQI---DVAIKVL-KQGTEKADT--EEMMREAQIMHQLDNP 396
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
IV ++G Q +++VME G L+ +L + E++ +S++ + ++ GM ++
Sbjct: 397 YIVRLIGVC--QAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEE 454
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
KN VHRDLA RN+L+VN+++ KISDFGL++ + +++ Y ++ P+ WYAPE +
Sbjct: 455 KNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPE-CINF 513
Query: 636 WHFSTKSDVWSYGVTAWEIFTRARQEVPK 722
FS++SDVWSYGVT WE + ++ K
Sbjct: 514 RKFSSRSDVWSYGVTMWEALSYGQKPYKK 542
>BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein.
Length = 493
Score = 136 bits (329), Expect = 1e-31
Identities = 74/209 (35%), Positives = 125/209 (59%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V +G ++ +VAIK L +Q +E+ T E+ E +IM L +
Sbjct: 217 ELGCGNFGSVRQGVYRMRKKQI---DVAIKVL-KQGTEKADT--EEMMREAQIMHQLDNP 270
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
IV ++G Q +++VME G L+ +L + E++ +S++ + ++ GM ++
Sbjct: 271 YIVRLIGVC--QAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEE 328
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
KN VHRDLA RN+L+VN+++ KISDFGL++ + +++ Y ++ P+ WYAPE +
Sbjct: 329 KNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPE-CINF 387
Query: 636 WHFSTKSDVWSYGVTAWEIFTRARQEVPK 722
FS++SDVWSYGVT WE + ++ K
Sbjct: 388 RKFSSRSDVWSYGVTMWEALSYGQKPYKK 416
>AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein.
Length = 493
Score = 136 bits (329), Expect = 1e-31
Identities = 74/209 (35%), Positives = 125/209 (59%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V +G ++ +VAIK L +Q +E+ T E+ E +IM L +
Sbjct: 217 ELGCGNFGSVRQGVYRMRKKQI---DVAIKVL-KQGTEKADT--EEMMREAQIMHQLDNP 270
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
IV ++G Q +++VME G L+ +L + E++ +S++ + ++ GM ++
Sbjct: 271 YIVRLIGVC--QAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEE 328
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
KN VHRDLA RN+L+VN+++ KISDFGL++ + +++ Y ++ P+ WYAPE +
Sbjct: 329 KNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPE-CINF 387
Query: 636 WHFSTKSDVWSYGVTAWEIFTRARQEVPK 722
FS++SDVWSYGVT WE + ++ K
Sbjct: 388 RKFSSRSDVWSYGVTMWEALSYGQKPYKK 416
>AB219242-1|BAE02826.1| 1141|Homo sapiens janus kinase 1 protein.
Length = 1141
Score = 136 bits (329), Expect = 1e-31
Identities = 78/204 (38%), Positives = 115/204 (56%), Gaps = 2/204 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMER-DNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K+I GH K + R D +++ ++VA+K L E G D K E+EI+++L
Sbjct: 864 KRIRDLEEGHFGKVELCRYDPEDNTGEQVAVKSLK---PESGGNHIADLKKEIEILRNLY 920
Query: 270 HINIVEILGYAWDQGPE-VLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDH 446
H NIV+ G + G + ++ME+L GSL YL K+ + LKY I GMD+
Sbjct: 921 HENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDY 980
Query: 447 VSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESA 626
+ ++ VHRDLA RN+LV +++ VKI DFGL + I ++ Y +K +R P YAPE
Sbjct: 981 LGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPKFGYAPECL 1040
Query: 627 VEPWHFSTKSDVWSYGVTAWEIFT 698
++ F SDVWS+GVT E+ T
Sbjct: 1041 MQS-KFYIASDVWSFGVTLHELLT 1063
Score = 70.1 bits (164), Expect = 1e-11
Identities = 46/199 (23%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = +3
Query: 99 IGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
+G G H++ G M+ + E +E IK + + + + F +++ + H
Sbjct: 577 LGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMIRQVSHK 636
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
+IV + G + E ++V E++E G L+ ++ + + L K K +A+ + ++
Sbjct: 637 HIVYLYGVCV-RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLED 695
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
K++VH ++ T+N+L+ + + P T + E + I W APE +
Sbjct: 696 KDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDS 755
Query: 636 WHFSTKSDVWSYGVTAWEI 692
+ +D WS+G T WEI
Sbjct: 756 KNLCVAADKWSFGTTLWEI 774
>AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase
protein.
Length = 312
Score = 136 bits (329), Expect = 1e-31
Identities = 74/209 (35%), Positives = 125/209 (59%)
Frame = +3
Query: 96 KIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHI 275
++G GN+G V +G ++ +VAIK L +Q +E+ T E+ E +IM L +
Sbjct: 36 ELGCGNFGSVRQGVYRMRKKQI---DVAIKVL-KQGTEKADT--EEMMREAQIMHQLDNP 89
Query: 276 NIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSA 455
IV ++G Q +++VME G L+ +L + E++ +S++ + ++ GM ++
Sbjct: 90 YIVRLIGVC--QAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEE 147
Query: 456 KNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEP 635
KN VHRDLA RN+L+VN+++ KISDFGL++ + +++ Y ++ P+ WYAPE +
Sbjct: 148 KNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPE-CINF 206
Query: 636 WHFSTKSDVWSYGVTAWEIFTRARQEVPK 722
FS++SDVWSYGVT WE + ++ K
Sbjct: 207 RKFSSRSDVWSYGVTMWEALSYGQKPYKK 235
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 135 bits (327), Expect = 2e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 612
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 613 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 671
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLK-TERLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 672 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTAP 729
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 730 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 771
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes variant
4 protein.
Length = 752
Score = 135 bits (327), Expect = 2e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 491 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 542
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 543 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 601
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLK-TERLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 602 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTAP 659
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 660 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 701
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes variant
3 protein.
Length = 764
Score = 135 bits (327), Expect = 2e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 503 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 554
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 555 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 613
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLK-TERLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 614 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTAP 671
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 672 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 713
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes variant
1 protein.
Length = 694
Score = 135 bits (327), Expect = 2e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 433 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 484
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 485 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 543
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLK-TERLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 544 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTAP 601
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 602 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 643
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 134 bits (325), Expect = 3e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 612
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 613 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 671
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTE-RLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 672 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAP 729
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 730 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 771
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 134 bits (325), Expect = 3e-31
Identities = 79/223 (35%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++IG GN+G VF G + DN VA+K L F E I+K
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPP---DLKAKFLQEARILK 612
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV ++G + P + IVME ++ G +L+ +G +LR+ LL+ D A GM
Sbjct: 613 QYSHPNIVRLIGVCTQKQP-IYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGM 671
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTE-RLLPINWYAP 617
+++ +K +HRDLA RN LV K +KISDFG++R + + Y R +P+ W AP
Sbjct: 672 EYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAP 729
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A+ +S++SDVWS+G+ WE F+ P ++ RE
Sbjct: 730 E-ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE 771
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 133 bits (322), Expect = 8e-31
Identities = 78/219 (35%), Positives = 122/219 (55%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+++++G G++G V++G + ++ VAIK + AS R +F NE +MK
Sbjct: 999 ITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERI---EFLNEASVMK 1055
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG QG L++ME + G L YL+ ++ +S +++
Sbjct: 1056 EFNCHHVVRLLGVV-SQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQ 1114
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++A VHRDLA RN +V + VKI DFG+ R I E + YR + L
Sbjct: 1115 MAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1173
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W +PES ++ F+T SDVWS+GV WEI T A Q
Sbjct: 1174 LPVRWMSPES-LKDGVFTTYSDVWSFGVVLWEIATLAEQ 1211
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 133 bits (322), Expect = 8e-31
Identities = 77/207 (37%), Positives = 118/207 (57%), Gaps = 1/207 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
VT K IG+G +G V+KG ++ + + VAIK L +E+ DF E IM
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKE-VPVAIKTLKAGYTEKQRV---DFLGEAGIMG 668
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P ++I+ EY+E G+L+ +L+ + + + L+ + IA GM
Sbjct: 669 QFSHHNIIRLEGVISKYKP-MMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGM 727
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWYAP 617
+++ N VHRDLA RNILV + K+SDFGL+R++ + E TY + +PI W AP
Sbjct: 728 KYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK-IPIRWTAP 786
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFT 698
E A+ F++ SDVWS+G+ WE+ T
Sbjct: 787 E-AISYRKFTSASDVWSFGIVMWEVMT 812
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 133 bits (322), Expect = 8e-31
Identities = 78/219 (35%), Positives = 122/219 (55%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+++++G G++G V++G + ++ VAIK + AS R +F NE +MK
Sbjct: 999 ITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERI---EFLNEASVMK 1055
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG QG L++ME + G L YL+ ++ +S +++
Sbjct: 1056 EFNCHHVVRLLGVV-SQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQ 1114
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++A VHRDLA RN +V + VKI DFG+ R I E + YR + L
Sbjct: 1115 MAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1173
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W +PES ++ F+T SDVWS+GV WEI T A Q
Sbjct: 1174 LPVRWMSPES-LKDGVFTTYSDVWSFGVVLWEIATLAEQ 1211
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 133 bits (322), Expect = 8e-31
Identities = 78/219 (35%), Positives = 122/219 (55%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+++++G G++G V++G + ++ VAIK + AS R +F NE +MK
Sbjct: 999 ITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERI---EFLNEASVMK 1055
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG QG L++ME + G L YL+ ++ +S +++
Sbjct: 1056 EFNCHHVVRLLGVV-SQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQ 1114
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++A VHRDLA RN +V + VKI DFG+ R I E + YR + L
Sbjct: 1115 MAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1173
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W +PES ++ F+T SDVWS+GV WEI T A Q
Sbjct: 1174 LPVRWMSPES-LKDGVFTTYSDVWSFGVVLWEIATLAEQ 1211
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 133 bits (322), Expect = 8e-31
Identities = 77/207 (37%), Positives = 118/207 (57%), Gaps = 1/207 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
VT K IG+G +G V+KG ++ + + VAIK L +E+ DF E IM
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKE-VPVAIKTLKAGYTEKQRV---DFLGEAGIMG 668
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P ++I+ EY+E G+L+ +L+ + + + L+ + IA GM
Sbjct: 669 QFSHHNIIRLEGVISKYKP-MMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGM 727
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWYAP 617
+++ N VHRDLA RNILV + K+SDFGL+R++ + E TY + +PI W AP
Sbjct: 728 KYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK-IPIRWTAP 786
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFT 698
E A+ F++ SDVWS+G+ WE+ T
Sbjct: 787 E-AISYRKFTSASDVWSFGIVMWEVMT 812
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 133 bits (322), Expect = 8e-31
Identities = 78/219 (35%), Positives = 122/219 (55%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+++++G G++G V++G + ++ VAIK + AS R +F NE +MK
Sbjct: 999 ITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERI---EFLNEASVMK 1055
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG QG L++ME + G L YL+ ++ +S +++
Sbjct: 1056 EFNCHHVVRLLGVV-SQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQ 1114
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++A VHRDLA RN +V + VKI DFG+ R I E + YR + L
Sbjct: 1115 MAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1173
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W +PES ++ F+T SDVWS+GV WEI T A Q
Sbjct: 1174 LPVRWMSPES-LKDGVFTTYSDVWSFGVVLWEIATLAEQ 1211
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 133 bits (322), Expect = 8e-31
Identities = 77/207 (37%), Positives = 118/207 (57%), Gaps = 1/207 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
VT K IG+G +G V+KG ++ + + VAIK L +E+ DF E IM
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKE-VPVAIKTLKAGYTEKQRV---DFLGEAGIMG 668
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P ++I+ EY+E G+L+ +L+ + + + L+ + IA GM
Sbjct: 669 QFSHHNIIRLEGVISKYKP-MMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGM 727
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWYAP 617
+++ N VHRDLA RNILV + K+SDFGL+R++ + E TY + +PI W AP
Sbjct: 728 KYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK-IPIRWTAP 786
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFT 698
E A+ F++ SDVWS+G+ WE+ T
Sbjct: 787 E-AISYRKFTSASDVWSFGIVMWEVMT 812
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 132 bits (318), Expect = 2e-30
Identities = 75/210 (35%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+T ++IGSG +G V G W+ +D +VAIK + A EDF E E+M
Sbjct: 363 LTFVQEIGSGQFGLVHLGYWLNKD-------KVAIKTIREGAMSE-----EDFIEEAEVM 410
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
L H +V++ G +Q P + +V E++E G L+ YL+ Q LL C D+ G
Sbjct: 411 MKLSHPKLVQLYGVCLEQAP-ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ V+HRDLA RN LV +K+SDFG+ R + ++ Y T P+ W +P
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASP 527
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRAR 707
E +S+KSDVWS+GV WE+F+ +
Sbjct: 528 E-VFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 132 bits (318), Expect = 2e-30
Identities = 75/210 (35%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+T ++IGSG +G V G W+ +D +VAIK + A EDF E E+M
Sbjct: 363 LTFVQEIGSGQFGLVHLGYWLNKD-------KVAIKTIREGAMSE-----EDFIEEAEVM 410
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
L H +V++ G +Q P + +V E++E G L+ YL+ Q LL C D+ G
Sbjct: 411 MKLSHPKLVQLYGVCLEQAP-ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ V+HRDLA RN LV +K+SDFG+ R + ++ Y T P+ W +P
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASP 527
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRAR 707
E +S+KSDVWS+GV WE+F+ +
Sbjct: 528 E-VFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 132 bits (318), Expect = 2e-30
Identities = 75/210 (35%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+T ++IGSG +G V G W+ +D +VAIK + A EDF E E+M
Sbjct: 363 LTFVQEIGSGQFGLVHLGYWLNKD-------KVAIKTIREGAMSE-----EDFIEEAEVM 410
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
L H +V++ G +Q P + +V E++E G L+ YL+ Q LL C D+ G
Sbjct: 411 MKLSHPKLVQLYGVCLEQAP-ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ V+HRDLA RN LV +K+SDFG+ R + ++ Y T P+ W +P
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASP 527
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRAR 707
E +S+KSDVWS+GV WE+F+ +
Sbjct: 528 E-VFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 132 bits (318), Expect = 2e-30
Identities = 75/210 (35%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+T ++IGSG +G V G W+ +D +VAIK + A EDF E E+M
Sbjct: 363 LTFVQEIGSGQFGLVHLGYWLNKD-------KVAIKTIREGAMSE-----EDFIEEAEVM 410
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
L H +V++ G +Q P + +V E++E G L+ YL+ Q LL C D+ G
Sbjct: 411 MKLSHPKLVQLYGVCLEQAP-ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ V+HRDLA RN LV +K+SDFG+ R + ++ Y T P+ W +P
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASP 527
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRAR 707
E +S+KSDVWS+GV WE+F+ +
Sbjct: 528 E-VFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 132 bits (318), Expect = 2e-30
Identities = 75/210 (35%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+T ++IGSG +G V G W+ +D +VAIK + A EDF E E+M
Sbjct: 363 LTFVQEIGSGQFGLVHLGYWLNKD-------KVAIKTIREGAMSE-----EDFIEEAEVM 410
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
L H +V++ G +Q P + +V E++E G L+ YL+ Q LL C D+ G
Sbjct: 411 MKLSHPKLVQLYGVCLEQAP-ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ V+HRDLA RN LV +K+SDFG+ R + ++ Y T P+ W +P
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASP 527
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRAR 707
E +S+KSDVWS+GV WE+F+ +
Sbjct: 528 E-VFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 131 bits (316), Expect = 4e-30
Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 E-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 435
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 131 bits (316), Expect = 4e-30
Identities = 75/228 (32%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 1065 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 1120
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 1121 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A GM ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 1238
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 1239 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVVLWELMTRGAPPYP 1285
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 131 bits (316), Expect = 4e-30
Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 E-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 435
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 131 bits (316), Expect = 4e-30
Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 E-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 435
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 131 bits (316), Expect = 4e-30
Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 E-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 435
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 131 bits (316), Expect = 4e-30
Identities = 81/223 (36%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 E-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 435
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 130 bits (315), Expect = 5e-30
Identities = 83/214 (38%), Positives = 124/214 (57%), Gaps = 2/214 (0%)
Frame = +3
Query: 84 TLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
TL +K+GSG +G VF+G W +R +VAIK ++R N + ++E++ MK
Sbjct: 192 TLCRKLGSGYFGEVFEGLWKDR-------VQVAIKVISRD----NLLHQQMLQSEIQAMK 240
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATG 437
L+H +I+ + G V I+ E + +GSL L+ EK L +S LL +A G
Sbjct: 241 KLRHKHILALYAVV-SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEG 299
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ ++N +HRDLA RNILV K+ DFGLAR+I +E+ Y L + +P W AP
Sbjct: 300 MCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLI--KEDVY-LSHDHNIPYKWTAP 356
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E A+ H+STKSDVWS+G+ E+F+R + P
Sbjct: 357 E-ALSRGHYSTKSDVWSFGILLHEMFSRGQVPYP 389
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 130 bits (315), Expect = 5e-30
Identities = 83/214 (38%), Positives = 124/214 (57%), Gaps = 2/214 (0%)
Frame = +3
Query: 84 TLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
TL +K+GSG +G VF+G W +R +VAIK ++R N + ++E++ MK
Sbjct: 192 TLCRKLGSGYFGEVFEGLWKDR-------VQVAIKVISRD----NLLHQQMLQSEIQAMK 240
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATG 437
L+H +I+ + G V I+ E + +GSL L+ EK L +S LL +A G
Sbjct: 241 KLRHKHILALYAVV-SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEG 299
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ ++N +HRDLA RNILV K+ DFGLAR+I +E+ Y L + +P W AP
Sbjct: 300 MCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLI--KEDVY-LSHDHNIPYKWTAP 356
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E A+ H+STKSDVWS+G+ E+F+R + P
Sbjct: 357 E-ALSRGHYSTKSDVWSFGILLHEMFSRGQVPYP 389
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 130 bits (315), Expect = 5e-30
Identities = 75/228 (32%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 198 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 253
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 254 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 311
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A GM ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 312 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 371
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 372 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 418
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 130 bits (315), Expect = 5e-30
Identities = 75/228 (32%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 130 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 185
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 186 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 243
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A GM ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 244 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 303
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 304 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 350
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 130 bits (315), Expect = 5e-30
Identities = 75/228 (32%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 1065 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 1120
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 1121 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A GM ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 1238
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 1239 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 1285
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 130 bits (315), Expect = 5e-30
Identities = 83/214 (38%), Positives = 124/214 (57%), Gaps = 2/214 (0%)
Frame = +3
Query: 84 TLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
TL +K+GSG +G VF+G W +R +VAIK ++R N + ++E++ MK
Sbjct: 192 TLCRKLGSGYFGEVFEGLWKDR-------VQVAIKVISRD----NLLHQQMLQSEIQAMK 240
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATG 437
L+H +I+ + G V I+ E + +GSL L+ EK L +S LL +A G
Sbjct: 241 KLRHKHILALYAVV-SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEG 299
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ ++N +HRDLA RNILV K+ DFGLAR+I +E+ Y L + +P W AP
Sbjct: 300 MCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLI--KEDVY-LSHDHNIPYKWTAP 356
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E A+ H+STKSDVWS+G+ E+F+R + P
Sbjct: 357 E-ALSRGHYSTKSDVWSFGILLHEMFSRGQVPYP 389
>AL596132-4|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 543 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 598
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 599 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 657
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 658 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 717
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 718 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 768
>AL596132-3|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>AL445532-2|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 543 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 598
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 599 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 657
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 658 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 717
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 718 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 768
>AL445532-1|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>AL390777-4|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 543 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 598
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 599 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 657
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 658 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 717
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 718 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 768
>AL390777-3|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein.
Length = 451
Score = 130 bits (315), Expect = 5e-30
Identities = 83/214 (38%), Positives = 124/214 (57%), Gaps = 2/214 (0%)
Frame = +3
Query: 84 TLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
TL +K+GSG +G VF+G W +R +VAIK ++R N + ++E++ MK
Sbjct: 192 TLCRKLGSGYFGEVFEGLWKDR-------VQVAIKVISRD----NLLHQQMLQSEIQAMK 240
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATG 437
L+H +I+ + G V I+ E + +GSL L+ EK L +S LL +A G
Sbjct: 241 KLRHKHILALYAVV-SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEG 299
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M ++ ++N +HRDLA RNILV K+ DFGLAR+I +E+ Y L + +P W AP
Sbjct: 300 MCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLI--KEDVY-LSHDHNIPYKWTAP 356
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E A+ H+STKSDVWS+G+ E+F+R + P
Sbjct: 357 E-ALSRGHYSTKSDVWSFGILLHEMFSRGQVPYP 389
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 543 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 598
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 599 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 657
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 658 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 717
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 718 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 768
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine kinase
receptor type 2 protein.
Length = 822
Score = 130 bits (315), Expect = 5e-30
Identities = 83/233 (35%), Positives = 128/233 (54%), Gaps = 12/233 (5%)
Frame = +3
Query: 48 ESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY 227
++ V K + + L +++G G +G VF E + VA+K L + AS+
Sbjct: 527 DTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDN---AR 582
Query: 228 EDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE------- 386
+DF E E++ +LQH +IV+ G + P +++V EY++ G LN +L+ G
Sbjct: 583 KDFHREAELLTNLQHEHIVKFYGVCVEGDP-LIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 387 -----KLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARII 551
+L S +L + IA GM ++++++ VHRDLATRN LV VKI DFG++R +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 552 PKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ YR+ +LPI W PES + F+T+SDVWS GV WEIFT +Q
Sbjct: 702 -YSTDYYRVGGHTMLPIRWMPPESIMYR-KFTTESDVWSLGVVLWEIFTYGKQ 752
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene precursor
variant protein.
Length = 712
Score = 130 bits (315), Expect = 5e-30
Identities = 75/228 (32%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 387 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 442
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 443 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 500
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A GM ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 501 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 560
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 561 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 607
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 130 bits (314), Expect = 7e-30
Identities = 73/200 (36%), Positives = 117/200 (58%)
Frame = +3
Query: 99 IGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHIN 278
IG G +G V++G + +Q+ K VAIK L + G + +F E IM H +
Sbjct: 345 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSP---GGQWWNFLREATIMGQFSHPH 399
Query: 279 IVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAK 458
I+ + G + P ++I+ E++E G+L+ +L+ + ++L L+ + IA+GM+++S
Sbjct: 400 ILHLEGVVTKRKP-IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 458
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N VHRDLA RNILV K+SDFGL R++ + TY + + +PI W APE A+
Sbjct: 459 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPE-AIAHR 516
Query: 639 HFSTKSDVWSYGVTAWEIFT 698
F+T SDVWS+G+ WE+ +
Sbjct: 517 IFTTASDVWSFGIVMWEVLS 536
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 130 bits (314), Expect = 7e-30
Identities = 73/200 (36%), Positives = 117/200 (58%)
Frame = +3
Query: 99 IGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHIN 278
IG G +G V++G + +Q+ K VAIK L + G + +F E IM H +
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSP---GGQWWNFLREATIMGQFSHPH 684
Query: 279 IVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAK 458
I+ + G + P ++I+ E++E G+L+ +L+ + ++L L+ + IA+GM+++S
Sbjct: 685 ILHLEGVVTKRKP-IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N VHRDLA RNILV K+SDFGL R++ + TY + + +PI W APE A+
Sbjct: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPE-AIAHR 801
Query: 639 HFSTKSDVWSYGVTAWEIFT 698
F+T SDVWS+G+ WE+ +
Sbjct: 802 IFTTASDVWSFGIVMWEVLS 821
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 130 bits (314), Expect = 7e-30
Identities = 73/200 (36%), Positives = 117/200 (58%)
Frame = +3
Query: 99 IGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHIN 278
IG G +G V++G + +Q+ K VAIK L + G + +F E IM H +
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSP---GGQWWNFLREATIMGQFSHPH 684
Query: 279 IVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAK 458
I+ + G + P ++I+ E++E G+L+ +L+ + ++L L+ + IA+GM+++S
Sbjct: 685 ILHLEGVVTKRKP-IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N VHRDLA RNILV K+SDFGL R++ + TY + + +PI W APE A+
Sbjct: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPE-AIAHR 801
Query: 639 HFSTKSDVWSYGVTAWEIFT 698
F+T SDVWS+G+ WE+ +
Sbjct: 802 IFTTASDVWSFGIVMWEVLS 821
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 130 bits (314), Expect = 7e-30
Identities = 73/200 (36%), Positives = 117/200 (58%)
Frame = +3
Query: 99 IGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHIN 278
IG G +G V++G + +Q+ K VAIK L + G + +F E IM H +
Sbjct: 630 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSP---GGQWWNFLREATIMGQFSHPH 684
Query: 279 IVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAK 458
I+ + G + P ++I+ E++E G+L+ +L+ + ++L L+ + IA+GM+++S
Sbjct: 685 ILHLEGVVTKRKP-IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N VHRDLA RNILV K+SDFGL R++ + TY + + +PI W APE A+
Sbjct: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPE-AIAHR 801
Query: 639 HFSTKSDVWSYGVTAWEIFT 698
F+T SDVWS+G+ WE+ +
Sbjct: 802 IFTTASDVWSFGIVMWEVLS 821
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 129 bits (312), Expect = 1e-29
Identities = 83/213 (38%), Positives = 121/213 (56%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K++G+G +G V WM N + +VAIK L + GT+ E F E +IMK
Sbjct: 273 LIKRLGNGQFGEV---WMGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 320
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 321 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 436
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 437 AALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 468
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 242 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 291
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 292 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 350
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 408
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 409 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 129 bits (312), Expect = 1e-29
Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 3/209 (1%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+ L K++GSG +G V++G W ++ VA+K L + + N DF E +IM
Sbjct: 234 IQLLKRLGSGQFGEVWEGLW-------NNTTPVAVKTLKPGSMDPN-----DFLREAQIM 281
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIAT 434
K+L+H ++++ + P + I+ E + GSL YL+ G K+ ++ + +A+
Sbjct: 282 KNLRHPKLIQLYAVCTLEDP-IYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVAS 340
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWY 611
GM ++ ++N +HRDLA RN+LV K++DFGLAR+ + E+ Y + E LP+ W
Sbjct: 341 GMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWT 400
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFT 698
APE A+ FS KSDVWS+G+ +EI T
Sbjct: 401 APE-AIRSNKFSIKSDVWSFGILLYEIIT 428
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 242 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 291
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 292 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 350
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 408
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 409 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 261 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 310
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 311 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 427
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 428 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 129 bits (312), Expect = 1e-29
Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 3/209 (1%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+ L K++GSG +G V++G W ++ VA+K L + + N DF E +IM
Sbjct: 234 IQLLKRLGSGQFGEVWEGLW-------NNTTPVAVKTLKPGSMDPN-----DFLREAQIM 281
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIAT 434
K+L+H ++++ + P + I+ E + GSL YL+ G K+ ++ + +A+
Sbjct: 282 KNLRHPKLIQLYAVCTLEDP-IYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVAS 340
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWY 611
GM ++ ++N +HRDLA RN+LV K++DFGLAR+ + E+ Y + E LP+ W
Sbjct: 341 GMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWT 400
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFT 698
APE A+ FS KSDVWS+G+ +EI T
Sbjct: 401 APE-AIRSNKFSIKSDVWSFGILLYEIIT 428
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 288 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 337
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 338 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 454
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 455 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 493
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 129 bits (312), Expect = 1e-29
Identities = 83/213 (38%), Positives = 121/213 (56%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K++G+G +G V WM N + +VAIK L + GT+ E F E +IMK
Sbjct: 273 LIKRLGNGQFGEV---WMGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 320
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 321 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 436
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 437 AALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 468
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 261 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 310
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 311 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 427
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 428 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 288 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 337
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 338 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 454
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 455 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 493
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 301 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 350
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 351 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 409
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 410 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 467
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 468 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 506
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 261 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 310
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 311 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 427
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 428 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 273 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 322
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 323 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 439
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 440 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 478
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 129 bits (312), Expect = 1e-29
Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 3/209 (1%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+ L K++GSG +G V++G W ++ VA+K L + + N DF E +IM
Sbjct: 234 IQLLKRLGSGQFGEVWEGLW-------NNTTPVAVKTLKPGSMDPN-----DFLREAQIM 281
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIAT 434
K+L+H ++++ + P + I+ E + GSL YL+ G K+ ++ + +A+
Sbjct: 282 KNLRHPKLIQLYAVCTLEDP-IYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVAS 340
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWY 611
GM ++ ++N +HRDLA RN+LV K++DFGLAR+ + E+ Y + E LP+ W
Sbjct: 341 GMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWT 400
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFT 698
APE A+ FS KSDVWS+G+ +EI T
Sbjct: 401 APE-AIRSNKFSIKSDVWSFGILLYEIIT 428
>AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein.
Length = 1187
Score = 129 bits (312), Expect = 1e-29
Identities = 75/211 (35%), Positives = 124/211 (58%), Gaps = 1/211 (0%)
Frame = +3
Query: 69 KTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNEL 248
K YL + + +G G++G V + N + + VA+K L ++ + +K E+
Sbjct: 894 KRYLKKI-RDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRS---GWKQEI 948
Query: 249 EIMKSLQHINIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKD 425
+I+++L H +I++ G DQG + L +VMEY+ GSL YL + ++ LL + +
Sbjct: 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
Query: 426 IATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPIN 605
I GM ++ A++ +HRDLA RN+L+ N VKI DFGLA+ +P+ YR++ + P+
Sbjct: 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
Query: 606 WYAPESAVEPWHFSTKSDVWSYGVTAWEIFT 698
WYAPE ++ + F SDVWS+GVT +E+ T
Sbjct: 1067 WYAPE-CLKEYKFYYASDVWSFGVTLYELLT 1096
Score = 56.8 bits (131), Expect = 1e-07
Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = +3
Query: 234 FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLK 413
F +M + H ++ + G +GPE ++V EY+E G L+ +L+ + + ++ +
Sbjct: 655 FYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+ +A+ + ++ KN+VH ++ RNIL+ + + + P + ER+
Sbjct: 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
Query: 594 LPINWYAPESAVEPWH-FSTKSDVWSYGVTAWEI 692
I W APE + ST D W +G T EI
Sbjct: 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 288 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 337
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 338 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 454
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 455 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 493
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 273 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 322
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 323 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 439
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 440 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 478
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 288 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 337
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 338 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 454
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 455 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 493
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 273 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 322
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 323 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 439
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 440 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 478
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 261 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 310
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 311 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 427
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 428 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 129 bits (312), Expect = 1e-29
Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 3/209 (1%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+ L K++GSG +G V++G W ++ VA+K L + + N DF E +IM
Sbjct: 234 IQLLKRLGSGQFGEVWEGLW-------NNTTPVAVKTLKPGSMDPN-----DFLREAQIM 281
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIAT 434
K+L+H ++++ + P + I+ E + GSL YL+ G K+ ++ + +A+
Sbjct: 282 KNLRHPKLIQLYAVCTLEDP-IYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVAS 340
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWY 611
GM ++ ++N +HRDLA RN+LV K++DFGLAR+ + E+ Y + E LP+ W
Sbjct: 341 GMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWT 400
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFT 698
APE A+ FS KSDVWS+G+ +EI T
Sbjct: 401 APE-AIRSNKFSIKSDVWSFGILLYEIIT 428
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 261 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 310
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 311 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 427
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 428 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 469
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 242 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 291
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 292 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 350
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 408
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 409 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 450
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 288 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 337
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 338 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 454
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 455 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 493
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 129 bits (312), Expect = 1e-29
Identities = 79/220 (35%), Positives = 117/220 (53%), Gaps = 1/220 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V+ G ++ + VA+K L E E+F E +MK
Sbjct: 273 ITMKHKLGGGQYGEVYVGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 322
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P IV EY+ G+L YL+ E++ LL I++
Sbjct: 323 EIKHPNLVQLLGVCTLE-PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 439
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVER 737
ES FS KSDVW++GV WEI T P D+ +
Sbjct: 440 ESLAYN-TFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ 478
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 129 bits (312), Expect = 1e-29
Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 3/209 (1%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+ L K++GSG +G V++G W ++ VA+K L + + N DF E +IM
Sbjct: 234 IQLLKRLGSGQFGEVWEGLW-------NNTTPVAVKTLKPGSMDPN-----DFLREAQIM 281
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIAT 434
K+L+H ++++ + P + I+ E + GSL YL+ G K+ ++ + +A+
Sbjct: 282 KNLRHPKLIQLYAVCTLEDP-IYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVAS 340
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE-ENTYRLKTERLLPINWY 611
GM ++ ++N +HRDLA RN+LV K++DFGLAR+ + E+ Y + E LP+ W
Sbjct: 341 GMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWT 400
Query: 612 APESAVEPWHFSTKSDVWSYGVTAWEIFT 698
APE A+ FS KSDVWS+G+ +EI T
Sbjct: 401 APE-AIRSNKFSIKSDVWSFGILLYEIIT 428
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 129 bits (312), Expect = 1e-29
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 279 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 328
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 329 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 387
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 388 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 445
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
ES FS KSDVW++GV WEI T P D+ + E
Sbjct: 446 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 487
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 129 bits (311), Expect = 2e-29
Identities = 74/208 (35%), Positives = 115/208 (55%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V+KG ++ + VAIK L SE+ DF +E IM
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIY--VAIKTLKAGYSEKQR---RDFLSEASIMG 673
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 674 QFDHPNIIRLEGVVTKSRP-VMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +P+ W A
Sbjct: 733 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SDVWSYG+ WE+ +
Sbjct: 793 PE-AIAYRKFTSASDVWSYGIVMWEVMS 819
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 129 bits (311), Expect = 2e-29
Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E+ + VAIK L + +F +E IM S+
Sbjct: 722 KVLGSGAFGTVYKGIWVPEG--ETVKIPVAIKILNETTGPKANV---EFMDEALIMASMD 776
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
H ++V +LG P + +V + + G L Y+ + + LL +C IA GM ++
Sbjct: 777 HPHLVRLLGVCLS--PTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYL 834
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV + HVKI+DFGLAR++ +E Y + +PI W A E +
Sbjct: 835 EERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGK-MPIKWMALE-CI 892
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
F+ +SDVWSYGVT WE+ T
Sbjct: 893 HYRKFTHQSDVWSYGVTIWELMT 915
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 129 bits (311), Expect = 2e-29
Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E+ + VAIK L + +F +E IM S+
Sbjct: 722 KVLGSGAFGTVYKGIWVPEG--ETVKIPVAIKILNETTGPKANV---EFMDEALIMASMD 776
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
H ++V +LG P + +V + + G L Y+ + + LL +C IA GM ++
Sbjct: 777 HPHLVRLLGVCLS--PTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYL 834
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV + HVKI+DFGLAR++ +E Y + +PI W A E +
Sbjct: 835 EERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGK-MPIKWMALE-CI 892
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
F+ +SDVWSYGVT WE+ T
Sbjct: 893 HYRKFTHQSDVWSYGVTIWELMT 915
>AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 variant protein.
Length = 892
Score = 129 bits (311), Expect = 2e-29
Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E+ + VAIK L + +F +E IM S+
Sbjct: 322 KVLGSGAFGTVYKGIWVPEG--ETVKIPVAIKILNETTGPKANV---EFMDEALIMASMD 376
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
H ++V +LG P + +V + + G L Y+ + + LL +C IA GM ++
Sbjct: 377 HPHLVRLLGVCLS--PTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYL 434
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV + HVKI+DFGLAR++ +E Y + +PI W A E +
Sbjct: 435 EERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGK-MPIKWMALE-CI 492
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
F+ +SDVWSYGVT WE+ T
Sbjct: 493 HYRKFTHQSDVWSYGVTIWELMT 515
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 305 IVLKWELGEGAFGKVFLAESHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 360
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 361 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 419
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 420 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 478
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 479 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 521
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 217 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 272
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 273 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 331
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 332 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 390
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 391 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 433
>X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA for
non-receptor protein tyrosine kinase. ).
Length = 1187
Score = 128 bits (310), Expect = 2e-29
Identities = 75/211 (35%), Positives = 123/211 (58%), Gaps = 1/211 (0%)
Frame = +3
Query: 69 KTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNEL 248
K YL + + +G G++G V + N + + VA+K L ++ + +K E+
Sbjct: 894 KRYLKKI-RDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRS---GWKQEI 948
Query: 249 EIMKSLQHINIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKD 425
+I+++L H +I++ G DQG + L +VMEY+ GSL YL + ++ LL + +
Sbjct: 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
Query: 426 IATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPIN 605
I GM ++ A + +HRDLA RN+L+ N VKI DFGLA+ +P+ YR++ + P+
Sbjct: 1007 ICEGMAYLHAHDYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
Query: 606 WYAPESAVEPWHFSTKSDVWSYGVTAWEIFT 698
WYAPE ++ + F SDVWS+GVT +E+ T
Sbjct: 1067 WYAPE-CLKEYKFYYASDVWSFGVTLYELLT 1096
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Frame = +3
Query: 234 FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLK 413
F +M + H ++ + G +GPE +V EY+E G L+ +L+ + + ++ +
Sbjct: 655 FYETASLMSQVSHTHLAFVHGVCV-RGPENSMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+ +A+ + ++ KN+VH ++ RNIL+ + + + P + ER+
Sbjct: 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
Query: 594 LPINWYAPESAVEPWH-FSTKSDVWSYGVTAWEI 692
I W APE + ST D W +G T EI
Sbjct: 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 153 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 208
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 209 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 267
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 268 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 326
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 327 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 369
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 333 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 388
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 389 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 447
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 448 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 506
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 507 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 549
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 128 bits (310), Expect = 2e-29
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +++G G++G V++G + VA+K + AS R +F NE +MK
Sbjct: 1011 ITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERI---EFLNEASVMK 1067
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG +G L+VME + G L YL+ + + +++
Sbjct: 1068 GFTCHHVVRLLGVV-SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ 1126
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++AK VHRDLA RN +V + + VKI DFG+ R I E + YR + L
Sbjct: 1127 MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1185
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W APES ++ F+T SD+WS+GV WEI + A Q
Sbjct: 1186 LPVRWMAPES-LKDGVFTTSSDMWSFGVVLWEITSLAEQ 1223
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 128 bits (310), Expect = 2e-29
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +++G G++G V++G + VA+K + AS R +F NE +MK
Sbjct: 1023 ITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERI---EFLNEASVMK 1079
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG +G L+VME + G L YL+ + + +++
Sbjct: 1080 GFTCHHVVRLLGVV-SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ 1138
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++AK VHRDLA RN +V + + VKI DFG+ R I E + YR + L
Sbjct: 1139 MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1197
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W APES ++ F+T SD+WS+GV WEI + A Q
Sbjct: 1198 LPVRWMAPES-LKDGVFTTSSDMWSFGVVLWEITSLAEQ 1235
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 504 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 559
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 560 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 618
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 619 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 677
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 678 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 720
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 128 bits (310), Expect = 2e-29
Identities = 83/213 (38%), Positives = 120/213 (56%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K++G+G +G V WM N + +VAIK L + GT+ E F E +IMK
Sbjct: 273 LIKRLGNGQFGEV---WMGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 320
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 321 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 436
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 437 RALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 468
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 128 bits (310), Expect = 2e-29
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +++G G++G V++G + VA+K + AS R +F NE +MK
Sbjct: 1023 ITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERI---EFLNEASVMK 1079
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG +G L+VME + G L YL+ + + +++
Sbjct: 1080 GFTCHHVVRLLGVV-SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ 1138
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++AK VHRDLA RN +V + + VKI DFG+ R I E + YR + L
Sbjct: 1139 MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1197
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W APES ++ F+T SD+WS+GV WEI + A Q
Sbjct: 1198 LPVRWMAPES-LKDGVFTTSSDMWSFGVVLWEITSLAEQ 1235
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 128 bits (310), Expect = 2e-29
Identities = 75/223 (33%), Positives = 122/223 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G GN+G V+KG ++ + VA+K + L F E +I+K
Sbjct: 563 VILGELLGKGNFGEVYKGTLK------DKTSVAVKTCKEDLPQE---LKIKFLQEAKILK 613
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NIV+++G + P V I+ME + G +L+ + ++L++ L+K+ D A GM
Sbjct: 614 QYDHPNIVKLIGVCTQRQP-VYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGM 672
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ +KN +HRDLA RN LV +KISDFG++R ++ Y + +PI W APE
Sbjct: 673 LYLESKNCIHRDLAARNCLVGENNVLKISDFGMSR--QEDGGVYSSSGLKQIPIKWTAPE 730
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRER 749
A+ +S++SDVWS+G+ WE F+ P ++ RE+
Sbjct: 731 -ALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQ 772
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 128 bits (310), Expect = 2e-29
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 42 SLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWM-ERDNQESHRKEVAIKKLTRQASERNG 218
+++ +V + +V + IG G++G V+ G + + D ++ H A+K L R
Sbjct: 1083 AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIH---CAVKSLNRITDIGE- 1138
Query: 219 TLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRI 398
F E IMK H N++ +LG L+V+ Y++ G L +++ + +
Sbjct: 1139 --VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1196
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR-IIPKEENTYR 575
L+ + +A M ++++K VHRDLA RN ++ K+ VK++DFGLAR + KE +
Sbjct: 1197 KDLIGFGLQVAKAMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVH 1256
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
KT LP+ W A ES ++ F+TKSDVWS+GV WE+ TR P
Sbjct: 1257 NKTGAKLPVKWMALES-LQTQKFTTKSDVWSFGVVLWELMTRGAPPYP 1303
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 128 bits (310), Expect = 2e-29
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +++G G++G V++G + VA+K + AS R +F NE +MK
Sbjct: 1011 ITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERI---EFLNEASVMK 1067
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG +G L+VME + G L YL+ + + +++
Sbjct: 1068 GFTCHHVVRLLGVV-SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ 1126
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++AK VHRDLA RN +V + + VKI DFG+ R I E + YR + L
Sbjct: 1127 MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI-YETDYYRKGGKGL 1185
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W APES ++ F+T SD+WS+GV WEI + A Q
Sbjct: 1186 LPVRWMAPES-LKDGVFTTSSDMWSFGVVLWEITSLAEQ 1223
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 509 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 564
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 565 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 623
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 624 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 682
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 683 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 725
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 504 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 559
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 560 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 618
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 619 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 677
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 678 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 720
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 128 bits (310), Expect = 2e-29
Identities = 74/208 (35%), Positives = 115/208 (55%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V+KG ++ + VAIK L SE+ DF +E IM
Sbjct: 608 VKIEEVIGAGEFGEVYKGRLKLPGKREIY--VAIKTLKAGYSEKQR---RDFLSEASIMG 662
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 663 QFDHPNIIRLEGVVTKSRP-VMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 721
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +P+ W A
Sbjct: 722 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 781
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SDVWSYG+ WE+ +
Sbjct: 782 PE-AIAYRKFTSASDVWSYGIRMWEVMS 808
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 128 bits (310), Expect = 2e-29
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 9/219 (4%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +++G G++G V++G + VA+K + AS R +F NE +MK
Sbjct: 474 ITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERI---EFLNEASVMK 530
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR---------ISHLLK 413
++V +LG +G L+VME + G L YL+ + + +++
Sbjct: 531 GFTCHHVVRLLGVV-SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ 589
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+IA GM +++AK VHRDLA RN +V + + VKI DFG+ R I E + YR + L
Sbjct: 590 MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI-YETDYYRKGGKGL 648
Query: 594 LPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
LP+ W APES ++ F+T SD+WS+GV WEI + A Q
Sbjct: 649 LPVRWMAPES-LKDGVFTTSSDMWSFGVVLWEITSLAEQ 686
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 128 bits (310), Expect = 2e-29
Identities = 83/224 (37%), Positives = 119/224 (53%), Gaps = 14/224 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L ++G G +G VF E + VA+K L ++ASE + +DF+ E E++
Sbjct: 510 IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKAL-KEASE---SARQDFQREAELLT 565
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE--------------KLRI 398
LQH +IV G +G +L+V EY+ G LN +L+ G L +
Sbjct: 566 MLQHQHIVRFFGVC-TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL 624
Query: 399 SHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRL 578
LL +A GM +++ + VHRDLATRN LV VKI DFG++R I + YR+
Sbjct: 625 GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-YSTDYYRV 683
Query: 579 KTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 684 GGRTMLPIRWMPPESILYR-KFTTESDVWSFGVVLWEIFTYGKQ 726
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 128 bits (309), Expect = 3e-29
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+T+ K+G G YG V++G ++ + VA+K L E E+F E +MK
Sbjct: 242 ITMKHKLGGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMK 291
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATG 437
++H N+V++LG + P I+ E++ G+L YL+ +++ LL I++
Sbjct: 292 EIKHPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 350
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ KN +HRDLA RN LV + VK++DFGL+R++ + TY PI W AP
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAP 408
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
ES FS KSDVW++GV WEI T P D
Sbjct: 409 ESLAYN-KFSIKSDVWAFGVLLWEIATYGMSPYPGID 444
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 128 bits (309), Expect = 3e-29
Identities = 80/223 (35%), Positives = 125/223 (56%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+TL +IG G +G V +G E ++VA+K + + + F +E +M
Sbjct: 235 LTLGAQIGEGEFGAVLQG-------EYLGQKVAVKNIKCDVTA------QAFLDETAVMT 281
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLLKYCKDIATG 437
+QH N+V +LG QG + IVME++ +G+L +L+ +G L + LL++ +A G
Sbjct: 282 KMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +VHRDLA RNILV K+SDFGLA+ K ++ R LP+ W AP
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSR------LPVKWTAP 393
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
E+ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 394 EALKH--GFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 434
>BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein.
Length = 1187
Score = 128 bits (309), Expect = 3e-29
Identities = 74/211 (35%), Positives = 124/211 (58%), Gaps = 1/211 (0%)
Frame = +3
Query: 69 KTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNEL 248
K YL + + +G G++G V + N + + VA+K L ++ + +K E+
Sbjct: 894 KRYLKKI-RDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRS---GWKQEI 948
Query: 249 EIMKSLQHINIVEILGYAWDQGPEVL-IVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKD 425
+I+++L H +I++ G DQG + L +VMEY+ GSL YL + ++ LL + +
Sbjct: 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
Query: 426 IATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPIN 605
I GM ++ +++ +HRDLA RN+L+ N VKI DFGLA+ +P+ YR++ + P+
Sbjct: 1007 ICEGMAYLHSQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
Query: 606 WYAPESAVEPWHFSTKSDVWSYGVTAWEIFT 698
WYAPE ++ + F SDVWS+GVT +E+ T
Sbjct: 1067 WYAPE-CLKEYKFYYASDVWSFGVTLYELLT 1096
Score = 56.8 bits (131), Expect = 1e-07
Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = +3
Query: 234 FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLK 413
F +M + H ++ + G +GPE ++V EY+E G L+ +L+ + + ++ +
Sbjct: 655 FYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
Query: 414 YCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERL 593
+ +A+ + ++ KN+VH ++ RNIL+ + + + P + ER+
Sbjct: 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
Query: 594 LPINWYAPESAVEPWH-FSTKSDVWSYGVTAWEI 692
I W APE + ST D W +G T EI
Sbjct: 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 128 bits (308), Expect = 4e-29
Identities = 84/213 (39%), Positives = 115/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+G +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 247 LVERLGAGQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 294
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 295 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 352
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 410
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 411 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 442
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 128 bits (308), Expect = 4e-29
Identities = 84/213 (39%), Positives = 115/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+G +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 247 LVERLGAGQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 294
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 295 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 352
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 410
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 411 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 442
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 128 bits (308), Expect = 4e-29
Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 15/225 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L +++G G +G VF + + VA+K L + +DF+ E E++
Sbjct: 538 IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKAL----KDPTLAARKDFQREAELLT 593
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE---------------KLR 395
+LQH +IV+ G D P +++V EY++ G LN +L+ G +L
Sbjct: 594 NLQHEHIVKFYGVCGDGDP-LIMVFEYMKHGDLNKFLRAHGPNAMILVDGQPRQAKGELG 652
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
+S +L IA+GM ++++++ VHRDLATRN LV VKI DFG++R + + YR
Sbjct: 653 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYR 711
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ +LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 712 VGGHTMLPIRWMPPESIMYR-KFTTESDVWSFGVILWEIFTYGKQ 755
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 128 bits (308), Expect = 4e-29
Identities = 69/172 (40%), Positives = 106/172 (61%), Gaps = 1/172 (0%)
Frame = +3
Query: 234 FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKL-RISHLL 410
F +E +M +QH N+V +LG DQG + IVME++ +G+L +L+ +G L + LL
Sbjct: 231 FLDETAVMTKMQHENLVRLLGVILDQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLL 288
Query: 411 KYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTER 590
++ + GM+++ +K +VHRDLA RNILV + K+SDFGLA+ K ++ R
Sbjct: 289 QFSLHVREGMEYLESKKLVHRDLAARNILVSEELVAKVSDFGLAKAERKGLDSSR----- 343
Query: 591 LLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
LP+ W APE A++ F++KSDVWS+GV WE+F+ R PK ++ E
Sbjct: 344 -LPVKWTAPE-ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSE 393
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 226 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 273
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 274 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 332
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 333 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 390
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 391 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 424
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 128 bits (308), Expect = 4e-29
Identities = 72/200 (36%), Positives = 116/200 (58%)
Frame = +3
Query: 99 IGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHIN 278
IG G +G V++G + +Q+ K VAIK L + G + +F E IM H +
Sbjct: 638 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSP---GGQWWNFLREATIMGQFSHPH 692
Query: 279 IVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAK 458
I+ + G + P ++I+ E++E +L+ +L+ + ++L L+ + IA+GM+++S
Sbjct: 693 ILHLEGVVTKRKP-IMIITEFMENAALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 751
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N VHRDLA RNILV K+SDFGL R++ + TY + + +PI W APE A+
Sbjct: 752 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPE-AIAHR 809
Query: 639 HFSTKSDVWSYGVTAWEIFT 698
F+T SDVWS+G+ WE+ +
Sbjct: 810 IFTTASDVWSFGIVMWEVLS 829
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 294
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 295 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 411
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 412 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 445
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 294
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 295 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 411
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 412 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 445
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 294
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 295 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 411
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 412 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 445
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 128 bits (308), Expect = 4e-29
Identities = 73/208 (35%), Positives = 115/208 (55%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V+KG ++ + VAIK L SE+ DF +E IM
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIY--VAIKTLKAGYSEKQR---RDFLSEASIMG 673
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 674 QFDHPNIIRLEGVVTKSRP-VMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNIL+ + K+SDFGL+R + + + TY +P+ W A
Sbjct: 733 KYLAEMNYVHRDLAARNILLNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SDVWSYG+ WE+ +
Sbjct: 793 PE-AIAYRKFTSASDVWSYGIVMWEVMS 819
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 294
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 295 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 411
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 412 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 445
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 294
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 295 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 411
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 412 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 445
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 364
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 365 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 423
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 424 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 481
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 482 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 515
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 128 bits (308), Expect = 4e-29
Identities = 77/215 (35%), Positives = 118/215 (54%), Gaps = 2/215 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTL-YEDFKNELEIM 257
+ L K++G+G +G V+ G+ + VA+K L + GT+ + F E +M
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTK------VAVKTL------KPGTMSVQAFLEEANLM 364
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIAT 434
K+LQH +V + + P + I+ EY+ +GSL +LK +G K+ + L+ + IA
Sbjct: 365 KTLQHDKLVRLYAVVTREEP-IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 423
Query: 435 GMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYA 614
GM ++ KN +HRDL N+LV KI+DFGLAR+I E+N Y + PI W A
Sbjct: 424 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVI--EDNEYTAREGAKFPIKWTA 481
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
PE A+ F+ KSDVWS+G+ +EI T + P
Sbjct: 482 PE-AINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 515
>AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 128 bits (308), Expect = 4e-29
Identities = 84/213 (39%), Positives = 115/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+G +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 234 LVERLGAGQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 281
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 282 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 339
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 340 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 397
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 398 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 429
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 128 bits (308), Expect = 4e-29
Identities = 84/213 (39%), Positives = 115/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+G +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 234 LVERLGAGQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 281
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 282 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 339
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 340 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 397
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 398 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 429
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 128 bits (308), Expect = 4e-29
Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 15/225 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L +++G G +G VF + + VA+K L + +DF+ E E++
Sbjct: 31 IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKAL----KDPTLAARKDFQREAELLT 86
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE---------------KLR 395
+LQH +IV+ G D P +++V EY++ G LN +L+ G +L
Sbjct: 87 NLQHEHIVKFYGVCGDGDP-LIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELG 145
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
+S +L IA+GM ++++++ VHRDLATRN LV VKI DFG++R + + YR
Sbjct: 146 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYR 204
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ +LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 205 VGGHTMLPIRWMPPESIMYR-KFTTESDVWSFGVILWEIFTYGKQ 248
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 128 bits (308), Expect = 4e-29
Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 15/225 (6%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ L +++G G +G VF + + VA+K L + +DF+ E E++
Sbjct: 121 IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKAL----KDPTLAARKDFQREAELLT 176
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGE---------------KLR 395
+LQH +IV+ G D P +++V EY++ G LN +L+ G +L
Sbjct: 177 NLQHEHIVKFYGVCGDGDP-LIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELG 235
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
+S +L IA+GM ++++++ VHRDLATRN LV VKI DFG++R + + YR
Sbjct: 236 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYR 294
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
+ +LPI W PES + F+T+SDVWS+GV WEIFT +Q
Sbjct: 295 VGGHTMLPIRWMPPESIMYR-KFTTESDVWSFGVILWEIFTYGKQ 338
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 128 bits (308), Expect = 4e-29
Identities = 74/206 (35%), Positives = 114/206 (55%), Gaps = 2/206 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V+KG ++ + VAIK L SE+ DF +E IM
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIY--VAIKTLKAGYSEKQR---RDFLSEASIMG 673
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 674 QFDHPNIIRLEGVVTKSRP-VMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +P+ W A
Sbjct: 733 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEI 692
PE A+ F++ SDVWSYG+ WE+
Sbjct: 793 PE-AIAYRKFTSASDVWSYGIHMWEV 817
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine kinase
protein.
Length = 1037
Score = 127 bits (307), Expect = 5e-29
Identities = 75/229 (32%), Positives = 117/229 (51%)
Frame = +3
Query: 6 FLTTHYREFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIK 185
++ H E ++ + + +T+ + IG+G +G V G ++ + VAIK
Sbjct: 650 YIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRE--LPVAIK 707
Query: 186 KLTRQASERNGTLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNY 365
L +E+ DF E IM H NI+ + G P V+IV EY+E GSL+
Sbjct: 708 TLKVGYTEKQR---RDFLGEASIMGQFDHPNIIHLEGVVTKSKP-VMIVTEYMENGSLDT 763
Query: 366 YLKFQGEKLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR 545
+LK + + L+ + I+ GM ++S VHRDLA RNIL+ + K+SDFGL+R
Sbjct: 764 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 823
Query: 546 IIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEI 692
++ + +PI W APE A+ F++ SDVWSYG+ WE+
Sbjct: 824 VLEDDPEAAYTTRGGKIPIRWTAPE-AIAFRKFTSASDVWSYGIVMWEV 871
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 127 bits (307), Expect = 5e-29
Identities = 84/213 (39%), Positives = 115/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+G +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 250 LVERLGAGQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 297
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 298 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 355
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 356 VFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 413
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 414 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 445
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 127 bits (307), Expect = 5e-29
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+++ K +G+G +G V G ++ +++ VAIK L +E+ DF E IM
Sbjct: 621 ISIDKVVGAGEFGEVCSGRLKLPSKKEI--SVAIKTLKVGYTEKQR---RDFLGEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+IV EY+E GSL+ +L+ + + L+ + IA+GM
Sbjct: 676 QFDHPNIIRLEGVVTKSKP-VMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++S VHRDLA RNIL+ + K+SDFGL+R++ + +PI W +PE
Sbjct: 735 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPE 794
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A+ F++ SDVWSYG+ WE+ +
Sbjct: 795 -AIAYRKFTSASDVWSYGIVLWEVMS 819
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 127 bits (307), Expect = 5e-29
Identities = 75/229 (32%), Positives = 117/229 (51%)
Frame = +3
Query: 6 FLTTHYREFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIK 185
++ H E ++ + + +T+ + IG+G +G V G ++ + VAIK
Sbjct: 604 YIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRE--LPVAIK 661
Query: 186 KLTRQASERNGTLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNY 365
L +E+ DF E IM H NI+ + G P V+IV EY+E GSL+
Sbjct: 662 TLKVGYTEKQR---RDFLGEASIMGQFDHPNIIHLEGVVTKSKP-VMIVTEYMENGSLDT 717
Query: 366 YLKFQGEKLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR 545
+LK + + L+ + I+ GM ++S VHRDLA RNIL+ + K+SDFGL+R
Sbjct: 718 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 777
Query: 546 IIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEI 692
++ + +PI W APE A+ F++ SDVWSYG+ WE+
Sbjct: 778 VLEDDPEAAYTTRGGKIPIRWTAPE-AIAFRKFTSASDVWSYGIVMWEV 825
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 127 bits (307), Expect = 5e-29
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+++ K +G+G +G V G ++ +++ VAIK L +E+ DF E IM
Sbjct: 621 ISIDKVVGAGEFGEVCSGRLKLPSKKEI--SVAIKTLKVGYTEKQR---RDFLGEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+IV EY+E GSL+ +L+ + + L+ + IA+GM
Sbjct: 676 QFDHPNIIRLEGVVTKSKP-VMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++S VHRDLA RNIL+ + K+SDFGL+R++ + +PI W +PE
Sbjct: 735 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPE 794
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A+ F++ SDVWSYG+ WE+ +
Sbjct: 795 -AIAYRKFTSASDVWSYGIVLWEVMS 819
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 127 bits (307), Expect = 5e-29
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+++ K +G+G +G V G ++ +++ VAIK L +E+ DF E IM
Sbjct: 621 ISIDKVVGAGEFGEVCSGRLKLPSKKEI--SVAIKTLKVGYTEKQR---RDFLGEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+IV EY+E GSL+ +L+ + + L+ + IA+GM
Sbjct: 676 QFDHPNIIRLEGVVTKSKP-VMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++S VHRDLA RNIL+ + K+SDFGL+R++ + +PI W +PE
Sbjct: 735 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPE 794
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A+ F++ SDVWSYG+ WE+ +
Sbjct: 795 -AIAYRKFTSASDVWSYGIVLWEVMS 819
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 127 bits (307), Expect = 5e-29
Identities = 77/231 (33%), Positives = 124/231 (53%), Gaps = 1/231 (0%)
Frame = +3
Query: 39 ISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNG 218
+SL + + + K +TL K++GSG +G V G + + +VA+K + + G
Sbjct: 425 VSLANGIWELKREEITLLKELGSGQFGVVQLG------KWKGQYDVAVKMI------KEG 472
Query: 219 TLYED-FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR 395
++ ED F E + M L H +V+ G + P + IV EY+ G L YL+ G+ L
Sbjct: 473 SMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYP-IYIVTEYISNGCLLNYLRSHGKGLE 531
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
S LL+ C D+ GM + + +HRDLA RN LV VK+SDFG+ R + ++
Sbjct: 532 PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSS 591
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
+ T+ P+ W APE + +S+KSDVW++G+ WE+F+ +Q +D
Sbjct: 592 VGTK--FPVKWSAPE-VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYD 639
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 127 bits (307), Expect = 5e-29
Identities = 75/229 (32%), Positives = 117/229 (51%)
Frame = +3
Query: 6 FLTTHYREFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIK 185
++ H E ++ + + +T+ + IG+G +G V G ++ + VAIK
Sbjct: 664 YIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRE--LPVAIK 721
Query: 186 KLTRQASERNGTLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNY 365
L +E+ DF E IM H NI+ + G P V+IV EY+E GSL+
Sbjct: 722 TLKVGYTEKQR---RDFLGEASIMGQFDHPNIIHLEGVVTKSKP-VMIVTEYMENGSLDT 777
Query: 366 YLKFQGEKLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR 545
+LK + + L+ + I+ GM ++S VHRDLA RNIL+ + K+SDFGL+R
Sbjct: 778 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 837
Query: 546 IIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEI 692
++ + +PI W APE A+ F++ SDVWSYG+ WE+
Sbjct: 838 VLEDDPEAAYTTRGGKIPIRWTAPE-AIAFRKFTSASDVWSYGIVMWEV 885
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 127 bits (306), Expect = 7e-29
Identities = 77/231 (33%), Positives = 124/231 (53%), Gaps = 1/231 (0%)
Frame = +3
Query: 39 ISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNG 218
+SL + + + K +TL K++GSG +G V G + + +VA+K + + G
Sbjct: 403 VSLGNGIWELKREEITLLKELGSGQFGVVQLG------KWKGQYDVAVKMI------KEG 450
Query: 219 TLYED-FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR 395
++ ED F E + M L H +V+ G + P + IV EY+ G L YL+ G+ L
Sbjct: 451 SMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYP-IYIVTEYISNGCLLNYLRSHGKGLE 509
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
S LL+ C D+ GM + + +HRDLA RN LV VK+SDFG+ R + ++
Sbjct: 510 PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSS 569
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
+ T+ P+ W APE + +S+KSDVW++G+ WE+F+ +Q +D
Sbjct: 570 VGTK--FPVKWSAPE-VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYD 617
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 127 bits (306), Expect = 7e-29
Identities = 77/231 (33%), Positives = 124/231 (53%), Gaps = 1/231 (0%)
Frame = +3
Query: 39 ISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNG 218
+SL + + + K +TL K++GSG +G V G + + +VA+K + + G
Sbjct: 403 VSLGNGIWELKREEITLLKELGSGQFGVVQLG------KWKGQYDVAVKMI------KEG 450
Query: 219 TLYED-FKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLR 395
++ ED F E + M L H +V+ G + P + IV EY+ G L YL+ G+ L
Sbjct: 451 SMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYP-IYIVTEYISNGCLLNYLRSHGKGLE 509
Query: 396 ISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYR 575
S LL+ C D+ GM + + +HRDLA RN LV VK+SDFG+ R + ++
Sbjct: 510 PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSS 569
Query: 576 LKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFD 728
+ T+ P+ W APE + +S+KSDVW++G+ WE+F+ +Q +D
Sbjct: 570 VGTK--FPVKWSAPE-VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYD 617
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 400 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 447
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 448 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 506
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 507 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 564
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 565 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 599
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 126 bits (304), Expect = 1e-28
Identities = 79/205 (38%), Positives = 109/205 (53%)
Frame = +3
Query: 93 KKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQH 272
K+IGSG +G V G SH +VAIK + + EDF E ++M L H
Sbjct: 275 KEIGSGQFGVVHLG-----EWRSHI-QVAIKAINEGSMSE-----EDFIEEAKVMMKLSH 323
Query: 273 INIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVS 452
+V++ G + P + IV E++E G L YL+ KLR LL C+DI GM+++
Sbjct: 324 SKLVQLYGVCIQRKP-LYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLE 382
Query: 453 AKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVE 632
+HRDLA RN LV + VKISDFG+ R + +E Y PI W PE +
Sbjct: 383 RNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDE--YVSSFGAKFPIKWSPPEVFLF 440
Query: 633 PWHFSTKSDVWSYGVTAWEIFTRAR 707
+S+KSDVWS+GV WE+FT +
Sbjct: 441 N-KYSSKSDVWSFGVLMWEVFTEGK 464
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 73 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 120
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 121 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 179
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 180 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 237
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 238 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 272
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 633 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 807 -AIQYRKFTSASDVWSYGIVMWEVMS 831
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 126 bits (304), Expect = 1e-28
Identities = 72/216 (33%), Positives = 122/216 (56%), Gaps = 1/216 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIM 257
+T K++G+G +G V G + + +VAIK + + G++ ED F E ++M
Sbjct: 402 LTFLKELGTGQFGVVKYG------KWRGQYDVAIKMI------KEGSMSEDEFIEEAKVM 449
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATG 437
+L H +V++ G Q P + I+ EY+ G L YL+ + + LL+ CKD+
Sbjct: 450 MNLSHEKLVQLYGVCTKQRP-IFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEA 508
Query: 438 MDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAP 617
M+++ +K +HRDLA RN LV ++ VK+SDFGL+R + +E T + ++ P+ W P
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSK--FPVRWSPP 566
Query: 618 ESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKF 725
E + FS+KSD+W++GV WEI++ + +F
Sbjct: 567 EVLMYS-KFSSKSDIWAFGVLMWEIYSLGKMPYERF 601
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 126 bits (304), Expect = 1e-28
Identities = 71/206 (34%), Positives = 113/206 (54%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + + IG+G +G V G ++ + VAIK L +E+ DF E IM
Sbjct: 635 IKIERVIGAGEFGEVCSGRLKLPGKRD--VAVAIKTLKVGYTEKQR---RDFLCEASIMG 689
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N+V + G +G V+IV+E++E G+L+ +L+ + + L+ + IA GM
Sbjct: 690 QFDHPNVVHLEGVV-TRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 748
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+++ VHRDLA RNILV + K+SDFGL+R+I + T +P+ W APE
Sbjct: 749 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 808
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFT 698
A++ F++ SDVWSYG+ WE+ +
Sbjct: 809 -AIQYRKFTSASDVWSYGIVMWEVMS 833
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 676
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 677 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 736 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 795
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 796 PE-AIQYRKFTSASDVWSYGIVMWEVMS 822
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 113 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 167
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 168 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 226
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 227 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 286
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 287 PE-AIQYRKFTSASDVWSYGIVMWEVMS 313
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 670
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 671 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 730 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 789
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 790 PE-AIQYRKFTSASDVWSYGIVMWEVMS 816
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 676
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 677 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 736 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 795
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 796 PE-AIQYRKFTSASDVWSYGIVMWEVMS 822
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 670
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 671 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 730 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 789
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 790 PE-AIQYRKFTSASDVWSYGIVMWEVMS 816
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 676
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 677 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 736 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 795
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 796 PE-AIQYRKFTSASDVWSYGIVMWEVMS 822
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 676
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 677 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 736 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 795
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 796 PE-AIQYRKFTSASDVWSYGIVMWEVMS 822
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 670
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 671 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 730 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 789
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 790 PE-AIQYRKFTSASDVWSYGIVMWEVMS 816
>AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein.
Length = 1005
Score = 126 bits (303), Expect = 2e-28
Identities = 76/204 (37%), Positives = 109/204 (53%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + K IGSG+ G V G + Q VAIK L +ER DF +E IM
Sbjct: 635 IHIEKIIGSGDSGEVCYGRLRVPGQRD--VPVAIKALKAGYTERQR---RDFLSEASIMG 689
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G +G +IV EY+E GSL+ +L+ + I L+ + + GM
Sbjct: 690 QFDHPNIIRLEGVV-TRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGM 748
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++S VHRDLA RN+LV + K+SDFGL+R++ + + T +PI W APE
Sbjct: 749 RYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPE 808
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEI 692
A+ FS+ SDVWS+GV WE+
Sbjct: 809 -AIAFRTFSSASDVWSFGVVMWEV 831
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 675
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 676 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 795 PE-AIQYRKFTSASDVWSYGIVMWEVMS 821
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 126 bits (303), Expect = 2e-28
Identities = 73/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 639 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 693
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 694 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 752
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 753 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 812
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 813 PE-AIQYRKFTSASDVWSYGIVMWEVMS 839
>AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein.
Length = 853
Score = 126 bits (303), Expect = 2e-28
Identities = 76/204 (37%), Positives = 109/204 (53%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
+ + K IGSG+ G V G + Q VAIK L +ER DF +E IM
Sbjct: 483 IHIEKIIGSGDSGEVCYGRLRVPGQRD--VPVAIKALKAGYTERQR---RDFLSEASIMG 537
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G +G +IV EY+E GSL+ +L+ + I L+ + + GM
Sbjct: 538 QFDHPNIIRLEGVV-TRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGM 596
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++S VHRDLA RN+LV + K+SDFGL+R++ + + T +PI W APE
Sbjct: 597 RYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPE 656
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEI 692
A+ FS+ SDVWS+GV WE+
Sbjct: 657 -AIAFRTFSSASDVWSFGVVMWEV 679
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 125 bits (302), Expect = 2e-28
Identities = 82/213 (38%), Positives = 119/213 (55%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L KK+G G + V W+ N + +VAIK L + GT+ E F E +IMK
Sbjct: 221 LEKKLGQGCFAEV---WLGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 268
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 269 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 326
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 327 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 384
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 385 AALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 416
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 125 bits (302), Expect = 2e-28
Identities = 82/213 (38%), Positives = 119/213 (55%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L KK+G G + V W+ N + +VAIK L + GT+ E F E +IMK
Sbjct: 270 LEKKLGQGCFAEV---WLGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 317
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 318 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 375
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 376 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 433
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 434 AALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 465
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 83/213 (38%), Positives = 114/213 (53%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYED-FKNELEIMKS 263
L +++G+ +G V+ G+ H K VA+K L + G++ D F E +MK
Sbjct: 247 LVERLGAAQFGEVWMGYYN-----GHTK-VAVKSL------KQGSMSPDAFLAEANLMKQ 294
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
LQH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 295 LQHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM 352
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE 410
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 411 -AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 442
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 1939 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 1995
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 1996 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 2054
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 2055 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 2113
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 2114 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 2157
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 1945 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 2001
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 2002 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 2060
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 2061 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 2119
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 2120 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 2163
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 125 bits (301), Expect = 3e-28
Identities = 74/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G +++ + VAIK L +ER DF +E IM
Sbjct: 633 VKIEEVIGAGEFGEVCRGRLKQPGRRE--VFVAIKTLKVGYTERQR---RDFLSEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E +L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNIIRLEGVVTKSRP-VMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
++S N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SDVWSYG+ WE+ +
Sbjct: 807 PE-AIAYRKFTSASDVWSYGIVMWEVMS 833
>U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta
protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGLFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal
tyrosine kinase protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 1945 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 2001
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 2002 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 2060
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 2061 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 2119
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 2120 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 2163
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 92 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 148
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 149 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 207
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 208 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 266
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 267 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 310
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 156 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 212
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 213 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 271
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 272 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 330
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 331 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 374
>L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 125 bits (301), Expect = 3e-28
Identities = 73/208 (35%), Positives = 113/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V G ++ + VAIK L +E+ DF +E IM
Sbjct: 605 VKIEQVIGAGEFGEVCSGHLKLPGKREIF--VAIKTLKSGYTEKQR---RDFLSEASIMG 659
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H N++ + G P V+I+ E++E GSL+ +L+ + + L+ + IA GM
Sbjct: 660 QFDHPNVIHLEGVVTKSTP-VMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 718
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
+++ N VHRDLA RNILV + K+SDFGL+R + + + TY PI W A
Sbjct: 719 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKFPIRWTA 778
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A++ F++ SDVWSYG+ WE+ +
Sbjct: 779 PE-AIQYRKFTSASDVWSYGIVMWEVMS 805
>L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kinase
protein.
Length = 1036
Score = 125 bits (301), Expect = 3e-28
Identities = 76/209 (36%), Positives = 114/209 (54%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L +K+G G++G V +G E D VA+K L + + +DF E+ M SL
Sbjct: 128 LLEKLGDGSFGVVRRG--EWDAPSGKTVSVAVKCLKPDVLSQPEAM-DDFIREVNAMHSL 184
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYL-KFQGEKLRISHLLKYCKDIATGMD 443
H N++ + G P + +V E GSL L K QG L + L +Y +A GM
Sbjct: 185 DHRNLIRLYGVVLT--PPMKMVTELAPLGSLLDRLRKHQGHFL-LGTLSRYAVQVAEGMG 241
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ +K +HRDLA RN+L+ + VKI DFGL R +P+ ++ Y ++ R +P W APES
Sbjct: 242 YLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPES 301
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
++ FS SD W +GVT WE+FT ++
Sbjct: 302 -LKTRTFSHASDTWMFGVTLWEMFTYGQE 329
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 125 bits (301), Expect = 3e-28
Identities = 74/208 (35%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G +++ + VAIK L +ER DF +E IM
Sbjct: 633 VKIEEVIGAGEFGEVCRGRLKQPGRRE--VFVAIKTLKVGYTERQR---RDFLSEASIMG 687
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
H NI+ + G P V+I+ E++E +L+ +L+ + + L+ + IA GM
Sbjct: 688 QFDHPNIIRLEGVVTKSRP-VMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKE--ENTYRLKTERLLPINWYA 614
++S N VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SDVWSYG+ WE+ +
Sbjct: 807 PE-AIAYRKFTSASDVWSYGIVMWEVMS 833
>BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 425 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 479
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 480 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 537
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 538 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 595
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 596 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 624
>BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein.
Length = 528
Score = 125 bits (301), Expect = 3e-28
Identities = 76/209 (36%), Positives = 114/209 (54%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L +K+G G++G V +G E D VA+K L + + +DF E+ M SL
Sbjct: 128 LLEKLGDGSFGVVRRG--EWDAPSGKTVSVAVKCLKPDVLSQPEAM-DDFIREVNAMHSL 184
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYL-KFQGEKLRISHLLKYCKDIATGMD 443
H N++ + G P + +V E GSL L K QG L + L +Y +A GM
Sbjct: 185 DHRNLIRLYGVVLT--PPMKMVTELAPLGSLLDRLRKHQGHFL-LGTLSRYAVQVAEGMG 241
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ +K +HRDLA RN+L+ + VKI DFGL R +P+ ++ Y ++ R +P W APES
Sbjct: 242 YLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPES 301
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
++ FS SD W +GVT WE+FT ++
Sbjct: 302 -LKTRTFSHASDTWMFGVTLWEMFTYGQE 329
>AL132671-5|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 1939 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 1995
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 1996 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 2054
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 2055 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 2113
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 2114 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 2157
>AL132671-4|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 125 bits (301), Expect = 3e-28
Identities = 83/225 (36%), Positives = 123/225 (54%), Gaps = 12/225 (5%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGW-MERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIM 257
+TL +GSG +G V++G ++ S +VA+K L + ++++ +F E +M
Sbjct: 1945 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKI---EFLKEAHLM 2001
Query: 258 KSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLK------FQGEKLRISHLLKYC 419
H NI++ LG P+ I++E +E G L YL+ F G L + L+ C
Sbjct: 2002 SKFNHPNILKQLGVCLLNEPQY-IILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLC 2060
Query: 420 KDIATGMDHVSAKNVVHRDLATRNILVVNKYH-----VKISDFGLARIIPKEENTYRLKT 584
DI+ G ++ + +HRDLA RN LV K + VKI DFGLAR I K + YR +
Sbjct: 2061 VDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDY-YRKRG 2119
Query: 585 ERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
E LLP+ W APES ++ F+T+SDVWS+G+ WEI T Q P
Sbjct: 2120 EGLLPVRWMAPESLMDGI-FTTQSDVWSFGILIWEILTLGHQPYP 2163
>AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens
cDNA FLJ16772 fis, clone BRAWH3043827, highly similar
to Homo sapiens activated p21cdc42Hs kinase (ACK1). ).
Length = 1086
Score = 125 bits (301), Expect = 3e-28
Identities = 76/209 (36%), Positives = 114/209 (54%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L +K+G G++G V +G E D VA+K L + + +DF E+ M SL
Sbjct: 191 LLEKLGDGSFGVVRRG--EWDAPSGKTVSVAVKCLKPDVLSQPEAM-DDFIREVNAMHSL 247
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYL-KFQGEKLRISHLLKYCKDIATGMD 443
H N++ + G P + +V E GSL L K QG L + L +Y +A GM
Sbjct: 248 DHRNLIRLYGVVLT--PPMKMVTELAPLGSLLDRLRKHQGHFL-LGTLSRYAVQVAEGMG 304
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ +K +HRDLA RN+L+ + VKI DFGL R +P+ ++ Y ++ R +P W APES
Sbjct: 305 YLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPES 364
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
++ FS SD W +GVT WE+FT ++
Sbjct: 365 -LKTRTFSHASDTWMFGVTLWEMFTYGQE 392
>AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens
cDNA FLJ46514 fis, clone THYMU3032798, highly similar
to Focal adhesion kinase 2 (EC 2.7.1.112). ).
Length = 596
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 171 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 225
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 226 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 283
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 284 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 341
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 342 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 370
>AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine
kinase 2 beta isoform a variant protein.
Length = 802
Score = 125 bits (301), Expect = 3e-28
Identities = 75/210 (35%), Positives = 116/210 (55%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V L + +G G +G V++G N + + VA+K + + N E F +E IMK
Sbjct: 430 VVLNRILGEGFFGEVYEGVYT--NHKGEKINVAVKTCKKDCTLDNK---EKFMSEAVIMK 484
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+L H +IV+++G ++ I+ME G L +YL+ L++ L+ Y I M
Sbjct: 485 NLDHPHIVKLIGIIEEE--PTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAM 542
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ + N VHRD+A RNILV + VK+ DFGL+R I ++E+ Y+ R LPI W +PE
Sbjct: 543 AYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVTR-LPIKWMSPE 600
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQ 710
S + F+T SDVW + V WEI + +Q
Sbjct: 601 S-INFRRFTTASDVWMFAVCMWEILSFGKQ 629
>X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA fragment
for epidermal growth factor (EGF) receptor. ).
Length = 800
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 574 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 628
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 629 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 686
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 687 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 745
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 746 HR-IYTHQSDVWSYGVTVWELMT 767
>X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor
receptor protein.
Length = 1210
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 716 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 770
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 771 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 828
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 829 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 887
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 888 HR-IYTHQSDVWSYGVTVWELMT 909
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 124 bits (300), Expect = 4e-28
Identities = 82/213 (38%), Positives = 118/213 (55%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L KK+G G + V W+ N + +VAIK L + GT+ E F E +IMK
Sbjct: 270 LEKKLGQGCFAEV---WLGTWNGNT---KVAIKTL------KPGTMSPESFLEEAQIMKK 317
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK +G L++ +L+ +A GM
Sbjct: 318 LKHDKLVQL--YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 375
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
++ N +HRDL + NILV N KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 376 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQGAKFPIKWTAPE 433
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 434 RALY-GRFTIKSDVWSFGILLTELVTKGRVPYP 465
>BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein.
Length = 1091
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 671 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 725
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 726 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 783
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 784 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 842
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 843 HR-IYTHQSDVWSYGVTVWELMT 864
>AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor
receptor (erythroblastic leukemia viral (v-erb-b) oncog
protein.
Length = 1210
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 716 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 770
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 771 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 828
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 829 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 887
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 888 HR-IYTHQSDVWSYGVTVWELMT 909
>AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting
protein 40 protein.
Length = 1210
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 716 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 770
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 771 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 828
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 829 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 887
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 888 HR-IYTHQSDVWSYGVTVWELMT 909
>AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth factor
receptor protein.
Length = 1210
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 716 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 770
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 771 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 828
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 829 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 887
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 888 HR-IYTHQSDVWSYGVTVWELMT 909
>AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor
receptor isoform a variant protein.
Length = 1081
Score = 124 bits (300), Expect = 4e-28
Identities = 72/203 (35%), Positives = 116/203 (57%), Gaps = 1/203 (0%)
Frame = +3
Query: 93 KKIGSGNYGHVFKG-WMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQ 269
K +GSG +G V+KG W+ E + VAIK+L S + ++ +E +M S+
Sbjct: 587 KVLGSGAFGTVYKGLWIPEG--EKVKIPVAIKELREATSPKAN---KEILDEAYVMASVD 641
Query: 270 HINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHV 449
+ ++ +LG V ++ + + G L Y++ + + +LL +C IA GM+++
Sbjct: 642 NPHVCRLLGICLTS--TVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYL 699
Query: 450 SAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAV 629
+ +VHRDLA RN+LV HVKI+DFGLA+++ EE Y + + +PI W A ES +
Sbjct: 700 EDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGK-VPIKWMALESIL 758
Query: 630 EPWHFSTKSDVWSYGVTAWEIFT 698
++ +SDVWSYGVT WE+ T
Sbjct: 759 HR-IYTHQSDVWSYGVTVWELMT 780
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein
protein.
Length = 969
Score = 124 bits (299), Expect = 5e-28
Identities = 74/229 (32%), Positives = 116/229 (50%)
Frame = +3
Query: 6 FLTTHYREFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIK 185
++ H E ++ + + +T+ + IG+G +G V G ++ + VAIK
Sbjct: 582 YIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRE--LPVAIK 639
Query: 186 KLTRQASERNGTLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNY 365
L +E+ DF E IM H NI+ + G P V+IV EY+E GSL+
Sbjct: 640 TLKVGYTEKQR---RDFLGEASIMGQFDHPNIIHLEGVVTKSKP-VMIVTEYMENGSLDT 695
Query: 366 YLKFQGEKLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLAR 545
+LK + + L+ + I+ GM ++S VHRDLA RNIL+ + K+SDF L+R
Sbjct: 696 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFELSR 755
Query: 546 IIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEI 692
++ + +PI W APE A+ F++ SDVWSYG+ WE+
Sbjct: 756 VLEDDPEAAYTTRGGKIPIRWTAPE-AIAFRKFTSASDVWSYGIVMWEV 803
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 124 bits (299), Expect = 5e-28
Identities = 81/240 (33%), Positives = 135/240 (56%), Gaps = 9/240 (3%)
Frame = +3
Query: 27 EFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQAS 206
E L+ LE +V L+ L K +G G +G V +G +++++ S + V KL +S
Sbjct: 395 EELQNKLEDVVIDRN--LLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDN-SS 451
Query: 207 ERNGTLYEDFKNELEIMKSLQHINIVEILGYAWD---QG-PEVLIVMEYLEEGSLNYYLK 374
+R E+F +E MK H N++ +LG + QG P+ ++++ +++ G L+ YL
Sbjct: 452 QRE---IEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLL 508
Query: 375 FQ----GEK-LRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGL 539
+ G K + + LLK+ DIA GM+++S +N +HRDLA RN ++ + V ++DFGL
Sbjct: 509 YSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGL 568
Query: 540 ARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
++ I + YR +P+ W A ES + +++KSDVW++GVT WEI TR P
Sbjct: 569 SKKI-YSGDYYRQGRIAKMPVKWIAIESLADR-VYTSKSDVWAFGVTMWEIATRGMTPYP 626
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 124 bits (299), Expect = 5e-28
Identities = 81/240 (33%), Positives = 135/240 (56%), Gaps = 9/240 (3%)
Frame = +3
Query: 27 EFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQAS 206
E L+ LE +V L+ L K +G G +G V +G +++++ S + V KL +S
Sbjct: 395 EELQNKLEDVVIDRN--LLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDN-SS 451
Query: 207 ERNGTLYEDFKNELEIMKSLQHINIVEILGYAWD---QG-PEVLIVMEYLEEGSLNYYLK 374
+R E+F +E MK H N++ +LG + QG P+ ++++ +++ G L+ YL
Sbjct: 452 QRE---IEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLL 508
Query: 375 FQ----GEK-LRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGL 539
+ G K + + LLK+ DIA GM+++S +N +HRDLA RN ++ + V ++DFGL
Sbjct: 509 YSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGL 568
Query: 540 ARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
++ I + YR +P+ W A ES + +++KSDVW++GVT WEI TR P
Sbjct: 569 SKKI-YSGDYYRQGRIAKMPVKWIAIESLADR-VYTSKSDVWAFGVTMWEIATRGMTPYP 626
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 124 bits (299), Expect = 5e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 1/217 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L + IG G +G V G + +VA+K + +N + F E +M L
Sbjct: 197 LLQTIGKGEFGDVMLG-------DYRGNKVAVKCI------KNDATAQAFLAEASVMTQL 243
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEK-LRISHLLKYCKDIATGMD 443
+H N+V++LG ++ + IV EY+ +GSL YL+ +G L LLK+ D+ M+
Sbjct: 244 RHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAME 303
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
++ N VHRDLA RN+LV K+SDFGL + ++T + LP+ W APE
Sbjct: 304 YLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGK------LPVKWTAPE- 356
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVE 734
A+ FSTKSDVWS+G+ WEI++ R P+ ++
Sbjct: 357 ALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK 393
>AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine kinase
protein.
Length = 978
Score = 124 bits (299), Expect = 5e-28
Identities = 81/240 (33%), Positives = 135/240 (56%), Gaps = 9/240 (3%)
Frame = +3
Query: 27 EFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQAS 206
E L+ LE +V L+ L K +G G +G V +G +++++ S + V KL +S
Sbjct: 550 EELQNKLEDVVIDRN--LLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDN-SS 606
Query: 207 ERNGTLYEDFKNELEIMKSLQHINIVEILGYAWD---QG-PEVLIVMEYLEEGSLNYYLK 374
+R E+F +E MK H N++ +LG + QG P+ ++++ +++ G L+ YL
Sbjct: 607 QRE---IEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLL 663
Query: 375 FQ----GEK-LRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGL 539
+ G K + + LLK+ DIA GM+++S +N +HRDLA RN ++ + V ++DFGL
Sbjct: 664 YSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGL 723
Query: 540 ARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
++ I + YR +P+ W A ES + +++KSDVW++GVT WEI TR P
Sbjct: 724 SKKI-YSGDYYRQGRIAKMPVKWIAIESLADR-VYTSKSDVWAFGVTMWEIATRGMTPYP 781
>AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein.
Length = 567
Score = 124 bits (299), Expect = 5e-28
Identities = 81/240 (33%), Positives = 135/240 (56%), Gaps = 9/240 (3%)
Frame = +3
Query: 27 EFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQAS 206
E L+ LE +V L+ L K +G G +G V +G +++++ S + V KL +S
Sbjct: 139 EELQNKLEDVVIDRN--LLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDN-SS 195
Query: 207 ERNGTLYEDFKNELEIMKSLQHINIVEILGYAWD---QG-PEVLIVMEYLEEGSLNYYLK 374
+R E+F +E MK H N++ +LG + QG P+ ++++ +++ G L+ YL
Sbjct: 196 QRE---IEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLL 252
Query: 375 FQ----GEK-LRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGL 539
+ G K + + LLK+ DIA GM+++S +N +HRDLA RN ++ + V ++DFGL
Sbjct: 253 YSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGL 312
Query: 540 ARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
++ I + YR +P+ W A ES + +++KSDVW++GVT WEI TR P
Sbjct: 313 SKKI-YSGDYYRQGRIAKMPVKWIAIESLADR-VYTSKSDVWAFGVTMWEIATRGMTPYP 370
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 87 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 134
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 135 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 192
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 193 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 250
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 251 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 282
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 669
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 670 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 789 PE-AIAFRKFTSASDAWSYGIVMWEVMS 815
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 272 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 319
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 320 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 377
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 378 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 435
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 436 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 467
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 669
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 670 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 789 PE-AIAFRKFTSASDAWSYGIVMWEVMS 815
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 272 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 319
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 320 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 377
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 378 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 435
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 436 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 467
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 272 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 319
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 320 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 377
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 378 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 435
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 436 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 467
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 473 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 527
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 528 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 586
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 587 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 646
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 647 PE-AIAFRKFTSASDAWSYGIVMWEVMS 673
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 669
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 670 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 789 PE-AIAFRKFTSASDAWSYGIVMWEVMS 815
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 669
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 670 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 789 PE-AIAFRKFTSASDAWSYGIVMWEVMS 815
>AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 272 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 319
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 320 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 377
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 378 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 435
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 436 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 467
>AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 124 bits (298), Expect = 6e-28
Identities = 84/213 (39%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLY-EDFKNELEIMKS 263
L K+G G +G V WM N + VAIK L + GT+ E F E ++MK
Sbjct: 278 LEVKLGQGCFGEV---WMGTWNGTTR---VAIKTL------KPGTMSPEAFLQEAQVMKK 325
Query: 264 LQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQ-GEKLRISHLLKYCKDIATGM 440
L+H +V++ YA + IV EY+ +GSL +LK + G+ LR+ L+ IA+GM
Sbjct: 326 LRHEKLVQL--YAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGM 383
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPE 620
+V N VHRDL NILV K++DFGLAR+I E+N Y + PI W APE
Sbjct: 384 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQGAKFPIKWTAPE 441
Query: 621 SAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
+A+ F+ KSDVWS+G+ E+ T+ R P
Sbjct: 442 AALY-GRFTIKSDVWSFGILLTELTTKGRVPYP 473
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 669
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 670 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 789 PE-AIAFRKFTSASDAWSYGIVMWEVMS 815
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 124 bits (298), Expect = 6e-28
Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 2/208 (0%)
Frame = +3
Query: 81 VTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMK 260
V + + IG+G +G V +G ++ ++ VAIK L +ER +F +E IM
Sbjct: 614 VKIEEVIGAGEFGEVCRGRLKAPGKKESC--VAIKTLKGGYTERQR---REFLSEASIMG 668
Query: 261 SLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGM 440
+H NI+ + G + P V+I+ E++E G+L+ +L+ + + L+ + IA+GM
Sbjct: 669 QFEHPNIIRLEGVVTNSMP-VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 727
Query: 441 DHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEEN--TYRLKTERLLPINWYA 614
+++ + VHRDLA RNILV + K+SDFGL+R + + + TY +PI W A
Sbjct: 728 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 787
Query: 615 PESAVEPWHFSTKSDVWSYGVTAWEIFT 698
PE A+ F++ SD WSYG+ WE+ +
Sbjct: 788 PE-AIAFRKFTSASDAWSYGIVMWEVMS 814
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 123 bits (297), Expect = 8e-28
Identities = 83/212 (39%), Positives = 112/212 (52%), Gaps = 1/212 (0%)
Frame = +3
Query: 87 LTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSL 266
L +++G+G +G GW + +VA+K L +Q S G L E +MK L
Sbjct: 248 LVERLGAGQFGRC--GW----GTTTGTTKVAVKSL-KQGSMSAGRL----PAEANLMKQL 296
Query: 267 QHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKF-QGEKLRISHLLKYCKDIATGMD 443
QH +V + YA + I+ EY+E GSL +LK G KL I+ LL IA GM
Sbjct: 297 QHQRLVRL--YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 354
Query: 444 HVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPES 623
+ +N +HRDL NILV + KI+DFGLAR+I E+N Y + PI W APE
Sbjct: 355 FIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREGAKFPIKWTAPE- 411
Query: 624 AVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
A+ F+ KSDVWS+G+ EI T R P
Sbjct: 412 AINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 443
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 123 bits (297), Expect = 8e-28
Identities = 75/216 (34%), Positives = 114/216 (52%), Gaps = 1/216 (0%)
Frame = +3
Query: 102 GSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHINI 281
G G YG V++G ++ + VA+K L E E+F E +MK ++H N+
Sbjct: 68 GGGQYGEVYEGVWKK-----YSLTVAVKTLKEDTME-----VEEFLKEAAVMKEIKHPNL 117
Query: 282 VEILGYAWDQGPEVLIVMEYLEEGSLNYYLK-FQGEKLRISHLLKYCKDIATGMDHVSAK 458
V++LG + P I+ E++ G+L YL+ +++ LL I++ M+++ K
Sbjct: 118 VQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKK 176
Query: 459 NVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPW 638
N +HRDLA RN LV + VK++DFGL+R++ + TY PI W APES
Sbjct: 177 NFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD--TYTAHAGAKFPIKWTAPESLAYN- 233
Query: 639 HFSTKSDVWSYGVTAWEIFTRARQEVPKFDVERPRE 746
FS KSDVW++GV WEI T P D+ + E
Sbjct: 234 KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE 269
>U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein.
Length = 999
Score = 123 bits (296), Expect = 1e-27
Identities = 81/240 (33%), Positives = 134/240 (55%), Gaps = 9/240 (3%)
Frame = +3
Query: 27 EFLKISLESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQAS 206
E L+ LE +V L+ L K +G G +G V +G +++++ S + V KL +S
Sbjct: 571 EELQNKLEDVVIDRN--LLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDN-SS 627
Query: 207 ERNGTLYEDFKNELEIMKSLQHINIVEILGYAWD---QG-PEVLIVMEYLEEGSLNYYLK 374
R E+F +E MK H N++ +LG + QG P+ ++++ +++ G L+ YL
Sbjct: 628 HRE---IEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLL 684
Query: 375 FQ----GEK-LRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGL 539
+ G K + + LLK+ DIA GM+++S +N +HRDLA RN ++ + V ++DFGL
Sbjct: 685 YSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGL 744
Query: 540 ARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVP 719
++ I + YR +P+ W A ES + +++KSDVW++GVT WEI TR P
Sbjct: 745 SKKI-YSGDYYRQGRIAKMPVKWIAIESLADR-VYTSKSDVWAFGVTMWEIRTRGMTPYP 802
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,376,021
Number of Sequences: 237096
Number of extensions: 2258141
Number of successful extensions: 11559
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7323
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8191
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12547615372
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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