Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP20_F_B21
(920 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 126 1e-28
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 126 1e-28
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 126 1e-28
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 126 1e-28
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 126 1e-28
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 126 1e-28
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 126 1e-28
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 126 1e-28
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 126 1e-28
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 126 1e-28
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 126 1e-28
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 126 1e-28
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 126 1e-28
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 117 5e-26
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 117 5e-26
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 112 1e-24
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 112 1e-24
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 112 1e-24
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 112 1e-24
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 112 1e-24
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 112 1e-24
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 112 1e-24
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 111 3e-24
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 111 5e-24
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 79 2e-14
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 67 7e-11
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 64 9e-10
AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein ... 50 1e-05
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 58 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 117
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 118 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 177
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 178 HMYAKNFYGGNGIVGAQVPLGAGIA 202
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 172 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 231
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 232 YNMAALWKL 240
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 72 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 131
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 132 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 191
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 192 HMYAKNFYGGNGIVGAQVPLGAGIA 216
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 186 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 245
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 246 YNMAALWKL 254
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 126 bits (303), Expect = 1e-28
Identities = 64/145 (44%), Positives = 82/145 (56%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQVPLG +A
Sbjct: 154 HMYAKNFYGGNGIVGAQVPLGAGIA 178
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 148 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 207
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 208 YNMAALWKL 216
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 117 bits (282), Expect = 5e-26
Identities = 64/152 (42%), Positives = 83/152 (54%), Gaps = 7/152 (4%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXS-------VITAYRCHGWTYLMGVSVLXVLSELTGRRTGCS 681
GQ + +ITAYR HG+T+ G+SV +L+ELTGR+ GC+
Sbjct: 94 CDGQFLLPLTQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCA 153
Query: 682 RGKEGPCICTDATSMVATGIVGAQVPLGXXLA 777
+GK G GIVGAQVPLG +A
Sbjct: 154 KGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIA 185
Score = 51.2 bits (117), Expect = 5e-06
Identities = 23/50 (46%), Positives = 27/50 (54%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDG 833
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG
Sbjct: 155 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG 204
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 117 bits (282), Expect = 5e-26
Identities = 60/138 (43%), Positives = 77/138 (55%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 94 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSM 153
Query: 703 ICTDATSMVATGIVGAQV 756
GIVGAQV
Sbjct: 154 HMYAKNFYGGNGIVGAQV 171
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 51 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 110
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 111 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 170
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 171 HMYTKNFYGGNGIVGAQGPLGAGIA 195
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 165 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 224
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 225 FNMAALWKL 233
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 112 bits (270), Expect = 1e-24
Identities = 60/145 (41%), Positives = 76/145 (52%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G+SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 111 bits (267), Expect = 3e-24
Identities = 60/145 (41%), Positives = 75/145 (51%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI L+ + P + L + LK Y + +RR+E + LYK+K IRGFCHL
Sbjct: 32 ATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHL 91
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEGPC 702
GQ VIT+YR HG Y G SV +L+ELTGRR GC++GK G
Sbjct: 92 CDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGCAKGKGGSM 151
Query: 703 ICTDATSMVATGIVGAQVPLGXXLA 777
GIVGAQ PLG +A
Sbjct: 152 HMYTKNFYGGNGIVGAQGPLGAGIA 176
Score = 78.6 bits (185), Expect = 3e-14
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG GP+G I A Y+ + LYGDG AN GQ EA
Sbjct: 146 GKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEA 205
Query: 864 YNMSKLWGL 890
+NM+ LW L
Sbjct: 206 FNMAALWKL 214
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 111 bits (266), Expect = 5e-24
Identities = 53/118 (44%), Positives = 70/118 (59%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 72 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 131
Query: 523 YSGQXXXXXXXXXXXXXXXSVITAYRCHGWTYLMGVSVLXVLSELTGRRTGCSRGKEG 696
GQ +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GK G
Sbjct: 132 CDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGG 189
Score = 37.1 bits (82), Expect = 0.090
Identities = 13/18 (72%), Positives = 16/18 (88%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNG 737
G+G SMH+Y +NFYGGNG
Sbjct: 186 GKGGSMHMYAKNFYGGNG 203
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 79.0 bits (186), Expect = 2e-14
Identities = 36/69 (52%), Positives = 41/69 (59%)
Frame = +3
Query: 684 GQGRSMHLYGRNFYGGNGNCWCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEA 863
G+G SMH+Y +NFYGGNG P+G I A Y LYGDG AN GQ FEA
Sbjct: 19 GKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEA 78
Query: 864 YNMSKLWGL 890
YNM+ LW L
Sbjct: 79 YNMAALWKL 87
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/49 (48%), Positives = 30/49 (61%)
Frame = +1
Query: 631 SVLXVLSELTGRRTGCSRGKEGPCICTDATSMVATGIVGAQVPLGXXLA 777
SV +L+ELTGR+ GC++GK G GIVGAQVPLG +A
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIA 49
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 67.3 bits (157), Expect = 7e-11
Identities = 31/64 (48%), Positives = 39/64 (60%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 34 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 93
Query: 523 YSGQ 534
GQ
Sbjct: 94 CDGQ 97
Score = 46.4 bits (105), Expect = 1e-04
Identities = 24/49 (48%), Positives = 25/49 (51%)
Frame = +3
Query: 744 WCAGPVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEAYNMSKLWGL 890
W AG I A Y LYGDG AN GQ FEAYNM+ LW L
Sbjct: 173 WAAG-----IALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKL 216
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 63.7 bits (148), Expect = 9e-10
Identities = 29/60 (48%), Positives = 37/60 (61%)
Frame = +1
Query: 343 ATFEIXPYKLHKWDXVPATSATLXSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 522
ATFEI LH+ + P + L ED LK Y + +RR+E + LYK+KIIRGFCHL
Sbjct: 62 ATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 121
>AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein
protein.
Length = 302
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/45 (51%), Positives = 25/45 (55%)
Frame = +3
Query: 756 PVGXRIGFAPXYRADGGXTFALYGDGXANXGQFFEAYNMSKLWGL 890
P+G I A Y LYGDG AN GQ FEAYNM+ LW L
Sbjct: 84 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKL 128
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,769,897
Number of Sequences: 237096
Number of extensions: 1832943
Number of successful extensions: 4245
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3845
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4188
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11992411152
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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