Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP18_F_O18
(1306 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 216 1e-55
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 215 2e-55
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 215 2e-55
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 215 2e-55
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 215 2e-55
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 215 2e-55
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 215 2e-55
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 215 2e-55
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 215 2e-55
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 215 2e-55
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 215 2e-55
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 215 2e-55
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 215 4e-55
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 214 7e-55
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 210 1e-53
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 199 2e-50
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 199 2e-50
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 199 2e-50
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 199 2e-50
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 199 2e-50
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 199 2e-50
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 199 2e-50
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 198 5e-50
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 197 6e-50
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 196 1e-49
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 196 1e-49
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 196 1e-49
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 196 1e-49
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 196 1e-49
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 196 1e-49
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 196 1e-49
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 196 1e-49
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 196 1e-49
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 196 1e-49
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 196 2e-49
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 196 2e-49
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 196 2e-49
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 196 2e-49
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 196 2e-49
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 196 2e-49
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 196 2e-49
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 196 2e-49
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 196 2e-49
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 196 2e-49
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 195 3e-49
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 195 3e-49
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 195 3e-49
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 195 3e-49
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 195 3e-49
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 195 3e-49
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 195 3e-49
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 194 4e-49
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 194 4e-49
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 193 1e-48
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 192 2e-48
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 192 2e-48
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 192 2e-48
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 192 2e-48
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 192 2e-48
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 191 4e-48
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 189 2e-47
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 188 4e-47
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 186 2e-46
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 180 8e-45
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 180 8e-45
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 180 8e-45
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 180 8e-45
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 180 8e-45
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 180 8e-45
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 180 8e-45
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 180 8e-45
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 180 8e-45
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 180 1e-44
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 180 1e-44
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 180 1e-44
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 173 1e-42
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 173 1e-42
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 173 1e-42
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 173 1e-42
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 153 3e-38
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 149 3e-35
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 149 3e-35
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 145 4e-34
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 145 4e-34
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 114 6e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 114 6e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 114 6e-25
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 110 1e-23
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 109 2e-23
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 109 3e-23
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 87 1e-16
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 3e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 42 0.004
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 34 1.3
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 34 1.3
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.3
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.3
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 34 1.3
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 34 1.3
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 32 4.0
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 32 4.0
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 216 bits (528), Expect = 1e-55
Identities = 105/229 (45%), Positives = 153/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P+ K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-CL-07
protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 215 bits (526), Expect = 2e-55
Identities = 105/229 (45%), Positives = 152/229 (66%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 122 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 181
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 182 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 229
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 215 bits (524), Expect = 4e-55
Identities = 104/227 (45%), Positives = 151/227 (66%), Gaps = 3/227 (1%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+ +
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 536 TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP-K 712
V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 713 ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVE 886
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ+E
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Query: 887 CHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
CHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 214 bits (522), Expect = 7e-55
Identities = 104/229 (45%), Positives = 151/229 (65%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P + G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D W ME+LV +GL K+IG+SNFN Q++ IL K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 210 bits (512), Expect = 1e-53
Identities = 104/229 (45%), Positives = 151/229 (65%), Gaps = 3/229 (1%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 529
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 530 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 709
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 710 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
S + S+ + +D ME+LV +GL K+IG+SNFN Q++ IL+K K KPAVNQ
Sbjct: 125 LDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 881 VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ECHPYLTQ++L ++C+ K I+++ + LGS P K + S+++DP
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 129
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 130 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 189
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 190 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 242
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 199 bits (486), Expect = 2e-50
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase homolog
protein.
Length = 323
Score = 198 bits (482), Expect = 5e-50
Identities = 103/233 (44%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 197 bits (481), Expect = 6e-50
Identities = 103/233 (44%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 200
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 201 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 253
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type 3
protein.
Length = 323
Score = 196 bits (479), Expect = 1e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 196 bits (477), Expect = 2e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 195 bits (476), Expect = 3e-49
Identities = 102/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWST HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase protein.
Length = 323
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 126 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 185
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 186 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 238
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase 4
protein.
Length = 323
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase 4
protein.
Length = 323
Score = 195 bits (475), Expect = 3e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase/bile
acid-binding protein protein.
Length = 323
Score = 194 bits (474), Expect = 4e-49
Identities = 101/233 (43%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ GY ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL++ K +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 194 bits (474), Expect = 4e-49
Identities = 100/233 (42%), Positives = 145/233 (62%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
+PK + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPYL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase homolog
protein.
Length = 323
Score = 193 bits (471), Expect = 1e-48
Identities = 100/233 (42%), Positives = 143/233 (61%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W ME GLAKSIGVSNFN ++ IL++ K +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like peptide
protein.
Length = 316
Score = 192 bits (469), Expect = 2e-48
Identities = 98/221 (44%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 192 bits (469), Expect = 2e-48
Identities = 98/221 (44%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 192 bits (469), Expect = 2e-48
Identities = 98/221 (44%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 192 bits (469), Expect = 2e-48
Identities = 98/221 (44%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase protein.
Length = 316
Score = 192 bits (469), Expect = 2e-48
Identities = 98/221 (44%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 191 bits (466), Expect = 4e-48
Identities = 98/233 (42%), Positives = 140/233 (60%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G A+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 701 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
P + + + D W ME GLAKSIGVSNFN Q++ IL+K K KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY + +L FC+ K+I+L + LGS+ N+ +++DP+
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase protein.
Length = 316
Score = 189 bits (460), Expect = 2e-47
Identities = 97/221 (43%), Positives = 135/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 733
LFI KLW TF LV A +L D L + D++LIH P K G+ PK
Sbjct: 73 LFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 734 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYLT 904
+ ++DAW ME+LV +GL K++GVSNF+ QI+K+L+K K KP NQVECHPYLT
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLT 192
Query: 905 QQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
Q++L ++C K I ++ + LGS P K + S+++DP
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWA-KPEDPSLLEDP 232
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase homolog
protein.
Length = 320
Score = 188 bits (458), Expect = 4e-47
Identities = 98/233 (42%), Positives = 142/233 (60%), Gaps = 6/233 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 520
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 521 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
KI DG+V+R+++F KLW HR +L A SL +L L++ DL+LIH P+S+K G
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 701 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPA 871
IPK + I + D W +E LAKSIGVSNFN + ++ IL+K +VKP
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPV 184
Query: 872 VNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 185 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPV 237
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 186 bits (453), Expect = 2e-46
Identities = 96/225 (42%), Positives = 139/225 (61%), Gaps = 6/225 (2%)
Frame = +2
Query: 374 MPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVR 544
MPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++KI DG+V+
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 545 RDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISS 721
R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G + +PK +
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENG 120
Query: 722 VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHP 895
+ + D W ME GLAKSIGVSNFN Q++ IL+K K KP NQVECHP
Sbjct: 121 KVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHP 180
Query: 896 YLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
YL Q +L FC+ K+I+L LG++ N+ +++DP+
Sbjct: 181 YLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 225
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 180 bits (439), Expect = 8e-45
Identities = 94/223 (42%), Positives = 135/223 (60%), Gaps = 6/223 (2%)
Frame = +2
Query: 380 VIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRD 550
V+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++KI DG+V+R+
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 551 ELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISSVI 727
++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G IPK + I
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 728 QYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQVECHPYL 901
+ D W +E GLAKSIGVSNFN Q++ IL+K K KP NQVECHPY
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 180
Query: 902 TQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 181 NQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 223
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 180 bits (439), Expect = 8e-45
Identities = 94/208 (45%), Positives = 126/208 (60%), Gaps = 2/208 (0%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQVEC 889
I Y Y + W +E LVAKGL +++G+SNFNS QI IL V+PAV QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 890 HPYLTQQRLHKFCEEKEIILSCFXVLGS 973
HPYL Q L C+ + + ++ + LGS
Sbjct: 188 HPYLAQNELIAHCQARGLEVTAYSPLGS 215
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 180 bits (437), Expect = 1e-44
Identities = 95/221 (42%), Positives = 133/221 (60%), Gaps = 22/221 (9%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 700
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 701 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 854 G--KVKPAVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLG 970
+ KP NQ+ECHPYLTQ+ L FC+ +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 180 bits (437), Expect = 1e-44
Identities = 95/221 (42%), Positives = 133/221 (60%), Gaps = 22/221 (9%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 700
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 701 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 854 G--KVKPAVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLG 970
+ KP NQ+ECHPYLTQ+ L FC+ +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 180 bits (437), Expect = 1e-44
Identities = 95/221 (42%), Positives = 133/221 (60%), Gaps = 22/221 (9%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 700
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 701 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 854 G--KVKPAVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLG 970
+ KP NQ+ECHPYLTQ+ L FC+ +++ ++ + LG
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 173 bits (421), Expect = 1e-42
Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 7/234 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 517
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 518 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 697
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 698 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 868
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 869 AVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY TQ +L KFC++ +I+++ + LG+ P ++ ++ D L
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDAL 243
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 173 bits (421), Expect = 1e-42
Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 7/234 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 517
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 518 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 697
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 698 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 868
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 869 AVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY TQ +L KFC++ +I+++ + LG+ P ++ ++ D L
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDAL 243
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 173 bits (421), Expect = 1e-42
Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 7/234 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 517
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 518 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 697
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 698 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 868
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 869 AVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY TQ +L KFC++ +I+++ + LG+ P ++ ++ D L
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDAL 243
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 173 bits (421), Expect = 1e-42
Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 7/234 (2%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 517
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 518 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 697
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 698 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKP 868
P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K K KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 869 AVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
NQVECHPY TQ +L KFC++ +I+++ + LG+ P ++ ++ D L
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDAL 243
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 153 bits (372), Expect(2) = 3e-38
Identities = 78/180 (43%), Positives = 110/180 (61%), Gaps = 3/180 (1%)
Frame = +2
Query: 500 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 679
+G AI++KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 86
Query: 680 SLKEGNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 856
S+K G IPK + I + D W +E GLAKSIGVSNFN Q++ IL+K
Sbjct: 87 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 146
Query: 857 --KVKPAVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDPL 1030
K KP NQVECHPY Q++L FC+ K+I+L + LGS N+ +++DP+
Sbjct: 147 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 206
Score = 26.2 bits (55), Expect(2) = 3e-38
Identities = 10/16 (62%), Positives = 12/16 (75%)
Frame = +2
Query: 350 LKLRDGTFMPVIALGT 397
+KL DG FMPV+ GT
Sbjct: 6 VKLNDGHFMPVLGFGT 21
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 149 bits (360), Expect = 3e-35
Identities = 89/241 (36%), Positives = 134/241 (55%), Gaps = 8/241 (3%)
Frame = +2
Query: 332 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 502
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 503 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 682
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 683 LKE-GNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 856
+K+ G +PK S I + D W +++ IL+K
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW-----------------------ELELILNKP 161
Query: 857 --KVKPAVNQ-VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ KP NQ VECHPYL Q +L +FC+ K+I+L + LGS+ P + ++++P
Sbjct: 162 GLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEP 221
Query: 1028 L 1030
+
Sbjct: 222 I 222
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 149 bits (360), Expect = 3e-35
Identities = 89/241 (36%), Positives = 134/241 (55%), Gaps = 8/241 (3%)
Frame = +2
Query: 332 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 502
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 503 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 682
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 683 LKE-GNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG 856
+K+ G +PK S I + D W +++ IL+K
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW-----------------------ELELILNKP 161
Query: 857 --KVKPAVNQ-VECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
+ KP NQ VECHPYL Q +L +FC+ K+I+L + LGS+ P + ++++P
Sbjct: 162 GLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEP 221
Query: 1028 L 1030
+
Sbjct: 222 I 222
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 145 bits (351), Expect = 4e-34
Identities = 82/192 (42%), Positives = 112/192 (58%), Gaps = 22/192 (11%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 700
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 701 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 854 G--KVKPAVNQV 883
+ KP NQ+
Sbjct: 184 PGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 145 bits (351), Expect = 4e-34
Identities = 82/192 (42%), Positives = 112/192 (58%), Gaps = 22/192 (11%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 700
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 701 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q++++L+K
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 854 G--KVKPAVNQV 883
+ KP NQ+
Sbjct: 184 PGLRFKPLTNQI 195
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 6e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 332 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 502
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 503 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 682
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 683 LK 688
+K
Sbjct: 125 MK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 6e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 332 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 502
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 503 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 682
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 683 LK 688
+K
Sbjct: 125 MK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 114 bits (275), Expect = 6e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 332 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 502
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 503 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 682
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 683 LK 688
+K
Sbjct: 125 MK 126
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 110 bits (264), Expect = 1e-23
Identities = 59/137 (43%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Frame = +2
Query: 356 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 535
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 536 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 712
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 713 -ISSVIQYSEFDYMDAW 760
I Y Y + W
Sbjct: 128 NADGTICYDSTHYKETW 144
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 109 bits (263), Expect = 2e-23
Identities = 54/127 (42%), Positives = 81/127 (63%), Gaps = 3/127 (2%)
Frame = +2
Query: 329 SVKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKL 499
S + ++KL DG FMP++ GT++ + E V+ AID+GYR ID+AY + NE+
Sbjct: 2 SFNRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 500 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 679
IG+AI+ KI +GTV+R ++F K+W TF R +LV+ +SL L L + DL+L H P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 680 SLKEGNS 700
L+ G S
Sbjct: 122 PLQPGRS 128
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 109 bits (261), Expect = 3e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +2
Query: 374 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 553
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 554 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 688
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens cDNA
FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 87.0 bits (206), Expect = 1e-16
Identities = 45/121 (37%), Positives = 70/121 (57%), Gaps = 3/121 (2%)
Frame = +2
Query: 677 MSLKEGNSSIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDK 853
M+ K G+ P+ + Y + + W ME GL KS+GVSNFN Q++ IL+K
Sbjct: 1 MAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 60
Query: 854 G--KVKPAVNQVECHPYLTQQRLHKFCEEKEIILSCFXVLGSKGTPTEYKSNNXSVIDDP 1027
K KP NQVECHPY TQ +L KFC++ +I+++ + LG+ P + + +++D P
Sbjct: 61 PGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWRQLHKLALLDLP 120
Query: 1028 L 1030
+
Sbjct: 121 I 121
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.0 bits (104), Expect = 3e-04
Identities = 25/48 (52%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +2
Query: 743 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKG--KVKPAVNQ 880
D W ME GLAKSIGVSNFN Q++ IL+K K KP NQ
Sbjct: 20 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 42.3 bits (95), Expect = 0.004
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +2
Query: 572 LWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 700
+W TF R +LV+ +SL L L + DL+L H P+ L+ G S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/59 (30%), Positives = 29/59 (49%)
Frame = +2
Query: 707 PKISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIQKILDKGKVKPAVNQV 883
P I + S W +E+LV +IG S+ + TQ++++ +VKP NQV
Sbjct: 130 PPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein
protein.
Length = 671
Score = 32.3 bits (70), Expect = 4.0
Identities = 13/25 (52%), Positives = 14/25 (56%)
Frame = +3
Query: 1062 PPXPXGXQIPNPXRSYXXXKXPPGP 1136
PP P G Q+P P SY K P GP
Sbjct: 342 PPPPPGTQLPPPPPSYPSPKPPVGP 366
>AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein.
Length = 671
Score = 32.3 bits (70), Expect = 4.0
Identities = 13/25 (52%), Positives = 14/25 (56%)
Frame = +3
Query: 1062 PPXPXGXQIPNPXRSYXXXKXPPGP 1136
PP P G Q+P P SY K P GP
Sbjct: 342 PPPPPGTQLPPPPPSYPSPKPPVGP 366
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 170,453,585
Number of Sequences: 237096
Number of extensions: 3880668
Number of successful extensions: 14473
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 13180
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14244
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 18825810660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -