Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP18_F_L14
(1230 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 325 2e-88
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 323 7e-88
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 318 2e-86
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 318 2e-86
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 318 2e-86
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 318 2e-86
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 318 2e-86
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 318 2e-86
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 318 2e-86
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 318 2e-86
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 313 7e-85
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 313 7e-85
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 311 4e-84
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 311 4e-84
AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein. 49 4e-05
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 325 bits (799), Expect = 2e-88
Identities = 148/236 (62%), Positives = 183/236 (77%)
Frame = +3
Query: 147 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 326
G D ++P LNKGMAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+KYI
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109
Query: 327 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 506
LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+
Sbjct: 110 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLA 169
Query: 507 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 686
+L +WPE +++A+VVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +D
Sbjct: 170 TMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229
Query: 687 VGTNTQSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGNA 854
VGTN + +L DPLYIGL+ +RV G YD+L DEFM+AV ++G NCL+ FEDF NA
Sbjct: 230 VGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANA 285
Score = 39.5 bits (88), Expect = 0.024
Identities = 17/22 (77%), Positives = 18/22 (81%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRNKY FND+I GT
Sbjct: 287 AFRLLNKYRNKYCMFNDDIQGT 308
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 323 bits (794), Expect = 7e-88
Identities = 148/236 (62%), Positives = 182/236 (77%)
Frame = +3
Query: 147 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 326
G D ++P LNKGMAFT+EER LGIHGL+PP Q+ Q+ +R ++ L+KYI
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLGQDVQLLRIMGYYERQQSDLDKYII 109
Query: 327 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 506
LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+
Sbjct: 110 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLA 169
Query: 507 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 686
+L +WPE +++A+VVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +D
Sbjct: 170 TMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229
Query: 687 VGTNTQSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGNA 854
VGTN + +L DPLYIGL+ +RV G YD+L DEFM+AV ++G NCL+ FEDF NA
Sbjct: 230 VGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANA 285
Score = 39.5 bits (88), Expect = 0.024
Identities = 17/22 (77%), Positives = 18/22 (81%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRNKY FND+I GT
Sbjct: 287 AFRLLNKYRNKYCMFNDDIQGT 308
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 13 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 72
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 73 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 132
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 133 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 192
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 193 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 242
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 245 AFRLLNKYRNQYCTFNDDIQGT 266
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 40.3 bits (90), Expect = 0.014
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y TFND+I GT
Sbjct: 252 AFRLLNKYRNQYCTFNDDIQGT 273
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 318 bits (782), Expect = 2e-86
Identities = 143/230 (62%), Positives = 176/230 (76%)
Frame = +3
Query: 162 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 341
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 342 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 521
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 522 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNT 701
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 702 QSMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
+ +L DPLYIGLRQRRVRG +YD+ DEFM AV +YG NCL+ FEDF N
Sbjct: 200 EELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFAN 249
Score = 37.1 bits (82), Expect = 0.13
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFRLL KYRN+Y T ND+I GT
Sbjct: 252 AFRLLNKYRNQYCTSNDDIQGT 273
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 313 bits (769), Expect = 7e-85
Identities = 136/229 (59%), Positives = 180/229 (78%)
Frame = +3
Query: 165 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 344
+P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 345 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 524
RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NW
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNW 150
Query: 525 PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQ 704
PE V+A+VVTDGERILGLGDLG GMGIPVGKL LYTA GI+P +CLP+ IDVGT+
Sbjct: 151 PENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNI 210
Query: 705 SMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
++L DP Y+GL Q+R R YD+L DEFM+A+ RYG+N L+ FEDFGN
Sbjct: 211 ALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGN 259
Score = 37.9 bits (84), Expect = 0.075
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFR L KYR KY TFND+I GT
Sbjct: 262 AFRFLRKYREKYCTFNDDIQGT 283
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 313 bits (769), Expect = 7e-85
Identities = 136/229 (59%), Positives = 180/229 (78%)
Frame = +3
Query: 165 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 344
+P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 345 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 524
RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NW
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNW 150
Query: 525 PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQ 704
PE V+A+VVTDGERILGLGDLG GMGIPVGKL LYTA GI+P +CLP+ IDVGT+
Sbjct: 151 PENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNI 210
Query: 705 SMLDDPLYIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGN 851
++L DP Y+GL Q+R R YD+L DEFM+A+ RYG+N L+ FEDFGN
Sbjct: 211 ALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGN 259
Score = 37.9 bits (84), Expect = 0.075
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNIXGT 922
AFR L KYR KY TFND+I GT
Sbjct: 262 AFRFLRKYREKYCTFNDDIQGT 283
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 311 bits (763), Expect = 4e-84
Identities = 141/223 (63%), Positives = 174/223 (78%)
Frame = +3
Query: 186 MAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 365
MAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LFY
Sbjct: 1 MAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFY 60
Query: 366 RFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRA 545
R + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A
Sbjct: 61 RVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKA 120
Query: 546 IVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPL 725
+VVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +DVGTN + +L DPL
Sbjct: 121 VVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPL 180
Query: 726 YIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGNA 854
YIGL+ +RV G YD+L DEFM+AV ++G NCL+ FEDF NA
Sbjct: 181 YIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANA 223
Score = 35.5 bits (78), Expect = 0.40
Identities = 15/19 (78%), Positives = 16/19 (84%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNI 913
AFRLL KYRNKY FND+I
Sbjct: 225 AFRLLNKYRNKYCMFNDDI 243
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 311 bits (763), Expect = 4e-84
Identities = 141/223 (63%), Positives = 174/223 (78%)
Frame = +3
Query: 186 MAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFY 365
MAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+KYI LM L DRNE LFY
Sbjct: 1 MAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFY 60
Query: 366 RFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRA 545
R + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+ +L +WPE +++A
Sbjct: 61 RVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKA 120
Query: 546 IVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPL 725
+VVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +DVGTN + +L DPL
Sbjct: 121 VVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPL 180
Query: 726 YIGLRQRRVRGPDYDELXDEFMRAVVRRYGQNCLVXFEDFGNA 854
YIGL+ +RV G YD+L DEFM+AV ++G NCL+ FEDF NA
Sbjct: 181 YIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANA 223
Score = 35.5 bits (78), Expect = 0.40
Identities = 15/19 (78%), Positives = 16/19 (84%)
Frame = +2
Query: 857 AFRLLXKYRNKYXTFNDNI 913
AFRLL KYRNKY FND+I
Sbjct: 225 AFRLLNKYRNKYCMFNDDI 243
>AB045122-1|BAB40980.1| 44|Homo sapiens ME2 protein.
Length = 44
Score = 48.8 bits (111), Expect = 4e-05
Identities = 20/43 (46%), Positives = 32/43 (74%)
Frame = +3
Query: 183 GMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 311
GMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL
Sbjct: 1 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPL 43
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 141,551,682
Number of Sequences: 237096
Number of extensions: 3316991
Number of successful extensions: 8173
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 7512
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8169
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17449654910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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