Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP18_F_B01
(1218 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC020590-1|AAH20590.1| 265|Homo sapiens anterior pharynx defect... 192 3e-48
BC015568-1|AAH15568.1| 265|Homo sapiens anterior pharynx defect... 192 3e-48
BC001230-1|AAH01230.1| 265|Homo sapiens anterior pharynx defect... 192 3e-48
AY113699-1|AAM61956.1| 265|Homo sapiens presenilin stabilizatio... 192 3e-48
AL138795-6|CAI22811.1| 265|Homo sapiens anterior pharynx defect... 192 3e-48
AF508787-1|AAN63816.1| 251|Homo sapiens presenilin stabilizatio... 192 3e-48
AF151835-1|AAD34072.1| 251|Homo sapiens CGI-78 protein protein. 192 3e-48
BC017699-1|AAH17699.1| 247|Homo sapiens anterior pharynx defect... 190 7e-48
BC009501-1|AAH09501.1| 247|Homo sapiens anterior pharynx defect... 190 7e-48
BC008732-1|AAH08732.1| 247|Homo sapiens anterior pharynx defect... 190 7e-48
AY358951-1|AAQ89310.1| 247|Homo sapiens GAAV579 protein. 190 7e-48
AY113698-1|AAM61955.1| 247|Homo sapiens presenilin stabilizatio... 190 7e-48
AL138795-8|CAI22812.1| 247|Homo sapiens anterior pharynx defect... 190 7e-48
AK075295-1|BAC11529.1| 247|Homo sapiens protein ( Homo sapiens ... 190 7e-48
BC020905-1|AAH20905.1| 257|Homo sapiens anterior pharynx defect... 190 9e-48
AF508794-1|AAN63817.1| 257|Homo sapiens presenilin stabilizatio... 188 3e-47
AY358698-1|AAQ89061.1| 257|Homo sapiens TAAV688 protein. 188 5e-47
AL138795-7|CAI22813.1| 150|Homo sapiens anterior pharynx defect... 109 2e-23
AB189172-1|BAD95573.1| 216|Homo sapiens anterior pharynx defect... 83 1e-15
AB197122-1|BAE02660.1| 81|Homo sapiens anterior pharynx defect... 47 2e-04
AC005542-2|AAC32904.1| 461|Homo sapiens KIAA0589, partial CDS p... 33 2.8
AB011161-1|BAA25515.1| 687|Homo sapiens KIAA0589 protein protein. 33 2.8
>BC020590-1|AAH20590.1| 265|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 265
Score = 192 bits (467), Expect = 3e-48
Identities = 98/248 (39%), Positives = 149/248 (60%), Gaps = 9/248 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSAR 932
+S R
Sbjct: 239 IQRSLLCR 246
>BC015568-1|AAH15568.1| 265|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 265
Score = 192 bits (467), Expect = 3e-48
Identities = 98/248 (39%), Positives = 149/248 (60%), Gaps = 9/248 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSAR 932
+S R
Sbjct: 239 IQRSLLCR 246
>BC001230-1|AAH01230.1| 265|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 265
Score = 192 bits (467), Expect = 3e-48
Identities = 98/248 (39%), Positives = 149/248 (60%), Gaps = 9/248 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSIRS 238
Query: 909 FIQSFSAR 932
+S R
Sbjct: 239 IQRSLLCR 246
>AY113699-1|AAM61956.1| 265|Homo sapiens presenilin stabilization
factor b protein.
Length = 265
Score = 192 bits (467), Expect = 3e-48
Identities = 98/248 (39%), Positives = 149/248 (60%), Gaps = 9/248 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSAR 932
+S R
Sbjct: 239 IQRSLLCR 246
>AL138795-6|CAI22811.1| 265|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 265
Score = 192 bits (467), Expect = 3e-48
Identities = 98/248 (39%), Positives = 149/248 (60%), Gaps = 9/248 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSAR 932
+S R
Sbjct: 239 IQRSLLCR 246
>AF508787-1|AAN63816.1| 251|Homo sapiens presenilin stabilization
factor protein.
Length = 251
Score = 192 bits (467), Expect = 3e-48
Identities = 98/249 (39%), Positives = 150/249 (60%), Gaps = 9/249 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSARS 935
+S R+
Sbjct: 239 IQRSSCVRT 247
>AF151835-1|AAD34072.1| 251|Homo sapiens CGI-78 protein protein.
Length = 251
Score = 192 bits (467), Expect = 3e-48
Identities = 98/249 (39%), Positives = 150/249 (60%), Gaps = 9/249 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQSFSARS 935
+S R+
Sbjct: 239 IQRSSCVRT 247
>BC017699-1|AAH17699.1| 247|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>BC009501-1|AAH09501.1| 247|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>BC008732-1|AAH08732.1| 247|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>AY358951-1|AAQ89310.1| 247|Homo sapiens GAAV579 protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>AY113698-1|AAM61955.1| 247|Homo sapiens presenilin stabilization
factor a protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>AL138795-8|CAI22812.1| 247|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>AK075295-1|BAC11529.1| 247|Homo sapiens protein ( Homo sapiens
cDNA FLJ90814 fis, clone Y79AA1001013, highly similar to
Gamma-secretase subunit APH-1A. ).
Length = 247
Score = 190 bits (464), Expect = 7e-48
Identities = 97/244 (39%), Positives = 148/244 (60%), Gaps = 9/244 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYAVVPL- 392
M A FF C+ +AFG +F +TVA DP+R+II++A AF W VW+ +V +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 393 -RS-------YLVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
RS L+FG +++ QE+FR+ Y LL+K + GL +SE+ + +MAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGL FG +SG F+++N+LAD++GPG +G+ G + Y+F+TS+ +T +ILL+TFW ++FF
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
+ + Y + V+ SH S L+ LN Y AS+LP Y V + AF AGGS ++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLN--PWYEASLLPIYAVTVSMGLWAFITAGGSLRS 238
Query: 909 FIQS 920
+S
Sbjct: 239 IQRS 242
>BC020905-1|AAH20905.1| 257|Homo sapiens anterior pharynx defective
1 homolog B (C. elegans) protein.
Length = 257
Score = 190 bits (463), Expect = 9e-48
Identities = 97/240 (40%), Positives = 148/240 (61%), Gaps = 9/240 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYA--VV- 386
MT A FF C+ +AFG + ++ T+AT+P+RII +IA AF W VW+ V+
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 387 -----PLRSYL-VFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
P + YL +FG ++ QE+FR+ Y LL+K GLK I+ S +L +AYV
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRL-LAYV 119
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGLGFG MSG F+ VN L+DS+GPGT+G+ G + FF+ S+ MTL +ILL+ FW I+FF
Sbjct: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
G ++K + +L V+++H VS + ++S Y ++ ++ +L++ AF AGGS ++
Sbjct: 180 GCEKKKWGILLIVLLTHLLVSAQTFISS--YYGINLASAFIILVLMGTWAFLAAGGSCRS 237
>AF508794-1|AAN63817.1| 257|Homo sapiens presenilin stabilization
factor-like protein protein.
Length = 257
Score = 188 bits (459), Expect = 3e-47
Identities = 96/240 (40%), Positives = 148/240 (61%), Gaps = 9/240 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYA--VV- 386
MT A FF C+ +AFG + ++ T+AT+P+RII +IA AF W VW+ V+
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 387 -----PLRSYL-VFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
P + YL +FG ++ +E+FR+ Y LL+K GLK I+ S +L +AYV
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIREMFRFAYYKLLKKASEGLKSINPGETAPSMRL-LAYV 119
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGLGFG MSG F+ VN L+DS+GPGT+G+ G + FF+ S+ MTL +ILL+ FW I+FF
Sbjct: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
G ++K + +L V+++H VS + ++S Y ++ ++ +L++ AF AGGS ++
Sbjct: 180 GCEKKKWGILLIVLLTHLLVSAQTFISS--YYGINLASAFIILVLMGTWAFLAAGGSCRS 237
>AY358698-1|AAQ89061.1| 257|Homo sapiens TAAV688 protein.
Length = 257
Score = 188 bits (457), Expect = 5e-47
Identities = 96/240 (40%), Positives = 147/240 (61%), Gaps = 9/240 (3%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWYA--VV- 386
MT A FF C+ +AFG + ++ T+A +P+RII +IA AF W VW+ V+
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIAIEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 387 -----PLRSYL-VFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAYV 548
P + YL +FG ++ QE+FR+ Y LL+K GLK I+ S +L +AYV
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRL-LAYV 119
Query: 549 SGLGFGTMSGAFALVNVLADSIGPGTLGLSGGTEYFFVTSSAMTLCMILLNTFWSIIFFS 728
SGLGFG MSG F+ VN L+DS+GPGT+G+ G + FF+ S+ MTL +ILL+ FW I+FF
Sbjct: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
Query: 729 GFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXVLMITSYIAFRCAGGSXKT 908
G ++K + +L V+++H VS + ++S Y ++ ++ +L++ AF AGGS ++
Sbjct: 180 GCEKKKWGILLIVLLTHLLVSAQTFISS--YYGINLASAFIILVLMGTWAFLAAGGSCRS 237
>AL138795-7|CAI22813.1| 150|Homo sapiens anterior pharynx defective
1 homolog A (C. elegans) protein.
Length = 150
Score = 109 bits (262), Expect = 2e-23
Identities = 48/116 (41%), Positives = 77/116 (66%)
Frame = +3
Query: 462 LLLRKTEAGLKEISENHEIGSNKLEMAYVSGLGFGTMSGAFALVNVLADSIGPGTLGLSG 641
L+ K + GL +SE+ + +MAYVSGL FG +SG F+++N+LAD++GPG +G+ G
Sbjct: 35 LVAGKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHG 94
Query: 642 GTEYFFVTSSAMTLCMILLNTFWSIIFFSGFDEKNYLKILWVIISHFFVSFLSLLN 809
+ Y+F+TS+ +T +ILL+TFW ++FF + + Y + V+ SH S L+ LN
Sbjct: 95 DSPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGLTFLN 150
Score = 44.0 bits (99), Expect = 0.001
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIA 326
M A FF C+ +AFG +F +TVA DP+R+II++A
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVA 37
>AB189172-1|BAD95573.1| 216|Homo sapiens anterior pharynx defective
1b short splicing variant protein.
Length = 216
Score = 83.4 bits (197), Expect = 1e-15
Identities = 45/119 (37%), Positives = 66/119 (55%), Gaps = 9/119 (7%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIAAAFGWXXXXXXXXXVWY--AVV- 386
MT A FF C+ +AFG + ++ T+AT+P+RII +IA AF W VW+ V+
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 387 -----PLRSY-LVFGMIFAIIFQELFRYGMYLLLRKTEAGLKEISENHEIGSNKLEMAY 545
P + Y L+FG ++ QE+FR+ Y LL+K GLK I+ S +L +AY
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRL-LAY 118
Score = 57.2 bits (132), Expect = 1e-07
Identities = 27/78 (34%), Positives = 49/78 (62%)
Frame = +3
Query: 675 MTLCMILLNTFWSIIFFSGFDEKNYLKILWVIISHFFVSFLSLLNSRELYAASILPSYXV 854
MTL +ILL+ FW I+FF G ++K + +L V+++H VS + ++S Y ++ ++ +
Sbjct: 121 MTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISS--YYGINLASAFII 178
Query: 855 LMITSYIAFRCAGGSXKT 908
L++ AF AGGS ++
Sbjct: 179 LVLMGTWAFLAAGGSCRS 196
>AB197122-1|BAE02660.1| 81|Homo sapiens anterior pharynx defective
1b splice variant-2 protein.
Length = 81
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/37 (48%), Positives = 27/37 (72%)
Frame = +3
Query: 216 MTLAEFFSCSLLAFGAPIVMFAMTVATDPVRIIIMIA 326
MT A FF C+ +AFG + ++ T+AT+P+RII +IA
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIA 37
>AC005542-2|AAC32904.1| 461|Homo sapiens KIAA0589, partial CDS
protein.
Length = 461
Score = 32.7 bits (71), Expect = 2.8
Identities = 16/54 (29%), Positives = 26/54 (48%)
Frame = -3
Query: 409 KTKYDLRGTTAYHTNEDNKKDSNHPNAAAIIMMMRTGSVATVIANITIGAPNAS 248
+ +YDLRG +Y T ED + P T S+AT +++ ++ P S
Sbjct: 279 EAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERS 332
>AB011161-1|BAA25515.1| 687|Homo sapiens KIAA0589 protein protein.
Length = 687
Score = 32.7 bits (71), Expect = 2.8
Identities = 16/54 (29%), Positives = 26/54 (48%)
Frame = -3
Query: 409 KTKYDLRGTTAYHTNEDNKKDSNHPNAAAIIMMMRTGSVATVIANITIGAPNAS 248
+ +YDLRG +Y T ED + P T S+AT +++ ++ P S
Sbjct: 505 EAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERS 558
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,712,074
Number of Sequences: 237096
Number of extensions: 2718957
Number of successful extensions: 9727
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9283
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9683
length of database: 76,859,062
effective HSP length: 92
effective length of database: 55,046,230
effective search space used: 17229469990
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -