Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP16_F_B21
(885 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein. 288 2e-77
BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein. 288 2e-77
AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein. 288 2e-77
AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein. 288 2e-77
AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein. 272 1e-72
AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein. 272 1e-72
AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein. 268 2e-71
BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein pr... 84 6e-16
BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein. 84 6e-16
AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein. 84 6e-16
AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein. 84 6e-16
AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein. 84 6e-16
AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein. 84 6e-16
BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein. 84 7e-16
AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein. 84 7e-16
AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein. 84 7e-16
AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein. 84 7e-16
AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein. 61 6e-09
AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein. 61 6e-09
BC038294-1|AAH38294.1| 303|Homo sapiens C10orf46 protein protein. 50 8e-06
AY743663-1|AAU89709.1| 306|Homo sapiens cullin protein. 50 8e-06
AJ544771-1|CAD67614.1| 369|Homo sapiens hypothetical protein pr... 50 8e-06
AL139407-1|CAH73727.1| 246|Homo sapiens chromosome 10 open read... 50 1e-05
AK097728-1|BAC05153.1| 246|Homo sapiens protein ( Homo sapiens ... 50 1e-05
U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein. 36 0.26
AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2 prot... 33 1.0
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 31 4.2
AF265555-1|AAF75772.1| 4829|Homo sapiens ubiquitin-conjugating B... 31 4.2
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 31 4.2
AY696296-1|AAT85804.1| 211|Homo sapiens fibroblast growth facto... 30 9.7
AB044277-1|BAB03633.1| 211|Homo sapiens FGF-20 protein. 30 9.7
AB030648-1|BAB03530.1| 211|Homo sapiens fibroblast growth facto... 30 9.7
>BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 288 bits (707), Expect = 2e-77
Identities = 134/152 (88%), Positives = 143/152 (94%)
Frame = +3
Query: 231 KMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLY 410
KMRIRAFPMTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LY
Sbjct: 15 KMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLY 74
Query: 411 TGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQN 590
TGL+EVVT+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN
Sbjct: 75 TGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQN 134
Query: 591 EVDNVYNLGLIIFRDQVVRYGCIRDHLRQTLL 686
V+NVYNLGLIIFRDQVVRYGCIRDHLRQTLL
Sbjct: 135 NVENVYNLGLIIFRDQVVRYGCIRDHLRQTLL 166
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 167 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 225
Query: 865 AENT 876
AEN+
Sbjct: 226 AENS 229
>BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 288 bits (707), Expect = 2e-77
Identities = 134/152 (88%), Positives = 143/152 (94%)
Frame = +3
Query: 231 KMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLY 410
KMRIRAFPMTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LY
Sbjct: 15 KMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLY 74
Query: 411 TGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQN 590
TGL+EVVT+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN
Sbjct: 75 TGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQN 134
Query: 591 EVDNVYNLGLIIFRDQVVRYGCIRDHLRQTLL 686
V+NVYNLGLIIFRDQVVRYGCIRDHLRQTLL
Sbjct: 135 NVENVYNLGLIIFRDQVVRYGCIRDHLRQTLL 166
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 167 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 225
Query: 865 AENT 876
AEN+
Sbjct: 226 AENS 229
>AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 288 bits (707), Expect = 2e-77
Identities = 134/152 (88%), Positives = 143/152 (94%)
Frame = +3
Query: 231 KMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLY 410
KMRIRAFPMTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LY
Sbjct: 15 KMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLY 74
Query: 411 TGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQN 590
TGL+EVVT+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN
Sbjct: 75 TGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQN 134
Query: 591 EVDNVYNLGLIIFRDQVVRYGCIRDHLRQTLL 686
V+NVYNLGLIIFRDQVVRYGCIRDHLRQTLL
Sbjct: 135 NVENVYNLGLIIFRDQVVRYGCIRDHLRQTLL 166
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 167 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 225
Query: 865 AENT 876
AEN+
Sbjct: 226 AENS 229
>AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein.
Length = 786
Score = 288 bits (707), Expect = 2e-77
Identities = 134/152 (88%), Positives = 143/152 (94%)
Frame = +3
Query: 231 KMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLY 410
KMRIRAFPMTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LY
Sbjct: 33 KMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLY 92
Query: 411 TGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQN 590
TGL+EVVT+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN
Sbjct: 93 TGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQN 152
Query: 591 EVDNVYNLGLIIFRDQVVRYGCIRDHLRQTLL 686
V+NVYNLGLIIFRDQVVRYGCIRDHLRQTLL
Sbjct: 153 NVENVYNLGLIIFRDQVVRYGCIRDHLRQTLL 184
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 185 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 243
Query: 865 AENT 876
AEN+
Sbjct: 244 AENS 247
>AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 272 bits (666), Expect = 1e-72
Identities = 126/144 (87%), Positives = 135/144 (93%)
Frame = +3
Query: 231 KMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLY 410
KMRIRAFPMTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LY
Sbjct: 15 KMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLY 74
Query: 411 TGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQN 590
TGL+EVVT+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN
Sbjct: 75 TGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQN 134
Query: 591 EVDNVYNLGLIIFRDQVVRYGCIR 662
V+NVYNLGLIIFRDQVVRYGCIR
Sbjct: 135 NVENVYNLGLIIFRDQVVRYGCIR 158
Score = 35.5 bits (78), Expect = 0.26
Identities = 17/32 (53%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
Frame = +1
Query: 784 RAVYEEDFEKPFLHQSSEFIDW-NLEVXAENT 876
R+VYEEDFE PFL S+EF + + AEN+
Sbjct: 198 RSVYEEDFEAPFLEMSAEFFQMESQKFLAENS 229
>AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein.
Length = 746
Score = 272 bits (666), Expect = 1e-72
Identities = 126/144 (87%), Positives = 135/144 (93%)
Frame = +3
Query: 255 MTMDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVT 434
MTMDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LYTGL+EVVT
Sbjct: 1 MTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVT 60
Query: 435 QHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNEVDNVYNL 614
+HL KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN V+NVYNL
Sbjct: 61 EHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNL 120
Query: 615 GLIIFRDQVVRYGCIRDHLRQTLL 686
GLIIFRDQVVRYGCIRDHLRQTLL
Sbjct: 121 GLIIFRDQVVRYGCIRDHLRQTLL 144
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 145 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 203
Query: 865 AENT 876
AEN+
Sbjct: 204 AENS 207
>AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein.
Length = 744
Score = 268 bits (656), Expect = 2e-71
Identities = 124/142 (87%), Positives = 133/142 (93%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
MDEKYV IW LLKNAIQEIQ+KNNSGLSFEELYRNAYTMVLHKHGE+LYTGL+EVVT+H
Sbjct: 1 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEH 60
Query: 441 LETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNEVDNVYNLGL 620
L KVREDVL+SL+N FLQTLN AW DHQT+MVMIRDILMYMDRV+VQQN V+NVYNLGL
Sbjct: 61 LINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGL 120
Query: 621 IIFRDQVVRYGCIRDHLRQTLL 686
IIFRDQVVRYGCIRDHLRQTLL
Sbjct: 121 IIFRDQVVRYGCIRDHLRQTLL 142
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +1
Query: 688 ELVARERRGEVVDRLAIPKRLSDAHGSRVSTSRAVYEEDFEKPFLHQSSEFIDW-NLEVX 864
+++ARER+GEVVDR AI + R+VYEEDFE PFL S+EF + +
Sbjct: 143 DMIARERKGEVVDRGAIRNACQMLMILGLE-GRSVYEEDFEAPFLEMSAEFFQMESQKFL 201
Query: 865 AENT 876
AEN+
Sbjct: 202 AENS 205
>BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein
protein.
Length = 895
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 190 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 249
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 250 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 307
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 308 DMGLELFRAHII 319
>BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 208 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 267
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 268 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 325
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 326 DMGLELFRAHII 337
>AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein.
Length = 895
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 190 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 249
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 250 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 307
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 308 DMGLELFRAHII 319
>AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 208 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 267
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 268 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 325
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 326 DMGLELFRAHII 337
>AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein.
Length = 782
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 75 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 134
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 135 MKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 192
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 193 DMGLELFRAHII 204
>AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein.
Length = 781
Score = 84.2 bits (199), Expect = 6e-16
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ E Y + W LK A++ IQ + + EELY+ + +K LY L+++ H
Sbjct: 76 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 135
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ ++ W +H M+MIR I +++DR +V QN + +++
Sbjct: 136 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 193
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 194 DMGLELFRAHII 205
>BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ + Y + W L A++ +Q + + EELY+ + HK LY L++ H
Sbjct: 54 LPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDH 113
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR +V QN + +++
Sbjct: 114 VQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIW 171
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 172 DMGLELFRTHII 183
>AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ + Y + W L A++ +Q + + EELY+ + HK LY L++ H
Sbjct: 54 LPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDH 113
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR +V QN + +++
Sbjct: 114 VQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIW 171
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 172 DMGLELFRTHII 183
>AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ + Y + W L A++ +Q + + EELY+ + HK LY L++ H
Sbjct: 54 LPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDH 113
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR +V QN + +++
Sbjct: 114 VQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIW 171
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 172 DMGLELFRTHII 183
>AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein.
Length = 759
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAYTMVLHKHGERLYTGLKEVVTQH 440
+ + Y + W L A++ +Q + + EELY+ + HK LY L++ H
Sbjct: 54 LPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDH 113
Query: 441 LETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQQNE-VDNVY 608
++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR +V QN + +++
Sbjct: 114 VQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIW 171
Query: 609 NLGLIIFRDQVV 644
++GL +FR ++
Sbjct: 172 DMGLELFRTHII 183
>AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 60.9 bits (141), Expect = 6e-09
Identities = 29/84 (34%), Positives = 52/84 (61%), Gaps = 4/84 (4%)
Frame = +3
Query: 405 LYTGLKEVVTQHLETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRV 575
LY L++ H++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR
Sbjct: 2 LYKQLRQACEDHVQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRT 59
Query: 576 FVQQNE-VDNVYNLGLIIFRDQVV 644
+V QN + +++++GL +FR ++
Sbjct: 60 YVLQNSTLPSIWDMGLELFRTHII 83
>AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 60.9 bits (141), Expect = 6e-09
Identities = 29/84 (34%), Positives = 52/84 (61%), Gaps = 4/84 (4%)
Frame = +3
Query: 405 LYTGLKEVVTQHLETKV---REDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRV 575
LY L++ H++ ++ RED L S+ FL+ +N W DH M+MIR I +++DR
Sbjct: 2 LYKQLRQACEDHVQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRT 59
Query: 576 FVQQNE-VDNVYNLGLIIFRDQVV 644
+V QN + +++++GL +FR ++
Sbjct: 60 YVLQNSTLPSIWDMGLELFRTHII 83
>BC038294-1|AAH38294.1| 303|Homo sapiens C10orf46 protein protein.
Length = 303
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/140 (22%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Frame = +3
Query: 174 KYIKAPMMKSTLPKDKIPGKMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSG---L 344
K AP ST+ + K + + E Y W L AI ++ ++ +
Sbjct: 102 KAAPAPTASSTININTSTSKFLMNVITI---EDYKSTYWPKLDGAIDQLLTQSPGDYIPI 158
Query: 345 SFEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDH 524
S+E++Y Y V +H E++Y+ L + +T HLE +V +++ S + +++ N A +
Sbjct: 159 SYEQIYSCVYKCVCQQHSEQMYSDLIKKITNHLE-RVSKELQASPPDLYIERFNIALGQY 217
Query: 525 QTSMVMIRDILMYMDRVFVQ 584
++ I + +YM++ +++
Sbjct: 218 MGALQSIVPLFIYMNKFYIE 237
>AY743663-1|AAU89709.1| 306|Homo sapiens cullin protein.
Length = 306
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/140 (22%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Frame = +3
Query: 174 KYIKAPMMKSTLPKDKIPGKMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSG---L 344
K AP ST+ + K + + E Y W L AI ++ ++ +
Sbjct: 102 KAAPAPTASSTININTSTSKFLMNVITI---EDYKSTYWPKLDGAIDQLLTQSPGDYIPI 158
Query: 345 SFEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDH 524
S+E++Y Y V +H E++Y+ L + +T HLE +V +++ S + +++ N A +
Sbjct: 159 SYEQIYSCVYKCVCQQHSEQMYSDLIKKITNHLE-RVSKELQASPPDLYIERFNIALGQY 217
Query: 525 QTSMVMIRDILMYMDRVFVQ 584
++ I + +YM++ +++
Sbjct: 218 MGALQSIVPLFIYMNKFYIE 237
>AJ544771-1|CAD67614.1| 369|Homo sapiens hypothetical protein
protein.
Length = 369
Score = 50.4 bits (115), Expect = 8e-06
Identities = 32/140 (22%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Frame = +3
Query: 174 KYIKAPMMKSTLPKDKIPGKMRIRAFPMTMDEKYVERIWSLLKNAIQEIQKKNNSG---L 344
K AP ST+ + K + + E Y W L AI ++ ++ +
Sbjct: 102 KAAPAPTASSTININTSTSKFLMNVITI---EDYKSTYWPKLDGAIDQLLTQSPGDYIPI 158
Query: 345 SFEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDH 524
S+E++Y Y V +H E++Y+ L + +T HLE +V +++ S + +++ N A +
Sbjct: 159 SYEQIYSCVYKCVCQQHSEQMYSDLIKKITNHLE-RVSKELQASPPDLYIERFNIALGQY 217
Query: 525 QTSMVMIRDILMYMDRVFVQ 584
++ I + +YM++ +++
Sbjct: 218 MGALQSIVPLFIYMNKFYIE 237
>AL139407-1|CAH73727.1| 246|Homo sapiens chromosome 10 open reading
frame 46 protein.
Length = 246
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/109 (23%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +3
Query: 267 EKYVERIWSLLKNAIQEIQKKNNSG---LSFEELYRNAYTMVLHKHGERLYTGLKEVVTQ 437
E Y W L AI ++ ++ +S+E++Y Y V +H E++Y+ L + +T
Sbjct: 7 EDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITN 66
Query: 438 HLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQ 584
HLE +V +++ S + +++ N A + ++ I + +YM++ +++
Sbjct: 67 HLE-RVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIE 114
>AK097728-1|BAC05153.1| 246|Homo sapiens protein ( Homo sapiens
cDNA FLJ40409 fis, clone TESTI2037723. ).
Length = 246
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/109 (23%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +3
Query: 267 EKYVERIWSLLKNAIQEIQKKNNSG---LSFEELYRNAYTMVLHKHGERLYTGLKEVVTQ 437
E Y W L AI ++ ++ +S+E++Y Y V +H E++Y+ L + +T
Sbjct: 7 EDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITN 66
Query: 438 HLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILMYMDRVFVQ 584
HLE +V +++ S + +++ N A + ++ I + +YM++ +++
Sbjct: 67 HLE-RVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIE 114
>U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein.
Length = 577
Score = 35.5 bits (78), Expect = 0.26
Identities = 17/32 (53%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
Frame = +1
Query: 784 RAVYEEDFEKPFLHQSSEFIDW-NLEVXAENT 876
R+VYEEDFE PFL S+EF + + AEN+
Sbjct: 7 RSVYEEDFEAPFLEMSAEFFQMESQKFLAENS 38
>AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2
protein.
Length = 652
Score = 33.5 bits (73), Expect = 1.0
Identities = 13/38 (34%), Positives = 20/38 (52%)
Frame = +3
Query: 261 MDEKYVERIWSLLKNAIQEIQKKNNSGLSFEELYRNAY 374
+ E Y + W LK A++ IQ + + EELY+ Y
Sbjct: 4 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQKDY 41
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 31.5 bits (68), Expect = 4.2
Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Frame = +3
Query: 381 VLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILM 560
VL ++L +KE+V +HLET+ V H +T+N + I I
Sbjct: 1453 VLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK 1512
Query: 561 YMDRVFVQ-QNEVDNVY 608
++ + + QN++ +Y
Sbjct: 1513 QLEAINDKLQNKIQEIY 1529
>AF265555-1|AAF75772.1| 4829|Homo sapiens ubiquitin-conjugating
BIR-domain enzyme APOLLON protein.
Length = 4829
Score = 31.5 bits (68), Expect = 4.2
Identities = 16/74 (21%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Frame = +3
Query: 435 QHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILM-YMDRVFVQQNEVDNVYN 611
QHL + D LQT +N+W +H +V+ + ++ ++D FV + + N+
Sbjct: 1032 QHLHQQHHGDAAQHTRTWKLQTDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITNIPQ 1091
Query: 612 LGLIIFRDQVVRYG 653
+ + + +++ G
Sbjct: 1092 IQVTLLKNKAPGLG 1105
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 31.5 bits (68), Expect = 4.2
Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Frame = +3
Query: 381 VLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQTSMVMIRDILM 560
VL ++L +KE+V +HLET+ V H +T+N + I I
Sbjct: 1433 VLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK 1492
Query: 561 YMDRVFVQ-QNEVDNVY 608
++ + + QN++ +Y
Sbjct: 1493 QLEAINDKLQNKIQEIY 1509
>AY696296-1|AAT85804.1| 211|Homo sapiens fibroblast growth factor
20 protein.
Length = 211
Score = 30.3 bits (65), Expect = 9.7
Identities = 20/72 (27%), Positives = 33/72 (45%)
Frame = +3
Query: 348 FEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQ 527
FEE + N Y+ ++KHG+ TG + V + + R+ H F L D +
Sbjct: 143 FEENWYNTYSSNIYKHGD---TGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRP-VDPE 198
Query: 528 TSMVMIRDILMY 563
+ +D+LMY
Sbjct: 199 RVPELYKDLLMY 210
>AB044277-1|BAB03633.1| 211|Homo sapiens FGF-20 protein.
Length = 211
Score = 30.3 bits (65), Expect = 9.7
Identities = 20/72 (27%), Positives = 33/72 (45%)
Frame = +3
Query: 348 FEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQ 527
FEE + N Y+ ++KHG+ TG + V + + R+ H F L D +
Sbjct: 143 FEENWYNTYSSNIYKHGD---TGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRP-VDPE 198
Query: 528 TSMVMIRDILMY 563
+ +D+LMY
Sbjct: 199 RVPELYKDLLMY 210
>AB030648-1|BAB03530.1| 211|Homo sapiens fibroblast growth factor
20 (FGF-20) protein.
Length = 211
Score = 30.3 bits (65), Expect = 9.7
Identities = 20/72 (27%), Positives = 33/72 (45%)
Frame = +3
Query: 348 FEELYRNAYTMVLHKHGERLYTGLKEVVTQHLETKVREDVLHSLHNGFLQTLNNAWTDHQ 527
FEE + N Y+ ++KHG+ TG + V + + R+ H F L D +
Sbjct: 143 FEENWYNTYSSNIYKHGD---TGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRP-VDPE 198
Query: 528 TSMVMIRDILMY 563
+ +D+LMY
Sbjct: 199 RVPELYKDLLMY 210
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,771,774
Number of Sequences: 237096
Number of extensions: 2519563
Number of successful extensions: 4774
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 4524
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4756
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11326166088
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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