Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP15_F_N17
(921 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 235 1e-61
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 235 1e-61
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 235 1e-61
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 235 1e-61
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 195 2e-49
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 195 2e-49
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 192 2e-48
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 192 2e-48
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 192 2e-48
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 175 1e-43
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 175 1e-43
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 175 1e-43
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 174 3e-43
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 169 1e-41
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 168 3e-41
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 168 3e-41
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 168 3e-41
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 168 3e-41
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 168 3e-41
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 168 3e-41
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 166 9e-41
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 166 9e-41
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 164 3e-40
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 158 2e-38
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 158 2e-38
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 158 2e-38
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 154 4e-37
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 140 6e-33
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 138 3e-32
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 138 3e-32
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 133 7e-31
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 133 7e-31
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 133 7e-31
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 133 7e-31
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 133 7e-31
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 133 7e-31
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 132 2e-30
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 132 2e-30
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 132 2e-30
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 132 2e-30
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 131 3e-30
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 131 3e-30
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 131 3e-30
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 131 3e-30
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 131 3e-30
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 131 3e-30
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 131 3e-30
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 131 3e-30
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 131 3e-30
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 131 3e-30
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 131 3e-30
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 131 3e-30
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 130 5e-30
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 130 7e-30
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 130 7e-30
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 130 7e-30
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 130 7e-30
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 130 7e-30
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 130 9e-30
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 130 9e-30
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 130 9e-30
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 130 9e-30
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 130 9e-30
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 130 9e-30
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 130 9e-30
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 130 9e-30
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 130 9e-30
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 130 9e-30
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 130 9e-30
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 129 1e-29
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 129 1e-29
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 129 1e-29
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 129 1e-29
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 129 1e-29
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 129 1e-29
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 129 1e-29
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 129 1e-29
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 129 1e-29
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 129 1e-29
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 129 2e-29
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 129 2e-29
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 129 2e-29
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 129 2e-29
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 129 2e-29
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 129 2e-29
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 129 2e-29
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 129 2e-29
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 129 2e-29
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 128 4e-29
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 128 4e-29
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 128 4e-29
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 128 4e-29
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 128 4e-29
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 128 4e-29
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 128 4e-29
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 128 4e-29
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 128 4e-29
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 128 4e-29
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 128 4e-29
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 128 4e-29
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 127 5e-29
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 127 6e-29
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 127 6e-29
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 127 6e-29
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 127 6e-29
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 127 6e-29
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 127 6e-29
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 127 6e-29
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 126 1e-28
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 126 1e-28
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 126 1e-28
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 126 1e-28
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 126 1e-28
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 126 1e-28
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 126 1e-28
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 126 1e-28
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 126 1e-28
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 126 1e-28
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 126 1e-28
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 125 2e-28
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 125 3e-28
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 125 3e-28
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 125 3e-28
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 125 3e-28
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 125 3e-28
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 125 3e-28
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 124 3e-28
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 124 3e-28
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 124 3e-28
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 124 3e-28
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 124 3e-28
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 124 3e-28
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 124 3e-28
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 124 3e-28
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 124 3e-28
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 124 5e-28
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 124 5e-28
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 124 5e-28
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 124 5e-28
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 124 5e-28
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 124 5e-28
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 124 5e-28
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 124 5e-28
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 124 5e-28
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 124 6e-28
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 124 6e-28
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 124 6e-28
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 124 6e-28
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 124 6e-28
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 124 6e-28
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 124 6e-28
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 124 6e-28
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 124 6e-28
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 124 6e-28
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 124 6e-28
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 124 6e-28
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 124 6e-28
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 124 6e-28
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 124 6e-28
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 123 8e-28
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 123 8e-28
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 123 8e-28
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 123 8e-28
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 123 8e-28
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 123 8e-28
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 123 8e-28
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 123 8e-28
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 123 8e-28
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 123 8e-28
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 123 8e-28
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 123 1e-27
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 123 1e-27
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 123 1e-27
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 123 1e-27
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 123 1e-27
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 123 1e-27
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 123 1e-27
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 122 1e-27
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 122 1e-27
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 122 1e-27
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 122 2e-27
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 121 3e-27
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 121 3e-27
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 121 4e-27
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 121 4e-27
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 121 4e-27
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 120 6e-27
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 120 6e-27
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 120 7e-27
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 120 7e-27
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 120 7e-27
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 120 7e-27
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 120 7e-27
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 120 7e-27
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 120 7e-27
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 120 1e-26
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 92 1e-26
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 119 1e-26
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 119 1e-26
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 119 1e-26
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 119 1e-26
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 119 1e-26
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 119 2e-26
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 119 2e-26
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 119 2e-26
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 119 2e-26
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 119 2e-26
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 119 2e-26
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 119 2e-26
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 119 2e-26
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 119 2e-26
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 119 2e-26
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 119 2e-26
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 119 2e-26
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 119 2e-26
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 119 2e-26
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 119 2e-26
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 119 2e-26
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 119 2e-26
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 119 2e-26
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 118 2e-26
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 118 3e-26
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 118 3e-26
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 118 3e-26
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 118 3e-26
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 118 3e-26
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 118 3e-26
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 118 3e-26
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 118 3e-26
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 118 3e-26
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 118 3e-26
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 118 4e-26
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 118 4e-26
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 118 4e-26
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 118 4e-26
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 118 4e-26
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 118 4e-26
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 118 4e-26
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 118 4e-26
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 118 4e-26
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 118 4e-26
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 118 4e-26
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 118 4e-26
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 118 4e-26
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 118 4e-26
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 118 4e-26
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 117 5e-26
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 117 5e-26
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 117 5e-26
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 117 5e-26
BC146770-1|AAI46771.1| 1558|Homo sapiens mitogen-activated prote... 117 5e-26
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 117 5e-26
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 117 5e-26
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 117 5e-26
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 117 5e-26
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 117 7e-26
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 117 7e-26
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 116 9e-26
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 116 9e-26
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 116 9e-26
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 116 9e-26
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 116 9e-26
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 116 9e-26
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 116 9e-26
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 116 9e-26
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 116 9e-26
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 116 9e-26
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 116 9e-26
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 116 9e-26
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 116 9e-26
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 116 9e-26
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 116 9e-26
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 116 9e-26
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 116 1e-25
AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein. 116 1e-25
AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein. 116 1e-25
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 116 2e-25
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 116 2e-25
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 116 2e-25
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 116 2e-25
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 116 2e-25
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 116 2e-25
AL596452-3|CAI41309.1| 1498|Homo sapiens mitogen-activated prote... 116 2e-25
AL596452-2|CAI41310.1| 1544|Homo sapiens mitogen-activated prote... 116 2e-25
AL591045-2|CAH70639.1| 1498|Homo sapiens mitogen-activated prote... 116 2e-25
AL591045-1|CAH70640.1| 1544|Homo sapiens mitogen-activated prote... 116 2e-25
AL139393-2|CAI20815.1| 1498|Homo sapiens mitogen-activated prote... 116 2e-25
AL139393-1|CAI20816.1| 1544|Homo sapiens mitogen-activated prote... 116 2e-25
AL109942-4|CAI21477.1| 1498|Homo sapiens mitogen-activated prote... 116 2e-25
AL109942-3|CAC12766.2| 1544|Homo sapiens mitogen-activated prote... 116 2e-25
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 116 2e-25
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 116 2e-25
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 115 2e-25
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 115 2e-25
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 115 2e-25
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 115 2e-25
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 115 2e-25
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 115 2e-25
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 115 2e-25
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 115 2e-25
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 115 3e-25
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 115 3e-25
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 115 3e-25
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 115 3e-25
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 115 3e-25
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 115 3e-25
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 115 3e-25
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 114 4e-25
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 114 4e-25
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 114 4e-25
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 114 4e-25
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 114 4e-25
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 114 4e-25
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 114 4e-25
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 114 4e-25
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 114 4e-25
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 114 4e-25
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 114 4e-25
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 114 4e-25
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 114 4e-25
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 114 5e-25
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 114 5e-25
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 114 5e-25
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 114 5e-25
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 114 5e-25
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 114 5e-25
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 114 5e-25
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 114 5e-25
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 114 5e-25
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 114 5e-25
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 114 5e-25
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 114 5e-25
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 114 5e-25
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 114 5e-25
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 114 5e-25
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 114 5e-25
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 114 5e-25
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 114 5e-25
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 114 5e-25
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 114 5e-25
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 113 6e-25
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 113 6e-25
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 113 9e-25
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 113 9e-25
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 113 9e-25
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 113 9e-25
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 113 9e-25
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 113 9e-25
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 113 1e-24
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 112 2e-24
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 112 2e-24
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 112 2e-24
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 112 2e-24
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 112 2e-24
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 112 2e-24
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 112 2e-24
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 112 2e-24
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 112 2e-24
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 112 2e-24
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 111 3e-24
BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacti... 111 3e-24
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 111 3e-24
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 111 3e-24
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 111 3e-24
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 111 3e-24
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 111 3e-24
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 111 3e-24
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 111 3e-24
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 111 3e-24
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 111 3e-24
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 111 3e-24
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 111 3e-24
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 111 3e-24
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 111 3e-24
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 111 3e-24
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 111 3e-24
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 111 3e-24
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 111 3e-24
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 111 3e-24
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 111 3e-24
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 111 3e-24
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 111 3e-24
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 111 3e-24
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 111 5e-24
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 111 5e-24
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 111 5e-24
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 111 5e-24
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 111 5e-24
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 111 5e-24
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 111 5e-24
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 111 5e-24
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 111 5e-24
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 111 5e-24
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 111 5e-24
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 111 5e-24
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 111 5e-24
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 111 5e-24
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 111 5e-24
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 111 5e-24
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 110 6e-24
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 110 6e-24
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 110 8e-24
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 110 8e-24
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 110 8e-24
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 110 8e-24
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 110 8e-24
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 110 8e-24
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 110 8e-24
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 110 8e-24
AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis ... 110 8e-24
AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis... 110 8e-24
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 110 8e-24
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 110 8e-24
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 109 1e-23
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 109 1e-23
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 109 1e-23
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 109 1e-23
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 109 1e-23
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 109 1e-23
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 109 1e-23
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 109 1e-23
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 109 1e-23
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 109 1e-23
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 109 1e-23
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 109 2e-23
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 109 2e-23
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 109 2e-23
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 109 2e-23
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 109 2e-23
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 109 2e-23
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 109 2e-23
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 109 2e-23
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 109 2e-23
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 108 2e-23
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 108 2e-23
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 108 2e-23
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 108 2e-23
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 108 2e-23
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 108 2e-23
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 108 2e-23
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 108 2e-23
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 108 2e-23
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 108 3e-23
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 108 3e-23
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 108 3e-23
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 108 3e-23
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 108 3e-23
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 108 3e-23
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 108 3e-23
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 108 3e-23
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 108 3e-23
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 108 3e-23
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 108 3e-23
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 108 3e-23
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 108 3e-23
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 108 3e-23
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 107 4e-23
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 107 4e-23
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 107 4e-23
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 107 4e-23
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 107 4e-23
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 107 4e-23
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 107 6e-23
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 107 6e-23
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 107 7e-23
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 107 7e-23
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 107 7e-23
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 107 7e-23
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 107 7e-23
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 107 7e-23
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 107 7e-23
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 235 bits (576), Expect = 1e-61
Identities = 113/249 (45%), Positives = 166/249 (66%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K ++ +G+G +G V+LC + L I+K I + ++ Q NE ++L + HP
Sbjct: 2 EKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
N+I +Y+ F + +MI+MEYA G LAEF+ RC ++++E IL +F QILL + ++H
Sbjct: 62 NVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHT 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY 653
I+HRDLK +NILL K+ ++VKIGDFGISK+L+S K TV+GTP Y++PELCEG+PY
Sbjct: 122 HLILHRDLKTQNILL-DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY 180
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ KSDIWALGC+LYE+ + KRAFE+ L LV I SG+ PI Y ++ L+ S+L
Sbjct: 181 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS-DRYSPELRQLVLSLL 239
Query: 834 SILPNKGRP 860
S+ P + P
Sbjct: 240 SLEPAQRPP 248
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 235 bits (576), Expect = 1e-61
Identities = 113/249 (45%), Positives = 166/249 (66%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K ++ +G+G +G V+LC + L I+K I + ++ Q NE ++L + HP
Sbjct: 2 EKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
N+I +Y+ F + +MI+MEYA G LAEF+ RC ++++E IL +F QILL + ++H
Sbjct: 62 NVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHT 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY 653
I+HRDLK +NILL K+ ++VKIGDFGISK+L+S K TV+GTP Y++PELCEG+PY
Sbjct: 122 HLILHRDLKTQNILL-DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY 180
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ KSDIWALGC+LYE+ + KRAFE+ L LV I SG+ PI Y ++ L+ S+L
Sbjct: 181 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS-DRYSPELRQLVLSLL 239
Query: 834 SILPNKGRP 860
S+ P + P
Sbjct: 240 SLEPAQRPP 248
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 235 bits (576), Expect = 1e-61
Identities = 113/249 (45%), Positives = 166/249 (66%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K ++ +G+G +G V+LC + L I+K I + ++ Q NE ++L + HP
Sbjct: 2 EKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
N+I +Y+ F + +MI+MEYA G LAEF+ RC ++++E IL +F QILL + ++H
Sbjct: 62 NVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHT 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY 653
I+HRDLK +NILL K+ ++VKIGDFGISK+L+S K TV+GTP Y++PELCEG+PY
Sbjct: 122 HLILHRDLKTQNILL-DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY 180
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ KSDIWALGC+LYE+ + KRAFE+ L LV I SG+ PI Y ++ L+ S+L
Sbjct: 181 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS-DRYSPELRQLVLSLL 239
Query: 834 SILPNKGRP 860
S+ P + P
Sbjct: 240 SLEPAQRPP 248
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 235 bits (576), Expect = 1e-61
Identities = 113/249 (45%), Positives = 166/249 (66%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K ++ +G+G +G V+LC + L I+K I + ++ Q NE ++L + HP
Sbjct: 2 EKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
N+I +Y+ F + +MI+MEYA G LAEF+ RC ++++E IL +F QILL + ++H
Sbjct: 62 NVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHT 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY 653
I+HRDLK +NILL K+ ++VKIGDFGISK+L+S K TV+GTP Y++PELCEG+PY
Sbjct: 122 HLILHRDLKTQNILL-DKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY 180
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ KSDIWALGC+LYE+ + KRAFE+ L LV I SG+ PI Y ++ L+ S+L
Sbjct: 181 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS-DRYSPELRQLVLSLL 239
Query: 834 SILPNKGRP 860
S+ P + P
Sbjct: 240 SLEPAQRPP 248
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 195 bits (476), Expect = 2e-49
Identities = 96/250 (38%), Positives = 152/250 (60%), Gaps = 1/250 (0%)
Frame = +3
Query: 117 KLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPN 296
K ++K IG+G +G YL + + ++K+I Q ++ EV +L MKHPN
Sbjct: 3 KYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 62
Query: 297 IISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
I++F+ F + I MEY G+L + + + + +++IL +F QI LG+ +IH+
Sbjct: 63 IVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDR 122
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
I+HRD+KA+NI L+ K G++ K+GDFGI+++L ++ + + T IGTPYYL+PE+C+ +PY
Sbjct: 123 KILHRDIKAQNIFLS-KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPY 181
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ K+DIW+LGC+LYE+CT K FE L LV I PI + R + LI +
Sbjct: 182 NNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPIS-PGFSRELHSLISQLF 240
Query: 834 SILPNKGRPS 863
+ P + RPS
Sbjct: 241 QVSP-RDRPS 249
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 195 bits (476), Expect = 2e-49
Identities = 96/250 (38%), Positives = 152/250 (60%), Gaps = 1/250 (0%)
Frame = +3
Query: 117 KLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPN 296
K ++K IG+G +G YL + + ++K+I Q ++ EV +L MKHPN
Sbjct: 3 KYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 62
Query: 297 IISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
I++F+ F + I MEY G+L + + + + +++IL +F QI LG+ +IH+
Sbjct: 63 IVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDR 122
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
I+HRD+KA+NI L+ K G++ K+GDFGI+++L ++ + + T IGTPYYL+PE+C+ +PY
Sbjct: 123 KILHRDIKAQNIFLS-KNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPY 181
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSML 833
+ K+DIW+LGC+LYE+CT K FE L LV I PI + R + LI +
Sbjct: 182 NNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPIS-PGFSRELHSLISQLF 240
Query: 834 SILPNKGRPS 863
+ P + RPS
Sbjct: 241 QVSP-RDRPS 249
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 192 bits (467), Expect = 2e-48
Identities = 97/251 (38%), Positives = 160/251 (63%), Gaps = 1/251 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K L+ IG+G++G L ++ E+ ++K+I ++ + ++ EV +L+ MKHP
Sbjct: 2 EKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ + + F + I M+Y G+L + + + + ++++IL +F QI L + ++H+
Sbjct: 62 NIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHD 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQP 650
I+HRD+K++NI LT K G V++GDFGI+++L S + + T IGTPYYL+PE+CE +P
Sbjct: 122 RKILHRDIKSQNIFLT-KDGT-VQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKP 179
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSM 830
Y+ KSDIWALGC+LYE+CT K AFE+ ++ LV I SGS P+ L Y ++ L+ +
Sbjct: 180 YNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSL-HYSYDLRSLVSQL 238
Query: 831 LSILPNKGRPS 863
P + RPS
Sbjct: 239 FKRNP-RDRPS 248
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 192 bits (467), Expect = 2e-48
Identities = 97/251 (38%), Positives = 160/251 (63%), Gaps = 1/251 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K L+ IG+G++G L ++ E+ ++K+I ++ + ++ EV +L+ MKHP
Sbjct: 2 EKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ + + F + I M+Y G+L + + + + ++++IL +F QI L + ++H+
Sbjct: 62 NIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHD 121
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQP 650
I+HRD+K++NI LT K G V++GDFGI+++L S + + T IGTPYYL+PE+CE +P
Sbjct: 122 RKILHRDIKSQNIFLT-KDGT-VQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKP 179
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSM 830
Y+ KSDIWALGC+LYE+CT K AFE+ ++ LV I SGS P+ L Y ++ L+ +
Sbjct: 180 YNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSL-HYSYDLRSLVSQL 238
Query: 831 LSILPNKGRPS 863
P + RPS
Sbjct: 239 FKRNP-RDRPS 248
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 192 bits (467), Expect = 2e-48
Identities = 97/251 (38%), Positives = 160/251 (63%), Gaps = 1/251 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K L+ IG+G++G L ++ E+ ++K+I ++ + ++ EV +L+ MKHP
Sbjct: 9 EKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHP 68
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ + + F + I M+Y G+L + + + + ++++IL +F QI L + ++H+
Sbjct: 69 NIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHD 128
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQP 650
I+HRD+K++NI LT K G V++GDFGI+++L S + + T IGTPYYL+PE+CE +P
Sbjct: 129 RKILHRDIKSQNIFLT-KDGT-VQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKP 186
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSM 830
Y+ KSDIWALGC+LYE+CT K AFE+ ++ LV I SGS P+ L Y ++ L+ +
Sbjct: 187 YNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSL-HYSYDLRSLVSQL 245
Query: 831 LSILPNKGRPS 863
P + RPS
Sbjct: 246 FKRNP-RDRPS 255
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 175 bits (427), Expect = 1e-43
Identities = 92/249 (36%), Positives = 154/249 (61%), Gaps = 3/249 (1%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+ IG+G++G L ++ ++ + +K+I+L K + Q+ E +L+ MKHPNI++
Sbjct: 6 VLRMIGEGSFGRALLVQHESSNQMFAMKEIRL-PKSFSNTQNSRKEAVLLAKMKHPNIVA 64
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
F + F AE ++ I MEY G+L + + + ++ ++ IL +F Q+ LGV++IH ++
Sbjct: 65 FKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVL 124
Query: 486 HRDLKAENILLT--GKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQPYD 656
HRD+K++NI LT GK VK+GDFG +++L++ T +GTPYY+ PE+ E PY+
Sbjct: 125 HRDIKSKNIFLTQNGK----VKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYN 180
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
KSDIW+LGC+LYE+CT K F++ + L+ + G + P+ Y +Q L+ M
Sbjct: 181 NKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLP-SHYSYELQFLVKQMFK 239
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 240 RNPSH-RPS 247
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 175 bits (427), Expect = 1e-43
Identities = 92/249 (36%), Positives = 154/249 (61%), Gaps = 3/249 (1%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+ IG+G++G L ++ ++ + +K+I+L K + Q+ E +L+ MKHPNI++
Sbjct: 6 VLRMIGEGSFGRALLVQHESSNQMFAMKEIRL-PKSFSNTQNSRKEAVLLAKMKHPNIVA 64
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
F + F AE ++ I MEY G+L + + + ++ ++ IL +F Q+ LGV++IH ++
Sbjct: 65 FKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVL 124
Query: 486 HRDLKAENILLT--GKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQPYD 656
HRD+K++NI LT GK VK+GDFG +++L++ T +GTPYY+ PE+ E PY+
Sbjct: 125 HRDIKSKNIFLTQNGK----VKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYN 180
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
KSDIW+LGC+LYE+CT K F++ + L+ + G + P+ Y +Q L+ M
Sbjct: 181 NKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLP-SHYSYELQFLVKQMFK 239
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 240 RNPSH-RPS 247
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 175 bits (427), Expect = 1e-43
Identities = 92/249 (36%), Positives = 154/249 (61%), Gaps = 3/249 (1%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+ IG+G++G L ++ ++ + +K+I+L K + Q+ E +L+ MKHPNI++
Sbjct: 27 VLRMIGEGSFGRALLVQHESSNQMFAMKEIRL-PKSFSNTQNSRKEAVLLAKMKHPNIVA 85
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
F + F AE ++ I MEY G+L + + + ++ ++ IL +F Q+ LGV++IH ++
Sbjct: 86 FKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVL 145
Query: 486 HRDLKAENILLT--GKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQPYD 656
HRD+K++NI LT GK VK+GDFG +++L++ T +GTPYY+ PE+ E PY+
Sbjct: 146 HRDIKSKNIFLTQNGK----VKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYN 201
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
KSDIW+LGC+LYE+CT K F++ + L+ + G + P+ Y +Q L+ M
Sbjct: 202 NKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLP-SHYSYELQFLVKQMFK 260
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 261 RNPSH-RPS 268
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 174 bits (424), Expect = 3e-43
Identities = 92/249 (36%), Positives = 153/249 (61%), Gaps = 3/249 (1%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+ IG+G +G L ++ ++ + +K+I+L K + Q+ E +L+ MKHPNI++
Sbjct: 6 VLRMIGEGFFGRALLVQHESSNQMFAMKEIRL-PKSFSNTQNSRKEAVLLAKMKHPNIVA 64
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
F + F AE ++ I MEY G+L + + + ++ ++ IL +F Q+ LGV++IH ++
Sbjct: 65 FKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVL 124
Query: 486 HRDLKAENILLT--GKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQPYD 656
HRD+K++NI LT GK VK+GDFG +++L++ T +GTPYY+ PE+ E PY+
Sbjct: 125 HRDIKSKNIFLTQNGK----VKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYN 180
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
KSDIW+LGC+LYE+CT K F++ + L+ + G + P+ Y +Q L+ M
Sbjct: 181 NKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLP-SHYSYELQFLVKQMFK 239
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 240 RNPSH-RPS 247
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 169 bits (411), Expect = 1e-41
Identities = 88/247 (35%), Positives = 148/247 (59%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
L+ +GKG+YG V L ++ + ++K + L + + E ++LS +KHPNI+++
Sbjct: 9 LRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTY 68
Query: 309 YQCFYAEDYVM-ISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
+ + D ++ I M + G+L + + Q++ + +++ +F QI + + Y+H I+
Sbjct: 69 KESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHIL 128
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLAS-AKKTSTVIGTPYYLAPELCEGQPYDTK 662
HRDLK +N+ LT I+K+GD GI+++L + ST+IGTPYY++PEL +PY+ K
Sbjct: 129 HRDLKTQNVFLTRTN--IIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYK 186
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
SD+WALGC +YEM T K AF ++ + LV I G + P+ Y + +LI +MLS
Sbjct: 187 SDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRD-YSPELAELIRTMLSKR 245
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 246 PEE-RPS 251
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 55 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 175 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 232
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 233 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 292
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 293 PEQ-RPT 298
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 55 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 175 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 232
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 233 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 292
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 293 PEQ-RPT 298
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 55 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 175 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 232
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 233 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 292
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 293 PEQ-RPT 298
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 55 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 175 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 232
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 233 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 292
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 293 PEQ-RPT 298
>AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 312
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 55 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 175 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 232
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 233 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 292
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 293 PEQ-RPT 298
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 168 bits (408), Expect = 3e-41
Identities = 84/247 (34%), Positives = 145/247 (58%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
++ +G+G +G L E+ L + K++ L ++ +D NE+ IL+ ++H NII++
Sbjct: 87 IRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 146
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++I +EY GNL + + + ++ ++E +++Y QI+ VS IH I+H
Sbjct: 147 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 206
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKS 665
RD+K NI LT ++K+GD+G++K L S T++GTPYY++PELC+G Y+ KS
Sbjct: 207 RDIKTLNIFLT--KANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKS 264
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGL-VKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
DIWA+GC+++E+ T KR F++ + L VK + +D Y + ++ S L
Sbjct: 265 DIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQD 324
Query: 843 PNKGRPS 863
P + RP+
Sbjct: 325 PEQ-RPT 330
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 166 bits (404), Expect = 9e-41
Identities = 88/247 (35%), Positives = 147/247 (59%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
L+ +GKG+YG V L ++ + ++K + L + + E ++LS +KHPNI+++
Sbjct: 9 LRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTY 68
Query: 309 YQCFYAEDYVM-ISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
+ + D ++ I M + G+L + + Q++ + +++ +F QI + + Y+H I+
Sbjct: 69 KESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHIL 128
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLAS-AKKTSTVIGTPYYLAPELCEGQPYDTK 662
HRDLK +N+ LT I+K+GD GI+++L + ST+IGTPYY++PEL +PY+ K
Sbjct: 129 HRDLKTQNVFLTRTN--IIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYK 186
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
SD+WALGC +YEM T K AF ++ + LV I G + P Y + +LI +MLS
Sbjct: 187 SDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL-PAMPRDYSPELAELIRTMLSKR 245
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 246 PEE-RPS 251
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 166 bits (404), Expect = 9e-41
Identities = 88/247 (35%), Positives = 147/247 (59%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
L+ +GKG+YG V L ++ + ++K + L + + E ++LS +KHPNI+++
Sbjct: 9 LRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTY 68
Query: 309 YQCFYAEDYVM-ISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
+ + D ++ I M + G+L + + Q++ + +++ +F QI + + Y+H I+
Sbjct: 69 KESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHIL 128
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLAS-AKKTSTVIGTPYYLAPELCEGQPYDTK 662
HRDLK +N+ LT I+K+GD GI+++L + ST+IGTPYY++PEL +PY+ K
Sbjct: 129 HRDLKTQNVFLTRTN--IIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYK 186
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
SD+WALGC +YEM T K AF ++ + LV I G + P Y + +LI +MLS
Sbjct: 187 SDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL-PAMPRDYSPELAELIRTMLSKR 245
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 246 PEE-RPS 251
>EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein.
Length = 841
Score = 164 bits (399), Expect = 3e-40
Identities = 87/247 (35%), Positives = 147/247 (59%), Gaps = 2/247 (0%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISF 308
L+ +GKG+YG V L ++ + ++K + L + + E ++LS +KHP+I+++
Sbjct: 9 LRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPDIVTY 68
Query: 309 YQCFYAEDYVM-ISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
+ + D ++ I M + G+L + + Q++ + +++ +F QI + + Y+H I+
Sbjct: 69 KESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHIL 128
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLAS-AKKTSTVIGTPYYLAPELCEGQPYDTK 662
HRDLK +N+ LT I+K+GD GI+++L + ST+IGTPYY++PEL +PY+ K
Sbjct: 129 HRDLKTQNVFLTRTN--IIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYK 186
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSIL 842
SD+WALGC +YEM T K AF ++ + LV I G + P Y + +LI +MLS
Sbjct: 187 SDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL-PAMPRDYSPELAELIRTMLSKR 245
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 246 PEE-RPS 251
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 158 bits (384), Expect = 2e-38
Identities = 89/249 (35%), Positives = 145/249 (58%), Gaps = 7/249 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHE---NHLLTIVKDIQLNAKIQQHEQDIAN-EVRILSTMKHPNIIS 305
+G G++G VYL + + L ++K+I + ++ +E AN E ++LS + HP I+
Sbjct: 35 LGSGSFGTVYLVSDKKAKRGEELKVLKEISVG-ELNPNETVQANLEAQLLSKLDHPAIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
F+ F +D I EY +L + + Y + ++ + +I+ +F Q+LLGV Y+H
Sbjct: 94 FHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERR 153
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKML-ASAKKTSTVIGTPYYLAPELCEGQPYD 656
I+HRDLK++N+ L ++KIGDFG+S++L S +T+ GTP+Y++PE + Q YD
Sbjct: 154 ILHRDLKSKNVFLKNN---LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYD 210
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
TKSDIW+L C+LYEMC AF + +V I G P Y + + +++SML+
Sbjct: 211 TKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDT-PSLPERYPKELNAIMESMLN 269
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 270 KNPSL-RPS 277
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 158 bits (384), Expect = 2e-38
Identities = 89/249 (35%), Positives = 145/249 (58%), Gaps = 7/249 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHE---NHLLTIVKDIQLNAKIQQHEQDIAN-EVRILSTMKHPNIIS 305
+G G++G VYL + + L ++K+I + ++ +E AN E ++LS + HP I+
Sbjct: 35 LGSGSFGTVYLVSDKKAKRGEELKVLKEISVG-ELNPNETVQANLEAQLLSKLDHPAIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
F+ F +D I EY +L + + Y + ++ + +I+ +F Q+LLGV Y+H
Sbjct: 94 FHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERR 153
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKML-ASAKKTSTVIGTPYYLAPELCEGQPYD 656
I+HRDLK++N+ L ++KIGDFG+S++L S +T+ GTP+Y++PE + Q YD
Sbjct: 154 ILHRDLKSKNVFLKNN---LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYD 210
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
TKSDIW+L C+LYEMC AF + +V I G P Y + + +++SML+
Sbjct: 211 TKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDT-PSLPERYPKELNAIMESMLN 269
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 270 KNPSL-RPS 277
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 158 bits (384), Expect = 2e-38
Identities = 89/249 (35%), Positives = 145/249 (58%), Gaps = 7/249 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHE---NHLLTIVKDIQLNAKIQQHEQDIAN-EVRILSTMKHPNIIS 305
+G G++G VYL + + L ++K+I + ++ +E AN E ++LS + HP I+
Sbjct: 35 LGSGSFGTVYLVSDKKAKRGEELKVLKEISVG-ELNPNETVQANLEAQLLSKLDHPAIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
F+ F +D I EY +L + + Y + ++ + +I+ +F Q+LLGV Y+H
Sbjct: 94 FHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERR 153
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKML-ASAKKTSTVIGTPYYLAPELCEGQPYD 656
I+HRDLK++N+ L ++KIGDFG+S++L S +T+ GTP+Y++PE + Q YD
Sbjct: 154 ILHRDLKSKNVFLKNN---LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYD 210
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
TKSDIW+L C+LYEMC AF + +V I G P Y + + +++SML+
Sbjct: 211 TKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDT-PSLPERYPKELNAIMESMLN 269
Query: 837 ILPNKGRPS 863
P+ RPS
Sbjct: 270 KNPSL-RPS 277
>Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein.
Length = 459
Score = 154 bits (374), Expect = 4e-37
Identities = 80/204 (39%), Positives = 128/204 (62%), Gaps = 3/204 (1%)
Frame = +3
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E + + MKHPNI++F + F AE ++ I MEY G+L + + + ++ ++ IL +F
Sbjct: 3 EAVLSAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFT 62
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLT--GKYGIIVKIGDFGISKMLASAKKTS-TVIGT 611
Q+ LGV++IH ++HRD+K++NI LT GK VK+GDFG +++L++ + T +GT
Sbjct: 63 QMCLGVNHIHKKRVLHRDIKSKNIFLTQNGK----VKLGDFGSARLLSNPMAFACTYVGT 118
Query: 612 PYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
PYY+ PE+ E PY+ KSDIW+LGC+LYE+CT K F++ + L+ + G + P+
Sbjct: 119 PYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLP-S 177
Query: 792 LYDRXMQDLIDSMLSILPNKGRPS 863
Y +Q L+ M P+ RPS
Sbjct: 178 HYSYELQFLVKQMFKRNPSH-RPS 200
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 140 bits (339), Expect = 6e-33
Identities = 79/219 (36%), Positives = 121/219 (55%), Gaps = 2/219 (0%)
Frame = +3
Query: 117 KLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNA-KIQQHEQDIANEVRILSTMKHP 293
+ + +T+GKGTYG V + + +K I+ + K +Q I E+ I+S++ HP
Sbjct: 91 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 150
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
+IIS Y+ F +D ++I MEYA+ G L +++ R + + + E +F QI+ V Y H
Sbjct: 151 HIISIYEVFENKDKIVIIMEYASKGELYDYISER--RRLSERETRHFFRQIVSAVHYCHK 208
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY 653
++HRDLK ENILL I KI DFG+S + K T G+P Y +PE+ G+PY
Sbjct: 209 NGVVHRDLKLENILLDDNCNI--KIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPY 266
Query: 654 -DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
+ D WALG LLY + F+ L++ I+SG
Sbjct: 267 RGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSG 305
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 138 bits (334), Expect = 3e-32
Identities = 78/219 (35%), Positives = 118/219 (53%), Gaps = 1/219 (0%)
Frame = +3
Query: 117 KLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPN 296
+ L+T+GKGTYG V L+ I + K +Q I E+ I+S++ HP+
Sbjct: 52 RYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 297 IISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
II+ ++ F ++I MEYA+ G+L +++ R Q + + E +F QI+ V Y H
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISER--QQLSEREARHFFRQIVSAVHYCHQN 169
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY- 653
++HRDLK ENILL I KI DFG+S + K T G+P Y +PE+ G+PY
Sbjct: 170 RVVHRDLKLENILLDANGNI--KIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYT 227
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS 770
+ D W+LG LLY + F+ LVK I++G+
Sbjct: 228 GPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGA 266
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 138 bits (334), Expect = 3e-32
Identities = 78/219 (35%), Positives = 118/219 (53%), Gaps = 1/219 (0%)
Frame = +3
Query: 117 KLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPN 296
+ L+T+GKGTYG V L+ I + K +Q I E+ I+S++ HP+
Sbjct: 52 RYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 297 IISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
II+ ++ F ++I MEYA+ G+L +++ R Q + + E +F QI+ V Y H
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISER--QQLSEREARHFFRQIVSAVHYCHQN 169
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPY- 653
++HRDLK ENILL I KI DFG+S + K T G+P Y +PE+ G+PY
Sbjct: 170 RVVHRDLKLENILLDANGNI--KIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYT 227
Query: 654 DTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS 770
+ D W+LG LLY + F+ LVK I++G+
Sbjct: 228 GPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGA 266
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 7 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 64
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 65 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 122
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 123 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 180
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 239
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 240 M-STDCENLLKKFLILNPSK 258
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 7 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 64
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 65 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 122
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 123 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 180
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 239
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 240 M-STDCENLLKKFLILNPSK 258
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 40 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 97
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 98 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 155
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 213
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 214 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 272
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 273 M-STDCENLLKKFLILNPSK 291
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 30 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 87
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 88 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 145
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 146 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 203
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 204 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 262
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 263 M-STDCENLLKKFLILNPSK 281
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 7 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 64
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 65 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 122
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 123 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 180
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 239
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 240 M-STDCENLLKKFLILNPSK 258
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 133 bits (322), Expect = 7e-31
Identities = 88/260 (33%), Positives = 127/260 (48%), Gaps = 1/260 (0%)
Frame = +3
Query: 75 SGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDI 254
S D Q N +L LKTIGKG + V L + VK I Q +
Sbjct: 40 SATSADEQPHIGNYRL--LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL 97
Query: 255 ANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFY 434
EVRI+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E
Sbjct: 98 FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAK 155
Query: 435 FCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTP 614
F QI+ V Y H I+HRDLKAEN+LL I KI DFG S K T G+P
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNI--KIADFGFSNEFTFGNKLDTFCGSP 213
Query: 615 YYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLV 791
Y APEL +G+ YD + D+W+LG +LY + + F+ + L L + + G + I
Sbjct: 214 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFY 272
Query: 792 LYDRXMQDLIDSMLSILPNK 851
+ ++L+ L + P+K
Sbjct: 273 M-STDCENLLKKFLILNPSK 291
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 132 bits (318), Expect = 2e-30
Identities = 82/227 (36%), Positives = 114/227 (50%), Gaps = 1/227 (0%)
Frame = +3
Query: 90 DLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVR 269
D Q N +L KTIGKG + V L + VK I Q + EVR
Sbjct: 52 DEQPHIGNYRLQ--KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVR 109
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
I+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E F QI+
Sbjct: 110 IMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAKFRQIV 167
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
V Y H I+HRDLKAEN+LL G I KI DFG S K T G+P Y AP
Sbjct: 168 SAVQYCHQKYIVHRDLKAENLLLDGDMNI--KIADFGFSNEFTVGNKLDTFCGSPPYAAP 225
Query: 630 ELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
EL +G+ YD + D+W+LG +LY + + F+ + L L + + G
Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 272
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 132 bits (318), Expect = 2e-30
Identities = 82/227 (36%), Positives = 114/227 (50%), Gaps = 1/227 (0%)
Frame = +3
Query: 90 DLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVR 269
D Q N +L KTIGKG + V L + VK I Q + EVR
Sbjct: 52 DEQPHIGNYRLQ--KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVR 109
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
I+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E F QI+
Sbjct: 110 IMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAKFRQIV 167
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
V Y H I+HRDLKAEN+LL G I KI DFG S K T G+P Y AP
Sbjct: 168 SAVQYCHQKYIVHRDLKAENLLLDGDMNI--KIADFGFSNEFTVGNKLDTFCGSPPYAAP 225
Query: 630 ELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
EL +G+ YD + D+W+LG +LY + + F+ + L L + + G
Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 272
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 132 bits (318), Expect = 2e-30
Identities = 82/227 (36%), Positives = 114/227 (50%), Gaps = 1/227 (0%)
Frame = +3
Query: 90 DLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVR 269
D Q N +L KTIGKG + V L + VK I Q + EVR
Sbjct: 52 DEQPHIGNYRLQ--KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVR 109
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
I+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E F QI+
Sbjct: 110 IMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAKFRQIV 167
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
V Y H I+HRDLKAEN+LL G I KI DFG S K T G+P Y AP
Sbjct: 168 SAVQYCHQKYIVHRDLKAENLLLDGDMNI--KIADFGFSNEFTVGNKLDTFCGSPPYAAP 225
Query: 630 ELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
EL +G+ YD + D+W+LG +LY + + F+ + L L + + G
Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 272
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 132 bits (318), Expect = 2e-30
Identities = 82/227 (36%), Positives = 114/227 (50%), Gaps = 1/227 (0%)
Frame = +3
Query: 90 DLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVR 269
D Q N +L KTIGKG + V L + VK I Q + EVR
Sbjct: 52 DEQPHIGNYRLQ--KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVR 109
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
I+ + HPNI+ ++ E + + MEYA+ G + F YL +K++E F QI+
Sbjct: 110 IMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEV--FDYLVAHGRMKEKEARAKFRQIV 167
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
V Y H I+HRDLKAEN+LL G I KI DFG S K T G+P Y AP
Sbjct: 168 SAVQYCHQKYIVHRDLKAENLLLDGDMNI--KIADFGFSNEFTVGNKLDTFCGSPPYAAP 225
Query: 630 ELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
EL +G+ YD + D+W+LG +LY + + F+ + L L + + G
Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 272
>Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase 1
protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein.
Length = 326
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 131 bits (317), Expect = 3e-30
Identities = 77/215 (35%), Positives = 111/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 179 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 271
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 131 bits (317), Expect = 3e-30
Identities = 77/215 (35%), Positives = 111/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 179 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 271
>AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase
protein.
Length = 384
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 variant protein.
Length = 445
Score = 131 bits (317), Expect = 3e-30
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQD 815
Y+ KSDIW+LGCLLYE+C F + + L I G I Y + +
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIP-YRYSDELNE 246
Query: 816 LIDSMLSILPNKGRPS 863
+I ML+ L + RPS
Sbjct: 247 IITRMLN-LKDYHRPS 261
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 131 bits (317), Expect = 3e-30
Identities = 77/215 (35%), Positives = 111/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 179 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 271
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 131 bits (317), Expect = 3e-30
Identities = 77/215 (35%), Positives = 111/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 62 LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 121
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 122 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 179
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 180 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 237
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 238 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 272
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 130 bits (315), Expect = 5e-30
Identities = 83/250 (33%), Positives = 133/250 (53%), Gaps = 2/250 (0%)
Frame = +3
Query: 96 QNRFTNQKLSILKTIGKGTYGNVYLCENHEN--HLLTIVKDIQLNAKIQQHEQDIANEVR 269
QN ++ + L+T+G G++G V L + E H + + Q K++Q E I NE R
Sbjct: 45 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKR 103
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
IL + P ++ F Y+ + MEY G + F L+ + FY Q++
Sbjct: 104 ILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVV 161
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
L V Y+H+LD+IHRDLK EN+L+ + G + ++ DFG +K + +T T+ GTP YLAP
Sbjct: 162 LAVQYLHSLDLIHRDLKPENLLID-QQGYL-QVTDFGFAKRVKG--RTWTLCGTPEYLAP 217
Query: 630 ELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXM 809
E+ + Y+ D WALG L+YEM F ++ + + + I SG V + D +
Sbjct: 218 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD--L 275
Query: 810 QDLIDSMLSI 839
+DL+ S+L +
Sbjct: 276 KDLLRSLLQV 285
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 130 bits (314), Expect = 7e-30
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+LKTIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H I+
Sbjct: 118 LFEVIETEKTLYLIMEYASGGEV--FDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 176 HRDLKAENLLLDADMNI--KIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
D+W+LG +LY + + F+ + L L + + G
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 268
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 130 bits (314), Expect = 7e-30
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+LKTIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H I+
Sbjct: 118 LFEVIETEKTLYLIMEYASGGEV--FDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 176 HRDLKAENLLLDADMNI--KIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
D+W+LG +LY + + F+ + L L + + G
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 268
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 130 bits (314), Expect = 7e-30
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+LKTIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H I+
Sbjct: 118 LFEVIETEKTLYLIMEYASGGKV--FDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 176 HRDLKAENLLLDADMNI--KIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
D+W+LG +LY + + F+ + L L + + G
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 268
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 130 bits (314), Expect = 7e-30
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+LKTIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H I+
Sbjct: 118 LFEVIETEKTLYLIMEYASGGEV--FDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 176 HRDLKAENLLLDADMNI--KIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
D+W+LG +LY + + F+ + L L + + G
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 268
>AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein.
Length = 302
Score = 130 bits (314), Expect = 7e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQL-NAKIQQHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + + +K +Q+ + + D E+ +L + HPN+I
Sbjct: 36 IEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVI 95
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y F ++ + I +E A G+L+ + + + ++I + + YF Q+ + ++H+
Sbjct: 96 KYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSR 155
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 156 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGY 213
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L K I P+ Y ++ L++
Sbjct: 214 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNM 273
Query: 828 MLSILPNKGRP 860
++ P K RP
Sbjct: 274 CINPDPEK-RP 283
>CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 40 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 99
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 100 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 159
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 160 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 217
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 218 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 277
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 278 CICPDPHQ-RP 287
>BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 81 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 140
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 141 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 200
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 201 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 258
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 259 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 318
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 319 CICPDPHQ-RP 328
>AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 47 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 106
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 167 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 224
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 225 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 284
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 285 CICPDPHQ-RP 294
>AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 81 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 140
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 141 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 200
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 201 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 258
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 259 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 318
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 319 CICPDPHQ-RP 328
>AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6
protein.
Length = 338
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 72 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 131
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 132 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 191
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 192 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 249
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 250 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 309
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 310 CICPDPHQ-RP 319
>AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-1512
protein.
Length = 306
Score = 130 bits (313), Expect = 9e-30
Identities = 73/251 (29%), Positives = 132/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQ-QHEQDIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + QD E+ +L + HPNII
Sbjct: 40 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNII 99
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 100 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 159
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 160 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 217
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 218 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 277
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 278 CICPDPHQ-RP 287
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 129 bits (312), Expect = 1e-29
Identities = 85/261 (32%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLY 797
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+ D V
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV-- 352
Query: 798 DRXMQDLIDSMLSILPNKGRP 860
+DLI +L P++ RP
Sbjct: 353 TEGARDLISRLLKHNPSQ-RP 372
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 129 bits (312), Expect = 1e-29
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 179 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 271
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 129 bits (312), Expect = 1e-29
Identities = 77/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ E + + MEYA+ G + F YL +K++E F QI+ V Y H +I+
Sbjct: 121 LFEVIETEKTLYLVMEYASAGEV--FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL + I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 179 HRDLKAENLLLDAEANI--KIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + + F+ L L + + G
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRG 271
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 129 bits (311), Expect = 2e-29
Identities = 76/215 (35%), Positives = 110/215 (51%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+LKTIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
++ + + + MEYA+ G + F YL +K++E F QI+ V Y H I+
Sbjct: 118 LFEVIETQKTLYLIMEYASGGKV--FDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLKAEN+LL I KI DFG S K T G+P Y APEL +G+ YD +
Sbjct: 176 HRDLKAENLLLDADMNI--KIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
D+W+LG +LY + + F+ + L L + + G
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 268
>AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens
cDNA FLJ31216 fis, clone KIDNE2004084, moderately
similar to Morone saxatilis myosin heavy chain FM3A
(FM3A) mRNA. ).
Length = 1113
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 38 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 94
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 95 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 154
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 155 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 212
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 213 ACEQQYDSSYDARCDVWSLGITAIEL 238
>AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant
MYO3B.5 protein.
Length = 1192
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant
MYO3B.4 protein.
Length = 1275
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant
MYO3B.3 protein.
Length = 1314
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant
MYO3B.2 protein.
Length = 1341
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant
MYO3B.1 protein.
Length = 1251
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein.
Length = 1278
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein.
Length = 249
Score = 129 bits (311), Expect = 2e-29
Identities = 77/206 (37%), Positives = 117/206 (56%), Gaps = 14/206 (6%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM-KHPNII 302
I++TIGKGTYG VY N + L VK + + +++I E IL + HPN++
Sbjct: 29 IIETIGKGTYGKVYKVTNKRDGSLAAVKILD---PVSDMDEEIEAEYNILQFLPNHPNVV 85
Query: 303 SFYQCFYAEDYVM-----ISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVS 461
FY FY D+ + + +E G++ E + LRC Q + + I + LLG+
Sbjct: 86 KFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQ 145
Query: 462 YIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPEL- 635
++HN IIHRD+K NILLT + G VK+ DFG+S L S + + +T +GTP+++APE+
Sbjct: 146 HLHNNRIIHRDVKGNNILLTTEGG--VKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI 203
Query: 636 -CEGQ---PYDTKSDIWALGCLLYEM 701
CE Q YD + D+W+LG E+
Sbjct: 204 ACEQQYDSSYDARCDVWSLGITAIEL 229
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 128 bits (308), Expect = 4e-29
Identities = 85/248 (34%), Positives = 133/248 (53%), Gaps = 3/248 (1%)
Frame = +3
Query: 105 FTNQKLSILKTIGKGTYGNVYLC-ENHENHLLTI-VKDIQLNAKIQQHEQDIANEVRILS 278
++ Q L T+G GT+G V+L E H + V I +++Q EQ + NE +L
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQ-EQHVHNEKSVLK 102
Query: 279 TMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGV 458
+ HP +I + ++ E ++ + MEY G L F YLR LFY +I+ +
Sbjct: 103 EVSHPFLIRLFWTWHDERFLYMLMEYVPGGEL--FSYLRNRGRFSSTTGLFYSAEIICAI 160
Query: 459 SYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC 638
Y+H+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+
Sbjct: 161 EYLHSKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVI 216
Query: 639 EGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV-HPIDLVLYDRXMQD 815
+ + + D WALG L++EM + F + G+ + I +G + P L D ++D
Sbjct: 217 QSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHL---DFHVKD 273
Query: 816 LIDSMLSI 839
LI +L +
Sbjct: 274 LIKKLLVV 281
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 4e-29
Identities = 78/228 (34%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 96 QNRFTNQKLSILKTIGKGTYGNVYLCENHEN--HLLTIVKDIQLNAKIQQHEQDIANEVR 269
QN ++ + L+T+G G++G V L + E H + + Q K++Q E I NE R
Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKR 94
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
IL + P ++ F Y+ + MEY G + F L+ + FY Q++
Sbjct: 95 ILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVV 152
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
L V Y+H+LD+IHRDLK EN+L+ + G + ++ DFG +K + +T T+ GTP YLAP
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLID-QQGYL-QVTDFGFAKRVKG--RTWTLCGTPEYLAP 208
Query: 630 ELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
E+ + Y+ D WALG L+YEM F ++ + + + I SG V
Sbjct: 209 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRV 256
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 128 bits (308), Expect = 4e-29
Identities = 85/248 (34%), Positives = 133/248 (53%), Gaps = 3/248 (1%)
Frame = +3
Query: 105 FTNQKLSILKTIGKGTYGNVYLC-ENHENHLLTI-VKDIQLNAKIQQHEQDIANEVRILS 278
++ Q L T+G GT+G V+L E H + V I +++Q EQ + NE +L
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQ-EQHVHNEKSVLK 102
Query: 279 TMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGV 458
+ HP +I + ++ E ++ + MEY G L F YLR LFY +I+ +
Sbjct: 103 EVSHPFLIRLFWTWHDERFLYMLMEYVPGGEL--FSYLRNRGRFSSTTGLFYSAEIICAI 160
Query: 459 SYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC 638
Y+H+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+
Sbjct: 161 EYLHSKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVI 216
Query: 639 EGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV-HPIDLVLYDRXMQD 815
+ + + D WALG L++EM + F + G+ + I +G + P L D ++D
Sbjct: 217 QSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHL---DFHVKD 273
Query: 816 LIDSMLSI 839
LI +L +
Sbjct: 274 LIKKLLVV 281
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 4e-29
Identities = 78/228 (34%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 96 QNRFTNQKLSILKTIGKGTYGNVYLCENHEN--HLLTIVKDIQLNAKIQQHEQDIANEVR 269
QN ++ + L+T+G G++G V L + E H + + Q K++Q E I NE R
Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKR 94
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
IL + P ++ F Y+ + MEY G + F L+ + FY Q++
Sbjct: 95 ILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVV 152
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
L V Y+H+LD+IHRDLK EN+L+ + G + ++ DFG +K + +T T+ GTP YLAP
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLID-QQGYL-QVTDFGFAKRVKG--RTWTLCGTPEYLAP 208
Query: 630 ELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
E+ + Y+ D WALG L+YEM F ++ + + + I SG V
Sbjct: 209 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRV 256
>AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 128 bits (308), Expect = 4e-29
Identities = 72/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 133 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 190
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 191 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 249
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI DFG SK LA T T GT Y+APE+ + P Y +D
Sbjct: 250 KGDNVLV-NTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 308
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 309 IWSLGCTIIEMATSKPPF 326
>AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 128 bits (308), Expect = 4e-29
Identities = 72/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 93 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 150
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 151 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 209
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI DFG SK LA T T GT Y+APE+ + P Y +D
Sbjct: 210 KGDNVLV-NTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 268
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 269 IWSLGCTIIEMATSKPPF 286
>AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 128 bits (308), Expect = 4e-29
Identities = 72/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 133 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 190
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 191 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 249
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI DFG SK LA T T GT Y+APE+ + P Y +D
Sbjct: 250 KGDNVLV-NTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 308
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 309 IWSLGCTIIEMATSKPPF 326
>AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 128 bits (308), Expect = 4e-29
Identities = 72/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 93 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 150
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 151 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 209
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI DFG SK LA T T GT Y+APE+ + P Y +D
Sbjct: 210 KGDNVLV-NTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 268
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 269 IWSLGCTIIEMATSKPPF 286
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 4e-29
Identities = 78/228 (34%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 96 QNRFTNQKLSILKTIGKGTYGNVYLCENHEN--HLLTIVKDIQLNAKIQQHEQDIANEVR 269
QN ++ + L+T+G G++G V L + E H + + Q K++Q E I NE R
Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKR 94
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
IL + P ++ F Y+ + MEY G + F L+ + FY Q++
Sbjct: 95 ILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVV 152
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
L V Y+H+LD+IHRDLK EN+L+ + G + ++ DFG +K + +T T+ GTP YLAP
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLID-QQGYL-QVTDFGFAKRVKG--RTWTLCGTPEYLAP 208
Query: 630 ELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
E+ + Y+ D WALG L+YEM F ++ + + + I SG V
Sbjct: 209 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRV 256
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 128 bits (308), Expect = 4e-29
Identities = 76/228 (33%), Positives = 123/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 84 EMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIA 257
E + ++ + I + +GKG +GNVYL ++ + +K + A++++ E +
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLR 179
Query: 258 NEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYF 437
EV I S ++HPNI+ Y F+ V + +EYA G + + L+ ++ Y
Sbjct: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTATYI 237
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPY 617
++ +SY H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLD 294
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAIT 761
YL PE+ EG+ +D K D+W+LG L YE K FE+ T K I+
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
>AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens
cDNA FLJ16518 fis, clone NT2RI3007443, moderately
similar to MITOGEN-ACTIVATED PROTEIN KINASE KINASE
KINASE 5 (EC ).
Length = 748
Score = 128 bits (308), Expect = 4e-29
Identities = 72/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 93 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 150
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 151 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 209
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI DFG SK LA T T GT Y+APE+ + P Y +D
Sbjct: 210 KGDNVLV-NTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 268
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 269 IWSLGCTIIEMATSKPPF 286
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 128 bits (308), Expect = 4e-29
Identities = 78/228 (34%), Positives = 122/228 (53%), Gaps = 2/228 (0%)
Frame = +3
Query: 96 QNRFTNQKLSILKTIGKGTYGNVYLCENHEN--HLLTIVKDIQLNAKIQQHEQDIANEVR 269
QN ++ + L+T+G G++G V L + E H + + Q K++Q E I NE R
Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKR 94
Query: 270 ILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
IL + P ++ F Y+ + MEY G + F L+ + FY Q++
Sbjct: 95 ILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVV 152
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAP 629
L V Y+H+LD+IHRDLK EN+L+ + G + ++ DFG +K + +T T+ GTP YLAP
Sbjct: 153 LAVQYLHSLDLIHRDLKPENLLID-QQGYL-QVTDFGFAKRVKG--RTWTLCGTPEYLAP 208
Query: 630 ELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
E+ + Y+ D WALG L+YEM F ++ + + + I SG V
Sbjct: 209 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRV 256
>CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 127 bits (307), Expect = 5e-29
Identities = 72/251 (28%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQ-DIANEVRILSTMKHPNII 302
I K IG+G + VY + +K +Q+ + + D E+ +L + HPNII
Sbjct: 40 IEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARWDCVKEIGLLKQLNHPNII 99
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFM--YLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+ F ++ + I +E A G+L++ + + + ++I + + YF Q+ V ++H+
Sbjct: 100 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 159
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTS-TVIGTPYYLAPELCEGQPY 653
++HRD+K N+ +T +VK+GD G+ + +S + +++GTPYY++PE Y
Sbjct: 160 RVMHRDIKPANVFITATG--VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGY 217
Query: 654 DTKSDIWALGCLLYEMCTHKRAF--ESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+ KSDIW+LGCLLYEM + F + L L + I P+ Y +++L+
Sbjct: 218 NFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSM 277
Query: 828 MLSILPNKGRP 860
+ P++ RP
Sbjct: 278 CICPDPHQ-RP 287
>U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase
kinase kinase 5 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulating
kinase 1 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 804 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 863 DIWSLGCTIIEMATGKPPF 881
>AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 variant protein.
Length = 1455
Score = 127 bits (306), Expect = 6e-29
Identities = 71/199 (35%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 766 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 823
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRC-PQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F ++ I ME G+L+ + + P ++ I FY QIL G+ Y+H+ I+HRD
Sbjct: 824 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 883
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKS 665
+K +N+L+ Y ++KI DFG SK LA T T GT Y+APE+ + P Y +
Sbjct: 884 IKGDNVLI-NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 942
Query: 666 DIWALGCLLYEMCTHKRAF 722
DIW+LGC + EM T K F
Sbjct: 943 DIWSLGCTIIEMATGKPPF 961
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 126 bits (304), Expect = 1e-28
Identities = 85/260 (32%), Positives = 134/260 (51%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHE--NHLLTIVKDIQLNAKIQQH 242
F E QN + +KT+G G++G V L ++ E NH + D Q K++Q
Sbjct: 27 FLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID-QQGYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 126 bits (304), Expect = 1e-28
Identities = 84/251 (33%), Positives = 132/251 (52%), Gaps = 2/251 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMK 287
+ I + +GKG +GNVYL ++ + +K + A++++ E + EV I S ++
Sbjct: 130 EDFEIGRPLGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLRREVEIQSHLR 188
Query: 288 HPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYI 467
HPNI+ Y F+ V + +EYA G + + L+ ++ + +I +SY
Sbjct: 189 HPNILRLYGYFHDATRVYLILEYAPLGTV--YRELQKLSKFDEQRTANLYNRIANALSYC 246
Query: 468 HNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQ 647
H+ +IHRD+K EN+LL G G + KI DFG S S+++T T+ GT YL PE+ EG+
Sbjct: 247 HSKRVIHRDIKPENLLL-GSAGEL-KIADFGWSVHAPSSRRT-TLCGTLDYLPPEMIEGR 303
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
+D K D+W+LG L YE K FE+ T K I+ D V +DLI
Sbjct: 304 MHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFV--TEGARDLISR 361
Query: 828 MLSILPNKGRP 860
+L P++ RP
Sbjct: 362 LLKHNPSQ-RP 371
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (304), Expect = 1e-28
Identities = 85/260 (32%), Positives = 134/260 (51%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHE--NHLLTIVKDIQLNAKIQQH 242
F E QN + +KT+G G++G V L ++ E NH + D Q K++Q
Sbjct: 27 FLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID-QQGYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (304), Expect = 1e-28
Identities = 85/260 (32%), Positives = 134/260 (51%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHE--NHLLTIVKDIQLNAKIQQH 242
F E QN + +KT+G G++G V L ++ E NH + D Q K++Q
Sbjct: 27 FLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID-QQGYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 126 bits (304), Expect = 1e-28
Identities = 84/256 (32%), Positives = 132/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 3 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 61
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 62 AHLQHPNILRLYNYFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEELADA 119
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S S ++ T+ GT YL PE+
Sbjct: 120 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWSVHTPSLRR-KTMCGTLDYLPPEM 176
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 177 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 233
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 234 DLISRLLRYQPLERLP 249
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (304), Expect = 1e-28
Identities = 85/260 (32%), Positives = 134/260 (51%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHE--NHLLTIVKDIQLNAKIQQH 242
F E QN + +KT+G G++G V L ++ E NH + D Q K++Q
Sbjct: 27 FLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID-QQGYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 126 bits (304), Expect = 1e-28
Identities = 84/256 (32%), Positives = 132/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 34 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 92
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 93 AHLQHPNILRLYNYFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEELADA 150
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S S ++ T+ GT YL PE+
Sbjct: 151 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWSVHTPSLRR-KTMCGTLDYLPPEM 207
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 208 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 264
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 265 DLISRLLRYQPLERLP 280
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 126 bits (304), Expect = 1e-28
Identities = 84/256 (32%), Positives = 132/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 18 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 76
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 77 AHLQHPNILRLYNYFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEELADA 134
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S S ++ T+ GT YL PE+
Sbjct: 135 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWSVHTPSLRR-KTMCGTLDYLPPEM 191
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 192 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 248
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 249 DLISRLLRYQPLERLP 264
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 126 bits (304), Expect = 1e-28
Identities = 84/256 (32%), Positives = 132/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 37 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 95
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 96 AHLQHPNILRLYNYFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEELADA 153
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S S ++ T+ GT YL PE+
Sbjct: 154 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWSVHTPSLRR-KTMCGTLDYLPPEM 210
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 211 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 267
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 268 DLISRLLRYQPLERLP 283
>BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein.
Length = 214
Score = 126 bits (303), Expect = 1e-28
Identities = 69/203 (33%), Positives = 108/203 (53%), Gaps = 10/203 (4%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L TIG G+YG + + + K++ + + +Q + +EV +L +KHPNI+
Sbjct: 10 VLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVR 69
Query: 306 FYQCFY--AEDYVMISMEYATCGNLAEFMY--LRCPQVIKQEEILFYFCQILLGVSYIHN 473
+Y + I MEY G+LA + + Q + +E +L Q+ L + H
Sbjct: 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHR 129
Query: 474 LD-----IIHRDLKAENILLTGKYGIIVKIGDFGISKMLA-SAKKTSTVIGTPYYLAPEL 635
++HRDLK N+ L GK VK+GDFG++++L T +GTPYY++PE
Sbjct: 130 RSDGGHTVLHRDLKPANVFLDGKQN--VKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQ 187
Query: 636 CEGQPYDTKSDIWALGCLLYEMC 704
Y+ KSDIW+LGCLLYE+C
Sbjct: 188 MNRMSYNEKSDIWSLGCLLYELC 210
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 126 bits (303), Expect = 1e-28
Identities = 84/256 (32%), Positives = 132/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 37 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 95
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 96 AHLQHPNILRLYNHFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEELADA 153
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S S ++ T+ GT YL PE+
Sbjct: 154 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWSVHTPSLRR-KTMCGTLDYLPPEM 210
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 211 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 267
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 268 DLISRLLRYQPLERLP 283
>AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ16645 fis, clone TESTI4031745, moderately
similar to Mitogen-activated protein kinase kinase
kinase 5 (EC ).
Length = 788
Score = 125 bits (302), Expect = 2e-28
Identities = 71/198 (35%), Positives = 106/198 (53%), Gaps = 3/198 (1%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
+GKGTYG VY + N + +K+I + ++ Q + E+ + +KH NI+ +
Sbjct: 133 LGKGTYGIVYAGRDLSNQVRIAIKEIP--ERDSRYSQPLHEEIALHKYLKHRNIVQYLGS 190
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
Y+ I ME G+L+ + + + K+ I FY QIL G+ Y+H I+HRD+
Sbjct: 191 VSENGYIKIFMEQVPGGSLSALLRSKWGPM-KEPTIKFYTKQILEGLKYLHENQIVHRDI 249
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTPYYLAPELCEGQP--YDTKSD 668
K +N+L+ Y +VKI D G SK LA T T GT Y+APE+ + P Y +D
Sbjct: 250 KGDNVLV-NTYSGVVKISDLGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPAD 308
Query: 669 IWALGCLLYEMCTHKRAF 722
IW+LGC + EM T K F
Sbjct: 309 IWSLGCTIIEMATSKPPF 326
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 125 bits (301), Expect = 3e-28
Identities = 76/247 (30%), Positives = 131/247 (53%), Gaps = 3/247 (1%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILSTMKHPNIISF 308
K +GKG + Y + N+ + K I + + H+++ I E+ + + H +++ F
Sbjct: 86 KVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQF 145
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++ + I +EY + ++A + R +V+ + E+ +Y QI+ G+ Y+H +I+H
Sbjct: 146 YHYFEDKENIYILLEYCSRRSMAHILKAR--KVLTEPEVRYYLRQIVSGLKYLHEQEILH 203
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPELCEGQPYDTKS 665
RDLK N + + +K+GDFG++ L + + T+ GTP YL+PE+ Q + +S
Sbjct: 204 RDLKLGNFFINE--AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCES 261
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS-VHPIDLVLYDRXMQDLIDSMLSIL 842
DIWALGC++Y M + FE+ L + I P L+ + LI SMLS
Sbjct: 262 DIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLL---APAKHLIASMLSKN 318
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 319 P-EDRPS 324
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 125 bits (301), Expect = 3e-28
Identities = 76/247 (30%), Positives = 131/247 (53%), Gaps = 3/247 (1%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILSTMKHPNIISF 308
K +GKG + Y + N+ + K I + + H+++ I E+ + + H +++ F
Sbjct: 79 KVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQF 138
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++ + I +EY + ++A + R +V+ + E+ +Y QI+ G+ Y+H +I+H
Sbjct: 139 YHYFEDKENIYILLEYCSRRSMAHILKAR--KVLTEPEVRYYLRQIVSGLKYLHEQEILH 196
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPELCEGQPYDTKS 665
RDLK N + + +K+GDFG++ L + + T+ GTP YL+PE+ Q + +S
Sbjct: 197 RDLKLGNFFINE--AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCES 254
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS-VHPIDLVLYDRXMQDLIDSMLSIL 842
DIWALGC++Y M + FE+ L + I P L+ + LI SMLS
Sbjct: 255 DIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLL---APAKHLIASMLSKN 311
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 312 P-EDRPS 317
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 125 bits (301), Expect = 3e-28
Identities = 76/247 (30%), Positives = 131/247 (53%), Gaps = 3/247 (1%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILSTMKHPNIISF 308
K +GKG + Y + N+ + K I + + H+++ I E+ + + H +++ F
Sbjct: 86 KVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQF 145
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++ + I +EY + ++A + R +V+ + E+ +Y QI+ G+ Y+H +I+H
Sbjct: 146 YHYFEDKENIYILLEYCSRRSMAHILKAR--KVLTEPEVRYYLRQIVSGLKYLHEQEILH 203
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPELCEGQPYDTKS 665
RDLK N + + +K+GDFG++ L + + T+ GTP YL+PE+ Q + +S
Sbjct: 204 RDLKLGNFFINE--AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCES 261
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS-VHPIDLVLYDRXMQDLIDSMLSIL 842
DIWALGC++Y M + FE+ L + I P L+ + LI SMLS
Sbjct: 262 DIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLL---APAKHLIASMLSKN 318
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 319 P-EDRPS 324
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 125 bits (301), Expect = 3e-28
Identities = 76/247 (30%), Positives = 131/247 (53%), Gaps = 3/247 (1%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILSTMKHPNIISF 308
K +GKG + Y + N+ + K I + + H+++ I E+ + + H +++ F
Sbjct: 86 KVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQF 145
Query: 309 YQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIH 488
Y F ++ + I +EY + ++A + R +V+ + E+ +Y QI+ G+ Y+H +I+H
Sbjct: 146 YHYFEDKENIYILLEYCSRRSMAHILKAR--KVLTEPEVRYYLRQIVSGLKYLHEQEILH 203
Query: 489 RDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPYYLAPELCEGQPYDTKS 665
RDLK N + + +K+GDFG++ L + + T+ GTP YL+PE+ Q + +S
Sbjct: 204 RDLKLGNFFINE--AMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCES 261
Query: 666 DIWALGCLLYEMCTHKRAFESETLVGLVKAITSGS-VHPIDLVLYDRXMQDLIDSMLSIL 842
DIWALGC++Y M + FE+ L + I P L+ + LI SMLS
Sbjct: 262 DIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLL---APAKHLIASMLSKN 318
Query: 843 PNKGRPS 863
P + RPS
Sbjct: 319 P-EDRPS 324
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 125 bits (301), Expect = 3e-28
Identities = 67/206 (32%), Positives = 111/206 (53%), Gaps = 7/206 (3%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
IG G + V+ + E H L + + + + + E++IL +KH NI++ Y
Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDF 81
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
+ V + MEY G+LA+ YL + + ++ I + QI + +H+ IIHRDL
Sbjct: 82 QEMANSVYLVMEYCNGGDLAD--YLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDL 139
Query: 498 KAENILLTGKYG-------IIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD 656
K +NILL+ G I VKI DFG ++ L S +T+ G+P Y+APE+ Q YD
Sbjct: 140 KPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYD 199
Query: 657 TKSDIWALGCLLYEMCTHKRAFESET 734
K+D+W++G ++Y+ T K F++ +
Sbjct: 200 GKADLWSIGTIVYQCLTGKAPFQASS 225
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 125 bits (301), Expect = 3e-28
Identities = 67/206 (32%), Positives = 111/206 (53%), Gaps = 7/206 (3%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
IG G + V+ + E H L + + + + + E++IL +KH NI++ Y
Sbjct: 38 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDF 97
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
+ V + MEY G+LA+ YL + + ++ I + QI + +H+ IIHRDL
Sbjct: 98 QEMANSVYLVMEYCNGGDLAD--YLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDL 155
Query: 498 KAENILLTGKYG-------IIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD 656
K +NILL+ G I VKI DFG ++ L S +T+ G+P Y+APE+ Q YD
Sbjct: 156 KPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYD 215
Query: 657 TKSDIWALGCLLYEMCTHKRAFESET 734
K+D+W++G ++Y+ T K F++ +
Sbjct: 216 GKADLWSIGTIVYQCLTGKAPFQASS 241
>U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein.
Length = 626
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 366 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 425
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 426 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 483
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 484 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 541
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 542 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 581
>DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 variant 2 protein.
Length = 622
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 362 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 421
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 422 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 479
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 480 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 537
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 538 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 577
>BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 366 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 425
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 426 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 483
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 484 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 541
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 542 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 581
>BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 366 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 425
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 426 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 483
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 484 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 541
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 542 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 581
>BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 protein.
Length = 626
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 366 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 425
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 426 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 483
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 484 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 541
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 542 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 581
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 124 bits (300), Expect = 3e-28
Identities = 67/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K +L+ IG+G++G VY + + +K I + ++ +++ E+ I+ ++HP
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ F + V++ +YA G L F L + ++++ Q++ + Y+H+
Sbjct: 62 NIVHMLDSFETDKEVVVVTDYAE-GEL--FQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVI-GTPYYLAPELCEGQP 650
I+HRD+K +NILL GI K+ DFG ++ +++ T I GTP Y++PEL E +P
Sbjct: 119 HRILHRDMKPQNILLAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERP 176
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
YD +D+W++GC+LYE+ F + ++ LV I V
Sbjct: 177 YDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPV 217
>BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for
IMAGE:3506235) protein.
Length = 594
Score = 124 bits (300), Expect = 3e-28
Identities = 73/220 (33%), Positives = 119/220 (54%), Gaps = 10/220 (4%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILSTMKHPNII 302
K +G+G +G VYLC + + K +Q + + ++++ E+++L ++H I+
Sbjct: 334 KLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIV 393
Query: 303 SFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNL 476
+Y C AE + I MEY G++ + L+ + + Y QIL G+SY+H+
Sbjct: 394 QYYGCLRDRAEKTLTIFMEYMPGGSVKD--QLKAYGALTESVTRKYTRQILEGMSYLHSN 451
Query: 477 DIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYYLAPELCEG 644
I+HRD+K NIL VK+GDFG SK L + + T V GTPY+++PE+ G
Sbjct: 452 MIVHRDIKGANILRDSAGN--VKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG 509
Query: 645 QPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
+ Y K+D+W+LGC + EM T K + E E + + K T
Sbjct: 510 EGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT 549
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 124 bits (300), Expect = 3e-28
Identities = 67/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K +L+ IG+G++G VY + + +K I + ++ +++ E+ I+ ++HP
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ F + V++ +YA G L F L + ++++ Q++ + Y+H+
Sbjct: 62 NIVHMLDSFETDKEVVVVTDYAE-GEL--FQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVI-GTPYYLAPELCEGQP 650
I+HRD+K +NILL GI K+ DFG ++ +++ T I GTP Y++PEL E +P
Sbjct: 119 HRILHRDMKPQNILLAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERP 176
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
YD +D+W++GC+LYE+ F + ++ LV I V
Sbjct: 177 YDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPV 217
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 124 bits (300), Expect = 3e-28
Identities = 67/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHP 293
+K +L+ IG+G++G VY + + +K I + ++ +++ E+ I+ ++HP
Sbjct: 19 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 78
Query: 294 NIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHN 473
NI+ F + V++ +YA G L F L + ++++ Q++ + Y+H+
Sbjct: 79 NIVHMLDSFETDKEVVVVTDYAE-GEL--FQILEDDGKLPEDQVQAIAAQLVSALYYLHS 135
Query: 474 LDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVI-GTPYYLAPELCEGQP 650
I+HRD+K +NILL GI K+ DFG ++ +++ T I GTP Y++PEL E +P
Sbjct: 136 HRILHRDMKPQNILLAKGGGI--KLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERP 193
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSV 773
YD +D+W++GC+LYE+ F + ++ LV I V
Sbjct: 194 YDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPV 234
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 124 bits (299), Expect = 5e-28
Identities = 89/245 (36%), Positives = 125/245 (51%), Gaps = 5/245 (2%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVK-DIQLNAKIQQHEQD---IANEVRILSTMKHPNI 299
+TIGKG + V HL+T K I++ K Q E++ I EV+I+ + HP+I
Sbjct: 12 RTIGKGNFAVV----KRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHI 67
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I YQ E + + EYA+ G + F +L + ++E F QI+ V + H +
Sbjct: 68 IRLYQVMETERMIYLVTEYASGGEI--FDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN 125
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD- 656
I+HRDLKAEN+LL I KI DFG S + + T G+P Y APEL EG+ YD
Sbjct: 126 IVHRDLKAENLLLDANLNI--KIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDG 183
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
K DIW+LG +LY + F+ TL L + SG I + + LI ML
Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFR-IPFFM-STECEHLIRHMLV 241
Query: 837 ILPNK 851
+ PNK
Sbjct: 242 LDPNK 246
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 213 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 272
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 273 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 330
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 331 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 385
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 386 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 444
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 445 CLQKIP-QDRPTSE 457
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 124 bits (299), Expect = 5e-28
Identities = 83/256 (32%), Positives = 131/256 (51%), Gaps = 3/256 (1%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQH--EQDIANEVRIL 275
R T I + +GKG +GNVYL E+H + +K + ++I++ E + E+ I
Sbjct: 3 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALK-VLFKSQIEKEGLEHQLRREIEIQ 61
Query: 276 STMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLG 455
+ ++HPNI+ Y F+ V + +EYA G L + L+ + + ++ ++
Sbjct: 62 AHLQHPNILRLYNYFHDARRVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEEVADA 119
Query: 456 VSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPEL 635
++Y H+ +IHRD+K EN+LL G G VKI DFG S + + T+ GT YL PE+
Sbjct: 120 LTYCHDKKVIHRDIKPENLLL-GFRGE-VKIADFGWS-VHTPLPERKTMCGTLDYLPPEM 176
Query: 636 CEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-PIDLVLYDRXMQ 812
EG+ YD K D+W +G L YE+ FES + + I V P+ + L R
Sbjct: 177 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR--- 233
Query: 813 DLIDSMLSILPNKGRP 860
DLI +L P + P
Sbjct: 234 DLISRLLRYQPLERLP 249
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 124 bits (299), Expect = 5e-28
Identities = 89/245 (36%), Positives = 125/245 (51%), Gaps = 5/245 (2%)
Frame = +3
Query: 132 KTIGKGTYGNVYLCENHENHLLTIVK-DIQLNAKIQQHEQD---IANEVRILSTMKHPNI 299
+TIGKG + V HL+T K I++ K Q E++ I EV+I+ + HP+I
Sbjct: 120 RTIGKGNFAVV----KRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHI 175
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I YQ E + + EYA+ G + F +L + ++E F QI+ V + H +
Sbjct: 176 IRLYQVMETERMIYLVTEYASGGEI--FDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN 233
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD- 656
I+HRDLKAEN+LL I KI DFG S + + T G+P Y APEL EG+ YD
Sbjct: 234 IVHRDLKAENLLLDANLNI--KIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDG 291
Query: 657 TKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLS 836
K DIW+LG +LY + F+ TL L + SG I + + LI ML
Sbjct: 292 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFR-IPFFM-STECEHLIRHMLV 349
Query: 837 ILPNK 851
+ PNK
Sbjct: 350 LDPNK 354
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 124 bits (299), Expect = 5e-28
Identities = 79/254 (31%), Positives = 137/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 44 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 103
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 104 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 161
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY++APE+ EGQ
Sbjct: 162 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWMAPEVILAMDEGQ 216
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 217 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 275
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 276 CLQKIP-QDRPTSE 288
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 124 bits (298), Expect = 6e-28
Identities = 75/222 (33%), Positives = 120/222 (54%), Gaps = 1/222 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQ-HEQDIANEVRILSTMKH 290
Q L T+G GT+G V+L + +K + + I++ EQ + NE +L + H
Sbjct: 47 QDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH 106
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P +I + ++ E ++ + MEY G L F YLR LFY +I+ + Y+H
Sbjct: 107 PFLIRLFWTWHEERFLYMLMEYVPGGEL--FSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQP 650
+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+ + +
Sbjct: 165 SKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH 776
+ D WALG L++EM + F + G+ + I +G ++
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLY 262
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 124 bits (298), Expect = 6e-28
Identities = 75/222 (33%), Positives = 120/222 (54%), Gaps = 1/222 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQ-HEQDIANEVRILSTMKH 290
Q L T+G GT+G V+L + +K + + I++ EQ + NE +L + H
Sbjct: 47 QDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH 106
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P +I + ++ E ++ + MEY G L F YLR LFY +I+ + Y+H
Sbjct: 107 PFLIRLFWTWHEERFLYMLMEYVPGGEL--FSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQP 650
+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+ + +
Sbjct: 165 SKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH 776
+ D WALG L++EM + F + G+ + I +G ++
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLY 262
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 48 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 105
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 106 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 164
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 165 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 222
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 223 PYDYKADVWSLGITLIEM 240
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 124 bits (298), Expect = 6e-28
Identities = 75/222 (33%), Positives = 120/222 (54%), Gaps = 1/222 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQ-HEQDIANEVRILSTMKH 290
Q L T+G GT+G V+L + +K + + I++ EQ + NE +L + H
Sbjct: 47 QDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH 106
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P +I + ++ E ++ + MEY G L F YLR LFY +I+ + Y+H
Sbjct: 107 PFLIRLFWTWHEERFLYMLMEYVPGGEL--FSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQP 650
+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+ + +
Sbjct: 165 SKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH 776
+ D WALG L++EM + F + G+ + I +G ++
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLY 262
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 124 bits (298), Expect = 6e-28
Identities = 75/222 (33%), Positives = 120/222 (54%), Gaps = 1/222 (0%)
Frame = +3
Query: 114 QKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQ-HEQDIANEVRILSTMKH 290
Q L T+G GT+G V+L + +K + + I++ EQ + NE +L + H
Sbjct: 47 QDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH 106
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P +I + ++ E ++ + MEY G L F YLR LFY +I+ + Y+H
Sbjct: 107 PFLIRLFWTWHEERFLYMLMEYVPGGEL--FSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQP 650
+ +I++RDLK ENILL + G I K+ DFG +K L +T T+ GTP YLAPE+ + +
Sbjct: 165 SKEIVYRDLKPENILLD-RDGHI-KLTDFGFAKKLVD--RTWTLCGTPEYLAPEVIQSKG 220
Query: 651 YDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH 776
+ D WALG L++EM + F + G+ + I +G ++
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLY 262
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 124 bits (298), Expect = 6e-28
Identities = 72/198 (36%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I+ +G G +G VY +N E +L K I + K ++ +D E+ IL++ HPNI+
Sbjct: 36 IIGELGDGAFGKVYKAQNKETSVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVK 93
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
FY E+ + I +E+ G + + L + + + +I Q L ++Y+H+ II
Sbjct: 94 LLDAFYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKII 152
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE---GQ 647
HRDLKA NIL T I K+ DFG+S K + ++ + IGTPY++APE +CE +
Sbjct: 153 HRDLKAGNILFTLDGDI--KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDR 210
Query: 648 PYDTKSDIWALGCLLYEM 701
PYD K+D+W+LG L EM
Sbjct: 211 PYDYKADVWSLGITLIEM 228
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 255
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 256 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 314 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 372 TVDWWCLGAVLYEM 385
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 160
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 161 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 219 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 277 TVDWWCLGAVLYEM 290
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 123 bits (297), Expect = 8e-28
Identities = 86/287 (29%), Positives = 137/287 (47%), Gaps = 3/287 (1%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ESETLVGLVKAITSGSV-HPIDLVLYDRXMQDLIDSMLSILPNKGRP 860
ES + + I + P + + QDLI +L P++ P
Sbjct: 274 ESASHNETYRRIVKVDLKFPASVPM---GAQDLISKLLRHNPSERLP 317
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 160
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 161 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 219 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 277 TVDWWCLGAVLYEM 290
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 255
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 256 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 314 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 372 TVDWWCLGAVLYEM 385
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 255
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 256 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 314 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 372 TVDWWCLGAVLYEM 385
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 115 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 174
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 175 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 232
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 233 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 290
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 291 TVDWWCLGAVLYEM 304
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 160
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 161 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 219 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 277 TVDWWCLGAVLYEM 290
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 91 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 150
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 151 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 208
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 209 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 266
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 267 TVDWWCLGAVLYEM 280
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 160
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 161 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 219 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 277 TVDWWCLGAVLYEM 290
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 71/194 (36%), Positives = 107/194 (55%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRIL-STMKHPNII 302
LK IGKG++G V L + + VK +Q A +++ E+ I +E +L +KHP ++
Sbjct: 101 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLV 160
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F D + ++Y G L F +L+ + + FY +I + Y+H+L+I
Sbjct: 161 GLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL + I++ DFG+ K + TST GTP YLAPE+ QPYD
Sbjct: 219 VYRDLKPENILLDSQGHIVLT--DFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 277 TVDWWCLGAVLYEM 290
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 123 bits (296), Expect = 1e-27
Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 2/242 (0%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ES 728
ES
Sbjct: 274 ES 275
>BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 123 bits (296), Expect = 1e-27
Identities = 79/254 (31%), Positives = 136/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY+ APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWTAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 123 bits (296), Expect = 1e-27
Identities = 79/254 (31%), Positives = 136/254 (53%), Gaps = 5/254 (1%)
Frame = +3
Query: 123 SILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNI 299
S L+ IG G++G VY + N + +K + + K + QDI EVR L ++HPN
Sbjct: 29 SDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNT 88
Query: 300 ISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLD 479
I + C+ E + MEY G+ ++ + + + +++ EI L G++Y+H+ +
Sbjct: 89 IQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLHSHN 146
Query: 480 IIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC----EGQ 647
+IHRD+KA NILL+ + G +VK+GDFG + ++A A ++ +GTPY+ APE+ EGQ
Sbjct: 147 MIHRDVKAGNILLS-EPG-LVKLGDFGSASIMAPA---NSFVGTPYWTAPEVILAMDEGQ 201
Query: 648 PYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDS 827
YD K D+W+LG E+ K + + + I + + ++ +DS
Sbjct: 202 -YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDS 260
Query: 828 MLSILPNKGRPSKK 869
L +P + RP+ +
Sbjct: 261 CLQKIP-QDRPTSE 273
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 123 bits (296), Expect = 1e-27
Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 2/242 (0%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ES 728
ES
Sbjct: 274 ES 275
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 123 bits (296), Expect = 1e-27
Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 2/242 (0%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ES 728
ES
Sbjct: 274 ES 275
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 123 bits (296), Expect = 1e-27
Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 2/242 (0%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ES 728
ES
Sbjct: 274 ES 275
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 123 bits (296), Expect = 1e-27
Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 2/242 (0%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+ F
Sbjct: 215 KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Query: 723 ES 728
ES
Sbjct: 274 ES 275
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 122 bits (295), Expect = 1e-27
Identities = 73/215 (33%), Positives = 107/215 (49%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I +T+GKG + V L + +K I + + I EV+++ + HP+II
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIK 88
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
YQ +D + I E+A G + F YL + + E F QIL V Y H+ I+
Sbjct: 89 LYQVMETKDMLYIVTEFAKNGEM--FDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 146
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLK EN+LL G I K+ DFG S + ST G+P Y APE+ EG+ Y+ +
Sbjct: 147 HRDLKTENLLLDGNMDI--KLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQ 204
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + F+ L L + + G
Sbjct: 205 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 239
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 122 bits (295), Expect = 1e-27
Identities = 73/215 (33%), Positives = 107/215 (49%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I +T+GKG + V L + +K I + + I EV+++ + HP+II
Sbjct: 10 IERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIK 69
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
YQ +D + I E+A G + F YL + + E F QIL V Y H+ I+
Sbjct: 70 LYQVMETKDMLYIVTEFAKNGEM--FDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 127
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLK EN+LL G I K+ DFG S + ST G+P Y APE+ EG+ Y+ +
Sbjct: 128 HRDLKTENLLLDGNMDI--KLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQ 185
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + F+ L L + + G
Sbjct: 186 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 220
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 122 bits (295), Expect = 1e-27
Identities = 73/215 (33%), Positives = 107/215 (49%), Gaps = 1/215 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I +T+GKG + V L + +K I + + I EV+++ + HP+II
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIK 88
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
YQ +D + I E+A G + F YL + + E F QIL V Y H+ I+
Sbjct: 89 LYQVMETKDMLYIVTEFAKNGEM--FDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 146
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TK 662
HRDLK EN+LL G I K+ DFG S + ST G+P Y APE+ EG+ Y+ +
Sbjct: 147 HRDLKTENLLLDGNMDI--KLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQ 204
Query: 663 SDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
DIW+LG +LY + F+ L L + + G
Sbjct: 205 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 239
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 122 bits (293), Expect = 2e-27
Identities = 65/215 (30%), Positives = 118/215 (54%), Gaps = 1/215 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF 722
++APE+ + Y+ +DIW+LG EM KR +
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKRPY 224
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 121 bits (292), Expect = 3e-27
Identities = 78/243 (32%), Positives = 122/243 (50%), Gaps = 3/243 (1%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILL-GVSYIHNLDIIHRDLKAENILLTGKYGII 539
G L + ++ C ++ + + L + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGMLYKELHKTCTFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL 217
Query: 540 VKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRA 719
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+
Sbjct: 218 -KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPP 275
Query: 720 FES 728
FES
Sbjct: 276 FES 278
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 121 bits (292), Expect = 3e-27
Identities = 65/202 (32%), Positives = 110/202 (54%), Gaps = 2/202 (0%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNIISFYQ 314
+GKG++ VY E+ + L +K I A + Q + NEV+I +KHP+I+ Y
Sbjct: 18 LGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYN 77
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F +YV + +E G + ++ R + + E + QI+ G+ Y+H+ I+HRD
Sbjct: 78 YFEDSNYVYLVLEMCHNGEMNRYLKNRV-KPFSENEARHFMHQIITGMLYLHSHGILHRD 136
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKSDI 671
L N+LLT I KI DFG++ L +K T+ GTP Y++PE+ + +SD+
Sbjct: 137 LTLSNLLLTRNMNI--KIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDV 194
Query: 672 WALGCLLYEMCTHKRAFESETL 737
W+LGC+ Y + + F+++T+
Sbjct: 195 WSLGCMFYTLLIGRPPFDTDTV 216
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 121 bits (291), Expect = 4e-27
Identities = 65/202 (32%), Positives = 109/202 (53%), Gaps = 2/202 (0%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNIISFYQ 314
+GKG++ VY E+ L +K I A + Q + NEV+I +KHP+I+ Y
Sbjct: 18 LGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSILELYN 77
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F +YV + +E G + ++ R + + E + QI+ G+ Y+H+ I+HRD
Sbjct: 78 YFEDSNYVYLVLEMCHNGEMNRYLKNRV-KPFSENEARHFMHQIITGMLYLHSHGILHRD 136
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKSDI 671
L N+LLT I KI DFG++ L +K T+ GTP Y++PE+ + +SD+
Sbjct: 137 LTLSNLLLTRNMNI--KIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDV 194
Query: 672 WALGCLLYEMCTHKRAFESETL 737
W+LGC+ Y + + F+++T+
Sbjct: 195 WSLGCMFYTLLIGRPPFDTDTV 216
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 121 bits (291), Expect = 4e-27
Identities = 65/202 (32%), Positives = 109/202 (53%), Gaps = 2/202 (0%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHE-QDIANEVRILSTMKHPNIISFYQ 314
+GKG++ VY E+ L +K I A + Q + NEV+I +KHP+I+ Y
Sbjct: 18 LGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYN 77
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
F +YV + +E G + ++ R + + E + QI+ G+ Y+H+ I+HRD
Sbjct: 78 YFEDSNYVYLVLEMCHNGEMNRYLKNRV-KPFSENEARHFMHQIITGMLYLHSHGILHRD 136
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASA-KKTSTVIGTPYYLAPELCEGQPYDTKSDI 671
L N+LLT I KI DFG++ L +K T+ GTP Y++PE+ + +SD+
Sbjct: 137 LTLSNLLLTRNMNI--KIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDV 194
Query: 672 WALGCLLYEMCTHKRAFESETL 737
W+LGC+ Y + + F+++T+
Sbjct: 195 WSLGCMFYTLLIGRPPFDTDTV 216
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 121 bits (291), Expect = 4e-27
Identities = 87/288 (30%), Positives = 138/288 (47%), Gaps = 4/288 (1%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNR-FTNQKLSILKTIGKGTYGNVYLCENHE 185
S + PT P M +SG L R FT I + +GKG +GNVYL +
Sbjct: 69 SRSNVQPTAAPGQKVMEN---SSGTPDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKK 125
Query: 186 NHLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYA 359
+H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 126 SHFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYA 184
Query: 360 TCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGII 539
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 185 PRGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL 241
Query: 540 VKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRA 719
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+
Sbjct: 242 -KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPP 299
Query: 720 FESETLVGLVKAITSGSV-HPIDLVLYDRXMQDLIDSMLSILPNKGRP 860
FES + + I + P + + QDLI +L P++ P
Sbjct: 300 FESASHNETYRRIVKVDLKFPASVPM---GAQDLISKLLRHNPSERLP 344
>AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b
protein.
Length = 619
Score = 120 bits (290), Expect = 6e-27
Identities = 76/228 (33%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Frame = +3
Query: 108 TNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILS 278
TN +L K +G+G +G VYLC + + VK +Q + + +++ E+++L
Sbjct: 354 TNWRLG--KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLK 411
Query: 279 TMKHPNIISFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILL 452
+ H I+ +Y C E + I MEY G++ + L+ + + Y QIL
Sbjct: 412 NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKD--QLKAYGALTENVTRKYTRQILE 469
Query: 453 GVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYY 620
GV Y+H+ I+HRD+K NIL VK+GDFG SK L + + T V GTPY+
Sbjct: 470 GVHYLHSNMIVHRDIKGANILRDSTGN--VKLGDFGASKRLQTICLSGTGMKSVTGTPYW 527
Query: 621 LAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
++PE+ GQ Y K+DIW++ C + EM T K + E E + + K T
Sbjct: 528 MSPEVISGQGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIAT 575
>AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein.
Length = 968
Score = 120 bits (290), Expect = 6e-27
Identities = 71/203 (34%), Positives = 114/203 (56%), Gaps = 6/203 (2%)
Frame = +3
Query: 111 NQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKH 290
N+ I+ +G G +G VY +N E L K I+ K ++ +D E+ IL+T H
Sbjct: 33 NEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIE--TKSEEELEDYIVEIEILATCDH 90
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P I+ +Y + + I +E+ G + + L + + + +I Q+L ++++H
Sbjct: 91 PYIVKLLGAYYHDGKLWIMIEFCP-GGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLH 149
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE 641
+ IIHRDLKA N+L+T + I ++ DFG+S K L + +K + IGTPY++APE +CE
Sbjct: 150 SKRIIHRDLKAGNVLMTLEGDI--RLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCE 207
Query: 642 ---GQPYDTKSDIWALGCLLYEM 701
PYD K+DIW+LG L EM
Sbjct: 208 TMKDTPYDYKADIWSLGITLIEM 230
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 74 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 133
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 134 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 190
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 191 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 246
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 247 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 306
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 307 SH---FSSDLKDLLRNLLQV 323
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 74 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 133
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 134 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 190
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 191 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 246
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 247 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 306
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 307 SH---FSSDLKDLLRNLLQV 323
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 260 SH---FSSDLKDLLRNLLQV 276
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 120 bits (289), Expect = 7e-27
Identities = 77/243 (31%), Positives = 120/243 (49%), Gaps = 3/243 (1%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCP-QVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGII 539
G L + + C + + ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGMLYKELQKSCTFDEQRTATVRAVMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL 217
Query: 540 VKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRA 719
KI DFG S S ++ T+ GT YL PE+ EG+ ++ K D+W +G L YE+
Sbjct: 218 -KIADFGWSVHAPSLRR-KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPP 275
Query: 720 FES 728
FES
Sbjct: 276 FES 278
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 120 bits (289), Expect = 7e-27
Identities = 83/260 (31%), Positives = 132/260 (50%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 53 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 112
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 113 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 169
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 170 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 225
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 226 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 285
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ ++DL+ ++L +
Sbjct: 286 SH---FSSDLKDLLRNLLQV 302
>BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase 10
protein.
Length = 968
Score = 120 bits (288), Expect = 1e-26
Identities = 71/203 (34%), Positives = 114/203 (56%), Gaps = 6/203 (2%)
Frame = +3
Query: 111 NQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKH 290
N+ I+ +G G +G VY +N E L K I+ K ++ +D E+ IL+T H
Sbjct: 33 NEVWEIVGELGDGAFGKVYKAKNKETGALVAAKVIE--TKSEEELEDYIVEIEILATCDH 90
Query: 291 PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIH 470
P I+ +Y + + I +E+ G + + L + + + +I Q+L ++++H
Sbjct: 91 PYIVKLLGAYYHDGKLWIMIEFCP-GGAVDAIMLELDRGLTEPQIQEVCRQMLEALNFLH 149
Query: 471 NLDIIHRDLKAENILLTGKYGIIVKIGDFGIS-KMLASAKKTSTVIGTPYYLAPE--LCE 641
+ IIHRDLKA N+L+T + I ++ DFG+S K L + +K + IGTPY++APE +CE
Sbjct: 150 SKRIIHRDLKAGNVLMTLEGDI--RLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCE 207
Query: 642 ---GQPYDTKSDIWALGCLLYEM 701
PYD K+DIW+LG L EM
Sbjct: 208 TMKDTPYDYKADIWSLGITLIEM 230
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 92.3 bits (219), Expect(2) = 1e-26
Identities = 52/130 (40%), Positives = 71/130 (54%), Gaps = 1/130 (0%)
Frame = +3
Query: 381 FMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFG 560
F YL +K++E F QI+ V Y H +I+HRDLKAEN+LL + I KI DFG
Sbjct: 174 FDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANI--KIADFG 231
Query: 561 ISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TKSDIWALGCLLYEMCTHKRAFESETL 737
S K T G+P Y APEL +G+ YD + DIW+LG +LY + + F+ L
Sbjct: 232 FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNL 291
Query: 738 VGLVKAITSG 767
L + + G
Sbjct: 292 KELRERVLRG 301
Score = 48.4 bits (110), Expect(2) = 1e-26
Identities = 25/81 (30%), Positives = 39/81 (48%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
+L+TIGKG + V L + +K I Q + EVRI+ + HPNI+
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 120
Query: 306 FYQCFYAEDYVMISMEYATCG 368
++ E + + MEYA+ G
Sbjct: 121 LFEVIETEKTLYLVMEYASAG 141
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 119 bits (287), Expect = 1e-26
Identities = 72/216 (33%), Positives = 106/216 (49%), Gaps = 2/216 (0%)
Frame = +3
Query: 126 ILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIIS 305
I +T+GKG + V L + +K I + + I EV+++ + HP+II
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIK 88
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
YQ +D + I E+A G + F YL + + E F QIL V Y H+ I+
Sbjct: 89 LYQVMETKDMLYIVTEFAKNGEM--FDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 146
Query: 486 HRDLKAENILLTGKYGI-IVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-T 659
HRDLK EN+LL G I + DFG S + ST G+P Y APE+ EG+ Y+
Sbjct: 147 HRDLKTENLLLDGNMDIKLAGTEDFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 206
Query: 660 KSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
+ DIW+LG +LY + F+ L L + + G
Sbjct: 207 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 242
>AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ90523 fis, clone NT2RP4000634, highly similar to
Homo sapiens mitogen-activated protein kinase kinase
kinase ).
Length = 423
Score = 119 bits (287), Expect = 1e-26
Identities = 75/228 (32%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Frame = +3
Query: 108 TNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILS 278
TN +L K +G+G +G VYLC + + VK +Q + + +++ E+++L
Sbjct: 158 TNWRLG--KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLK 215
Query: 279 TMKHPNIISFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILL 452
+ H I+ +Y C E + I MEY G++ + L+ + + Y QIL
Sbjct: 216 NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKD--QLKAYGALTENVTRKYTRQILE 273
Query: 453 GVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYY 620
GV Y+H+ I+HRD+K NIL VK+GDFG SK L + + T V GTPY+
Sbjct: 274 GVHYLHSNMIVHRDIKGANILRDSTGN--VKLGDFGASKRLQTICLSGTGMKSVTGTPYW 331
Query: 621 LAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
++PE+ G+ Y K+DIW++ C + EM T K + E E + + K T
Sbjct: 332 MSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIAT 379
>AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated protein
kinase kinase kinase MEKK2 protein.
Length = 618
Score = 119 bits (287), Expect = 1e-26
Identities = 76/228 (33%), Positives = 118/228 (51%), Gaps = 10/228 (4%)
Frame = +3
Query: 108 TNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILS 278
TN +L K +G+G +G VYLC + + VK +Q + + +++ E+++L
Sbjct: 353 TNWRLG--KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLK 410
Query: 279 TMKHPNIISFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILL 452
H I+ +Y C E + I MEY G++ + L+ + + Y QIL
Sbjct: 411 NFLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKD--QLKAYGALTENGTRKYTRQILE 468
Query: 453 GVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYY 620
GV Y+H+ I+HRD+K NIL VK+GDFG SK L + + T V GTPY+
Sbjct: 469 GVHYLHSNMILHRDIKGANILRDSTGN--VKLGDFGASKRLQTICLSGTGMKSVTGTPYW 526
Query: 621 LAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
++PE+ GQ Y K+DIW++ C + EM T K + E E + + K T
Sbjct: 527 MSPEVISGQGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIAT 574
>AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein.
Length = 270
Score = 119 bits (287), Expect = 1e-26
Identities = 75/228 (32%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Frame = +3
Query: 108 TNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILS 278
TN +L K +G+G +G VYLC + + VK +Q + + +++ E+++L
Sbjct: 5 TNWRLG--KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLK 62
Query: 279 TMKHPNIISFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILL 452
+ H I+ +Y C E + I MEY G++ + L+ + + Y QIL
Sbjct: 63 NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKD--QLKAYGALTENVTRKYTRQILE 120
Query: 453 GVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYY 620
GV Y+H+ I+HRD+K NIL VK+GDFG SK L + + T V GTPY+
Sbjct: 121 GVHYLHSNMIVHRDIKGANILRDSTGN--VKLGDFGASKRLQTICLSGTGMKSVTGTPYW 178
Query: 621 LAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
++PE+ G+ Y K+DIW++ C + EM T K + E E + + K T
Sbjct: 179 MSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIAT 226
>AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b
variant protein.
Length = 621
Score = 119 bits (287), Expect = 1e-26
Identities = 75/228 (32%), Positives = 119/228 (52%), Gaps = 10/228 (4%)
Frame = +3
Query: 108 TNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN---EVRILS 278
TN +L K +G+G +G VYLC + + VK +Q + + +++ E+++L
Sbjct: 356 TNWRLG--KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLK 413
Query: 279 TMKHPNIISFYQCFY--AEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILL 452
+ H I+ +Y C E + I MEY G++ + L+ + + Y QIL
Sbjct: 414 NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKD--QLKAYGALTENVTRKYTRQILE 471
Query: 453 GVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTST----VIGTPYY 620
GV Y+H+ I+HRD+K NIL VK+GDFG SK L + + T V GTPY+
Sbjct: 472 GVHYLHSNMIVHRDIKGANILRDSTGN--VKLGDFGASKRLQTICLSGTGMKSVTGTPYW 529
Query: 621 LAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAIT 761
++PE+ G+ Y K+DIW++ C + EM T K + E E + + K T
Sbjct: 530 MSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIAT 577
>Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 97
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 98 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 155
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 AVDWWCLGAVLYEM 227
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 98 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 157
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 158 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 215
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 216 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 274 AVDWWCLGAVLYEM 287
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 97
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 98 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIDYLHSLNI 155
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 AVDWWCLGAVLYEM 227
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 97
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 98 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 155
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 AVDWWCLGAVLYEM 227
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 119 bits (286), Expect = 2e-26
Identities = 83/260 (31%), Positives = 133/260 (51%), Gaps = 3/260 (1%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+++LDII+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLNSLDIIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSGSVH-P 779
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG V P
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query: 780 IDLVLYDRXMQDLIDSMLSI 839
+ + ++DL+ ++L +
Sbjct: 260 SN---FSSDLKDLLRNLLQV 276
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 97
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 98 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 155
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 AVDWWCLGAVLYEM 227
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 64 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 123
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 124 GLRYSFQTPEELYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 181
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 182 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 239
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 240 AVDWWCLGAVLYEM 253
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 190 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 98 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 157
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 158 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 215
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 216 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 274 AVDWWCLGAVLYEM 287
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 119 bits (286), Expect = 2e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG YG V L + + VK +Q + +++ EQ +A +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLV 97
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+I
Sbjct: 98 GLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNI 155
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
I+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 IYRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 AVDWWCLGAVLYEM 227
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 119 bits (286), Expect = 2e-26
Identities = 64/212 (30%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 41 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 96
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 97 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 155
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 156 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 213
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
++APE+ + Y+ +DIW+LG EM K
Sbjct: 214 WMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 245
>Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 103/193 (53%), Gaps = 2/193 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRIL-STMKHPNIIS 305
LK IGKG YG V L + + VK +Q + +++ E I E +L ++HP ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKESHIMAERSVLLKNVRHPFLVG 97
Query: 306 FYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDII 485
F + + ++Y G L F +L+ + + FY ++ + Y+H+L+II
Sbjct: 98 LRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSLNII 155
Query: 486 HRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDTK 662
+RDLK ENILL + +++ DFG+ K + TST GTP YLAPE+ +PYD
Sbjct: 156 YRDLKPENILLDCQGHVVLT--DFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRA 213
Query: 663 SDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 214 VDWWCLGAVLYEM 226
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 118 bits (284), Expect = 3e-26
Identities = 68/194 (35%), Positives = 105/194 (54%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG++G V L + + VK +Q + + EQ +A +L +KHP ++
Sbjct: 98 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLV 157
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F + + +++ G L F +L+ + + FY +I + Y+H++ I
Sbjct: 158 GLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEHRARFYAAEIASALGYLHSIKI 215
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL G +V + DFG+ K +A + T+T GTP YLAPE+ QPYD
Sbjct: 216 VYRDLKPENILLDS-VGHVV-LTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 274 TVDWWCLGAVLYEM 287
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 118 bits (284), Expect = 3e-26
Identities = 69/215 (32%), Positives = 113/215 (52%), Gaps = 5/215 (2%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILS 278
+F Q +G+G +G V L E + + +K ++ + + E D + E RI
Sbjct: 603 QFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE 662
Query: 279 TM---KHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
T+ +HP +++ + CF +++V MEYA G+L M++ V + +FY ++
Sbjct: 663 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHT-DVFSEPRAVFYAACVV 719
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLA 626
LG+ Y+H I++RDLK +N+LL + +VKI DFG+ K + +TST GTP +LA
Sbjct: 720 LGLQYLHEHKIVYRDLKLDNLLLDTEG--LVKIADFGLCKEGMGYGDRTSTFCGTPEFLA 777
Query: 627 PELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESE 731
PE+ Y D W LG L+YEM + F +
Sbjct: 778 PEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGD 812
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 118 bits (284), Expect = 3e-26
Identities = 80/240 (33%), Positives = 116/240 (48%), Gaps = 1/240 (0%)
Frame = +3
Query: 135 TIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQ 314
T+GKG + V L + +K I + + + I EV+I+ + HP+II YQ
Sbjct: 25 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQ 84
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
+ + + EYA G + F YL + + E F QIL V Y H I+HRD
Sbjct: 85 VMETKSMLYLVTEYAKNGEI--FDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRD 142
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TKSDI 671
LKAEN+LL I KI DFG S + +T G+P Y APE+ EGQ Y+ + DI
Sbjct: 143 LKAENLLLDNNMNI--KIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDI 200
Query: 672 WALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSILPNK 851
W++G +LY + F+ TL L + + G + D + LI ML + P+K
Sbjct: 201 WSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSED--CEHLIRRMLVLDPSK 258
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 118 bits (284), Expect = 3e-26
Identities = 80/240 (33%), Positives = 116/240 (48%), Gaps = 1/240 (0%)
Frame = +3
Query: 135 TIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQ 314
T+GKG + V L + +K I + + + I EV+I+ + HP+II YQ
Sbjct: 25 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQ 84
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
+ + + EYA G + F YL + + E F QIL V Y H I+HRD
Sbjct: 85 VMETKSMLYLVTEYAKNGEI--FDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRD 142
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TKSDI 671
LKAEN+LL I KI DFG S + +T G+P Y APE+ EGQ Y+ + DI
Sbjct: 143 LKAENLLLDNNMNI--KIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDI 200
Query: 672 WALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSILPNK 851
W++G +LY + F+ TL L + + G + D + LI ML + P+K
Sbjct: 201 WSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSED--CEHLIRRMLVLDPSK 258
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 118 bits (284), Expect = 3e-26
Identities = 68/194 (35%), Positives = 105/194 (54%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG++G V L + + VK +Q + + EQ +A +L +KHP ++
Sbjct: 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLV 224
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F + + +++ G L F +L+ + + FY +I + Y+H++ I
Sbjct: 225 GLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEHRARFYAAEIASALGYLHSIKI 282
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL G +V + DFG+ K +A + T+T GTP YLAPE+ QPYD
Sbjct: 283 VYRDLKPENILLDS-VGHVV-LTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 341 TVDWWCLGAVLYEM 354
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 118 bits (284), Expect = 3e-26
Identities = 68/194 (35%), Positives = 105/194 (54%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG++G V L + + VK +Q + + EQ +A +L +KHP ++
Sbjct: 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLV 224
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F + + +++ G L F +L+ + + FY +I + Y+H++ I
Sbjct: 225 GLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEHRARFYAAEIASALGYLHSIKI 282
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL G +V + DFG+ K +A + T+T GTP YLAPE+ QPYD
Sbjct: 283 VYRDLKPENILLDS-VGHVV-LTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 341 TVDWWCLGAVLYEM 354
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 118 bits (284), Expect = 3e-26
Identities = 68/194 (35%), Positives = 105/194 (54%), Gaps = 3/194 (1%)
Frame = +3
Query: 129 LKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD--IANEVRILSTMKHPNII 302
LK IGKG++G V L + + VK +Q + + EQ +A +L +KHP ++
Sbjct: 98 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLV 157
Query: 303 SFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDI 482
+ F + + +++ G L F +L+ + + FY +I + Y+H++ I
Sbjct: 158 GLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEHRARFYAAEIASALGYLHSIKI 215
Query: 483 IHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLAPELCEGQPYDT 659
++RDLK ENILL G +V + DFG+ K +A + T+T GTP YLAPE+ QPYD
Sbjct: 216 VYRDLKPENILLDS-VGHVV-LTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 660 KSDIWALGCLLYEM 701
D W LG +LYEM
Sbjct: 274 TVDWWCLGAVLYEM 287
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 118 bits (284), Expect = 3e-26
Identities = 80/240 (33%), Positives = 116/240 (48%), Gaps = 1/240 (0%)
Frame = +3
Query: 135 TIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQ 314
T+GKG + V L + +K I + + + I EV+I+ + HP+II YQ
Sbjct: 23 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQ 82
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
+ + + EYA G + F YL + + E F QIL V Y H I+HRD
Sbjct: 83 VMETKSMLYLVTEYAKNGEI--FDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRD 140
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TKSDI 671
LKAEN+LL I KI DFG S + +T G+P Y APE+ EGQ Y+ + DI
Sbjct: 141 LKAENLLLDNNMNI--KIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDI 198
Query: 672 WALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSILPNK 851
W++G +LY + F+ TL L + + G + D + LI ML + P+K
Sbjct: 199 WSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSED--CEHLIRRMLVLDPSK 256
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 118 bits (284), Expect = 3e-26
Identities = 80/240 (33%), Positives = 116/240 (48%), Gaps = 1/240 (0%)
Frame = +3
Query: 135 TIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQ 314
T+GKG + V L + +K I + + + I EV+I+ + HP+II YQ
Sbjct: 49 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQ 108
Query: 315 CFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRD 494
+ + + EYA G + F YL + + E F QIL V Y H I+HRD
Sbjct: 109 VMETKSMLYLVTEYAKNGEI--FDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRD 166
Query: 495 LKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYD-TKSDI 671
LKAEN+LL I KI DFG S + +T G+P Y APE+ EGQ Y+ + DI
Sbjct: 167 LKAENLLLDNNMNI--KIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDI 224
Query: 672 WALGCLLYEMCTHKRAFESETLVGLVKAITSGSVHPIDLVLYDRXMQDLIDSMLSILPNK 851
W++G +LY + F+ TL L + + G + D + LI ML + P+K
Sbjct: 225 WSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSED--CEHLIRRMLVLDPSK 282
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 118 bits (284), Expect = 3e-26
Identities = 79/253 (31%), Positives = 126/253 (49%), Gaps = 5/253 (1%)
Frame = +3
Query: 9 SHTXXTPTGIPXXX*MXEXXFASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHEN 188
S + PT P M +SG L FT I + +GKG +GNVYL ++
Sbjct: 43 SRSNVQPTAAPGQKVMEN---SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKS 99
Query: 189 HLLTIVKDIQLNAKIQQH--EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYAT 362
H + +K + ++I++ E + E+ I + + HPNI+ Y FY + + +EYA
Sbjct: 100 HFIVALK-VLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAP 158
Query: 363 CGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIV 542
G L + + C ++ ++ + Y H +IHRD+K EN+LL G G +
Sbjct: 159 RGELYKELQKSC--TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL-GLKGEL- 214
Query: 543 KIGDFGISKMLASAKKTSTVIGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCT---HK 713
KI DFG S + A++ + T+ GT YL PE+ EG+ + K D+W +G L YE+ +
Sbjct: 215 KIADFGWS-VHATSLRRKTMCGTLDYLPPEMIEGRIDNEKVDLWCIGVLCYELLVGNPFE 273
Query: 714 RAFESETLVGLVK 752
A +ET +VK
Sbjct: 274 SASHNETYRRIVK 286
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 205 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 258
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 259 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 318
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 319 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 377
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 378 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 415
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 205 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 258
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 259 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 318
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 319 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 377
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 378 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 415
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 108 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 161
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 162 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 221
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 222 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 280
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 281 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 318
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 118 bits (283), Expect = 4e-26
Identities = 64/212 (30%), Positives = 115/212 (54%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
L+ D + + +L+ +G+G+YG+VY + E + +K + + + +Q+ I
Sbjct: 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE----IIK 72
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFC 440
E+ I+ P+++ +Y ++ + I MEY G++++ + LR + + ++EI
Sbjct: 73 EISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLR-NKTLTEDEIATILQ 131
Query: 441 QILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAK-KTSTVIGTPY 617
L G+ Y+H + IHRD+KA NILL + K+ DFG++ L K +TVIGTP+
Sbjct: 132 STLKGLEYLHFMRKIHRDIKAGNILLNTEGH--AKLADFGVAGQLTDTMAKRNTVIGTPF 189
Query: 618 YLAPELCEGQPYDTKSDIWALGCLLYEMCTHK 713
+APE+ + Y+ +DIW+LG EM K
Sbjct: 190 LMAPEVIQEIGYNCVADIWSLGITAIEMAEGK 221
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 118 bits (283), Expect = 4e-26
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 362 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 415
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 416 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 475
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 476 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 534
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 535 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 572
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 362 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 415
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 416 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 475
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 476 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 534
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 535 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 572
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 639 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 692
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 693 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 752
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 753 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 811
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 812 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 849
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 118 bits (283), Expect = 4e-26
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 33 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 92
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 93 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 149
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 150 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 205
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG
Sbjct: 206 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 260
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 118 bits (283), Expect = 4e-26
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 15 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 74
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 75 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 131
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 132 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 187
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG
Sbjct: 188 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 242
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 118 bits (283), Expect = 4e-26
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 118 bits (283), Expect = 4e-26
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 69 FASGLEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENH--ENHLLTIVKDIQLNAKIQQH 242
F E QN + KT+G G++G V L ++ E + + D Q K++Q
Sbjct: 27 FLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQI 86
Query: 243 EQDIANEVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEE 422
E + NE RIL + P ++ F + + MEY G + F +LR +
Sbjct: 87 EHTL-NEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEM--FSHLRRIGRFSEPH 143
Query: 423 ILFYFCQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKKTSTV 602
FY QI+L Y+H+LD+I+RDLK EN+L+ + G I ++ DFG +K + +T T+
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQ-GYI-QVTDFGFAKRVKG--RTWTL 199
Query: 603 IGTPYYLAPELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESETLVGLVKAITSG 767
GTP YLAPE+ + Y+ D WALG L+YEM F ++ + + + I SG
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 362 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 415
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 416 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 475
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 476 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 534
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 535 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 572
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 543 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 596
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 597 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 656
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 657 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 715
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 716 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 753
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regulating
kinase 2 protein.
Length = 1288
Score = 118 bits (283), Expect = 4e-26
Identities = 73/218 (33%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Frame = +3
Query: 81 LEMDLQNRFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIAN 260
LE D + T ++L +GKGTYG VY + + +K+I + + Q +
Sbjct: 639 LEFDYEYTETGERL----VLGKGTYGVVYAGRDRHTRVRIAIKEIP--ERDSRFSQPLHE 692
Query: 261 EVRILSTMKHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMY-LRCPQVIKQEEILFYF 437
E+ + ++H NI+ + Y+ I ME G+L+ + + P + I FY
Sbjct: 693 EIALHRRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYT 752
Query: 438 CQILLGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKMLASAKK-TSTVIGTP 614
QIL G+ Y+H+ I+HRD+K +N+L+ G++ KI DFG SK LA T T GT
Sbjct: 753 RQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLL-KISDFGTSKRLAGITPCTETFTGTL 811
Query: 615 YYLAPELCEGQP--YDTKSDIWALGCLLYEMCTHKRAF 722
Y+APE+ + P Y +DIW+LGC + EM T + F
Sbjct: 812 QYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPF 849
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 117 bits (282), Expect = 5e-26
Identities = 69/215 (32%), Positives = 112/215 (52%), Gaps = 5/215 (2%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILS 278
+F Q +G+G +G V L E + + +K ++ + + E D + E RI
Sbjct: 651 QFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE 710
Query: 279 TM---KHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
T+ +HP +++ + CF +++V MEYA G+L M++ V + +FY ++
Sbjct: 711 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHT-DVFSEPRAVFYAACVV 767
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLA 626
LG+ Y+H I++RDLK +N+LL + VKI DFG+ K + +TST GTP +LA
Sbjct: 768 LGLQYLHEHKIVYRDLKLDNLLLDTEG--FVKIADFGLCKEGMGYGDRTSTFCGTPEFLA 825
Query: 627 PELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESE 731
PE+ Y D W LG L+YEM + F +
Sbjct: 826 PEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGD 860
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 117 bits (282), Expect = 5e-26
Identities = 69/215 (32%), Positives = 112/215 (52%), Gaps = 5/215 (2%)
Frame = +3
Query: 102 RFTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQD-IANEVRILS 278
+F Q +G+G +G V L E + + +K ++ + + E D + E RI
Sbjct: 651 QFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE 710
Query: 279 TM---KHPNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQIL 449
T+ +HP +++ + CF +++V MEYA G+L M++ V + +FY ++
Sbjct: 711 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHT-DVFSEPRAVFYAACVV 767
Query: 450 LGVSYIHNLDIIHRDLKAENILLTGKYGIIVKIGDFGISKM-LASAKKTSTVIGTPYYLA 626
LG+ Y+H I++RDLK +N+LL + VKI DFG+ K + +TST GTP +LA
Sbjct: 768 LGLQYLHEHKIVYRDLKLDNLLLDTEG--FVKIADFGLCKEGMGYGDRTSTFCGTPEFLA 825
Query: 627 PELCEGQPYDTKSDIWALGCLLYEMCTHKRAFESE 731
PE+ Y D W LG L+YEM + F +
Sbjct: 826 PEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGD 860
>D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein.
Length = 1626
Score = 117 bits (282), Expect = 5e-26
Identities = 73/224 (32%), Positives = 121/224 (54%), Gaps = 9/224 (4%)
Frame = +3
Query: 138 IGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTMKHPNIISFYQC 317
IG+G YG VY C + + L +K+I+ + ++ A+E++I +KHPN++ ++
Sbjct: 1367 IGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLVRYFGV 1426
Query: 318 FYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVSYIHNLDIIHRDL 497
+ + I MEY G L E L +++ I Y QI + ++ +H I+HRD+
Sbjct: 1427 ELHREEMYIFMEYCDEGTLEEVSRLG----LQEHVIRLYSKQITIAINVLHEHGIVHRDI 1482
Query: 498 KAENILLTGKYGIIVKIGDFGISKMLASAKKT-----STVIGTPYYLAPEL---CEGQPY 653
K NI LT G+I K+GDFG S L + +T ++ +GT Y+APE+ +G+ +
Sbjct: 1483 KGANIFLTSS-GLI-KLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGH 1540
Query: 654 DTKSDIWALGCLLYEMCTHKRAF-ESETLVGLVKAITSGSVHPI 782
+DIW+LGC++ EM T KR + E E ++ + G PI
Sbjct: 1541 GRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPI 1584
>CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein.
Length = 372
Score = 117 bits (282), Expect = 5e-26
Identities = 71/256 (27%), Positives = 124/256 (48%), Gaps = 6/256 (2%)
Frame = +3
Query: 105 FTNQKLSILKTIGKGTYGNVYLCENHENHLLTIVKDIQLNAKIQQHEQDIANEVRILSTM 284
F N + K +G+G + V C + K ++ + Q +I +E+ +L
Sbjct: 28 FNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELA 87
Query: 285 KH-PNIISFYQCFYAEDYVMISMEYATCGNLAEFMYLRCPQVIKQEEILFYFCQILLGVS 461
K P +I+ ++ + +++ +EYA G + +++ + +++ QIL GV
Sbjct: 88 KSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVY 147
Query: 462 YIHNLDIIHRDLKAENILLTGKYGI-IVKIGDFGISKMLASAKKTSTVIGTPYYLAPELC 638
Y+H +I+H DLK +NILL+ Y + +KI DFG+S+ + A + ++GTP YLAPE+
Sbjct: 148 YLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEIL 207
Query: 639 EGQPYDTKSDIWALGCLLYEMCTHKRAF----ESETLVGLVKAITSGSVHPIDLVLYDRX 806
P T +D+W +G + Y + TH F ET + + + S V +
Sbjct: 208 NYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSV--SQL 265
Query: 807 MQDLIDSMLSILPNKG 854
D I S+L P KG
Sbjct: 266 ATDFIQSLLVKNPEKG 281
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,773,487
Number of Sequences: 237096
Number of extensions: 2554342
Number of successful extensions: 12380
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7125
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7685
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11992411152
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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