Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP14_F_D04.2
(1237 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular org... 382 e-104
UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular or... 261 2e-68
UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular or... 252 1e-65
UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular org... 228 2e-58
UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29; Bacteria|... 221 3e-56
UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyosteliu... 218 3e-55
UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14; Ascomycota|... 215 2e-54
UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Re... 212 2e-53
UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular org... 199 1e-49
UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep... 196 1e-48
UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome sh... 195 2e-48
UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep... 188 3e-46
UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1; ... 185 2e-45
UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4; Pseudomonada... 184 3e-45
UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Re... 170 7e-41
UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma g... 169 1e-40
UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep... 164 4e-39
UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4; Bifidobacter... 163 1e-38
UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GT... 160 6e-38
UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Re... 160 8e-38
UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49; Proteobacte... 159 1e-37
UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4; Sphingomonad... 156 1e-36
UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2; Betaproteoba... 154 4e-36
UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Re... 153 9e-36
UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Re... 153 9e-36
UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Re... 152 2e-35
UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6; Proteobacter... 151 3e-35
UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep... 151 4e-35
UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Re... 151 4e-35
UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep... 151 5e-35
UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus ... 149 1e-34
UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei... 147 6e-34
UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6; Helicobacter... 144 4e-33
UniRef50_UPI0000DADB56 Cluster: hypothetical protein RcanM_01000... 144 5e-33
UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1; Pse... 142 1e-32
UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1; ... 142 2e-32
UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole gen... 140 7e-32
UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei... 137 6e-31
UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus... 136 8e-31
UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7; Clostridium|... 130 1e-28
UniRef50_A5Z385 Cluster: Putative uncharacterized protein; n=1; ... 128 4e-28
UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11; Lactobacill... 128 4e-28
UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7; Ac... 127 7e-28
UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core eudicot... 120 6e-26
UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacteriu... 120 6e-26
UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma ph... 120 1e-25
UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4; Sulfolobacea... 119 1e-25
UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2; Ostreococcus... 118 3e-25
UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium y... 117 7e-25
UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp. ... 116 1e-24
UniRef50_Q1Q0A8 Cluster: Strongly similar to GTP cyclohydrolase ... 115 2e-24
UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium k... 115 3e-24
UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|R... 114 4e-24
UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis group|... 114 5e-24
UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1; Pl... 114 5e-24
UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma marg... 113 7e-24
UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitale... 112 2e-23
UniRef50_Q6MK87 Cluster: FolE protein; n=1; Bdellovibrio bacteri... 109 1e-22
UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium ... 108 3e-22
UniRef50_Q23AG3 Cluster: GTP cyclohydrolase I family protein; n=... 107 4e-22
UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2; ... 107 4e-22
UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula m... 107 8e-22
UniRef50_Q8ZG15 Cluster: GTP cyclohydrolase I; n=129; root|Rep: ... 104 5e-21
UniRef50_Q7XM20 Cluster: OSJNBa0084K01.11 protein; n=4; Oryza sa... 101 4e-20
UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoc... 101 5e-20
UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4; Pyrobaculum|... 100 9e-20
UniRef50_Q19Z80 Cluster: Gp6; n=4; root|Rep: Gp6 - Mycobacterium... 100 2e-19
UniRef50_Q6ME26 Cluster: Probable GTP cyclohydrolase I; n=1; Can... 99 3e-19
UniRef50_A3J0S0 Cluster: GTP cyclohydrolase I; n=28; Bacteroidet... 97 6e-19
UniRef50_UPI000038E307 Cluster: hypothetical protein Faci_030017... 95 4e-18
UniRef50_A4SVK2 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Re... 88 5e-16
UniRef50_Q7N3C4 Cluster: Similarities with GTP cyclohydrolase I;... 85 4e-15
UniRef50_Q2GDH9 Cluster: GTP cyclohydrolase I; n=1; Neorickettsi... 84 8e-15
UniRef50_Q8XZK8 Cluster: GTP cyclohydrolase I; n=29; Betaproteob... 83 1e-14
UniRef50_A7JLM6 Cluster: GTP cyclohydrolase I; n=11; Francisella... 82 3e-14
UniRef50_Q08SR8 Cluster: GTP cyclohydrolase I 2; n=2; Cystobacte... 82 3e-14
UniRef50_A5GUC6 Cluster: GTP cyclohydrolase I; n=28; Cyanobacter... 82 3e-14
UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2; Anaeromyxoba... 81 4e-14
UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1; ... 81 8e-14
UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma w... 77 1e-12
UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP cycloh... 66 2e-09
UniRef50_A0YW77 Cluster: GTP cyclohydrolase I; n=1; Lyngbya sp. ... 39 0.23
UniRef50_Q9WZP8 Cluster: NADPH-dependent 7-cyano-7-deazaguanine ... 38 0.40
UniRef50_Q7NR63 Cluster: Acetylglutamate kinase; n=3; Bacteria|R... 38 0.40
UniRef50_A6GIP6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.6
UniRef50_Q4EE10 Cluster: GTP cyclohydrolase I; n=1; Listeria mon... 34 6.6
UniRef50_Q5AW97 Cluster: Putative uncharacterized protein; n=1; ... 34 6.6
UniRef50_UPI00006C1A5A Cluster: PREDICTED: hypothetical protein;... 34 8.7
UniRef50_Q5FLA3 Cluster: Negative regulator genetic competence; ... 34 8.7
UniRef50_A6RXW6 Cluster: Putative uncharacterized protein; n=1; ... 34 8.7
>UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular
organisms|Rep: GTP cyclohydrolase I - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 382 bits (940), Expect = e-104
Identities = 182/220 (82%), Positives = 197/220 (89%)
Frame = +1
Query: 334 PEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTREALLPDMAN 513
P + N + +S+ P TP+TPRTSTTPGHE CTFHHDLELDH+PPTREALLPDMA
Sbjct: 87 PRLILKTNGSSPDSDGTQPKTPLTPRTSTTPGHEKCTFHHDLELDHKPPTREALLPDMAR 146
Query: 514 SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVK 693
SYRLLL GLGE+P+R GL+KTPERAAKAML+FTKGYDQSLE+VLN A+FDED DEMVVVK
Sbjct: 147 SYRLLLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQSLEDVLNGAVFDEDHDEMVVVK 206
Query: 694 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
DIEMFSMCEHHLVPFYGKVSIGYLP KILGLSKLARIVEIFSRRLQVQERLTKQIA+AV
Sbjct: 207 DIEMFSMCEHHLVPFYGKVSIGYLPCNKILGLSKLARIVEIFSRRLQVQERLTKQIAVAV 266
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
TQAV+PAGVAVV+EGVHMCMVMRGV INSKTV STMLGV
Sbjct: 267 TQAVQPAGVAVVVEGVHMCMVMRGVQKINSKTVTSTMLGV 306
>UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular
organisms|Rep: GTP cyclohydrolase I - Homo sapiens
(Human)
Length = 250
Score = 261 bits (640), Expect = 2e-68
Identities = 123/169 (72%), Positives = 146/169 (86%)
Frame = +1
Query: 487 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 666
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 667 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 846
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 847 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGV +NSKTV STMLGV
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGV 233
>UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular
organisms|Rep: GTP cyclohydrolase I - Caenorhabditis
elegans
Length = 223
Score = 252 bits (617), Expect = 1e-65
Identities = 121/170 (71%), Positives = 140/170 (82%)
Frame = +1
Query: 484 REALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFD 663
+E L M N+Y+ ++ +GED R GLLKTPERAAKAM+ FTKGYD L+E+LN A+FD
Sbjct: 36 KEDHLKSMCNAYQSIIQHVGEDINRQGLLKTPERAAKAMMAFTKGYDDQLDELLNEAVFD 95
Query: 664 EDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQE 843
ED DEMV+VKDIEMFS+CEHHLVPF GKV IGY+P K+LGLSKLARIVE+FSRRLQVQE
Sbjct: 96 EDHDEMVIVKDIEMFSLCEHHLVPFMGKVHIGYIPNKKVLGLSKLARIVEMFSRRLQVQE 155
Query: 844 RLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
RLTKQIA A+ QAV+P+GVAVVIE HMCMVMRGV IN+ T S MLGV
Sbjct: 156 RLTKQIATAMVQAVQPSGVAVVIEASHMCMVMRGVQKINASTTTSCMLGV 205
>UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular
organisms|Rep: GTP cyclohydrolase I - Ajellomyces
capsulatus NAm1
Length = 390
Score = 228 bits (558), Expect = 2e-58
Identities = 103/176 (58%), Positives = 138/176 (78%)
Frame = +1
Query: 463 LDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEV 642
L+ P E +AN+ R +L +GEDPER GLL TPER AKA+++FTKGY++++ ++
Sbjct: 196 LEATPEENEKRTQKLANAVRTVLECIGEDPEREGLLGTPERYAKALMYFTKGYEENVRDL 255
Query: 643 LNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFS 822
+N A+F ED DE+V+VKDIE+FS+CEHHLVPF GK+ IGY+P ++LGLSK AR+ E+FS
Sbjct: 256 VNGAVFHEDHDELVIVKDIEIFSLCEHHLVPFTGKMHIGYIPDRRVLGLSKFARLAEMFS 315
Query: 823 RRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
RRLQVQERLTKQ+A+A+++ ++P GVAVVIE H+CMVMRGV +S T S MLG
Sbjct: 316 RRLQVQERLTKQVALAISEVLKPRGVAVVIESSHLCMVMRGVQKTSSTTTTSCMLG 371
>UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29; Bacteria|Rep:
GTP cyclohydrolase I 1 - Anabaena sp. (strain PCC 7120)
Length = 235
Score = 221 bits (540), Expect = 3e-56
Identities = 108/188 (57%), Positives = 137/188 (72%)
Frame = +1
Query: 448 HHDLELDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQ 627
H+ E + P+ E + M + R +L G+GEDPER GLLKTP+R A+AM F T GY+Q
Sbjct: 33 HNGREPELHQPSEEDM-ESMMGAVRSILVGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQ 91
Query: 628 SLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARI 807
SLEE+LN A+FDE +EMV+V+DI FS+CEHH++PF G+ + Y+P K++GLSKLARI
Sbjct: 92 SLEELLNGAVFDEGHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIPNQKVVGLSKLARI 151
Query: 808 VEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTML 987
VE++SRRLQVQERLT+QIA AV + P GVAVV+E HMCMVMRGV S TV S ML
Sbjct: 152 VEMYSRRLQVQERLTRQIAEAVQTILEPQGVAVVMEASHMCMVMRGVQKPGSWTVTSAML 211
Query: 988 GVSXXXRK 1011
GV +K
Sbjct: 212 GVFQEEQK 219
>UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyostelium
discoideum|Rep: GTP cyclohydrolase I - Dictyostelium
discoideum (Slime mold)
Length = 232
Score = 218 bits (532), Expect = 3e-55
Identities = 101/167 (60%), Positives = 133/167 (79%)
Frame = +1
Query: 493 LLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDT 672
+L M +S + LL+ LGEDP+R GLLKTP R +KA+LFFT+GY+QS++EV+ AIF+E+
Sbjct: 47 VLNTMQSSVKTLLSSLGEDPDREGLLKTPLRMSKALLFFTQGYEQSVDEVIGEAIFNENH 106
Query: 673 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLT 852
EMVVV+DI++FS+CEHH+VPF+GK IGY+P K+LGLSKLAR+ EIF+RRLQVQERLT
Sbjct: 107 HEMVVVRDIDIFSLCEHHMVPFHGKCHIGYIPDQKVLGLSKLARVAEIFARRLQVQERLT 166
Query: 853 KQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+QIA A+ + P GVAVVI+ HMCMVMRGV + T S++ G+
Sbjct: 167 RQIAQAIQAHLNPMGVAVVIDASHMCMVMRGVQKPGASTATSSVCGI 213
>UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14;
Ascomycota|Rep: GTP cyclohydrolase I - Neurospora crassa
Length = 313
Score = 215 bits (525), Expect = 2e-54
Identities = 98/176 (55%), Positives = 131/176 (74%)
Frame = +1
Query: 463 LDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEV 642
L+ ++ L M + R LL +GEDP+R GLL TPER AKAMLF TKGY +++ ++
Sbjct: 118 LEETEAQKQERLDKMKGAVRTLLECIGEDPDREGLLATPERYAKAMLFLTKGYQENVRDI 177
Query: 643 LNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFS 822
+N AIF E +EMV+VKDIE+FSMCEHHLVPF GK+ IGY+P ++G+SKL RI E+F+
Sbjct: 178 VNGAIFQEGHNEMVIVKDIEVFSMCEHHLVPFTGKMHIGYIPSNAVIGISKLPRIAELFA 237
Query: 823 RRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
RRLQ+QERLTK++A A+ + ++P GVAVV+E H+CMVMRGV S T+ S +LG
Sbjct: 238 RRLQIQERLTKEVANAIMEILKPQGVAVVMESSHLCMVMRGVQKTTSSTITSCVLG 293
>UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Rep:
GTP cyclohydrolase I - Chlorobium tepidum
Length = 224
Score = 212 bits (517), Expect = 2e-53
Identities = 98/168 (58%), Positives = 125/168 (74%)
Frame = +1
Query: 487 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 666
E +L M ++ LL G+GEDPER GLL TPER AK++ F TKGY Q E++L A+F E
Sbjct: 38 EEVLGSMTDAVYSLLKGVGEDPEREGLLLTPERVAKSLRFLTKGYRQDPEQLLKKAVFTE 97
Query: 667 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 846
DEMV+VKDI+++SMCEHH++PF+GK + Y+P GKI+GLSK+ R+VE+F+RRLQVQER
Sbjct: 98 SYDEMVLVKDIDIYSMCEHHMLPFFGKAHVAYIPDGKIVGLSKIPRVVEVFARRLQVQER 157
Query: 847 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
LT+QI A+ + P GVAVVIE HMCMVMRGV N+ T S M G
Sbjct: 158 LTQQIRDAIQNVLNPRGVAVVIEATHMCMVMRGVEKQNAVTTTSAMSG 205
>UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular
organisms|Rep: GTP cyclohydrolase I - Acinetobacter sp.
(strain ADP1)
Length = 197
Score = 199 bits (485), Expect = 1e-49
Identities = 95/165 (57%), Positives = 119/165 (72%)
Frame = +1
Query: 496 LPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTD 675
L M SY +LT +GED R GL TP RAAKA F T GY +SLEEV NNA+F D
Sbjct: 13 LMSMQQSYANILTAVGEDLNRPGLKDTPIRAAKAFSFLTSGYGKSLEEVTNNAVFPSDNH 72
Query: 676 EMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTK 855
EMV+VK+IE +S+CEHHL+PFYG+V I YLP+G++LGLSK ARI E+F+RRLQ+QE LT+
Sbjct: 73 EMVLVKNIEFYSLCEHHLLPFYGRVHIAYLPEGQVLGLSKFARITEMFARRLQIQENLTQ 132
Query: 856 QIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
QIA AV + + GVAV+I+ HMCM+MRGV S T + +G
Sbjct: 133 QIAQAVEEVTKARGVAVMIDSAHMCMMMRGVGKQESTTRTVSFIG 177
>UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep:
GTP cyclohydrolase I - Deinococcus radiodurans
Length = 216
Score = 196 bits (478), Expect = 1e-48
Identities = 91/177 (51%), Positives = 124/177 (70%), Gaps = 4/177 (2%)
Frame = +1
Query: 475 PPTREALLPDMANSYRLL----LTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEV 642
P + LPD N+ L L +GEDP+R GL +TP+R AKA + T+GY Q+L +V
Sbjct: 18 PSLKGVPLPDNPNNLEPLTREWLAAIGEDPDREGLQRTPQRVAKAWAYMTEGYGQTLAQV 77
Query: 643 LNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFS 822
+ +F + EMV+VKDIE +SMCEHH++PFYG+ + Y+P +ILGLSK ARIV+++S
Sbjct: 78 VGEGVFAAEGSEMVIVKDIEFYSMCEHHMLPFYGRAHVAYIPGTRILGLSKFARIVDLYS 137
Query: 823 RRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
RRLQVQER+T Q+A AV + + P GVAV++EG+H+CM MRGV NS T S M G+
Sbjct: 138 RRLQVQERITTQVADAVEELLAPKGVAVLMEGIHLCMAMRGVQKQNSSTTTSAMRGL 194
>UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF14609, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 263
Score = 195 bits (475), Expect = 2e-48
Identities = 91/134 (67%), Positives = 113/134 (84%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMV 684
M SY+ +LT LGED R GL +TP RAAKAM F TKGY++S++E+LN+AIFDE+ E+V
Sbjct: 39 MEKSYKDILTELGEDATREGLQRTPLRAAKAMQFLTKGYNESVKEILNDAIFDENHQEVV 98
Query: 685 VVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIA 864
+VKDIEMFS+CEHHLVPF+GK I YLP K++GLSKLARIVE++SRR QVQERLTKQIA
Sbjct: 99 IVKDIEMFSLCEHHLVPFFGKAHIAYLPNKKVVGLSKLARIVEVYSRRFQVQERLTKQIA 158
Query: 865 IAVTQAVRPAGVAV 906
A+++A+ PAGVAV
Sbjct: 159 SAISEALEPAGVAV 172
>UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
GTP cyclohydrolase I - Roseiflexus sp. RS-1
Length = 226
Score = 188 bits (457), Expect = 3e-46
Identities = 89/165 (53%), Positives = 117/165 (70%)
Frame = +1
Query: 499 PDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDE 678
P + ++ R++L +GE+PER GLLKTP R AK T GY + ++N+AIF DE
Sbjct: 44 PAIEDAVRVILKQIGENPEREGLLKTPSRVAKMYAELTAGYHIDPDALINDAIFSVSYDE 103
Query: 679 MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQ 858
MV+VK+IE S+CEHH++PF G+V + Y+P GK++GLSK+ RIVE+F+RRLQVQER+T Q
Sbjct: 104 MVLVKNIEFASLCEHHMLPFMGRVHVAYIPNGKVVGLSKIPRIVEMFARRLQVQERMTVQ 163
Query: 859 IAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
IA + Q + P GVAVV EGVHMC VMRGV + V S M GV
Sbjct: 164 IADFINQRLEPLGVAVVAEGVHMCAVMRGVKKAGATMVTSAMRGV 208
>UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 233
Score = 185 bits (451), Expect = 2e-45
Identities = 86/187 (45%), Positives = 126/187 (67%)
Frame = +1
Query: 376 ELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTREALLPDMANSYRLLLTGLGEDPE 555
E+ P + P + PG T ++ P L + ++ R +L +GE+P+
Sbjct: 52 EMSAPIPVIDPNGLSRPGIGTRT-----RIEESPEQSVKRLGKLGDAVRTMLECIGENPD 106
Query: 556 RAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVP 735
R G+L TPER AKAM+F T+GY Q++ E++NNAIF E EMV+VKDI++FS+CEHH++P
Sbjct: 107 RPGVLNTPERYAKAMMFLTQGYGQNIHEIVNNAIFHEGHHEMVIVKDIDIFSICEHHMLP 166
Query: 736 FYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIE 915
F GK+ I Y+P ++G+SKL RI E+FSRRLQ+QERLTK +A + + ++P GVAVV+E
Sbjct: 167 FIGKMHIAYIPYHSVIGISKLPRIAEMFSRRLQIQERLTKDVANTIMEVLQPQGVAVVME 226
Query: 916 GVHMCMV 936
H+CM+
Sbjct: 227 ASHLCMI 233
>UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4;
Pseudomonadales|Rep: GTP cyclohydrolase I -
Psychrobacter sp. PRwf-1
Length = 201
Score = 184 bits (449), Expect = 3e-45
Identities = 85/158 (53%), Positives = 115/158 (72%)
Frame = +1
Query: 517 YRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKD 696
Y L+ GED R GLL TP RAAKA + T+GY QSL EV NNA+F D E+V+V +
Sbjct: 23 YAKLIASTGEDLNRPGLLDTPTRAAKAFGYLTQGYHQSLTEVTNNAVFPTDNSELVLVHN 82
Query: 697 IEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVT 876
IE +S+CEHHL+PF+G +GYLP GK+LGLSK+ARI+++++RRLQ+QE L++Q+A A+
Sbjct: 83 IEFYSLCEHHLLPFHGVAHVGYLPDGKVLGLSKVARIIDMYARRLQIQESLSQQVAEAIM 142
Query: 877 QAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+ + GVAVV++ HMCM+MRGV S T + MLG
Sbjct: 143 EVTQCRGVAVVMDASHMCMMMRGVNKQLSSTRTTAMLG 180
>UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Rep:
GTP cyclohydrolase I - Brucella suis
Length = 213
Score = 170 bits (413), Expect = 7e-41
Identities = 83/159 (52%), Positives = 110/159 (69%), Gaps = 2/159 (1%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDT--DEMVVVK 693
R LL GEDP+R GLL+TP+R AKA GY +S EEVL F+E D+MV+VK
Sbjct: 38 RTLLLWAGEDPDREGLLETPKRVAKAYQELFGGYSESPEEVLGTT-FEEVAGYDDMVLVK 96
Query: 694 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
DI FS CEHH+VP GK + YLP+G+++GLSK+AR+V+IF+RRLQ QE +T QIA ++
Sbjct: 97 DISFFSHCEHHMVPIIGKAHVAYLPEGRVVGLSKIARVVDIFARRLQTQESITAQIADSM 156
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+ ++P GVAV+IE HMCM MR + S T+ +T G
Sbjct: 157 QRILKPRGVAVMIEAEHMCMAMRSIRKQGSSTITTTFTG 195
>UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma
gondii|Rep: GTP cyclohydrolase I - Toxoplasma gondii
Length = 262
Score = 169 bits (412), Expect = 1e-40
Identities = 99/242 (40%), Positives = 138/242 (57%), Gaps = 15/242 (6%)
Frame = +1
Query: 313 VGKYKKAPEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTREA 492
+ Y PEA +S + ++ G + + P + L R T +
Sbjct: 1 MASYGVTPEAFRSTVCQASNAQHNRSGREFSSTLADVPA---AAYVSKLPHIPRQSTDQG 57
Query: 493 LLPDMANSY----RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIF 660
L D N+ R++L +GED RAGL +TP+R A AM FF++GY ++V+ NA+F
Sbjct: 58 LGEDKKNAIEEGVRMILRAMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALF 117
Query: 661 D-EDTDE----------MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARI 807
E+ E MV V I++ S+CEHHL+PF+GK IGY+P +LG+SK ARI
Sbjct: 118 SVEEGHEDGQYLAGKQGMVTVGRIDISSLCEHHLLPFFGKCHIGYIPDKHVLGISKFARI 177
Query: 808 VEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTML 987
+EI+SRRLQ+QERLT+QIA+AV + +P GVAV++E HMCM MRGV S T L
Sbjct: 178 MEIYSRRLQIQERLTQQIALAVMKVAKPRGVAVLLECTHMCMAMRGVSSPGSVTTTKAFL 237
Query: 988 GV 993
GV
Sbjct: 238 GV 239
>UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
GTP cyclohydrolase I - Frankia sp. EAN1pec
Length = 257
Score = 164 bits (399), Expect = 4e-39
Identities = 83/164 (50%), Positives = 112/164 (68%), Gaps = 2/164 (1%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMV 684
+A + R LL G+GEDP+R GL KTP+R A+A +G + EVL +FDE DEMV
Sbjct: 76 VARAVRELLIGIGEDPDREGLRKTPDRVARAYQEAVEGLGRDPAEVLTT-VFDEGHDEMV 134
Query: 685 VVKDIEMFSMCEHHLVPFYGKVSIGYLP--QGKILGLSKLARIVEIFSRRLQVQERLTKQ 858
+V+DI+ S+CEHHLV F GK + Y+P +G+I GLSKLAR+V++++RR QVQERLT Q
Sbjct: 135 LVRDIDFSSLCEHHLVVFAGKAHVAYIPNEKGQITGLSKLARLVDLYARRPQVQERLTSQ 194
Query: 859 IAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+A A+ + P GV VV+E H+CM MRGV + TV S + G
Sbjct: 195 VADALVDVLDPRGVMVVVEAEHLCMSMRGVRKPGATTVTSAVRG 238
>UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4;
Bifidobacterium|Rep: GTP cyclohydrolase I -
Bifidobacterium longum
Length = 199
Score = 163 bits (395), Expect = 1e-38
Identities = 80/159 (50%), Positives = 112/159 (70%), Gaps = 1/159 (0%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
RL L +GEDPER GL++TP+R A+A G S + L FD DTDE+V+VKDI
Sbjct: 25 RLFLKSIGEDPEREGLVETPDRIARACRELFTGLQASPADALEKH-FDVDTDELVLVKDI 83
Query: 700 EMFSMCEHHLVPFYGKVSIGYLP-QGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVT 876
E++S+CEHHL+PF+G +GY+P + ++GLSKLAR+VE+++RR QVQERLT+QIA A+
Sbjct: 84 ELYSVCEHHLLPFHGVAHVGYIPAKDGVMGLSKLARLVEVYARRPQVQERLTQQIADALV 143
Query: 877 QAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+ GV VV E H+CM MRG+ +++TV S + G+
Sbjct: 144 EYAGARGVIVVTECEHLCMSMRGIKKSSARTVTSAVRGM 182
>UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GTP
cyclohydrolase I - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 198
Score = 160 bits (389), Expect = 6e-38
Identities = 81/161 (50%), Positives = 109/161 (67%), Gaps = 3/161 (1%)
Frame = +1
Query: 517 YRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFD---EDTDEMVV 687
+R LLT LGE+ +R GL +TP+R KA +T GYDQ E+L +F+ E +E++V
Sbjct: 20 WRRLLTHLGENADRQGLRETPQRVEKAWKHWTSGYDQDPAEILK--VFEDGAEQYNELIV 77
Query: 688 VKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAI 867
V+ I ++S CEHHL PF+G +IGY P GKI+GLSKL R+V+ F++RLQVQERLT QIA
Sbjct: 78 VRGIPVYSHCEHHLAPFFGTATIGYTPNGKIVGLSKLTRLVDCFAKRLQVQERLTIQIAD 137
Query: 868 AVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+ + V+P V VVI HMCM RG+ +TV S +LG
Sbjct: 138 TLMEHVQPLSVGVVIRCRHMCMESRGIRTPGEETVTSALLG 178
>UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Rep:
GTP cyclohydrolase I - Streptococcus pyogenes
Length = 194
Score = 160 bits (388), Expect = 8e-38
Identities = 79/156 (50%), Positives = 104/156 (66%), Gaps = 1/156 (0%)
Frame = +1
Query: 529 LTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMF 708
L +GE+P R GLL TP+R AK G + +E A+F E +++V+VKDI +
Sbjct: 22 LEAIGENPNREGLLDTPKRVAKMYAEMFAGLKKDPKEEFT-AVFTEHHEDVVIVKDISFY 80
Query: 709 SMCEHHLVPFYGKVSIGYLPQ-GKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAV 885
SMCEHH VPFYGK I YLP G++ GLSKLAR VE+ S+R Q+QERLT QIA A+ +A+
Sbjct: 81 SMCEHHQVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTAQIADALVEAL 140
Query: 886 RPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
P GV V++E HMCM MRG+ SKT+ +T G+
Sbjct: 141 HPTGVLVLVEAEHMCMTMRGIKKPGSKTITTTARGL 176
>UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49;
Proteobacteria|Rep: GTP cyclohydrolase I - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 204
Score = 159 bits (386), Expect = 1e-37
Identities = 83/175 (47%), Positives = 111/175 (63%), Gaps = 2/175 (1%)
Frame = +1
Query: 472 RPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNN 651
RP +EA + R+LL GEDP R GL TP R AKA GYD E+VL
Sbjct: 16 RPTQKEA-----EEAVRVLLRWAGEDPAREGLKDTPSRVAKAYREIFGGYDLVAEDVLGR 70
Query: 652 AIFDEDT--DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSR 825
F+E + D++V+ KDI +S CEHH+VP GK I YLP G++LGLSK+AR+V+I++R
Sbjct: 71 T-FEEVSGYDDIVLEKDIPFYSHCEHHMVPIIGKAHIAYLPNGRVLGLSKIARVVDIYAR 129
Query: 826 RLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
RLQ QE +T QIA A+ + + P GVAV+IE H+CM MRG+ + T+ +T G
Sbjct: 130 RLQTQEAMTAQIAKAIDETLMPRGVAVMIEAEHLCMAMRGIKKQGATTLTTTFTG 184
>UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4;
Sphingomonadales|Rep: GTP cyclohydrolase I - Zymomonas
mobilis
Length = 220
Score = 156 bits (379), Expect = 1e-36
Identities = 78/189 (41%), Positives = 116/189 (61%), Gaps = 2/189 (1%)
Frame = +1
Query: 433 ENCTFHHDLELDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFT 612
+N T +L P + + ++ + R L+ G+DP+R GL+ TP+R AKA ++
Sbjct: 16 QNITMEEIQDLAVMRPDQVNVPEEIQEAIRSLIRWAGDDPDREGLIDTPKRVAKAWKYYC 75
Query: 613 KGYDQSLEEVLNNAIFDE--DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILG 786
+GY + E L +F+E D++V++KDI +S CEHH+ P G I YLP K++G
Sbjct: 76 RGYREDPENHLKT-VFEEVGGYDDIVLLKDIPFYSHCEHHMAPIMGHAHIAYLPDKKVVG 134
Query: 787 LSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSK 966
LSKLAR+++ ++ RLQ+QERLT Q+A + +RP GVAVVI VH CM RGV N +
Sbjct: 135 LSKLARVLKGYAHRLQIQERLTAQVADCIWNNLRPRGVAVVISAVHSCMAARGVETPNVQ 194
Query: 967 TVXSTMLGV 993
TV T+ G+
Sbjct: 195 TVTKTLRGI 203
>UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2;
Betaproteobacteria|Rep: GTP cyclohydrolase I -
Herminiimonas arsenicoxydans
Length = 215
Score = 154 bits (374), Expect = 4e-36
Identities = 78/163 (47%), Positives = 107/163 (65%), Gaps = 3/163 (1%)
Frame = +1
Query: 511 NSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTD---EM 681
+ +R LL LGE+P R GL +TP+R KA +T GY Q E+L +F + + E+
Sbjct: 35 HDWRRLLIHLGENPNRQGLQETPKRVQKAWQQWTAGYAQDPAEILK--VFSDGAEQYKEL 92
Query: 682 VVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQI 861
++V+ I ++S CEHHL PF+G +IGY P GKI+GLSKL R+V+ ++RRLQVQERLT QI
Sbjct: 93 IIVRGIPVYSHCEHHLAPFFGTATIGYTPNGKIVGLSKLTRLVDCYARRLQVQERLTIQI 152
Query: 862 AIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
A + + V+P V VVI HMCM RG+ +TV S +LG
Sbjct: 153 AETLMEHVQPLSVGVVIRCRHMCMESRGIQTQGEETVTSALLG 195
>UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Rep:
GTP cyclohydrolase 1 - Rickettsia typhi
Length = 190
Score = 153 bits (371), Expect = 9e-36
Identities = 77/170 (45%), Positives = 111/170 (65%), Gaps = 1/170 (0%)
Frame = +1
Query: 478 PTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAI 657
PTRE + + R LL +GEDP R GLLKTP+R + + GY + ++E+LN
Sbjct: 4 PTRE----EAKEAVRTLLRFIGEDPTREGLLKTPDRVINSYMEIFSGYGKDVQEILNTKF 59
Query: 658 FDE-DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQ 834
+D + +++ ++ I+ S CEHH++PF G V I Y+P I+G+SKLARIV IFSRRLQ
Sbjct: 60 YDTYNFQDLISLEGIKFTSFCEHHILPFNGTVHIAYIPDNCIIGVSKLARIVNIFSRRLQ 119
Query: 835 VQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTM 984
+QE++T QIA ++ ++++P GVA+ I H CM MRGV NS V +TM
Sbjct: 120 IQEKMTVQIAESIQESLKPLGVAIKISAFHSCMSMRGVMHDNS--VMNTM 167
>UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Rep:
GTP cyclohydrolase I - Mycobacterium leprae
Length = 205
Score = 153 bits (371), Expect = 9e-36
Identities = 77/159 (48%), Positives = 105/159 (66%), Gaps = 2/159 (1%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
R LL +GEDP+R GL TP R A+A G + VLN +FDE+ +E+V+VK+I
Sbjct: 29 RELLYAIGEDPDREGLADTPARVARACRELFSGLYTDPQTVLNT-MFDEEHNELVIVKEI 87
Query: 700 EMFSMCEHHLVPFYGKVSIGYLP--QGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
M+S CEHHLV F+G IGYLP G++ GLSK+AR+V+++++R QVQERLT QIA A+
Sbjct: 88 PMYSTCEHHLVSFHGVAHIGYLPGADGRVTGLSKIARLVDLYAKRPQVQERLTSQIADAL 147
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+ P GV +V+E H+CM MRGV + T S + G
Sbjct: 148 VSKLDPRGVIIVVEAEHLCMAMRGVRKPGAITTTSAVRG 186
>UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Rep:
GTP cyclohydrolase I - Xylella fastidiosa
Length = 203
Score = 152 bits (368), Expect = 2e-35
Identities = 78/179 (43%), Positives = 107/179 (59%), Gaps = 3/179 (1%)
Frame = +1
Query: 463 LDHRPPTREALLPDMAN-SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEE 639
+DH ++ A + R LL GEDP R GLL TP R +A + GY + +
Sbjct: 1 MDHSKQQNASITQAQAEEAVRTLLRWAGEDPTREGLLDTPRRVVEAYGDWFSGYREDPHD 60
Query: 640 VLNNAIFDEDT--DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVE 813
L F+E + DE++V+++I S CEHH+ P GKV IGYLP GK++G+SKLAR+VE
Sbjct: 61 YLQRT-FEEISGYDELIVLRNITYESHCEHHMAPIIGKVHIGYLPNGKVVGISKLARVVE 119
Query: 814 IFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
++RR Q+QE++T QIA + + + P GV VVIEG H CM RG+ V S MLG
Sbjct: 120 SYARRFQIQEKMTAQIAACIQETLTPRGVGVVIEGAHACMTTRGIHKRGVSMVTSKMLG 178
>UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6;
Proteobacteria|Rep: GTP cyclohydrolase I -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 206
Score = 151 bits (367), Expect = 3e-35
Identities = 73/165 (44%), Positives = 108/165 (65%), Gaps = 2/165 (1%)
Frame = +1
Query: 502 DMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDT--D 675
D+ ++ R +LT +GEDP R GL +TP R A+A + GYDQ+ EE L F+E D
Sbjct: 21 DVEDAIRTILTWIGEDPSREGLSETPARVARAYKSYFAGYDQNPEEYLRKT-FEETAGYD 79
Query: 676 EMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTK 855
EMV++++I S CEHH+ P G+ +GY+P+ +++G+SKLAR+VE ++ RLQ+QER+T
Sbjct: 80 EMVLLRNIPFQSHCEHHMAPIIGRAWVGYVPRSRVVGISKLARVVEAYASRLQIQERMTA 139
Query: 856 QIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+IA + + ++P GVAVVI+ H C+ RGV S MLG
Sbjct: 140 EIANIIDEVLQPQGVAVVIKAAHHCISSRGVKKHGVDLTTSRMLG 184
>UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep:
GTP cyclohydrolase I - Bacillus coagulans 36D1
Length = 215
Score = 151 bits (366), Expect = 4e-35
Identities = 75/159 (47%), Positives = 101/159 (63%), Gaps = 1/159 (0%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAI-FDEDTDEMVVVKD 696
R L+ G+DP+R GL +TP R KA L +T+GY + + L D D E+V+VKD
Sbjct: 41 RSLIDLCGDDPDRDGLQETPYRVLKAFLEYTEGYREDPKLHLAKTFDVDHDHKELVLVKD 100
Query: 697 IEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVT 876
IE +S+CEHH PF+G + Y P KI GLSK+AR+V+ ++RR QVQERLTKQIA AV
Sbjct: 101 IEFYSICEHHFAPFFGVAHVAYFPNEKITGLSKIARMVDGYARRFQVQERLTKQIADAVE 160
Query: 877 QAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+ + P G VV+E HMCM RGV ++ T + G+
Sbjct: 161 EVLEPQGTMVVLEAKHMCMCGRGVKKSDASTTTMSYRGI 199
>UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Rep:
GTP cyclohydrolase I - Bradyrhizobium japonicum
Length = 229
Score = 151 bits (366), Expect = 4e-35
Identities = 77/160 (48%), Positives = 102/160 (63%), Gaps = 2/160 (1%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDT--DEMVVVK 693
+ LL +GE+ ER GLL TP R +A +GY Q EVL+ F E D+ V+V+
Sbjct: 52 KTLLAYIGENTEREGLLDTPRRVVEAFDELYQGYHQCPAEVLDRT-FGETAGYDDFVLVR 110
Query: 694 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
DIE S CEHH++PFYGK I Y P +++GLSKLAR+ +IF+RRLQ QE LT QIA A+
Sbjct: 111 DIEFTSQCEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQTQEHLTAQIAAAI 170
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+ ++P GVAV+IE H CM +RGV + T S G+
Sbjct: 171 DEVLKPRGVAVLIEAEHTCMSVRGVAKHGASTFTSRFTGM 210
>UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep:
GTP cyclohydrolase I - Corynebacterium diphtheriae
Length = 190
Score = 151 bits (365), Expect = 5e-35
Identities = 78/159 (49%), Positives = 103/159 (64%), Gaps = 2/159 (1%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
R LL +GEDP+R GL +TP R AKA G EVL F ED E+V+V+DI
Sbjct: 15 RELLIAVGEDPDREGLQETPARVAKAYAEMFAGLHTDPTEVLAKT-FSEDHREVVLVRDI 73
Query: 700 EMFSMCEHHLVPFYGKVSIGYLP--QGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
++S CEHHLVPF+GK IGY+P GK+ GLSKLAR+V+++++R QVQERLT Q+A A+
Sbjct: 74 PIYSTCEHHLVPFFGKAHIGYIPGESGKVTGLSKLARLVDLYAKRPQVQERLTTQVADAL 133
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
++ V VVIE H+CM MRG+ + T S + G
Sbjct: 134 VDKLQAQAVIVVIECEHLCMAMRGIRKPGAVTTTSAVRG 172
>UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus
terreus NIH2624|Rep: GTP cyclohydrolase I - Aspergillus
terreus (strain NIH 2624)
Length = 216
Score = 149 bits (361), Expect = 1e-34
Identities = 79/162 (48%), Positives = 105/162 (64%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMV 684
+A + R +L +GEDP R GL TPER AKAML+FTKGY +++ + N AIF ED ++
Sbjct: 56 IAKAVRTILECVGEDPGREGLRATPERYAKAMLYFTKGYSENIFDRANGAIFHEDYKGLI 115
Query: 685 VVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIA 864
V+ IGY+P G+ILGLSK+A + E+FSRRLQVQERLT+Q+A
Sbjct: 116 VMH--------------------IGYIPDGRILGLSKMAHLAEVFSRRLQVQERLTEQVA 155
Query: 865 IAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
IAV ++P GV VV+E H+CM+MRGV + S T S M+G
Sbjct: 156 IAVFNVLKPQGVGVVMESSHLCMIMRGVQKVRSTTTTSYMVG 197
>UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2;
Thermoprotei|Rep: GTP cyclohydrolase I - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 193
Score = 147 bits (356), Expect = 6e-34
Identities = 75/157 (47%), Positives = 102/157 (64%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
R++L +GEDPER GL +TP R A +GYD + E F E TD +VVV I
Sbjct: 13 RMILEAIGEDPEREGLRETPRRVADMFEELLEGYDFTEEYTW----FTEATD-LVVVSGI 67
Query: 700 EMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQ 879
+S+CEHHL+PF+G + YLP+GK++GLSK+ RIV +SRRLQ+QER+TKQIA +++
Sbjct: 68 RFYSLCEHHLLPFFGVAHVAYLPRGKVIGLSKIVRIVNKYSRRLQIQERMTKQIADEISK 127
Query: 880 AVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
A V V+ E VH+CM MRGV + TV + + G
Sbjct: 128 ATGSPDVMVITEAVHLCMAMRGVRN-GAPTVVAAVRG 163
>UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6;
Helicobacter|Rep: GTP cyclohydrolase I - Helicobacter
hepaticus
Length = 206
Score = 144 bits (349), Expect = 4e-33
Identities = 64/142 (45%), Positives = 95/142 (66%)
Frame = +1
Query: 517 YRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKD 696
+ L +GE+P R GLL TP+R A A GY +S ++ L + D DEM+V+K
Sbjct: 32 FESLCQNVGENPTREGLLHTPKRIASAFSDMLNGYAKSPKQALGSVFEDGVCDEMIVLKK 91
Query: 697 IEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVT 876
+ +S+CEHHL+PF+G +SIGY+P K++G+S LAR+ E+F+ RLQ+QERLT QIA A+
Sbjct: 92 LHFYSICEHHLLPFFGHISIGYIPDKKLVGISGLARLTEVFTHRLQIQERLTAQIADALI 151
Query: 877 QAVRPAGVAVVIEGVHMCMVMR 942
++P G +V + H+C+ MR
Sbjct: 152 AELKPKGAMIVCQARHLCLEMR 173
>UniRef50_UPI0000DADB56 Cluster: hypothetical protein
RcanM_01000666; n=1; Rickettsia canadensis str.
McKiel|Rep: hypothetical protein RcanM_01000666 -
Rickettsia canadensis str. McKiel
Length = 222
Score = 144 bits (348), Expect = 5e-33
Identities = 71/163 (43%), Positives = 103/163 (63%), Gaps = 1/163 (0%)
Frame = +1
Query: 478 PTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAI 657
P+RE + + R LL +GEDP R GLLKTP+R + + GY++ + E+L+
Sbjct: 36 PSRE----EAKEAVRTLLKFIGEDPNREGLLKTPDRVINSYMEIFSGYEKDVAEILSTKF 91
Query: 658 FDE-DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQ 834
+D + + + + I S CEHH++PF G V I Y+P I+G+SKLARIV +F+RRLQ
Sbjct: 92 YDTCNFQDFISLDGIRFTSFCEHHMLPFNGTVHISYIPDNCIIGISKLARIVNVFARRLQ 151
Query: 835 VQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINS 963
+QE++T QIA +V ++P GVAV I +H CM +RGV NS
Sbjct: 152 IQEKMTVQIAESVQDNLKPLGVAVRISALHSCMSIRGVIQDNS 194
>UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1;
Pseudomonas entomophila L48|Rep: Putative GTP
cyclohydrolase I - Pseudomonas entomophila (strain L48)
Length = 202
Score = 142 bits (345), Expect = 1e-32
Identities = 69/158 (43%), Positives = 100/158 (63%), Gaps = 2/158 (1%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTD--EMVVVKDI 699
+L LGED R GL +TPER K+M+ T GY Q VL F+E ++++++I
Sbjct: 19 ILEYLGEDTNRQGLHETPERFLKSMVAQTVGYSQDPYRVLEK-FFEEVAGYKNLIMLQNI 77
Query: 700 EMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQ 879
SMCEHHL P G ++GY+P G+++GLSKLAR+V+IF++RLQ+QERLT +I +A+ +
Sbjct: 78 HFESMCEHHLAPIVGNATVGYIPNGRVVGLSKLARVVDIFAKRLQIQERLTSEIGLALDE 137
Query: 880 AVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+RP GV V+I H C+ RG N+ + GV
Sbjct: 138 VLRPKGVGVIIRAKHNCLCTRGAYKPNANMTTTYFSGV 175
>UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 216
Score = 142 bits (343), Expect = 2e-32
Identities = 73/163 (44%), Positives = 106/163 (65%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMV 684
+A + R ++ +GEDP R GL +TP R A+A+ FFT+GY +++ EV N+AIF D+ E+V
Sbjct: 53 IAAAAREIICAVGEDPAREGLAETPNRYAEALQFFTQGYSKNIHEVSNDAIFSIDSRELV 112
Query: 685 VVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIA 864
++ IGY+P G++LGLSKL RI E+++RRLQ+QERLTKQ+
Sbjct: 113 IMH--------------------IGYVPNGRVLGLSKLPRIAEVYARRLQIQERLTKQVG 152
Query: 865 IAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
A+ + + P GVAVV+E HMCMVMRGV + T+ +M G+
Sbjct: 153 EAINEVLSPLGVAVVLECTHMCMVMRGVQKTGTVTLTQSMTGL 195
>UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr3 scaffold_158, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 214
Score = 140 bits (339), Expect = 7e-32
Identities = 74/186 (39%), Positives = 114/186 (61%), Gaps = 5/186 (2%)
Frame = +1
Query: 448 HHDLELDHRPPTREALLPD---MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKG 618
H +EL+ P+ + + ++LL GLGED R G+ KTP R AKA+ T+G
Sbjct: 8 HFSVELEDGVNVEVGFEPETLPIEEAVKVLLQGLGEDINREGIRKTPARVAKALCEGTRG 67
Query: 619 YDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQG-KILGLSK 795
Y Q ++++ A+F E +V+V+D+++FS CE L+PF K +GY+P G +++GLSK
Sbjct: 68 YRQKAKDIVQGALFPEAVGGLVIVRDLDLFSYCESCLLPFQVKCHVGYVPSGQQVVGLSK 127
Query: 796 LAR-IVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTV 972
L+R IV + +LQVQERLT+Q++ V+ ++ V VV+E H CMV RG+ + S T
Sbjct: 128 LSRSIVHFYGFKLQVQERLTRQVSETVS-SLLGGDVIVVVEASHSCMVSRGIEKLGSNTA 186
Query: 973 XSTMLG 990
+LG
Sbjct: 187 TMALLG 192
>UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2;
Thermoprotei|Rep: GTP cyclohydrolase I - Cenarchaeum
symbiosum
Length = 189
Score = 137 bits (331), Expect = 6e-31
Identities = 73/144 (50%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
R L+ LGEDP R GL +TP R A+ GY+ E + F ED+D VV +DI
Sbjct: 11 RELIIELGEDPTREGLRETPARMARMYGEIFGGYESDAELSVQ---FSEDSDA-VVARDI 66
Query: 700 EMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV-T 876
+S+CEHH++PF+G + I YLP GK+ G+SKL R+VE +SRRLQ+QERLT+ IA + +
Sbjct: 67 GFYSVCEHHMLPFFGSIHIAYLPDGKVFGVSKLVRLVEKYSRRLQIQERLTRNIADELSS 126
Query: 877 QAVRPAGVAVVIEGVHMCMVMRGV 948
Q V+ GVAVV E H+CM MRGV
Sbjct: 127 QGVK--GVAVVAEAEHLCMKMRGV 148
>UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus
faecalis|Rep: GTP cyclohydrolase I - Enterococcus
faecalis (Streptococcus faecalis)
Length = 186
Score = 136 bits (330), Expect = 8e-31
Identities = 74/150 (49%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE-DTDEMVVVKDIE 702
+L +GED +RAGL+ TP+R AK G + E + +FD + EMV+VKDI
Sbjct: 16 ILEAVGEDTQRAGLIDTPKRVAKMYAEVFSGLTEP--EFDDYKLFDSLNEGEMVLVKDIA 73
Query: 703 MFSMCEHHLVPFYGKVSIGYLPQG-KILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQ 879
+SMCEHHL+PFYGKV + YLP+G K+LGLSKL R+VE ++R VQE LT IA + +
Sbjct: 74 FYSMCEHHLLPFYGKVHVAYLPEGGKVLGLSKLPRLVEHCAKRPTVQEDLTVTIARKLQE 133
Query: 880 AVRPAGVAVVIEGVHMCMVMRGVXXINSKT 969
+ G+AV IE HMCM MRGV S T
Sbjct: 134 NIPVKGIAVAIEAEHMCMTMRGVKTPQSST 163
>UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7;
Clostridium|Rep: GTP cyclohydrolase I - Clostridium
acetobutylicum
Length = 195
Score = 130 bits (313), Expect = 1e-28
Identities = 69/165 (41%), Positives = 101/165 (61%), Gaps = 8/165 (4%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLN--NAIFDEDT-----DE 678
R +L LG+DP+R GL +TP+R AK KG + S +++ N F+ED D
Sbjct: 13 RGILIALGDDPDREGLKETPKRVAKMYEEVFKGMEYSNDDIAEMFNKTFEEDLKESEEDN 72
Query: 679 MVVVKDIEMFSMCEHHLVPFYGK-VSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTK 855
+V+VKDIE+FS CEHHL Y V++ Y+P +++GLSK+ARI ++ SRRLQ+QER+ K
Sbjct: 73 IVLVKDIEIFSHCEHHLTLMYNMTVAVAYIPNKRLIGLSKIARIADMVSRRLQLQERIGK 132
Query: 856 QIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
IA + + +AV+I+G H CM RG+ + T T+ G
Sbjct: 133 DIAEIMEKVTASKDIAVIIKGEHGCMTSRGIKKPGALTTTMTLKG 177
>UniRef50_A5Z385 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 151
Score = 128 bits (308), Expect = 4e-28
Identities = 61/126 (48%), Positives = 86/126 (68%)
Frame = +1
Query: 616 GYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSK 795
G ++S +E L+ F D + +V+ KDI +S CEHHL+PFYGKV I Y+P GK++G+SK
Sbjct: 8 GMNRSPKEHLSKT-FTCDNENVVIEKDITFYSTCEHHLMPFYGKVHIAYIPNGKVVGISK 66
Query: 796 LARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVX 975
LAR VE+++RRLQ+QE++T QIA A+ + + GV V+ + HMCM RG+ SKTV
Sbjct: 67 LARTVEVYARRLQIQEQMTNQIAKALEKYLGAKGVLVMAQAEHMCMSARGIKKPGSKTVT 126
Query: 976 STMLGV 993
GV
Sbjct: 127 FASTGV 132
>UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11;
Lactobacillales|Rep: GTP cyclohydrolase I -
Lactobacillus plantarum
Length = 189
Score = 128 bits (308), Expect = 4e-28
Identities = 68/150 (45%), Positives = 100/150 (66%), Gaps = 4/150 (2%)
Frame = +1
Query: 511 NSYRLLLTGLGEDPERAGLLKTPERAAK--AMLFFTKGYDQSLEEVLNNAIFD-EDTDEM 681
++ R +L+ +GEDP+R GL++TP R A+ A +F TK + N +F E EM
Sbjct: 12 HAVREILSAVGEDPDRPGLVETPARVARMYAEVFATK----TAAPFDNYKLFKVEHPTEM 67
Query: 682 VVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGK-ILGLSKLARIVEIFSRRLQVQERLTKQ 858
V++KDI +SMCEHHL+PF+G V + Y+PQ + ++GLSK+ R+++ S++ VQERLT
Sbjct: 68 VLLKDIPFYSMCEHHLLPFFGTVQVAYVPQHEQVIGLSKIPRLIDYCSQQPNVQERLTVS 127
Query: 859 IAIAVTQAVRPAGVAVVIEGVHMCMVMRGV 948
IA + + + PAG+AV I HMCM MRGV
Sbjct: 128 IATELQRILDPAGIAVSITARHMCMEMRGV 157
>UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7;
Actinomycetales|Rep: GTP cyclohydrolase I precursor -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 219
Score = 127 bits (306), Expect = 7e-28
Identities = 69/155 (44%), Positives = 93/155 (60%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEM 705
LL LG D E +++TP R A G D L N E DE+V+V +I +
Sbjct: 47 LLRALGLDIETDEMVETPRRLVAAYHELLTGPDVDLTTFPNT----EGYDELVLVANIPV 102
Query: 706 FSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAV 885
S+CEHH++PF G +GYLP +ILGLSK AR+VE+ +RR Q QERLT ++A +T +
Sbjct: 103 RSVCEHHMLPFVGVAHVGYLPDERILGLSKFARLVELVARRPQTQERLTTEVADHLTTHL 162
Query: 886 RPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+P GV VVIE H CM +RGV ++TV S + G
Sbjct: 163 QPRGVGVVIEAEHTCMSLRGVRAQGTRTVTSALRG 197
>UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core
eudicotyledons|Rep: GTP cyclohydrolase I - Arabidopsis
thaliana (Mouse-ear cress)
Length = 466
Score = 120 bits (290), Expect = 6e-26
Identities = 69/170 (40%), Positives = 106/170 (62%), Gaps = 12/170 (7%)
Frame = +1
Query: 454 DLELDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSL 633
+L +H+P T + ++ +LLL GL ED R G+ KTP R AKA+ T+GY Q +
Sbjct: 23 ELAFEHQPETLA-----IQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKV 77
Query: 634 EEVLNNAIFDE-DTDE----------MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQG-K 777
++ + +A+F E DE +VVV+D++ +S CE L+PF+ K IGY+P G +
Sbjct: 78 KDYVQSALFPEAGLDEGVGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQR 137
Query: 778 ILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHM 927
+LGLSK +R+ ++F++RLQ +RL I A+ V+PAGVAVV+E H+
Sbjct: 138 VLGLSKFSRVTDVFAKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHI 187
Score = 101 bits (242), Expect = 4e-20
Identities = 65/170 (38%), Positives = 91/170 (53%), Gaps = 6/170 (3%)
Frame = +1
Query: 499 PDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDE 678
P+M ++ +L LGEDP R L+ TP R K ML F + + N A + + E
Sbjct: 268 PEMVSAVVSILKSLGEDPLRKELIATPTRFLKWMLNFQRTNLEMKLNSFNPAKVNGEVKE 327
Query: 679 MVVVKDIEM--FSMCEHHLVPFYGKVSIGYL-PQG---KILGLSKLARIVEIFSRRLQVQ 840
+ ++ M +SMCEHHL+PFYG V IGY +G +G S + IV + +LQVQ
Sbjct: 328 KRLHCELNMPFWSMCEHHLLPFYGVVHIGYFCAEGSNPNPVGSSLMKAIVHFYGFKLQVQ 387
Query: 841 ERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
ER+T+QIA ++ V V VV E H CM+ RG+ S T +LG
Sbjct: 388 ERMTRQIAETLSPLV-GGDVIVVAEAGHTCMISRGIEKFGSSTATIAVLG 436
>UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacterium
nucleatum|Rep: GTP cyclohydrolase I - Fusobacterium
nucleatum subsp. nucleatum
Length = 187
Score = 120 bits (290), Expect = 6e-26
Identities = 59/161 (36%), Positives = 99/161 (61%)
Frame = +1
Query: 511 NSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVV 690
N++ ++ LG+ + L TP+R A + G D +EVL F+ +++E+++
Sbjct: 12 NAFFEVIEALGDVEYKEELKDTPKRIADSYKEIFYGIDIDPKEVLTKT-FEVNSNELIME 70
Query: 691 KDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIA 870
K+++ +SMCEHH +PF+G V I Y+P KI G + +++EI SRR Q+QERLT++IA
Sbjct: 71 KNMDFYSMCEHHFLPFFGTVCIAYVPNKKIFGFGDILKLIEILSRRPQLQERLTEEIAKY 130
Query: 871 VTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+ + + GV VV+E H+C+ MRG N+K + ++ GV
Sbjct: 131 IYEILNCQGVYVVVEAKHLCVTMRGQKKENTKILTTSAKGV 171
>UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma
phagocytophilum HZ|Rep: GTP cyclohydrolase I - Anaplasma
phagocytophilum (strain HZ)
Length = 202
Score = 120 bits (288), Expect = 1e-25
Identities = 60/146 (41%), Positives = 86/146 (58%)
Frame = +1
Query: 496 LPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTD 675
+ + + R+++ +G+DP R GLLKTP R GY L + +D +
Sbjct: 14 IEEAEEAVRVIIRWMGDDPNREGLLKTPRRVLDYYKKSCSGYAPELLSHYSILPYDGSSS 73
Query: 676 EMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTK 855
EMV+VK+I S CEHHL P G I Y+P+ KILG+ +A IV FS+RLQ+QERLT
Sbjct: 74 EMVLVKNIGFSSNCEHHLSPICGVAHIAYMPKEKILGIGSIAHIVGCFSKRLQLQERLTN 133
Query: 856 QIAIAVTQAVRPAGVAVVIEGVHMCM 933
Q+A + + + P GVAV++E H C+
Sbjct: 134 QVAEYLEKILDPHGVAVLLEAEHWCV 159
>UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4;
Sulfolobaceae|Rep: GTP cyclohydrolase I - Sulfolobus
tokodaii
Length = 215
Score = 119 bits (287), Expect = 1e-25
Identities = 63/162 (38%), Positives = 100/162 (61%), Gaps = 7/162 (4%)
Frame = +1
Query: 484 REALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEV----LNN 651
+E ++ ++A R +L LGE+P+R GL +TP R A+A+L T G ++ L+
Sbjct: 15 QEKMVEEIAKRIREILEILGENPDREGLRETPLRVARALLEMTSGLRTPQPQIKTFNLSE 74
Query: 652 AIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYL--PQGKILGLSKLARIVEIFSR 825
E D++++VK+I S+CEHHL+P GKV + Y+ + K+ G SK+ RIV ++
Sbjct: 75 DGISEVEDQIILVKNIGFSSLCEHHLLPIIGKVHVAYIVGQERKVAGFSKIIRIVNYYAS 134
Query: 826 RLQVQERLTKQIAIAVTQA-VRPAGVAVVIEGVHMCMVMRGV 948
R Q+QERL +QIA A+ + + P GV V+ + +HMC +RGV
Sbjct: 135 RPQIQERLVQQIADAIMNSDIHPKGVMVIGDALHMCAYVRGV 176
>UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2;
Ostreococcus|Rep: GTP cyclohydrolase I - Ostreococcus
tauri
Length = 504
Score = 118 bits (284), Expect = 3e-25
Identities = 63/160 (39%), Positives = 93/160 (58%), Gaps = 18/160 (11%)
Frame = +1
Query: 502 DMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDED---- 669
D++ R +L +GED ER GL+ TP R AKA+ F +GYD L A+F+ED
Sbjct: 56 DVSRCVREMLRAMGEDVEREGLMDTPARVAKALAFAMRGYDACPTAALGTALFNEDGLAR 115
Query: 670 -------------TDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ-GKILGLSKLARI 807
T+++V+V+DI +FS C +PFYG + +GY P+ G I+GLSKLAR+
Sbjct: 116 ASSASTKEDVELGTNDVVLVRDIPVFSTCARTFMPFYGVIHVGYAPRAGVIVGLSKLARV 175
Query: 808 VEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHM 927
E++SRRLQ + L + +A A+ P GV V+ G+ +
Sbjct: 176 AEVYSRRLQTPDGLARAVAQALDDVASPLGVGVMFTGMQL 215
Score = 91.5 bits (217), Expect = 4e-17
Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 2/112 (1%)
Frame = +1
Query: 661 DEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYL--PQGKILGLSKLARIVEIFSRRLQ 834
DE D + V +D+ M ++CEHHL+PF+G VS Y+ P + L L IV SRRLQ
Sbjct: 371 DEIEDGVCVTRDLHMSTVCEHHLLPFHGTVSAAYMTGPGAQPLSRDTLQAIVSRHSRRLQ 430
Query: 835 VQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
VQERLT+ IA ++ GV V H+CMV RGV S T + LG
Sbjct: 431 VQERLTRDIAEEISTLTGGVGVIVAARASHLCMVSRGVEKPGSSTCTAVKLG 482
>UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium
yoelii|Rep: GTP cyclohydrolase I - Plasmodium yoelii
yoelii
Length = 315
Score = 117 bits (281), Expect = 7e-25
Identities = 56/138 (40%), Positives = 89/138 (64%), Gaps = 2/138 (1%)
Frame = +1
Query: 565 LLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDED--TDEMVVVKDIEMFSMCEHHLVPF 738
L +T R AKA L+ T+GY S++ V+ +I+ + ++ +KDI ++S+C+HHL+PF
Sbjct: 142 LKRTNNRFAKAFLYLTEGYKMSVKNVIKKSIYKRKYKNNTLIKIKDIHVYSLCKHHLLPF 201
Query: 739 YGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEG 918
G I Y P I+GLSK +RI +I++RRLQ+QE LT I A+ + ++P + V I+
Sbjct: 202 EGLCDIEYNPDKYIMGLSKFSRITDIYARRLQLQEDLTNDICNALKKYLKPLYIKVTIKA 261
Query: 919 VHMCMVMRGVXXINSKTV 972
H+C+ MRGV ++ TV
Sbjct: 262 KHLCINMRGVKEHDAMTV 279
>UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp.
CcI3|Rep: GTP cyclohydrolase I - Frankia sp. (strain
CcI3)
Length = 192
Score = 116 bits (280), Expect = 1e-24
Identities = 66/143 (46%), Positives = 86/143 (60%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDI 699
R LL +GEDP R GL +TP R A+ F G+D E A + ++V V DI
Sbjct: 28 RQLLVEIGEDPGRDGLRETPARYARWWREFV-GFDPGNTET---AFEQVNHGQLVQVNDI 83
Query: 700 EMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQ 879
++S+CEHHL+PF+ +SI YL + K+LGLSK ARI + RLQVQERLT IA A+
Sbjct: 84 RVWSLCEHHLLPFWCDISIAYLAKDKLLGLSKFARIAHHHAHRLQVQERLTGAIADAIEA 143
Query: 880 AVRPAGVAVVIEGVHMCMVMRGV 948
VAV +G H+CM MRG+
Sbjct: 144 LCGVPDVAVRAKGEHLCMTMRGI 166
>UniRef50_Q1Q0A8 Cluster: Strongly similar to GTP cyclohydrolase I;
n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to GTP cyclohydrolase I - Candidatus Kuenenia
stuttgartiensis
Length = 212
Score = 115 bits (277), Expect = 2e-24
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 4/150 (2%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYD--QSLEEVLNNAIFDEDTDEM--VVVK 693
+ T LG + A +TP R A++ T+GYD L +V + ++
Sbjct: 35 IFTTLGLNLNTAATKETPHRFINALIESTEGYDGDPKLVKVFETECRGGPDCRLSQIIEG 94
Query: 694 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 873
I F++CEHH +PFYG V +GY+ I+GLSKL R+V +FSRR +VQER+ +QIA +
Sbjct: 95 PIRFFALCEHHCLPFYGVVYVGYISHEHIIGLSKLTRLVHLFSRRFEVQERIGQQIADTL 154
Query: 874 TQAVRPAGVAVVIEGVHMCMVMRGVXXINS 963
Q + P GVAV IE H+C+ MRGV I+S
Sbjct: 155 NQLLLPHGVAVYIEAHHLCVEMRGVKEISS 184
>UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium
knowlesi|Rep: GTP cyclohydrolase I - Plasmodium knowlesi
Length = 451
Score = 115 bits (276), Expect = 3e-24
Identities = 59/183 (32%), Positives = 109/183 (59%), Gaps = 3/183 (1%)
Frame = +1
Query: 433 ENCTFHHDLELDHRPPTR-EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFF 609
E C E + + T+ + + D++ S + +L + P + L KT R + L+
Sbjct: 231 EPCGIDTPRESNEKAGTKKDEQIADISRSIKKILRS-SKVPPKDILKKTGRRFSDTFLYL 289
Query: 610 TKGYDQSLEEVLNNAIFDED--TDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKIL 783
TKGY S+E+V+ +++ + + ++ + I ++S+C+HHL+PF G+ +I Y+P I+
Sbjct: 290 TKGYHMSVEKVIKKSLYKRNYKNNSVIKISGIHIYSLCKHHLLPFEGECTIEYIPNKYIM 349
Query: 784 GLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINS 963
GLSK +R+++IF+RRLQ+QE LT I A+ + ++P + V + H+C+ MRGV ++
Sbjct: 350 GLSKFSRVIDIFARRLQLQEDLTNDICNALGKYLKPKYLHVNLVARHLCINMRGVKEHDA 409
Query: 964 KTV 972
T+
Sbjct: 410 TTI 412
>UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|Rep:
GTP cyclohydrolase I - Plasmodium falciparum
Length = 389
Score = 114 bits (275), Expect = 4e-24
Identities = 53/138 (38%), Positives = 88/138 (63%), Gaps = 2/138 (1%)
Frame = +1
Query: 565 LLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE--DTDEMVVVKDIEMFSMCEHHLVPF 738
L +T R A+ L+ T GY+ +E+++ +++ + ++ V I ++S+C+HHL+PF
Sbjct: 225 LKRTNRRYAETFLYLTNGYNLDIEQIIKRSLYKRMYKNNSIIKVTGIHIYSLCKHHLLPF 284
Query: 739 YGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEG 918
G I Y+P I+GLSK +RIV++FSRRLQ+QE LT I A+ + ++P + V I
Sbjct: 285 EGTCDIEYIPNKYIIGLSKFSRIVDVFSRRLQLQEDLTNDICNALKKYLKPLYIKVSIVA 344
Query: 919 VHMCMVMRGVXXINSKTV 972
H+C+ MRGV ++KT+
Sbjct: 345 KHLCINMRGVKEHDAKTI 362
>UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis
group|Rep: GTP cyclohydrolase I - Ehrlichia ruminantium
(strain Welgevonden)
Length = 190
Score = 114 bits (274), Expect = 5e-24
Identities = 58/146 (39%), Positives = 87/146 (59%), Gaps = 1/146 (0%)
Frame = +1
Query: 502 DMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIF-DEDTDE 678
++ ++ LL+ +G+D +R GL+ TP R A F GY Q + V+ ++ +E D
Sbjct: 11 EVEDAISLLIRWIGDDVDRPGLIGTPRRMLNAYKKFFIGY-QDISLVIGGSVLPNEGYDS 69
Query: 679 MVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQ 858
M+ KDI S CEHH++P GKV+IGY+P I + ++ R+V FS+RLQVQERLT
Sbjct: 70 MITFKDIGFVSYCEHHIIPMRGKVNIGYVPDKVIFTIGQVIRLVNYFSKRLQVQERLTVD 129
Query: 859 IAIAVTQAVRPAGVAVVIEGVHMCMV 936
IA ++ + GV VVI H C++
Sbjct: 130 IAESINSYLVSKGVIVVINATHECVL 155
>UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1;
Plasmodium vivax|Rep: GTP cyclohydrolase I, putative -
Plasmodium vivax
Length = 423
Score = 114 bits (274), Expect = 5e-24
Identities = 57/178 (32%), Positives = 102/178 (57%), Gaps = 2/178 (1%)
Frame = +1
Query: 481 TREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIF 660
++E + ++ S +L+ P+ L +T +R L+ TKGY ++ +V+ +++
Sbjct: 218 SKETQMEAISKSINHILSSSNVPPKDI-LKRTSKRFTDTFLYLTKGYHMNVGKVIKKSLY 276
Query: 661 DED--TDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQ 834
D + + I ++S+C+HHL+PF G+ SI Y+P ++GLSK +R++ IF+RRLQ
Sbjct: 277 KRKYKNDSRIKISGIHIYSLCKHHLLPFEGECSIEYVPNRYVMGLSKFSRVINIFARRLQ 336
Query: 835 VQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGVSXXXR 1008
+QE LT I A+ + ++P + V + H+C+ MRGV ++ TV + GV R
Sbjct: 337 LQEDLTNDICNALRKYLKPKYIHVNVVARHLCINMRGVREHDATTVTNAYYGVDEGAR 394
>UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma
marginale str. St. Maries|Rep: GTP cyclohydrolase -
Anaplasma marginale (strain St. Maries)
Length = 198
Score = 113 bits (273), Expect = 7e-24
Identities = 59/176 (33%), Positives = 98/176 (55%), Gaps = 2/176 (1%)
Frame = +1
Query: 469 HRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLN 648
H+ R+ D + +L+ + + P+ GL T R A +GY
Sbjct: 2 HKDLARKPSDKDAEEAIEVLIRWIDDSPDMEGLSLTAGRVLNAYKESFQGYALESSHDFR 61
Query: 649 NAIF-DEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSR 825
N++F +E +M++++ + S CEHH+ P G V+I Y+P+ ++G+ + R+V+IF++
Sbjct: 62 NSVFANEGYSDMILLRGVNFSSTCEHHMSPMAGVVNISYIPKATVIGVGTVVRVVDIFAK 121
Query: 826 RLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINS-KTVXSTMLG 990
RLQVQER+T QIA +++ ++PAGVAV+IE H C G ++ K S MLG
Sbjct: 122 RLQVQERMTVQIAQFLSELLKPAGVAVLIEAKHWCAKYLGGEAVSDLKLQTSCMLG 177
>UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitalea
biformata HTCC2501|Rep: GTP cyclohydrolase I -
Robiginitalea biformata HTCC2501
Length = 176
Score = 112 bits (269), Expect = 2e-23
Identities = 61/157 (38%), Positives = 92/157 (58%), Gaps = 3/157 (1%)
Frame = +1
Query: 529 LTGLGEDPERAGLLKTPERAAKAMLFFT-KGYDQSLEEVLNNAIFDE--DTDEMVVVKDI 699
+ LG D L TP R A+ + T +G S + + F++ T EM+VV DI
Sbjct: 1 MQALGMDLSDTSLADTPMRVARMYVNETFRGL--SAKNFPRISFFEKAPGTPEMIVVNDI 58
Query: 700 EMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQ 879
++S CEHH VPF+GKV + Y+P ++LGLSK+ R+V+ SR+ +QERLT++IA +++
Sbjct: 59 TLYSYCEHHFVPFFGKVHVAYIPGDRLLGLSKVNRVVDYLSRKPHLQERLTREIADTLSE 118
Query: 880 AVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
++ VAV +E H+C+ RGV S T LG
Sbjct: 119 LLQTRHVAVFVEAQHLCVASRGVRDAKSITRTGCYLG 155
>UniRef50_Q6MK87 Cluster: FolE protein; n=1; Bdellovibrio
bacteriovorus|Rep: FolE protein - Bdellovibrio
bacteriovorus
Length = 242
Score = 109 bits (263), Expect = 1e-22
Identities = 63/176 (35%), Positives = 95/176 (53%), Gaps = 2/176 (1%)
Frame = +1
Query: 469 HRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLN 648
H T E + + + ++ LG D + L +TP+R AK + G ++
Sbjct: 48 HNGLTNEEKIERITEKFTDIMNTLGLDLKDDSLRETPKRVAKMYVNEVFG-GLDPKKFPK 106
Query: 649 NAIFDE--DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFS 822
+ D + D+M+VV+ I S CEHH +P G ++ Y+P K++GLSK+ RIV+ FS
Sbjct: 107 MTVIDNKMNYDQMIVVQSIGCLSFCEHHFLPIDGFATVAYIPNKKVIGLSKINRIVQYFS 166
Query: 823 RRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
RR QVQERLTKQIA + + +AV I H C++MRG+ +S T S + G
Sbjct: 167 RRPQVQERLTKQIADCLQYILDTEHIAVHINAKHYCVMMRGIEDTSSTTSTSDLRG 222
>UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium
phytofermentans ISDg|Rep: GTP cyclohydrolase I -
Clostridium phytofermentans ISDg
Length = 194
Score = 108 bits (260), Expect = 3e-22
Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 8/164 (4%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLN--NAIFDEDTDE-----MV 684
+L LGEDP R GL+ TP+R A G + ++++ N F+ED + +V
Sbjct: 15 ILIALGEDPLREGLIDTPKRVANMYEEVFLGIQYTNDDIVTMFNKCFEEDQNTFLANGIV 74
Query: 685 VVKDIEMFSMCEHHLVPFYGK-VSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQI 861
+KDIE FS CEHH+ Y ++IGY P K++G+SK+ARI ++ +RLQ+QER+ I
Sbjct: 75 WIKDIECFSFCEHHMTLIYDMHITIGYKPLHKVIGISKIARIADMVCKRLQIQERIASDI 134
Query: 862 AIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+T+ + + IEG H CM RG+ ++ T G+
Sbjct: 135 LEILTKITGSDDIFIKIEGKHGCMTSRGIQKPHATTCTILTSGI 178
>UniRef50_Q23AG3 Cluster: GTP cyclohydrolase I family protein; n=1;
Tetrahymena thermophila SB210|Rep: GTP cyclohydrolase I
family protein - Tetrahymena thermophila SB210
Length = 223
Score = 107 bits (258), Expect = 4e-22
Identities = 60/164 (36%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = +1
Query: 481 TREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLF-FTKGYDQSLEEVLNNAI 657
+ E + + + +L L D + TP R AK + +G D + +
Sbjct: 34 SNEEKIKKIEECFTEILNMLSLDQTDDSICDTPSRVAKMYINEMFQGLDYANFPDMTTID 93
Query: 658 FDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQV 837
+ +EMV ++DI + + CEHH + F G ++ Y+P+ K+LGLSK+ R+V FS+R QV
Sbjct: 94 NKMEYNEMVQIQDIALTTTCEHHFITFDGFATVAYIPKDKVLGLSKINRLVRFFSKRPQV 153
Query: 838 QERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKT 969
QERLTKQI +A+ V VAV I VH C+ RGV NS T
Sbjct: 154 QERLTKQILVALQTIVETEDVAVHINAVHFCVKARGVMDQNSST 197
>UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1504
Score = 107 bits (258), Expect = 4e-22
Identities = 47/90 (52%), Positives = 67/90 (74%)
Frame = +1
Query: 478 PTREALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAI 657
P +A ++A + R LL +GED R GL KTPER AKA+ FFT+GY + E++N AI
Sbjct: 90 PIPQASPTEIAATIRTLLCQIGEDTNRDGLKKTPERYAKALQFFTQGYKEKSNELINGAI 149
Query: 658 FDEDTDEMVVVKDIEMFSMCEHHLVPFYGK 747
F+EDT++MV+V I++FS+CEHH++PF+GK
Sbjct: 150 FNEDTEDMVIVSGIDVFSLCEHHMLPFFGK 179
>UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula
marismortui|Rep: GTP cyclohydrolase I - Haloarcula
marismortui (Halobacterium marismortui)
Length = 210
Score = 107 bits (256), Expect = 8e-22
Identities = 58/144 (40%), Positives = 79/144 (54%), Gaps = 1/144 (0%)
Frame = +1
Query: 520 RLLLTGLGEDPERAGLLKTPERAAKAML-FFTKGYDQSLEEVLNNAIFDEDTDEMVVVKD 696
RLLL G DP+ AGL T R M T+G + ++ FD +TD ++V
Sbjct: 32 RLLLEAAGRDPDSAGLSDTWSRRVPDMFETLTEGARSESKPIMRT--FDAETDGLIVKTG 89
Query: 697 IEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVT 876
I + SMCEHH++PF G + Y P +++GLSKL R V SR+L QE LT+ IA +
Sbjct: 90 IPLHSMCEHHMLPFRGVAHVAYRPGDQMVGLSKLIRYVRWQSRQLTTQETLTRDIAAGLA 149
Query: 877 QAVRPAGVAVVIEGVHMCMVMRGV 948
+ GV V + HMC VMRG+
Sbjct: 150 DELDAHGVVVELTATHMCEVMRGI 173
>UniRef50_Q8ZG15 Cluster: GTP cyclohydrolase I; n=129; root|Rep: GTP
cyclohydrolase I - Yersinia pestis
Length = 220
Score = 104 bits (249), Expect = 5e-21
Identities = 48/107 (44%), Positives = 71/107 (66%)
Frame = +1
Query: 673 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLT 852
DEMV V+DI + S CEHH V GK ++ Y+P+ ++GLSK+ RIV+ F++R QVQERLT
Sbjct: 95 DEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLT 154
Query: 853 KQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
+QI +A+ + VAV I+ VH C+ RG+ S T +++ G+
Sbjct: 155 QQILLALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGL 201
>UniRef50_Q7XM20 Cluster: OSJNBa0084K01.11 protein; n=4; Oryza
sativa|Rep: OSJNBa0084K01.11 protein - Oryza sativa
subsp. japonica (Rice)
Length = 451
Score = 101 bits (242), Expect = 4e-20
Identities = 63/174 (36%), Positives = 96/174 (55%), Gaps = 11/174 (6%)
Frame = +1
Query: 502 DMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTK-GYDQSLEE-VLNN-AIFD--- 663
+M ++ +L LGEDP R L+ TP+R + ++ F D L LNN +++
Sbjct: 255 NMVSAVSSMLLSLGEDPFRKELVGTPQRYVQWLMKFRACNLDVKLNGFTLNNLSVYQSPA 314
Query: 664 -EDTDEMVVVKDIEM--FSMCEHHLVPFYGKVSIGYLP--QGKILGLSKLARIVEIFSRR 828
+ D + ++ + + CEHHL+PFYG V IGYL G+++ S +V + +
Sbjct: 315 GDAADHRAIHSELHLPFCAQCEHHLLPFYGVVHIGYLDGGDGEVIDRSHFQALVHFYGCK 374
Query: 829 LQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
LQVQER+T+QIA AV +V G VV+E H+CM+ RG+ I S T +LG
Sbjct: 375 LQVQERMTRQIAEAV-YSVSHCGAIVVVEANHICMISRGIEKIRSSTATIAVLG 427
Score = 61.3 bits (142), Expect = 5e-08
Identities = 35/106 (33%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Frame = +1
Query: 613 KGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQG-KILGL 789
KGY Q + +++ A+F E V D S + + F+ +GY+P G +++GL
Sbjct: 67 KGYMQKVRDIVPVALFPE------VGVDQRTGSCWRNWSIQFH----VGYVPSGGRVVGL 116
Query: 790 SKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHM 927
SKL+R+ ++F++RLQ +RL ++ A+ +++PAGVAV ++ H+
Sbjct: 117 SKLSRVADVFAKRLQNPQRLASEVCGALHASIQPAGVAVALQCWHI 162
>UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoccus
hospitalis KIN4/I|Rep: GTP cyclohydrolase - Ignicoccus
hospitalis KIN4/I
Length = 186
Score = 101 bits (241), Expect = 5e-20
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 529 LTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLN-NAIFDEDTDEMVVVKDIEM 705
L +GEDP R GL +TPER +A+ KG + E+ + ++++VVK++
Sbjct: 14 LEEMGEDPSRPGLSETPERYVRALRELFKGLETPKPELKTFKTEYLLGENDLIVVKNVSF 73
Query: 706 FSMCEHHLVPFYGKVSIGYLP-QGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQA 882
S+CEHHL+P G+ SI Y P + +++GLSK+ RIV+ ++R +QER T IA + +A
Sbjct: 74 SSLCEHHLLPILGRASIVYHPKRDEVIGLSKIPRIVKWLAKRPMLQERFTAMIADEIMKA 133
Query: 883 VRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
GV V++ H C+ +RGV + + + + G
Sbjct: 134 -GARGVYVLVRAKHSCVAVRGVEDPDVEMITEAVRG 168
>UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4;
Pyrobaculum|Rep: GTP cyclohydrolase I - Pyrobaculum
aerophilum
Length = 187
Score = 100 bits (239), Expect = 9e-20
Identities = 55/141 (39%), Positives = 85/141 (60%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEM 705
LL LGED + G+L TP+R KAM T+G + EV+ + + VV+++I
Sbjct: 18 LLEYLGEDLTKPGVLNTPKRFVKAMEELTRGLREPPPEVVFFPLEYDVELGPVVIENIGA 77
Query: 706 FSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAV 885
S+CEHHL+P ++S+ Y+P + GLSK+ R+V+ + R +QER T+ +A + + +
Sbjct: 78 VSLCEHHLLPILLRISVAYVPGDGVPGLSKVIRLVKWAAARPIMQERFTEWLADLLMEKL 137
Query: 886 RPAGVAVVIEGVHMCMVMRGV 948
R GV V + GVHMC +RGV
Sbjct: 138 RAKGVQVKVCGVHMCSFIRGV 158
>UniRef50_Q19Z80 Cluster: Gp6; n=4; root|Rep: Gp6 - Mycobacterium
phage Qyrzula
Length = 191
Score = 99.5 bits (237), Expect = 2e-19
Identities = 52/142 (36%), Positives = 78/142 (54%), Gaps = 2/142 (1%)
Frame = +1
Query: 574 TPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVS 753
TP R+AKA GY + + L D V++ +++ SMC HHL+PF G +
Sbjct: 29 TPLRSAKAWSDILSGYREDPADHLEVTFSAPDDPGQVILAGVQLQSMCAHHLLPFTGMAT 88
Query: 754 IGYLPQ--GKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHM 927
+ Y P +++GLSKL+R+V+ ++RRLQVQER+ A+ +RPAG V+I H
Sbjct: 89 VAYRPSPGDRVVGLSKLSRVVQGYARRLQVQERIGADTVDAIMARLRPAGAVVLITASHD 148
Query: 928 CMVMRGVXXINSKTVXSTMLGV 993
CM +RG +S T G+
Sbjct: 149 CMRLRGAQEPHSATTTIASKGL 170
>UniRef50_Q6ME26 Cluster: Probable GTP cyclohydrolase I; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Probable GTP cyclohydrolase I - Protochlamydia
amoebophila (strain UWE25)
Length = 224
Score = 98.7 bits (235), Expect = 3e-19
Identities = 56/166 (33%), Positives = 90/166 (54%), Gaps = 4/166 (2%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAML--FFTKGYDQSLEEV--LNNAIFDEDT 672
+A ++ ++ L D E L +TPER AK + F+ +++ E+ + I E
Sbjct: 38 IAEHFKAIMETLELDVEDESLARTPERVAKMYVNEIFSGLDEENFPEISFFKDEIHHEHK 97
Query: 673 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLT 852
MV VK + S CEHH VP G + Y+P +++GLSK+ R+V F++R Q+QERLT
Sbjct: 98 ANMVFVK-VGFTSFCEHHFVPMSGFAYVAYIPTNQLIGLSKIPRLVRYFAKRPQLQERLT 156
Query: 853 KQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
QIA ++ + VAV + +H C+ RG+ S T+ + + G
Sbjct: 157 AQIADSLALLLNTEHVAVSLTAIHSCVQARGIQDECSHTITNVLRG 202
>UniRef50_A3J0S0 Cluster: GTP cyclohydrolase I; n=28;
Bacteroidetes|Rep: GTP cyclohydrolase I - Flavobacteria
bacterium BAL38
Length = 249
Score = 97.5 bits (232), Expect = 6e-19
Identities = 56/154 (36%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = +1
Query: 517 YRLLLTGLGEDPERAGLLKTPERAAKAMLF-FTKGYDQSLEEVLNNAIFDEDT--DEMVV 687
+ +++ LG D L TP R AK + G + + + ++ +FD D+M+V
Sbjct: 73 FEIIMKELGLDLTDDSLQGTPHRVAKMFVQEIFSGLNPANKPKIS--VFDNSYQYDKMLV 130
Query: 688 VKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAI 867
+I S CEHH +P GK IGY+ GK++GLSKL RIV+ ++RR QVQER+ QI
Sbjct: 131 EANISFNSTCEHHFLPIVGKAHIGYVSSGKVIGLSKLNRIVDYYARRPQVQERMIMQIFN 190
Query: 868 AVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKT 969
+ + V VV+E H+C+ RG+ +S T
Sbjct: 191 ELKTVLETDNVMVVMEATHLCVSSRGIKDESSYT 224
>UniRef50_UPI000038E307 Cluster: hypothetical protein Faci_03001748;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001748 - Ferroplasma acidarmanus fer1
Length = 191
Score = 94.7 bits (225), Expect = 4e-18
Identities = 45/106 (42%), Positives = 68/106 (64%), Gaps = 2/106 (1%)
Frame = +1
Query: 673 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ--GKILGLSKLARIVEIFSRRLQVQER 846
+ MV+VK+I +SMC HHL+PF+G ++I YLP+ G I G+SKL R V + + Q+QE
Sbjct: 63 ESMVIVKNISFYSMCSHHLLPFFGNINIAYLPRPAGYIAGVSKLVRSVNKIASKPQLQEN 122
Query: 847 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTM 984
+T +I + + P V V +G HMCM+MRGV ++ V S++
Sbjct: 123 MTSEIVNLLYDNLNPLFVMVTAKGQHMCMMMRGVKQESATMVTSSV 168
>UniRef50_A4SVK2 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Rep:
GTP cyclohydrolase I - Polynucleobacter sp. QLW-P1DMWA-1
Length = 262
Score = 87.8 bits (208), Expect = 5e-16
Identities = 61/222 (27%), Positives = 103/222 (46%), Gaps = 5/222 (2%)
Frame = +1
Query: 340 ALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDH--RPPTREALLPDMAN 513
++K +S+ + G P++ +N FH + + +P E L+ ++A
Sbjct: 22 SVKKMTPQKIQSKNDDAGLPLSVMIRRRIEAQNARFHANDNISAFIKPGELEGLVDEVAE 81
Query: 514 SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEE-VLNNAIFDEDTDEMVVV 690
+ +L L D K R M + +E+ L +E+++V
Sbjct: 82 KMQAVLESLVIDTNSDHNTKNTSRRVAKMYVQEVFNGRYVEQPTLTKFPNVSRLNELMIV 141
Query: 691 KDIEMFSMCEHHLVPFYGKVSIGYLP--QGKILGLSKLARIVEIFSRRLQVQERLTKQIA 864
I + S C HHL P G++ IG LP + ++GLSK +R+ E R Q+QE ++A
Sbjct: 142 GPITIRSACSHHLCPIMGRIWIGVLPSKESALIGLSKYSRLTEWVMCRPQIQEEAVVELA 201
Query: 865 IAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
+ + ++P GVA+V++ H CM RGV +SK V S M G
Sbjct: 202 DMLEKKIKPIGVAIVMDADHFCMQWRGVKDRDSKMVNSVMRG 243
>UniRef50_Q7N3C4 Cluster: Similarities with GTP cyclohydrolase I;
n=1; Photorhabdus luminescens subsp. laumondii|Rep:
Similarities with GTP cyclohydrolase I - Photorhabdus
luminescens subsp. laumondii
Length = 234
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/164 (39%), Positives = 86/164 (52%), Gaps = 6/164 (3%)
Frame = +1
Query: 493 LLPDMANSYRLLLTGLGEDPERAGLLK-TPERAAKA-MLFFTKGYDQSLEEVLNNAIFDE 666
++ + A S+ LT LG D + K TP R AKA +L KG + + + F
Sbjct: 45 IIDEAAISFGEFLTALGVDWKNDPNSKDTPRRVAKAYVLDLWKGRYKPMGPITT---FPA 101
Query: 667 DTDEMVVVKD-IEMFSMCEHHLVPFYGKVSIGYLPQ--GKILGLSKLARIVEIFSRRLQV 837
D + +V I + SMC HH G V + Y+P G++LGLSKL RIVE F RR +
Sbjct: 102 DNYDGIVFDGWIALDSMCSHHHQAISGYVHVAYMPSQYGRVLGLSKLNRIVEHFGRRGLI 161
Query: 838 QERLTKQIAIAVTQAV-RPAGVAVVIEGVHMCMVMRGVXXINSK 966
QERLT I AV Q R GVAV+++ H C+ RGV S+
Sbjct: 162 QERLTAAIHNAVNQVCERNQGVAVLVDASHNCVRCRGVRHQRSR 205
>UniRef50_Q2GDH9 Cluster: GTP cyclohydrolase I; n=1; Neorickettsia
sennetsu str. Miyayama|Rep: GTP cyclohydrolase I -
Neorickettsia sennetsu (strain Miyayama)
Length = 180
Score = 83.8 bits (198), Expect = 8e-15
Identities = 47/134 (35%), Positives = 70/134 (52%), Gaps = 1/134 (0%)
Frame = +1
Query: 535 GLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDE-MVVVKDIEMFS 711
G+GE +R G K + GY S L + + D E ++V+K S
Sbjct: 16 GVGET-DRLGARGASHSFLKMFANYFSGYACSDFSSLVAKMENPDGGESLLVLKRTPFLS 74
Query: 712 MCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRP 891
CEHH++P G +SIGY+P I L L R+V ++RLQ+QER+ QIA+A+ +++ P
Sbjct: 75 FCEHHVLPISGYISIGYIPDKSITSLGSLGRLVSACTKRLQLQERICAQIALAIEESLSP 134
Query: 892 AGVAVVIEGVHMCM 933
GV V H C+
Sbjct: 135 KGVIVYASAKHACV 148
>UniRef50_Q8XZK8 Cluster: GTP cyclohydrolase I; n=29;
Betaproteobacteria|Rep: GTP cyclohydrolase I - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 209
Score = 83.0 bits (196), Expect = 1e-14
Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKA-MLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIE 702
LL G + + A KT +R + GYD E L + F++ +MV+++ I
Sbjct: 37 LLEASGIEIDTAHTGKTAQRVRELWQRRLLDGYDIDPAEALGHG-FEDPRRDMVIIRSIA 95
Query: 703 MFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQA 882
+ +C HHL+PF G + YLP G++ G ++AR+++ S R QE +T ++A A+
Sbjct: 96 VHGVCPHHLLPFRGVAHVAYLPDGRLHGFGRIARMIDAISHRYTYQEWVTNEVAHALVAH 155
Query: 883 VRPAGVAVVIEGVHMCMVM 939
+ G A +IE +C++M
Sbjct: 156 GQARGAACLIEAEQLCLLM 174
>UniRef50_A7JLM6 Cluster: GTP cyclohydrolase I; n=11; Francisella
tularensis|Rep: GTP cyclohydrolase I - Francisella
tularensis subsp. novicida GA99-3548
Length = 207
Score = 82.2 bits (194), Expect = 3e-14
Identities = 55/168 (32%), Positives = 88/168 (52%), Gaps = 5/168 (2%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLE--EVLNNAIFDEDTDE 678
+ +YR +L LG + KTP R A+ FT+ L+ A+++ + +
Sbjct: 42 ITKAYRQILDALGLYTDE--FEKTPFRVAR---MFTQEIFNGLDYANFPACALYENEFNY 96
Query: 679 MVVV--KDIEMFSMCEHHLVPFYGKVSIGYLPQGK-ILGLSKLARIVEIFSRRLQVQERL 849
V+ K+I + S CEHH VPF G + ++P+ I+GL ++ I + FSRR Q+QER+
Sbjct: 97 TGVLTQKNITIMSFCEHHFVPFEGTAEVSFIPKNNNIIGLCRINSICDFFSRRPQIQERM 156
Query: 850 TKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLGV 993
T QI + + V+V I+ H C+ +RGV NS+T + GV
Sbjct: 157 TAQIFETLKFILSTEDVSVKIKAKHACVSLRGVNNQNSQTYTQMVGGV 204
>UniRef50_Q08SR8 Cluster: GTP cyclohydrolase I 2; n=2;
Cystobacterineae|Rep: GTP cyclohydrolase I 2 -
Stigmatella aurantiaca DW4/3-1
Length = 153
Score = 81.8 bits (193), Expect = 3e-14
Identities = 39/118 (33%), Positives = 64/118 (54%), Gaps = 2/118 (1%)
Frame = +1
Query: 598 MLFFTKGYDQSLEEVLNNAIF--DEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ 771
M F GY + EE + + EMVVV D+ SMC HHL+P+ G+ + Y+P
Sbjct: 1 MTEFLDGYALTPEEAIGTVYPAPPDSAGEMVVVTDLRFHSMCPHHLLPYEGRAHVAYVPG 60
Query: 772 GKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRG 945
++G +L+ +V+ F+ RL +QE L + +A A+ + + A ++E CM +RG
Sbjct: 61 KHVVGFGRLSTLVDCFAHRLILQEDLARHVASALARVLGSPATACILEAKQACMRLRG 118
>UniRef50_A5GUC6 Cluster: GTP cyclohydrolase I; n=28;
Cyanobacteria|Rep: GTP cyclohydrolase I - Synechococcus
sp. (strain RCC307)
Length = 262
Score = 81.8 bits (193), Expect = 3e-14
Identities = 57/179 (31%), Positives = 85/179 (47%), Gaps = 4/179 (2%)
Frame = +1
Query: 466 DH-RPPTREALLPDMANSYRLLLTGLGEDPERA-GLLKTPERAAKAMLFFTKGYDQSLEE 639
DH +P E L ++ + R LL L D ER +T ER AK ++ + + E
Sbjct: 62 DHLKPGELELLQQEVTDKVRDLLRSLVIDIERDHNTEETAERVAK--MYLQEVFKGRYLE 119
Query: 640 VLNNAIFD--EDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVE 813
A F ++ DE+ V I + S C HHLVP G IG P ++GLSK AR+ +
Sbjct: 120 QPKIASFPNVKNLDEIYTVGPITVRSACSHHLVPILGNCWIGIKPGSSVIGLSKFARVAD 179
Query: 814 IFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVXXINSKTVXSTMLG 990
R +QE +A + + P G+A++++ H CM RGV + V S + G
Sbjct: 180 WVFSRPHIQEEAVMILADEIERLCEPKGLAILVKAQHYCMKWRGVKEPQTSMVNSVVRG 238
>UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2;
Anaeromyxobacter|Rep: GTP cyclohydrolase I -
Anaeromyxobacter sp. Fw109-5
Length = 219
Score = 81.4 bits (192), Expect = 4e-14
Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 508 ANSYRLLLTGLGEDPE-RAG--LLKTPERAAKAMLF-FTKGYDQSLEEVLNNAIFDEDTD 675
A + L LG P+ RA L T R A+A L GY + E+L +AI D
Sbjct: 24 AEAVERFLDALGLPPQVRASPDLQGTHRRVAQAWLEDLVDGYRRDPAEILADAIPSPSRD 83
Query: 676 EMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTK 855
+V V I S+C HHL+P G + YLP G+++G +L R+V+ + RL +QE L
Sbjct: 84 -LVAVTGIAFHSVCPHHLLPSRGVAHVAYLPGGRVVGFGQLVRLVDALAHRLVLQEDLAH 142
Query: 856 QIAIAVTQAVRPAGVAVVIEGVHMCMVMRG 945
IA A+ + G A +++ +CM +RG
Sbjct: 143 GIADALVTHLGARGAACLLDAEQLCMTVRG 172
>UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1;
Synechococcus elongatus PCC 7942|Rep: Putative
uncharacterized protein - Synechococcus sp. (strain PCC
7942) (Anacystis nidulans R2)
Length = 227
Score = 80.6 bits (190), Expect = 8e-14
Identities = 42/125 (33%), Positives = 61/125 (48%)
Frame = -2
Query: 930 AHVNSFNDDRHAGRAYGLCHRDGYLLRQTFLYLKTAGEYFHDPGQFAETQNFSLWQVPDG 751
AHV F+DD H R HR L Q L+L+TA + D QFA+ N + V D
Sbjct: 51 AHVGGFHDDGHTLRVEDFLHRLSNLAGQALLHLQTATVHLDDASQFAQADNLLVGDVSDV 110
Query: 750 DLSVKRHQMMFAH*KHLDILNDHHLVRVFIEDGVVQNLFQALVVSFREEEHSFGGTFGRL 571
+ + +R ++F + D+ + HH V F+EDG V + Q L V+ ++ F
Sbjct: 111 NFAHERQHVVFTKAEGGDVTHQHHFVVTFVEDGAVDQVIQGLAVAAGQKAIGLSDPFRGF 170
Query: 570 QEPCP 556
QEP P
Sbjct: 171 QEPFP 175
>UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma
whipplei|Rep: GTP cyclohydrolase I - Tropheryma whipplei
(strain Twist) (Whipple's bacillus)
Length = 181
Score = 76.6 bits (180), Expect = 1e-12
Identities = 46/137 (33%), Positives = 74/137 (54%)
Frame = +1
Query: 526 LLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEM 705
LL+ LG+D R L +TP A+ + G + + + L + I + +V+++DI
Sbjct: 19 LLSALGQDVGR--LKETPSIASSGLESLISGSETNPADCLVDLIPNTQKG-IVILRDIPF 75
Query: 706 FSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAV 885
S+CEHHL+PF G ++ Y P + GL L +V +RRL +QER+T QIA A+ +
Sbjct: 76 RSICEHHLLPFVGTANLLYEPGKFLAGLGNLTSLVRCAARRLSIQERVTDQIADAIYTGL 135
Query: 886 RPAGVAVVIEGVHMCMV 936
V V + H C++
Sbjct: 136 CARRVLVSLAARHTCIL 152
>UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP
cyclohydrolase I (form A; N-terminus), partial; n=1;
Danio rerio|Rep: PREDICTED: similar to GTP
cyclohydrolase I (form A; N-terminus), partial - Danio
rerio
Length = 115
Score = 65.7 bits (153), Expect = 2e-09
Identities = 30/49 (61%), Positives = 36/49 (73%)
Frame = +1
Query: 487 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSL 633
E LP +A +Y +L GLGEDP+R GLLKTP RAA AM FFTKGY + +
Sbjct: 66 EMSLPSIAAAYTTILRGLGEDPQRQGLLKTPWRAATAMQFFTKGYQEKI 114
>UniRef50_A0YW77 Cluster: GTP cyclohydrolase I; n=1; Lyngbya sp. PCC
8106|Rep: GTP cyclohydrolase I - Lyngbya sp. PCC 8106
Length = 62
Score = 39.1 bits (87), Expect = 0.23
Identities = 25/66 (37%), Positives = 34/66 (51%)
Frame = +1
Query: 400 MTPRTSTTPGHENCTFHHDLELDHRPPTREALLPDMANSYRLLLTGLGEDPERAGLLKTP 579
MT S+ G+ N + L+ P E +M + R LL GLGE+P+R GL TP
Sbjct: 1 MTLANSSPKGNPNGNLPN-LKTQSELPVSEE---EMRQAVRTLLLGLGENPDREGLKDTP 56
Query: 580 ERAAKA 597
+R KA
Sbjct: 57 KRVVKA 62
>UniRef50_Q9WZP8 Cluster: NADPH-dependent 7-cyano-7-deazaguanine
reductase (EC 1.7.1.13) (7- cyano-7-carbaguanine
reductase) (PreQ(0) reductase); n=3; Thermotogaceae|Rep:
NADPH-dependent 7-cyano-7-deazaguanine reductase (EC
1.7.1.13) (7- cyano-7-carbaguanine reductase) (PreQ(0)
reductase) - Thermotoga maritima
Length = 137
Score = 38.3 bits (85), Expect = 0.40
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 589 AKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLP 768
A+ +F KG+D + L FD DE + ++ E ++C +P G+V I Y P
Sbjct: 4 AEGRIFDFKGHDAIRTDFLEAIDFD-GKDEYIKIETDEFSAVCPFSGLPDIGRVIIEYYP 62
Query: 769 Q-GKILGLSKLARIVEIFSRRLQVQERLTKQI 861
GKI+ L L F QE TK+I
Sbjct: 63 DGGKIVELKSLKYYFVSFRNVGIYQEEATKRI 94
>UniRef50_Q7NR63 Cluster: Acetylglutamate kinase; n=3; Bacteria|Rep:
Acetylglutamate kinase - Chromobacterium violaceum
Length = 289
Score = 38.3 bits (85), Expect = 0.40
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = -2
Query: 906 DRHAGRAYGLCHRDGYLLRQTFLYLKTAGEYFHDPGQFAETQ 781
++H G+A GL +DG+ +R L+LKT G+ D GQ E +
Sbjct: 114 NKHGGKAVGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIE 155
>UniRef50_A6GIP6 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 207
Score = 36.3 bits (80), Expect = 1.6
Identities = 24/80 (30%), Positives = 37/80 (46%)
Frame = -2
Query: 879 LCHRDGYLLRQTFLYLKTAGEYFHDPGQFAETQNFSLWQVPDGDLSVKRHQMMFAH*KHL 700
L R G ++ L + AGE H+ + E QV G L+ H+++ AH
Sbjct: 13 LHERVGDVVADPLLEGQPAGEAVHELAEPTEADQLVRGQVGHGRLAHPGHEVVRAHPVAR 72
Query: 699 DILNDHHLVRVFIEDGVVQN 640
D+ +DH L EDGV ++
Sbjct: 73 DVPHDHELRVPLAEDGVAED 92
>UniRef50_Q4EE10 Cluster: GTP cyclohydrolase I; n=1; Listeria
monocytogenes str. 4b H7858|Rep: GTP cyclohydrolase I -
Listeria monocytogenes str. 4b H7858
Length = 86
Score = 34.3 bits (75), Expect = 6.6
Identities = 13/30 (43%), Positives = 23/30 (76%)
Frame = +1
Query: 505 MANSYRLLLTGLGEDPERAGLLKTPERAAK 594
+A++ +++L +GE+PER GL+ TP R A+
Sbjct: 30 IADAVKVILEAVGENPEREGLIDTPMRVAR 59
>UniRef50_Q5AW97 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 643
Score = 34.3 bits (75), Expect = 6.6
Identities = 21/60 (35%), Positives = 29/60 (48%)
Frame = +1
Query: 325 KKAPEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTREALLPD 504
++ P+A K AD E ++P P T +ST H +L + PTREAL PD
Sbjct: 407 RRFPKA-KLVTKADVEVAEDMPTRPSTGVSSTLKSFRKSRHGHCQQLKQQEPTREALPPD 465
>UniRef50_UPI00006C1A5A Cluster: PREDICTED: hypothetical protein;
n=2; Homo/Pan/Gorilla group|Rep: PREDICTED: hypothetical
protein - Homo sapiens
Length = 312
Score = 33.9 bits (74), Expect = 8.7
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = -1
Query: 550 GPPPGR*VEACMS*PCPVTTPPWWAVCGPVPGHGGRCSSRDQAWSKSSASLAFRALQVHF 371
GPPP E + P P + CGP GHGG ++ KSS L
Sbjct: 20 GPPPVNKPEMRLLCPSGHNDSPQLSTCGPTKGHGGDVTASLLPVLKSSHQTP--TLSARL 77
Query: 370 P-HRPS*SSSGLLE 332
P +RP SS G L+
Sbjct: 78 PANRPDMSSHGALQ 91
>UniRef50_Q5FLA3 Cluster: Negative regulator genetic competence;
n=1; Lactobacillus acidophilus|Rep: Negative regulator
genetic competence - Lactobacillus acidophilus
Length = 246
Score = 33.9 bits (74), Expect = 8.7
Identities = 23/80 (28%), Positives = 34/80 (42%)
Frame = +1
Query: 499 PDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDE 678
PD AN+ R +++GLG+D + T E FF L+ L+ D+D D
Sbjct: 80 PDEANNLRQMMSGLGDDDNQ-----TQEEPDSRRSFFDLDPKDDLDAQLDQDDEDKDLDA 134
Query: 679 MVVVKDIEMFSMCEHHLVPF 738
DIE + + H F
Sbjct: 135 NEDASDIEYWKFQKRHAYSF 154
>UniRef50_A6RXW6 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 1213
Score = 33.9 bits (74), Expect = 8.7
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +1
Query: 325 KKAPEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDH 471
+KAPEAL N + +P TP +PR+ + HH++E+D+
Sbjct: 127 QKAPEALTVSNYPLSPKNTSIPNTP-SPRSEANDKINSIITHHEIEIDN 174
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 969,383,701
Number of Sequences: 1657284
Number of extensions: 20925981
Number of successful extensions: 58406
Number of sequences better than 10.0: 90
Number of HSP's better than 10.0 without gapping: 54842
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 58198
length of database: 575,637,011
effective HSP length: 103
effective length of database: 404,936,759
effective search space used: 124720521772
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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