Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP12_F_F10
(879 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U43431-2|AAB03695.1| 976|Homo sapiens DNA topoisomerase III pro... 197 5e-50
U43431-1|AAB03694.1| 1001|Homo sapiens DNA topoisomerase III pro... 197 5e-50
BC051748-1|AAH51748.1| 1001|Homo sapiens topoisomerase (DNA) III... 197 5e-50
D87012-1|BAA20009.1| 753|Homo sapiens topoisomerase-III protein. 96 1e-19
CR456596-1|CAG30482.1| 862|Homo sapiens TOP3B protein. 96 1e-19
BC002432-1|AAH02432.1| 862|Homo sapiens topoisomerase (DNA) III... 96 1e-19
AF125216-1|AAD29670.1| 862|Homo sapiens DNA topoisomerase III b... 96 1e-19
AF053082-1|AAD15791.1| 862|Homo sapiens DNA topoisomerase III b... 96 1e-19
AF017146-1|AAD01614.1| 862|Homo sapiens DNA topoisomerase III b... 96 1e-19
U28063-1|AAA92082.1| 232|Homo sapiens aromatic hydrocarbon rece... 31 7.3
L19872-1|AAA16210.1| 848|Homo sapiens AH-receptor protein. 31 7.3
D16354-1|BAA03857.1| 808|Homo sapiens Ah receptor protein. 31 7.3
BC070080-1|AAH70080.1| 848|Homo sapiens AHR protein protein. 31 7.3
BC069390-1|AAH69390.1| 848|Homo sapiens aryl hydrocarbon recept... 31 7.3
AK127075-1|BAC86814.1| 1332|Homo sapiens protein ( Homo sapiens ... 31 7.3
AB028980-1|BAA83009.1| 977|Homo sapiens KIAA1057 protein protein. 31 7.3
>U43431-2|AAB03695.1| 976|Homo sapiens DNA topoisomerase III
protein.
Length = 976
Score = 197 bits (480), Expect = 5e-50
Identities = 95/157 (60%), Positives = 115/157 (73%)
Frame = +3
Query: 408 KYLNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLL 587
K L VAEKNDAAK IA LS G RREGLSK+NKIY+F ++ GQ+ MVMTSVSGHLL
Sbjct: 10 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 69
Query: 588 ALEFSGTYRTWQTCSPLSLFDAPVFKYCPENYQKIKMTLEREVRSCQGLIIWTDCDREGE 767
A +F +R WQ+C+PL LF+A + KYCPEN+ IK TLERE R CQ L+IWTDCDREGE
Sbjct: 70 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 129
Query: 768 NIGFEIIDVCKXCQDKFENI*SKXSEITLVSVNRALQ 878
NIGFEII VCK + + + ++ SEIT +V A +
Sbjct: 130 NIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACE 166
>U43431-1|AAB03694.1| 1001|Homo sapiens DNA topoisomerase III
protein.
Length = 1001
Score = 197 bits (480), Expect = 5e-50
Identities = 95/157 (60%), Positives = 115/157 (73%)
Frame = +3
Query: 408 KYLNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLL 587
K L VAEKNDAAK IA LS G RREGLSK+NKIY+F ++ GQ+ MVMTSVSGHLL
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 588 ALEFSGTYRTWQTCSPLSLFDAPVFKYCPENYQKIKMTLEREVRSCQGLIIWTDCDREGE 767
A +F +R WQ+C+PL LF+A + KYCPEN+ IK TLERE R CQ L+IWTDCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 154
Query: 768 NIGFEIIDVCKXCQDKFENI*SKXSEITLVSVNRALQ 878
NIGFEII VCK + + + ++ SEIT +V A +
Sbjct: 155 NIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACE 191
>BC051748-1|AAH51748.1| 1001|Homo sapiens topoisomerase (DNA) III
alpha protein.
Length = 1001
Score = 197 bits (480), Expect = 5e-50
Identities = 95/157 (60%), Positives = 115/157 (73%)
Frame = +3
Query: 408 KYLNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLL 587
K L VAEKNDAAK IA LS G RREGLSK+NKIY+F ++ GQ+ MVMTSVSGHLL
Sbjct: 35 KVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLL 94
Query: 588 ALEFSGTYRTWQTCSPLSLFDAPVFKYCPENYQKIKMTLEREVRSCQGLIIWTDCDREGE 767
A +F +R WQ+C+PL LF+A + KYCPEN+ IK TLERE R CQ L+IWTDCDREGE
Sbjct: 95 AHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGE 154
Query: 768 NIGFEIIDVCKXCQDKFENI*SKXSEITLVSVNRALQ 878
NIGFEII VCK + + + ++ SEIT +V A +
Sbjct: 155 NIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACE 191
>D87012-1|BAA20009.1| 753|Homo sapiens topoisomerase-III protein.
Length = 753
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>CR456596-1|CAG30482.1| 862|Homo sapiens TOP3B protein.
Length = 862
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>BC002432-1|AAH02432.1| 862|Homo sapiens topoisomerase (DNA) III
beta protein.
Length = 862
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>AF125216-1|AAD29670.1| 862|Homo sapiens DNA topoisomerase III beta
protein.
Length = 862
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>AF053082-1|AAD15791.1| 862|Homo sapiens DNA topoisomerase III beta
protein.
Length = 862
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>AF017146-1|AAD01614.1| 862|Homo sapiens DNA topoisomerase III beta
protein.
Length = 862
Score = 96.3 bits (229), Expect = 1e-19
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Frame = +3
Query: 414 LNVAEKNDAAKNIALHLSKGTSTRREGLSKYNKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
L VAEK A++IA LS+G+ + +GL+ ++++ GQ MTSV GH++ L
Sbjct: 5 LMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTL 64
Query: 594 EFSGTYRTWQTCSPLSLF-DAPVFKYCPENYQKIKMT--LEREVRSCQGLIIWTDCDREG 764
+F G Y W P LF AP K E K+ M L+ E R C +++W DCD+EG
Sbjct: 65 DFLGKYNKWDKVDPAELFSQAPTEK--KEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEG 122
Query: 765 ENIGFEIIDVCKXCQDK 815
ENI FE++D +K
Sbjct: 123 ENICFEVLDAVLPVMNK 139
>U28063-1|AAA92082.1| 232|Homo sapiens aromatic hydrocarbon
receptor protein.
Length = 232
Score = 30.7 bits (66), Expect = 7.3
Identities = 20/89 (22%), Positives = 41/89 (46%)
Frame = +3
Query: 327 EKLNSRLNRTLCFLVNKQIFVNKYSTMKYLNVAEKNDAAKNIALHLSKGTSTRREGLSKY 506
++LN+ L+R L Q +NK + L ++ AK+ K + T R G
Sbjct: 37 DRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDN 96
Query: 507 NKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
+ F+ + Q+ E ++ +++G +L +
Sbjct: 97 CRAANFREGLNLQEGEFLLQALNGFVLVV 125
>L19872-1|AAA16210.1| 848|Homo sapiens AH-receptor protein.
Length = 848
Score = 30.7 bits (66), Expect = 7.3
Identities = 20/89 (22%), Positives = 41/89 (46%)
Frame = +3
Query: 327 EKLNSRLNRTLCFLVNKQIFVNKYSTMKYLNVAEKNDAAKNIALHLSKGTSTRREGLSKY 506
++LN+ L+R L Q +NK + L ++ AK+ K + T R G
Sbjct: 41 DRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDN 100
Query: 507 NKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
+ F+ + Q+ E ++ +++G +L +
Sbjct: 101 CRAANFREGLNLQEGEFLLQALNGFVLVV 129
>D16354-1|BAA03857.1| 808|Homo sapiens Ah receptor protein.
Length = 808
Score = 30.7 bits (66), Expect = 7.3
Identities = 20/89 (22%), Positives = 41/89 (46%)
Frame = +3
Query: 327 EKLNSRLNRTLCFLVNKQIFVNKYSTMKYLNVAEKNDAAKNIALHLSKGTSTRREGLSKY 506
++LN+ L+R L Q +NK + L ++ AK+ K + T R G
Sbjct: 41 DRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDN 100
Query: 507 NKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
+ F+ + Q+ E ++ +++G +L +
Sbjct: 101 CRAANFREGLNLQEGEFLLQALNGFVLVV 129
>BC070080-1|AAH70080.1| 848|Homo sapiens AHR protein protein.
Length = 848
Score = 30.7 bits (66), Expect = 7.3
Identities = 20/89 (22%), Positives = 41/89 (46%)
Frame = +3
Query: 327 EKLNSRLNRTLCFLVNKQIFVNKYSTMKYLNVAEKNDAAKNIALHLSKGTSTRREGLSKY 506
++LN+ L+R L Q +NK + L ++ AK+ K + T R G
Sbjct: 41 DRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDN 100
Query: 507 NKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
+ F+ + Q+ E ++ +++G +L +
Sbjct: 101 CRAANFREGLNLQEGEFLLQALNGFVLVV 129
>BC069390-1|AAH69390.1| 848|Homo sapiens aryl hydrocarbon receptor
protein.
Length = 848
Score = 30.7 bits (66), Expect = 7.3
Identities = 20/89 (22%), Positives = 41/89 (46%)
Frame = +3
Query: 327 EKLNSRLNRTLCFLVNKQIFVNKYSTMKYLNVAEKNDAAKNIALHLSKGTSTRREGLSKY 506
++LN+ L+R L Q +NK + L ++ AK+ K + T R G
Sbjct: 41 DRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDN 100
Query: 507 NKIYQFKANVMGQDCEMVMTSVSGHLLAL 593
+ F+ + Q+ E ++ +++G +L +
Sbjct: 101 CRAANFREGLNLQEGEFLLQALNGFVLVV 129
>AK127075-1|BAC86814.1| 1332|Homo sapiens protein ( Homo sapiens cDNA
FLJ45132 fis, clone BRAWH3037979, highly similar to
Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15).
).
Length = 1332
Score = 30.7 bits (66), Expect = 7.3
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Frame = +3
Query: 648 DAPVFKYCPENYQKIK--MTLEREVRSCQGLIIWTDCDREGENIGFEIIDVCKXCQDK 815
D + K CP Y++ + M L V SCQ L I D GE + C+ C++K
Sbjct: 1058 DQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEK 1115
>AB028980-1|BAA83009.1| 977|Homo sapiens KIAA1057 protein protein.
Length = 977
Score = 30.7 bits (66), Expect = 7.3
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Frame = +3
Query: 648 DAPVFKYCPENYQKIK--MTLEREVRSCQGLIIWTDCDREGENIGFEIIDVCKXCQDK 815
D + K CP Y++ + M L V SCQ L I D GE + C+ C++K
Sbjct: 165 DQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEK 222
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,946,015
Number of Sequences: 237096
Number of extensions: 2129449
Number of successful extensions: 3467
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3461
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11215125244
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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