Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP12_F_A23
(893 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D49387-1|BAA08382.1| 311|Homo sapiens NADP dependent leukotrien... 75 3e-13
BC035228-1|AAH35228.1| 329|Homo sapiens leukotriene B4 12-hydro... 75 3e-13
AL135787-3|CAC22151.1| 329|Homo sapiens leukotriene B4 12-hydro... 75 3e-13
AL135787-2|CAI12401.1| 177|Homo sapiens leukotriene B4 12-hydro... 65 3e-10
BC059364-1|AAH59364.1| 351|Homo sapiens zinc binding alcohol de... 57 8e-08
AY424308-1|AAR82927.1| 351|Homo sapiens zinc binding alcohol de... 57 8e-08
AY346133-1|AAR05101.1| 351|Homo sapiens zinc binding alcohol de... 57 8e-08
AK096410-1|BAC04781.1| 351|Homo sapiens protein ( Homo sapiens ... 57 8e-08
AL135787-4|CAI12402.1| 119|Homo sapiens leukotriene B4 12-hydro... 41 0.005
BC078661-1|AAH78661.1| 377|Homo sapiens zinc binding alcohol de... 40 0.016
BC033780-1|AAH33780.1| 377|Homo sapiens zinc binding alcohol de... 40 0.016
BC018081-1|AAH18081.1| 366|Homo sapiens ZADH2 protein protein. 39 0.028
AL135787-5|CAC22152.1| 70|Homo sapiens leukotriene B4 12-hydro... 38 0.049
>D49387-1|BAA08382.1| 311|Homo sapiens NADP dependent leukotriene
b4 12-hydroxydehydrogenase protein.
Length = 311
Score = 75.4 bits (177), Expect = 3e-13
Identities = 35/68 (51%), Positives = 44/68 (64%)
Frame = +2
Query: 533 SLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGT 712
SL +G VGMPG TAYFG LEIC K S+VGQIAK+KGC+V+G G+
Sbjct: 116 SLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGS 175
Query: 713 DDKVKWLE 736
D+KV +L+
Sbjct: 176 DEKVAYLQ 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 26/47 (55%), Positives = 37/47 (78%), Gaps = 1/47 (2%)
Frame = +3
Query: 738 EELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
++LGFD FNYKTV+ + LK+A+P+G DCYFDNVGGE S+ ++ +
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQ 229
Score = 38.3 bits (85), Expect = 0.037
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +1
Query: 286 KAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVESRDSNYPVGTRVVAHKGWCDHYV 456
+A +++VDPY+R QV VVES++ P GT V+A GW H +
Sbjct: 40 EALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI 96
Score = 37.9 bits (84), Expect = 0.049
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 168 MTSARKYVVKNHFKGVPKREDYELVEFVIPPLIDGEVL 281
M + + +K HF G P D+EL +PPL +GEVL
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38
>BC035228-1|AAH35228.1| 329|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 329
Score = 75.4 bits (177), Expect = 3e-13
Identities = 35/68 (51%), Positives = 44/68 (64%)
Frame = +2
Query: 533 SLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGT 712
SL +G VGMPG TAYFG LEIC K S+VGQIAK+KGC+V+G G+
Sbjct: 116 SLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGS 175
Query: 713 DDKVKWLE 736
D+KV +L+
Sbjct: 176 DEKVAYLQ 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 26/47 (55%), Positives = 37/47 (78%), Gaps = 1/47 (2%)
Frame = +3
Query: 738 EELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
++LGFD FNYKTV+ + LK+A+P+G DCYFDNVGGE S+ ++ +
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQ 229
Score = 38.3 bits (85), Expect = 0.037
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +1
Query: 286 KAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVESRDSNYPVGTRVVAHKGWCDHYV 456
+A +++VDPY+R QV VVES++ P GT V+A GW H +
Sbjct: 40 EALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI 96
Score = 37.9 bits (84), Expect = 0.049
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 168 MTSARKYVVKNHFKGVPKREDYELVEFVIPPLIDGEVL 281
M + + +K HF G P D+EL +PPL +GEVL
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVL 38
>AL135787-3|CAC22151.1| 329|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 329
Score = 75.4 bits (177), Expect = 3e-13
Identities = 35/68 (51%), Positives = 44/68 (64%)
Frame = +2
Query: 533 SLGVGAVGMPGATAYFGFLEICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGT 712
SL +G VGMPG TAYFG LEIC K S+VGQIAK+KGC+V+G G+
Sbjct: 116 SLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGS 175
Query: 713 DDKVKWLE 736
D+KV +L+
Sbjct: 176 DEKVAYLQ 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 26/47 (55%), Positives = 37/47 (78%), Gaps = 1/47 (2%)
Frame = +3
Query: 738 EELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
++LGFD FNYKTV+ + LK+A+P+G DCYFDNVGGE S+ ++ +
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQ 229
Score = 38.3 bits (85), Expect = 0.037
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +1
Query: 286 KAEWISVDPYLRAYNSYQAVPYDQFSYQVGVVVESRDSNYPVGTRVVAHKGWCDHYV 456
+A +++VDPY+R QV VVES++ P GT V+A GW H +
Sbjct: 40 EALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSI 96
Score = 37.9 bits (84), Expect = 0.049
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 168 MTSARKYVVKNHFKGVPKREDYELVEFVIPPLIDGEVL 281
M + + +K HF G P D+EL +PPL +GEVL
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38
>AL135787-2|CAI12401.1| 177|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 177
Score = 65.3 bits (152), Expect = 3e-10
Identities = 30/60 (50%), Positives = 38/60 (63%)
Frame = +2
Query: 557 MPGATAYFGFLEICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGTDDKVKWLE 736
MPG TAYFG LEIC K S+VGQIAK+KGC+V+G G+D+KV +L+
Sbjct: 1 MPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ 60
Score = 62.5 bits (145), Expect = 2e-09
Identities = 26/47 (55%), Positives = 37/47 (78%), Gaps = 1/47 (2%)
Frame = +3
Query: 738 EELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
++LGFD FNYKTV+ + LK+A+P+G DCYFDNVGGE S+ ++ +
Sbjct: 60 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQ 106
>BC059364-1|AAH59364.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 1 protein.
Length = 351
Score = 57.2 bits (132), Expect = 8e-08
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +3
Query: 741 ELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
ELGFD A NYK +V L+E+ P G+D YFDNVGG IS ++++
Sbjct: 199 ELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQ 243
Score = 32.7 bits (71), Expect = 1.8
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Frame = +2
Query: 542 VGAVGMPGATAYFGFLE--ICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGC-RVIGFAGT 712
+GA+GMPG T+ G E S+ GQI GC RV+G GT
Sbjct: 130 LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGT 189
Query: 713 DDK 721
+K
Sbjct: 190 HEK 192
>AY424308-1|AAR82927.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase protein.
Length = 351
Score = 57.2 bits (132), Expect = 8e-08
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +3
Query: 741 ELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
ELGFD A NYK +V L+E+ P G+D YFDNVGG IS ++++
Sbjct: 199 ELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQ 243
Score = 32.7 bits (71), Expect = 1.8
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Frame = +2
Query: 542 VGAVGMPGATAYFGFLE--ICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGC-RVIGFAGT 712
+GA+GMPG T+ G E S+ GQI GC RV+G GT
Sbjct: 130 LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGT 189
Query: 713 DDK 721
+K
Sbjct: 190 HEK 192
>AY346133-1|AAR05101.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase domain containing 1 protein protein.
Length = 351
Score = 57.2 bits (132), Expect = 8e-08
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +3
Query: 741 ELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
ELGFD A NYK +V L+E+ P G+D YFDNVGG IS ++++
Sbjct: 199 ELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQ 243
Score = 32.7 bits (71), Expect = 1.8
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Frame = +2
Query: 542 VGAVGMPGATAYFGFLE--ICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGC-RVIGFAGT 712
+GA+GMPG T+ G E S+ GQI GC RV+G GT
Sbjct: 130 LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGT 189
Query: 713 DDK 721
+K
Sbjct: 190 HEK 192
>AK096410-1|BAC04781.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ39091 fis, clone NT2RP7019543, weakly similar to
NADP-DEPENDENT OXIDOREDUCTASE IN TEHB-RHSE INTERGENIC
REGION ).
Length = 351
Score = 57.2 bits (132), Expect = 8e-08
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +3
Query: 741 ELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGGEISSQILAK 875
ELGFD A NYK +V L+E+ P G+D YFDNVGG IS ++++
Sbjct: 199 ELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQ 243
Score = 32.7 bits (71), Expect = 1.8
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Frame = +2
Query: 542 VGAVGMPGATAYFGFLE--ICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGC-RVIGFAGT 712
+GA+GMPG T+ G E S+ GQI GC RV+G GT
Sbjct: 130 LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGT 189
Query: 713 DDK 721
+K
Sbjct: 190 HEK 192
>AL135787-4|CAI12402.1| 119|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 119
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/22 (77%), Positives = 18/22 (81%)
Frame = +2
Query: 533 SLGVGAVGMPGATAYFGFLEIC 598
SL +G VGMPG TAYFG LEIC
Sbjct: 97 SLALGTVGMPGLTAYFGLLEIC 118
Score = 37.9 bits (84), Expect = 0.049
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 168 MTSARKYVVKNHFKGVPKREDYELVEFVIPPLIDGEVL 281
M + + +K HF G P D+EL +PPL +GEVL
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38
>BC078661-1|AAH78661.1| 377|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 2 protein.
Length = 377
Score = 39.5 bits (88), Expect = 0.016
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +3
Query: 738 EELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGG 848
+ LG D+ NYKT V LK+ P G+D +++VGG
Sbjct: 214 KSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGG 250
>BC033780-1|AAH33780.1| 377|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 2 protein.
Length = 377
Score = 39.5 bits (88), Expect = 0.016
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +3
Query: 738 EELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGG 848
+ LG D+ NYKT V LK+ P G+D +++VGG
Sbjct: 214 KSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGG 250
>BC018081-1|AAH18081.1| 366|Homo sapiens ZADH2 protein protein.
Length = 366
Score = 38.7 bits (86), Expect = 0.028
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +3
Query: 738 EELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNVGG 848
+ LG D NYKT V LK+ P G+D +++VGG
Sbjct: 214 KSLGCDSPINYKTEPVGTVLKQEYPEGVDVVYESVGG 250
>AL135787-5|CAC22152.1| 70|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 70
Score = 37.9 bits (84), Expect = 0.049
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 168 MTSARKYVVKNHFKGVPKREDYELVEFVIPPLIDGEVL 281
M + + +K HF G P D+EL +PPL +GEVL
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVL 38
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,598,573
Number of Sequences: 237096
Number of extensions: 2325741
Number of successful extensions: 5610
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5250
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5606
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11492727354
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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