Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP11_F_F24
(928 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component sub... 243 4e-63
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;... 194 4e-48
UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component sub... 193 5e-48
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub... 188 2e-46
UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, be... 157 4e-37
UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaste... 156 7e-37
UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 143 5e-33
UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, be... 133 7e-30
UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component bet... 131 2e-29
UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1; Opit... 128 2e-28
UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 126 6e-28
UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component sub... 121 2e-26
UniRef50_A6UDY4 Cluster: Transketolase central region; n=1; Sino... 121 3e-26
UniRef50_A5UU14 Cluster: Transketolase, central region; n=3; Chl... 118 2e-25
UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 118 2e-25
UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 117 5e-25
UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component, ... 116 9e-25
UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta ... 116 1e-24
UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate d... 115 2e-24
UniRef50_Q3WCG4 Cluster: Transketolase, central region:Transketo... 115 2e-24
UniRef50_A5V539 Cluster: Transketolase, central region; n=4; Bac... 115 2e-24
UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium ce... 113 5e-24
UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1; Rub... 113 6e-24
UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent dehydr... 112 1e-23
UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, bet... 110 6e-23
UniRef50_A5V352 Cluster: Transketolase, central region; n=1; Sph... 108 2e-22
UniRef50_A1SN85 Cluster: Transketolase, central region; n=4; cel... 108 2e-22
UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=... 108 2e-22
UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, be... 107 4e-22
UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2; Act... 107 4e-22
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 106 9e-22
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 105 1e-21
UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit (L... 105 1e-21
UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component sub... 105 2e-21
UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2; Bac... 104 3e-21
UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma j... 104 3e-21
UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, b... 101 3e-20
UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=... 100 5e-20
UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1; Synt... 100 5e-20
UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 100 5e-20
UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5; Bac... 99 1e-19
UniRef50_A0H598 Cluster: Transketolase, central region; n=2; Chl... 99 1e-19
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 96 1e-18
UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1; ... 96 1e-18
UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 96 1e-18
UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) b... 95 2e-18
UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 94 4e-18
UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 94 5e-18
UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular ... 94 5e-18
UniRef50_A0JY24 Cluster: Transketolase, central region; n=2; cel... 93 1e-17
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_Q479Q1 Cluster: Transketolase, central region:Transketo... 91 3e-17
UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1, tran... 91 4e-17
UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component sub... 91 4e-17
UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component sub... 90 9e-17
UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18; ce... 88 3e-16
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 87 6e-16
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 87 6e-16
UniRef50_A7CXF2 Cluster: Transketolase central region; n=1; Opit... 87 8e-16
UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component sub... 86 1e-15
UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component sub... 86 1e-15
UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2; Bacter... 85 2e-15
UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subun... 82 2e-14
UniRef50_A5V556 Cluster: Transketolase domain protein; n=1; Sphi... 82 2e-14
UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase beta-su... 81 4e-14
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 80 7e-14
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 80 9e-14
UniRef50_A1G854 Cluster: Transketolase, central region; n=3; Act... 80 9e-14
UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16; Bacill... 79 1e-13
UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 78 4e-13
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 78 4e-13
UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 77 5e-13
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 77 6e-13
UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1; Novo... 77 6e-13
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 76 1e-12
UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component bet... 75 3e-12
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 74 5e-12
UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta su... 73 1e-11
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 71 4e-11
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 67 5e-10
UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate... 67 7e-10
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 66 2e-09
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 65 2e-09
UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 64 4e-09
UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1 comp... 62 3e-08
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 61 5e-08
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 58 3e-07
UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2; ... 58 3e-07
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 56 2e-06
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 53 1e-05
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 52 2e-05
UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 52 2e-05
UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit... 52 2e-05
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 52 2e-05
UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 51 4e-05
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 49 2e-04
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 48 3e-04
UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to 2-oxoisova... 45 0.002
UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase ... 41 0.052
UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate... 38 0.28
UniRef50_A7P4X0 Cluster: Chromosome chr4 scaffold_6, whole genom... 38 0.48
UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1; ... 37 0.64
UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus amyloliquef... 36 1.5
UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas palus... 34 4.5
UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2; ... 34 4.5
UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion s... 34 5.9
UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whol... 33 7.8
UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifi... 33 7.8
>UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor; n=144; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor - Homo sapiens
(Human)
Length = 359
Score = 243 bits (595), Expect = 4e-63
Identities = 111/151 (73%), Positives = 125/151 (82%)
Frame = +2
Query: 272 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 451
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 452 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 631
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 632 PNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
PNGA++GVAAQHSQCF AWY CPGLKV+ P
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSP 177
Score = 37.1 bits (82), Expect = 0.64
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +3
Query: 726 YSAXDAKGLLKAXIRDPXPVVMLEXEIXXG 815
+++ DAKGL+K+ IRD PVV+LE E+ G
Sbjct: 178 WNSEDAKGLIKSAIRDNNPVVVLENELMYG 207
>UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;
n=24; cellular organisms|Rep: Pyruvate dehydrogenase E1
beta subunit - Rhodopseudomonas palustris
Length = 469
Score = 194 bits (472), Expect = 4e-48
Identities = 94/145 (64%), Positives = 109/145 (75%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
VT+R+AL A+ EEM RD VFV+GEEVA+Y GAYKVT+GL +++GD+RVIDTPITE
Sbjct: 147 VTIREALRDAMAEEMRRDPDVFVMGEEVAEYQGAYKVTQGLLQEFGDRRVIDTPITEHGF 206
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
LKPI EFMTFNF+MQAID IINSAAKT YMS G + IVFRGPNGAAS
Sbjct: 207 AGVGVGAGFAGLKPIVEFMTFNFAMQAIDQIINSAAKTLYMSGGQLGCSIVFRGPNGAAS 266
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
VAAQHSQ + AWY+ PGLKV+ P
Sbjct: 267 RVAAQHSQDYSAWYAQIPGLKVVAP 291
Score = 52.0 bits (119), Expect = 2e-05
Identities = 25/45 (55%), Positives = 29/45 (64%)
Frame = +3
Query: 693 AXVQALKF*CLYSAXDAKGLLKAXIRDPXPVVMLEXEIXXGXHSQ 827
A + LK YSA DAKGLLKA IRDP PV+ LE E+ G H +
Sbjct: 281 AQIPGLKVVAPYSAADAKGLLKAAIRDPNPVIFLEHEMLYGQHGE 325
>UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=35; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Rickettsia
felis (Rickettsia azadi)
Length = 326
Score = 193 bits (471), Expect = 5e-48
Identities = 94/145 (64%), Positives = 109/145 (75%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+TVR+AL A+ EEM RD+KVFV+GEEVA+Y GAYKVT+GL +++G KRVIDTPITE
Sbjct: 3 ITVREALRDAMQEEMIRDDKVFVMGEEVAEYQGAYKVTQGLLEQFGPKRVIDTPITEYGF 62
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+PI EFMTFNF+MQA DHI+NSAAKT YMS G PIVFRGPNGAAS
Sbjct: 63 AGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQAKCPIVFRGPNGAAS 122
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
VAAQHSQ + A YS PGLKV+ P
Sbjct: 123 RVAAQHSQNYTACYSHVPGLKVVAP 147
Score = 38.3 bits (85), Expect = 0.28
Identities = 22/42 (52%), Positives = 24/42 (57%)
Frame = +3
Query: 699 VQALKF*CLYSAXDAKGLLKAXIRDPXPVVMLEXEIXXGXHS 824
V LK YSA D KGL+ IRD PV+ LE EI G HS
Sbjct: 139 VPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFLENEILYG-HS 179
>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Zymomonas mobilis
Length = 462
Score = 188 bits (458), Expect = 2e-46
Identities = 89/144 (61%), Positives = 107/144 (74%)
Frame = +2
Query: 293 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 472
T+R+AL A+ EEM RD++VFV+GEEVA+Y GAYKVT+GL +++G +RV+DTPI+E
Sbjct: 140 TLREALRDAMAEEMRRDDRVFVMGEEVAEYQGAYKVTQGLLQEFGARRVVDTPISEYGFS 199
Query: 473 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASG 652
L+P+ EFMT NFSMQAIDHIINSAAKT YMS G V PIVFRGPNGAA
Sbjct: 200 GIGVGAAMEGLRPVIEFMTMNFSMQAIDHIINSAAKTHYMSGGQVRCPIVFRGPNGAAPR 259
Query: 653 VAAQHSQCFGAWYSXCPGLKVLMP 724
V AQH+Q FG WY+ PGL VL P
Sbjct: 260 VGAQHTQNFGPWYAAVPGLVVLAP 283
Score = 40.7 bits (91), Expect = 0.052
Identities = 23/44 (52%), Positives = 24/44 (54%)
Frame = +3
Query: 684 PGTAXVQALKF*CLYSAXDAKGLLKAXIRDPXPVVMLEXEIXXG 815
P A V L Y A DAKGLLKA IR PVV LE E+ G
Sbjct: 270 PWYAAVPGLVVLAPYDAIDAKGLLKAAIRSDDPVVFLECELLYG 313
>UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, beta
subunit; n=1; Psychroflexus torquis ATCC 700755|Rep:
Pyruvate dehydrogenase E1 component, beta subunit -
Psychroflexus torquis ATCC 700755
Length = 325
Score = 157 bits (381), Expect = 4e-37
Identities = 71/147 (48%), Positives = 101/147 (68%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 463
+ + R+A+ +A+ EEM DE ++++GEEVA+Y+GAYK ++G+ ++G+KRVIDTPI+E
Sbjct: 2 RTIQFREAIVEAMSEEMRADETIYLMGEEVAEYNGAYKASKGMLDEFGEKRVIDTPISEL 61
Query: 464 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 643
+PI EFMTFNFS+ ID IIN+AAK MS G +PIVFRGP G+
Sbjct: 62 GFTGIGIGSAMNGNRPIIEFMTFNFSLVGIDQIINNAAKMRQMSGGQFNIPIVFRGPTGS 121
Query: 644 ASGVAAQHSQCFGAWYSXCPGLKVLMP 724
A + A HSQ F +W++ PGLKV++P
Sbjct: 122 AGQLGATHSQAFESWFANTPGLKVVIP 148
>UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaster
subgroup|Rep: CG11876-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 273
Score = 156 bits (379), Expect = 7e-37
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 2/127 (1%)
Frame = +2
Query: 245 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 421
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 422 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 598
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 599 GTVPVPI 619
G P+PI
Sbjct: 130 GDRPLPI 136
>UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit; n=1; Nitratiruptor
sp. SB155-2|Rep: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit - Nitratiruptor sp.
(strain SB155-2)
Length = 325
Score = 143 bits (347), Expect = 5e-33
Identities = 69/140 (49%), Positives = 91/140 (65%)
Frame = +2
Query: 299 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 478
R+ALN+AIDE M+ DE V +LGE+V +Y G+Y+V+ GL+ KYG KRVIDTPI E
Sbjct: 4 REALNRAIDESMKADESVVILGEDVGRYGGSYRVSEGLFAKYGPKRVIDTPIAELSIVGN 63
Query: 479 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVA 658
L+PI E MT NFS+ A+D I+N AAK YMS G + +P+ R P G + +A
Sbjct: 64 AIGMAIGGLRPIAEIMTVNFSLLAMDQIVNHAAKFRYMSGGKMTIPLTIRIPGGVSRQLA 123
Query: 659 AQHSQCFGAWYSXCPGLKVL 718
AQHS+ + Y+ PGL VL
Sbjct: 124 AQHSESYETLYASIPGLIVL 143
>UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, beta
subunit; n=7; Bacteria|Rep: Dehydrogenase complex, E1
component, beta subunit - Geobacter sulfurreducens
Length = 328
Score = 133 bits (321), Expect = 7e-30
Identities = 64/142 (45%), Positives = 87/142 (61%)
Frame = +2
Query: 299 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 478
RDALN A+ EEM RD V V GE+VA Y+G++KVTRGL ++G++RV DTPI+E
Sbjct: 7 RDALNLALKEEMRRDPSVVVWGEDVALYEGSFKVTRGLLAEFGEERVKDTPISENSIVGV 66
Query: 479 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVA 658
L+P+ E MT NF++ A+D I+N AK M G +P+V R P G S +
Sbjct: 67 AVGAAMGGLRPVAELMTVNFALLAMDQIVNHMAKIRSMFGGQTYLPMVVRAPGGGGSQLG 126
Query: 659 AQHSQCFGAWYSXCPGLKVLMP 724
AQHSQ ++ CPG+ V +P
Sbjct: 127 AQHSQSLETYFMHCPGIHVAVP 148
Score = 37.1 bits (82), Expect = 0.64
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +3
Query: 738 DAKGLLKAXIRDPXPVVMLEXEIXXGXHSQCXIKPSPXTLSSYWQTKVKR 887
DA+GLLKA IRD PV+ LE E+ +S+ + P ++ + + VKR
Sbjct: 153 DARGLLKAAIRDDNPVMFLEHELL--YNSKGEVPDDPESVIPFGKADVKR 200
>UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=6; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component beta subunit - Synechococcus
elongatus (Thermosynechococcus elongatus)
Length = 327
Score = 131 bits (317), Expect = 2e-29
Identities = 64/139 (46%), Positives = 83/139 (59%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
+AL AIDEEMERD VFVLGE+V Y G+YKVT+ L+KKYG+ R++DTPI E
Sbjct: 8 NALRAAIDEEMERDPTVFVLGEDVGHYGGSYKVTKDLYKKYGELRLLDTPIAENSFTGMA 67
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
L+PI E M F + A + I N+A Y S G +PIV RGP G + A
Sbjct: 68 IGAAMTGLRPIVEGMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPIVIRGPGGVGRQLGA 127
Query: 662 QHSQCFGAWYSXCPGLKVL 718
+HSQ A++ PGLK++
Sbjct: 128 EHSQRLEAYFQAVPGLKIV 146
>UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 327
Score = 128 bits (309), Expect = 2e-28
Identities = 63/145 (43%), Positives = 88/145 (60%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T R+A+ A+ EE+ERDE V VLGEEV Q+ GAYKV+ GL +K+G KR++DTPI+E
Sbjct: 4 LTYREAVRAALAEELERDENVVVLGEEVGQFHGAYKVSEGLLEKFGPKRIVDTPISEAGF 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
++P+ E M ++F A D I+N+AA YMS G + PIV RGP +
Sbjct: 64 IGLGVGASMLGIRPVMELMFWSFYSVAFDQILNNAANIRYMSGGQINCPIVIRGPANGGT 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
V A HS + PG+KV++P
Sbjct: 124 NVGATHSHTPENVLANHPGVKVVVP 148
>UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=25; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhizobium loti
(Mesorhizobium loti)
Length = 332
Score = 126 bits (305), Expect = 6e-28
Identities = 60/147 (40%), Positives = 90/147 (61%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 463
+ ++ A+ +A+ M+ DE+VF++GE++ Y GA++VT L ++YG +RVIDTPI+E
Sbjct: 6 RELSYAQAIQEAMAIAMDMDERVFLMGEDIGVYGGAFQVTGDLVERYGTERVIDTPISEL 65
Query: 464 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 643
++PI EF +F+ A++ I+N AAK +M G V VP+V R P G+
Sbjct: 66 GGAGVAVGAALTGMRPIFEFQFSDFATLAMEQIVNQAAKMRFMLGGEVSVPVVMRFPAGS 125
Query: 644 ASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+G AAQHSQ AW PGLKV+ P
Sbjct: 126 GTGAAAQHSQSLEAWLGHVPGLKVIQP 152
>UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=66; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Zygnema
circumcarinatum (Green alga)
Length = 325
Score = 121 bits (292), Expect = 2e-26
Identities = 56/143 (39%), Positives = 83/143 (58%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
V + +AL Q + EEM+RD +V V+GE+V Y G+YKVT+G ++YGD R++DTPI E
Sbjct: 4 VLLFEALRQGLQEEMDRDPRVMVMGEDVGHYGGSYKVTKGFAERYGDLRLLDTPIAENSF 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ E M F + A + I N+A Y S G +PIV RGP G
Sbjct: 64 TGMAIGAAMTGLRPVVEGMNMGFLLLAFNQIANNAGMLHYTSGGNFTIPIVIRGPGGVGR 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVL 718
+ A+HSQ +++ PGL+++
Sbjct: 124 QLGAEHSQRLESYFQSVPGLQMV 146
>UniRef50_A6UDY4 Cluster: Transketolase central region; n=1;
Sinorhizobium medicae WSM419|Rep: Transketolase central
region - Sinorhizobium medicae WSM419
Length = 325
Score = 121 bits (291), Expect = 3e-26
Identities = 60/145 (41%), Positives = 80/145 (55%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T RDAL +A+D+ M D + V+GEEV +Y GAY VT+ L K +G R+IDTPI+E
Sbjct: 5 MTYRDALRKALDDAMTDDSSIVVIGEEVGRYGGAYGVTKDLIKIHGADRLIDTPISEPAI 64
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ E M +F +D + N AAK YM G + VP+V R G
Sbjct: 65 VGTAVGAAMTGLRPVAELMYIDFLGMTMDQLANQAAKIRYMFGGQIGVPMVLRTQGGTGR 124
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
AQHSQ AW PGL++ MP
Sbjct: 125 SAGAQHSQSLEAWVMHTPGLRLAMP 149
>UniRef50_A5UU14 Cluster: Transketolase, central region; n=3;
Chloroflexi (class)|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 322
Score = 118 bits (285), Expect = 2e-25
Identities = 58/145 (40%), Positives = 86/145 (59%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+TVR+AL QA+ + M+ DE+VF++GE++ Y Y VT G ++YG +R+ D PI E
Sbjct: 4 ITVREALRQALHDAMQ-DERVFIIGEDIGHYGSTYGVTAGFLEQYGPERIRDAPIAESGI 62
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
++PI E M+ NFS+ A D + N AAK + M G + VP+V R NG
Sbjct: 63 VGIAIGAAMVGMRPIAEIMSVNFSLLAFDMLFNHAAKIYSMFGGQMTVPMVLRTTNGWTQ 122
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
++A HSQ F +++ PGLKV+ P
Sbjct: 123 -LSATHSQSFDVYFAHMPGLKVVAP 146
>UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=2; Rhodobacterales|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhodobacterales bacterium
HTCC2654
Length = 333
Score = 118 bits (284), Expect = 2e-25
Identities = 61/150 (40%), Positives = 86/150 (57%)
Frame = +2
Query: 275 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 454
+ + +T+ A+N+A+ EEM RDE VF+LGE+VA+ +KV GL +++G RVIDTPI
Sbjct: 1 MTMREITLSQAVNEALAEEMRRDETVFILGEDVAEAGTPFKVLSGLVEEFGTDRVIDTPI 60
Query: 455 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 634
+E +P+ + M +F +D + N AAK YMS G + VP+V R
Sbjct: 61 SEPGFVGLAVGAAMTGARPVVDLMFGDFLYLVMDQLCNQAAKQHYMSGGKLSVPMVLRTN 120
Query: 635 NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA AAQHSQ A + PGLKV +P
Sbjct: 121 LGATRRSAAQHSQSLQALVAHIPGLKVALP 150
>UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=39; Bacteria|Rep: 2-oxoisovalerate dehydrogenase
subunit beta - Bacillus subtilis
Length = 327
Score = 117 bits (281), Expect = 5e-25
Identities = 59/141 (41%), Positives = 83/141 (58%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
DA+N A+ EEMERD +VFVLGE+V + G +K T GL++++G++RV+DTP+ E
Sbjct: 8 DAINLAMKEEMERDSRVFVLGEDVGRKGGVFKATAGLYEQFGEERVMDTPLAESAIAGVG 67
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
++PI E +F M A++ II+ AAK Y S PIV R P G A
Sbjct: 68 IGAAMYGMRPIAEMQFADFIMPAVNQIISEAAKIRYRSNNDWSCPIVVRAPYGGGVHGAL 127
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
HSQ A ++ PGLK++MP
Sbjct: 128 YHSQSVEAIFANQPGLKIVMP 148
>UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component,
beta subunit; n=24; Streptococcus|Rep: Pyruvate
dehydrogenase (E1) component, beta subunit -
Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)
Length = 337
Score = 116 bits (279), Expect = 9e-25
Identities = 55/148 (37%), Positives = 87/148 (58%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
+K + +R+A+N A+ EEM +D +F++GE+V Y G + + G+ ++G+KRV DTPI+E
Sbjct: 9 TKLMALREAVNLAMSEEMRKDPDIFLMGEDVGIYGGDFGTSVGMLAEFGEKRVKDTPISE 68
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
L+PI + +F A+D I+N+ AK YM G + P+ FR +G
Sbjct: 69 AAIAGAAVGAAITGLRPIVDLTFMDFITIALDAIVNNGAKNNYMFGGGLKTPVTFRVASG 128
Query: 641 AASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+ G AAQHSQ +W + PG+KV+ P
Sbjct: 129 SGIGSAAQHSQSLESWLTHIPGIKVVAP 156
>UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta
subunit; n=3; Proteobacteria|Rep: Pyruvate dehydrogenase
complex E1 beta subunit - Thiobacillus ferrooxidans
(Acidithiobacillus ferrooxidans)
Length = 343
Score = 116 bits (278), Expect = 1e-24
Identities = 58/137 (42%), Positives = 78/137 (56%)
Frame = +2
Query: 314 QAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXX 493
+A DEEM RD VF +GE++ G YK T GL+ KYG++RVIDTPI+E
Sbjct: 12 RAHDEEMARDPLVFAMGEDIGVAGGTYKATSGLFAKYGEQRVIDTPISENSYTGIGVGAA 71
Query: 494 XXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQ 673
+PI E M+ NF+ A+D ++N+AAK YMS G + P V R P G A + AQHS
Sbjct: 72 MIGARPIVEIMSVNFAWLAMDQLMNNAAKIHYMSGGRIRCPFVMRVPGGTAHQLGAQHSA 131
Query: 674 CFGAWYSXCPGLKVLMP 724
+ GL+V+ P
Sbjct: 132 RMEKVFMGISGLRVVTP 148
>UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate
dehydrogenase (lipoamide) beta, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
pyruvate dehydrogenase (lipoamide) beta, partial -
Ornithorhynchus anatinus
Length = 141
Score = 115 bits (277), Expect = 2e-24
Identities = 51/57 (89%), Positives = 57/57 (100%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
VTVRDALNQA+DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTPI+E
Sbjct: 1 VTVRDALNQALDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISE 57
>UniRef50_Q3WCG4 Cluster: Transketolase, central
region:Transketolase, C terminal; n=7; Bacteria|Rep:
Transketolase, central region:Transketolase, C terminal
- Frankia sp. EAN1pec
Length = 351
Score = 115 bits (276), Expect = 2e-24
Identities = 59/145 (40%), Positives = 82/145 (56%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+R+ALN A+D+ + RDE+VF+LGE++A G+ T+GL KYG RV+DTPI+E
Sbjct: 21 MTMREALNLALDQALARDERVFLLGEDIAD-PGSSGPTKGLSTKYGADRVLDTPISEAAI 79
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
+P+ E M +F A D I+N AAK +M+ G PI R
Sbjct: 80 VGAAIGAAMEGFRPVAEIMIMDFIGIAADQIVNHAAKLRFMTGGRTTAPITVRTQVYGGL 139
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
G A HSQ AW+ PGLKV++P
Sbjct: 140 GTGATHSQSLEAWFMHVPGLKVIVP 164
>UniRef50_A5V539 Cluster: Transketolase, central region; n=4;
Bacteria|Rep: Transketolase, central region -
Sphingomonas wittichii RW1
Length = 324
Score = 115 bits (276), Expect = 2e-24
Identities = 54/140 (38%), Positives = 77/140 (55%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+N+A+D+ + D V +LGE++A G + VTRGL K+G RVID PI E
Sbjct: 9 AINRALDDALAADPSVLLLGEDIANAGGTFAVTRGLLDKHGPDRVIDMPIAENAIAGMAV 68
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
+P+ E M +F +D ++N AAK +M G VP+V R +G Q
Sbjct: 69 GLALGGFRPVVEIMFMDFMTLTMDALVNQAAKLHFMFGGQSAVPMVVRTQHGGGLNAGPQ 128
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
HSQC AW++ PGLKV++P
Sbjct: 129 HSQCLEAWFAHIPGLKVVVP 148
>UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium
cellulolyticum H10|Rep: Transketolase-like - Clostridium
cellulolyticum H10
Length = 346
Score = 113 bits (273), Expect = 5e-24
Identities = 56/154 (36%), Positives = 83/154 (53%)
Frame = +2
Query: 263 TSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 442
T + + ++ +DAL +A+D+ + RD +VF++GE V G + T+GL +KYG RV
Sbjct: 17 TDDSEIGRMISYKDALYEALDQSLARDPRVFIMGEGVDDPGGVFGTTKGLHEKYGRNRVF 76
Query: 443 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 622
DTPI E L+PI +F + ++D ++N AAK YM+ G V VP+V
Sbjct: 77 DTPIAENSLTGIAAGAAMAGLRPIFVHSRMDFLLLSLDQLVNHAAKWSYMTGGKVKVPLV 136
Query: 623 FRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
R + G AQHSQC PGLK+ +P
Sbjct: 137 VRTVSARGWGSGAQHSQCLHGMLMNAPGLKIAVP 170
>UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Transketolase,
central region - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 330
Score = 113 bits (272), Expect = 6e-24
Identities = 58/145 (40%), Positives = 78/145 (53%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
++ +AL +A+DEE+ RDE+ F +GE+V + G + GL +KYG +RV DTPI+E
Sbjct: 5 ISYTEALREALDEELGRDERTFFMGEDVGAFGGIFGEAAGLQQKYGKERVFDTPISETFI 64
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+PI E +F A+D I N AAK YM G VP+V P GA
Sbjct: 65 VGGGVGAAITGLRPIVELQFADFVSVAMDEIYNKAAKWRYMHGGLFKVPLVIIAPEGAMG 124
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
G +HSQC A + GL VL P
Sbjct: 125 GAGPEHSQCPEALFWSAAGLYVLTP 149
>UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit; n=13;
cellular organisms|Rep: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit - Geobacillus
kaustophilus
Length = 339
Score = 112 bits (270), Expect = 1e-23
Identities = 61/145 (42%), Positives = 81/145 (55%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T AL +AI EMERD VFV+GE+V Y G + T GL++K+G +RVIDTPI+E
Sbjct: 9 LTGNKALAEAIRLEMERDPNVFVMGEDVGVYGGIFGATEGLFQKFGPERVIDTPISETAF 68
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
++PI E M +F +D I N AK YMS G V +P+V G
Sbjct: 69 IGAAIGAAAEGMRPIVELMFVDFFGVCMDQIYNHMAKIPYMSGGRVKLPMVLMTAVGGGY 128
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
AAQHSQ A ++ PG+KV+ P
Sbjct: 129 SDAAQHSQTLYATFAHLPGMKVVAP 153
>UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, beta
subunit; n=1; marine gamma proteobacterium HTCC2080|Rep:
Acetoin dehydrogenase E1 component, beta subunit -
marine gamma proteobacterium HTCC2080
Length = 325
Score = 110 bits (264), Expect = 6e-23
Identities = 58/146 (39%), Positives = 79/146 (54%), Gaps = 1/146 (0%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXX 466
++VR+A+N + EEM RD +V ++GE+VA G Y VT GL +K+G RVIDTPITE
Sbjct: 3 MSVREAINLTLHEEMARDPRVVIMGEDVASGQGGVYGVTAGLTEKFGVARVIDTPITESA 62
Query: 467 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 646
L+P+ E M +F +D ++N AK YM G P+V R GA
Sbjct: 63 IVGAAGGAALTGLRPVAELMFIDFLGVCLDQLLNQIAKFRYMFGGQARTPLVIRTMIGAG 122
Query: 647 SGVAAQHSQCFGAWYSXCPGLKVLMP 724
G QHSQ + PG+KV+ P
Sbjct: 123 EGTGPQHSQILYPMLAAIPGIKVVAP 148
>UniRef50_A5V352 Cluster: Transketolase, central region; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase, central
region - Sphingomonas wittichii RW1
Length = 334
Score = 108 bits (260), Expect = 2e-22
Identities = 60/157 (38%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Frame = +2
Query: 260 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD--GAYKVTRGLWKKYGDK 433
AT A + A+N AI + ME D+ V VLGE+VA + G VT+GL ++GD
Sbjct: 2 ATQTAAKPAKANILQAINAAIADAMEADDNVVVLGEDVADPEEGGVCGVTKGLSSRFGDA 61
Query: 434 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 613
RV TPI+E KP+ E M NF+ A+D I+N AAK +MS G V
Sbjct: 62 RVRSTPISEQAIVGAAIGASLVGFKPVAEIMLMNFTTVAMDMIVNHAAKLRFMSGGQTHV 121
Query: 614 PIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
PIV R G QH AW++ G+KV+ P
Sbjct: 122 PIVIRTMTGTGFASGGQHCDYLEAWFAHTAGIKVVAP 158
>UniRef50_A1SN85 Cluster: Transketolase, central region; n=4;
cellular organisms|Rep: Transketolase, central region -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 347
Score = 108 bits (260), Expect = 2e-22
Identities = 58/148 (39%), Positives = 78/148 (52%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
S+ +T A+ +AI EMERD VF LGE+V Y G + T GL ++G RVIDTPI+E
Sbjct: 14 SRRLTTSKAIVEAIAFEMERDPSVFYLGEDVGSYGGIFGSTGGLLDRFGKDRVIDTPISE 73
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
++PI E M +F +D I N AK + S G V VP+V G
Sbjct: 74 TAFIGLGIGAAVEGMRPIVELMFADFMGVCLDQIYNHMAKIHFESGGNVKVPMVLTMAAG 133
Query: 641 AASGVAAQHSQCFGAWYSXCPGLKVLMP 724
AQHSQC ++ PG+KV++P
Sbjct: 134 GGYSDGAQHSQCLWGTFAHLPGMKVVVP 161
>UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=2;
Plasmodium falciparum|Rep: Pyruvate dehydrogenase beta
subunit - Plasmodium falciparum
Length = 415
Score = 108 bits (260), Expect = 2e-22
Identities = 55/141 (39%), Positives = 80/141 (56%)
Frame = +2
Query: 296 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 475
+ +AL+ AI EEM++D+ V+VLGE+V Y G+YKVT+ L +G RV+DTPI E
Sbjct: 94 ISEALHMAIYEEMKKDKGVYVLGEDVGLYGGSYKVTKNLAHFFGFSRVLDTPICENAFMG 153
Query: 476 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGV 655
L+PI E M +F + A + I N+A YM G +PIV RGP G +
Sbjct: 154 LGIGSAINDLRPIIEGMNLSFLILAFNQISNNACMMRYMCDGQFNIPIVIRGPGGIGKQL 213
Query: 656 AAQHSQCFGAWYSXCPGLKVL 718
+HSQ ++ PG+K++
Sbjct: 214 GPEHSQRIESYLMSIPGIKIV 234
>UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, beta
subunit; n=4; Bacilli|Rep: Acetoin dehydrogenase, E1
component, beta subunit - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 346
Score = 107 bits (257), Expect = 4e-22
Identities = 60/159 (37%), Positives = 86/159 (54%), Gaps = 12/159 (7%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKYG 427
+ +T A+N+AID+ ME+DE V ++G +V+ + G + VT+GL KKY
Sbjct: 5 RKLTFMGAINEAIDQSMEKDEDVILIGTDVSGGAKVDHIKDDDTFGGVFGVTKGLAKKYS 64
Query: 428 DKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTV 607
KRVIDTPI E L+PI E M +F +D I+N AK YM G
Sbjct: 65 RKRVIDTPIAEHITLSTAVGAAATGLRPIAELMFNDFIGFGLDPILNQGAKMRYMFGGKA 124
Query: 608 PVPIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+P+V R +GA + AAQHSQ ++ PG+KV++P
Sbjct: 125 KIPLVVRTVHGAGASAAAQHSQSLYNMFAAIPGVKVVVP 163
>UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2;
Actinobacteria (class)|Rep: Transketolase, central
region - Acidothermus cellulolyticus (strain ATCC 43068
/ 11B)
Length = 327
Score = 107 bits (257), Expect = 4e-22
Identities = 54/145 (37%), Positives = 77/145 (53%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
++ R+A+ + + +EM RD +V ++GE+V G +K T GL ++G RVIDTPI E
Sbjct: 4 LSYREAVARGLAQEMARDSRVVLIGEDVGAAGGVFKATVGLLDQFGPSRVIDTPIAEQAI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
++P+ E M +F D I N AKT YM+ G + +P+V R NG
Sbjct: 64 IGAAMGAAMNGMRPVAEIMFSDFFAVCWDQIANQIAKTRYMTHGQISLPLVIRTANGGGV 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
AQHSQ W PGLKV+ P
Sbjct: 124 RFGAQHSQSVENWAMMVPGLKVVAP 148
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 106 bits (254), Expect = 9e-22
Identities = 53/157 (33%), Positives = 83/157 (52%)
Frame = +2
Query: 254 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 433
++ A S+ +T A+ +A ++M RD + +LGE+V + G + +T+GL+ +G
Sbjct: 340 AYPAPPAAGSRKITYAQAITEAFAQQMARDPDLLILGEDVGRTGGIFGLTKGLFDTFGPD 399
Query: 434 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 613
RV DTPI+E + + E ++F +D I+N AAK +M G V
Sbjct: 400 RVRDTPISEGAIATCGVGAAMRGKRVVVEAQLWDFVTLMMDAIVNQAAKARFMLGGKAKV 459
Query: 614 PIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
PIVFRGP GA +AAQH Q ++ PGL++ P
Sbjct: 460 PIVFRGPQGAGIRLAAQHCQSLEMLFANVPGLEIYAP 496
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 105 bits (253), Expect = 1e-21
Identities = 60/181 (33%), Positives = 93/181 (51%), Gaps = 2/181 (1%)
Frame = +2
Query: 185 IIFKMALKSSPAVLGMLTRLSRRSFATSKALA--SKPVTVRDALNQAIDEEMERDEKVFV 358
++ ++ +P+ L + ++ KA A S+ ++ +A+N A+ E+E DE+ +
Sbjct: 311 LVLRVMASPAPSPADALQPIHGQTTEDRKARAPESRSMSYVEAVNAALRAELEEDERTVL 370
Query: 359 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 538
GE+V + G + +R L + +G RV DTPI E LKPI E M +F
Sbjct: 371 YGEDVGKSGGIFAASRYLQRDFGADRVFDTPIAENAILGSAVGAALGGLKPIVEIMWADF 430
Query: 539 SMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVL 718
A+D ++N AA Y++AG VP+V R GA G AQHSQ A + PGLKV
Sbjct: 431 IFVALDQLVNQAANVRYITAGKSSVPLVVRTQQGATPGSCAQHSQSIEAILAHVPGLKVA 490
Query: 719 M 721
+
Sbjct: 491 L 491
>UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit
(Lipoamide); n=1; Sulfolobus solfataricus|Rep: Pyruvate
dehydrogenase, beta subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 332
Score = 105 bits (253), Expect = 1e-21
Identities = 52/143 (36%), Positives = 77/143 (53%)
Frame = +2
Query: 296 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 475
+ A+ + I +EMER++++ VLGE+V + + T GL+ K+G KRVIDTPITE
Sbjct: 6 IAQAIAEGIRQEMERNDRIVVLGEDVTYWGAVFGFTMGLFDKFGRKRVIDTPITEQTFMG 65
Query: 476 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGV 655
L P+ M +F D + N AK +YMS G P+PI G G
Sbjct: 66 ISVGAASSGLHPVVSLMFVDFLGAGFDQMFNHMAKNYYMSGGQYPMPITVITAIGGGYGD 125
Query: 656 AAQHSQCFGAWYSXCPGLKVLMP 724
++QHSQ + ++ PG KV++P
Sbjct: 126 SSQHSQVLYSLFAHLPGFKVIVP 148
>UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=4; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Acholeplasma laidlawii
Length = 327
Score = 105 bits (252), Expect = 2e-21
Identities = 54/145 (37%), Positives = 73/145 (50%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ +A+NQAID+ ME+DE + V GE+ G ++VT GL KKYG+ RV DTPI E
Sbjct: 4 ITLLEAINQAIDQAMEKDESIVVFGEDAGFEGGVFRVTAGLQKKYGETRVFDTPIAESAI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
LKPI E F ++ AA+ S G VP+V R P+G
Sbjct: 64 VGSAVGMAINGLKPIAEIQFDGFIFPGYTDLVTHAARMRNRSRGQFTVPMVLRLPHGGGI 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
HS+ + PGLKV+ P
Sbjct: 124 RALEHHSEALEVLFGSIPGLKVVTP 148
>UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2;
Bacteria|Rep: Transketolase, central region - Comamonas
testosteroni KF-1
Length = 334
Score = 104 bits (250), Expect = 3e-21
Identities = 53/152 (34%), Positives = 83/152 (54%)
Frame = +2
Query: 269 KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 448
+A ++ ++ A+N A+ + + + GE+VA+ G + VT+ L K++G RV DT
Sbjct: 5 QATSTLALSYAKAINAALSRALTHMPETLLFGEDVAKPGGVFGVTKDLQKEFGSARVFDT 64
Query: 449 PITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 628
PI+E ++PI E M +FS+ A+D I+N AA Y+SAG + P+ R
Sbjct: 65 PISETAMLGTAVGAAMCGMRPIVEIMWIDFSLVAMDQIVNQAANVRYVSAGKLQAPMTIR 124
Query: 629 GPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA G AQHSQ A ++ PGL+V +P
Sbjct: 125 TQQGALPGSCAQHSQNLEAMFAHVPGLRVGLP 156
>UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03862 protein - Schistosoma
japonicum (Blood fluke)
Length = 91
Score = 104 bits (250), Expect = 3e-21
Identities = 46/74 (62%), Positives = 60/74 (81%)
Frame = +2
Query: 239 RLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWK 418
+L RS T+ ++ + +TVRDALN A+ EE+ERD+ V +LGEEVAQYDGAYK+T+GLWK
Sbjct: 17 QLCSRSIKTTSSVYTSKMTVRDALNSAMREELERDKDVIILGEEVAQYDGAYKITKGLWK 76
Query: 419 KYGDKRVIDTPITE 460
+GD RV+DTPITE
Sbjct: 77 TFGDSRVMDTPITE 90
>UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, beta
subunit; n=1; Beggiatoa sp. PS|Rep: Pyruvate
dehydrogenase, E1 component, beta subunit - Beggiatoa
sp. PS
Length = 362
Score = 101 bits (242), Expect = 3e-20
Identities = 54/149 (36%), Positives = 78/149 (52%)
Frame = +2
Query: 278 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 457
+ + +T A+ + + + ME+D V V+GE V + T GL +++G KRV D P+
Sbjct: 7 SQRELTYSQAILEGLRQCMEQDSSVIVIGEGVPDPKAIFGTTEGLLEQFGPKRVFDMPLA 66
Query: 458 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPN 637
E L+P+ +FS+ A+D IIN+AAK YM G V VP+V R
Sbjct: 67 ENGMTGICIGAALDGLRPVMVHQRIDFSLLALDQIINNAAKWHYMFDGAVSVPLVIRVLI 126
Query: 638 GAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
G G QHSQ A ++ PGLKV+MP
Sbjct: 127 GRGWGQGPQHSQSLQALFAHIPGLKVVMP 155
>UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=3;
Bacteria|Rep: Pyruvate dehydrogenase beta-subunit -
consortium cosmid clone pGZ1
Length = 333
Score = 100 bits (240), Expect = 5e-20
Identities = 56/145 (38%), Positives = 77/145 (53%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T A ++ M D V LGE++ + G + RGL + +G +RVIDTPI+E
Sbjct: 9 MTYSAAAAASLAAAMHADSSVVALGEDLGR-GGIFGQYRGLLEAFGPERVIDTPISEATI 67
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ E +F++ A+D I+N AAK YM G VP+V R P G S
Sbjct: 68 AGSAVGMALTGLRPVVEMRVVDFALCAMDEIVNQAAKNRYMFGGQGRVPMVIRMPIGIWS 127
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
AAQHSQ AW++ PGL VL P
Sbjct: 128 SSAAQHSQSLEAWFAHVPGLVVLCP 152
>UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Transketolase
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 325
Score = 100 bits (240), Expect = 5e-20
Identities = 58/147 (39%), Positives = 78/147 (53%), Gaps = 2/147 (1%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKV--TRGLWKKYGDKRVIDTPITEX 463
+T+ A+NQA+ EEM RD VF+ GE V A V T GL +++G RV DTP++E
Sbjct: 4 LTMGQAVNQALREEMLRDPNVFIAGEGVGVSIHAAPVLPTFGLLEEFGPDRVKDTPVSEA 63
Query: 464 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 643
L+P+ E M F A D I+N AAK Y+S G P+V R +GA
Sbjct: 64 AIAGLAVGASVMGLRPVVEIMFNPFVTLASDMIVNHAAKLRYLSGGKSTFPMVVRIKSGA 123
Query: 644 ASGVAAQHSQCFGAWYSXCPGLKVLMP 724
QHS AW + CPG++V+MP
Sbjct: 124 GFKAGCQHSHNLEAWLAHCPGIRVVMP 150
>UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=12; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 324
Score = 100 bits (240), Expect = 5e-20
Identities = 52/143 (36%), Positives = 76/143 (53%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ ALN+A+DEEM +D +V VLGE+V + G + VT GL +KYG RV+DTP++E
Sbjct: 4 MTMVQALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ E ++ D +++ AK Y S G P+V R P+G
Sbjct: 64 VGAALGMAAHGLRPVAEIQFADYIFPGFDQLVSQVAKLRYRSGGQFTAPLVVRMPSGGGV 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVL 718
HSQ A + GLKV+
Sbjct: 124 RGGHHHSQSPEAHFVHTAGLKVV 146
Score = 34.7 bits (76), Expect = 3.4
Identities = 18/30 (60%), Positives = 20/30 (66%)
Frame = +3
Query: 708 LKF*CLYSAXDAKGLLKAXIRDPXPVVMLE 797
LK + + DAKGLLKA IRD PVV LE
Sbjct: 143 LKVVAVSTPYDAKGLLKAAIRDEDPVVFLE 172
>UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5;
Bacteria|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 327
Score = 99.1 bits (236), Expect = 1e-19
Identities = 53/145 (36%), Positives = 76/145 (52%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T +A+ A+ + M D+++ VLGE+VA G + T GL ++G++RVID PI E
Sbjct: 4 MTFIEAIRSAMHDAMAADDRIIVLGEDVAVRGGVFLATEGLLARFGERRVIDMPIAECAI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L PI E ++ AID I+N AA+ Y S G PIV R P GA
Sbjct: 64 VGVAIGAALHGLLPIAEIQFADYIYPAIDQILNEAARLRYRSNGDWSCPIVVRAPFGAGI 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
A HSQ ++ PG+KV++P
Sbjct: 124 HGALYHSQSVERLFTSTPGIKVVIP 148
>UniRef50_A0H598 Cluster: Transketolase, central region; n=2;
Chloroflexus|Rep: Transketolase, central region -
Chloroflexus aggregans DSM 9485
Length = 343
Score = 99.1 bits (236), Expect = 1e-19
Identities = 51/148 (34%), Positives = 77/148 (52%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
++ +T +A+ A+ EM+RD +V ++GE++ Y GA+KVT+GL +++G+ +VIDTP+TE
Sbjct: 20 TRELTYLEAIRAALRYEMQRDLRVLIMGEDIGVYGGAFKVTQGLIEEFGEDQVIDTPMTE 79
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
P+ E +F D I+ AA + PVPI R P G
Sbjct: 80 LAMIYAAIGMSFEGFLPVVEMQFADFISTGFDAIVQFAATNHF--RWRQPVPITIRAPGG 137
Query: 641 AASGVAAQHSQCFGAWYSXCPGLKVLMP 724
HSQ AW+ PGLKV+ P
Sbjct: 138 GGLRAGPFHSQSNEAWFVHTPGLKVVAP 165
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 96.3 bits (229), Expect = 1e-18
Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 2/150 (1%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPIT 457
S+P +RDA+++A+ EEM RD V V GE+VA G + VTR L +K+G +R ++P+
Sbjct: 348 SEPKVMRDAISEALVEEMTRDSGVIVFGEDVAGDKGGVFGVTRNLTEKFGPQRCFNSPLA 407
Query: 458 EXXXXXXXXXXXXXXL-KPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 634
E + KP+ E ++ I+ + + A+ +Y SAG VP+V R P
Sbjct: 408 EATIIGTAIGMALDGIHKPVVEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAP 467
Query: 635 NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+G HSQ + + CPG+KV P
Sbjct: 468 SGGYIQGGPYHSQSIEGFLAHCPGIKVAYP 497
Score = 36.3 bits (80), Expect = 1.1
Identities = 17/23 (73%), Positives = 18/23 (78%)
Frame = +3
Query: 729 SAXDAKGLLKAXIRDPXPVVMLE 797
+A DAK LLKA IRDP PVV LE
Sbjct: 499 NAADAKALLKAAIRDPNPVVFLE 521
>UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 360
Score = 96.3 bits (229), Expect = 1e-18
Identities = 55/147 (37%), Positives = 83/147 (56%), Gaps = 7/147 (4%)
Frame = +2
Query: 200 ALKSSPAVLG---MLTR-LSRRSFATSKALASKP---VTVRDALNQAIDEEMERDEKVFV 358
+L SSP G ++T ++ ++ A++ + ASKP + + +AL + ++EEM+RD V V
Sbjct: 45 SLGSSPRSRGAQHLITNAVAAKADASATSTASKPGHELLLFEALREGLEEEMDRDPLVCV 104
Query: 359 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 538
+GE+V Y G+YKVT+GL KYGD RV+DTPI E L+PI E M F
Sbjct: 105 MGEDVGHYGGSYKVTKGLAAKYGDLRVLDTPIAENSFTGMGIGAAMTGLRPIIEGMNMGF 164
Query: 539 SMQAIDHIINSAAKTFYMSAGTVPVPI 619
+ A + I N+ Y S G +P+
Sbjct: 165 LLLAFNQISNNCGMLHYTSGGQFKIPV 191
>UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit beta; n=65; Bacteria|Rep:
Acetoin:2,6-dichlorophenolindophenol oxidoreductase
subunit beta - Bacillus subtilis
Length = 342
Score = 96.3 bits (229), Expect = 1e-18
Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 12/160 (7%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKY 424
++ +++ DA+N+A+ M +DE V ++GE+VA + G VT+GL +++
Sbjct: 2 ARVISMSDAINEAMKLAMRKDENVLLIGEDVAGGAAVDHLQDDEAWGGVLGVTKGLVQEF 61
Query: 425 GDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGT 604
G RV+DTPI+E L+PI E M +F D +IN AK YM G
Sbjct: 62 GRTRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCFDQVINQGAKFRYMFGGK 121
Query: 605 VPVPIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
VPI R GA AAQHSQ ++ PGLK ++P
Sbjct: 122 AQVPITVRTTYGAGFRAAAQHSQSLYGLFTSIPGLKTVVP 161
>UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) beta
subunit; n=24; Bacteria|Rep: Pyruvate dehydrogenase E1
(Lipoamide) beta subunit - Bacillus halodurans
Length = 328
Score = 95.5 bits (227), Expect = 2e-18
Identities = 48/150 (32%), Positives = 78/150 (52%)
Frame = +2
Query: 275 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 454
+ S+ T+ A+NQ +D+ + ++ V +LGE++ G ++ T GL++KYG RV+DTP+
Sbjct: 1 MGSQQQTMLQAINQTLDDLLATNDDVMLLGEDIGINGGVFRATDGLYEKYGKDRVVDTPL 60
Query: 455 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 634
E +PI E F + +I+ AA+ Y + G VP+V R P
Sbjct: 61 AESGIIGSAIGLAMNGKRPIVEIQFLAFIYPGFEQLISHAARMRYRTRGQYNVPMVIRTP 120
Query: 635 NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA HS+ A+++ PGLKV+ P
Sbjct: 121 YGAGIRGPELHSESVEAFFAHTPGLKVVAP 150
>UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=67; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Pseudomonas aeruginosa
Length = 350
Score = 94.3 bits (224), Expect = 4e-18
Identities = 51/145 (35%), Positives = 74/145 (51%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ AL A+D +ERD+ V V G++V + G ++ T GL KKYG RV D PI+E
Sbjct: 17 MTMIQALRSAMDIMLERDDDVVVFGQDVGYFGGVFRCTEGLQKKYGTSRVFDAPISESGI 76
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ E ++ A D +I+ AA+ Y SAG VP+ R P G
Sbjct: 77 IGAAVGMGAYGLRPVVEIQFADYVYPASDQLISEAARLRYRSAGDFIVPMTVRMPCGGGI 136
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
HSQ A ++ GL+ +MP
Sbjct: 137 YGGQTHSQSPEAMFTQVCGLRTVMP 161
>UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit, mitochondrial, putative; n=2; Trypanosoma
cruzi|Rep: 2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial, putative - Trypanosoma cruzi
Length = 368
Score = 93.9 bits (223), Expect = 5e-18
Identities = 50/141 (35%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+N A+D + RDEK V GE+VA + G ++ T L KKYG +RV D+P++E
Sbjct: 54 AINSALDLALSRDEKTVVFGEDVA-FGGVFRCTLNLSKKYGSQRVFDSPLSEQGLVGFAI 112
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 661
KPI E ++ A D I+N AAK + S G +V R P+ A
Sbjct: 113 GMASAGWKPIAEVQFADYIFPAFDQIVNEAAKMRFRSGGHFHCGGLVIRSPSSAVGHGGL 172
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
HSQ +++ C G+K++MP
Sbjct: 173 YHSQSVEGFFNHCAGIKIVMP 193
>UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular
organisms|Rep: Pyruvate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 338
Score = 93.9 bits (223), Expect = 5e-18
Identities = 48/148 (32%), Positives = 77/148 (52%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
++ +T+ +A+ + EM +D+ V VLGE+V + G ++ T L++++G+ RVIDTP+ E
Sbjct: 13 AQSLTLVEAIQDGLYTEMSQDDTVVVLGEDVGKNGGVFRATDQLYEEFGEDRVIDTPLAE 72
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
+KP+ E F A D I++ AA+ S G VP+V R P G
Sbjct: 73 AGIIGASIGLAQTGMKPVPEMQFMGFMYPAFDQIVSHAARLRSRSQGQYSVPMVIRAPYG 132
Query: 641 AASGVAAQHSQCFGAWYSXCPGLKVLMP 724
HS+ A++ PGLKV+ P
Sbjct: 133 GGIRAPEHHSESKEAFFVHEPGLKVVSP 160
Score = 35.1 bits (77), Expect = 2.6
Identities = 15/23 (65%), Positives = 18/23 (78%)
Frame = +3
Query: 738 DAKGLLKAXIRDPXPVVMLEXEI 806
DAKGLL A IRDP PV+ LE ++
Sbjct: 165 DAKGLLAASIRDPDPVIFLEPKL 187
>UniRef50_A0JY24 Cluster: Transketolase, central region; n=2;
cellular organisms|Rep: Transketolase, central region -
Arthrobacter sp. (strain FB24)
Length = 354
Score = 92.7 bits (220), Expect = 1e-17
Identities = 48/145 (33%), Positives = 73/145 (50%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
++++ ALN+A+DE + + K V GE+ + G +++T GL KYG RV DTP+ E
Sbjct: 24 LSMQQALNRALDEVLAGNPKSLVFGEDCGRLGGVFRITDGLQAKYGPGRVFDTPLAESGI 83
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
PI E F+ AI+ I+ A+ Y S GT+P+PI R P+
Sbjct: 84 LGMSVGLAMAGFHPIPEVQFDGFAYPAINQIVCQIARMNYRSRGTMPMPITLRVPSFGGI 143
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
H + A ++ PGLKV+ P
Sbjct: 144 RAPEHHGESLEALFAHVPGLKVVSP 168
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 91.9 bits (218), Expect = 2e-17
Identities = 53/142 (37%), Positives = 72/142 (50%), Gaps = 1/142 (0%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 478
D+LN A+ E D V ++GE++ Y GA+KV++GL KY D RV+ TPI+E
Sbjct: 342 DSLNNALHELFNEDGDVLLIGEDLLDPYGGAFKVSKGLSTKYPD-RVLTTPISEGGILGL 400
Query: 479 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVA 658
LKPI E M +F D ++N A+K +M V VP+V R P G G
Sbjct: 401 STGLAMRGLKPIAEIMFGDFLALGADQLLNHASKYQWMYNNKVEVPLVVRAPMGGKRGYG 460
Query: 659 AQHSQCFGAWYSXCPGLKVLMP 724
HSQ + PGL V+ P
Sbjct: 461 PTHSQSIEKMFFGIPGLTVVSP 482
>UniRef50_Q479Q1 Cluster: Transketolase, central
region:Transketolase, C-terminal precursor; n=2;
Rhodocyclaceae|Rep: Transketolase, central
region:Transketolase, C-terminal precursor -
Dechloromonas aromatica (strain RCB)
Length = 337
Score = 91.5 bits (217), Expect = 3e-17
Identities = 52/145 (35%), Positives = 72/145 (49%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ DA+ A+ EEM RD KV GE +A L ++G RV +TP+ E
Sbjct: 4 LTLNDAIGLALAEEMRRDHKVIAFGEGIATK------RHELVTEFGALRVRNTPLAEGII 57
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+P+ + + F A+D ++NSA K YMS G P+V GA
Sbjct: 58 AGTAAGAAAGGLRPVADLLFAPFLCYAMDELVNSAGKLRYMSGGQFSFPLVALAMTGAGW 117
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
GV AQH+ AW+ PGLKV+MP
Sbjct: 118 GVGAQHNHNVEAWFVHSPGLKVVMP 142
>UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1,
transketolase beta subunit; n=8; cellular organisms|Rep:
Pyruvate dehydrogenase complex E1, transketolase beta
subunit - Uncultured methanogenic archaeon RC-I
Length = 325
Score = 91.1 bits (216), Expect = 4e-17
Identities = 46/140 (32%), Positives = 71/140 (50%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+N A+ EM RD V V+GE+V + G ++ T GL +K+G +RV+DTP++E
Sbjct: 9 AVNDALMVEMGRDPSVIVMGEDVGKEGGVFRATTGLQEKFGRERVVDTPLSENGIIGTAI 68
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
+KP+CE F + +I A++ + G VP+V R P G
Sbjct: 69 GLALNGIKPVCEIQFSGFVYAGYEELIAHASRIRQRTMGRFSVPMVVRMPYGGGVKALEH 128
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
HS+ + + PGLKV+ P
Sbjct: 129 HSESYETIFLHDPGLKVVAP 148
>UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=33; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Staphylococcus
aureus
Length = 325
Score = 91.1 bits (216), Expect = 4e-17
Identities = 44/145 (30%), Positives = 69/145 (47%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ A+N A+ E++ D+ V + GE+V G ++VT GL K++G+ RV DTP+ E
Sbjct: 4 MTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
+P+ E F + D I A+T + S GT P+ R P G
Sbjct: 64 GGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGV 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
H+ + PGLKV++P
Sbjct: 124 HTPELHADNLEGILAQSPGLKVVIP 148
>UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=23; Mollicutes|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Mycoplasma
pneumoniae
Length = 327
Score = 89.8 bits (213), Expect = 9e-17
Identities = 50/141 (35%), Positives = 66/141 (46%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
+AL A+D +ERD V + G++ G ++ T+GL KKYG++RV D PI E
Sbjct: 11 EALGNAMDLALERDPNVVLYGQDAGFEGGVFRATKGLQKKYGEERVWDCPIAEAAMAGIG 70
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
LKPI E FS A+ I AA+ S G PI+ R P G
Sbjct: 71 VGAAIGGLKPIVEIQFSGFSFPAMFQIFTHAARIRNRSRGVYTCPIIVRMPMGGGIKALE 130
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
HS+ A Y GLK +MP
Sbjct: 131 HHSETLEAIYGQIAGLKTVMP 151
>UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18;
cellular organisms|Rep: Transketolase, central region -
Shewanella sp. (strain W3-18-1)
Length = 325
Score = 88.2 bits (209), Expect = 3e-16
Identities = 46/141 (32%), Positives = 72/141 (51%), Gaps = 1/141 (0%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+N+A+ M+ DE++ V GE+V + G ++ T GL +K+G R +TP+TE
Sbjct: 9 AVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRARCFNTPLTEQGIAGFAN 68
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 661
+ + E ++ A D I+N +AK Y S V +VFR P G
Sbjct: 69 GLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGH 128
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
HSQ A+++ PGLKV++P
Sbjct: 129 YHSQSPEAYFTQTPGLKVVVP 149
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 87.0 bits (206), Expect = 6e-16
Identities = 64/183 (34%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Frame = +2
Query: 179 SDIIFKMALKSSPAVLGMLTRLSRRSFATSKALASKPVTVR--DALNQAIDEEMERDEKV 352
+D I K S G T+L RS +T L S+ +R A+N+A E ME D+ +
Sbjct: 277 NDAIRKAKQARSSPFYGAETQLQSRS-STFHPLPSQGSKIRLSRAINKAFLEIMELDKNI 335
Query: 353 FVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMT 529
+GE+V A Y GA+K++ GL + ++ VI+TPI+E P E M
Sbjct: 336 LFIGEDVKAPYGGAFKISDGLSDSFPEQ-VINTPISESAIVGIGCGLAMHGYCPFVEIMF 394
Query: 530 FNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFGAWYSXCPGL 709
+F A D I+N AAK M V VP+V R P GA G HSQ + PGL
Sbjct: 395 GDFLTLAFDQILNHAAKFRDMYNDQVKVPLVIRTPMGAGRGYGPTHSQTLEKHFMGIPGL 454
Query: 710 KVL 718
+L
Sbjct: 455 TIL 457
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 87.0 bits (206), Expect = 6e-16
Identities = 45/143 (31%), Positives = 72/143 (50%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
DA++QA+ E +++ E + ++G+++A Y G +K+T G +++G R+ +TPI E
Sbjct: 372 DAISQALKESVKKHENLVLMGQDIADYGGVFKITEGFVEEFGKDRIRNTPICESAIVGAA 431
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
+K + E +F + I+N AK Y V V R P G G
Sbjct: 432 MGLSINGMKAMVEMQFSDFVSSGFNPIVNYLAKVKYRWDQNADV--VLRMPCGGGVGAGP 489
Query: 662 QHSQCFGAWYSXCPGLKVLMPLF 730
HSQ AW++ PGLKV+ P F
Sbjct: 490 FHSQTNEAWFTKVPGLKVIYPAF 512
>UniRef50_A7CXF2 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 398
Score = 86.6 bits (205), Expect = 8e-16
Identities = 47/153 (30%), Positives = 74/153 (48%)
Frame = +2
Query: 266 SKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVID 445
S A +T+ A+N A+ + + + +LG+++ Y GA+KVT L + +G RV +
Sbjct: 67 SLCTAPAHLTMAQAINAALRKILAERPESLLLGQDIGVYGGAFKVTENLLRDFGRTRVFN 126
Query: 446 TPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVF 625
TP+ E +PI EF +FS +A+ I +AA Y + VP+V+
Sbjct: 127 TPLAESACTGYATGLALGGYRPIEEFQFADFSTEAVTQITQNAATYHYRTGAAAKVPVVY 186
Query: 626 RGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
R P G V + HSQ + PG+K L P
Sbjct: 187 RFPCGGGITVGSFHSQELETLFLAFPGIKALYP 219
>UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=60; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Leifsonia xyli
subsp. xyli
Length = 337
Score = 86.2 bits (204), Expect = 1e-15
Identities = 42/140 (30%), Positives = 66/140 (47%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
ALN + + + D KV +LGE+V G ++VT GL ++G RV+DTP+ E
Sbjct: 22 ALNAGLRQALVADPKVLILGEDVGPLGGVFRVTEGLQSEFGASRVVDTPLAEAGIVGTAI 81
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
+P+ E F D I AK +G V +P+V R P+G G
Sbjct: 82 GLAMRGYRPVVEIQFNGFVFPGFDQITTQLAKMANRHSGAVSMPVVIRIPHGGHIGAVEH 141
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
H + A+++ GL+++ P
Sbjct: 142 HQEAPEAYFAHTAGLRIVAP 161
>UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=41; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Bacillus
subtilis
Length = 325
Score = 86.2 bits (204), Expect = 1e-15
Identities = 42/145 (28%), Positives = 67/145 (46%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+T+ A+ A+ E++ DE V V GE+V G ++ T GL K++G+ RV DTP+ E
Sbjct: 4 MTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGI 63
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
+P+ E F F + +D + A+ Y S G P+ R P G
Sbjct: 64 GGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWTSPVTIRSPFGGGV 123
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
H+ + PG+KV++P
Sbjct: 124 HTPELHADSLEGLVAQQPGIKVVIP 148
>UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2;
Bacteria|Rep: Transketolase-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 330
Score = 85.4 bits (202), Expect = 2e-15
Identities = 48/140 (34%), Positives = 74/140 (52%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+ + + + M D+ V V+GE+V + TRGL +++G +RV +TPI+E
Sbjct: 12 AMYEGLRDAMREDKTVVVIGEDVDR--SIIGATRGLIEEFGPERVRNTPISEATFVGACI 69
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
L+P+ + M +F A+D + N AAK YMS G V +PIV+ G + AAQ
Sbjct: 70 GASAAGLRPVVDLMVGSFFYVAMDQVANQAAKLPYMSGGQVSLPIVYFTATGPSGSAAAQ 129
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
HS+ GLK++MP
Sbjct: 130 HSENPHPMLMNVAGLKIVMP 149
Score = 34.3 bits (75), Expect = 4.5
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +3
Query: 684 PGTAXVQALKF*CLYSAXDAKGLLKAXIRDPXPVVMLEXEIXXGXHSQCXIKP 842
P V LK S DAKGL+ + IRDP PV+ L+ + G +P
Sbjct: 136 PMLMNVAGLKIVMPSSPCDAKGLMISAIRDPNPVIYLQDAVLGGTRGPVPEEP 188
>UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subunit;
n=9; Proteobacteria|Rep: Dehydrogenase, E1 component,
beta subunit - Coxiella burnetii
Length = 353
Score = 82.2 bits (194), Expect = 2e-14
Identities = 43/139 (30%), Positives = 67/139 (48%)
Frame = +2
Query: 308 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXX 487
+N A+ + M+ D V G + + T GL +++G+ RV D P E
Sbjct: 10 INAALRKAMQIDPSVLCYGLGINDSARIFGTTTGLVEEFGEDRVFDMPTAENAMTGVGIG 69
Query: 488 XXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQH 667
+P+ +F++ ++D IIN AAK + + AGT+PVP+ R G G H
Sbjct: 70 LAINGFRPVLSHCRLDFALLSLDQIINGAAKWYSLFAGTMPVPLTIRAIVGRGWGQGPTH 129
Query: 668 SQCFGAWYSXCPGLKVLMP 724
Q A ++ PGLKV+MP
Sbjct: 130 CQSLQACFAHIPGLKVVMP 148
>UniRef50_A5V556 Cluster: Transketolase domain protein; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase domain
protein - Sphingomonas wittichii RW1
Length = 330
Score = 82.2 bits (194), Expect = 2e-14
Identities = 47/144 (32%), Positives = 75/144 (52%)
Frame = +2
Query: 293 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 472
T +A+ QA EEM RDE+VF++GE++ + T G +G +RV DTPI+E
Sbjct: 5 TFLEAIRQAQYEEMTRDERVFIMGEDIIC--NVFGTTTGFVDAFGTERVRDTPISENGFI 62
Query: 473 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASG 652
++PI + +F A+D I++ AK+ Y+ G +P+V R +
Sbjct: 63 GAAGGAAMVGMRPIVDATISSFLYPAMDQIMSIIAKSRYIYGGQARLPLVIRSCLFYGNS 122
Query: 653 VAAQHSQCFGAWYSXCPGLKVLMP 724
AAQHS + + PGLK+++P
Sbjct: 123 NAAQHSDRNYSMFMNVPGLKIMVP 146
>UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase
beta-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase beta-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 344
Score = 81.0 bits (191), Expect = 4e-14
Identities = 48/147 (32%), Positives = 68/147 (46%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 463
+ +T A+++A + ME D + + G+ V Y G Y T + ++G RVID P E
Sbjct: 2 RSLTYSQAISEATVQCMEADPAIVLAGQSVDDYKGVYGTTGEAFARFGSARVIDIPNGEN 61
Query: 464 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 643
L+P+ +F A+D +IN AAK YM G VP+V RG G
Sbjct: 62 AFAGIAIGAATMGLRPLLVHTRDDFMFLAMDALINLAAKWRYMYGGKRGVPVVSRGVVGR 121
Query: 644 ASGVAAQHSQCFGAWYSXCPGLKVLMP 724
G A HSQ + + PGL V P
Sbjct: 122 GWGQGATHSQSLQSLFGHFPGLHVATP 148
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 80.2 bits (189), Expect = 7e-14
Identities = 51/151 (33%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
Frame = +2
Query: 275 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTP 451
LA KPVT+ DA+N + EEMER+ K+ + GE++A G + VTRGL RV + P
Sbjct: 68 LAEKPVTMIDAINHGLREEMERNPKIVMWGEDIADPKGGVFGVTRGLSSAL-PGRVFNAP 126
Query: 452 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 631
+ E KPI E +++ A + N A + S GT P+V R
Sbjct: 127 LAEASIAGVAAGMAIAGYKPIIEIQFADYTWPAFMQLRNEIATVRWRSQGTWNCPVVVRI 186
Query: 632 PNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA HS C ++ PG +VL P
Sbjct: 187 AAGAYIKGGPWHSACVEGVFAHIPGWRVLFP 217
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 79.8 bits (188), Expect = 9e-14
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 13/170 (7%)
Frame = +2
Query: 254 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD------------GAYK 397
+F P+T+ D +N + EEM R+ + V GE+VA G +K
Sbjct: 346 AFHAEPRFQGAPMTMVDLINATLREEMRRNPDILVFGEDVADASREQNLTEVKGKGGVFK 405
Query: 398 VTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAA 577
VT GL ++G +R + PI E LKP+ E F++ A+ + + A
Sbjct: 406 VTHGLQSEFGARRAFNAPIAEAAIVGRAIGMAARGLKPVAEIQFFDYIWPAMMQLRDELA 465
Query: 578 KTFYMSAGTVPVPIVFRGP-NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+ S G P + R P G +G A HSQC + ++ PGL+V+ P
Sbjct: 466 TMRWRSNGAFSAPAIIRVPIGGYLNGGAIYHSQCGESIFTHIPGLRVVFP 515
>UniRef50_A1G854 Cluster: Transketolase, central region; n=3;
Actinomycetales|Rep: Transketolase, central region -
Salinispora arenicola CNS205
Length = 321
Score = 79.8 bits (188), Expect = 9e-14
Identities = 45/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
++ R ALN+A+ +E+ RDE+VF+LGE++ A VT GL K++G +RV DTP++E
Sbjct: 4 LSYRKALNRALADELARDEEVFLLGEDIRV--AASAVTAGLLKRFGPERVRDTPLSEQAF 61
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 646
+P+ EF + I+N A K M+ G VP+ + P +G+
Sbjct: 62 TSFATGAAMAGARPVVEFQIPALLFLVFEQIVNHAHKFPLMTGGQCSVPVTYLVPGSGSR 121
Query: 647 SGVAAQHS 670
+G A QHS
Sbjct: 122 TGWAGQHS 129
>UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16;
Bacilli|Rep: E1 component beta subunit - Lactobacillus
reuteri
Length = 325
Score = 79.4 bits (187), Expect = 1e-13
Identities = 41/140 (29%), Positives = 63/140 (45%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+ + ID + D K V GE+V + G ++ T GL +KYG RV TP+ E
Sbjct: 9 AITEGIDIALAEDPKTLVFGEDVGKNGGVFRATNGLQEKYGVDRVFSTPLAESGILGMSM 68
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
+P+ E F+ +A+D I ++ + GT PI R P G + A
Sbjct: 69 GLAVTGWRPVPEIQFMGFTFEAMDSIAAQMSRIRFQYNGTKHAPITIRTPYGGGTHTAEL 128
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
H ++ PGL+V+ P
Sbjct: 129 HGDDLENFFVGIPGLRVVAP 148
>UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 329
Score = 77.8 bits (183), Expect = 4e-13
Identities = 48/147 (32%), Positives = 69/147 (46%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 463
K T A+ A + ++ +VFV+G+ + + L K +G KR+IDTP++E
Sbjct: 2 KKFTYSTAILDAYNFLLKNYPEVFVIGQGLWSPWYVGNTMKDLDKNFGKKRIIDTPVSEA 61
Query: 464 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 643
+KPI +F M A+D IIN AAK YM G I RG
Sbjct: 62 AVTGAAVGASLNEMKPIVVHPRMDFMMYAMDPIINQAAKWSYMFGGQSSPSITIRGIINR 121
Query: 644 ASGVAAQHSQCFGAWYSXCPGLKVLMP 724
AQHSQ + ++ PGLKV++P
Sbjct: 122 GGEQGAQHSQALHSLFAHIPGLKVVLP 148
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 77.8 bits (183), Expect = 4e-13
Identities = 44/142 (30%), Positives = 72/142 (50%), Gaps = 1/142 (0%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 478
D +++ + ME+ + +FVLGE+V + G TRG+ +++ D R++ TPI E
Sbjct: 418 DVISEVMLRNMEKFDGLFVLGEDVHRLRGGTAGATRGIAERFPD-RLLGTPICENGFTGM 476
Query: 479 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVA 658
+P+ E M +FS+ A D + N AK +M G PVP+V R +G
Sbjct: 477 ALGAALNGARPVVEIMYPDFSLVAADQLFNQIAKVRHMFGGDFPVPVVVRSRVTQGTGYG 536
Query: 659 AQHSQCFGAWYSXCPGLKVLMP 724
+QHS ++ PG +V+ P
Sbjct: 537 SQHSMDASGLFTLYPGWRVVAP 558
>UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor; n=84; cellular
organisms|Rep: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor - Homo sapiens (Human)
Length = 392
Score = 77.4 bits (182), Expect = 5e-13
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 1/141 (0%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 661
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
HSQ A+++ CPG+KV++P
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIP 215
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 77.0 bits (181), Expect = 6e-13
Identities = 49/148 (33%), Positives = 76/148 (51%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
+K +RDA+ +A+ ++ D + GE++ + GA+ V RGL + R+ +T I+E
Sbjct: 473 AKVFNLRDAIFEALIDKFYTDPTLISYGEDLRDWGGAFAVYRGLTESLPYHRLFNTSISE 532
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
+ + E M +F +A D I N AK MSAGT+ +P+V R G
Sbjct: 533 GAIVGSAVGYGMCGGRVVVEIMYCDFIGRAGDEIFNQLAKWQAMSAGTLKMPVVVRVSVG 592
Query: 641 AASGVAAQHSQCFGAWYSXCPGLKVLMP 724
+ G AQHSQ + + S PGLKV+ P
Sbjct: 593 SKYG--AQHSQDWSSIVSHIPGLKVVFP 618
>UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Transketolase domain protein - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 327
Score = 77.0 bits (181), Expect = 6e-13
Identities = 45/150 (30%), Positives = 73/150 (48%)
Frame = +2
Query: 275 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 454
++S+ + A+ + EEM RD+ +F++G+ V G + + +GL ++G+ RV+D I
Sbjct: 1 MSSETMGYNAAMGLGLVEEMRRDDSIFIMGQGVVT-GGWFGMEKGLVAEFGNDRVLDCGI 59
Query: 455 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 634
E +KP+ +F++ A D I + AK YM VP+ V P
Sbjct: 60 AEAFEAGLAAGAAIAGMKPVINMGFGDFALIAGDEIYHKLAKWRYMHGLDVPMTAVIIFP 119
Query: 635 NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA G +HS C PGLKV++P
Sbjct: 120 IGAMGGAGPEHSSCTEVLGMHFPGLKVVVP 149
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 75.8 bits (178), Expect = 1e-12
Identities = 46/138 (33%), Positives = 64/138 (46%), Gaps = 1/138 (0%)
Frame = +2
Query: 308 LNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
+ +D M D+++ +LGE++ Y GA+KVT GL Y RV +TPI+E
Sbjct: 326 IRAGLDAAMAADDRLLLLGEDICSPYGGAFKVTSGLSDSYPG-RVFNTPISEAGLVGVGA 384
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
+ + E M +F D +IN AAK M V VP++ R P G G
Sbjct: 385 GLALAGRRVVAEIMFGDFLTLVADQLINHAAKFTQMYGEDVEVPLLVRTPMGGRRGYGPT 444
Query: 665 HSQCFGAWYSXCPGLKVL 718
HSQ + PGL VL
Sbjct: 445 HSQSLETHFFGVPGLTVL 462
>UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=16; Ascomycota|Rep: Pyruvate dehydrogenase E1
component beta subunit - Sclerotinia sclerotiorum 1980
Length = 403
Score = 74.5 bits (175), Expect = 3e-12
Identities = 43/150 (28%), Positives = 73/150 (48%), Gaps = 2/150 (1%)
Frame = +2
Query: 281 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 460
+K + + ++N A+ + +DE V GE+V + G ++ + GL ++YG +RV +TP+ E
Sbjct: 76 TKRMNLFQSINDALSLALSKDETTMVFGEDVG-FGGVFRCSTGLAEQYGSERVFNTPLCE 134
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSA--GTVPVPIVFRGP 634
+K + E ++ A D ++N AAK Y G + R P
Sbjct: 135 QGIIGFAIGAAAEGMKAVAEIQFADYVYPAFDQLVNEAAKWRYRDGEYGRGLGGLTVRMP 194
Query: 635 NGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
GA A HSQ + ++ PGL+V+MP
Sbjct: 195 CGAVGHGALYHSQSPESLFTHIPGLRVIMP 224
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 74.1 bits (174), Expect = 5e-12
Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 15/159 (9%)
Frame = +2
Query: 293 TVRDALNQAIDEEMERDEKVFVLGEEVA-----QY---------DGAYKVTRGLWKKYGD 430
T+ D +N + +EM+RD ++ + GE+VA +Y G +K+T GL +YG
Sbjct: 397 TMADLINACLKDEMKRDPRIVIFGEDVADCSREEYLKQKQVKGKGGVFKLTSGLQMEYGA 456
Query: 431 KRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVP 610
RV ++P+ E LKP+ E F++ A+ + N + S G
Sbjct: 457 DRVFNSPLAEANIVGRATGMAVRGLKPVVEIQFFDYIWPAMHQLRNELPVVRWRSNGAFS 516
Query: 611 VPIVFR-GPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
P V R G +G A HSQC + ++ PG++V+ P
Sbjct: 517 SPAVIRVAIGGYLTGGAIYHSQCGESIFTHTPGMRVIFP 555
>UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta
subunit; n=1; Streptomyces coelicolor|Rep: Putative
pyruvate dehydrogenase beta subunit - Streptomyces
coelicolor
Length = 337
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/139 (31%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
Frame = +2
Query: 296 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 472
V + LN A+ + +++GE+VA Y GA+KVTRGL ++ D RV+ +P++E
Sbjct: 7 VAENLNSALHHLLGAHPGTYLIGEDVADPYGGAFKVTRGLSDRFPD-RVLSSPLSEGGIA 65
Query: 473 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASG 652
+ + E M +F+ A D ++N AAK+ M VP+ +V R P G G
Sbjct: 66 GVGAGLALAGNRSVVEMMFSDFAALAFDPLLNFAAKSVSMYGRRVPMSMVVRCPTGGNRG 125
Query: 653 VAAQHSQCFGAWYSXCPGL 709
HSQ + P L
Sbjct: 126 YGPTHSQSLQKHFLGIPSL 144
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 70.9 bits (166), Expect = 4e-11
Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 2/143 (1%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 478
D + + ME DE+V VLGE+V + G TRGL Y D RV+ TPI+E
Sbjct: 403 DTVADVMARRMETDERVVVLGEDVHRLKGGTNGATRGLSADYPD-RVLGTPISENAFTGI 461
Query: 479 XXXXXXXX-LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGV 655
+ P+ EFM +F A D + N K +M G +P+V R +G
Sbjct: 462 AGGMAADGRVLPVIEFMYPDFMWVAADQVFNQIGKARHMFGGDSDMPVVLRTKVAMGTGY 521
Query: 656 AAQHSQCFGAWYSXCPGLKVLMP 724
+QHS ++ PG +++ P
Sbjct: 522 GSQHSMDPAGIFATAPGWRIVAP 544
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 67.3 bits (157), Expect = 5e-10
Identities = 43/141 (30%), Positives = 64/141 (45%), Gaps = 1/141 (0%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXXX 481
A + + ME+D + V+GE+V ++ G TR + + D RV+ PI E
Sbjct: 407 AASDVLGRAMEKDPTIIVIGEDVHRFAGGVSGFTRNALELFPD-RVLAMPIAENGFTGVV 465
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
L+P+ E M +F A D I N +K +M PVPIV R +G +
Sbjct: 466 LGAALRGLRPVVEIMFGDFCFVAADQIANGISKVRHMFGDGFPVPIVMRVRVSPHTGYGS 525
Query: 662 QHSQCFGAWYSXCPGLKVLMP 724
QHS A + PG +V+ P
Sbjct: 526 QHSGDPSALFGMFPGWRVVSP 546
>UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit; n=1; Nostoc punctiforme
PCC 73102|Rep: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit - Nostoc punctiforme PCC
73102
Length = 343
Score = 66.9 bits (156), Expect = 7e-10
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = +2
Query: 296 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 472
V + LN+A+ D +VF++GE++ Y GA+KV +GL Y D RV+ TPI+E
Sbjct: 11 VVENLNRALHHIFAVDPQVFLIGEDILDPYGGAFKVGKGLSSNYPD-RVLTTPISEEAIV 69
Query: 473 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASG 652
KPI E M +F D I+N A+K+ M + + ++ R G G
Sbjct: 70 GIGGGLALCGNKPIIEIMFGDFIALGFDQILNFASKSVSMYGTKLDLNMIVRCAVGGNRG 129
Query: 653 VAAQHSQCFGAWYSXCPGL 709
HSQ + P L
Sbjct: 130 YGPTHSQSLQKHFVGIPNL 148
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 65.7 bits (153), Expect = 2e-09
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
++N ++ +E + K ++GE++ A Y GA+K T+ L + RV +TPI+E
Sbjct: 330 SINLSLQSLLENNSKAVIIGEDIEAPYGGAFKATKDLSTLFPG-RVKNTPISEGAITGVG 388
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
P+ E M +F D ++ A K M + VP++ R P G G
Sbjct: 389 IGLALSGFLPVVEIMFGDFMTLTFDQLLQHAGKFCEMYGKDLDVPLIIRTPMGGRRGYGP 448
Query: 662 QHSQCFGAWYSXCPGLKVL 718
HSQ ++ P L+V+
Sbjct: 449 THSQSLEKFFLGIPNLEVI 467
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 65.3 bits (152), Expect = 2e-09
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Frame = +2
Query: 269 KALASKP--VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 442
+A+ + P +++ DA+N AI EEM RD E++ Q +Y + + +G R
Sbjct: 496 RAMCTDPRGISIGDAVNLAILEEMLRDPTTVAHAEDL-QAGSSYNIPANTQQAFGTLRAA 554
Query: 443 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 622
D I E +PI E M NF + + + +SA T+ + G +P+
Sbjct: 555 DEIIDEGHFMGKALGEAMNGYRPIVELMNANFGIYGMAEL-SSAGNTYATTGGQFKMPMT 613
Query: 623 FRGPNGAA--SGVAAQHSQCFGAWYSXCPGLKV 715
G G A + A+HSQ F A+ PGLK+
Sbjct: 614 VIGAGGTAPNQSLGAEHSQPFHAYIMGIPGLKI 646
>UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha and Beta Fusion; n=6; cellular organisms|Rep:
(Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta
Fusion - Dokdonia donghaensis MED134
Length = 693
Score = 64.5 bits (150), Expect = 4e-09
Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 1/146 (0%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPITEXX 466
V + D A++E M + + + G++V + G ++ L +K+GD RV +TPI E
Sbjct: 357 VVMVDCALFAVEELMRKHPECLMYGQDVGGRLGGVFREAATLAQKFGDNRVFNTPIQEAF 416
Query: 467 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 646
LKPI E ++ ++ + +++ Y+S G PV ++ R P GA
Sbjct: 417 IVGSTVGMSAVGLKPIVEVQFADYIWPGLNQLFTEVSRSCYLSNGKWPVSMILRVPIGAY 476
Query: 647 SGVAAQHSQCFGAWYSXCPGLKVLMP 724
HS + + GLK+ P
Sbjct: 477 GSGGPYHSSSVESVVTNIRGLKIAYP 502
>UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit; n=1; Plesiocystis
pacifica SIR-1|Rep: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit - Plesiocystis
pacifica SIR-1
Length = 757
Score = 61.7 bits (143), Expect = 3e-08
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
+++ A+ A+ + +E + ++ G++VA+ G + T+GLW+++ +V D PI E
Sbjct: 374 ISLNGAIRAAMRDILESNPMAWIYGQDVAERGGVMQATKGLWERF-PSQVRDAPINEPLI 432
Query: 470 XXXXXXXXXXX-LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 646
+ E ++S+ + +++ + S GTV ++ R P
Sbjct: 433 LGTAVGYAMHEGATALPEIQFSDYSLNTLHWLVH-LGNLLWTSNGTVKANVIVRLPVEPL 491
Query: 647 SGVAAQHSQCFGAWYSXCPGLKVLMPLFSK 736
G + HS C +Y+ PGL +L P S+
Sbjct: 492 HGGSVYHSMCMEGFYAAIPGLTILAPTTSR 521
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 60.9 bits (141), Expect = 5e-08
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
A+NQ +DE + + V + GE++ G + TRGL +Y D RVI+ P++E
Sbjct: 348 AVNQVLDEALSQHPNVLIFGEDIEDPKGGVFGFTRGLSTRYPD-RVINAPLSEATIIGSS 406
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA-ASGVA 658
+PI E +F ++ + + + + G P+V P GA G
Sbjct: 407 VGLSASGWRPIVELQFIDFVGLGLNQLQSQLGTLSWRTVGKWRCPVVIYAPYGAYLPGGG 466
Query: 659 AQHSQCFGAWYSXCPGLKVLMP 724
HSQ + PG+ VL+P
Sbjct: 467 IWHSQSSDGILAHIPGINVLVP 488
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 58.0 bits (134), Expect = 3e-07
Identities = 37/113 (32%), Positives = 51/113 (45%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
VTV A+N+A+ + + + V GE+VA+ G Y VTRGL +K G RV DT + E
Sbjct: 386 VTVAQAVNRALADALAHHPEALVFGEDVARKGGVYGVTRGLQQKAGPARVFDTLLDEQAI 445
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 628
L PI E + A D I AA + + P+V R
Sbjct: 446 LGLALGAGVSGLLPIPEIQYLAYFHNAADQIRGEAATLQFFADRQYRNPMVVR 498
>UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 391
Score = 58.0 bits (134), Expect = 3e-07
Identities = 47/171 (27%), Positives = 71/171 (41%), Gaps = 22/171 (12%)
Frame = +2
Query: 278 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 457
A K V + A+NQA+ ++ D + +V GE+V + G ++ T GL ++G RV +TP+
Sbjct: 46 AGKEVNLFTAINQALHIALDTDPRSYVFGEDVG-FGGVFRCTTGLADRFGRNRVFNTPLC 104
Query: 458 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAID---------------------HIINSA 574
E + I E ++ A D I+N A
Sbjct: 105 EQGIAGFAVGLAAMGNRAIAEIQFADYIFPAFDQACLRLDQCFVPTYLYIQLLVQIVNEA 164
Query: 575 AKTFYMSAGTVPV-PIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLKVLMP 724
AK Y S + R P GA HSQ A++ PGLKV++P
Sbjct: 165 AKFRYRSGNEFNCGGLTIRSPYGAVGHGGHYHSQSPEAFFCHVPGLKVIIP 215
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/148 (27%), Positives = 63/148 (42%), Gaps = 2/148 (1%)
Frame = +2
Query: 287 PVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXX 466
P+T+ ++N A+ + + ++ V GE+V G Y VT+GL +++G RV DT + E
Sbjct: 464 PLTLAQSINAALADGLLEHPRMAVFGEDVGAKGGVYGVTKGLRERFGAARVFDTLLDETS 523
Query: 467 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA- 643
+ P+ E + A D + AA + S G P+V R A
Sbjct: 524 ILGLGLGAGLAGMLPVPEIQYLGYLHNAEDQLRGEAATMQFFSQGAYRNPMVVRIAGLAY 583
Query: 644 ASGVAAQ-HSQCFGAWYSXCPGLKVLMP 724
G H+ A PGL V +P
Sbjct: 584 QQGFGGHFHNDNSVAVLRDVPGLVVAVP 611
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 52.8 bits (121), Expect = 1e-05
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Frame = +2
Query: 293 TVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
T+ +A+N+A+ +E D + + GE++ G + T+GL G R+ ++P+ E
Sbjct: 357 TMVEAVNRALRTGLENDPTLVLFGEDIEDPKGGVFGFTKGLGTLAGP-RMTNSPLAEATI 415
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 646
++P+ E +F+ A + I + + +A P+V P G
Sbjct: 416 VGAAVGLAAAGMRPVVELQFVDFAGPAWNQIASQLTTLRWRTASAWRCPVVIYAPWGGYL 475
Query: 647 SGVAAQHSQCFGAWYSXCPGLKVLMP 724
G HSQ + ++ PGL+V++P
Sbjct: 476 PGGGIWHSQSNESLFTHLPGLRVVVP 501
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 52.4 bits (120), Expect = 2e-05
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +2
Query: 284 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITE 460
+ T+ A+NQ + E ++ ++ + G+++ G + T+GL ++ +RV ++P+ E
Sbjct: 333 RTTTMVAAINQTLREALQLYPQMIMFGQDIEDPKGGVFGFTKGLSSQFS-QRVTNSPLAE 391
Query: 461 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 640
KP+ E +F A + ++ A + S G P+V P G
Sbjct: 392 ATIVGVAAGLAATGYKPVFELQFIDFITPAFNQLVQQIATLRWRSQGDWSCPMVLYAPYG 451
Query: 641 A-ASGVAAQHSQCFGAWYSXCP 703
A G + HSQ W++ P
Sbjct: 452 AYLPGGSTWHSQSNEGWWTHIP 473
>UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=20; cellular organisms|Rep: Acetoin
dehydrogenase (TPP-dependent) beta chain - Polaribacter
irgensii 23-P
Length = 817
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/145 (24%), Positives = 58/145 (40%)
Frame = +2
Query: 290 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 469
V R + D +++ +V + GE+ + GL +KYGD RV DT I E
Sbjct: 483 VDARVVMRDNFDALLKKHPEVIIFGEDAGFIGDVNQGLEGLQEKYGDIRVSDTGIREATI 542
Query: 470 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 649
L+PI E ++ + A+ + + A Y S G P++ R
Sbjct: 543 IGQGIGLAMRGLRPIAEIQYLDYLLYALQIMSDDLATLHYRSFGKQKAPLIIRTRGHRLE 602
Query: 650 GVAAQHSQCFGAWYSXCPGLKVLMP 724
G+ S G + G+ VL+P
Sbjct: 603 GIWHAGSP-MGGIINNIRGMHVLVP 626
>UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit;
n=1; Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase E1 component beta subunit -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 309
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/147 (25%), Positives = 61/147 (41%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 481
+ + + +E E ++ LGE+V + GL +KYGDK++ID PI+E
Sbjct: 5 EKFREELFKEFESNKDAIYLGEDVRNAHRGIAI--GLHEKYGDKQIIDMPISESAFTGLA 62
Query: 482 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAA 661
K E+ +D I N A K M + + +++ P G G+A
Sbjct: 63 LGLAISKKKVFVEYNFAGLVYLGLDQIFNQAHKYNEMLNTNLNLDLIYILPTGTRGGLAG 122
Query: 662 QHSQCFGAWYSXCPGLKVLMPLFSKXC 742
HS A S G++ MP + C
Sbjct: 123 HHSDNPYAILSHL-GIQSFMPTNAIDC 148
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 52.0 bits (119), Expect = 2e-05
Identities = 35/140 (25%), Positives = 60/140 (42%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
A+ + +D E+ + KV V GE+V G + T GL +K+G RV DT ++E
Sbjct: 386 AIRKTLDYELATNPKVMVFGEDVGPKGGVHGATLGLNEKFGGDRVFDTSLSEEGIIGRSV 445
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
L P+ E ++ A + + ++ + + P+V R P G A
Sbjct: 446 GLALSGLMPVPEIQFRKYAEPAAEQLSDTGIMR-WRTNNQFAAPMVVRIPGGFARRGDPW 504
Query: 665 HSQCFGAWYSXCPGLKVLMP 724
HS ++ G ++ MP
Sbjct: 505 HSMSDEVEWAHKVGWQLAMP 524
>UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
beta subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, beta
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 359
Score = 51.2 bits (117), Expect = 4e-05
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 521 FMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFGAWYSXC 700
F F++ A++ IN+AAK +++ G P P +FR G G HSQ ++
Sbjct: 85 FQRVEFALLALEQFINNAAKNNFLAGGRRPNPCLFRFVIGRGWGQGPSHSQSLETIFAQI 144
Query: 701 PGLKVLMPLFSK 736
P + VLMP+F +
Sbjct: 145 PNINVLMPVFPR 156
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 48.8 bits (111), Expect = 2e-04
Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 5/149 (3%)
Frame = +2
Query: 302 DALNQAIDEEMERDEKVFVLGEEVAQYD--GAYKVTRGLWKKYGDKRVIDTPITEXXXXX 475
+A+N+ + E + F+ G++VA + G + VT+G+ +++G+ RV PI E
Sbjct: 354 NAINETLKAEFRHNPDTFIWGQDVANREKGGVFNVTKGMQQEFGEARVFSAPIAEDYIVG 413
Query: 476 XXXXXXXXXLK--PICEFMTF-NFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 646
K + E F ++ A++ + + ++ S G I R +G
Sbjct: 414 TANGMSRFDPKIHVVIEGAEFADYFWPAVEQYVECTHE-YWRSNGKFAPNITLRLASGGY 472
Query: 647 SGVAAQHSQCFGAWYSXCPGLKVLMPLFS 733
G HSQ + PG +++ P F+
Sbjct: 473 IGGGLYHSQNIEGALTTLPGARIVCPSFA 501
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 48.4 bits (110), Expect = 3e-04
Identities = 32/125 (25%), Positives = 52/125 (41%)
Frame = +2
Query: 254 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 433
+F +P + +N A+ + M ++ +GE+V + G Y VT+ L +++G
Sbjct: 392 TFGGDMRAMDEPQPMSRLINWALTDLMLEHGEIVCMGEDVGRKGGVYGVTQKLQQRFGPD 451
Query: 434 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 613
R+IDT + E PI E + A D I AA + S G
Sbjct: 452 RMIDTLLDEQSILGLAIGMGHNGFLPIPEIQFLAYLHNAEDQIRGEAATLPFFSNGQFTN 511
Query: 614 PIVFR 628
P+V R
Sbjct: 512 PMVLR 516
>UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta);
n=1; Macaca mulatta|Rep: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta) -
Macaca mulatta
Length = 340
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/87 (26%), Positives = 39/87 (44%)
Frame = +2
Query: 305 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 484
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHII 565
I E ++ A D ++
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQVV 161
>UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase E1
beta subunit; n=5; Deltaproteobacteria|Rep:
Branched-chain keto acid dehydrogenase E1 beta subunit -
Myxococcus xanthus
Length = 352
Score = 40.7 bits (91), Expect = 0.052
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Frame = +2
Query: 356 VLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTF 532
+ GE+V A G + T+GL K ++P+ E +P+ E
Sbjct: 24 IFGEDVGAPLGGVFTCTQGL------KTTWNSPLDERGIIGAAMGIAMAGGRPVAEIQFC 77
Query: 533 NFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFGAWYSXCPGLK 712
++ ID ++ A T + + G +P+V R P G+ + HS F A + G K
Sbjct: 78 DYVYNTID-LLKLAGNTSWSTFGDWNLPMVVRTPVGSGIRGSIYHSHSFDATMTHIAGWK 136
Query: 713 VLMP 724
V+MP
Sbjct: 137 VVMP 140
>UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Magnetospirillum magnetotacticum MS-1
Length = 188
Score = 38.3 bits (85), Expect = 0.28
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Frame = +2
Query: 269 KALAS-KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGD 430
K AS K T+R+AL A+D EM D V + G Y GA + GLW+ D
Sbjct: 116 KVYASYKRQTIREALRDAMDREMRADPDVLLNGRGTGPYHGANRAA-GLWRNGAD 169
>UniRef50_A7P4X0 Cluster: Chromosome chr4 scaffold_6, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr4 scaffold_6, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 111
Score = 37.5 bits (83), Expect = 0.48
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +3
Query: 681 VPGTAXVQALKF*CLYSAXDAKGLLKAXIRDPXPVVMLEXEIXXG 815
+ G LK YS+ DA GLLK +RD PVV LE E+ G
Sbjct: 53 ITGYGSYSGLKALSPYSSEDAHGLLKVVMRDLDPVVFLENELLYG 97
>UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 376
Score = 37.1 bits (82), Expect = 0.64
Identities = 24/74 (32%), Positives = 34/74 (45%)
Frame = +2
Query: 503 LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFG 682
+KP+ E ++ A D I+N AAK Y T G A A HSQ
Sbjct: 135 MKPVAEIQFADYVFPAFDQIVNEAAKFRYREGAT----------GGNAGHGALYHSQSPE 184
Query: 683 AWYSXCPGLKVLMP 724
A ++ PGL+V++P
Sbjct: 185 ALFAHIPGLQVVIP 198
>UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GabT1 - Bacillus
amyloliquefaciens FZB42
Length = 425
Score = 35.9 bits (79), Expect = 1.5
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +2
Query: 275 LASKPVTVRDALNQAIDEE-MERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 448
+ +K +T D+L ++D+ MER E +++ +E +Y T L YG+K VIDT
Sbjct: 4 VGTKEITNPDSLYYSVDDVVMERGEGIYLYDQEGNEYIDCASATFNLNLGYGNKEVIDT 62
>UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas
palustris HaA2|Rep: Tyrosinase - Rhodopseudomonas
palustris (strain HaA2)
Length = 416
Score = 34.3 bits (75), Expect = 4.5
Identities = 19/51 (37%), Positives = 27/51 (52%)
Frame = +2
Query: 260 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGL 412
A+ LASKPV VR N + ERD+ + LG A+ G Y++ R +
Sbjct: 102 ASGAPLASKPVMVRIRKNAVTLSQEERDDFLAALGTLNARGQGPYRIVRDM 152
>UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2;
Parabacteroides|Rep: Putative uncharacterized protein -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 334
Score = 34.3 bits (75), Expect = 4.5
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 245 SRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKK 421
++ +F +A + VR + + + EK F L E Y G Y+ V RGLW+
Sbjct: 221 AQEAFTEDYLVAMRDSVVRRNVPGSFPNSYMKTEKRFELSYEPITYRGEYRGVLRGLWRM 280
Query: 422 YGDK 433
GDK
Sbjct: 281 EGDK 284
>UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion
sequence element; n=7; Mycoplasma penetrans|Rep:
Transposase for IS1202-like insertion sequence element -
Mycoplasma penetrans
Length = 562
Score = 33.9 bits (74), Expect = 5.9
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +2
Query: 233 LTRLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKV 352
L ++ R+S ATSKA+ K R AL + D ER+EK+
Sbjct: 512 LEKIKRKSIATSKAIYQKNENTRIALERWSDSLKEREEKI 551
>UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11680,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 462
Score = 33.5 bits (73), Expect = 7.8
Identities = 13/26 (50%), Positives = 14/26 (53%)
Frame = -2
Query: 684 APKHWECCAATPEAAPLGPRNTIGTG 607
AP HWE PLGPR +GTG
Sbjct: 287 APVHWEFSLEPAAGGPLGPRGPVGTG 312
>UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifica
SIR-1|Rep: Transketolase - Plesiocystis pacifica SIR-1
Length = 336
Score = 33.5 bits (73), Expect = 7.8
Identities = 28/137 (20%), Positives = 61/137 (44%), Gaps = 1/137 (0%)
Frame = +2
Query: 308 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK-RVIDTPITEXXXXXXXX 484
L + + E + DE+ +LGE+V G ++R + + + R++ P+T
Sbjct: 7 LARLLVELLREDERRCLLGEDVGN-GGMLGLSRAVAEDEQLRARLMPAPLTVNAGVAHAG 65
Query: 485 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQ 664
L+PI + + ++A+ + + + S +P++F PNG G+ +
Sbjct: 66 GLALAGLRPIVVLPSASALLEALP-ALRELGRLPWRSGEQHDLPVLFVVPNGPGFGIGGE 124
Query: 665 HSQCFGAWYSXCPGLKV 715
++ A + PGL++
Sbjct: 125 AAESVEATLARVPGLEL 141
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 823,385,986
Number of Sequences: 1657284
Number of extensions: 15936769
Number of successful extensions: 39569
Number of sequences better than 10.0: 108
Number of HSP's better than 10.0 without gapping: 38014
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39510
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 85260991088
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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