Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP11_F_A11
(915 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 118 4e-26
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 118 4e-26
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 118 4e-26
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 118 4e-26
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 118 4e-26
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 118 4e-26
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 118 4e-26
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 117 7e-26
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 117 7e-26
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 116 9e-26
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 116 1e-25
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 116 1e-25
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 116 1e-25
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 116 1e-25
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 116 1e-25
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 116 1e-25
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 116 1e-25
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 116 1e-25
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 116 1e-25
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 116 1e-25
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 116 1e-25
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 116 1e-25
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 115 2e-25
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 115 3e-25
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 115 3e-25
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 114 5e-25
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 114 5e-25
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 114 5e-25
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 114 5e-25
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 114 5e-25
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 114 5e-25
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 114 5e-25
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 113 6e-25
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 113 6e-25
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 113 6e-25
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 113 6e-25
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 113 6e-25
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 113 6e-25
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 113 6e-25
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 113 6e-25
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 113 6e-25
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 113 6e-25
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 113 6e-25
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 113 6e-25
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 113 1e-24
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 113 1e-24
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 112 1e-24
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 111 3e-24
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 111 3e-24
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 111 3e-24
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 111 3e-24
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 111 3e-24
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 111 3e-24
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 111 3e-24
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 111 3e-24
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 111 3e-24
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 111 3e-24
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 108 2e-23
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 108 2e-23
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 108 2e-23
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 108 2e-23
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 105 2e-22
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 104 4e-22
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 102 2e-21
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 102 2e-21
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 102 2e-21
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 102 2e-21
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 102 2e-21
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 99 1e-20
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 99 1e-20
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 99 1e-20
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 99 1e-20
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 99 1e-20
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 99 1e-20
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 99 1e-20
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 99 1e-20
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 99 1e-20
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 99 2e-20
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 97 6e-20
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 97 6e-20
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 97 6e-20
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 97 6e-20
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 97 1e-19
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 92 2e-18
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 92 2e-18
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 92 2e-18
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 92 2e-18
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 92 2e-18
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 92 2e-18
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 70 2e-13
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 37 0.089
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 36 0.16
AK124556-1|BAC85883.1| 127|Homo sapiens protein ( Homo sapiens ... 33 1.1
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 33 1.1
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 129
Query: 721 SIP 729
P
Sbjct: 130 LSP 132
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 195
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 118 bits (283), Expect = 4e-26
Identities = 58/123 (47%), Positives = 82/123 (66%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 117 bits (281), Expect = 7e-26
Identities = 58/123 (47%), Positives = 81/123 (65%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 39.9 bits (89), Expect = 0.013
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVEC 193
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 117 bits (281), Expect = 7e-26
Identities = 55/120 (45%), Positives = 76/120 (63%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P+ K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 116 bits (280), Expect = 9e-26
Identities = 58/123 (47%), Positives = 81/123 (65%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V R+++F KLWSTFHR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 39.9 bits (89), Expect = 0.013
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVEC 193
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 44.0 bits (99), Expect = 8e-04
Identities = 23/43 (53%), Positives = 28/43 (65%), Gaps = 2/43 (4%)
Frame = +2
Query: 788 MEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 145 MEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 116 bits (279), Expect = 1e-25
Identities = 55/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 139 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 184
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 115 bits (277), Expect = 2e-25
Identities = 54/118 (45%), Positives = 74/118 (62%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+ +
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 556 TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P K G P
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Score = 47.6 bits (108), Expect = 6e-05
Identities = 24/46 (52%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 57/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ GY ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 35.5 bits (78), Expect = 0.27
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I + K +P NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVEC 193
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 115 bits (276), Expect = 3e-25
Identities = 54/120 (45%), Positives = 75/120 (62%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 549
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 550 DGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIP 729
+ V+R+ELFI+ KLW T+H G Q +L+DL L++ DL+LIH P + G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/46 (52%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL IG+SNFN + I +K K KPAVNQ+EC
Sbjct: 142 WAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIEC 187
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 193
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 721 SIPK 732
+PK
Sbjct: 126 PLPK 129
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 191
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVEC 193
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 193
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 193
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 193
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 114 bits (274), Expect = 5e-25
Identities = 55/124 (44%), Positives = 82/124 (66%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 721 SIPK 732
+PK
Sbjct: 128 PLPK 131
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 193
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 35.5 bits (78), Expect = 0.27
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I + K +P NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVEC 193
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 57/123 (46%), Positives = 81/123 (65%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWST HR L++SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 721 SIPK 732
IPK
Sbjct: 141 VIPK 144
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 161 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 206
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 113 bits (273), Expect = 6e-25
Identities = 56/124 (45%), Positives = 81/124 (65%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLWS HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 38.7 bits (86), Expect = 0.029
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVEC 193
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 113 bits (271), Expect = 1e-24
Identities = 58/134 (43%), Positives = 85/134 (63%), Gaps = 4/134 (2%)
Frame = +1
Query: 352 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 522
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 523 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMS 702
G+AI KI DGTV+R+E+F KLW+TF R L+ SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 703 LKE-GNSSIPKISS 741
+K+ G +PK +S
Sbjct: 125 MKQPGKELLPKDAS 138
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 113 bits (271), Expect = 1e-24
Identities = 58/134 (43%), Positives = 85/134 (63%), Gaps = 4/134 (2%)
Frame = +1
Query: 352 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 522
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 523 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMS 702
G+AI KI DGTV+R+E+F KLW+TF R L+ SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 703 LKE-GNSSIPKISS 741
+K+ G +PK +S
Sbjct: 125 MKQPGKELLPKDAS 138
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 112 bits (270), Expect = 1e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 721 SIPK 732
IPK
Sbjct: 125 VIPK 128
Score = 35.5 bits (78), Expect = 0.27
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E L +IGVSNFN + + I K +VKP NQVEC
Sbjct: 145 WEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVEC 190
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 111 bits (268), Expect = 3e-24
Identities = 55/124 (44%), Positives = 80/124 (64%), Gaps = 3/124 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 721 SIPK 732
IPK
Sbjct: 128 VIPK 131
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 148 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 108 bits (260), Expect = 2e-23
Identities = 53/123 (43%), Positives = 77/123 (62%), Gaps = 3/123 (2%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 540
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G A+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 541 KIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
KI DG+V+R+++F KLW HR L+ SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 721 SIP 729
P
Sbjct: 128 LSP 130
Score = 40.7 bits (91), Expect = 0.007
Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
T W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 146 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 108 bits (260), Expect = 2e-23
Identities = 54/122 (44%), Positives = 78/122 (63%), Gaps = 3/122 (2%)
Frame = +1
Query: 352 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 522
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 523 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMS 702
G+AI KI DGTV+R+E+F KLW+TF R L+ SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 703 LK 708
+K
Sbjct: 125 MK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 108 bits (260), Expect = 2e-23
Identities = 54/122 (44%), Positives = 78/122 (63%), Gaps = 3/122 (2%)
Frame = +1
Query: 352 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 522
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 523 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMS 702
G+AI KI DGTV+R+E+F KLW+TF R L+ SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 703 LK 708
+K
Sbjct: 125 MK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 108 bits (260), Expect = 2e-23
Identities = 54/122 (44%), Positives = 78/122 (63%), Gaps = 3/122 (2%)
Frame = +1
Query: 352 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 522
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 523 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMS 702
G+AI KI DGTV+R+E+F KLW+TF R L+ SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 703 LK 708
+K
Sbjct: 125 MK 126
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 105 bits (252), Expect = 2e-22
Identities = 51/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +1
Query: 394 MPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVR 564
MPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++KI DG+V+
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 565 RDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
R+++F KLW TF + L+ SL L L++ DL+L+H PM+LK G + +PK
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPK 116
Score = 38.3 bits (85), Expect = 0.038
Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL +IGVSNFN + I K K KP NQVEC
Sbjct: 133 WEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVEC 178
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 104 bits (250), Expect = 4e-22
Identities = 54/127 (42%), Positives = 79/127 (62%), Gaps = 3/127 (2%)
Frame = +1
Query: 349 SVKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKL 519
S + ++KL DG FMP++ GT++ + E V+ AID+GYR ID+AY + NE+
Sbjct: 2 SFNRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 520 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPM 699
IG+AI+ KI +GTV+R ++F K+W TF R GL+ SL L L + DL+L H P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 700 SLKEGNS 720
L+ G S
Sbjct: 122 PLQPGRS 128
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 102 bits (245), Expect = 2e-21
Identities = 49/113 (43%), Positives = 67/113 (59%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI+ KLW TF + +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 102 bits (245), Expect = 2e-21
Identities = 49/113 (43%), Positives = 67/113 (59%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI+ KLW TF + +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 102 bits (245), Expect = 2e-21
Identities = 49/113 (43%), Positives = 67/113 (59%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI+ KLW TF + +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 102 bits (245), Expect = 2e-21
Identities = 49/113 (43%), Positives = 67/113 (59%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI+ KLW TF + +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 102 bits (245), Expect = 2e-21
Identities = 49/113 (43%), Positives = 67/113 (59%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI+ KLW TF + +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 99 bits (238), Expect = 1e-20
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = +1
Query: 376 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 555
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 556 -TVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
V R+ELF+ KLW+T H L+ +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 733 -ISSVIQYSEFDYMD 774
I Y Y +
Sbjct: 128 NADGTICYDSTHYKE 142
Score = 44.0 bits (99), Expect = 8e-04
Identities = 22/44 (50%), Positives = 27/44 (61%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKGKVKPAVNQVEC 910
W +E LV KGL +G+SNFN I I + V+PAV QVEC
Sbjct: 144 WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 99.1 bits (236), Expect = 2e-20
Identities = 48/113 (42%), Positives = 65/113 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
LFI KLW TF + +L D L + D++LIH P K G+ PK
Sbjct: 73 LFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPK 125
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME+LV +GL +GVSNF+ I K+ K K KP NQVEC
Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 97.5 bits (232), Expect = 6e-20
Identities = 53/125 (42%), Positives = 75/125 (60%), Gaps = 4/125 (3%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 537
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 538 NKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGN 717
KI +G VRR+++F GKLW+T H L+ +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 718 SSIPK 732
P+
Sbjct: 130 EIYPR 134
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL ++GVSNFN + I K K KP NQVEC
Sbjct: 151 WEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 196
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 97.5 bits (232), Expect = 6e-20
Identities = 53/125 (42%), Positives = 75/125 (60%), Gaps = 4/125 (3%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 537
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 538 NKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGN 717
KI +G VRR+++F GKLW+T H L+ +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 718 SSIPK 732
P+
Sbjct: 130 EIYPR 134
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL ++GVSNFN + I K K KP NQVEC
Sbjct: 151 WEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 196
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 97.5 bits (232), Expect = 6e-20
Identities = 53/125 (42%), Positives = 75/125 (60%), Gaps = 4/125 (3%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 537
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 538 NKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGN 717
KI +G VRR+++F GKLW+T H L+ +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 718 SSIPK 732
P+
Sbjct: 130 EIYPR 134
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL ++GVSNFN + I K K KP NQVEC
Sbjct: 151 WEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 196
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 97.5 bits (232), Expect = 6e-20
Identities = 53/125 (42%), Positives = 75/125 (60%), Gaps = 4/125 (3%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 537
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 538 NKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGN 717
KI +G VRR+++F GKLW+T H L+ +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 718 SSIPK 732
P+
Sbjct: 130 EIYPR 134
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL ++GVSNFN + I K K KP NQVEC
Sbjct: 151 WEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 196
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 96.7 bits (230), Expect = 1e-19
Identities = 48/114 (42%), Positives = 72/114 (63%), Gaps = 3/114 (2%)
Frame = +1
Query: 400 VIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRD 570
V+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++KI DG+V+R+
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 571 ELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNSSIPK 732
++F KLW HR L+ SL +L L++ DL+LIH P+S+K G IPK
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK 114
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 131 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 176
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W MEDLV GL NIGVSNFN + ++ K + KP NQ+EC
Sbjct: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIEC 197
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W MEDLV GL NIGVSNFN + ++ K + KP NQ+EC
Sbjct: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIEC 197
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 46.8 bits (106), Expect = 1e-04
Identities = 23/46 (50%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W MEDLV GL NIGVSNFN + ++ K + KP NQ+EC
Sbjct: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIEC 197
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 41.1 bits (92), Expect = 0.005
Identities = 21/44 (47%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQV 904
W MEDLV GL NIGVSNFN + ++ K + KP NQ+
Sbjct: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/105 (43%), Positives = 60/105 (57%)
Frame = +1
Query: 394 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 573
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 574 LFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLK 708
LFI KLW T H+ + SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 41.1 bits (92), Expect = 0.005
Identities = 21/44 (47%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQV 904
W MEDLV GL NIGVSNFN + ++ K + KP NQ+
Sbjct: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 69.7 bits (163), Expect(2) = 2e-13
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +1
Query: 520 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPM 699
+G AI++KI DG+V+R+++F KLW HR L+ SL +L L++ DL+LIH P+
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 86
Query: 700 SLKEGNSSIPK 732
S+K G IPK
Sbjct: 87 SVKPGEEVIPK 97
Score = 37.5 bits (83), Expect = 0.067
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W +E GL +IGVSNFN + I K K KP NQVEC
Sbjct: 114 WEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 159
Score = 26.2 bits (55), Expect(2) = 2e-13
Identities = 10/16 (62%), Positives = 12/16 (75%)
Frame = +1
Query: 370 LKLRDGTFMPVIALGT 417
+KL DG FMPV+ GT
Sbjct: 6 VKLNDGHFMPVLGFGT 21
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 37.1 bits (82), Expect = 0.089
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +1
Query: 592 LWSTFHRTGSGGDGLQDSLADLGLEFFDLFLIHNPMSLKEGNS 720
+W TF R GL+ SL L L + DL+L H P+ L+ G S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = +2
Query: 779 WFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQVEC 910
W ME GL ++GVSNFN + I K K KP NQVEC
Sbjct: 29 WEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 74
>AK124556-1|BAC85883.1| 127|Homo sapiens protein ( Homo sapiens
cDNA FLJ42565 fis, clone BRACE3007472. ).
Length = 127
Score = 33.5 bits (73), Expect = 1.1
Identities = 22/52 (42%), Positives = 24/52 (46%)
Frame = -2
Query: 659 PRSASESCRPSPPDPVRWNVLHNLPIMKSSSRLTVPSSILFLIAFPMSFSLP 504
PRS S R PP P RW L LP + S TVP IL L A +P
Sbjct: 4 PRSFRGSPRVPPPGPPRWTSLRPLPSLDHISAPTVP-DILALHATSRPMIMP 54
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 33.5 bits (73), Expect = 1.1
Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = +2
Query: 773 TPWFGMEDLVXKGLXXNIGVSNFNLTXILKIWTKG--KVKPAVNQ 901
T W ME GL +IGVSNFN + I K K KP NQ
Sbjct: 23 TTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,970,087
Number of Sequences: 237096
Number of extensions: 2796038
Number of successful extensions: 11617
Number of sequences better than 10.0: 94
Number of HSP's better than 10.0 without gapping: 10778
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11489
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11881370308
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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