Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP08_F_P04
(895 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleot... 120 7e-27
S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase ... 120 7e-27
BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductas... 120 7e-27
BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductas... 120 7e-27
AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductas... 120 7e-27
AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein. 120 7e-27
DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens ... 114 5e-25
AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible ribonucle... 114 5e-25
AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductas... 114 5e-25
BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleoti... 103 9e-22
AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible ribonucle... 103 9e-22
BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleoti... 34 0.61
D10704-1|BAA01547.1| 456|Homo sapiens choline kinase protein. 32 3.2
>X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleotide
reductase protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase R2
subunit protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductase
M2 subunit protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein.
Length = 389
Score = 120 bits (289), Expect = 7e-27
Identities = 63/126 (50%), Positives = 80/126 (63%), Gaps = 7/126 (5%)
Frame = +2
Query: 134 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 292
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 293 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 472
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 473 KHVLGF 490
HVL F
Sbjct: 128 SHVLAF 133
Score = 105 bits (252), Expect = 2e-22
Identities = 53/91 (58%), Positives = 63/91 (69%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVKESFSQA 807
LIDTYI+DPKER+FLFNA+ET+PCVKKKADWAL+WI + AT+GER+VAFAAV+ F
Sbjct: 179 LIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSG 238
Query: 808 VLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
K G G FSN L + GLH
Sbjct: 239 SFASIFWLKKRGLMPGLTFSNELISRDEGLH 269
Score = 101 bits (243), Expect = 3e-21
Identities = 59/115 (51%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAY-RYLHQRSEGERFSV*C 680
DGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSL Y+ E E F
Sbjct: 138 DGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKERE-FLFNA 196
Query: 681 G*DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ ++ + + + IFFSGSFASIFWLK L
Sbjct: 197 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 251
>DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ11103 fis, clone PLACE1005656, highly similar to
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN (EC
1.17.4.1). ).
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 114 bits (274), Expect = 5e-25
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 251 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 430
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 431 SDWETLKDSERHFIKHVLGF 490
W LK E++FI H+L F
Sbjct: 76 PHWNKLKADEKYFISHILAF 95
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 141 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 200
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 201 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 231
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 100 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 159
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 160 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 213
>BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleotide
reductase M2 polypeptide protein.
Length = 285
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 75 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 134
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 135 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 165
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 34 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 93
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 94 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 147
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/29 (62%), Positives = 21/29 (72%)
Frame = +2
Query: 404 EEVDLSKDLSDWETLKDSERHFIKHVLGF 490
EEVDLSKDL W LK E++FI H+L F
Sbjct: 1 EEVDLSKDLPHWNKLKADEKYFISHILAF 29
>AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 long form
protein.
Length = 299
Score = 103 bits (247), Expect = 9e-22
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 2/91 (2%)
Frame = +1
Query: 628 LIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASRTATFGERIVAFAAVK-ESFSQ 804
LIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA R +TFGER+VAFAAV+ FS
Sbjct: 89 LIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSG 148
Query: 805 AVLLPSSGSKXGPYAGTXFSNXLF-QG*GLH 894
+ K G G FSN L + GLH
Sbjct: 149 SFAAIFWLKKRGLMPGLTFSNELISRDEGLH 179
Score = 94.3 bits (224), Expect = 5e-19
Identities = 53/114 (46%), Positives = 65/114 (57%)
Frame = +3
Query: 504 DGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLAYRYLHQRSEGERFSV*CG 683
DGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSL + + F
Sbjct: 48 DGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAI 107
Query: 684 *DSSLCKEESRLGSTVDCKQDCNIW*KDCCLCSCKRIFFSGSFASIFWLKXGAL 845
K+++ + + + + +FFSGSFA+IFWLK L
Sbjct: 108 ETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGL 161
Score = 44.0 bits (99), Expect = 7e-04
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 374 KKAEASFWTVEEVDLSKDLSDWETLKDSERHFIKHVLGF 490
++ EA+ +EVDLSKDL W LK E++FI H+L F
Sbjct: 5 ERPEAAGLDQDEVDLSKDLPHWNKLKADEKYFISHILAF 43
>BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleotide
reductase protein r2 class I protein.
Length = 172
Score = 34.3 bits (75), Expect = 0.61
Identities = 15/18 (83%), Positives = 15/18 (83%)
Frame = +3
Query: 792 IFFSGSFASIFWLKXGAL 845
IFFSGSFASIFWLK L
Sbjct: 17 IFFSGSFASIFWLKKRGL 34
Score = 31.5 bits (68), Expect = 4.3
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Frame = +1
Query: 748 ATFGERIVAFAAVKESFSQAVLLPSSG-SKXGPYAGTXFSNXLF-QG*GLH 894
AT+GER+VAFAAV+ F K G G FSN L + GLH
Sbjct: 2 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLH 52
>D10704-1|BAA01547.1| 456|Homo sapiens choline kinase protein.
Length = 456
Score = 31.9 bits (69), Expect = 3.2
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Frame = -3
Query: 824 EDGSKTA*EKDSFTAAKATILSPNVAVLLAIHCRAQSAF-FFTQGRVSTALNRKSLSFGS 648
++GS+ A +++ F A+A +L + +LA + F QGR+ + + L
Sbjct: 158 KEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEE 217
Query: 647 LM*VSISQGIHFRMNIFHG 591
L IS I +M FHG
Sbjct: 218 LSLPDISAEIAEKMATFHG 236
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,505,922
Number of Sequences: 237096
Number of extensions: 2725370
Number of successful extensions: 5821
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5346
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5805
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11492727354
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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