Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP08_F_M22
(882 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 111 6e-41
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 111 6e-41
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 111 6e-41
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 162 1e-39
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 160 5e-39
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 160 5e-39
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 160 5e-39
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 160 5e-39
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 160 5e-39
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 160 5e-39
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 160 5e-39
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 160 5e-39
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 160 5e-39
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 160 5e-39
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 160 5e-39
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 160 5e-39
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 160 5e-39
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 155 2e-37
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 155 2e-37
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 155 2e-37
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 155 2e-37
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 155 2e-37
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 155 2e-37
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 155 2e-37
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 155 2e-37
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 155 3e-37
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 149 1e-35
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 149 2e-35
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 149 2e-35
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 149 2e-35
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 149 2e-35
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 149 2e-35
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 149 2e-35
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 149 2e-35
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 148 2e-35
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 148 2e-35
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 148 3e-35
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 148 3e-35
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 148 3e-35
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 148 3e-35
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 148 3e-35
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 148 3e-35
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 148 3e-35
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 148 3e-35
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 148 3e-35
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 148 3e-35
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 148 3e-35
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 111 4e-35
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 111 4e-35
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 147 4e-35
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 147 4e-35
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 147 4e-35
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 147 4e-35
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 147 4e-35
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 146 7e-35
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 146 7e-35
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 146 7e-35
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 146 7e-35
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 146 7e-35
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 146 7e-35
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 146 7e-35
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 146 7e-35
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 146 7e-35
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 146 7e-35
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 146 9e-35
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 145 2e-34
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 145 2e-34
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 144 3e-34
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 141 3e-33
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 141 3e-33
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 141 3e-33
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 141 3e-33
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 141 3e-33
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 141 3e-33
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 141 3e-33
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 140 5e-33
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 134 5e-31
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 134 5e-31
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 134 5e-31
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 134 5e-31
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 124 3e-28
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 111 4e-24
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 107 5e-23
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 107 5e-23
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 105 3e-22
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 99 2e-20
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 98 3e-20
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 98 3e-20
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 98 3e-20
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 45 4e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.012
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 38 0.048
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 38 0.048
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 38 0.048
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 38 0.048
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 38 0.048
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 38 0.048
AF007190-1|AAC02268.1| 513|Homo sapiens intestinal mucin protein. 31 4.2
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 111 bits (266), Expect(2) = 6e-41
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 77.4 bits (182), Expect(2) = 6e-41
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +2
Query: 533 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQ 706
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 707 KEMVEFCQSEGVVVMGYXLXG 769
K ++ FCQS V V Y G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 111 bits (266), Expect(2) = 6e-41
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 77.4 bits (182), Expect(2) = 6e-41
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +2
Query: 533 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQ 706
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 707 KEMVEFCQSEGVVVMGYXLXG 769
K ++ FCQS V V Y G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 111 bits (266), Expect(2) = 6e-41
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 77.4 bits (182), Expect(2) = 6e-41
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +2
Query: 533 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQ 706
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 707 KEMVEFCQSEGVVVMGYXLXG 769
K ++ FCQS V V Y G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 85/196 (43%), Positives = 118/196 (60%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWPIG + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 160 bits (389), Expect = 5e-39
Identities = 84/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 16 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 75
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 76 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 135
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 136 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 195
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 196 YCQSKGIVVTAYSPLG 211
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 155 bits (376), Expect = 2e-37
Identities = 78/195 (40%), Positives = 114/195 (58%), Gaps = 12/195 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYS--HSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD + +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEVHLQNVQKEMVEF 724
+ ETW+ LE G+V+ +GLSNFN +Q++ +L +++P Q+E H Q E++
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 725 CQSEGVVVMGYXLXG 769
CQ+ G+ V Y G
Sbjct: 200 CQARGLEVTAYSPLG 214
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 155 bits (375), Expect = 3e-37
Identities = 83/196 (42%), Positives = 116/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 547
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++T +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+CQS+G+VV Y G
Sbjct: 199 YCQSKGIVVTAYSPLG 214
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 149 bits (361), Expect = 1e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 21 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 80
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 81 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 140
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 141 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 200
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 201 RSKLLDFCKSKDIVLVAYSALG 222
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 149 bits (360), Expect = 2e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 148 bits (359), Expect = 2e-35
Identities = 75/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L E +K P Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 148 bits (359), Expect = 2e-35
Identities = 76/202 (37%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ GY H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L E +K P Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 2 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 61
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 62 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 121
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 122 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 181
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 182 QRKLLDFCKSKDIVLVAYSALG 203
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 148 bits (358), Expect = 3e-35
Identities = 76/202 (37%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 111 bits (266), Expect(2) = 4e-35
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 58.0 bits (134), Expect(2) = 4e-35
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 533 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQ 706
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QI + Q +Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ-IQ 202
Query: 707 KEMV 718
+ ++
Sbjct: 203 RNVI 206
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 111 bits (266), Expect(2) = 4e-35
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 58.0 bits (134), Expect(2) = 4e-35
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 533 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQ 706
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QI + Q +Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ-IQ 202
Query: 707 KEMV 718
+ ++
Sbjct: 203 RNVI 206
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 147 bits (357), Expect = 4e-35
Identities = 77/196 (39%), Positives = 115/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 147 bits (357), Expect = 4e-35
Identities = 77/196 (39%), Positives = 115/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 147 bits (357), Expect = 4e-35
Identities = 77/196 (39%), Positives = 115/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 147 bits (357), Expect = 4e-35
Identities = 77/196 (39%), Positives = 115/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 147 bits (357), Expect = 4e-35
Identities = 77/196 (39%), Positives = 115/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 32 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 91
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 92 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 151
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 152 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 211
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 212 QRKLLDFCKSKDIVLVAYSALG 233
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 146 bits (355), Expect = 7e-35
Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + V AI+ G+ H D+A VY E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 79 IFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN + LE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALG 220
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 146 bits (354), Expect = 9e-35
Identities = 78/202 (38%), Positives = 120/202 (59%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G V+RED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVERED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 145 bits (352), Expect = 2e-34
Identities = 78/202 (38%), Positives = 119/202 (58%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G V RED
Sbjct: 19 LGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVMRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 145 bits (351), Expect = 2e-34
Identities = 78/202 (38%), Positives = 116/202 (57%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G AV+ K+ +G VKRED
Sbjct: 19 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD------ 538
IF T+KLW HR V A+ SLKK LDY+DLYL+H P+ L + S +D
Sbjct: 79 IFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVI 138
Query: 539 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E H
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
+ ++++FC+S+ +V++ Y G
Sbjct: 199 RSKLLDFCKSKDIVLVAYSALG 220
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 144 bits (350), Expect = 3e-34
Identities = 76/196 (38%), Positives = 114/196 (58%), Gaps = 13/196 (6%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 400
G KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIASK 78
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSD---------VDF 547
LW T R V +A +LK L Y+D+YL+HWP G + D D F
Sbjct: 79 LWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATF 138
Query: 548 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNVQKEMVE 721
++ W +E+ G+VK +G+SNF+ Q+E++L K G KP Q+E H Q+++++
Sbjct: 139 LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQ 198
Query: 722 FCQSEGVVVMGYXLXG 769
+C S+G+ V Y G
Sbjct: 199 YCHSKGITVTAYSPLG 214
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 142 bits (343), Expect = 2e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 4 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 63
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 64 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 123
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 124 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 183
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 184 QSKLLDFCKSKDIVLVAHSALG 205
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 17 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 76
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 77 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 136
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 137 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 196
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 197 QSKLLDFCKSKDIVLVAHSALG 218
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 141 bits (342), Expect = 3e-33
Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + +V AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 19 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 78
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L N
Sbjct: 79 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 138
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + G+ K IG+SNFN +QLE +L K G KP Q+E H
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 198
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q ++++FC+S+ +V++ + G
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALG 220
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 140 bits (340), Expect = 5e-33
Identities = 73/202 (36%), Positives = 112/202 (55%), Gaps = 13/202 (6%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + + + AI+ G+RH D+A +Y E+++G A++ K+ +G VKRED
Sbjct: 16 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 75
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS 529
IF T+KLW HR A+ SLK L LDY+DLYL+H+P+ + N
Sbjct: 76 IFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 135
Query: 530 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQIEVHLQNV 703
VD TW +E + + K IG+SNFN+ LE +L K G +KP Q+E H
Sbjct: 136 FDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFN 195
Query: 704 QKEMVEFCQSEGVVVMGYXLXG 769
Q+++++FC+S+ +V++ Y G
Sbjct: 196 QRKLLDFCKSKDIVLVAYSALG 217
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 134 bits (323), Expect = 5e-31
Identities = 67/180 (37%), Positives = 102/180 (56%), Gaps = 13/180 (7%)
Frame = +2
Query: 269 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 448
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 449 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 595
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 596 KGIGLSNFNKQQLERVLKEGTI--KPDAXQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ Y G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 134 bits (323), Expect = 5e-31
Identities = 67/180 (37%), Positives = 102/180 (56%), Gaps = 13/180 (7%)
Frame = +2
Query: 269 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 448
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 449 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 595
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 596 KGIGLSNFNKQQLERVLKEGTI--KPDAXQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ Y G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 134 bits (323), Expect = 5e-31
Identities = 67/180 (37%), Positives = 102/180 (56%), Gaps = 13/180 (7%)
Frame = +2
Query: 269 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 448
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 449 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 595
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 596 KGIGLSNFNKQQLERVLKEGTI--KPDAXQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ Y G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 134 bits (323), Expect = 5e-31
Identities = 67/180 (37%), Positives = 102/180 (56%), Gaps = 13/180 (7%)
Frame = +2
Query: 269 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 448
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 449 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 595
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 596 KGIGLSNFNKQQLERVLKEGTI--KPDAXQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ Y G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 124 bits (300), Expect = 3e-28
Identities = 65/161 (40%), Positives = 95/161 (59%), Gaps = 13/161 (8%)
Frame = +2
Query: 326 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 505
E+G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 506 IGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-K 649
+ + N VD TW +E + G+ K IG+SNFN++QLE +L K
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 650 EG-TIKPDAXQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
G KP Q+E H Q+++++FC+S+ +V++ Y G
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 186
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 111 bits (266), Expect(2) = 4e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Frame = +2
Query: 230 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 409
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 410 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 511
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 21.0 bits (42), Expect(2) = 4e-24
Identities = 6/9 (66%), Positives = 8/9 (88%)
Frame = +2
Query: 533 SDVDFMETW 559
SD DF++TW
Sbjct: 144 SDTDFLDTW 152
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 107 bits (257), Expect = 5e-23
Identities = 68/192 (35%), Positives = 105/192 (54%), Gaps = 3/192 (1%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+
Sbjct: 22 LGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREE 81
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWR 562
IF T KLW T R V A+ SLKKLG DY+DL+++H P + + +
Sbjct: 82 IFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM----KQPGKELLP--- 134
Query: 563 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQ-IEVHLQNVQKEMVEFCQS 733
+DA I++ + L + +LE +L K G KP Q +E H Q +++EFC+S
Sbjct: 135 --KDASGEIILETVELC--DTWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKS 190
Query: 734 EGVVVMGYXLXG 769
+ +V++ Y G
Sbjct: 191 KDIVLVAYSALG 202
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 107 bits (257), Expect = 5e-23
Identities = 68/192 (35%), Positives = 105/192 (54%), Gaps = 3/192 (1%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+
Sbjct: 22 LGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREE 81
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWR 562
IF T KLW T R V A+ SLKKLG DY+DL+++H P + + +
Sbjct: 82 IFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM----KQPGKELLP--- 134
Query: 563 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAXQ-IEVHLQNVQKEMVEFCQS 733
+DA I++ + L + +LE +L K G KP Q +E H Q +++EFC+S
Sbjct: 135 --KDASGEIILETVELC--DTWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKS 190
Query: 734 EGVVVMGYXLXG 769
+ +V++ Y G
Sbjct: 191 KDIVLVAYSALG 202
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 105 bits (251), Expect = 3e-22
Identities = 55/128 (42%), Positives = 75/128 (58%), Gaps = 12/128 (9%)
Frame = +2
Query: 221 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VVKREDIFITT 397
G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V RE++F+T+
Sbjct: 20 GTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTS 79
Query: 398 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD--YSHSDVD 544
KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD +
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 545 FMETWRGL 568
+ ETW+ L
Sbjct: 140 YKETWKAL 147
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 99.1 bits (236), Expect = 2e-20
Identities = 48/104 (46%), Positives = 65/104 (62%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + K + + V AIDVGYRH D+A + E+ IG+A++ K+ G VKR+D
Sbjct: 20 LGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRKKIANGTVKRKD 79
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 514
IF TTK+W T R V + + SLKKL L Y+DLYL H+P+ L
Sbjct: 80 IFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 98.3 bits (234), Expect = 3e-20
Identities = 46/104 (44%), Positives = 65/104 (62%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+
Sbjct: 22 LGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREE 81
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 514
IF T KLW T R V A+ SLKKLG DY+DL+++H P +
Sbjct: 82 IFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 98.3 bits (234), Expect = 3e-20
Identities = 46/104 (44%), Positives = 65/104 (62%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+
Sbjct: 22 LGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREE 81
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 514
IF T KLW T R V A+ SLKKLG DY+DL+++H P +
Sbjct: 82 IFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 98.3 bits (234), Expect = 3e-20
Identities = 46/104 (44%), Positives = 65/104 (62%)
Frame = +2
Query: 203 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 382
LGF + Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+
Sbjct: 22 LGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREE 81
Query: 383 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 514
IF T KLW T R V A+ SLKKLG DY+DL+++H P +
Sbjct: 82 IFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
Frame = +2
Query: 500 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI--KPDA 673
+P N + + + TW +E + G+VK +G+SNFN++QLE +L + + KP +
Sbjct: 10 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 69
Query: 674 XQIEVHLQNVQKEMVEFCQSEGVVVMGYXLXG 769
Q+E H Q ++++FCQ +V+ Y G
Sbjct: 70 NQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 101
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 44.8 bits (101), Expect = 4e-04
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +2
Query: 539 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 664
VD TW +E + G+ K IG+SNFN++QLE +L + +K
Sbjct: 19 VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +2
Query: 401 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 514
+W T R V + + SLKKL L Y+DLYL H+P+ L
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.9 bits (84), Expect = 0.048
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +2
Query: 242 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 415
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 416 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 586
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 587 GIVKGIGLSNFNKQQLERVLKEGTIKPDAXQIEV 688
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AF007190-1|AAC02268.1| 513|Homo sapiens intestinal mucin protein.
Length = 513
Score = 31.5 bits (68), Expect = 4.2
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Frame = -1
Query: 381 SSLLTTPSSTFIFTASPISCSVS*TEAVSK*RYPTSMARI-TTSRSCLSLDFTTPF*SNP 205
SSLLTT ST+ F++S + S T + P S I TT+ S L+ TT F ++P
Sbjct: 273 SSLLTTFPSTYSFSSSMSASSAGTTHTETISSLPASTNTIHTTAESALAPTTTTSFTTSP 332
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,065,596
Number of Sequences: 237096
Number of extensions: 2514143
Number of successful extensions: 9268
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 8805
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9109
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11270645666
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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