Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP07_F_D02
(866 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC004460-1|AAH04460.1| 293|Homo sapiens caspase 6, apoptosis-re... 122 2e-27
BC000305-1|AAH00305.1| 293|Homo sapiens caspase 6, apoptosis-re... 122 2e-27
AY254046-1|AAO63494.1| 293|Homo sapiens caspase 6, apoptosis-re... 122 2e-27
U20536-1|AAC50168.1| 293|Homo sapiens cysteine protease Mch2 is... 119 2e-26
AF111345-1|AAD28403.1| 522|Homo sapiens caspase-10/d protein. 116 1e-25
U86214-1|AAB46730.1| 521|Homo sapiens Fas-associated death doma... 115 2e-25
EF050529-1|ABJ53426.1| 522|Homo sapiens caspase 10, apoptosis-r... 115 2e-25
BC042844-1|AAH42844.1| 522|Homo sapiens CASP10 protein protein. 115 2e-25
AC007283-1|AAY24291.1| 522|Homo sapiens unknown protein. 115 2e-25
AB038979-1|BAB32554.1| 521|Homo sapiens caspase-10b protein. 115 2e-25
U67320-1|AAC51153.1| 303|Homo sapiens Lice2 gamma cysteine prot... 113 1e-24
U67319-1|AAC51152.1| 336|Homo sapiens Lice2 beta cysteine prote... 113 1e-24
U67206-1|AAF21460.1| 303|Homo sapiens Lice2 alpha protein. 113 1e-24
U40281-1|AAC50352.1| 303|Homo sapiens CMH-1 protein. 113 1e-24
U37448-1|AAC50303.1| 303|Homo sapiens Mch3 isoform alpha protein. 113 1e-24
BT006683-1|AAP35329.1| 303|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
BC015799-1|AAH15799.1| 303|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
AL627395-3|CAI16006.1| 222|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
AL627395-1|CAI16004.1| 303|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
AL592546-5|CAI12640.1| 222|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
AL592546-3|CAI12638.1| 303|Homo sapiens caspase 7, apoptosis-re... 113 1e-24
U60519-1|AAC50644.1| 479|Homo sapiens apoptotic cysteine protea... 111 2e-24
AJ487679-1|CAD32372.1| 478|Homo sapiens caspase 10 protein. 111 2e-24
AB038979-2|BAB32553.1| 479|Homo sapiens caspase-10a protein. 111 2e-24
U39613-1|AAC50346.1| 303|Homo sapiens ICE-LAP3 protein. 110 6e-24
U60520-1|AAC50645.1| 496|Homo sapiens apoptotic cysteine protea... 108 3e-23
AF009620-1|AAB70913.1| 464|Homo sapiens apoptotic caspase Mch5-... 108 3e-23
AB038985-1|BAB32555.1| 496|Homo sapiens caspase-8 protein. 108 3e-23
X98173-1|CAA66854.1| 464|Homo sapiens MACH-alpha-2 protein. 104 4e-22
X98172-1|CAA66853.1| 479|Homo sapiens MACH-alpha-1 protein. 104 4e-22
U58143-1|AAC50602.1| 479|Homo sapiens FADD-homologous ICE/CED-3... 104 4e-22
DQ355026-1|ABC67468.1| 496|Homo sapiens caspase 8, apoptosis-re... 104 4e-22
AF422925-1|AAL87628.1| 538|Homo sapiens procaspase-8L protein. 104 4e-22
AC007256-3|AAY24225.1| 496|Homo sapiens unknown protein. 104 4e-22
AF102146-1|AAD24962.1| 479|Homo sapiens caspase 8 protein. 103 6e-22
U26943-1|AAA74929.1| 277|Homo sapiens Yama protein protein. 99 1e-20
U13738-1|AAB60355.1| 277|Homo sapiens cysteine protease CPP32 i... 99 1e-20
U13737-1|AAA65015.1| 277|Homo sapiens cysteine protease CPP32 i... 99 1e-20
BC016926-1|AAH16926.1| 277|Homo sapiens caspase 3, apoptosis-re... 99 1e-20
AY219866-1|AAO25654.1| 277|Homo sapiens caspase 3, apoptosis-re... 99 1e-20
AJ413269-1|CAC88866.1| 277|Homo sapiens caspase-3 protein. 99 1e-20
U13021-1|AAA58959.1| 435|Homo sapiens ICH-1L protein. 89 1e-17
BT007240-1|AAP35904.1| 435|Homo sapiens caspase 2, apoptosis-re... 89 1e-17
BC002427-1|AAH02427.2| 452|Homo sapiens caspase 2, apoptosis-re... 89 1e-17
AY219042-1|AAO25653.1| 435|Homo sapiens caspase 2, apoptosis-re... 89 1e-17
AC073342-1|AAP22346.1| 435|Homo sapiens unknown protein. 89 1e-17
BT006911-1|AAP35557.1| 416|Homo sapiens caspase 9, apoptosis-re... 83 1e-15
BC006463-1|AAH06463.1| 416|Homo sapiens caspase 9, apoptosis-re... 83 1e-15
BC002452-1|AAH02452.1| 416|Homo sapiens caspase 9, apoptosis-re... 83 1e-15
AL512883-7|CAC42423.1| 416|Homo sapiens caspase 9, apoptosis-re... 83 1e-15
AL512883-5|CAI12972.1| 266|Homo sapiens caspase 9, apoptosis-re... 83 1e-15
AB209147-1|BAD92384.1| 456|Homo sapiens caspase 9 isoform alpha... 83 1e-15
X98174-1|CAA66855.1| 266|Homo sapiens MACH-alpha-3 protein. 83 1e-15
U56390-1|AAC50640.1| 416|Homo sapiens ICE-LAP6 protein. 83 2e-15
AY214168-1|AAO21133.1| 416|Homo sapiens caspase 9, apoptosis-re... 83 2e-15
AJ487678-1|CAD32371.1| 455|Homo sapiens caspase 10 protein. 83 2e-15
U13022-1|AAA58960.1| 312|Homo sapiens ICH-1S protein. 82 3e-15
CR541748-1|CAG46548.1| 312|Homo sapiens CASP2 protein. 82 3e-15
AC073342-3|AAP22347.1| 312|Homo sapiens unknown protein. 82 3e-15
AF422927-1|AAL87630.1| 339|Homo sapiens procaspase-8 protein. 81 5e-15
U60521-1|AAC50776.1| 416|Homo sapiens proMch6 protein. 81 7e-15
AB019205-1|BAA82697.1| 416|Homo sapiens Caspase-9 protein. 81 7e-15
AF422928-1|AAL87631.1| 353|Homo sapiens procaspase-8 protein. 78 4e-14
AL512883-4|CAI12971.1| 197|Homo sapiens caspase 9, apoptosis-re... 77 1e-13
U20537-1|AAC50169.1| 204|Homo sapiens cysteine protease Mch2 is... 69 3e-11
U13699-1|AAC50109.1| 263|Homo sapiens Interleukin 1-beta conver... 69 3e-11
X65019-1|CAA46153.1| 404|Homo sapiens interleukin-1B converting... 68 4e-11
U13698-1|AAC50108.1| 311|Homo sapiens interleukin 1-beta conver... 68 4e-11
U13697-1|AAC50107.1| 383|Homo sapiens Interleukin 1-beta conver... 68 4e-11
M87507-1|AAA66942.1| 404|Homo sapiens interleukin 1-beta conver... 68 4e-11
BC062327-1|AAH62327.1| 311|Homo sapiens caspase 1, apoptosis-re... 68 4e-11
BC041689-1|AAH41689.1| 380|Homo sapiens CASP1 protein protein. 68 4e-11
AY660536-1|AAT72297.1| 365|Homo sapiens caspase-1 isoform zeta ... 68 4e-11
AK223503-1|BAD97223.1| 404|Homo sapiens caspase 1 isoform alpha... 68 4e-11
U37449-1|AAC50304.1| 253|Homo sapiens Mch3 isoform beta protein. 67 9e-11
AL627395-2|CAI16005.1| 253|Homo sapiens caspase 7, apoptosis-re... 67 9e-11
AL592546-4|CAI12639.1| 253|Homo sapiens caspase 7, apoptosis-re... 67 9e-11
BC103869-1|AAI03870.1| 242|Homo sapiens caspase 14, apoptosis-r... 66 2e-10
BC103868-1|AAI03869.1| 242|Homo sapiens caspase 14, apoptosis-r... 66 2e-10
BC069541-1|AAH69541.1| 242|Homo sapiens caspase 14, apoptosis-r... 66 2e-10
AF097874-1|AAD16173.1| 242|Homo sapiens caspase 14 precursor pr... 66 2e-10
X94993-1|CAA64450.1| 364|Homo sapiens TY protease protein. 64 5e-10
U28015-1|AAA75172.1| 418|Homo sapiens cysteine protease protein. 64 5e-10
DQ508420-1|ABF47103.1| 418|Homo sapiens caspase 5, apoptosis-re... 64 5e-10
DQ228677-1|ABB58703.1| 447|Homo sapiens caspase-5/f protein. 64 5e-10
DQ228674-1|ABB58700.1| 292|Homo sapiens caspase-5/c protein. 64 5e-10
DQ228673-1|ABB58699.1| 376|Homo sapiens caspase-5/b protein. 64 5e-10
DQ228672-1|ABB58698.1| 434|Homo sapiens caspase-5/a protein. 64 5e-10
BC074994-1|AAH74994.1| 418|Homo sapiens caspase 5, apoptosis-re... 64 5e-10
BC113406-1|AAI13407.1| 418|Homo sapiens caspase 5, apoptosis-re... 64 6e-10
Z48810-1|CAA88750.1| 377|Homo sapiens TX protease precursor pro... 63 1e-09
U28979-2|AAC99854.1| 286|Homo sapiens Mih1/TX isoform delta pro... 63 1e-09
U28978-1|AAC99852.1| 321|Homo sapiens Mih1/TX isoform gamma pro... 63 1e-09
U28977-1|AAC99851.1| 331|Homo sapiens Mih1/TX isoform beta prot... 63 1e-09
U28976-1|AAC99850.1| 377|Homo sapiens Mih1/TX isoform alpha pro... 63 1e-09
U28014-1|AAA75171.1| 377|Homo sapiens cysteine protease protein. 63 1e-09
U25804-1|AAA86890.1| 377|Homo sapiens Ich-2 protein. 63 1e-09
EF636667-1|ABR09278.1| 377|Homo sapiens caspase 4, apoptosis-re... 63 1e-09
BC017839-1|AAH17839.1| 377|Homo sapiens caspase 4, apoptosis-re... 63 1e-09
AY358222-1|AAQ88589.1| 341|Homo sapiens CASP12P1 protein. 58 4e-08
AF078533-1|AAC28380.1| 377|Homo sapiens evolutionarily related ... 56 2e-07
AL050391-1|CAB43686.2| 104|Homo sapiens hypothetical protein pr... 52 3e-06
Y14039-1|CAA74366.1| 480|Homo sapiens CASH alpha protein protein. 49 2e-05
U97074-1|AAC51622.1| 480|Homo sapiens FLICE-like inhibitory pro... 49 2e-05
U85059-1|AAB82648.1| 480|Homo sapiens MRIT-alpha-1 protein. 49 2e-05
BT006751-1|AAP35397.1| 480|Homo sapiens CASP8 and FADD-like apo... 49 2e-05
BC001602-1|AAH01602.1| 480|Homo sapiens CASP8 and FADD-like apo... 49 2e-05
AF041462-1|AAB99794.1| 348|Homo sapiens I-FLICE isoform 5 protein. 49 2e-05
AF041461-1|AAB99793.1| 442|Homo sapiens I-FLICE isoform 4 protein. 49 2e-05
AF041460-1|AAB99792.1| 449|Homo sapiens I-FLICE isoform 3 protein. 49 2e-05
AF041459-1|AAB99791.1| 235|Homo sapiens I-FLICE isoform 2 protein. 49 2e-05
AF041458-1|AAB99790.1| 480|Homo sapiens I-FLICE protein. 49 2e-05
AF015451-1|AAC16440.1| 462|Homo sapiens Usurpin-beta protein. 49 2e-05
AF015450-1|AAC16439.1| 480|Homo sapiens Usurpin-alpha protein. 49 2e-05
AF010127-1|AAB64110.1| 480|Homo sapiens Casper protein. 49 2e-05
AF009618-1|AAB70911.1| 480|Homo sapiens FLAME-1-gamma protein. 49 2e-05
AF009616-1|AAB70909.1| 445|Homo sapiens FLAME-1 protein. 49 2e-05
AC007283-2|AAY24290.1| 480|Homo sapiens unknown protein. 49 2e-05
AB038972-1|BAB32552.1| 462|Homo sapiens usurpin beta protein. 49 2e-05
AF005774-1|AAC15825.1| 480|Homo sapiens caspase-like apoptosis ... 48 6e-05
AL627395-4|CAI16007.1| 220|Homo sapiens caspase 7, apoptosis-re... 44 5e-04
AL592546-6|CAI12641.1| 220|Homo sapiens caspase 7, apoptosis-re... 44 5e-04
AL512883-8|CAI12974.1| 254|Homo sapiens caspase 9, apoptosis-re... 36 0.19
AL831992-1|CAD89916.1| 798|Homo sapiens hypothetical protein pr... 32 2.4
>BC004460-1|AAH04460.1| 293|Homo sapiens caspase 6,
apoptosis-related cysteine peptidase protein.
Length = 293
Score = 122 bits (294), Expect = 2e-27
Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 1/157 (0%)
Frame = +2
Query: 281 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 457
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 458 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 637
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 638 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD 748
+ L F DKC +L GKPK+F IQAC+G++ D
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHD 169
>BC000305-1|AAH00305.1| 293|Homo sapiens caspase 6,
apoptosis-related cysteine peptidase protein.
Length = 293
Score = 122 bits (294), Expect = 2e-27
Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 1/157 (0%)
Frame = +2
Query: 281 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 457
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 458 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 637
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 638 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD 748
+ L F DKC +L GKPK+F IQAC+G++ D
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHD 169
>AY254046-1|AAO63494.1| 293|Homo sapiens caspase 6,
apoptosis-related cysteine protease protein.
Length = 293
Score = 122 bits (294), Expect = 2e-27
Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 1/157 (0%)
Frame = +2
Query: 281 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 457
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 458 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 637
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 638 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD 748
+ L F DKC +L GKPK+F IQAC+G++ D
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHD 169
>U20536-1|AAC50168.1| 293|Homo sapiens cysteine protease Mch2
isoform alpha protein.
Length = 293
Score = 119 bits (286), Expect = 2e-26
Identities = 61/157 (38%), Positives = 87/157 (55%), Gaps = 1/157 (0%)
Frame = +2
Query: 281 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 457
A G ++ + K + A Y M+H RG+A+IFNHE F H L R T D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRRTCADRD 72
Query: 458 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 637
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 638 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD 748
+ L F DKC +L GKPK+F IQAC+G++ D
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHD 169
>AF111345-1|AAD28403.1| 522|Homo sapiens caspase-10/d protein.
Length = 522
Score = 116 bits (278), Expect = 1e-25
Identities = 66/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSEASTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
I++
Sbjct: 409 SISI 412
>U86214-1|AAB46730.1| 521|Homo sapiens Fas-associated death domain
protein interleukin-1b-converting enzyme 2 protein.
Length = 521
Score = 115 bits (277), Expect = 2e-25
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
+++
Sbjct: 409 SVSI 412
>EF050529-1|ABJ53426.1| 522|Homo sapiens caspase 10,
apoptosis-related cysteine peptidase protein.
Length = 522
Score = 115 bits (277), Expect = 2e-25
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
+++
Sbjct: 409 SVSI 412
>BC042844-1|AAH42844.1| 522|Homo sapiens CASP10 protein protein.
Length = 522
Score = 115 bits (277), Expect = 2e-25
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
+++
Sbjct: 409 SVSI 412
>AC007283-1|AAY24291.1| 522|Homo sapiens unknown protein.
Length = 522
Score = 115 bits (277), Expect = 2e-25
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
+++
Sbjct: 409 SVSI 412
>AB038979-1|BAB32554.1| 521|Homo sapiens caspase-10b protein.
Length = 521
Score = 115 bits (277), Expect = 2e-25
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 218 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 397
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 398 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 574
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 575 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDG 751
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG+++
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQP 408
Query: 752 GITL 763
+++
Sbjct: 409 SVSI 412
>U67320-1|AAC51153.1| 303|Homo sapiens Lice2 gamma cysteine
protease protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>U67319-1|AAC51152.1| 336|Homo sapiens Lice2 beta cysteine protease
protein.
Length = 336
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 91 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 150
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 151 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 210
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 211 PKLFFIQACRGTELDDGI 228
>U67206-1|AAF21460.1| 303|Homo sapiens Lice2 alpha protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>U40281-1|AAC50352.1| 303|Homo sapiens CMH-1 protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>U37448-1|AAC50303.1| 303|Homo sapiens Mch3 isoform alpha protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>BT006683-1|AAP35329.1| 303|Homo sapiens caspase 7,
apoptosis-related cysteine protease protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>BC015799-1|AAH15799.1| 303|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>AL627395-3|CAI16006.1| 222|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 222
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>AL627395-1|CAI16004.1| 303|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>AL592546-5|CAI12640.1| 222|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 222
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>AL592546-3|CAI12638.1| 303|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 303
Score = 113 bits (271), Expect = 1e-24
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD GI
Sbjct: 178 PKLFFIQACRGTELDDGI 195
>U60519-1|AAC50644.1| 479|Homo sapiens apoptotic cysteine protease
Mch4 protein.
Length = 479
Score = 111 bits (268), Expect = 2e-24
Identities = 56/142 (39%), Positives = 86/142 (60%), Gaps = 2/142 (1%)
Frame = +2
Query: 344 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 524 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 697
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 698 GKPKLFFIQACQGDKLDGGITL 763
KPKLFFIQACQG+++ +++
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSI 369
>AJ487679-1|CAD32372.1| 478|Homo sapiens caspase 10 protein.
Length = 478
Score = 111 bits (268), Expect = 2e-24
Identities = 56/142 (39%), Positives = 86/142 (60%), Gaps = 2/142 (1%)
Frame = +2
Query: 344 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 524 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 697
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 698 GKPKLFFIQACQGDKLDGGITL 763
KPKLFFIQACQG+++ +++
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSI 369
>AB038979-2|BAB32553.1| 479|Homo sapiens caspase-10a protein.
Length = 479
Score = 111 bits (268), Expect = 2e-24
Identities = 56/142 (39%), Positives = 86/142 (60%), Gaps = 2/142 (1%)
Frame = +2
Query: 344 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 524 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 697
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 698 GKPKLFFIQACQGDKLDGGITL 763
KPKLFFIQACQG+++ +++
Sbjct: 348 EKPKLFFIQACQGEEIQPSVSI 369
>U39613-1|AAC50346.1| 303|Homo sapiens ICE-LAP3 protein.
Length = 303
Score = 110 bits (265), Expect = 6e-24
Identities = 55/138 (39%), Positives = 81/138 (58%), Gaps = 1/138 (0%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 703
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 704 PKLFFIQACQGDKLDGGI 757
PKLFFIQAC+G +LD I
Sbjct: 178 PKLFFIQACRGTELDDAI 195
>U60520-1|AAC50645.1| 496|Homo sapiens apoptotic cysteine protease
Mch5 isoform alpha protein.
Length = 496
Score = 108 bits (259), Expect = 3e-23
Identities = 57/152 (37%), Positives = 84/152 (55%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 302
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 391
>AF009620-1|AAB70913.1| 464|Homo sapiens apoptotic caspase
Mch5-beta protein.
Length = 464
Score = 108 bits (259), Expect = 3e-23
Identities = 57/152 (37%), Positives = 84/152 (55%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 270
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 331 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 359
>AB038985-1|BAB32555.1| 496|Homo sapiens caspase-8 protein.
Length = 496
Score = 108 bits (259), Expect = 3e-23
Identities = 57/152 (37%), Positives = 84/152 (55%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F + H
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHH 302
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 391
>X98173-1|CAA66854.1| 464|Homo sapiens MACH-alpha-2 protein.
Length = 464
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 270
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 331 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 359
>X98172-1|CAA66853.1| 479|Homo sapiens MACH-alpha-1 protein.
Length = 479
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 345
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 374
>U58143-1|AAC50602.1| 479|Homo sapiens FADD-homologous
ICE/CED-3-like protease protein.
Length = 479
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEPPIYELTSQFTGLKC 345
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 374
>DQ355026-1|ABC67468.1| 496|Homo sapiens caspase 8,
apoptosis-related cysteine peptidase protein.
Length = 496
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 302
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 391
>AF422925-1|AAL87628.1| 538|Homo sapiens procaspase-8L protein.
Length = 538
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 285 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 344
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 345 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 404
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 405 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 433
>AC007256-3|AAY24225.1| 496|Homo sapiens unknown protein.
Length = 496
Score = 104 bits (250), Expect = 4e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 243 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 302
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 303 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 362
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 363 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 391
>AF102146-1|AAD24962.1| 479|Homo sapiens caspase 8 protein.
Length = 479
Score = 103 bits (248), Expect = 6e-22
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 9/152 (5%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYDILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEPPIYELTSQFTGLKC 345
Query: 686 PTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 346 PSLAGKPKVFFIQACQGDNYQKGIPV---ETD 374
>U26943-1|AAA74929.1| 277|Homo sapiens Yama protein protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>U13738-1|AAB60355.1| 277|Homo sapiens cysteine protease CPP32
isoform beta protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>U13737-1|AAA65015.1| 277|Homo sapiens cysteine protease CPP32
isoform alpha protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>BC016926-1|AAH16926.1| 277|Homo sapiens caspase 3,
apoptosis-related cysteine peptidase protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>AY219866-1|AAO25654.1| 277|Homo sapiens caspase 3,
apoptosis-related cysteine protease protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>AJ413269-1|CAC88866.1| 277|Homo sapiens caspase-3 protein.
Length = 277
Score = 99 bits (238), Expect = 1e-20
Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y M++ G+ II N+++F + + SR+GT+VD+ +L + R L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Query: 530 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 709
++ +S+ DH+ + +LSHGE G+++ + + +F D+C +L GKPK
Sbjct: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
Query: 710 LFFIQACQGDKLDGGI 757
LF IQAC+G +LD GI
Sbjct: 157 LFIIQACRGTELDCGI 172
>U13021-1|AAA58959.1| 435|Homo sapiens ICH-1L protein.
Length = 435
Score = 89.4 bits (212), Expect = 1e-17
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 3/138 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 704 PKLFFIQACQGDKLDGGI 757
PK+FFIQAC+GD+ D G+
Sbjct: 295 PKMFFIQACRGDETDRGV 312
>BT007240-1|AAP35904.1| 435|Homo sapiens caspase 2,
apoptosis-related cysteine protease (neural precursor
cell expressed protein.
Length = 435
Score = 89.4 bits (212), Expect = 1e-17
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 3/138 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 704 PKLFFIQACQGDKLDGGI 757
PK+FFIQAC+GD+ D G+
Sbjct: 295 PKMFFIQACRGDETDRGV 312
>BC002427-1|AAH02427.2| 452|Homo sapiens caspase 2,
apoptosis-related cysteine peptidase (neural precursor
cell expresse protein.
Length = 452
Score = 89.4 bits (212), Expect = 1e-17
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 3/138 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 192 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 251
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 252 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 311
Query: 704 PKLFFIQACQGDKLDGGI 757
PK+FFIQAC+GD+ D G+
Sbjct: 312 PKMFFIQACRGDETDRGV 329
>AY219042-1|AAO25653.1| 435|Homo sapiens caspase 2,
apoptosis-related cysteine protease (neural precursor
cell expressed protein.
Length = 435
Score = 89.4 bits (212), Expect = 1e-17
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 3/138 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 704 PKLFFIQACQGDKLDGGI 757
PK+FFIQAC+GD+ D G+
Sbjct: 295 PKMFFIQACRGDETDRGV 312
>AC073342-1|AAP22346.1| 435|Homo sapiens unknown protein.
Length = 435
Score = 89.4 bits (212), Expect = 1e-17
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 3/138 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 175 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 234
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 235 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 294
Query: 704 PKLFFIQACQGDKLDGGI 757
PK+FFIQAC+GD+ D G+
Sbjct: 295 PKMFFIQACRGDETDRGV 312
>BT006911-1|AAP35557.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine protease protein.
Length = 416
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>BC006463-1|AAH06463.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>BC002452-1|AAH02452.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AL512883-7|CAC42423.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 416
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AL512883-5|CAI12972.1| 266|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 266
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 78 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 137
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 138 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 197
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 198 LFFIQACGGEQKDHGFEVASTSPE 221
>AB209147-1|BAD92384.1| 456|Homo sapiens caspase 9 isoform alpha
preproprotein variant protein.
Length = 456
Score = 83.4 bits (197), Expect = 1e-15
Identities = 49/144 (34%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 196 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 255
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 256 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 315
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 316 LFFIQACGGEQKDHGFEVASTSPE 339
>X98174-1|CAA66855.1| 266|Homo sapiens MACH-alpha-3 protein.
Length = 266
Score = 83.0 bits (196), Expect = 1e-15
Identities = 44/109 (40%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = +2
Query: 458 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 637
+L+ L F + + E I ++ MDH++ DC + +LSHG+ G++Y D
Sbjct: 56 ALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDG 115
Query: 638 HYKPD-NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSXTETD 781
P L FT KCP+LAGKPK+FFIQACQGD GI + ETD
Sbjct: 116 QEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPV---ETD 161
>U56390-1|AAC50640.1| 416|Homo sapiens ICE-LAP6 protein.
Length = 416
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 RQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AY214168-1|AAO21133.1| 416|Homo sapiens caspase 9,
apoptosis-related cysteine protease protein.
Length = 416
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 RQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AJ487678-1|CAD32371.1| 455|Homo sapiens caspase 10 protein.
Length = 455
Score = 82.6 bits (195), Expect = 2e-15
Identities = 40/106 (37%), Positives = 64/106 (60%), Gaps = 2/106 (1%)
Frame = +2
Query: 452 SDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYA 628
++ LS V + LGF+V + +N+ ++ +Q Q H D DC + +L+HG G +Y+
Sbjct: 240 NEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYS 299
Query: 629 KDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL 763
D P + +FTA +CP LA KPKLFFIQACQG+++ +++
Sbjct: 300 SDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSI 345
>U13022-1|AAA58960.1| 312|Homo sapiens ICH-1S protein.
Length = 312
Score = 81.8 bits (193), Expect = 3e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 704 PKLFFIQACQG 736
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>CR541748-1|CAG46548.1| 312|Homo sapiens CASP2 protein.
Length = 312
Score = 81.8 bits (193), Expect = 3e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 704 PKLFFIQACQG 736
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>AC073342-3|AAP22347.1| 312|Homo sapiens unknown protein.
Length = 312
Score = 81.8 bits (193), Expect = 3e-15
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 529
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 161 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 220
Query: 530 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 703
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 221 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 280
Query: 704 PKLFFIQACQG 736
PK+FFIQAC+G
Sbjct: 281 PKMFFIQACRG 291
>AF422927-1|AAL87630.1| 339|Homo sapiens procaspase-8 protein.
Length = 339
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 9/129 (6%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 211 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 270
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 271 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 330
Query: 686 PTLAGKPKL 712
P+LAGKPK+
Sbjct: 331 PSLAGKPKV 339
>U60521-1|AAC50776.1| 416|Homo sapiens proMch6 protein.
Length = 416
Score = 80.6 bits (190), Expect = 7e-15
Identities = 48/144 (33%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSPHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AB019205-1|BAA82697.1| 416|Homo sapiens Caspase-9 protein.
Length = 416
Score = 80.6 bits (190), Expect = 7e-15
Identities = 48/144 (33%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSPHFMVEVKGDLTAKKMVLALLELA 220
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 710 LFFIQACQGDKLDGGITLSXTETD 781
LFFIQAC G++ D G ++ T +
Sbjct: 281 LFFIQACGGEQKDHGFEVASTSPE 304
>AF422928-1|AAL87631.1| 353|Homo sapiens procaspase-8 protein.
Length = 353
Score = 78.2 bits (184), Expect = 4e-14
Identities = 41/128 (32%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
Frame = +2
Query: 353 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 508
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 685
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT C
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGFGC 345
Query: 686 PTLAGKPK 709
P+LAGKPK
Sbjct: 346 PSLAGKPK 353
>AL512883-4|CAI12971.1| 197|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 197
Score = 76.6 bits (180), Expect = 1e-13
Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 9/129 (6%)
Frame = +2
Query: 377 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 553
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 2 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 61
Query: 554 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 709
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 62 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 121
Query: 710 LFFIQACQG 736
LFFIQAC G
Sbjct: 122 LFFIQACGG 130
>U20537-1|AAC50169.1| 204|Homo sapiens cysteine protease Mch2
isoform beta protein.
Length = 204
Score = 68.5 bits (160), Expect = 3e-11
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 518 AEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLA 697
A + R +S + H D DC + LSHGE +YA D + L F DKC +L
Sbjct: 4 ASGLRRGHPAVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 63
Query: 698 GKPKLFFIQACQGDKLD 748
GKPK+F IQAC+G++ D
Sbjct: 64 GKPKIFIIQACRGNQHD 80
>U13699-1|AAC50109.1| 263|Homo sapiens Interleukin 1-beta
converting enzyme isoform delta protein.
Length = 263
Score = 68.5 bits (160), Expect = 3e-11
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 719 IQACQGDKL 745
IQAC+GD +
Sbjct: 189 IQACRGDNV 197
>X65019-1|CAA46153.1| 404|Homo sapiens interleukin-1B converting
enzyme protein.
Length = 404
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 282 IQACRGD 288
>U13698-1|AAC50108.1| 311|Homo sapiens interleukin 1-beta
converting enzyme isoform gamma protein.
Length = 311
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 189 IQACRGD 195
>U13697-1|AAC50107.1| 383|Homo sapiens Interleukin 1-beta
converting enzyme isoform beta protein.
Length = 383
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 143 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 200
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 201 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 260
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 261 IQACRGD 267
>M87507-1|AAA66942.1| 404|Homo sapiens interleukin 1-beta
convertase protein.
Length = 404
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 282 IQACRGD 288
>BC062327-1|AAH62327.1| 311|Homo sapiens caspase 1,
apoptosis-related cysteine peptidase (interleukin 1,
beta, convertas protein.
Length = 311
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 189 IQACRGD 195
>BC041689-1|AAH41689.1| 380|Homo sapiens CASP1 protein protein.
Length = 380
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 140 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 197
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 198 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 257
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 258 IQACRGD 264
>AY660536-1|AAT72297.1| 365|Homo sapiens caspase-1 isoform zeta
precursor protein.
Length = 365
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 125 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 182
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 183 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 242
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 243 IQACRGD 249
>AK223503-1|BAD97223.1| 404|Homo sapiens caspase 1 isoform alpha
precursor variant protein.
Length = 404
Score = 68.1 bits (159), Expect = 4e-11
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Frame = +2
Query: 380 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 559
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 560 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 718
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 719 IQACQGD 739
IQAC+GD
Sbjct: 282 IQACRGD 288
>U37449-1|AAC50304.1| 253|Homo sapiens Mch3 isoform beta protein.
Length = 253
Score = 66.9 bits (156), Expect = 9e-11
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 619
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>AL627395-2|CAI16005.1| 253|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 253
Score = 66.9 bits (156), Expect = 9e-11
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 619
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>AL592546-4|CAI12639.1| 253|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 253
Score = 66.9 bits (156), Expect = 9e-11
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 523
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 524 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 619
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>BC103869-1|AAI03870.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Frame = +2
Query: 425 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 595
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 596 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSXT 772
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 773 E 775
E
Sbjct: 147 E 147
>BC103868-1|AAI03869.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Frame = +2
Query: 425 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 595
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 596 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSXT 772
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 773 E 775
E
Sbjct: 147 E 147
>BC069541-1|AAH69541.1| 242|Homo sapiens caspase 14,
apoptosis-related cysteine peptidase protein.
Length = 242
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Frame = +2
Query: 425 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 595
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 596 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSXT 772
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 773 E 775
E
Sbjct: 147 E 147
>AF097874-1|AAD16173.1| 242|Homo sapiens caspase 14 precursor
protein.
Length = 242
Score = 65.7 bits (153), Expect = 2e-10
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Frame = +2
Query: 425 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 595
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 596 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSXT 772
++HG G L +D K +NL+ C L KPK++ IQAC+G++ D G T+
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGD 146
Query: 773 E 775
E
Sbjct: 147 E 147
>X94993-1|CAA64450.1| 364|Homo sapiens TY protease protein.
Length = 364
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 120 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 177
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 178 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 237
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 238 KVIIVQACRGEK 249
>U28015-1|AAA75172.1| 418|Homo sapiens cysteine protease protein.
Length = 418
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 292 KVIIVQACRGEK 303
>DQ508420-1|ABF47103.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 292 KVIIVQACRGEK 303
>DQ228677-1|ABB58703.1| 447|Homo sapiens caspase-5/f protein.
Length = 447
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 203 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 260
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 261 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 320
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 321 KVIIVQACRGEK 332
>DQ228674-1|ABB58700.1| 292|Homo sapiens caspase-5/c protein.
Length = 292
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 48 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 105
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 106 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 165
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 166 KVIIVQACRGEK 177
>DQ228673-1|ABB58699.1| 376|Homo sapiens caspase-5/b protein.
Length = 376
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 132 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 189
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 190 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 249
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 250 KVIIVQACRGEK 261
>DQ228672-1|ABB58698.1| 434|Homo sapiens caspase-5/a protein.
Length = 434
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 190 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 247
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 248 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 307
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 308 KVIIVQACRGEK 319
>BC074994-1|AAH74994.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 64.5 bits (150), Expect = 5e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 292 KVIIVQACRGEK 303
>BC113406-1|AAI13407.1| 418|Homo sapiens caspase 5,
apoptosis-related cysteine peptidase protein.
Length = 418
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/132 (30%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Frame = +2
Query: 368 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 547
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDILGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 548 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 706
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 707 KLFFIQACQGDK 742
K+ +QAC+G+K
Sbjct: 292 KVIIVQACRGEK 303
>Z48810-1|CAA88750.1| 377|Homo sapiens TX protease precursor
protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>U28979-2|AAC99854.1| 286|Homo sapiens Mih1/TX isoform delta
protein.
Length = 286
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 4 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 61
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 62 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 121
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 122 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 169
>U28978-1|AAC99852.1| 321|Homo sapiens Mih1/TX isoform gamma
protein.
Length = 321
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 39 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 96
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 97 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 156
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 157 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 204
>U28977-1|AAC99851.1| 331|Homo sapiens Mih1/TX isoform beta
protein.
Length = 331
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 49 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 106
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 107 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 166
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 167 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 214
>U28976-1|AAC99850.1| 377|Homo sapiens Mih1/TX isoform alpha
protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>U28014-1|AAA75171.1| 377|Homo sapiens cysteine protease protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>U25804-1|AAA86890.1| 377|Homo sapiens Ich-2 protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>EF636667-1|ABR09278.1| 377|Homo sapiens caspase 4,
apoptosis-related cysteine peptidase protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>BC017839-1|AAH17839.1| 377|Homo sapiens caspase 4,
apoptosis-related cysteine peptidase protein.
Length = 377
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +2
Query: 260 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 433
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 434 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 610
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 611 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>AY358222-1|AAQ88589.1| 341|Homo sapiens CASP12P1 protein.
Length = 341
Score = 58.0 bits (134), Expect = 4e-08
Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 7/122 (5%)
Frame = +2
Query: 395 NHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS-EMDHTD 571
N + E + L +R G+ +D + +L LG+SV + NL A+++ ++Q + +H
Sbjct: 102 NIRNKEFNYLHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQS 161
Query: 572 NDCLLVAVLSHGEL-GMLYAKDTHYKPD-----NLWYYFTADKCPTLAGKPKLFFIQACQ 733
+D + +SH L G+ K +PD ++ F C +L KPK+ +QAC+
Sbjct: 162 SDSTFLVFMSHSILNGICGTKHWDQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACR 221
Query: 734 GD 739
G+
Sbjct: 222 GN 223
>AF078533-1|AAC28380.1| 377|Homo sapiens evolutionarily related
interleukin-1beta converting enzyme protein.
Length = 377
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Frame = +2
Query: 317 YAKMPVERYAHYYNMNH--NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 490
+ K+ ER Y + + +A+I + F+ ++ R G +D + ++L GLG+
Sbjct: 114 FLKLCKERAGEIYPIKERKDRTRLALIICNTEFD--HMPPRNGAALDILGMKQLLEGLGY 171
Query: 491 SVTVLHNLRAEDINRYIQQISEMD-HTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY 664
+V V L A D+ + + + + H +D + +SHG L G+ + +PD L Y
Sbjct: 172 TVEVEEKLTARDMESVLWKFAAREEHKSSDSTFLVFMSHGILDGICGTMHSEEEPDVLPY 231
Query: 665 -----YFTADKCPTLAGKPKLFFIQACQG 736
F C +L KPK+ +QAC+G
Sbjct: 232 DTIFRTFNNRNCLSLKDKPKVIIVQACRG 260
>AL050391-1|CAB43686.2| 104|Homo sapiens hypothetical protein
protein.
Length = 104
Score = 52.0 bits (119), Expect = 3e-06
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Frame = +2
Query: 461 LSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGEL-GMLYAKD 634
+ ++L GL +SV V NL A D+ ++ + +H +D + ++SHG L G+
Sbjct: 3 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 62
Query: 635 THYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 736
KPD L Y F C +L KPK+ +QAC+G
Sbjct: 63 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 101
>Y14039-1|CAA74366.1| 480|Homo sapiens CASH alpha protein protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>U97074-1|AAC51622.1| 480|Homo sapiens FLICE-like inhibitory
protein long form protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>U85059-1|AAB82648.1| 480|Homo sapiens MRIT-alpha-1 protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>BT006751-1|AAP35397.1| 480|Homo sapiens CASP8 and FADD-like
apoptosis regulator protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>BC001602-1|AAH01602.1| 480|Homo sapiens CASP8 and FADD-like
apoptosis regulator protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF041462-1|AAB99794.1| 348|Homo sapiens I-FLICE isoform 5 protein.
Length = 348
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 149 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 208
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 209 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 244
>AF041461-1|AAB99793.1| 442|Homo sapiens I-FLICE isoform 4 protein.
Length = 442
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 244 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 303
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 304 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 339
>AF041460-1|AAB99792.1| 449|Homo sapiens I-FLICE isoform 3 protein.
Length = 449
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF041459-1|AAB99791.1| 235|Homo sapiens I-FLICE isoform 2 protein.
Length = 235
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 18 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 77
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 78 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 113
>AF041458-1|AAB99790.1| 480|Homo sapiens I-FLICE protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF015451-1|AAC16440.1| 462|Homo sapiens Usurpin-beta protein.
Length = 462
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF015450-1|AAC16439.1| 480|Homo sapiens Usurpin-alpha protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF010127-1|AAB64110.1| 480|Homo sapiens Casper protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF009618-1|AAB70911.1| 480|Homo sapiens FLAME-1-gamma protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF009616-1|AAB70909.1| 445|Homo sapiens FLAME-1 protein.
Length = 445
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 228 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 287
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 288 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 323
>AC007283-2|AAY24290.1| 480|Homo sapiens unknown protein.
Length = 480
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AB038972-1|BAB32552.1| 462|Homo sapiens usurpin beta protein.
Length = 462
Score = 49.2 bits (112), Expect = 2e-05
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>AF005774-1|AAC15825.1| 480|Homo sapiens caspase-like apoptosis
regulatory protein protein.
Length = 480
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +2
Query: 449 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 625
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 626 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 724
D TH ++ F + CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGESCPYLAGKPKMFFIQ 358
>AL627395-4|CAI16007.1| 220|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 220
Score = 44.4 bits (100), Expect = 5e-04
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 511
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYND 113
>AL592546-6|CAI12641.1| 220|Homo sapiens caspase 7,
apoptosis-related cysteine peptidase protein.
Length = 220
Score = 44.4 bits (100), Expect = 5e-04
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +2
Query: 347 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 511
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYND 113
>AL512883-8|CAI12974.1| 254|Homo sapiens caspase 9,
apoptosis-related cysteine peptidase protein.
Length = 254
Score = 35.9 bits (79), Expect = 0.19
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Frame = +2
Query: 509 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGEL-GMLYAKD-THYKPDNLWYYFTADK 682
N+ E + R + M D L A SH + G +Y D + + F
Sbjct: 184 NIDCEKLRRRFSSLHFMVEVKGD--LTAKASHLQFPGAVYGTDGCPVSVEKIVNIFNGTS 241
Query: 683 CPTLAGKPKLFFI 721
CP+L GKPKLFFI
Sbjct: 242 CPSLGGKPKLFFI 254
>AL831992-1|CAD89916.1| 798|Homo sapiens hypothetical protein
protein.
Length = 798
Score = 32.3 bits (70), Expect = 2.4
Identities = 16/45 (35%), Positives = 24/45 (53%)
Frame = +2
Query: 203 KMADEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVE 337
++A+ E+K + EQ NG DE D G H + R +KM +E
Sbjct: 80 RLAELEEKLPVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIE 124
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,357,437
Number of Sequences: 237096
Number of extensions: 2321183
Number of successful extensions: 4517
Number of sequences better than 10.0: 124
Number of HSP's better than 10.0 without gapping: 4208
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4403
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11095746082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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