Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP05_F_J06
(941 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U95000-1|AAF88143.1| 2798|Homo sapiens hyd protein protein. 316 8e-86
AF006010-1|AAD01259.2| 2799|Homo sapiens progestin induced prote... 316 8e-86
AB020703-1|BAA74919.3| 2820|Homo sapiens KIAA0896 protein protein. 316 8e-86
BC044598-1|AAH44598.1| 79|Homo sapiens UBR5 protein protein. 96 2e-19
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 90 1e-17
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 90 1e-17
AL590402-1|CAH74023.1| 562|Homo sapiens HECT domain and ankyrin... 90 1e-17
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 90 1e-17
AL513472-1|CAH71889.1| 562|Homo sapiens HECT domain and ankyrin... 90 1e-17
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 90 1e-17
AB037741-1|BAA92558.1| 567|Homo sapiens KIAA1320 protein protein. 90 1e-17
AC007956-1|AAF61276.1| 823|Homo sapiens KIAA0317 protein. 80 1e-14
AB002315-1|BAA20775.2| 826|Homo sapiens KIAA0317 protein. 80 1e-14
BC032944-1|AAH32944.1| 789|Homo sapiens KIAA0317 protein protein. 76 2e-13
Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory elem... 76 2e-13
Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory elem... 76 2e-13
Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory eleme... 76 2e-13
Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory eleme... 76 2e-13
DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase ... 76 2e-13
CR456813-1|CAG33094.1| 308|Homo sapiens UREB1 protein. 76 2e-13
BC107576-1|AAI07577.1| 332|Homo sapiens HUWE1 protein protein. 76 2e-13
BC063505-1|AAH63505.1| 388|Homo sapiens HUWE1 protein protein. 76 2e-13
BC002602-1|AAH02602.2| 442|Homo sapiens HUWE1 protein protein. 76 2e-13
AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein. 76 2e-13
AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1 p... 76 2e-13
AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory ele... 76 2e-13
AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory ele... 76 2e-13
AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory ele... 76 2e-13
AK223167-1|BAD96887.1| 439|Homo sapiens E3 ubiquitin protein li... 76 2e-13
AF057569-1|AAC62492.1| 308|Homo sapiens upstream regulatory ele... 76 2e-13
AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LAS... 76 2e-13
AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein. 76 2e-13
D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein. 71 5e-12
AY550969-1|AAT52215.1| 900|Homo sapiens cell proliferation-indu... 71 5e-12
AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligas... 71 8e-12
AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMU... 71 8e-12
AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2 pro... 71 8e-12
AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein. 71 8e-12
BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiqui... 68 4e-11
BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiqui... 68 4e-11
BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein. 68 4e-11
AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smu... 68 4e-11
AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMU... 68 4e-11
AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMU... 68 4e-11
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 64 9e-10
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 64 9e-10
DQ181796-1|ABA10330.1| 834|Homo sapiens NEDD4L variant protein. 63 2e-09
BC032597-1|AAH32597.1| 911|Homo sapiens NEDD4L protein protein. 63 2e-09
BC019345-1|AAH19345.1| 855|Homo sapiens Unknown (protein for IM... 63 2e-09
BC000621-1|AAH00621.2| 855|Homo sapiens NEDD4L protein protein. 63 2e-09
AY312514-1|AAP75706.1| 975|Homo sapiens NEDD4.2 protein. 63 2e-09
AY112985-1|AAM76730.1| 947|Homo sapiens ubiquitin ligase NEDD4h... 63 2e-09
AY112984-1|AAM76729.1| 967|Homo sapiens ubiquitin ligase NEDD4g... 63 2e-09
AY112983-1|AAM76728.1| 854|Homo sapiens ubiquitin ligase NEDD4f... 63 2e-09
AL137469-1|CAB70754.1| 820|Homo sapiens hypothetical protein pr... 63 2e-09
AF385931-1|AAM46208.1| 854|Homo sapiens ubiquitin ligase NEDD4L... 63 2e-09
AF210730-1|AAG43524.1| 854|Homo sapiens NEDD4La protein. 63 2e-09
AB071179-1|BAB69424.1| 955|Homo sapiens NEDD4-like ubiquitin li... 63 2e-09
AB007899-1|BAA23711.1| 995|Homo sapiens KIAA0439 protein. 63 2e-09
BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein. 62 4e-09
AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiqui... 62 4e-09
AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiqui... 62 4e-09
AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiqui... 62 4e-09
AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiqui... 62 4e-09
AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligas... 62 4e-09
AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting ... 62 4e-09
AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiqui... 62 4e-09
AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligas... 62 4e-09
X98033-1|CAA66656.1| 852|Homo sapiens E6-AP protein. 60 9e-09
X98032-1|CAA66655.1| 852|Homo sapiens E6-AP protein. 60 9e-09
X98031-1|CAA66654.1| 852|Homo sapiens E6-AP protein. 60 9e-09
X98021-1|CAA66653.1| 852|Homo sapiens E6-AP protein. 60 9e-09
U84404-1|AAB49301.1| 852|Homo sapiens E6-associated protein E6-... 60 9e-09
BC009271-1|AAH09271.1| 585|Homo sapiens UBE3A protein protein. 60 9e-09
AF273050-1|AAG34910.1| 852|Homo sapiens CTCL tumor antigen se37... 60 9e-09
AF016708-1|AAB69154.1| 852|Homo sapiens E6-AP ubiquitin-protein... 60 9e-09
BC002582-1|AAH02582.2| 872|Homo sapiens ubiquitin protein ligas... 60 1e-08
AB194232-2|BAD69554.1| 852|Homo sapiens ubiquitin ligase E3A is... 58 4e-08
L07557-1|AAA35542.1| 874|Homo sapiens oncogenic protein-associa... 58 5e-08
BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain ... 57 1e-07
AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin li... 57 1e-07
AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein. 57 1e-07
D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein. 56 1e-07
BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain ... 56 1e-07
BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain ... 56 1e-07
AC004975-1|AAD51453.1| 415|Homo sapiens unknown protein. 56 1e-07
AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein. 56 1e-07
BC130470-1|AAI30471.1| 577|Homo sapiens HECT domain containing ... 53 1e-06
BC126352-1|AAI26353.1| 577|Homo sapiens HECT domain containing ... 53 1e-06
BC063686-1|AAH63686.1| 347|Homo sapiens HECTD1 protein protein. 53 1e-06
BC019105-1|AAH19105.1| 210|Homo sapiens HECTD3 protein protein. 53 1e-06
BC011658-1|AAH11658.2| 520|Homo sapiens HECTD1 protein protein. 53 1e-06
AY739714-1|AAW65983.1| 1224|Homo sapiens HECTD1 protein. 53 1e-06
AY254380-1|AAP13073.1| 2612|Homo sapiens E3 ligase for inhibin r... 53 1e-06
AL359473-2|CAI16438.1| 861|Homo sapiens HECT domain containing ... 53 1e-06
AL359473-1|CAI16437.1| 471|Homo sapiens HECT domain containing ... 53 1e-06
AL110222-1|CAB53681.1| 959|Homo sapiens hypothetical protein pr... 53 1e-06
AK024809-1|BAB15015.1| 210|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AB032957-1|BAA86445.2| 2168|Homo sapiens KIAA1131 protein protein. 53 1e-06
U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein. 49 3e-05
BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein. 49 3e-05
BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3... 49 3e-05
L40383-1|AAC41731.1| 174|Homo sapiens thyroid receptor interact... 47 1e-04
D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein. 47 1e-04
BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein. 47 1e-04
BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein. 47 1e-04
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 47 1e-04
BC035775-1|AAH35775.2| 396|Homo sapiens HERC6 protein protein. 47 1e-04
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 47 1e-04
AK000644-1|BAA91303.1| 379|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 47 1e-04
AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein. 47 1e-04
BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3... 46 2e-04
BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein. 46 2e-04
AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiqui... 46 2e-04
AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing pr... 46 2e-04
U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein. 45 5e-04
BC040187-1|AAH40187.1| 776|Homo sapiens HECT domain containing ... 44 6e-04
AL834183-1|CAD38880.1| 523|Homo sapiens hypothetical protein pr... 44 6e-04
AL713675-1|CAD28480.1| 238|Homo sapiens hypothetical protein pr... 44 6e-04
AL161798-4|CAH70053.1| 776|Homo sapiens HECT domain containing ... 44 6e-04
AL161798-1|CAH70050.1| 426|Homo sapiens HECT domain containing ... 44 6e-04
AF225409-1|AAO27484.1| 306|Homo sapiens HERC2 protein. 44 6e-04
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 44 6e-04
BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligas... 37 0.093
BC032301-1|AAH32301.1| 1026|Homo sapiens UBE3B protein protein. 37 0.093
AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens ... 37 0.093
AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein. 37 0.093
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 37 0.12
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 37 0.12
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 37 0.12
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 37 0.12
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 37 0.12
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 37 0.12
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 37 0.12
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 37 0.12
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 37 0.12
BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein pr... 36 0.16
AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens ... 36 0.21
AF010403-1|AAC51734.1| 5262|Homo sapiens ALR protein. 34 0.65
Z34277-1|CAA84031.1| 477|Homo sapiens mucin protein. 34 0.86
AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein. 34 0.86
BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 33 1.1
BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein. 31 6.1
AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens ... 31 6.1
AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member... 31 6.1
AF010404-1|AAC51735.1| 4957|Homo sapiens ALR protein. 31 8.0
>U95000-1|AAF88143.1| 2798|Homo sapiens hyd protein protein.
Length = 2798
Score = 316 bits (776), Expect = 8e-86
Identities = 138/220 (62%), Positives = 180/220 (81%)
Frame = +3
Query: 54 LNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXX 233
LNRHV+K +LGR + +HD AFFDP++YESLRQL++ +++ D+ ++F+A+DL F++++C
Sbjct: 2549 LNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKE 2608
Query: 234 XXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEG 413
VELIP G + VT NVY+YVRKY++HRML+ E+ L AMR G+LDVLP+++LE
Sbjct: 2609 EGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLED 2668
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LTAED RLL+NG G++NV L+S+TSFNDESGE E+L +FKRW W+IV+KM+ ERQDL
Sbjct: 2669 LTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDL 2728
Query: 594 VYFWTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTCI 713
VYFWT SP+LPASEEGFQPMPS+TIRP DD HLPTANTCI
Sbjct: 2729 VYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCI 2768
>AF006010-1|AAD01259.2| 2799|Homo sapiens progestin induced protein
protein.
Length = 2799
Score = 316 bits (776), Expect = 8e-86
Identities = 138/220 (62%), Positives = 180/220 (81%)
Frame = +3
Query: 54 LNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXX 233
LNRHV+K +LGR + +HD AFFDP++YESLRQL++ +++ D+ ++F+A+DL F++++C
Sbjct: 2550 LNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKE 2609
Query: 234 XXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEG 413
VELIP G + VT NVY+YVRKY++HRML+ E+ L AMR G+LDVLP+++LE
Sbjct: 2610 EGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLED 2669
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LTAED RLL+NG G++NV L+S+TSFNDESGE E+L +FKRW W+IV+KM+ ERQDL
Sbjct: 2670 LTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDL 2729
Query: 594 VYFWTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTCI 713
VYFWT SP+LPASEEGFQPMPS+TIRP DD HLPTANTCI
Sbjct: 2730 VYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCI 2769
>AB020703-1|BAA74919.3| 2820|Homo sapiens KIAA0896 protein protein.
Length = 2820
Score = 316 bits (776), Expect = 8e-86
Identities = 138/220 (62%), Positives = 180/220 (81%)
Frame = +3
Query: 54 LNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXX 233
LNRHV+K +LGR + +HD AFFDP++YESLRQL++ +++ D+ ++F+A+DL F++++C
Sbjct: 2571 LNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKE 2630
Query: 234 XXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEG 413
VELIP G + VT NVY+YVRKY++HRML+ E+ L AMR G+LDVLP+++LE
Sbjct: 2631 EGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLED 2690
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LTAED RLL+NG G++NV L+S+TSFNDESGE E+L +FKRW W+IV+KM+ ERQDL
Sbjct: 2691 LTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDL 2750
Query: 594 VYFWTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTCI 713
VYFWT SP+LPASEEGFQPMPS+TIRP DD HLPTANTCI
Sbjct: 2751 VYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCI 2790
>BC044598-1|AAH44598.1| 79|Homo sapiens UBR5 protein protein.
Length = 79
Score = 95.9 bits (228), Expect = 2e-19
Identities = 41/49 (83%), Positives = 44/49 (89%)
Frame = +3
Query: 567 MTHLERQDLVYFWTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTCI 713
M+ ERQDLVYFWT SP+LPASEEGFQPMPS+TIRP DD HLPTANTCI
Sbjct: 1 MSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCI 49
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1 protein.
Length = 909
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 660 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 713
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 714 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 773
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 774 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 829
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 830 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 877
>AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1 protein.
Length = 903
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 654 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 707
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 708 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 767
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 768 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 823
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 824 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 871
>AL590402-1|CAH74023.1| 562|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 562
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 313 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 366
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 367 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 426
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 427 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 482
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 483 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 530
>AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1 protein.
Length = 903
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 654 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 707
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 708 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 767
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 768 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 823
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 824 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 871
>AL513472-1|CAH71889.1| 562|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 562
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 313 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 366
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 367 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 426
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 427 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 482
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 483 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 530
>AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1 protein.
Length = 903
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 654 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 707
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 708 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 767
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 768 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 823
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 824 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 871
>AB037741-1|BAA92558.1| 567|Homo sapiens KIAA1320 protein protein.
Length = 567
Score = 89.8 bits (213), Expect = 1e-17
Identities = 70/228 (30%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
++ R K+ILG P+ + D+A DP ++L Q ++D + D L+L FS+E
Sbjct: 318 IYFTRSFYKHILGIPVNYQDVASIDPEYAKNL-QWILDNDISD-----LGLELTFSVETD 371
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
V L PGG + VT +N +YV+ ++ RM + + + A G +P S +
Sbjct: 372 VFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLI 431
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
+ +L LLL+G+ +I+V+ + T + SG ER +W W +V+ +T ER
Sbjct: 432 QLFDEYELELLLSGMPEIDVSDWIKNTEYT--SGY--EREDPVIQWFWEVVEDITQEERV 487
Query: 588 DLVYFWTGSPALP----ASEEGFQPMPSVTIR--PADDAHLPTANTCI 713
L+ F TGS +P A+ G + + TI P LPT++TCI
Sbjct: 488 LLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 535
>AC007956-1|AAF61276.1| 823|Homo sapiens KIAA0317 protein.
Length = 823
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/219 (28%), Positives = 104/219 (47%), Gaps = 2/219 (0%)
Frame = +3
Query: 60 RHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXX 239
R L I+G + + DP Y+S +++ + + + +FA N S ++
Sbjct: 582 RSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQL----- 636
Query: 240 XXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLT 419
VEL+ GG + VT N Y+ +Q+R+ ++ +E G+ +++PE+ L
Sbjct: 637 DKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFD 696
Query: 420 AEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVY 599
+L LL+ G GDI+V+ ++ S E++ RW W +V +T E L+
Sbjct: 697 ENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKV---MRWFWTVVSSLTQEELARLLQ 753
Query: 600 FWTGSPALPASEEGFQPM-PSVTIRPA-DDAHLPTANTC 710
F TGS LP GF + PS I A + LPTA+TC
Sbjct: 754 FTTGSSQLPPG--GFAALCPSFQIIAAPTHSTLPTAHTC 790
>AB002315-1|BAA20775.2| 826|Homo sapiens KIAA0317 protein.
Length = 826
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/219 (28%), Positives = 104/219 (47%), Gaps = 2/219 (0%)
Frame = +3
Query: 60 RHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXX 239
R L I+G + + DP Y+S +++ + + + +FA N S ++
Sbjct: 585 RSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQL----- 639
Query: 240 XXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLT 419
VEL+ GG + VT N Y+ +Q+R+ ++ +E G+ +++PE+ L
Sbjct: 640 DKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFD 699
Query: 420 AEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVY 599
+L LL+ G GDI+V+ ++ S E++ RW W +V +T E L+
Sbjct: 700 ENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKV---MRWFWTVVSSLTQEELARLLQ 756
Query: 600 FWTGSPALPASEEGFQPM-PSVTIRPA-DDAHLPTANTC 710
F TGS LP GF + PS I A + LPTA+TC
Sbjct: 757 FTTGSSQLPPG--GFAALCPSFQIIAAPTHSTLPTAHTC 793
>BC032944-1|AAH32944.1| 789|Homo sapiens KIAA0317 protein protein.
Length = 789
Score = 76.2 bits (179), Expect = 2e-13
Identities = 62/218 (28%), Positives = 103/218 (47%), Gaps = 2/218 (0%)
Frame = +3
Query: 60 RHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXX 239
R L I+G + + DP Y+S +++ + + + +FA N S ++
Sbjct: 582 RSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQL----- 636
Query: 240 XXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLT 419
VEL+ GG + VT N Y+ +Q+R+ ++ +E G+ +++PE+ L
Sbjct: 637 DKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFD 696
Query: 420 AEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVY 599
+L LL+ G GDI+V+ ++ S E++ RW W +V +T E L+
Sbjct: 697 ENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKV---MRWFWTVVSSLTQEELARLLQ 753
Query: 600 FWTGSPALPASEEGFQPM-PSVTIRPA-DDAHLPTANT 707
F TGS LP GF + PS I A + LPTA+T
Sbjct: 754 FTTGSSQLPPG--GFAALCPSFQIIAAPTHSTLPTAHT 789
>Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 3160 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 3213
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 3214 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 3273
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 3274 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 3328
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 3329 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 3374
>Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 1196
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 949 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 1002
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 1003 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 1062
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 1063 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 1117
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 1118 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 1163
>Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase
protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>CR456813-1|CAG33094.1| 308|Homo sapiens UREB1 protein.
Length = 308
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 61 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 114
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 115 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 174
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 175 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 229
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 230 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 275
>BC107576-1|AAI07577.1| 332|Homo sapiens HUWE1 protein protein.
Length = 332
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 85 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 138
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 139 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 198
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 199 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 253
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 254 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 299
>BC063505-1|AAH63505.1| 388|Homo sapiens HUWE1 protein protein.
Length = 388
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 141 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 194
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 195 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 254
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 255 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 309
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 310 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 355
>BC002602-1|AAH02602.2| 442|Homo sapiens HUWE1 protein protein.
Length = 442
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 195 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 248
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 249 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 308
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 309 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 363
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 364 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 409
>AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1
protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 3160 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 3213
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 3214 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 3273
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 3274 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 3328
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 3329 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 3374
>AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 4127 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 4180
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 4181 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 4240
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 4241 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 4295
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 4296 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 4341
>AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 1196
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 949 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 1002
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 1003 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 1062
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 1063 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 1117
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 1118 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 1163
>AK223167-1|BAD96887.1| 439|Homo sapiens E3 ubiquitin protein
ligase URE-B1 variant protein.
Length = 439
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 192 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 245
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 246 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 305
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 306 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 360
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 361 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 406
>AF057569-1|AAC62492.1| 308|Homo sapiens upstream regulatory
element binding protein 1 protein.
Length = 308
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 61 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 114
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 115 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 174
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 175 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 229
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 230 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 275
>AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LASU1
protein.
Length = 3360
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 3113 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 3166
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 3167 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 3226
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 3227 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 3281
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 3282 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 3327
>AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.
Length = 3192
Score = 75.8 bits (178), Expect = 2e-13
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 6/226 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
+ R K+ILG+ +R+ D+ D Y+ L L+ + D +L DL FS E+
Sbjct: 2945 YFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLEN----DVSTL--GYDLTFSTEVQE 2998
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
+L P G + VT N +YV Q RM + K L A G +++P+ +
Sbjct: 2999 FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLIS 3058
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
T ++L LL++G+ I++ L S T ++ + +W W + +R
Sbjct: 3059 IFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ-----IQWFWRALRSFDQADRAK 3113
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRPADDA--HLPTANTC 710
+ F TG+ +P A+ EG + I D + LP+A+TC
Sbjct: 3114 FLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTC 3159
>D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein.
Length = 927
Score = 71.3 bits (167), Expect = 5e-12
Identities = 60/225 (26%), Positives = 98/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L +PI HD+ D Y SLR ++ + T LDL F ++
Sbjct: 682 FFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPT--------ELDLRFIIDEEL 733
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL GG E+ VT N +Y+ Q R + +K + A + G +++P+ ++
Sbjct: 734 FGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIK 793
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V +T + + + + +W W V M +R
Sbjct: 794 IFDENELELLMCGLGDVDVNDWREHTKYKNGYSANHQVI----QWFWKAVLMMDSEKRIR 849
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G S T+ LP A+TC
Sbjct: 850 LLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTC 894
>AY550969-1|AAT52215.1| 900|Homo sapiens cell proliferation-inducing
protein 53 protein.
Length = 900
Score = 71.3 bits (167), Expect = 5e-12
Identities = 60/225 (26%), Positives = 98/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L +PI HD+ D Y SLR ++ + T LDL F ++
Sbjct: 655 FFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPT--------ELDLRFIIDEEL 706
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL GG E+ VT N +Y+ Q R + +K + A + G +++P+ ++
Sbjct: 707 FGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIK 766
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V +T + + + + +W W V M +R
Sbjct: 767 IFDENELELLMCGLGDVDVNDWREHTKYKNGYSANHQVI----QWFWKAVLMMDSEKRIR 822
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G S T+ LP A+TC
Sbjct: 823 LLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTC 867
>AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligase
Smurf1-beta protein.
Length = 757
Score = 70.5 bits (165), Expect = 8e-12
Identities = 53/198 (26%), Positives = 88/198 (44%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+PI+ DL DP +++SL ++ + LD F +E
Sbjct: 516 KQLLGKPIQLSDLESVDPELHKSLVWIL-------ENDITPVLDHTFCVEHNAFGRILQH 568
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P GR + VT N +YVR Y R + E A++ G +++P+ L+ ++L
Sbjct: 569 ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 628
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+ I++ S T + + RW W V+ R L+ F TG
Sbjct: 629 ELIIGGLDKIDLNDWKSNTRLKHCVAD-----SNIVRWFWQAVETFDEERRARLLQFVTG 683
Query: 612 SPALPASEEGFQPMPSVT 665
S +P +GF+ + T
Sbjct: 684 STRVPL--QGFKALQGST 699
>AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMURF1
protein.
Length = 722
Score = 70.5 bits (165), Expect = 8e-12
Identities = 53/198 (26%), Positives = 88/198 (44%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+PI+ DL DP +++SL ++ + LD F +E
Sbjct: 481 KQLLGKPIQLSDLESVDPELHKSLVWIL-------ENDITPVLDHTFCVEHNAFGRILQH 533
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P GR + VT N +YVR Y R + E A++ G +++P+ L+ ++L
Sbjct: 534 ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 593
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+ I++ S T + + RW W V+ R L+ F TG
Sbjct: 594 ELIIGGLDKIDLNDWKSNTRLKHCVAD-----SNIVRWFWQAVETFDEERRARLLQFVTG 648
Query: 612 SPALPASEEGFQPMPSVT 665
S +P +GF+ + T
Sbjct: 649 STRVPL--QGFKALQGST 664
>AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2 protein.
Length = 712
Score = 70.5 bits (165), Expect = 8e-12
Identities = 53/198 (26%), Positives = 88/198 (44%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+PI+ DL DP +++SL ++ + LD F +E
Sbjct: 471 KQLLGKPIQLSDLESVDPELHKSLVWIL-------ENDITPVLDHTFCVEHNAFGRILQH 523
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P GR + VT N +YVR Y R + E A++ G +++P+ L+ ++L
Sbjct: 524 ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 583
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+ I++ S T + + RW W V+ R L+ F TG
Sbjct: 584 ELIIGGLDKIDLNDWKSNTRLKHCVAD-----SNIVRWFWQAVETFDEERRARLLQFVTG 638
Query: 612 SPALPASEEGFQPMPSVT 665
S +P +GF+ + T
Sbjct: 639 STRVPL--QGFKALQGST 654
>AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein.
Length = 859
Score = 70.5 bits (165), Expect = 8e-12
Identities = 53/198 (26%), Positives = 88/198 (44%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+PI+ DL DP +++SL ++ + LD F +E
Sbjct: 618 KQLLGKPIQLSDLESVDPELHKSLVWIL-------ENDITPVLDHTFCVEHNAFGRILQH 670
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P GR + VT N +YVR Y R + E A++ G +++P+ L+ ++L
Sbjct: 671 ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 730
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+ I++ S T + + RW W V+ R L+ F TG
Sbjct: 731 ELIIGGLDKIDLNDWKSNTRLKHCVAD-----SNIVRWFWQAVETFDEERRARLLQFVTG 785
Query: 612 SPALPASEEGFQPMPSVT 665
S +P +GF+ + T
Sbjct: 786 STRVPL--QGFKALQGST 801
>BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 510 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 562
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 563 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 622
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 677
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 678 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 716
>BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 510 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 562
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 563 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 622
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 677
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 678 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 716
>BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein.
Length = 288
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 50 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 102
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 103 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 162
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 163 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 217
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 218 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 256
>AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smurf2
protein.
Length = 748
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 510 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 562
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 563 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 622
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 677
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 678 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 716
>AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMURF2
protein.
Length = 748
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 510 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 562
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 563 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 622
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 677
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 678 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 716
>AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMURF2
protein.
Length = 748
Score = 68.1 bits (159), Expect = 4e-11
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +LG+ I D+ DP ++ SL ++ + TG LD F +E
Sbjct: 510 KQLLGKSITLDDMELVDPDLHNSLVWILENDITG-------VLDHTFCVEHNAYGEIIQH 562
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL P G+ + V N +YVR Y R L E A++ G +V+P+ L+ ++L
Sbjct: 563 ELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKEL 622
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L++ G+G I+V T + + + +W W V+ R L+ F TG
Sbjct: 623 ELIICGLGKIDVNDWKVNTRLKHCTPD-----SNIVKWFWKAVEFFDEERRARLLQFVTG 677
Query: 612 SPALPASEEGFQPMPSV------TIRPADDA--HLPTANTC 710
S +P +GF+ + TI D +LP A+TC
Sbjct: 678 SSRVPL--QGFKALQGAAGPRLFTIHQIDACTNNLPKAHTC 716
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 63.7 bits (148), Expect = 9e-10
Identities = 56/219 (25%), Positives = 104/219 (47%), Gaps = 4/219 (1%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V K + P+ DL D + ++L ++ ++G ++ F + + +
Sbjct: 4604 VWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEM-IPLDSFVGQSADGK 4662
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAE 425
V +IPGG + +T N +YV + ++R L ++ + A+R G+ ++P L LTA+
Sbjct: 4663 MVPIIPGGNSIPLTFSNRKEYVERAIEYR-LHEMDRQVAAVREGMSWIVPVPLLSLLTAK 4721
Query: 426 DLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L ++ G+ +I+V L + E EQ + + +W W +++ ++ ER + F
Sbjct: 4722 QLEQMVCGMPEISVEVLKKVVRYR-EVDEQHQLV----QWFWHTLEEFSNEERVLFMRFV 4776
Query: 606 TGSPALPAS----EEGFQPMPSVTIRPADDAHLPTANTC 710
+G LPA+ + FQ M RP D LPT+ TC
Sbjct: 4777 SGRSRLPANTADISQRFQIMK--VDRPYDS--LPTSQTC 4811
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 63.7 bits (148), Expect = 9e-10
Identities = 56/219 (25%), Positives = 104/219 (47%), Gaps = 4/219 (1%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V K + P+ DL D + ++L ++ ++G ++ F + + +
Sbjct: 394 VWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEM-IPLDSFVGQSADGK 452
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAE 425
V +IPGG + +T N +YV + ++R L ++ + A+R G+ ++P L LTA+
Sbjct: 453 MVPIIPGGNSIPLTFSNRKEYVERAIEYR-LHEMDRQVAAVREGMSWIVPVPLLSLLTAK 511
Query: 426 DLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L ++ G+ +I+V L + E EQ + + +W W +++ ++ ER + F
Sbjct: 512 QLEQMVCGMPEISVEVLKKVVRYR-EVDEQHQLV----QWFWHTLEEFSNEERVLFMRFV 566
Query: 606 TGSPALPAS----EEGFQPMPSVTIRPADDAHLPTANTC 710
+G LPA+ + FQ M RP D LPT+ TC
Sbjct: 567 SGRSRLPANTADISQRFQIMK--VDRPYDS--LPTSQTC 601
>DQ181796-1|ABA10330.1| 834|Homo sapiens NEDD4L variant protein.
Length = 834
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 589 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 640
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 641 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 700
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 701 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 756
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 757 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 801
>BC032597-1|AAH32597.1| 911|Homo sapiens NEDD4L protein protein.
Length = 911
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 666 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 717
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 718 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 777
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 778 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 833
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 834 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 878
>BC019345-1|AAH19345.1| 855|Homo sapiens Unknown (protein for
IMAGE:3604024) protein.
Length = 855
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 610 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 661
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 662 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 721
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 722 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 777
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 778 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 822
>BC000621-1|AAH00621.2| 855|Homo sapiens NEDD4L protein protein.
Length = 855
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 610 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 661
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 662 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 721
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 722 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 777
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 778 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 822
>AY312514-1|AAP75706.1| 975|Homo sapiens NEDD4.2 protein.
Length = 975
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 730 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 781
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 782 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 841
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 842 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 897
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 898 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 942
>AY112985-1|AAM76730.1| 947|Homo sapiens ubiquitin ligase NEDD4h
protein.
Length = 947
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 702 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 753
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 754 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 813
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 814 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 869
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 870 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 914
>AY112984-1|AAM76729.1| 967|Homo sapiens ubiquitin ligase NEDD4g
protein.
Length = 967
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 722 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 773
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 774 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 833
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 834 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 889
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 890 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 934
>AY112983-1|AAM76728.1| 854|Homo sapiens ubiquitin ligase NEDD4f
protein.
Length = 854
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 609 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 660
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 661 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 720
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 721 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 776
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 777 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 821
>AL137469-1|CAB70754.1| 820|Homo sapiens hypothetical protein
protein.
Length = 820
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 575 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 626
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 627 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 686
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 687 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 742
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 743 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 787
>AF385931-1|AAM46208.1| 854|Homo sapiens ubiquitin ligase NEDD4Lb
protein.
Length = 854
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 609 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 660
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 661 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 720
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 721 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 776
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 777 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 821
>AF210730-1|AAG43524.1| 854|Homo sapiens NEDD4La protein.
Length = 854
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 609 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 660
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 661 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 720
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 721 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 776
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 777 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 821
>AB071179-1|BAB69424.1| 955|Homo sapiens NEDD4-like ubiquitin ligase
3 protein.
Length = 955
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 710 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 761
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 762 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 821
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 822 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 877
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 878 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 922
>AB007899-1|BAA23711.1| 995|Homo sapiens KIAA0439 protein.
Length = 995
Score = 62.9 bits (146), Expect = 2e-09
Identities = 60/225 (26%), Positives = 97/225 (43%), Gaps = 5/225 (2%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +LG+ I +D+ D Y SL+ ++ + T LDL F ++
Sbjct: 750 FFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPT--------ELDLMFCIDEEN 801
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
V+L P G E+ VT N +Y+ Q R + +K + A G ++LP ++
Sbjct: 802 FGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIK 861
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
+L LL+ G+GD++V ++ + ++G P +W W V M +R
Sbjct: 862 IFDENELELLMCGLGDVDVNDWRQHSIY--KNGYCPNH--PVIQWFWKAVLLMDAEKRIR 917
Query: 591 LVYFWTGSPALP----ASEEGFQPMPSVTIRP-ADDAHLPTANTC 710
L+ F TG+ +P A G TI LP A+TC
Sbjct: 918 LLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTC 962
>BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein.
Length = 903
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 718
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 719 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 778
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 779 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 833
Query: 612 SPALP 626
+ LP
Sbjct: 834 TCRLP 838
>AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 718
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 719 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 778
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 779 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 833
Query: 612 SPALP 626
+ LP
Sbjct: 834 TCRLP 838
>AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 677
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 678 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 737
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 738 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 792
Query: 612 SPALP 626
+ LP
Sbjct: 793 TCRLP 797
>AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 718
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 719 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 778
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 779 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 833
Query: 612 SPALP 626
+ LP
Sbjct: 834 TCRLP 838
>AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 677
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 678 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 737
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 738 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 792
Query: 612 SPALP 626
+ LP
Sbjct: 793 TCRLP 797
>AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligase
ITCH protein.
Length = 862
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 677
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 678 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 737
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 738 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 792
Query: 612 SPALP 626
+ LP
Sbjct: 793 TCRLP 797
>AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting
protein 4 protein.
Length = 739
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 501 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 554
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 555 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 614
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 615 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 669
Query: 612 SPALP 626
+ LP
Sbjct: 670 TCRLP 674
>AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiquitin
protein ligase variant protein.
Length = 605
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 367 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 420
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 421 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 480
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 481 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 535
Query: 612 SPALP 626
+ LP
Sbjct: 536 TCRLP 540
>AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligase
Itch protein.
Length = 862
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/185 (24%), Positives = 87/185 (47%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K IL +P+ DL DP Y SL + + + + L++ FS++
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSL----IWVKENNIEE--CDLEMYFSVDKEILGEIKSH 677
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L P G + VT N +Y+R ++ R+ E+ +A G ++LP+ L+ A++L
Sbjct: 678 DLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKEL 737
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+LL G+ +I++ + + + R ++ W W V ++ + +R L+ F TG
Sbjct: 738 EVLLCGMQEIDLNDWQRHAIYRHYA-----RTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 792
Query: 612 SPALP 626
+ LP
Sbjct: 793 TCRLP 797
>X98033-1|CAA66656.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>X98032-1|CAA66655.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>X98031-1|CAA66654.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>X98021-1|CAA66653.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>U84404-1|AAB49301.1| 852|Homo sapiens E6-associated protein
E6-AP/ubiquitin-protein ligase protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>BC009271-1|AAH09271.1| 585|Homo sapiens UBE3A protein protein.
Length = 585
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 347 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 402
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 403 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 462
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 463 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 518
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 519 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 553
>AF273050-1|AAG34910.1| 852|Homo sapiens CTCL tumor antigen se37-2
protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>AF016708-1|AAB69154.1| 852|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 852
Score = 60.5 bits (140), Expect = 9e-09
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>BC002582-1|AAH02582.2| 872|Homo sapiens ubiquitin protein ligase E3A
(human papilloma virus E6-associated protein, Ange
protein.
Length = 872
Score = 60.1 bits (139), Expect = 1e-08
Identities = 54/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 634 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 689
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 690 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRP 749
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G ++ AL T ++ + F W IV T +++ + F
Sbjct: 750 EEIELLICGSRNLGFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 805
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 806 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 840
>AB194232-2|BAD69554.1| 852|Homo sapiens ubiquitin ligase E3A isoform
1 protein.
Length = 852
Score = 58.4 bits (135), Expect = 4e-08
Identities = 53/216 (24%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L ++ E + ++ +
Sbjct: 614 VYRKLMGKKGTFRDLGDSHPVLYQSLKDL-LEYEGNVEDDMMITFQIS---QTDLFGNPM 669
Query: 246 CVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-TA 422
+L G ++ +T N ++V YS + + S EK +A R G V E L+ L
Sbjct: 670 MYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNEPPLKYLFRP 729
Query: 423 EDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYF 602
E++ LL+ G +++ AL T ++ + F W IV T +++ + F
Sbjct: 730 EEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQF 785
Query: 603 WTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
TG+ P G M P D LPT++TC
Sbjct: 786 TTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 820
>L07557-1|AAA35542.1| 874|Homo sapiens oncogenic protein-associated
protein protein.
Length = 874
Score = 58.0 bits (134), Expect = 5e-08
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 2/217 (0%)
Frame = +3
Query: 66 VLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX 245
V + ++G+ F DL P++Y+SL+ L+ + + + F +
Sbjct: 636 VYRKLMGKKGLFVDLGDSHPVLYQSLKDLLEYVGNVEDDMM-----ITFQISQTNLFGNP 690
Query: 246 CV-ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGL-T 419
+ +L G ++ +T N ++V YS + + S EK +A R G V ES L+ L
Sbjct: 691 MMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFR 750
Query: 420 AEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVY 599
E++ LL+ G +++ AL T ++ + F W IV T +++ +
Sbjct: 751 PEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREF----WEIVHSFTDEQKRLFLQ 806
Query: 600 FWTGSPALPASEEGFQPMPSVTIRPADDAHLPTANTC 710
F TG+ P G M P D LPT++TC
Sbjct: 807 FTTGTDRAPVGGLGKLKMIIAKNGP-DTERLPTSHTC 842
>BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 1 protein.
Length = 1606
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/198 (26%), Positives = 86/198 (43%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L P DL + D ++SL Q + D D LDL F++
Sbjct: 1361 FFTRPFYKALLRLPCDLSDLEYLDEEFHQSL-QWMKDNNITD------ILDLTFTVNEEV 1413
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL GG +VT N +Y+ + + R+ + EA+ G +V+ +
Sbjct: 1414 FGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVS 1473
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I++ + T + G L RW WA V++ + +R
Sbjct: 1474 VFDARELELVIAGTAEIDLNDWRNNTEYR--GGYHDGHLVI--RWFWAAVERFNNEQRLR 1529
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1530 LLQFVTGTSSVP--YEGF 1545
>AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin ligase
1 protein.
Length = 1585
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/198 (26%), Positives = 86/198 (43%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L P DL + D ++SL Q + D D LDL F++
Sbjct: 1340 FFTRPFYKALLRLPCDLSDLEYLDEEFHQSL-QWMKDNNITD------ILDLTFTVNEEV 1392
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL GG +VT N +Y+ + + R+ + EA+ G +V+ +
Sbjct: 1393 FGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVS 1452
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I++ + T + G L RW WA V++ + +R
Sbjct: 1453 VFDARELELVIAGTAEIDLNDWRNNTEYR--GGYHDGHLVI--RWFWAAVERFNNEQRLR 1508
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1509 LLQFVTGTSSVP--YEGF 1524
>AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein.
Length = 1614
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/198 (26%), Positives = 86/198 (43%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L P DL + D ++SL Q + D D LDL F++
Sbjct: 1369 FFTRPFYKALLRLPCDLSDLEYLDEEFHQSL-QWMKDNNITD------ILDLTFTVNEEV 1421
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL GG +VT N +Y+ + + R+ + EA+ G +V+ +
Sbjct: 1422 FGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVS 1481
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I++ + T + G L RW WA V++ + +R
Sbjct: 1482 VFDARELELVIAGTAEIDLNDWRNNTEYR--GGYHDGHLVI--RWFWAAVERFNNEQRLR 1537
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1538 LLQFVTGTSSVP--YEGF 1553
>D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein.
Length = 1086
Score = 56.4 bits (130), Expect = 1e-07
Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 5/212 (2%)
Frame = +3
Query: 93 IRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCVELIPGGR 272
+ H LA DP VY++L L + + D + L LNF++ VEL GG+
Sbjct: 857 VDIHHLASLDPEVYKNL--LFLKSYEDDVEEL----GLNFTVVNNDLGEAQVVELKFGGK 910
Query: 273 ELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGV 452
++ VT+ N Y+ + +R+ + A R G+ +V+ L +++++L++G
Sbjct: 911 DIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGA 970
Query: 453 G-DINVAALVSYTSFN-DESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPALP 626
I++ L S+T+++ S + P + W +V+ T E++ L+ F T P
Sbjct: 971 QVPISLEDLKSFTNYSGGYSADHP-----VIKVFWRVVEGFTDEEKRKLLKFVTSCSRPP 1025
Query: 627 ASEEGFQPM-PSVTIR--PADDAHLPTANTCI 713
GF+ + P+ I +D LPTA+TC+
Sbjct: 1026 LL--GFKELYPAFCIHNGGSDLERLPTASTCM 1055
>BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/198 (25%), Positives = 88/198 (44%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L DL + D ++SL Q + D + D LDL F++
Sbjct: 1327 FFTRPFYKALLRILCDLSDLEYLDEEFHQSL-QWMKDNDIHD------ILDLTFTVNEEV 1379
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL PGG + VT N +Y+ + + R+ + E++ G +V+ +
Sbjct: 1380 FGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVS 1439
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I+++ + T + G + RW WA V++ + +R
Sbjct: 1440 VFDARELELVIAGTAEIDLSDWRNNTEY--RGGYHDNHIV--IRWFWAAVERFNNEQRLR 1495
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1496 LLQFVTGTSSIP--YEGF 1511
>BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/198 (25%), Positives = 88/198 (44%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L DL + D ++SL Q + D + D LDL F++
Sbjct: 1327 FFTRPFYKALLRILCDLSDLEYLDEEFHQSL-QWMKDNDIHD------ILDLTFTVNEEV 1379
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL PGG + VT N +Y+ + + R+ + E++ G +V+ +
Sbjct: 1380 FGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVS 1439
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I+++ + T + G + RW WA V++ + +R
Sbjct: 1440 VFDARELELVIAGTAEIDLSDWRNNTEY--RGGYHDNHIV--IRWFWAAVERFNNEQRLR 1495
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1496 LLQFVTGTSSIP--YEGF 1511
>AC004975-1|AAD51453.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 56.4 bits (130), Expect = 1e-07
Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 5/212 (2%)
Frame = +3
Query: 93 IRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCVELIPGGR 272
+ H LA DP VY++L L + + D + L LNF++ VEL GG+
Sbjct: 186 VDIHHLASLDPEVYKNL--LFLKSYEDDVEEL----GLNFTVVNNDLGEAQVVELKFGGK 239
Query: 273 ELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGV 452
++ VT+ N Y+ + +R+ + A R G+ +V+ L +++++L++G
Sbjct: 240 DIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGA 299
Query: 453 G-DINVAALVSYTSFN-DESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPALP 626
I++ L S+T+++ S + P + W +V+ T E++ L+ F T P
Sbjct: 300 QVPISLEDLKSFTNYSGGYSADHP-----VIKVFWRVVEGFTDEEKRKLLKFVTSCSRPP 354
Query: 627 ASEEGFQPM-PSVTIR--PADDAHLPTANTCI 713
GF+ + P+ I +D LPTA+TC+
Sbjct: 355 LL--GFKELYPAFCIHNGGSDLERLPTASTCM 384
>AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein.
Length = 1581
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/198 (25%), Positives = 88/198 (44%)
Frame = +3
Query: 51 FLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCX 230
F R K +L DL + D ++SL Q + D + D LDL F++
Sbjct: 1336 FFTRPFYKALLRILCDLSDLEYLDEEFHQSL-QWMKDNDIHD------ILDLTFTVNEEV 1388
Query: 231 XXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALE 410
EL PGG + VT N +Y+ + + R+ + E++ G +V+ +
Sbjct: 1389 FGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVS 1448
Query: 411 GLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQD 590
A +L L++ G +I+++ + T + G + RW WA V++ + +R
Sbjct: 1449 VFDARELELVIAGTAEIDLSDWRNNTEY--RGGYHDNHIV--IRWFWAAVERFNNEQRLR 1504
Query: 591 LVYFWTGSPALPASEEGF 644
L+ F TG+ ++P EGF
Sbjct: 1505 LLQFVTGTSSIP--YEGF 1520
>BC130470-1|AAI30471.1| 577|Homo sapiens HECT domain containing 3
protein.
Length = 577
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 396 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 454
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 455 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 509
Query: 609 GSPALPA 629
G LPA
Sbjct: 510 GRSRLPA 516
>BC126352-1|AAI26353.1| 577|Homo sapiens HECT domain containing 3
protein.
Length = 577
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 396 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 454
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 455 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 509
Query: 609 GSPALPA 629
G LPA
Sbjct: 510 GRSRLPA 516
>BC063686-1|AAH63686.1| 347|Homo sapiens HECTD1 protein protein.
Length = 347
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 125 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 183
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 184 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 243
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 244 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 299
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 300 VRKVDATDASYPSVNTCV 317
>BC019105-1|AAH19105.1| 210|Homo sapiens HECTD3 protein protein.
Length = 210
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 29 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 87
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 88 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 142
Query: 609 GSPALPA 629
G LPA
Sbjct: 143 GRSRLPA 149
>BC011658-1|AAH11658.2| 520|Homo sapiens HECTD1 protein protein.
Length = 520
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 298 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 356
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 357 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 416
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 417 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 472
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 473 VRKVDATDASYPSVNTCV 490
>AY739714-1|AAW65983.1| 1224|Homo sapiens HECTD1 protein.
Length = 1224
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 1002 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 1060
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 1061 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 1120
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 1121 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 1176
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 1177 VRKVDATDASYPSVNTCV 1194
>AY254380-1|AAP13073.1| 2612|Homo sapiens E3 ligase for inhibin
receptor protein.
Length = 2612
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 2390 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 2448
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 2449 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 2508
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 2509 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 2564
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 2565 VRKVDATDASYPSVNTCV 2582
>AL359473-2|CAI16438.1| 861|Homo sapiens HECT domain containing 3
protein.
Length = 861
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 680 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 738
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 739 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 793
Query: 609 GSPALPA 629
G LPA
Sbjct: 794 GRSRLPA 800
>AL359473-1|CAI16437.1| 471|Homo sapiens HECT domain containing 3
protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 290 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 348
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 349 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 403
Query: 609 GSPALPA 629
G LPA
Sbjct: 404 GRSRLPA 410
>AL110222-1|CAB53681.1| 959|Homo sapiens hypothetical protein
protein.
Length = 959
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 737 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 795
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 796 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 855
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 856 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 911
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 912 VRKVDATDASYPSVNTCV 929
>AK024809-1|BAB15015.1| 210|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21156 fis, clone CAS09878. ).
Length = 210
Score = 53.2 bits (122), Expect = 1e-06
Identities = 37/127 (29%), Positives = 65/127 (51%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
VELIPGG + V + +++ + R+ S+E+ + AM+ G+L V+P++ L+ LT ++
Sbjct: 29 VELIPGGAGIVVGYGDRSRFIQLVQKARLEESKEQ-VAAMQAGLLKVVPQAVLDLLTWQE 87
Query: 429 LRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWT 608
L + G ++ V AL T F D ++ W ++ T+ +R + F T
Sbjct: 88 LEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-----VQYFWEALNNFTNEDRSRFLRFVT 142
Query: 609 GSPALPA 629
G LPA
Sbjct: 143 GRSRLPA 149
>AB032957-1|BAA86445.2| 2168|Homo sapiens KIAA1131 protein protein.
Length = 2168
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Frame = +3
Query: 141 LRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXX---CVELIPGGRELEVTAHNVYDYV 311
L++LV+ +G L + DL + + C V+L P G + +T N +YV
Sbjct: 1946 LQELVLKNPSGSGPPL-SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYV 2004
Query: 312 RKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLRLLLNGVGDINVAA--LVSY 485
M +K +EA R G V P L + E+++++L G + AA +++Y
Sbjct: 2005 DLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINY 2064
Query: 486 TSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGSPAL-PASEEGFQPMPSV 662
T RF R ++ M+ ER+ + F TG L P P +V
Sbjct: 2065 TEPKLGYTRDSPGFLRFVR----VLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTV 2120
Query: 663 TIR-PADDAHLPTANTCI 713
+ A DA P+ NTC+
Sbjct: 2121 VRKVDATDASYPSVNTCV 2138
>U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein.
Length = 870
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/185 (24%), Positives = 80/185 (43%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL DP Y S +V + + + L+L F +M
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNS----IVWIKENNLEE--CGLELYFIQDMEILGKVTTH 685
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL GG + VT N +Y+ + R E+ +A G +V P L ++L
Sbjct: 686 ELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKEL 745
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L+L G+ +I+++ T + + + ++ +W W +V +M + +R L+ F TG
Sbjct: 746 ELMLCGMQEIDMSDWQKSTIYRHYT-----KNSKQIQWFWQVVKEMDNEKRIRLLQFVTG 800
Query: 612 SPALP 626
+ LP
Sbjct: 801 TCRLP 805
>BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein.
Length = 870
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/185 (24%), Positives = 80/185 (43%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL DP Y S +V + + + L+L F +M
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNS----IVWIKENNLEE--CGLELYFIQDMEILGKVTTH 685
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL GG + VT N +Y+ + R E+ +A G +V P L ++L
Sbjct: 686 ELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKEL 745
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L+L G+ +I+++ T + + + ++ +W W +V +M + +R L+ F TG
Sbjct: 746 ELMLCGMQEIDMSDWQKSTIYRHYT-----KNSKQIQWFWQVVKEMDNEKRIRLLQFVTG 800
Query: 612 SPALP 626
+ LP
Sbjct: 801 TCRLP 805
>BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3
ubiquitin protein ligase 2 protein.
Length = 870
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/185 (24%), Positives = 80/185 (43%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL DP Y S +V + + + L+L F +M
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNS----IVWIKENNLEE--CGLELYFIQDMEILGKVTTH 685
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL GG + VT N +Y+ + R E+ +A G +V P L ++L
Sbjct: 686 ELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKEL 745
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
L+L G+ +I+++ T + + + ++ +W W +V +M + +R L+ F TG
Sbjct: 746 ELMLCGMQEIDMSDWQKSTIYRHYT-----KNSKQIQWFWQVVKEMDNEKRIRLLQFVTG 800
Query: 612 SPALP 626
+ LP
Sbjct: 801 TCRLP 805
>L40383-1|AAC41731.1| 174|Homo sapiens thyroid receptor interactor
protein.
Length = 174
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
+EL GG+++ VT HN+ +Y+R + + ++ R G V P S L+ E+
Sbjct: 2 IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEE 61
Query: 429 L-RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L +LL D A + D R +F L+ I+ + +++ + F
Sbjct: 62 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKF---LFEILSSFDNEQQRLFLQFV 118
Query: 606 TGSPALPASEEGFQPM-PSVTI-------RPADDAHLPTANTCI 713
TGSP LP GF+ + P +TI D LP+ TC+
Sbjct: 119 TGSPRLPVG--GFRSLNPPLTIVRKTFESTENPDDFLPSVMTCV 160
>D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein.
Length = 2005
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
+EL GG+++ VT HN+ +Y+R + + ++ R G V P S L+ E+
Sbjct: 1815 IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEE 1874
Query: 429 L-RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L +LL D A + D R +F L+ I+ + +++ + F
Sbjct: 1875 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKF---LFEILSSFDNEQQRLFLQFV 1931
Query: 606 TGSPALPASEEGFQPM-PSVTI-------RPADDAHLPTANTCI 713
TGSP LP GF+ + P +TI D LP+ TC+
Sbjct: 1932 TGSPRLPVG--GFRSLNPPLTIVRKTFESTENPDDFLPSVMTCV 1973
>BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein.
Length = 2040
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
+EL GG+++ VT HN+ +Y+R + + ++ R G V P S L+ E+
Sbjct: 1850 IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEE 1909
Query: 429 L-RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L +LL D A + D R +F L+ I+ + +++ + F
Sbjct: 1910 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKF---LFEILSSFDNEQQRLFLQFV 1966
Query: 606 TGSPALPASEEGFQPM-PSVTI-------RPADDAHLPTANTCI 713
TGSP LP GF+ + P +TI D LP+ TC+
Sbjct: 1967 TGSPRLPVG--GFRSLNPPLTIVRKTFESTENPDDFLPSVMTCV 2008
>BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein.
Length = 1722
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
+EL GG+++ VT HN+ +Y+R + + ++ R G V P S L+ E+
Sbjct: 1532 IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEE 1591
Query: 429 L-RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L +LL D A + D R +F L+ I+ + +++ + F
Sbjct: 1592 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKF---LFEILSSFDNEQQRLFLQFV 1648
Query: 606 TGSPALPASEEGFQPM-PSVTI-------RPADDAHLPTANTCI 713
TGSP LP GF+ + P +TI D LP+ TC+
Sbjct: 1649 TGSPRLPVG--GFRSLNPPLTIVRKTFESTENPDDFLPSVMTCV 1690
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P + +SL++++ DA + + AL + FS+ V
Sbjct: 785 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDA----ADDIGDALCIRFSIHWDQND----V 836
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+LIP G + V N DYV KY + +S + E + G V + L E+L
Sbjct: 837 DLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEEL 896
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ G D + + + E G Q + W K+T E++ ++F TG
Sbjct: 897 MTAIIGNTDYDWKQFEQNSKY--EQGYQKSHPT--IQLFWKAFHKLTLDEKKKFLFFLTG 952
Query: 612 SPALPASEEGFQPMPSVTIRPA--DDAHLPTANTC 710
L A G Q M V P + PT+ TC
Sbjct: 953 RDRLHA--RGIQKMEIVFRCPETFSERDHPTSITC 985
>BC035775-1|AAH35775.2| 396|Homo sapiens HERC6 protein protein.
Length = 396
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P + +SL++++ DA + + AL + FS+ V
Sbjct: 159 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDA----ADDIGDALCIRFSIHWDQND----V 210
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+LIP G + V N DYV KY + +S + E + G V + L E+L
Sbjct: 211 DLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEEL 270
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ G D + + + E G Q + W K+T E++ ++F TG
Sbjct: 271 MTAIIGNTDYDWKQFEQNSKY--EQGYQKSHPT--IQLFWKAFHKLTLDEKKKFLFFLTG 326
Query: 612 SPALPASEEGFQPMPSVTIRPA--DDAHLPTANTC 710
L A G Q M V P + PT+ TC
Sbjct: 327 RDRLHA--RGIQKMEIVFRCPETFSERDHPTSITC 359
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P + +SL++++ DA + + AL + FS+ V
Sbjct: 749 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDA----ADDIGDALCIRFSIHWDQND----V 800
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+LIP G + V N DYV KY + +S + E + G V + L E+L
Sbjct: 801 DLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEEL 860
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ G D + + + E G Q + W K+T E++ ++F TG
Sbjct: 861 MTAIIGNTDYDWKQFEQNSKY--EQGYQKSHPT--IQLFWKAFHKLTLDEKKKFLFFLTG 916
Query: 612 SPALPASEEGFQPMPSVTIRPA--DDAHLPTANTC 710
L A G Q M V P + PT+ TC
Sbjct: 917 RDRLHA--RGIQKMEIVFRCPETFSERDHPTSITC 949
>AK000644-1|BAA91303.1| 379|Homo sapiens protein ( Homo sapiens
cDNA FLJ20637 fis, clone KAT03212. ).
Length = 379
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P + +SL++++ DA + + AL + FS+ V
Sbjct: 142 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDA----ADDIGDALCIRFSIHWDQND----V 193
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+LIP G + V N DYV KY + +S + E + G V + L E+L
Sbjct: 194 DLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEEL 253
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ G D + + + E G Q + W K+T E++ ++F TG
Sbjct: 254 MTAIIGNTDYDWKQFEQNSKY--EQGYQKSHPT--IQLFWKAFHKLTLDEKKKFLFFLTG 309
Query: 612 SPALPASEEGFQPMPSVTIRPA--DDAHLPTANTC 710
L A G Q M V P + PT+ TC
Sbjct: 310 RDRLHA--RGIQKMEIVFRCPETFSERDHPTSITC 342
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P + +SL++++ DA + + AL + FS+ V
Sbjct: 785 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDA----ADDIGDALCIRFSIHWDQND----V 836
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+LIP G + V N DYV KY + +S + E + G V + L E+L
Sbjct: 837 DLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEEL 896
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ G D + + + E G Q + W K+T E++ ++F TG
Sbjct: 897 MTAIIGNTDYDWKQFEQNSKY--EQGYQKSHPT--IQLFWKAFHKLTLDEKKKFLFFLTG 952
Query: 612 SPALPASEEGFQPMPSVTIRPA--DDAHLPTANTC 710
L A G Q M V P + PT+ TC
Sbjct: 953 RDRLHA--RGIQKMEIVFRCPETFSERDHPTSITC 985
>AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein.
Length = 1299
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Frame = +3
Query: 249 VELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAED 428
+EL GG+++ VT HN+ +Y+R + + ++ R G V P S L+ E+
Sbjct: 1109 IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEE 1168
Query: 429 L-RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFW 605
L +LL D A + D R +F L+ I+ + +++ + F
Sbjct: 1169 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKF---LFEILSSFDNEQQRLFLQFV 1225
Query: 606 TGSPALPASEEGFQPM-PSVTI-------RPADDAHLPTANTCI 713
TGSP LP GF+ + P +TI D LP+ TC+
Sbjct: 1226 TGSPRLPVG--GFRSLNPPLTIVRKTFESTENPDDFLPSVMTCV 1267
>BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3
ubiquitin protein ligase 1 protein.
Length = 922
Score = 46.0 bits (104), Expect = 2e-04
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 5/218 (2%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + + DL D Y SL + D+ L++ FS++M
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSLIWI------RDNNIEECGLEMYFSVDMEILGKVTSH 737
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L GG + VT N +Y+ ++ R ++ +A G +V+P L+ ++L
Sbjct: 738 DLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKEL 797
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
++L G+ ++++A T + + + + W W V + + R L+ F TG
Sbjct: 798 EVMLCGMQEVDLADWQRNTVYRHYTRNSKQII-----WFWQFVKETDNEVRMRLLQFVTG 852
Query: 612 SPALP----ASEEGFQ-PMPSVTIRPADDAHLPTANTC 710
+ LP A G P + D LP ++TC
Sbjct: 853 TCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTC 890
>BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein.
Length = 300
Score = 46.0 bits (104), Expect = 2e-04
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 5/218 (2%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + + DL D Y SL + D+ L++ FS++M
Sbjct: 62 KRMLSKKLTIKDLESIDTEFYNSLIWI------RDNNIEECGLEMYFSVDMEILGKVTSH 115
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L GG + VT N +Y+ ++ R ++ +A G +V+P L+ ++L
Sbjct: 116 DLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKEL 175
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
++L G+ ++++A T + + + + W W V + + R L+ F TG
Sbjct: 176 EVMLCGMQEVDLADWQRNTVYRHYTRNSKQII-----WFWQFVKETDNEVRMRLLQFVTG 230
Query: 612 SPALP----ASEEGFQ-PMPSVTIRPADDAHLPTANTC 710
+ LP A G P + D LP ++TC
Sbjct: 231 TCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTC 268
>AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiquitin
ligase 1 protein.
Length = 922
Score = 46.0 bits (104), Expect = 2e-04
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 5/218 (2%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + + DL D Y SL + D+ L++ FS++M
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSLIWI------RDNNIEECGLEMYFSVDMEILGKVTSH 737
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L GG + VT N +Y+ ++ R ++ +A G +V+P L+ ++L
Sbjct: 738 DLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKEL 797
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
++L G+ ++++A T + + + + W W V + + R L+ F TG
Sbjct: 798 EVMLCGMQEVDLADWQRNTVYRHYTRNSKQII-----WFWQFVKETDNEVRMRLLQFVTG 852
Query: 612 SPALP----ASEEGFQ-PMPSVTIRPADDAHLPTANTC 710
+ LP A G P + D LP ++TC
Sbjct: 853 TCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTC 890
>AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing protein
1 protein.
Length = 922
Score = 46.0 bits (104), Expect = 2e-04
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 5/218 (2%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + + DL D Y SL + D+ L++ FS++M
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSLIWI------RDNNIEECGLEMYFSVDMEILGKVTSH 737
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L GG + VT N +Y+ ++ R ++ +A G +V+P L+ ++L
Sbjct: 738 DLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKEL 797
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
++L G+ ++++A T + + + + W W V + + R L+ F TG
Sbjct: 798 EVMLCGMQEVDLADWQRNTVYRHYTRNSKQII-----WFWQFVKETDNEVRMRLLQFVTG 852
Query: 612 SPALP----ASEEGFQ-PMPSVTIRPADDAHLPTANTC 710
+ LP A G P + D LP ++TC
Sbjct: 853 TCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTC 890
>U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein.
Length = 684
Score = 44.8 bits (101), Expect = 5e-04
Identities = 41/185 (22%), Positives = 79/185 (42%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + + DL D Y SL + D+ L++ FS++M
Sbjct: 495 KRMLSKKLTIKDLESIDTEFYNSLIWI------RDNNIEECGLEMYFSVDMEILGKVTSH 548
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
+L GG + VT N +Y+ ++ R ++ +A G +V+P L+ ++L
Sbjct: 549 DLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKEL 608
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
++L G+ ++++A T + + + + W W V + + R L+ F TG
Sbjct: 609 EVMLCGMQEVDLADWQRNTVYRHYTRNSKQII-----WFWQFVKETDNEVRMRLLQFVTG 663
Query: 612 SPALP 626
+ LP
Sbjct: 664 TCRLP 668
>BC040187-1|AAH40187.1| 776|Homo sapiens HECT domain containing 2
protein.
Length = 776
Score = 44.4 bits (100), Expect = 6e-04
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
L PGG ++ VT N +YV+ Y+ + S K A G V +AL L E++
Sbjct: 599 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVE 658
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
+L+ G D+++ AL T ++ G L ++ W +V ++ L++F TGS
Sbjct: 659 ILVCGSPDLDMHALQRSTQYD---GYAKTDLT--IKYFWDVVLGFPLDLQKKLLHFTTGS 713
Query: 615 PALPASEEGFQPMP-SVTIRPADDAHLPTANTC 710
+P G + ++ LP A+TC
Sbjct: 714 DRVPVG--GMADLNFKISKNETSTNCLPVAHTC 744
>AL834183-1|CAD38880.1| 523|Homo sapiens hypothetical protein
protein.
Length = 523
Score = 44.4 bits (100), Expect = 6e-04
Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 5/226 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
L L V K + G + DL+ D L + + T + F A+ L F++
Sbjct: 241 LNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEE---FEAMSLPFTVPSA 297
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
++L + +T N +YVR +R+ E+ + A+R G+ V+P L
Sbjct: 298 SGQD---IQL--SSKHTHITLDNRAEYVRLAINYRLHEFDEQ-VAAVREGMARVVPVPLL 351
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
T +L ++ G DI + L S ++ G +P A +W W +++ ++ ER
Sbjct: 352 SLFTGYELETMVCGSPDIPLHLLKSVATYK---GIEPS--ASLIQWFWEVMESFSNTERS 406
Query: 588 DLVYFWTGSPALPASEEGFQPMPSVTIRPAD-----DAHLPTANTC 710
+ F G LP + F+ V I+ D D LP + TC
Sbjct: 407 LFLRFVWGRTRLPRTIADFRGRDFV-IQVLDKYNPPDHFLPESYTC 451
>AL713675-1|CAD28480.1| 238|Homo sapiens hypothetical protein
protein.
Length = 238
Score = 44.4 bits (100), Expect = 6e-04
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
L PGG ++ VT N +YV+ Y+ + S K A G V +AL L E++
Sbjct: 61 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVE 120
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
+L+ G D+++ AL T ++ G L ++ W +V ++ L++F TGS
Sbjct: 121 ILVCGSPDLDMHALQRSTQYD---GYAKTDLT--IKYFWDVVLGFPLDLQKKLLHFTTGS 175
Query: 615 PALPASEEGFQPMP-SVTIRPADDAHLPTANTC 710
+P G + ++ LP A+TC
Sbjct: 176 DRVPVG--GMADLNFKISKNETSTNCLPVAHTC 206
>AL161798-4|CAH70053.1| 776|Homo sapiens HECT domain containing 2
protein.
Length = 776
Score = 44.4 bits (100), Expect = 6e-04
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
L PGG ++ VT N +YV+ Y+ + S K A G V +AL L E++
Sbjct: 599 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVE 658
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
+L+ G D+++ AL T ++ G L ++ W +V ++ L++F TGS
Sbjct: 659 ILVCGSPDLDMHALQRSTQYD---GYAKTDLT--IKYFWDVVLGFPLDLQKKLLHFTTGS 713
Query: 615 PALPASEEGFQPMP-SVTIRPADDAHLPTANTC 710
+P G + ++ LP A+TC
Sbjct: 714 DRVPVG--GMADLNFKISKNETSTNCLPVAHTC 744
>AL161798-1|CAH70050.1| 426|Homo sapiens HECT domain containing 2
protein.
Length = 426
Score = 44.4 bits (100), Expect = 6e-04
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
L PGG ++ VT N +YV+ Y+ + S K A G V +AL L E++
Sbjct: 249 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVE 308
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
+L+ G D+++ AL T ++ G L ++ W +V ++ L++F TGS
Sbjct: 309 ILVCGSPDLDMHALQRSTQYD---GYAKTDLT--IKYFWDVVLGFPLDLQKKLLHFTTGS 363
Query: 615 PALPASEEGFQPMP-SVTIRPADDAHLPTANTC 710
+P G + ++ LP A+TC
Sbjct: 364 DRVPVG--GMADLNFKISKNETSTNCLPVAHTC 394
>AF225409-1|AAO27484.1| 306|Homo sapiens HERC2 protein.
Length = 306
Score = 44.4 bits (100), Expect = 6e-04
Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 5/226 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
L L V K + G + DL+ D L + + T + F A+ L F++
Sbjct: 24 LNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEE---FEAMSLPFTVPSA 80
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
++L + +T N +YVR +R+ E+ + A+R G+ V+P L
Sbjct: 81 SGQD---IQL--SSKHTHITLDNRAEYVRLAINYRLHEFDEQ-VAAVREGMARVVPVPLL 134
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
T +L ++ G DI + L S ++ G +P A +W W +++ ++ ER
Sbjct: 135 SLFTGYELETMVCGSPDIPLHLLKSVATYK---GIEPS--ASLIQWFWEVMESFSNTERS 189
Query: 588 DLVYFWTGSPALPASEEGFQPMPSVTIRPAD-----DAHLPTANTC 710
+ F G LP + F+ V I+ D D LP + TC
Sbjct: 190 LFLRFVWGRTRLPRTIADFRGRDFV-IQVLDKYNPPDHFLPESYTC 234
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 44.4 bits (100), Expect = 6e-04
Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 5/226 (2%)
Frame = +3
Query: 48 LFLNRHVLKYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMC 227
L L V K + G + DL+ D L + + T + F A+ L F++
Sbjct: 4552 LNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEE---FEAMSLPFTVPSA 4608
Query: 228 XXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESAL 407
++L + +T N +YVR +R+ E+ + A+R G+ V+P L
Sbjct: 4609 SGQD---IQL--SSKHTHITLDNRAEYVRLAINYRLHEFDEQ-VAAVREGMARVVPVPLL 4662
Query: 408 EGLTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQ 587
T +L ++ G DI + L S ++ G +P A +W W +++ ++ ER
Sbjct: 4663 SLFTGYELETMVCGSPDIPLHLLKSVATYK---GIEPS--ASLIQWFWEVMESFSNTERS 4717
Query: 588 DLVYFWTGSPALPASEEGFQPMPSVTIRPAD-----DAHLPTANTC 710
+ F G LP + F+ V I+ D D LP + TC
Sbjct: 4718 LFLRFVWGRTRLPRTIADFRGRDFV-IQVLDKYNPPDHFLPESYTC 4762
>BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligase E3B
protein.
Length = 1068
Score = 37.1 bits (82), Expect = 0.093
Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 2/145 (1%)
Frame = +3
Query: 198 LDLNFSLEMCXXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVG 377
L L S + C ELIPGG+ + VT N Y+ + RM + A+ G
Sbjct: 843 LGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISG 902
Query: 378 VLDVLPESALEGLTAEDLRLLLNG-VGDINVAALVSYTSFNDESGEQPERLARFKRWLWA 554
++ + + +L+ L++G +I++ L +T + G R WLW
Sbjct: 903 FRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVY--YGGFHGSH--RVIIWLWD 958
Query: 555 IV-DKMTHLERQDLVYFWTGSPALP 626
I+ T ER + F T P
Sbjct: 959 ILASDFTPDERAMFLKFVTSCSRPP 983
>BC032301-1|AAH32301.1| 1026|Homo sapiens UBE3B protein protein.
Length = 1026
Score = 37.1 bits (82), Expect = 0.093
Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 2/145 (1%)
Frame = +3
Query: 198 LDLNFSLEMCXXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVG 377
L L S + C ELIPGG+ + VT N Y+ + RM + A+ G
Sbjct: 843 LGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISG 902
Query: 378 VLDVLPESALEGLTAEDLRLLLNG-VGDINVAALVSYTSFNDESGEQPERLARFKRWLWA 554
++ + + +L+ L++G +I++ L +T + G R WLW
Sbjct: 903 FRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVY--YGGFHGSH--RVIIWLWD 958
Query: 555 IV-DKMTHLERQDLVYFWTGSPALP 626
I+ T ER + F T P
Sbjct: 959 ILASDFTPDERAMFLKFVTSCSRPP 983
>AK092426-1|BAC03887.1| 258|Homo sapiens protein ( Homo sapiens
cDNA FLJ35107 fis, clone PLACE6006871, moderately
similar to SUPPRESSOR PROTEIN SRP40. ).
Length = 258
Score = 37.1 bits (82), Expect = 0.093
Identities = 45/174 (25%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Frame = -2
Query: 595 TKSCLSKCVILSTI---AHSQRLKRASRSGCSPLSSLKLV*ETRAATFISPTPFSSRRKS 425
++S LS ++ S+I + S +S S SP SS + +++ SP+ SS S
Sbjct: 42 SRSILSSSILSSSIPSSSSSSSSPSSSHSSSSPSSSHSSSSPSSSSSTSSPSSSSSSSSS 101
Query: 424 SAVKPSSADSGNTSRTPTRIASRAFS*EINILCWEYLRT*S*TLCAVTSSSRPPGMSSTQ 245
S+ S++ S ++S +P+ +S + S + + S + + +SSS P SS+
Sbjct: 102 SSPSSSNSSSSSSSSSPSSSSSSSSSSPSS-------SSSSPSSSSSSSSSSPSSSSSSP 154
Query: 244 PPPSSSHISKLKLRSRAAKSD*ESPVSASTTSCRRLSYTIGSKNAKSWNRIGRP 83
SSS S S ++ S S S+S +S S + S ++ R P
Sbjct: 155 SSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSSSSPSSSSSSPSPRSSSP 208
Score = 31.9 bits (69), Expect = 3.5
Identities = 40/164 (24%), Positives = 63/164 (38%)
Frame = -2
Query: 640 PSSEAGKAGDPVQKYTKSCLSKCVILSTIAHSQRLKRASRSGCSPLSSLKLV*ETRAATF 461
PSS + + + S S + + S S S SP SS + +++
Sbjct: 92 PSSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSPSSSS 151
Query: 460 ISPTPFSSRRKSSAVKPSSADSGNTSRTPTRIASRAFS*EINILCWEYLRT*S*TLCAVT 281
SP+ SS SS+ PSS+ ++ +P+ S S + + +
Sbjct: 152 SSPSSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSS----------------SSSSPS 195
Query: 280 SSSRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVSASTTS 149
SSS P S+ P SSS S S ++ S S S+S S
Sbjct: 196 SSSSSPSPRSSSPSSSSSSTSSPSTSSPSSSSPSSSSPSSSCPS 239
>AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein.
Length = 1068
Score = 37.1 bits (82), Expect = 0.093
Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 2/145 (1%)
Frame = +3
Query: 198 LDLNFSLEMCXXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVG 377
L L S + C ELIPGG+ + VT N Y+ + RM + A+ G
Sbjct: 843 LGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISG 902
Query: 378 VLDVLPESALEGLTAEDLRLLLNG-VGDINVAALVSYTSFNDESGEQPERLARFKRWLWA 554
++ + + +L+ L++G +I++ L +T + G R WLW
Sbjct: 903 FRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVY--YGGFHGSH--RVIIWLWD 958
Query: 555 IV-DKMTHLERQDLVYFWTGSPALP 626
I+ T ER + F T P
Sbjct: 959 ILASDFTPDERAMFLKFVTSCSRPP 983
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 814 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 869
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 870 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 929
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 930 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 985
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 986 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 1017
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 36.7 bits (81), Expect = 0.12
Identities = 29/123 (23%), Positives = 47/123 (38%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
LIP G + V N DYV KY + S + E R G + E ++ E+L+
Sbjct: 847 LIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELK 906
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
++ G D + + + F W K+T E++ + F TG+
Sbjct: 907 DVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMF----WKAFHKLTLEEKKKFLVFLTGT 962
Query: 615 PAL 623
L
Sbjct: 963 DRL 965
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 822 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 877
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 878 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 937
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 938 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 993
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 994 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 1025
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 814 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 869
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 870 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 929
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 930 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 985
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 986 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 1017
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 672 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 727
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 728 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 787
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 788 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 843
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 844 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 875
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 814 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 869
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 870 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 929
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 930 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 985
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 986 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 1017
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 672 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 727
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 728 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 787
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 788 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 843
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 844 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 875
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 36.7 bits (81), Expect = 0.12
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 1/214 (0%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL P V S++QL+ D D + F LNF++ +
Sbjct: 718 KKLLKKKPSLDDLKELMPDVGRSMQQLL-DYPEDDIEETFC---LNFTITVENFGATEVK 773
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL+ G + V N ++V Y + S +A G V L +L
Sbjct: 774 ELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNEL 833
Query: 432 RLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTG 611
+ ++ G + + L T + E + + F W + ++ +++ + F TG
Sbjct: 834 QAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIF----WEVFHELPLEKKKQFLLFLTG 889
Query: 612 SPALPASEEGFQPMPSV-TIRPADDAHLPTANTC 710
S +P G + + V + +LP ++TC
Sbjct: 890 SDRIPIL--GMKSLKLVIQSTGGGEEYLPVSHTC 921
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 36.7 bits (81), Expect = 0.12
Identities = 29/123 (23%), Positives = 47/123 (38%)
Frame = +3
Query: 255 LIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDLR 434
LIP G + V N DYV KY + S + E R G + E ++ E+L+
Sbjct: 847 LIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELK 906
Query: 435 LLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDLVYFWTGS 614
++ G D + + + F W K+T E++ + F TG+
Sbjct: 907 DVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMF----WKAFHKLTLEEKKKFLVFLTGT 962
Query: 615 PAL 623
L
Sbjct: 963 DRL 965
>BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein
protein.
Length = 1068
Score = 36.3 bits (80), Expect = 0.16
Identities = 36/146 (24%), Positives = 58/146 (39%), Gaps = 3/146 (2%)
Frame = +3
Query: 198 LDLNFSLEMCXXXXXXCVELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVG 377
L L S + C ELIPGG+ + VT N Y+ + RM + A+ G
Sbjct: 843 LGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISG 902
Query: 378 VLDVLPESALEGLTAEDLRLLLNG-VGDINVAALVSYT-SFNDESGEQPERLARFKRWLW 551
++ + + +L+ L++G +I++ L +T + G R WLW
Sbjct: 903 FRSIVKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVHYGGFHGSH-----RVIIWLW 957
Query: 552 AIV-DKMTHLERQDLVYFWTGSPALP 626
I+ T ER + F T P
Sbjct: 958 DILASDFTPDERAMFLKFVTSCSRPP 983
>AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens
cDNA FLJ44359 fis, clone TRACH3007479, highly similar
to Homo sapiens Nedd-4-like ubiquitin-protein ligase
(WWP2). ).
Length = 343
Score = 35.9 bits (79), Expect = 0.21
Identities = 34/133 (25%), Positives = 55/133 (41%)
Frame = +3
Query: 72 KYILGRPIRFHDLAFFDPIVYESLRQLVVDAETGDSQSLFAALDLNFSLEMCXXXXXXCV 251
K +L + DL DP Y S +V + + + L+L F +M
Sbjct: 193 KRMLNKRPTLKDLESIDPEFYNS----IVWIKENNLEE--CGLELYFIQDMEILGKVTTH 246
Query: 252 ELIPGGRELEVTAHNVYDYVRKYSQHRMLISQEKALEAMRVGVLDVLPESALEGLTAEDL 431
EL GG + VT N +Y+ + R E+ +A G +V P L ++L
Sbjct: 247 ELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKEL 306
Query: 432 RLLLNGVGDINVA 470
L+L G+ +I+ A
Sbjct: 307 ELMLCGMQEIDRA 319
>AF010403-1|AAC51734.1| 5262|Homo sapiens ALR protein.
Length = 5262
Score = 34.3 bits (75), Expect = 0.65
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Frame = -2
Query: 274 SRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVSASTTS-CRRLSYTIGSK 116
S PP S PPP S +S L + SR + ESP+S S L Y G+K
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPALSPLGELEYPFGAK 689
>Z34277-1|CAA84031.1| 477|Homo sapiens mucin protein.
Length = 477
Score = 33.9 bits (74), Expect = 0.86
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 1/181 (0%)
Frame = -2
Query: 688 CASSAGRIVTDGIGWKPSSEAGKAGDPVQKYTKSCLSKCVILSTIAHSQRLKRASRSGCS 509
C + G VT PS+ +G+A P Q + S+ L T + + + ++ S +
Sbjct: 120 CETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTS--A 177
Query: 508 PLSSLKLV*ETRAATFISPTPFSSRRKSSAVKPSSADSGNTSRTPTRIASRAFS-*EINI 332
P +S T +T +PT ++ +++ + S ++ T + I++R S
Sbjct: 178 PTTSTTSAPTT--STTSAPTTSTTSTPQTSISSAPTSSTTSAPTSSTISARTTSIISAPT 235
Query: 331 LCWEYLRT*S*TLCAVTSSSRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVSASTT 152
T S T TS++ P SST P +S S + + SPV+ ++T
Sbjct: 236 TSTTSFPTTSTTSATTTSTTSAP-TSSTTSTPQTSKTSAATSSTTSGSGTTPSPVTTTST 294
Query: 151 S 149
+
Sbjct: 295 A 295
>AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein.
Length = 1349
Score = 33.9 bits (74), Expect = 0.86
Identities = 39/180 (21%), Positives = 76/180 (42%)
Frame = -2
Query: 688 CASSAGRIVTDGIGWKPSSEAGKAGDPVQKYTKSCLSKCVILSTIAHSQRLKRASRSGCS 509
C + G VT PS+ +G+A P Q + S+ L T + + + ++ S +
Sbjct: 296 CETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTS--A 353
Query: 508 PLSSLKLV*ETRAATFISPTPFSSRRKSSAVKPSSADSGNTSRTPTRIASRAFS*EINIL 329
P +S T +T +PT ++ +++ + S ++ T + I++R S
Sbjct: 354 PTTSTTSAPTT--STTSAPTTSTTSTPQTSISSAPTSSTTSAPTSSTISARTTSIISAPT 411
Query: 328 CWEYLRT*S*TLCAVTSSSRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVSASTTS 149
+ T A T+S+ SST P +S S + ++ SPV+ ++T+
Sbjct: 412 TSTTSSPTTSTTSATTTSTTSAPTSSTTSTPQTSKTSAATSSTTSSSGTTPSPVTTTSTA 471
Score = 32.3 bits (70), Expect = 2.6
Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 5/192 (2%)
Frame = -2
Query: 688 CASSAGRIVTDGIGWKPSSEAGKAGDPVQKYTKSCLSKCVILSTIAHSQRLKRASRSGCS 509
C + G VT PS+ +G+A P Q + S+ L T + + + ++ S +
Sbjct: 1027 CETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTSAPT 1086
Query: 508 PLSSLKLV*ETRAATFISPT--PFSSRRKSSAVKPSSADSGNTSRTPTRIASRAFS*EIN 335
+ T +A S T P +S + + +S + +T+ PT + A + N
Sbjct: 1087 TSTIPASTPSTTSAPTTSTTSAPTTSTTSAPTHRTTSGPTTSTTLAPTTSTTSAPTTSTN 1146
Query: 334 ILCWEYLRT*S*T--LCAVTSSSRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPV-S 164
+ S T + A T+S+ SST P +S S + + SPV +
Sbjct: 1147 SAPTTSTISASTTSTISAPTTSTISSPTSSTTSTPQTSKTSAATSSTTSGSGTTPSPVPT 1206
Query: 163 ASTTSCRRLSYT 128
STTS S T
Sbjct: 1207 TSTTSASTTSTT 1218
>BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein.
Length = 257
Score = 33.5 bits (73), Expect = 1.1
Identities = 45/174 (25%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Frame = -2
Query: 595 TKSCLSKCVILSTI---AHSQRLKRASRSGCSPLSSLKLV*ETRAATFISPTPFSSRRKS 425
++S LS ++ S+I + S +S S SP SS + +++ SP+ SS S
Sbjct: 42 SRSILSSSILSSSIPSSSSSSSSPSSSHSSSSPSSSHSSSSPSSSSSTSSPSS-SSSSSS 100
Query: 424 SAVKPSSADSGNTSRTPTRIASRAFS*EINILCWEYLRT*S*TLCAVTSSSRPPGMSSTQ 245
S+ S++ S ++S +P+ +S + S + + S + + +SSS P SS+
Sbjct: 101 SSPSSSNSSSSSSSSSPSSSSSSSSSSPSS-------SSSSPSSSSSSSSSSPSSSSSSP 153
Query: 244 PPPSSSHISKLKLRSRAAKSD*ESPVSASTTSCRRLSYTIGSKNAKSWNRIGRP 83
SSS S S ++ S S S+S +S S + S ++ R P
Sbjct: 154 SSSSSSSSSSSSSPSSSSPSSSGSSPSSSNSSPSSSSSSPSSSSSSPSPRSSSP 207
Score = 31.9 bits (69), Expect = 3.5
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 2/198 (1%)
Frame = -2
Query: 691 RCASSAGRIVTDGIGWKPS--SEAGKAGDPVQKYTKSCLSKCVILSTIAHSQRLKRASRS 518
R +SS+ R + S S + + P ++ S S S+ + S S S
Sbjct: 36 RSSSSSSRSILSSSILSSSIPSSSSSSSSPSSSHSSSSPSSSHSSSSPSSSSSTSSPSSS 95
Query: 517 GCSPLSSLKLV*ETRAATFISPTPFSSRRKSSAVKPSSADSGNTSRTPTRIASRAFS*EI 338
S SS + +++ SP+ SS SS SS+ S ++S + + +S + S
Sbjct: 96 SSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSPSSSSSSPSSSSSSSSSSPSSSSSSPSS 155
Query: 337 NILCWEYLRT*S*TLCAVTSSSRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVSAS 158
+ + S + + +SS P SS P SSS S + +S S S+S
Sbjct: 156 SSSSSSSSSS-SPSSSSPSSSGSSPS-SSNSSPSSSSSSPSSSSSSPSPRSSSPSSSSSS 213
Query: 157 TTSCRRLSYTIGSKNAKS 104
T+S S + S ++ S
Sbjct: 214 TSSPSTSSPSSSSPSSSS 231
>BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein.
Length = 502
Score = 31.1 bits (67), Expect = 6.1
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LT DL + + V DI + +Y + NDE P R+A W ++D + + DL
Sbjct: 300 LTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIP-FDL 358
Query: 594 VYFWTGS 614
+ F TGS
Sbjct: 359 LIFRTGS 365
>AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens
cDNA FLJ34558 fis, clone KIDNE2001636, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 905
Score = 31.1 bits (67), Expect = 6.1
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LT DL + + V DI + +Y + NDE P R+A W ++D + + DL
Sbjct: 300 LTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIP-FDL 358
Query: 594 VYFWTGS 614
+ F TGS
Sbjct: 359 LIFRTGS 365
>AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member 2
protein.
Length = 994
Score = 31.1 bits (67), Expect = 6.1
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 414 LTAEDLRLLLNGVGDINVAALVSYTSFNDESGEQPERLARFKRWLWAIVDKMTHLERQDL 593
LT DL + + V DI + +Y + NDE P R+A W ++D + + DL
Sbjct: 300 LTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIP-FDL 358
Query: 594 VYFWTGS 614
+ F TGS
Sbjct: 359 LIFRTGS 365
>AF010404-1|AAC51735.1| 4957|Homo sapiens ALR protein.
Length = 4957
Score = 30.7 bits (66), Expect = 8.0
Identities = 16/37 (43%), Positives = 20/37 (54%)
Frame = -2
Query: 274 SRPPGMSSTQPPPSSSHISKLKLRSRAAKSD*ESPVS 164
S PP S PPP S +S L + SR + ESP+S
Sbjct: 56 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 92
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,692,100
Number of Sequences: 237096
Number of extensions: 2422581
Number of successful extensions: 11641
Number of sequences better than 10.0: 147
Number of HSP's better than 10.0 without gapping: 10654
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11443
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12381054106
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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