Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP03_F_P03
(909 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5T9 Cluster: Adenylate cyclase; n=1; Bombyx mori|Rep... 357 2e-97
UniRef50_Q20034 Cluster: Putative uncharacterized protein; n=3; ... 155 2e-36
UniRef50_A1DU24 Cluster: Putative adenylate cyclase; n=3; Coelom... 143 5e-33
UniRef50_Q16QR3 Cluster: Putative uncharacterized protein; n=2; ... 142 1e-32
UniRef50_A3ZLV6 Cluster: Adenylate cyclase; n=6; cellular organi... 140 3e-32
UniRef50_UPI00015B5128 Cluster: PREDICTED: similar to putative a... 131 2e-29
UniRef50_Q9W3U9 Cluster: CG14434-PA; n=3; Diptera|Rep: CG14434-P... 131 2e-29
UniRef50_Q39L03 Cluster: Adenylate cyclase; n=27; Burkholderia|R... 124 3e-27
UniRef50_Q475C0 Cluster: Adenylate cyclase; n=5; Proteobacteria|... 116 6e-25
UniRef50_UPI0000DB7DC6 Cluster: PREDICTED: similar to CG14434-PA... 107 3e-22
UniRef50_Q2S8K3 Cluster: Adenylate cyclase, class 2; n=1; Hahell... 89 1e-16
UniRef50_A2A0K9 Cluster: Adenylate cyclase; n=1; Microscilla mar... 60 8e-08
UniRef50_A6BKT0 Cluster: Putative uncharacterized protein; n=1; ... 56 9e-07
UniRef50_Q2FP43 Cluster: Adenylyl cyclase CyaB, putative; n=1; M... 50 8e-05
UniRef50_Q9V028 Cluster: CyaB-like1 adenylyl cyclase, CyaB-type,... 46 0.001
UniRef50_Q0W8A4 Cluster: Adenylate cyclase; n=1; uncultured meth... 46 0.001
UniRef50_Q2NFC2 Cluster: Predicted adenylate cyclase; n=1; Metha... 42 0.016
UniRef50_A5KSE0 Cluster: Putative adenylyl cyclase CyaB; n=1; ca... 41 0.050
UniRef50_A6CF27 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_A3H6R3 Cluster: Putative adenylyl cyclase CyaB; n=1; Ca... 39 0.15
UniRef50_A3ZTE3 Cluster: Adenylyl cyclase related protein; n=1; ... 38 0.27
UniRef50_Q8ZYD0 Cluster: Adenylate cyclase; n=4; Pyrobaculum|Rep... 36 1.1
UniRef50_Q660F0 Cluster: Adenylyl cyclase, CyaB-type, putative; ... 36 1.9
UniRef50_Q9V1Q2 Cluster: Adenylate cyclase 2; n=5; Thermococcace... 35 2.5
UniRef50_Q9HQ74 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5
UniRef50_A2SSL0 Cluster: Putative adenylyl cyclase CyaB; n=2; Me... 35 3.3
UniRef50_Q00SF9 Cluster: Delta 6-fatty acid desaturase/delta-8 s... 34 4.4
UniRef50_Q5V2S6 Cluster: Adenylate cyclase; n=3; Halobacteriacea... 34 4.4
UniRef50_O77322 Cluster: Putative uncharacterized protein MAL3P3... 34 5.8
UniRef50_A7D3H7 Cluster: Putative adenylyl cyclase CyaB; n=1; Ha... 34 5.8
UniRef50_Q8WMR7 Cluster: Bestrophin-1; n=1; Sus scrofa|Rep: Best... 33 7.6
>UniRef50_Q2F5T9 Cluster: Adenylate cyclase; n=1; Bombyx mori|Rep:
Adenylate cyclase - Bombyx mori (Silk moth)
Length = 174
Score = 357 bits (879), Expect = 2e-97
Identities = 173/174 (99%), Positives = 173/174 (99%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY 302
MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY
Sbjct: 1 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY 60
Query: 303 DRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHID 482
DRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHID
Sbjct: 61 DRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHID 120
Query: 483 TVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDMLLKE 644
TVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQN DLIDNAYVDMLLKE
Sbjct: 121 TVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNEDLIDNAYVDMLLKE 174
>UniRef50_Q20034 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 174
Score = 155 bits (375), Expect = 2e-36
Identities = 82/173 (47%), Positives = 111/173 (64%), Gaps = 3/173 (1%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAAT---LV 296
RNVEIK K+++ D+ + A E+SG PT++KQ+DIFY+ NGRLKMR ++ L+
Sbjct: 3 RNVEIKAKVQNLDETVRRAVEISGKQPTILKQHDIFYESPNGRLKMRSVEENGVAHTELI 62
Query: 297 RYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIH 476
YDRS GPKL+N+ + + KL L+ +G +G V K R L + GQTRIH
Sbjct: 63 WYDRSDVAGPKLSNFNKFDVPSEVLDALKL---SLQSSMGVKGEVKKTRTLVLHGQTRIH 119
Query: 477 IDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
ID V LG FMELEV L+PE+T E G+KIA E+++ L V DL+ AY+DML
Sbjct: 120 IDRVDGLGDFMELEVCLSPEETPEHGEKIAHEIRELLAVPETDLLTGAYMDML 172
>UniRef50_A1DU24 Cluster: Putative adenylate cyclase; n=3;
Coelomata|Rep: Putative adenylate cyclase - Artemia
sanfranciscana (Brine shrimp) (Artemia franciscana)
Length = 173
Score = 143 bits (347), Expect = 5e-33
Identities = 74/171 (43%), Positives = 106/171 (61%), Gaps = 1/171 (0%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYD 305
+N EIK ++ D D + A LSG P +I Q+D F+ V NGRLK+R + + A L+ YD
Sbjct: 4 QNAEIKARVNDVDALEIAARRLSGRTPEIIFQDDTFFNVPNGRLKLRKFRNDAGELIFYD 63
Query: 306 RSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDT 485
R GPK++ Y + + + +L L+ LG +GRV K RKLYMV QTR+HID
Sbjct: 64 RPDSSGPKISTY-----SKTDTSEPDILAKTLEMALGIRGRVQKTRKLYMVDQTRVHIDK 118
Query: 486 VKDL-GHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
V+ L G + ELEV L +QT EDG+ IA +L ++LG+ DL+ AY+D++
Sbjct: 119 VEKLPGFYAELEVCLNEDQTPEDGKVIAEKLMEQLGIDKADLLTGAYLDLI 169
>UniRef50_Q16QR3 Cluster: Putative uncharacterized protein; n=2;
Endopterygota|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 184
Score = 142 bits (344), Expect = 1e-32
Identities = 68/175 (38%), Positives = 112/175 (64%), Gaps = 3/175 (1%)
Frame = +3
Query: 126 RNVEIKGKIRD---YDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLV 296
RN+EIK +I + + +A++L+G +IKQ+D+F+ GRLK+R+ + L+
Sbjct: 15 RNIEIKAQIAGPEAFQRKVAIAKQLTGSEGEIIKQHDVFFNAEKGRLKLRYLETKKSELI 74
Query: 297 RYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIH 476
+Y R GPKL+ Y + + ++ KL++ +L + +G +G V K R L++ GQTR+H
Sbjct: 75 QYFRPDVGGPKLSTYHKM-----DLDEPKLMETILAESIGIKGEVKKHRHLFLHGQTRVH 129
Query: 477 IDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDMLLK 641
+D V+ LGHF+E EVVL PEQ++++G KIA+++ K ++ LI AY+D LLK
Sbjct: 130 LDDVEGLGHFLEFEVVLRPEQSIDEGTKIANDMMKLFEIEEKALIQGAYMDKLLK 184
>UniRef50_A3ZLV6 Cluster: Adenylate cyclase; n=6; cellular
organisms|Rep: Adenylate cyclase - Blastopirellula
marina DSM 3645
Length = 178
Score = 140 bits (340), Expect = 3e-32
Identities = 72/170 (42%), Positives = 107/170 (62%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYD 305
RNVEIK ++ D ++ +A E++ P + Q D+F+ +GRLK+R D + L+ Y
Sbjct: 3 RNVEIKARVNDMSRLRHLAAEIANEGPWTLHQVDVFFHTASGRLKLRTINDEESELIYYH 62
Query: 306 RSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDT 485
R+ + GPK + Y ++ TA+ + + L LG G V K R LY+VGQTRIH+D
Sbjct: 63 RADQTGPKTSTY--VRTPTADPSGLRFV---LSAVLGELGEVRKRRTLYLVGQTRIHLDE 117
Query: 486 VKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
V DLG FMELEVVL +Q+V +G+KIA+EL K+ ++ DL D AY+D++
Sbjct: 118 VVDLGDFMELEVVLRDDQSVTEGEKIAAELMKRFEIRPADLCDGAYLDLI 167
>UniRef50_UPI00015B5128 Cluster: PREDICTED: similar to putative
adenylate cyclase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative adenylate cyclase -
Nasonia vitripennis
Length = 177
Score = 131 bits (317), Expect = 2e-29
Identities = 73/179 (40%), Positives = 108/179 (60%), Gaps = 6/179 (3%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNN------GRLKMRFYADSA 284
M+NVEIK K+ + D + + A++LS P +I Q+DIF+ V + GRLK+R + D
Sbjct: 1 MKNVEIKAKVDNIDHVEEKAKKLSDTPLVVIDQHDIFFHVPSNQAACGGRLKLRQFKDGT 60
Query: 285 ATLVRYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQ 464
L+ Y+R GPK + Y +++ + E+ + L +L + G G + K R LYMVGQ
Sbjct: 61 GELIYYERPDVTGPKTSTYSMVKL---DEERRRNLRVVLTQSNGVLGTIEKTRNLYMVGQ 117
Query: 465 TRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDMLLK 641
TRIHID V LG+F+ELEVVL + G++IA L K LG+ L+ AY+DM+L+
Sbjct: 118 TRIHIDRVLGLGNFLELEVVLNDGDDPKIGEEIAKNLMKDLGISENSLLSGAYMDMVLR 176
>UniRef50_Q9W3U9 Cluster: CG14434-PA; n=3; Diptera|Rep: CG14434-PA -
Drosophila melanogaster (Fruit fly)
Length = 187
Score = 131 bits (317), Expect = 2e-29
Identities = 75/179 (41%), Positives = 111/179 (62%), Gaps = 7/179 (3%)
Frame = +3
Query: 126 RNVEIKGKI----RDYDKICKVAEELSGGPPT-LIKQNDIFYKVN-NGRLKMRFY-ADSA 284
RNVE+K +I +++ +A LSG LI+Q D+F++ GRLK+R+ S
Sbjct: 11 RNVEVKARIPGGSEGFEQRLILARNLSGSQDAQLIEQRDVFFESPLGGRLKLRYLQTPSR 70
Query: 285 ATLVRYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQ 464
+ LV YDR GPKL+ +F E ++ ++L+ +L + G G + K R L++ GQ
Sbjct: 71 SQLVYYDRPDVAGPKLS-----KFNKTEVDEPEVLEKILSQSNGVLGVLAKRRHLFLCGQ 125
Query: 465 TRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDMLLK 641
TRIH+D VKDLG+FMELEV L +QT+E+GQ IA +L ++LG+Q DL+ +Y D L K
Sbjct: 126 TRIHLDEVKDLGYFMELEVCLTEDQTLEEGQAIAEKLSRELGIQEADLMIGSYFDALRK 184
>UniRef50_Q39L03 Cluster: Adenylate cyclase; n=27; Burkholderia|Rep:
Adenylate cyclase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 177
Score = 124 bits (299), Expect = 3e-27
Identities = 69/171 (40%), Positives = 98/171 (57%), Gaps = 1/171 (0%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSA-ATLVRY 302
RN+EIK + R++D++ + A L+ P +Q D FY V GRLK+R + D A L+ Y
Sbjct: 3 RNIEIKARAREFDQLREQAARLATEAPLFYRQQDFFYDVPRGRLKLRRFEDGTPAELIFY 62
Query: 303 DRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHID 482
R GPK A+Y +T + + +L L +G V KER +Y+ G+TRIH+D
Sbjct: 63 QRDDRDGPK-ASY----YTRSPVTNPDAMHALLATALTTRGIVTKERHVYLAGRTRIHLD 117
Query: 483 TVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
V LG F+ELEVVL P+ G+ A ++ KLGV DL+ AYVD+L
Sbjct: 118 RVDGLGDFIELEVVLGPDDDEAGGEAEAHDVFAKLGVSQDDLVAVAYVDLL 168
>UniRef50_Q475C0 Cluster: Adenylate cyclase; n=5;
Proteobacteria|Rep: Adenylate cyclase - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 179
Score = 116 bits (280), Expect = 6e-25
Identities = 68/170 (40%), Positives = 98/170 (57%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYD 305
RNVEIK ++ I L+ P I+Q+D F+ +NGRLK+R + L+ Y
Sbjct: 3 RNVEIKARLDSIGAIESRVAALANSGPERIEQDDTFFPCSNGRLKLRAFGPDRGQLIFYA 62
Query: 306 RSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDT 485
R+ + GPK + Y L + + +A L G GRV K R LY+VG+TR+H+D
Sbjct: 63 RADQAGPKESFYILSPTASPDTLRAALA-----AAQGEVGRVRKLRTLYLVGRTRVHLDR 117
Query: 486 VKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
V+ LG F+ELEVVLA +++V G A L ++LGV+ LI+ AYVD+L
Sbjct: 118 VEGLGDFLELEVVLADDESVAAGVAEAHGLLERLGVEAGALIEGAYVDLL 167
>UniRef50_UPI0000DB7DC6 Cluster: PREDICTED: similar to CG14434-PA,
partial; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG14434-PA, partial - Apis mellifera
Length = 122
Score = 107 bits (258), Expect = 3e-22
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +3
Query: 276 DSAATLVRYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYM 455
D + L+ Y RS GPKL +YE + + + ++L + G+ G V K RKLYM
Sbjct: 1 DGSGELIYYKRSNVFGPKLCDYEKVAL---DENACSGIANILNESNGSVGIVKKTRKLYM 57
Query: 456 VGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
+ QTR+HID V+ LG+F+ELEV+L +Q +E G+KIA +L KL +++ DLI NAY+D+L
Sbjct: 58 IDQTRVHIDDVEGLGNFLELEVILNDDQDIESGEKIAQDLMSKLDIKSEDLIANAYIDLL 117
Query: 636 LK 641
K
Sbjct: 118 SK 119
>UniRef50_Q2S8K3 Cluster: Adenylate cyclase, class 2; n=1; Hahella
chejuensis KCTC 2396|Rep: Adenylate cyclase, class 2 -
Hahella chejuensis (strain KCTC 2396)
Length = 168
Score = 89.0 bits (211), Expect = 1e-16
Identities = 55/170 (32%), Positives = 91/170 (53%)
Frame = +3
Query: 126 RNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYD 305
+N+E+K I + +A+++S P + Q DIFY +N GRLK+R + T + Y
Sbjct: 3 KNIELKFSIESMSEFVAMAKKISMESPVELMQKDIFYSINKGRLKLRD-ENGIKTFIYYF 61
Query: 306 RSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDT 485
RS KG +L+ Y +F + +++ +L LGA+G V K R++Y +RIH D+
Sbjct: 62 RSNCKGERLSRY--YRFRVGRL-LSNIVEVILSFILGARGIVSKRRRVYFYKNSRIHCDS 118
Query: 486 VKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
V LG F E EVV+ T ++ ++ L+ ++ L+ +Y DML
Sbjct: 119 VLGLGEFGEFEVVM-NGITEQEAREEVEFLRNHFCIKEKSLVSVSYSDML 167
>UniRef50_A2A0K9 Cluster: Adenylate cyclase; n=1; Microscilla marina
ATCC 23134|Rep: Adenylate cyclase - Microscilla marina
ATCC 23134
Length = 163
Score = 60.1 bits (139), Expect = 8e-08
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 1/162 (0%)
Frame = +3
Query: 132 VEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYDRS 311
VEIK + D+I E+ + Q D ++KV+ GRLK+R + L++Y R
Sbjct: 6 VEIKARTAKADQIRTFLEKNKTYFKGVDYQTDTYFKVHKGRLKLR-EGNIENHLIQYYRP 64
Query: 312 KEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDTVK 491
+ K + E+L + + L +L LG V K+R++Y + + HID V
Sbjct: 65 NQAEAKTS--EVLLYKS---NPESTLKQILTNALGELVVVKKKREIYFIDNVKFHIDEVD 119
Query: 492 DLGHFMELEVV-LAPEQTVEDGQKIASELQKKLGVQNVDLID 614
LG F E+E + E ED + Q+ LG++ DL++
Sbjct: 120 QLGSFAEIEAIGNKGEHLEEDLRAQCLHYQQLLGIRAEDLVE 161
>UniRef50_A6BKT0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 185
Score = 56.4 bits (130), Expect = 9e-07
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 4/112 (3%)
Frame = +3
Query: 318 KGPKLANYELLQFTTAE--YEKAKLLDDMLKKC--LGAQGRVVKERKLYMVGQTRIHIDT 485
KGPKL + + T YE K+ +D+LK+ A RV K R Y+ D
Sbjct: 72 KGPKLDQVSMTRKETEIDIYEPEKM-EDILKELEFYPASCRVKKTRCYYIKDHMTAAADK 130
Query: 486 VKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDMLLK 641
V++LG+F+ELE+++A E+ G + EL + LG + + + ++Y+ ML K
Sbjct: 131 VENLGNFLELEIIVAKEEERAGGLDMIYELMRMLGCEKTETVRDSYLSMLEK 182
>UniRef50_Q2FP43 Cluster: Adenylyl cyclase CyaB, putative; n=1;
Methanospirillum hungatei JF-1|Rep: Adenylyl cyclase
CyaB, putative - Methanospirillum hungatei (strain JF-1
/ DSM 864)
Length = 175
Score = 50.0 bits (114), Expect = 8e-05
Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLK-----MRFYADSAA 287
M +EIK K+ D+I K + G + + D++Y + +R +
Sbjct: 1 MLEIEIKVKVPHIDEIKKRILTIGGKHSETVVEEDLYYNAPHRDFAQTDEALRVRSAGGK 60
Query: 288 TLVRYDRSKEKGPK--LANYELLQFTTAEYEKAKLLDDMLKKCLGAQ--GRVVKERKLYM 455
T++ Y KGPK L ++ + + + A D +LK LG + V K R+ Y
Sbjct: 61 TILTY-----KGPKNTLMGSKIREECNVQLDNAGAFDTILKN-LGFKPVAHVRKLREYYT 114
Query: 456 VGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
I +D V LG F+E+E++ E E K EL + LGV + I +Y+++L
Sbjct: 115 YQDFSIALDNVDHLGEFVEIELI--TENNAEKAAKRVDELAETLGVVG-ERISISYLELL 171
Query: 636 L 638
L
Sbjct: 172 L 172
>UniRef50_Q9V028 Cluster: CyaB-like1 adenylyl cyclase, CyaB-type,
putative; n=4; Thermococcaceae|Rep: CyaB-like1 adenylyl
cyclase, CyaB-type, putative - Pyrococcus abyssi
Length = 170
Score = 46.4 bits (105), Expect = 0.001
Identities = 35/169 (20%), Positives = 85/169 (50%), Gaps = 1/169 (0%)
Frame = +3
Query: 132 VEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRL-KMRFYADSAATLVRYDR 308
+EI+ K R + I + E L+ L Q D+++ V +L ++R ++ + + Y
Sbjct: 1 MEIEIKFRVSEDIKERLESLNAKFVGLEVQEDVYFDVPLPKLLRVRRISNLGKSYITYKE 60
Query: 309 SKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDTV 488
++ + YE+ +F +++ A ++ + + + KER +Y +G ++ +
Sbjct: 61 IMDRNNE-EFYEV-EFEVSDFNLA--IEVFKRLGFDVKASIKKERLIYKLGDVTFELNKI 116
Query: 489 KDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDML 635
LG+F+++EV+ E+ ++ E+ +KLG++ D+ Y++++
Sbjct: 117 PGLGNFLDIEVI---SDDPEEAKRKIWEVAEKLGLKKKDVEPRLYIELV 162
>UniRef50_Q0W8A4 Cluster: Adenylate cyclase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Adenylate cyclase -
Uncultured methanogenic archaeon RC-I
Length = 176
Score = 46.4 bits (105), Expect = 0.001
Identities = 23/72 (31%), Positives = 45/72 (62%)
Frame = +3
Query: 429 VVKERKLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDL 608
V+KER++Y I +D V++LG F+E+E + ++ + + + ++LGV+ DL
Sbjct: 104 VIKERQIYHYKGAEICLDRVEELGEFVEVEAIAENQKEIGAKRDEVITILRELGVRG-DL 162
Query: 609 IDNAYVDMLLKE 644
I +Y++MLL++
Sbjct: 163 IRESYLEMLLQK 174
>UniRef50_Q2NFC2 Cluster: Predicted adenylate cyclase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Predicted
adenylate cyclase - Methanosphaera stadtmanae (strain
DSM 3091)
Length = 180
Score = 42.3 bits (95), Expect = 0.016
Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY 302
M VE+K KI + + + +E+ G KQ+DI++ N K A + R
Sbjct: 1 MIEVEMKAKINNNKEAFEKIKEIGGEYSHTEKQHDIYFNAPNKDYKETDEALRIREIPRD 60
Query: 303 DRSKE----KGPKLANYELLQFTTAEYE-KAKLLDDMLK--KCLGAQGRVV--KERKLYM 455
D + KGPKL + T E E D+M++ K LG + V K R+++
Sbjct: 61 DDFERILTYKGPKLDSKSK---TRKEVEVNIDDTDNMVEILKSLGFKPSAVVNKIRRIFN 117
Query: 456 VGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGV 593
+ I ID + LG++ME+E V ++ +E+ + ++ +KL +
Sbjct: 118 YDKYTITIDKLNRLGYYMEIEYVANKDEDIEEIRNNIIKVFEKLEI 163
>UniRef50_A5KSE0 Cluster: Putative adenylyl cyclase CyaB; n=1;
candidate division TM7 genomosp. GTL1|Rep: Putative
adenylyl cyclase CyaB - candidate division TM7 genomosp.
GTL1
Length = 189
Score = 40.7 bits (91), Expect = 0.050
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +3
Query: 429 VVKERKLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQ 596
V KER+ + +G + +DTVKDLG F+E E +TVE+ + KKLG +
Sbjct: 112 VDKEREEWKLGDIEVALDTVKDLGSFVEFE-YKGDARTVEEAHRKIEACIKKLGAK 166
>UniRef50_A6CF27 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 188
Score = 39.1 bits (87), Expect = 0.15
Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 13/185 (7%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY 302
M VE K +I D D++ +L I+Q+D ++ ++ D A + R
Sbjct: 1 MLEVEQKFRIHDKDQLIDQLAQLGATSGEPIEQHDYYFA---HPVRNFAETDEALRIRRN 57
Query: 303 ---DRSKEKGPKLANY-ELLQFTTAEYEKAKLLDDMLKKCLGAQG----RVVKERKL--- 449
+R KGPK A ++ + +E + + L + L G R VK+R+
Sbjct: 58 GTDNRITYKGPKRATVSKVRKEIELGFESGESAFEQLAETLELLGFEQVRTVKKRRTPYA 117
Query: 450 YMVGQT--RIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAY 623
Y Q I ID V++LG F E+E +LA E + + EL K LG+ N I +Y
Sbjct: 118 YAHNQQTFEITIDEVQELGTFAEIE-LLAEEDQLAAAEAAIIELAKSLGLSN--QIRLSY 174
Query: 624 VDMLL 638
+ ML+
Sbjct: 175 LGMLM 179
>UniRef50_A3H6R3 Cluster: Putative adenylyl cyclase CyaB; n=1;
Caldivirga maquilingensis IC-167|Rep: Putative adenylyl
cyclase CyaB - Caldivirga maquilingensis IC-167
Length = 184
Score = 39.1 bits (87), Expect = 0.15
Identities = 42/184 (22%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIF------YKVNNGRLKMRFYADSA 284
M VE+K ++ D + I + ++++ F + + +++R Y
Sbjct: 1 MFEVEVKFRVSDVNDIVGKLRSFATYVGNDVEEDHYFNHPCRDFATTDEAIRVRLYGSGK 60
Query: 285 ATLVRYDRSKEKGPKLANYELLQFT-TAEYEKAKLLDDMLKKCLGAQGRVV--KERKLYM 455
T V Y KGP+L+ ++ + + A +LK LG + V KER Y
Sbjct: 61 VT-VTY-----KGPRLSGEGKVRVEYNIDVDSASNTIGVLK-ALGFREIAVIRKERAEYT 113
Query: 456 VGQTRIHIDTVKDLGHFMELEVVLAPEQTV-EDGQKIASELQKKLGVQNVDLIDNAYVDM 632
G I++D V +LG F+E+E + + V E + I ++ LG++ + Y+++
Sbjct: 114 YGNYTIYVDKVNELGDFLEIETLTNDQGMVGELVKNIMGFARRNLGIKEDSVEPKTYLEL 173
Query: 633 LLKE 644
+L +
Sbjct: 174 ILSK 177
>UniRef50_A3ZTE3 Cluster: Adenylyl cyclase related protein; n=1;
Blastopirellula marina DSM 3645|Rep: Adenylyl cyclase
related protein - Blastopirellula marina DSM 3645
Length = 182
Score = 38.3 bits (85), Expect = 0.27
Identities = 47/184 (25%), Positives = 81/184 (44%), Gaps = 14/184 (7%)
Frame = +3
Query: 132 VEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRYDRS 311
VE+K + D ++ +L +KQ+D +Y G F A +R S
Sbjct: 5 VELKFPVNDLRRVETALADLGAAIEIPVKQSDFYY----GHPARDFAQTDEALRIRRVGS 60
Query: 312 KE----KGPKL-----ANYELLQFTTAEYEKAKLLDDMLKKCLGAQ-GRVVKERK---LY 452
K KGPK+ E+ + E A + DM++ Q V K R+ L
Sbjct: 61 KNIITYKGPKIDATTKTRREIEVPLVSGAEGAANIIDMIEALGFLQVAEVTKNRRKANLS 120
Query: 453 MVGQT-RIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVD 629
Q + +D VK LG F+ELE + E V+ ++ ++L +KLG+ + +Y++
Sbjct: 121 FADQAVEVALDEVKGLGEFVELE-ISTNEDGVDAAREAINQLAEKLGLSGSE--RRSYLE 177
Query: 630 MLLK 641
++L+
Sbjct: 178 LILE 181
>UniRef50_Q8ZYD0 Cluster: Adenylate cyclase; n=4; Pyrobaculum|Rep:
Adenylate cyclase - Pyrobaculum aerophilum
Length = 176
Score = 36.3 bits (80), Expect = 1.1
Identities = 32/161 (19%), Positives = 67/161 (41%), Gaps = 4/161 (2%)
Frame = +3
Query: 123 MRNVEIKGKIRDYDKICKVAEELSGGPPTLIKQNDIFYKVNNGRLKMRFYADSAATLVRY 302
M VE+K + D + + L P +++ + D++++ F A A VR
Sbjct: 1 MLEVEVKYRA-DLSLVKNRLQHLGFSPVSVVYEEDVYFQ----HPCRDFSATDEALRVRI 55
Query: 303 DRSKE----KGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTR 470
+ KGP++ + + ++++ + + A + K R+ Y G
Sbjct: 56 SEGRVTVTYKGPRMGAGAKTRLEVSAQASGEVVELLNRLGFKAVAVIKKRREYYRNGDVL 115
Query: 471 IHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGV 593
+ +D V+ LG F+E+E ++ E + + L LG+
Sbjct: 116 LSLDYVEGLGEFVEIEKMVEEESQIASAIEEIRRLASTLGL 156
>UniRef50_Q660F0 Cluster: Adenylyl cyclase, CyaB-type, putative;
n=3; Borrelia burgdorferi group|Rep: Adenylyl cyclase,
CyaB-type, putative - Borrelia garinii
Length = 176
Score = 35.5 bits (78), Expect = 1.9
Identities = 15/68 (22%), Positives = 37/68 (54%)
Frame = +3
Query: 432 VKERKLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLI 611
+K+ +Y + I+ +K+LG F+E+E ++ + ++ +K + + G+Q +L
Sbjct: 102 IKKSLIYQTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIHNIINQFGLQE-NLE 160
Query: 612 DNAYVDML 635
+Y ++L
Sbjct: 161 TRSYFELL 168
>UniRef50_Q9V1Q2 Cluster: Adenylate cyclase 2; n=5;
Thermococcaceae|Rep: Adenylate cyclase 2 - Pyrococcus
abyssi
Length = 183
Score = 35.1 bits (77), Expect = 2.5
Identities = 20/73 (27%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +3
Query: 426 RVVKERKLYMVGQ-TRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNV 602
R+VK R+ Y V + I +D V+ LG F+E+E ++ ++ + + + + LGV+
Sbjct: 105 RIVKTREKYYVDKGITITLDEVEGLGKFIEIETLVKEKEEIPRTVEKLEGILRNLGVERF 164
Query: 603 DLIDNAYVDMLLK 641
+ +Y+++LL+
Sbjct: 165 E--RKSYLELLLE 175
>UniRef50_Q9HQ74 Cluster: Putative uncharacterized protein; n=1;
Halobacterium salinarum|Rep: Putative uncharacterized
protein - Halobacterium salinarium (Halobacterium
halobium)
Length = 203
Score = 35.1 bits (77), Expect = 2.5
Identities = 14/52 (26%), Positives = 30/52 (57%)
Frame = +3
Query: 477 IDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAYVDM 632
+D V+D+G ++E+E + E V ++ A + ++LG+ D I +Y+ +
Sbjct: 147 LDAVEDVGEYVEIETTVEAEHAVSGAREDAYAVLRRLGLDPTDQIRTSYLGL 198
>UniRef50_A2SSL0 Cluster: Putative adenylyl cyclase CyaB; n=2;
Methanomicrobiales|Rep: Putative adenylyl cyclase CyaB -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 199
Score = 34.7 bits (76), Expect = 3.3
Identities = 42/185 (22%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Frame = +3
Query: 132 VEIKGKIRDYDKICKVAEELSGGPPTLIK---QNDIFYK-------VNNGRLKMRFYADS 281
+EIK K+ D I E+L LI ++D++Y V + L++R+ +
Sbjct: 19 IEIKVKVPSLDPI---REKLIASGAELIADQVEHDLYYNAPHRDFAVTDEALRIRYLTNQ 75
Query: 282 AATLVRYDRSKEKGPKL------ANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRVVKER 443
KGPK+ + EL+ ++ E +L+ L CL A+ VVK R
Sbjct: 76 ICGKAMPPNVTYKGPKVGREGFKSREELIVDLSSAEEYCTILE-RLGFCLTAE--VVKHR 132
Query: 444 KLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDLIDNAY 623
++Y + +DT+ +G F E+E + + ++ + ++ + G+ + + +Y
Sbjct: 133 EMYQCENALVTLDTLPGIGTFSEIEASF--DLSEDEAIAVINKTAEMAGIVG-ERLTKSY 189
Query: 624 VDMLL 638
+++LL
Sbjct: 190 LEILL 194
>UniRef50_Q00SF9 Cluster: Delta 6-fatty acid desaturase/delta-8
sphingolipid desaturase; n=2; Ostreococcus|Rep: Delta
6-fatty acid desaturase/delta-8 sphingolipid desaturase
- Ostreococcus tauri
Length = 691
Score = 34.3 bits (75), Expect = 4.4
Identities = 15/53 (28%), Positives = 30/53 (56%)
Frame = +3
Query: 273 ADSAATLVRYDRSKEKGPKLANYELLQFTTAEYEKAKLLDDMLKKCLGAQGRV 431
+D + ++ ++ KE+ +LA E+LQ TT + E + +L++C+ G V
Sbjct: 449 SDESRLIIANNQGKERSVRLARREILQVTTRDGETFPVHRSLLRQCISLTGAV 501
>UniRef50_Q5V2S6 Cluster: Adenylate cyclase; n=3;
Halobacteriaceae|Rep: Adenylate cyclase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 180
Score = 34.3 bits (75), Expect = 4.4
Identities = 21/72 (29%), Positives = 39/72 (54%)
Frame = +3
Query: 429 VVKERKLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDL 608
V K R++Y V + + +D V D+G F+E+E + +E ++ A E+ + L + D
Sbjct: 108 VRKNRRVYEVREYDVTLDAVDDVGEFVEVE--RETDGDIEPVREGAYEVLRDLSLNPNDQ 165
Query: 609 IDNAYVDMLLKE 644
+Y+ MLL +
Sbjct: 166 QRTSYLGMLLSD 177
>UniRef50_O77322 Cluster: Putative uncharacterized protein MAL3P3.5;
n=2; Plasmodium|Rep: Putative uncharacterized protein
MAL3P3.5 - Plasmodium falciparum (isolate 3D7)
Length = 1711
Score = 33.9 bits (74), Expect = 5.8
Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
Frame = +3
Query: 363 AEYEKAKLLDDMLKKCLGAQGRVVKERKLYMVGQTRIHIDTVKD-LGHFM-ELEVVLAPE 536
+++EK + + C+ R +K Y + ++ D +G E+E E
Sbjct: 691 SKWEKRTVSVRSIYLCIHTHSRYIKRSNKYQNDEFDENVSHKNDAVGSIAYEMEQNEINE 750
Query: 537 QTVEDGQKIA-SELQKKLGVQNVDLIDNAYVDMLLKE*CL--ANLSTSIKN 680
Q DG+ + E++ + ++N + IDNA ++ KE CL N+S ++ N
Sbjct: 751 QERRDGEMLGVDEMENRNKIENYEHIDNASSEISNKENCLIQKNMSNNLSN 801
>UniRef50_A7D3H7 Cluster: Putative adenylyl cyclase CyaB; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Putative
adenylyl cyclase CyaB - Halorubrum lacusprofundi ATCC
49239
Length = 200
Score = 33.9 bits (74), Expect = 5.8
Identities = 18/72 (25%), Positives = 35/72 (48%)
Frame = +3
Query: 429 VVKERKLYMVGQTRIHIDTVKDLGHFMELEVVLAPEQTVEDGQKIASELQKKLGVQNVDL 608
V K R+ + + +D V +G F+E+E + E +E + A E +LG+
Sbjct: 124 VEKRREFWSFAGFTVTLDAVDGVGEFVEIEREVDDESAIEATRDEALEALDRLGLDGDSQ 183
Query: 609 IDNAYVDMLLKE 644
I +Y+ ++L +
Sbjct: 184 IRTSYLGLMLAD 195
>UniRef50_Q8WMR7 Cluster: Bestrophin-1; n=1; Sus scrofa|Rep:
Bestrophin-1 - Sus scrofa (Pig)
Length = 428
Score = 33.5 bits (73), Expect = 7.6
Identities = 18/51 (35%), Positives = 23/51 (45%)
Frame = +2
Query: 422 RPCCERTKTVHGWPDTYTHRHS*RPRTLYGARSSISSGTDS*RWSEDRFRT 574
+P +KT WP H H P+ L GAR S DS W E F++
Sbjct: 247 QPPRTNSKTKLLWPKKEGHFHEGHPKNLRGARLDSSDQEDSKAWREGGFKS 297
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 793,761,637
Number of Sequences: 1657284
Number of extensions: 15003477
Number of successful extensions: 32892
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 31790
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32862
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 82801539422
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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