Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP03_F_E08
(914 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55B5F Cluster: PREDICTED: similar to Caspase pr... 207 3e-52
UniRef50_O01382 Cluster: Caspase precursor (EC 3.4.22.-) (drICE)... 203 6e-51
UniRef50_UPI00015B4D75 Cluster: PREDICTED: similar to CG7788-PA;... 151 2e-35
UniRef50_Q7Q1E0 Cluster: ENSANGP00000015118; n=2; Culicidae|Rep:... 142 8e-33
UniRef50_UPI00015B57EE Cluster: PREDICTED: similar to ENSANGP000... 140 6e-32
UniRef50_UPI0000E49D20 Cluster: PREDICTED: hypothetical protein;... 139 8e-32
UniRef50_Q7Q803 Cluster: ENSANGP00000021367; n=6; Anopheles gamb... 133 5e-30
UniRef50_Q17FE3 Cluster: Caspase-1; n=3; Endopterygota|Rep: Casp... 133 7e-30
UniRef50_Q7Q802 Cluster: ENSANGP00000021365; n=4; Cellia|Rep: EN... 127 5e-28
UniRef50_P55212 Cluster: Caspase-6 precursor (EC 3.4.22.59) (CAS... 120 5e-26
UniRef50_Q9NHF9 Cluster: Caspase 6-like protein BG2; n=3; Sophop... 119 1e-25
UniRef50_UPI0000519DFF Cluster: PREDICTED: similar to Caspase pr... 116 8e-25
UniRef50_UPI0000F21D96 Cluster: PREDICTED: hypothetical protein,... 114 3e-24
UniRef50_Q2TM51 Cluster: Caspase; n=3; Penaeidae|Rep: Caspase - ... 113 6e-24
UniRef50_Q92851 Cluster: Caspase-10 precursor (EC 3.4.22.63) (CA... 111 2e-23
UniRef50_UPI0000F2DFE7 Cluster: PREDICTED: similar to apoptotic ... 111 2e-23
UniRef50_Q8ITP2 Cluster: AmphiCASP-6; n=2; Chordata|Rep: AmphiCA... 111 2e-23
UniRef50_Q69HP8 Cluster: Caspase-1-like; n=1; Ciona intestinalis... 111 3e-23
UniRef50_Q92851-2 Cluster: Isoform B of Q92851 ; n=9; Mammalia|R... 108 2e-22
UniRef50_A1L2P4 Cluster: LOC100036910 protein; n=1; Xenopus laev... 105 2e-21
UniRef50_P55210 Cluster: Caspase-7 precursor (EC 3.4.22.60) (CAS... 105 2e-21
UniRef50_UPI0000F2097E Cluster: PREDICTED: hypothetical protein;... 105 2e-21
UniRef50_UPI0001554FA5 Cluster: PREDICTED: similar to initiator ... 104 3e-21
UniRef50_UPI0000586459 Cluster: PREDICTED: similar to caspase-3,... 103 5e-21
UniRef50_Q7QKT2 Cluster: ENSANGP00000015505; n=3; Anopheles gamb... 103 6e-21
UniRef50_UPI0000E48555 Cluster: PREDICTED: similar to Lice2 cyst... 102 1e-20
UniRef50_Q98UI8 Cluster: Caspase-3; n=4; Chordata|Rep: Caspase-3... 100 4e-20
UniRef50_Q56VC9 Cluster: Caspase-8; n=3; Euteleostei|Rep: Caspas... 100 1e-19
UniRef50_Q14790 Cluster: Caspase-8 precursor (EC 3.4.22.61) (CAS... 99 1e-19
UniRef50_Q5DD62 Cluster: SJCHGC00800 protein; n=3; Schistosoma j... 99 2e-19
UniRef50_Q9IB62 Cluster: Caspase-10; n=5; Xenopus|Rep: Caspase-1... 98 2e-19
UniRef50_Q4SC67 Cluster: Chromosome undetermined SCAF14659, whol... 98 2e-19
UniRef50_UPI0000E472FD Cluster: PREDICTED: similar to caspase 8;... 97 7e-19
UniRef50_Q8I6Y2 Cluster: Caspase-3; n=2; Geodia cydonium|Rep: Ca... 96 1e-18
UniRef50_Q4JQQ0 Cluster: Initiator caspase; n=2; Gallus gallus|R... 96 1e-18
UniRef50_Q3HL92 Cluster: Caspase-like protein; n=6; Eumetazoa|Re... 96 1e-18
UniRef50_A7SPA7 Cluster: Predicted protein; n=1; Nematostella ve... 95 2e-18
UniRef50_A2BGE2 Cluster: Novel protein similar to caspase 8; n=4... 95 2e-18
UniRef50_Q90WU0 Cluster: Caspase 9; n=2; Gallus gallus|Rep: Casp... 95 3e-18
UniRef50_Q4V923 Cluster: Zgc:101776 protein; n=8; Clupeocephala|... 95 3e-18
UniRef50_Q0Z855 Cluster: Caspase-2; n=1; Haemaphysalis longicorn... 95 3e-18
UniRef50_Q0WYJ4 Cluster: Caspase 10; n=4; Percomorpha|Rep: Caspa... 93 9e-18
UniRef50_Q6E5N8 Cluster: Caspase 8; n=1; Ictalurus punctatus|Rep... 91 3e-17
UniRef50_UPI0000ECB87F Cluster: Caspase-10 precursor (EC 3.4.22.... 91 4e-17
UniRef50_UPI0000F2DFE8 Cluster: PREDICTED: similar to initiator ... 91 5e-17
UniRef50_Q2HZ04 Cluster: ICE-5; n=3; Bombyx mori|Rep: ICE-5 - Bo... 90 8e-17
UniRef50_P55213 Cluster: Caspase-3 precursor (EC 3.4.22.56) (CAS... 88 3e-16
UniRef50_Q09HM6 Cluster: Caspase-8; n=1; Molgula tectiformis|Rep... 87 6e-16
UniRef50_UPI000051A33A Cluster: PREDICTED: similar to CG6597-PA,... 86 1e-15
UniRef50_Q9I8J3 Cluster: Caspase-8; n=11; Danio rerio|Rep: Caspa... 84 4e-15
UniRef50_Q4RG79 Cluster: Chromosome 2 SCAF15106, whole genome sh... 84 5e-15
UniRef50_Q0PKX0 Cluster: Caspase Xa; n=4; Danio rerio|Rep: Caspa... 84 5e-15
UniRef50_Q0Z8U7 Cluster: Caspase-8; n=1; Haemaphysalis longicorn... 83 1e-14
UniRef50_Q7ZXD2 Cluster: MGC53258 protein; n=3; Xenopus|Rep: MGC... 82 2e-14
UniRef50_P42575 Cluster: Caspase-2 precursor (EC 3.4.22.55) (CAS... 82 2e-14
UniRef50_Q8JIS8 Cluster: Caspase 3A; n=3; Euteleostomi|Rep: Casp... 81 5e-14
UniRef50_A7S4V9 Cluster: Predicted protein; n=2; Nematostella ve... 79 2e-13
UniRef50_Q6KF63 Cluster: Caspase 10; n=3; Catarrhini|Rep: Caspas... 79 2e-13
UniRef50_UPI0000F1EBE3 Cluster: PREDICTED: similar to caspase 10... 78 3e-13
UniRef50_UPI0000E45DDA Cluster: PREDICTED: similar to caspase 3;... 78 3e-13
UniRef50_Q4SNC6 Cluster: Chromosome 8 SCAF14543, whole genome sh... 78 3e-13
UniRef50_Q4FJK5 Cluster: Casp9 protein; n=20; Eutheria|Rep: Casp... 78 4e-13
UniRef50_Q5D0W5 Cluster: Caspase 3C; n=2; Hydra vulgaris|Rep: Ca... 77 5e-13
UniRef50_A7S119 Cluster: Predicted protein; n=1; Nematostella ve... 77 5e-13
UniRef50_A7S9L1 Cluster: Predicted protein; n=1; Nematostella ve... 77 8e-13
UniRef50_P42573 Cluster: Cell death protein 3 precursor (EC 3.4.... 77 8e-13
UniRef50_P55211 Cluster: Caspase-9 precursor (EC 3.4.22.62) (CAS... 77 8e-13
UniRef50_Q9IB64 Cluster: Caspase-8; n=1; Xenopus laevis|Rep: Cas... 75 2e-12
UniRef50_Q8I749 Cluster: Caspase-related protein; n=1; Suberites... 75 3e-12
UniRef50_Q07BT4 Cluster: Caspase-1; n=2; Percomorpha|Rep: Caspas... 73 1e-11
UniRef50_Q16PQ5 Cluster: Ecdysone-inducible caspase, putative; n... 72 2e-11
UniRef50_UPI0000E48C15 Cluster: PREDICTED: similar to caspase 8;... 71 3e-11
UniRef50_UPI0000E82482 Cluster: PREDICTED: hypothetical protein;... 71 4e-11
UniRef50_Q9Y1U6 Cluster: Cell death protein CED-3; n=1; Pristion... 70 7e-11
UniRef50_Q9TZP6 Cluster: Caspase-related protein 1B; n=3; Caenor... 70 7e-11
UniRef50_UPI0000661247 Cluster: Homolog of Brachydanio rerio "Ca... 69 1e-10
UniRef50_UPI0000587370 Cluster: PREDICTED: similar to caspase 8,... 69 2e-10
UniRef50_UPI000065FEF6 Cluster: Homolog of Ictalurus punctatus "... 69 2e-10
UniRef50_Q9GV89 Cluster: Caspase 3A; n=1; Hydra vulgaris|Rep: Ca... 69 2e-10
UniRef50_P29466-4 Cluster: Isoform Delta of P29466 ; n=2; Euarch... 68 3e-10
UniRef50_Q504J1 Cluster: Caspase b; n=7; Danio rerio|Rep: Caspas... 68 3e-10
UniRef50_UPI0000E47F37 Cluster: PREDICTED: similar to caspase-3,... 68 4e-10
UniRef50_Q9I9L7 Cluster: Caspase; n=2; Danio rerio|Rep: Caspase ... 67 5e-10
UniRef50_Q5SVL3 Cluster: Caspase 7, apoptosis-related cysteine p... 67 7e-10
UniRef50_UPI0000E4A098 Cluster: PREDICTED: similar to CGI-141 pr... 66 9e-10
UniRef50_Q5C0Y4 Cluster: SJCHGC07329 protein; n=1; Schistosoma j... 66 1e-09
UniRef50_P29466-2 Cluster: Isoform Beta of P29466 ; n=11; Theria... 66 2e-09
UniRef50_P29466 Cluster: Caspase-1 precursor (EC 3.4.22.36) (CAS... 66 2e-09
UniRef50_UPI0000F2CF2E Cluster: PREDICTED: similar to caspase 12... 65 3e-09
UniRef50_UPI00006A1E20 Cluster: Caspase-9 precursor (EC 3.4.22.6... 64 4e-09
UniRef50_Q28GK9 Cluster: Novel protein; n=1; Xenopus tropicalis|... 64 4e-09
UniRef50_P49662 Cluster: Caspase-4 precursor (EC 3.4.22.57) (CAS... 63 8e-09
UniRef50_Q9Y055 Cluster: Caspase-related protein 2A; n=3; Caenor... 63 1e-08
UniRef50_UPI0000F1EFFE Cluster: PREDICTED: hypothetical protein;... 62 1e-08
UniRef50_Q16FR8 Cluster: Caspase-1; n=1; Aedes aegypti|Rep: Casp... 62 3e-08
UniRef50_P51878 Cluster: Caspase-5 precursor (EC 3.4.22.58) (CAS... 62 3e-08
UniRef50_P55865 Cluster: Caspase-1-A precursor; n=3; Xenopus|Rep... 62 3e-08
UniRef50_UPI00015B59A2 Cluster: PREDICTED: similar to ecdysone-i... 61 3e-08
UniRef50_O08736 Cluster: Caspase-12 precursor; n=12; Eutheria|Re... 61 3e-08
UniRef50_UPI0000D56041 Cluster: PREDICTED: similar to CG7486-PB,... 61 4e-08
UniRef50_A3QVU6 Cluster: Initiator caspase; n=3; Culicidae|Rep: ... 60 6e-08
UniRef50_UPI0000D57084 Cluster: PREDICTED: similar to CG8091-PA;... 60 8e-08
UniRef50_UPI0000F2CF2D Cluster: PREDICTED: similar to evolutiona... 59 1e-07
UniRef50_Q7KHK9 Cluster: DREAM; n=2; Sophophora|Rep: DREAM - Dro... 59 1e-07
UniRef50_P31944 Cluster: Caspase-14 precursor (EC 3.4.22.-) (CAS... 59 2e-07
UniRef50_Q9NBW3 Cluster: Cysteine protease; n=4; melanogaster su... 58 2e-07
UniRef50_Q4S1R8 Cluster: Chromosome undetermined SCAF14764, whol... 58 3e-07
UniRef50_Q7QGN0 Cluster: ENSANGP00000018113; n=4; Anopheles gamb... 58 4e-07
UniRef50_Q5BLH4 Cluster: Caspase c; n=4; Danio rerio|Rep: Caspas... 56 1e-06
UniRef50_Q5E9C1 Cluster: Caspase-4 precursor (EC 3.4.22.57) (CAS... 56 2e-06
UniRef50_UPI00015553DC Cluster: PREDICTED: similar to caspase-15... 54 5e-06
UniRef50_O42284 Cluster: Caspase-1; n=3; Gallus gallus|Rep: Casp... 54 7e-06
UniRef50_Q3T2L0 Cluster: Caspase-15; n=11; Theria|Rep: Caspase-1... 54 7e-06
UniRef50_UPI000065DDFC Cluster: CASP8 and FADD-like apoptosis re... 53 1e-05
UniRef50_A5JSK5 Cluster: Cysteine protease; n=2; Eukaryota|Rep: ... 53 1e-05
UniRef50_Q498I3 Cluster: LOC780745 protein; n=6; Xenopus|Rep: LO... 52 2e-05
UniRef50_Q28XB8 Cluster: GA14832-PA; n=1; Drosophila pseudoobscu... 52 3e-05
UniRef50_A6NFM5 Cluster: Uncharacterized protein ENSP00000371619... 51 4e-05
UniRef50_O15519-8 Cluster: Isoform 8 of O15519 ; n=3; Homo/Pan/G... 49 1e-04
UniRef50_O15519 Cluster: CASP8 and FADD-like apoptosis regulator... 49 1e-04
UniRef50_Q4RQQ1 Cluster: Chromosome 2 SCAF15004, whole genome sh... 47 6e-04
UniRef50_Q9XYF4 Cluster: Caspase Nc precursor (EC 3.4.22.-) (NED... 47 6e-04
UniRef50_Q178B7 Cluster: Caspase-3; n=2; Aedes aegypti|Rep: Casp... 46 0.001
UniRef50_UPI0000F2CF2F Cluster: PREDICTED: similar to caspase 12... 45 0.002
UniRef50_UPI00015B57F0 Cluster: PREDICTED: similar to GA20532-PA... 45 0.003
UniRef50_A7SXL6 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.003
UniRef50_Q8IRY7 Cluster: Caspase-8 precursor (EC 3.4.22.61) (Dea... 45 0.003
UniRef50_UPI000155BC01 Cluster: PREDICTED: similar to cellular F... 44 0.004
UniRef50_A2I5C3 Cluster: Putative caspase 3; n=1; Mytilus gallop... 44 0.004
UniRef50_A7M858 Cluster: Caspase-like protease; n=1; Suberites d... 41 0.038
UniRef50_UPI0000DB7195 Cluster: PREDICTED: similar to caspase 10... 41 0.051
UniRef50_A5K522 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_UPI0000E4A029 Cluster: PREDICTED: similar to PDZ domain... 38 0.47
UniRef50_UPI0000587146 Cluster: PREDICTED: similar to caspase Xa... 37 0.62
UniRef50_Q54VI5 Cluster: Putative uncharacterized protein; n=1; ... 32 1.4
UniRef50_Q896Y6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_Q03703 Cluster: Uncharacterized protein YML037C; n=2; S... 36 1.9
UniRef50_Q638E4 Cluster: Membrane associated protein; n=11; Baci... 35 2.5
UniRef50_A0BJS7 Cluster: Chromosome undetermined scaffold_110, w... 35 2.5
UniRef50_Q9UTJ8 Cluster: DNA repair protein rad50; n=1; Schizosa... 35 2.5
UniRef50_Q7RPC2 Cluster: Putative uncharacterized protein PY0153... 35 3.3
UniRef50_Q9U0J3 Cluster: Putative uncharacterized protein PFD046... 34 4.4
UniRef50_Q8IEM2 Cluster: Protein phosphatase 2c-like protein, pu... 34 5.8
UniRef50_O77033 Cluster: TRFA; n=2; Dictyostelium discoideum|Rep... 34 5.8
UniRef50_O76627 Cluster: Putative uncharacterized protein; n=1; ... 34 5.8
UniRef50_A4QWM4 Cluster: Putative uncharacterized protein; n=1; ... 34 5.8
UniRef50_Q5K5C1 Cluster: Caspase 7-like protein; n=1; Spodoptera... 33 7.7
UniRef50_A0BZ43 Cluster: Chromosome undetermined scaffold_138, w... 33 7.7
>UniRef50_UPI0000D55B5F Cluster: PREDICTED: similar to Caspase
precursor (drICE); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Caspase precursor (drICE) -
Tribolium castaneum
Length = 309
Score = 207 bits (506), Expect = 3e-52
Identities = 98/176 (55%), Positives = 128/176 (72%), Gaps = 6/176 (3%)
Frame = +1
Query: 178 NNGSGTEQR--KNGNE-DEGDAW-GSHGSS--QGRRYAKMPVERYAHYYNMNHNNRGMAI 339
NN G ++ +NG++ D+ DA + G+ A MP E+YA +YNMNH NRG+A+
Sbjct: 14 NNHEGEKENNVENGHDNDQSDALPDAFGTKLISNNVVACMPAEKYATHYNMNHKNRGLAL 73
Query: 340 IFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHT 519
IFNHE F+IHNLK RTGT+ D +L VLR LGF V V +LR DI R I+Q ++ DHT
Sbjct: 74 IFNHEVFDIHNLKPRTGTDQDRKNLEDVLRKLGFEVIVFQDLRYHDIERQIKQAAKYDHT 133
Query: 520 DNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
D+DCL ++VL+HG+ G+LYA+DT YKPD LW YF AD+CP+LAGKPK+FF+QACQG
Sbjct: 134 DSDCLCISVLTHGDTGILYARDTQYKPDLLWSYFAADRCPSLAGKPKIFFLQACQG 189
Score = 44.0 bits (99), Expect = 0.005
Identities = 21/33 (63%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
Frame = +2
Query: 683 KGDKLDGGITLSNTETDG-XXXXXYRIPIHADF 778
+GDKLDGG+ LS TETDG YRIP ADF
Sbjct: 188 QGDKLDGGVILSRTETDGHLEIDSYRIPAQADF 220
>UniRef50_O01382 Cluster: Caspase precursor (EC 3.4.22.-) (drICE)
[Contains: Caspase subunit p21; Caspase subunit p12];
n=13; Endopterygota|Rep: Caspase precursor (EC 3.4.22.-)
(drICE) [Contains: Caspase subunit p21; Caspase subunit
p12] - Drosophila melanogaster (Fruit fly)
Length = 339
Score = 203 bits (495), Expect = 6e-51
Identities = 90/153 (58%), Positives = 117/153 (76%)
Frame = +1
Query: 229 DAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSD 408
+ + S SS + AKM +R+A YNM H NRGMA+IFNHEHFE+ LKSR GTNVD +
Sbjct: 61 NGYSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFEVPTLKSRAGTNVDCE 120
Query: 409 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 588
+L++VL+ L F VTV + R +DI R I+ + +H+D+DC+LVA+LSHGE+G +YAKDT
Sbjct: 121 NLTRVLKQLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKDT 180
Query: 589 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
YK DN+W +FTA+ CP+LAGKPKLFFIQACQG
Sbjct: 181 QYKLDNIWSFFTANHCPSLAGKPKLFFIQACQG 213
Score = 47.2 bits (107), Expect = 6e-04
Identities = 20/34 (58%), Positives = 26/34 (76%), Gaps = 2/34 (5%)
Frame = +2
Query: 683 KGDKLDGGITL--SNTETDGXXXXXYRIPIHADF 778
+GD+LDGG+T+ S TETDG Y+IP+HADF
Sbjct: 212 QGDRLDGGVTMQRSQTETDGDSSMSYKIPVHADF 245
>UniRef50_UPI00015B4D75 Cluster: PREDICTED: similar to CG7788-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG7788-PA - Nasonia vitripennis
Length = 456
Score = 151 bits (366), Expect = 2e-35
Identities = 64/128 (50%), Positives = 92/128 (71%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y + + RG+A+IFNHE FE + SRTGTNVD ++L+ L+ GF V H+L + I+
Sbjct: 211 YENSCSKRGLALIFNHEFFEDDAINSRTGTNVDCENLASTLKSFGFEVRHFHDLTYQCIS 270
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKL 663
Y+ ++++MDH+ +DCL+V VLSHG+LG LYA D Y +++W FT+ CP+L GKP+L
Sbjct: 271 NYLGEVAKMDHSQHDCLVVVVLSHGDLGELYAHDRKYNAESIWSSFTSSNCPSLEGKPRL 330
Query: 664 FFIQACQG 687
FFIQAC+G
Sbjct: 331 FFIQACRG 338
>UniRef50_Q7Q1E0 Cluster: ENSANGP00000015118; n=2; Culicidae|Rep:
ENSANGP00000015118 - Anopheles gambiae str. PEST
Length = 294
Score = 142 bits (345), Expect = 8e-33
Identities = 65/138 (47%), Positives = 92/138 (66%), Gaps = 3/138 (2%)
Frame = +1
Query: 283 VERYAHYYNMNHNNRGMAIIFNHEHFEIHN--LKSRTGTNVDSDSLSKVLRGLGFSVTVL 456
+ERYA YY MNH RGMA+IF+H + + N L R G+ +D L + L F V V
Sbjct: 47 IERYAAYYPMNHKRRGMALIFSHNKYNVRNVSLPVREGSAIDCKRLKETLELFRFDVKVY 106
Query: 457 HNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYYFTADK 633
+ + E+I I ++S MDH+D+DC LVA+L+HGE G ++YA D Y+ +W +FTAD
Sbjct: 107 PDFKLEEIKSVIGKVSSMDHSDSDCFLVAILTHGEDGGIVYAYDQPYELSLIWSFFTADN 166
Query: 634 CPTLAGKPKLFFIQACQG 687
CP+LAG+PK+F +QAC+G
Sbjct: 167 CPSLAGRPKIFVVQACRG 184
>UniRef50_UPI00015B57EE Cluster: PREDICTED: similar to
ENSANGP00000010319; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010319 - Nasonia
vitripennis
Length = 379
Score = 140 bits (338), Expect = 6e-32
Identities = 64/150 (42%), Positives = 97/150 (64%), Gaps = 1/150 (0%)
Frame = +1
Query: 241 SHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSK 420
++ +S A+M ++ A YNM H NRG +IFNHE F+ ++R G++VD+ + +
Sbjct: 112 NYSTSPAEARARMSAQKDADRYNMEHRNRGKCVIFNHETFDT-GFETREGSSVDARRIEQ 170
Query: 421 VLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYK 597
+ LGF+V + + + + ++SE DH+DNDCL + VL+HG + ++ AKD YK
Sbjct: 171 TFQQLGFTVEICDDYEHSGVMNKLNELSEEDHSDNDCLCIFVLTHGLKNDLICAKDVVYK 230
Query: 598 PDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+N+W FTADKC +LAGKPKLFF QAC+G
Sbjct: 231 LENVWKPFTADKCSSLAGKPKLFFFQACRG 260
Score = 33.9 bits (74), Expect = 5.8
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Frame = +2
Query: 671 FKLAKGDKLDGGITL---SNTETDGXXXXXYRIPIHADF 778
F+ +GD LDGGI + TETD Y+IP +ADF
Sbjct: 255 FQACRGDNLDGGIKMMRSGTTETDS-SSASYQIPTYADF 292
>UniRef50_UPI0000E49D20 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 329
Score = 139 bits (337), Expect = 8e-32
Identities = 63/130 (48%), Positives = 87/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAED 477
YY+MNH NRGMA+IFNHE+F+ + R GTN D ++L L LGF V V + A +
Sbjct: 73 YYDMNHKNRGMAVIFNHENFDWKTGMNQRVGTNHDVENLKLHLGRLGFKVLVFQDASASE 132
Query: 478 INRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKP 657
+ R ++ S+ DHTD+DC + L+HG+ G+LYA+D+ L+ +F +KCPTL GKP
Sbjct: 133 LRRNLELASKADHTDSDCFMCVFLTHGDDGILYARDSTLDLQELFEFFRGEKCPTLIGKP 192
Query: 658 KLFFIQACQG 687
KLF IQAC+G
Sbjct: 193 KLFLIQACRG 202
>UniRef50_Q7Q803 Cluster: ENSANGP00000021367; n=6; Anopheles gambiae
str. PEST|Rep: ENSANGP00000021367 - Anopheles gambiae
str. PEST
Length = 320
Score = 133 bits (322), Expect = 5e-30
Identities = 60/129 (46%), Positives = 87/129 (67%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
+YNM+HN RG+A +FNH F +H R GT+ D D++ +VL L F V V +L ++I
Sbjct: 56 HYNMSHNRRGVAAVFNHRKF-LH-ASERKGTDADCDNIRQVLIYLQFEVRVYDDLTRKEI 113
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+ + ++E DH ++DCLLV +++HG+ +L+AKD + D LW F D CP+L GKPK
Sbjct: 114 KQVLDDLAEEDHKNSDCLLVVIMTHGDDDVLHAKDGTFNVDRLWENFIGDSCPSLLGKPK 173
Query: 661 LFFIQACQG 687
LFFIQAC+G
Sbjct: 174 LFFIQACRG 182
>UniRef50_Q17FE3 Cluster: Caspase-1; n=3; Endopterygota|Rep:
Caspase-1 - Aedes aegypti (Yellowfever mosquito)
Length = 293
Score = 133 bits (321), Expect = 7e-30
Identities = 61/153 (39%), Positives = 93/153 (60%), Gaps = 2/153 (1%)
Frame = +1
Query: 235 WGSHGSSQGRRYAKMPVERYA--HYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSD 408
+GS + + + V R A YY+ + RG+A++F H +F + + R G + D D
Sbjct: 12 FGSRTNESSKSIKEALVSRAALDEYYDTTNKRRGIALVFCHMNFSV--MAKRNGADKDRD 69
Query: 409 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 588
+ L GL F V V +L +++ ++ +S DH+DNDCL+V ++SHGE G+LYA+D
Sbjct: 70 DICNTLYGLDFDVRVFDDLSRKEVLDRLKDVSREDHSDNDCLVVVMMSHGEQGVLYARDN 129
Query: 589 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
Y D+LW F + CP+L GKPK+FFIQAC+G
Sbjct: 130 KYNVDSLWKNFVGNACPSLIGKPKMFFIQACRG 162
>UniRef50_Q7Q802 Cluster: ENSANGP00000021365; n=4; Cellia|Rep:
ENSANGP00000021365 - Anopheles gambiae str. PEST
Length = 296
Score = 127 bits (306), Expect = 5e-28
Identities = 59/128 (46%), Positives = 83/128 (64%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y+ NH RGMAII NHE+FE+ + R GTN D D+ + VL + F V V ++L +++
Sbjct: 50 YDTNHRRRGMAIILNHENFEL--MSKREGTNRDRDAATAVLTSMQFDVRVYNDLGRDELF 107
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKL 663
+ ++ DH+D DCLLV +++HG+ +LYA D Y D LW F + C TL GKPKL
Sbjct: 108 CVLLALASEDHSDCDCLLVMLMTHGDDDVLYAYDGPYSVDKLWESFMGNACTTLLGKPKL 167
Query: 664 FFIQACQG 687
FF+QAC+G
Sbjct: 168 FFVQACRG 175
>UniRef50_P55212 Cluster: Caspase-6 precursor (EC 3.4.22.59)
(CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6
subunit p18; Caspase-6 subunit p11]; n=35;
Euteleostomi|Rep: Caspase-6 precursor (EC 3.4.22.59)
(CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6
subunit p18; Caspase-6 subunit p11] - Homo sapiens
(Human)
Length = 293
Score = 120 bits (289), Expect = 5e-26
Identities = 61/153 (39%), Positives = 85/153 (55%), Gaps = 1/153 (0%)
Frame = +1
Query: 232 AWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSD 408
A G ++ + K + A Y M+H RG+A+IFNHE F H L R GT D D
Sbjct: 13 AGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRD 72
Query: 409 SLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT 588
+L++ LGF V ++L+AE++ I ++S + H D DC + LSHGE +YA D
Sbjct: 73 NLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDA 132
Query: 589 HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+ L F DKC +L GKPK+F IQAC+G
Sbjct: 133 KIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRG 165
>UniRef50_Q9NHF9 Cluster: Caspase 6-like protein BG2; n=3;
Sophophora|Rep: Caspase 6-like protein BG2 - Drosophila
melanogaster (Fruit fly)
Length = 308
Score = 119 bits (286), Expect = 1e-25
Identities = 53/120 (44%), Positives = 74/120 (61%)
Frame = +1
Query: 328 GMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISE 507
G+A+I NH+ ++ K R GT D D + L+G GF V +L +IN +++++
Sbjct: 56 GIALILNHK--DVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAR 113
Query: 508 MDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
DH+ NDC ++AV+SHG G +YAKD Y + LW F D C TL KPKLFFIQAC+G
Sbjct: 114 EDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRG 173
>UniRef50_UPI0000519DFF Cluster: PREDICTED: similar to Caspase
precursor (drICE); n=1; Apis mellifera|Rep: PREDICTED:
similar to Caspase precursor (drICE) - Apis mellifera
Length = 280
Score = 116 bits (279), Expect = 8e-25
Identities = 54/143 (37%), Positives = 81/143 (56%), Gaps = 1/143 (0%)
Frame = +1
Query: 262 RRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 441
+++AK + + Y+M RG +IFNHE FE + R GTN D ++++ LGF
Sbjct: 22 KKFAKFVTPKDSPIYSMTQKKRGKCVIFNHEKFENNRESQRNGTNYDEKAINETFSTLGF 81
Query: 442 SVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYY 618
V + +L+ I I + +H D DC+ +L+HG++G + A D Y +W
Sbjct: 82 EVKIYKDLKFNKIIEVITSLQNENHDDCDCICFFILTHGKIGDNVSAYDISYPVQMIWQP 141
Query: 619 FTADKCPTLAGKPKLFFIQACQG 687
F +D C +LAGKPKLFFIQAC+G
Sbjct: 142 FNSDNCISLAGKPKLFFIQACRG 164
>UniRef50_UPI0000F21D96 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
protein, partial - Danio rerio
Length = 170
Score = 114 bits (274), Expect = 3e-24
Identities = 54/128 (42%), Positives = 75/128 (58%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y+M H RGMA+IFN + F + LK+R GT+ D DSL L F V ++ + +
Sbjct: 18 YDMKHAKRGMALIFNQKDFSLLGLKTRKGTDKDRDSLVSRFEELDFEVKAYNDYSRDKVL 77
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKL 663
R I++++ DH D DC + LSHGE G +YA+D K + F DKC +L GKPK+
Sbjct: 78 REIKEVAAADHVDADCFVCIFLSHGEDGHVYARDKKIKIPEITDLFKGDKCRSLVGKPKI 137
Query: 664 FFIQACQG 687
F QAC+G
Sbjct: 138 FIWQACRG 145
>UniRef50_Q2TM51 Cluster: Caspase; n=3; Penaeidae|Rep: Caspase -
Fenneropenaeus merguiensis (Banana prawn) (Penaeus
merguiensis)
Length = 320
Score = 113 bits (272), Expect = 6e-24
Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 6/149 (4%)
Frame = +1
Query: 259 GRRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLG 438
GR A V+ + Y MN+ RG A+IF H F+ +L+ R D++ S + LG
Sbjct: 46 GRTTAYTVVDGLSERYPMNNRPRGAALIFAHSEFKNESLRPRPSAAHDAEIASDAFKALG 105
Query: 439 FSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGE------LGMLYAKDTHYKP 600
F V NL +++ + + ++S+ DH+ +D L++ +SHGE + ++AKD
Sbjct: 106 FLPEVFSNLTKDELEKTLHEVSKRDHSGSDALVIVFMSHGEVKPRNNMEFVWAKDDKIPT 165
Query: 601 DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
LW FTA++C +LAGKPKL+FIQAC+G
Sbjct: 166 KELWINFTAERCASLAGKPKLYFIQACRG 194
>UniRef50_Q92851 Cluster: Caspase-10 precursor (EC 3.4.22.63)
(CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
protease Mch-4) (FAS-associated death domain protein
interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
Caspase-10 subunit p23/17; Caspase-10 subunit p12]; n=9;
Eutheria|Rep: Caspase-10 precursor (EC 3.4.22.63)
(CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
protease Mch-4) (FAS-associated death domain protein
interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
Caspase-10 subunit p23/17; Caspase-10 subunit p12] -
Homo sapiens (Human)
Length = 521
Score = 111 bits (268), Expect = 2e-23
Identities = 65/175 (37%), Positives = 96/175 (54%), Gaps = 2/175 (1%)
Frame = +1
Query: 169 EKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFN 348
+ K+ GS + NG G G+S ++ +R A Y MN N+RG+ +I N
Sbjct: 233 QNKHAGSNGNRATNGAPSLVSR-GMQGASANTLNSETSTKRAA-VYRMNRNHRGLCVIVN 290
Query: 349 HEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDN 525
+ F +LK R GT+ D++ LS V + LGF+V + +N+ ++ +Q Q H D
Sbjct: 291 NHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADG 348
Query: 526 DCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
DC + +L+HG G +Y+ D P + +FTA +CP LA KPKLFFIQACQG
Sbjct: 349 DCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQG 403
>UniRef50_UPI0000F2DFE7 Cluster: PREDICTED: similar to apoptotic
cysteine protease proMch4; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to apoptotic cysteine
protease proMch4 - Monodelphis domestica
Length = 452
Score = 111 bits (267), Expect = 2e-23
Identities = 57/136 (41%), Positives = 80/136 (58%), Gaps = 2/136 (1%)
Frame = +1
Query: 286 ERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNL 465
E+ A +Y M+H++RG IIFN+ FE +K R G+ D+D L V LGF+V + N
Sbjct: 200 EQEAKFYRMDHSHRGHCIIFNN--FEFQTMKRRRGSCKDADELKSVFEWLGFTVKIHPNT 257
Query: 466 RAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCP 639
++ +QQ S +H ++DC + VL+HGE G +++ D L YF A +CP
Sbjct: 258 EKREMEDILQQCSTSPEHRESDCFVCCVLTHGESGSVFSSDEEKIAIRELTSYFKAHRCP 317
Query: 640 TLAGKPKLFFIQACQG 687
LA KPKLFF QACQG
Sbjct: 318 GLANKPKLFFFQACQG 333
>UniRef50_Q8ITP2 Cluster: AmphiCASP-6; n=2; Chordata|Rep:
AmphiCASP-6 - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 400
Score = 111 bits (267), Expect = 2e-23
Identities = 54/130 (41%), Positives = 79/130 (60%), Gaps = 2/130 (1%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
YNMNH RG+ ++F++E F + R G++VD+ +L + GLGFSV VL + +I
Sbjct: 143 YNMNHPQRGLCLVFDNEEFHWTTKMNRRRGSHVDAGNLKVMFEGLGFSVEVLKDKEITEI 202
Query: 481 NRYIQQIS-EMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKP 657
+ + + + DH+ +DC + LSHGE GM+Y + L F AD+C +L GKP
Sbjct: 203 RQILHSAALKYDHSQSDCFVCVFLSHGEDGMIYGYNGTVPIKELTDMFRADRCTSLKGKP 262
Query: 658 KLFFIQACQG 687
KLFFIQAC+G
Sbjct: 263 KLFFIQACRG 272
>UniRef50_Q69HP8 Cluster: Caspase-1-like; n=1; Ciona
intestinalis|Rep: Caspase-1-like - Ciona intestinalis
(Transparent sea squirt)
Length = 254
Score = 111 bits (266), Expect = 3e-23
Identities = 54/129 (41%), Positives = 83/129 (64%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
YNM+ RG+ +IF+ E+F+ + L+ R G+ +D L + LGF+ V H+ +D+
Sbjct: 57 YNMSFPKRGIFLIFDQENFD-YGLQQRVGSKLDRIVLEETAIKLGFTPNVCHDYTKDDVY 115
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+++IS+M+H+ DC A+L+HGE M+YAKD K L +A +CP+LAGKPK
Sbjct: 116 AELRKISQMNHSQYDCFACAILTHGEEDEMVYAKDDSMKLKTLISRVSATECPSLAGKPK 175
Query: 661 LFFIQACQG 687
LFF+QAC+G
Sbjct: 176 LFFVQACRG 184
>UniRef50_Q92851-2 Cluster: Isoform B of Q92851 ; n=9; Mammalia|Rep:
Isoform B of Q92851 - Homo sapiens (Human)
Length = 479
Score = 108 bits (259), Expect = 2e-22
Identities = 56/133 (42%), Positives = 80/133 (60%), Gaps = 2/133 (1%)
Frame = +1
Query: 295 AHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 474
A Y MN N+RG+ +I N+ F +LK R GT+ D++ LS V + LGF+V + +N+
Sbjct: 230 AAVYRMNRNHRGLCVIVNNHSFT--SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKV 287
Query: 475 DINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLA 648
++ +Q Q H D DC + +L+HG G +Y+ D P + +FTA +CP LA
Sbjct: 288 EMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLA 347
Query: 649 GKPKLFFIQACQG 687
KPKLFFIQACQG
Sbjct: 348 EKPKLFFIQACQG 360
>UniRef50_A1L2P4 Cluster: LOC100036910 protein; n=1; Xenopus
laevis|Rep: LOC100036910 protein - Xenopus laevis
(African clawed frog)
Length = 235
Score = 105 bits (252), Expect = 2e-21
Identities = 52/136 (38%), Positives = 81/136 (59%), Gaps = 3/136 (2%)
Frame = +1
Query: 289 RYAHY--YNMNHNNRGMAIIFNHEHFEIH-NLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 459
++AH Y ++ G+ +I N+++F ++ R GT+VD+ L + LG+ V VL+
Sbjct: 41 KFAHLFKYRTDYPEMGVCLIINNKNFHSSTSMTVRNGTDVDARRLHETFTSLGYKVKVLN 100
Query: 460 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCP 639
+ R DI +++++SE DH+ A+LSHGE G++Y D NL F D+C
Sbjct: 101 DQRCNDIFGHLKKMSEEDHSKRSSFACAILSHGEDGLIYGVDGPIPVKNLTDLFRGDRCK 160
Query: 640 TLAGKPKLFFIQACQG 687
TL GKPK+FFIQAC+G
Sbjct: 161 TLVGKPKIFFIQACRG 176
>UniRef50_P55210 Cluster: Caspase-7 precursor (EC 3.4.22.60)
(CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3)
(Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7
subunit p20; Caspase-7 subunit p11]; n=58;
Euteleostomi|Rep: Caspase-7 precursor (EC 3.4.22.60)
(CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3)
(Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7
subunit p20; Caspase-7 subunit p11] - Homo sapiens
(Human)
Length = 303
Score = 105 bits (252), Expect = 2e-21
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 1/131 (0%)
Frame = +1
Query: 298 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 474
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 475 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGK 654
+ +++ SE DHT+ C +LSHGE ++Y KD +L +F D+C TL K
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEK 177
Query: 655 PKLFFIQACQG 687
PKLFFIQAC+G
Sbjct: 178 PKLFFIQACRG 188
>UniRef50_UPI0000F2097E Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 266
Score = 105 bits (251), Expect = 2e-21
Identities = 51/125 (40%), Positives = 71/125 (56%), Gaps = 1/125 (0%)
Frame = +1
Query: 316 HNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ 495
H N G +I ++EHF R G +VD LS + LGF V V +NL A + ++
Sbjct: 24 HKNIGKCLIISNEHFPDSPRLYRKGNSVDERRLSSTFKSLGFHVKVENNLSANQMIDALR 83
Query: 496 QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFI 672
+SE DHTDN C + ++SHGE G + D + P L T+D CP+L KPK+FF+
Sbjct: 84 TVSEEDHTDNSCFVCVLMSHGEEGTILGSDERWIPVKTLTSLLTSDLCPSLRDKPKIFFL 143
Query: 673 QACQG 687
QAC+G
Sbjct: 144 QACRG 148
>UniRef50_UPI0001554FA5 Cluster: PREDICTED: similar to initiator
caspase, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to initiator caspase, partial -
Ornithorhynchus anatinus
Length = 480
Score = 104 bits (250), Expect = 3e-21
Identities = 57/143 (39%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
Frame = +1
Query: 262 RRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 441
RR P Y MNH G +I N+ F+ + +R G + D+ +L KV L F
Sbjct: 215 RRAVLSPAVGIMAPYKMNHLPHGFCVIINNSEFQ-NPQNTRRGADKDAAALDKVFSWLQF 273
Query: 442 SVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYY 618
V +NL+ E I+R ++ SE DHTD DC + +LSHG+ G + D P L
Sbjct: 274 KVEHHNNLKGEAISRVLRAYSERDHTDQDCFICCLLSHGQKGEILGTDWEPVPLRALLGL 333
Query: 619 FTADKCPTLAGKPKLFFIQACQG 687
FT+ C TLA KPK+FF+QACQG
Sbjct: 334 FTSSACRTLATKPKIFFVQACQG 356
>UniRef50_UPI0000586459 Cluster: PREDICTED: similar to caspase-3,
partial; n=10; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to caspase-3, partial -
Strongylocentrotus purpuratus
Length = 437
Score = 103 bits (248), Expect = 5e-21
Identities = 50/129 (38%), Positives = 81/129 (62%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M RG+A+I N+++F+ + R GT++D +L + L F V V ++L+ DI
Sbjct: 157 YKMKSKPRGIALIINNKNFK--TMPPRRGTDIDCRNLENIFTQLDFDVVVHNDLKKRDIQ 214
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 660
+ I+Q+ + +H+ DC + A+L+HGE G + D K +++ F +D+CPTL GKPK
Sbjct: 215 QKIEQVRKHNHSQFDCFIFAILTHGEEGSVCGTDGCLVKIEDIVGPFCSDRCPTLNGKPK 274
Query: 661 LFFIQACQG 687
LFF+QAC+G
Sbjct: 275 LFFLQACRG 283
>UniRef50_Q7QKT2 Cluster: ENSANGP00000015505; n=3; Anopheles gambiae
str. PEST|Rep: ENSANGP00000015505 - Anopheles gambiae
str. PEST
Length = 263
Score = 103 bits (247), Expect = 6e-21
Identities = 50/130 (38%), Positives = 74/130 (56%)
Frame = +1
Query: 298 HYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAED 477
H YNM H RG+A++ N N + R G+ D +L VL L F V +L + +
Sbjct: 25 HSYNMAHPKRGIAVVIN-------NNRDRKGSEKDVKALQAVLSHLQFDVRLLSDKTTVE 77
Query: 478 INRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKP 657
I ++++S+ DHT+NDCL + ++HG + D + D LW F +KCP+L GKP
Sbjct: 78 IRHALKEVSKEDHTNNDCLAIIAMAHGYNDRIKFDDDYLHIDELWTNFVGNKCPSLIGKP 137
Query: 658 KLFFIQACQG 687
KL FIQ+C+G
Sbjct: 138 KLVFIQSCRG 147
>UniRef50_UPI0000E48555 Cluster: PREDICTED: similar to Lice2
cysteine protease, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Lice2 cysteine
protease, partial - Strongylocentrotus purpuratus
Length = 388
Score = 102 bits (244), Expect = 1e-20
Identities = 50/129 (38%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y M++ RG A+I N F+ + + +R GT+ D + L +V LGF +L +
Sbjct: 138 YKMDYPCRGKAVIVNQTRFDPMTGMSNREGTDPDIEGLDRVFSNLGFRTEAHSDLTIAEF 197
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+ ++++S D +++DCLL +SHGE G+LY +D D L CPTL GKPK
Sbjct: 198 RKLLKELSIEDFSNDDCLLFIAMSHGEEGVLYCRDGTVAVDELVCRLKGIMCPTLVGKPK 257
Query: 661 LFFIQACQG 687
LFFIQAC+G
Sbjct: 258 LFFIQACRG 266
>UniRef50_Q98UI8 Cluster: Caspase-3; n=4; Chordata|Rep: Caspase-3 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 282
Score = 100 bits (240), Expect = 4e-20
Identities = 49/135 (36%), Positives = 80/135 (59%), Gaps = 1/135 (0%)
Frame = +1
Query: 286 ERYAHYYNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 462
+ +A Y++N+ N G II N+++F+ + R GT+VD+ ++ V R LG+ V V ++
Sbjct: 34 QSHAFRYSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYND 93
Query: 463 LRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPT 642
I + + ++ DH+ L+ +LSHG+ G+ + DT +L F D+CP+
Sbjct: 94 QTVAQIMQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPS 153
Query: 643 LAGKPKLFFIQACQG 687
L GKPKLFFIQAC+G
Sbjct: 154 LVGKPKLFFIQACRG 168
>UniRef50_Q56VC9 Cluster: Caspase-8; n=3; Euteleostei|Rep: Caspase-8
- Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 481
Score = 99.5 bits (237), Expect = 1e-19
Identities = 54/131 (41%), Positives = 76/131 (58%), Gaps = 2/131 (1%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHE-HFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAED 477
YY+ H RG+ +IFN++ F NL R GT D SL+ + GF V V +NL A+
Sbjct: 233 YYSFTHEPRGLCVIFNNKLFFPESNLGERGGTEKDEKSLNNLFHRFGFEVVVHNNLTADL 292
Query: 478 INRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD-THYKPDNLWYYFTADKCPTLAGK 654
I I ++ + + + +D L+V VLSHG+ G +Y D + L F + + P+L GK
Sbjct: 293 IESEITKLGQRNFSHDDALVVCVLSHGDNGCVYGIDGKKVQLRALTLPFPSYRAPSLIGK 352
Query: 655 PKLFFIQACQG 687
PKLFFIQACQG
Sbjct: 353 PKLFFIQACQG 363
>UniRef50_Q14790 Cluster: Caspase-8 precursor (EC 3.4.22.61)
(CASP-8) (ICE-like apoptotic protease 5)
(MORT1-associated CED-3 homolog) (MACH) (FADD-homologous
ICE/CED-3-like protease) (FADD-like ICE) (FLICE)
(Apoptotic cysteine protease) (Apoptotic protease Mch-5)
(CAP4) [Contains: Caspase-8 subunit p18; Caspase-8
subunit p10]; n=35; Amniota|Rep: Caspase-8 precursor (EC
3.4.22.61) (CASP-8) (ICE-like apoptotic protease 5)
(MORT1-associated CED-3 homolog) (MACH) (FADD-homologous
ICE/CED-3-like protease) (FADD-like ICE) (FLICE)
(Apoptotic cysteine protease) (Apoptotic protease Mch-5)
(CAP4) [Contains: Caspase-8 subunit p18; Caspase-8
subunit p10] - Homo sapiens (Human)
Length = 479
Score = 99.1 bits (236), Expect = 1e-19
Identities = 50/137 (36%), Positives = 76/137 (55%), Gaps = 9/137 (6%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHF--------EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 459
Y M RG +I N+ +F ++H+++ R GT++D+ +L+ L F +
Sbjct: 226 YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHD 285
Query: 460 NLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKC 636
+ E I ++ MDH++ DC + +LSHG+ G++Y D P L FT KC
Sbjct: 286 DCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKC 345
Query: 637 PTLAGKPKLFFIQACQG 687
P+LAGKPK+FFIQACQG
Sbjct: 346 PSLAGKPKVFFIQACQG 362
>UniRef50_Q5DD62 Cluster: SJCHGC00800 protein; n=3; Schistosoma
japonicum|Rep: SJCHGC00800 protein - Schistosoma
japonicum (Blood fluke)
Length = 288
Score = 98.7 bits (235), Expect = 2e-19
Identities = 42/122 (34%), Positives = 73/122 (59%), Gaps = 1/122 (0%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIH-NLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQI 501
RG ++ N F+ N R GT++D+D + +V R L + VT + N+ + +++ + +
Sbjct: 45 RGECLLINQRDFDPSTNQSKRNGTDIDADRIERVFRSLNYKVTRILNITKKALDQTLIEA 104
Query: 502 SEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQAC 681
S+ DH+ D + +L+HG+ ++YA D + + +F D+CP+L GKPKLFF QAC
Sbjct: 105 SQKDHSSYDSFVFVMLTHGDKDVVYASDDEVQTSYIMSFFRGDRCPSLIGKPKLFFFQAC 164
Query: 682 QG 687
+G
Sbjct: 165 RG 166
>UniRef50_Q9IB62 Cluster: Caspase-10; n=5; Xenopus|Rep: Caspase-10 -
Xenopus laevis (African clawed frog)
Length = 520
Score = 98.3 bits (234), Expect = 2e-19
Identities = 50/129 (38%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y+MNH +RG +I ++ F K R G++ D+ +LS V LG V ++ NL E I
Sbjct: 268 YHMNHKHRGYCLIIDNSIFM--KGKRREGSDKDAGALSDVFSWLGLEVEIVKNLGTEQIR 325
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+++ DH++ DC + +L+HGE G ++ + D + YFTA C +L KPK
Sbjct: 326 GCLKRFKSKDHSERDCFVCCILTHGESGTVMGSDDKEVSIREVMSYFTATSCISLTLKPK 385
Query: 661 LFFIQACQG 687
LFFIQACQG
Sbjct: 386 LFFIQACQG 394
>UniRef50_Q4SC67 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=2; Deuterostomia|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 445
Score = 98.3 bits (234), Expect = 2e-19
Identities = 54/137 (39%), Positives = 77/137 (56%), Gaps = 9/137 (6%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y M N G +I N+ FE + L +R G+NVD D L + + L F+V V NL+ I
Sbjct: 149 YRMEANPLGHCLIINNVEFEPKSGLSNRNGSNVDCDRLERRFKALNFTVKVKTNLKQRQI 208
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHG-EL------GMLYAKDTHYKP-DNLWYYFTADKC 636
+ + +S++DH+ DC +V +LSHG E+ G +Y D + P ++ Y C
Sbjct: 209 RQELSALSKVDHSQYDCCVVVILSHGTEVSHSRFPGAVYGVDGQFVPVQHIATYLNGQYC 268
Query: 637 PTLAGKPKLFFIQACQG 687
P+L GKPKLFFIQAC G
Sbjct: 269 PSLQGKPKLFFIQACGG 285
>UniRef50_UPI0000E472FD Cluster: PREDICTED: similar to caspase 8;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to caspase 8 - Strongylocentrotus purpuratus
Length = 790
Score = 96.7 bits (230), Expect = 7e-19
Identities = 52/130 (40%), Positives = 72/130 (55%), Gaps = 2/130 (1%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRG-LGFSVTVLHNLRAEDI 480
Y M+ RG+ IIFN E+F NL R GT D ++L + L F + V + A+
Sbjct: 428 YKMDRLPRGLCIIFNAENFTRKNLHKRDGTEKDVEALLNTFQNRLKFKIRVEQDPTADKY 487
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKP 657
+ +Q+I+ DH++ DC + +LSHG G +Y D P D L F + P+L KP
Sbjct: 488 LKCLQEIARSDHSEYDCFVCIILSHGCKGHVYGTDGRLMPIDALTGLFRGEYVPSLVNKP 547
Query: 658 KLFFIQACQG 687
KLFFIQACQG
Sbjct: 548 KLFFIQACQG 557
Score = 38.7 bits (86), Expect = 0.20
Identities = 16/23 (69%), Positives = 17/23 (73%)
Frame = +1
Query: 619 FTADKCPTLAGKPKLFFIQACQG 687
F D P+L KPKLFFIQACQG
Sbjct: 663 FRGDYVPSLVNKPKLFFIQACQG 685
>UniRef50_Q8I6Y2 Cluster: Caspase-3; n=2; Geodia cydonium|Rep:
Caspase-3 - Geodia cydonium (Sponge)
Length = 426
Score = 96.3 bits (229), Expect = 1e-18
Identities = 48/129 (37%), Positives = 76/129 (58%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M+ RGMA+I N+ +F +K R GT+ D+++L + LG + NL + +
Sbjct: 150 YKMSSRPRGMALIINNRNFTC-GMKERVGTDKDAENLYGLFNWLGMATIRKDNLTGKAMT 208
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPK 660
R + ++ DH+ DC++VA+L+HG G LY+ D P ++L YF P+L GKPK
Sbjct: 209 REFEDLARRDHSAYDCVVVAILTHGISGRLYSTDGDLIPVEDLTKYFDGVNRPSLIGKPK 268
Query: 661 LFFIQACQG 687
+F +QAC+G
Sbjct: 269 VFVVQACRG 277
>UniRef50_Q4JQQ0 Cluster: Initiator caspase; n=2; Gallus gallus|Rep:
Initiator caspase - Gallus gallus (Chicken)
Length = 464
Score = 95.9 bits (228), Expect = 1e-18
Identities = 50/129 (38%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M +N G +I N+ F+ N ++R GT D +L +V + L F +L A+ I
Sbjct: 216 YKMENNPHGYCVILNNYRFKNPN-ETRKGTVEDGKALKRVFKWLQFDTIEYMDLEAKQIF 274
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPK 660
+ + S+ DH++ DC + +LSHGE G + D +L F+ CP+LAGKPK
Sbjct: 275 AKVNEYSKKDHSNMDCFVCFILSHGEKGKIKGVDNELVNIKDLLSCFSGSNCPSLAGKPK 334
Query: 661 LFFIQACQG 687
LFFIQACQG
Sbjct: 335 LFFIQACQG 343
>UniRef50_Q3HL92 Cluster: Caspase-like protein; n=6; Eumetazoa|Rep:
Caspase-like protein - Aiptasia pallida (Sea anemone)
Length = 415
Score = 95.9 bits (228), Expect = 1e-18
Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 5/178 (2%)
Frame = +1
Query: 169 EKKNNGSGTEQRKNGNEDEGDAWGS-HGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIF 345
EK S +N ED D S GS R P++ + Y M+ RG+A+I
Sbjct: 125 EKTPIASTDGASENSGEDNPDGGLSIFGSGSTRTRTSEPIDTRS-MYKMDKTPRGVAVII 183
Query: 346 NHEHF----EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMD 513
N++ F +H R GT+VD D+L KV + LGF+ V ++ +I + + ++ D
Sbjct: 184 NNKSFLPASGMHRYP-RNGTDVDRDALDKVFQKLGFNTLVYNDQSVYEIQKIFKSLAARD 242
Query: 514 HTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
++ + L+V++L+HGE G+LYA D + ++ +F K L GKPK+F QACQG
Sbjct: 243 YSKENALIVSILTHGEEGILYATDGTIQIRDMMRWF---KGTNLVGKPKIFIFQACQG 297
>UniRef50_A7SPA7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 242
Score = 95.5 bits (227), Expect = 2e-18
Identities = 45/129 (34%), Positives = 73/129 (56%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M RG+ +I +++HF+ L+ R G D ++L + L F V + + A ++
Sbjct: 4 YPMTSRPRGICLIISNQHFDKPELRKRDGNEQDVENLKRTFENLHFVVEIRQDKTASEMY 63
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPK 660
++ S +DH+ D + +LSHG LG +Y D++ + + + F + CPTLA KPK
Sbjct: 64 TIAREFSSIDHSAYDLFVCCILSHGMLGSIYGSDSNLIEINEISSQFKGNACPTLAHKPK 123
Query: 661 LFFIQACQG 687
LFFIQAC+G
Sbjct: 124 LFFIQACRG 132
>UniRef50_A2BGE2 Cluster: Novel protein similar to caspase 8; n=4;
Danio rerio|Rep: Novel protein similar to caspase 8 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 366
Score = 95.1 bits (226), Expect = 2e-18
Identities = 51/129 (39%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M N RG+ +IFN+E+F+ ++K R G+ +D+ SL + LGFSV + + +
Sbjct: 123 YEMKSNPRGLCLIFNNENFKDPDMK-RHGSQMDTASLKDLFEWLGFSVEIKQDQTVSAMK 181
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
R +++ SE D DC + VLSHG E G+L + + D++ F C +LAGKPK
Sbjct: 182 RTLKEYSE-DRKHGDCFVCCVLSHGNESGVLGSDEKICPVDDITSPFNGANCSSLAGKPK 240
Query: 661 LFFIQACQG 687
+FFIQAC+G
Sbjct: 241 VFFIQACRG 249
>UniRef50_Q90WU0 Cluster: Caspase 9; n=2; Gallus gallus|Rep: Caspase
9 - Gallus gallus (Chicken)
Length = 403
Score = 94.7 bits (225), Expect = 3e-18
Identities = 51/129 (39%), Positives = 76/129 (58%), Gaps = 9/129 (6%)
Frame = +1
Query: 328 GMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
G +IFN+ F + L +R G+++D + L K R L F V L NL+A++I+ +++++
Sbjct: 148 GHCLIFNNVSFSRDSDLSTRAGSDIDCEKLEKRFRSLCFHVRTLRNLKAQEIDVELRKLA 207
Query: 505 EMDHTDNDCLLVAVLSHG-------ELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPK 660
+DH+ DC LV +LSHG G +Y D P + + YF +CP+L GKPK
Sbjct: 208 RLDHSALDCCLVVILSHGCQTSHIQFPGGIYGTDGKIIPIERIVNYFNGSQCPSLRGKPK 267
Query: 661 LFFIQACQG 687
LFFIQAC G
Sbjct: 268 LFFIQACGG 276
>UniRef50_Q4V923 Cluster: Zgc:101776 protein; n=8;
Clupeocephala|Rep: Zgc:101776 protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 436
Score = 94.7 bits (225), Expect = 3e-18
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 9/137 (6%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y M+ + G+ +I N+ +FE L R G+N+D D L K +GL F VTV NL+++ I
Sbjct: 164 YKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEKRFKGLNFEVTVKRNLKSKRI 223
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGE-------LGMLYAKDTHYKP-DNLWYYFTADKC 636
+ +++ DH+ DC +V +LSHG G ++ D P + Y C
Sbjct: 224 RHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNC 283
Query: 637 PTLAGKPKLFFIQACQG 687
P+L GKPKLFFIQAC G
Sbjct: 284 PSLQGKPKLFFIQACGG 300
>UniRef50_Q0Z855 Cluster: Caspase-2; n=1; Haemaphysalis
longicornis|Rep: Caspase-2 - Haemaphysalis longicornis
(Bush tick)
Length = 340
Score = 94.7 bits (225), Expect = 3e-18
Identities = 50/140 (35%), Positives = 78/140 (55%), Gaps = 3/140 (2%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y+M N RG II N+ F H+L+ R G+ +D D ++ + R L F+V++ NL A++
Sbjct: 17 YSMTRNPRGSCIIVNNADFHDHSLRCREGSQLDVDRMAGLFRQLHFNVSIASNLSAKETK 76
Query: 484 RYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTH--YKPDNLWYYFTADKCPTLAGK 654
++ + + D +CL V ++SHGE G+LY D + +++ F + CP L GK
Sbjct: 77 DLLRGFQKAETQKDAECLAVILMSHGEDGVLYGSDGEKLHLDRDVYQLFDNENCPNLRGK 136
Query: 655 PKLFFIQACQG**VRWWNNI 714
PKLFFI +G W N I
Sbjct: 137 PKLFFIPGSRG--CMWDNGI 154
>UniRef50_Q0WYJ4 Cluster: Caspase 10; n=4; Percomorpha|Rep: Caspase
10 - Paralichthys olivaceus (Japanese flounder)
Length = 494
Score = 93.1 bits (221), Expect = 9e-18
Identities = 52/129 (40%), Positives = 67/129 (51%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M RG+ +I N+ F +LK R GT +D + L V + LGF V V N E +
Sbjct: 242 YPMTEAKRGICLIINNHVFPETSLKPRDGTMIDEECLRDVFKWLGFDVEVHLNCTREKML 301
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPK 660
+ + DH C+ VLSHG G ++ D K ++L A CPTLA KPK
Sbjct: 302 SLLWDLGRRDHRQMSCVACFVLSHGLEGGVHGVDNKIVKINDLMEPLNAHNCPTLAQKPK 361
Query: 661 LFFIQACQG 687
LFFIQACQG
Sbjct: 362 LFFIQACQG 370
>UniRef50_Q6E5N8 Cluster: Caspase 8; n=1; Ictalurus punctatus|Rep:
Caspase 8 - Ictalurus punctatus (Channel catfish)
Length = 366
Score = 91.5 bits (217), Expect = 3e-17
Identities = 47/129 (36%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M+ RG +I N+ +F LK R G+ +D DSL +V + LGF+V V N AE +
Sbjct: 111 YKMSSEPRGFCVIINNVNFA-SPLKERYGSKLDEDSLKEVFQWLGFNVCVHKNQTAEQMK 169
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 660
+++ S+ H D DC + ++SHG ++ D D+++ F+ + CP+L KPK
Sbjct: 170 DLLKKYSQQHH-DGDCFVCCIMSHGSSDGVHGTDGAIASRDDIFGPFSGNSCPSLINKPK 228
Query: 661 LFFIQACQG 687
+F IQAC+G
Sbjct: 229 VFIIQACRG 237
>UniRef50_UPI0000ECB87F Cluster: Caspase-10 precursor (EC 3.4.22.63)
(CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
protease Mch-4) (FAS-associated death domain protein
interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
Caspase-10 subunit p23/17; Caspase-10 subunit p12].;
n=2; Gallus gallus|Rep: Caspase-10 precursor (EC
3.4.22.63) (CASP-10) (ICE-like apoptotic protease 4)
(Apoptotic protease Mch-4) (FAS-associated death domain
protein interleukin-1B-converting enzyme 2) (FLICE2)
[Contains: Caspase-10 subunit p23/17; Caspase-10 subunit
p12]. - Gallus gallus
Length = 537
Score = 91.1 bits (216), Expect = 4e-17
Identities = 51/131 (38%), Positives = 72/131 (54%), Gaps = 3/131 (2%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M+ RG+ ++ N+ F+ L+ R G+ D+ L +V LG V + ++ I
Sbjct: 285 YKMDGPRRGICLVINNVKFD-GVLQERKGSYKDACELERVFTWLGLDVRTYTDQTSDQIK 343
Query: 484 RYIQ--QISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGK 654
+Q Q SE DH + DC + +LSHGE G +Y KD + YFTA +CP L K
Sbjct: 344 ELMQAWQRSE-DHKNRDCFVCCILSHGESGAVYGKDGKLVSIRTIMTYFTAKQCPQLTEK 402
Query: 655 PKLFFIQACQG 687
PKLFF+QACQG
Sbjct: 403 PKLFFVQACQG 413
>UniRef50_UPI0000F2DFE8 Cluster: PREDICTED: similar to initiator
caspase; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to initiator caspase - Monodelphis domestica
Length = 473
Score = 90.6 bits (215), Expect = 5e-17
Identities = 51/130 (39%), Positives = 71/130 (54%), Gaps = 3/130 (2%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M H G +I ++ HF + + R GT D +L KV L F NL A ++
Sbjct: 208 YKMEHVPHGYVVIIDNIHFS-NPVDVRIGTEKDVAALRKVFGRLQFKEKYHSNLDASQLH 266
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP---DNLWYYFTADKCPTLAGK 654
++ S+ D+TD D + +LSHG+ G++ D +KP L YFTA++C TL K
Sbjct: 267 EVMKDYSKRDYTDQDAFICCILSHGKKGVVLGTD--WKPVAIKKLLSYFTANECKTLKDK 324
Query: 655 PKLFFIQACQ 684
PKLFFIQACQ
Sbjct: 325 PKLFFIQACQ 334
>UniRef50_Q2HZ04 Cluster: ICE-5; n=3; Bombyx mori|Rep: ICE-5 -
Bombyx mori (Silk moth)
Length = 312
Score = 89.8 bits (213), Expect = 8e-17
Identities = 50/135 (37%), Positives = 75/135 (55%), Gaps = 6/135 (4%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNH------EHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 462
YYNM+ + IIFNH ++F+ +R GT D SL + GL ++VT +
Sbjct: 42 YYNMSGDK--YLIIFNHYTFKKTKYFQYKQPSTRNGTFEDVKSLKDLFEGLSYNVTTYTD 99
Query: 463 LRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPT 642
L EDI + + + DH+ C++V +L+HG+ G ++A D YK +L + T
Sbjct: 100 LIYEDILNRVAEFCQRDHSKTSCVIVTILTHGDSGEVFAADQPYKISDL-TNMIENAHHT 158
Query: 643 LAGKPKLFFIQACQG 687
L GKPK+FFIQAC+G
Sbjct: 159 LVGKPKIFFIQACRG 173
>UniRef50_P55213 Cluster: Caspase-3 precursor (EC 3.4.22.56)
(CASP-3) (Apopain) (Cysteine protease CPP32) (Yama
protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1)
(LICE) (IRP) [Contains: Caspase-3 subunit p17; Caspase-3
subunit p12]; n=32; Euteleostomi|Rep: Caspase-3
precursor (EC 3.4.22.56) (CASP-3) (Apopain) (Cysteine
protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage
activity 1) (SCA-1) (LICE) (IRP) [Contains: Caspase-3
subunit p17; Caspase-3 subunit p12] - Rattus norvegicus
(Rat)
Length = 277
Score = 88.2 bits (209), Expect = 3e-16
Identities = 42/129 (32%), Positives = 73/129 (56%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y M++ G+ II N+++F + + +R GT+VD+ +L + L + V ++L E+I
Sbjct: 37 YKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEI 96
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+ +S+ DH+ + +LSHG+ G+++ + L +F D C +L GKPK
Sbjct: 97 MELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPK 156
Query: 661 LFFIQACQG 687
LF IQAC+G
Sbjct: 157 LFIIQACRG 165
>UniRef50_Q09HM6 Cluster: Caspase-8; n=1; Molgula tectiformis|Rep:
Caspase-8 - Molgula tectiformis
Length = 700
Score = 87.0 bits (206), Expect = 6e-16
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 1/106 (0%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLS 552
LK+R G+ +D+D++ + G F V ++L+ ++ IQ+ SEMDH+ D + +LS
Sbjct: 456 LKNRAGSKIDADAIEDIFTGFSFKVHRCNDLKHREMQICIQEFSEMDHSKYDSFVCVILS 515
Query: 553 HGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
HG+ ++Y+ D + ++ ++ +FT C TL KPKL FIQAC G
Sbjct: 516 HGKRNIVYSVDGYKFRISDIQSFFTTTTCSTLQDKPKLVFIQACAG 561
>UniRef50_UPI000051A33A Cluster: PREDICTED: similar to CG6597-PA,
isoform A; n=2; Coelomata|Rep: PREDICTED: similar to
CG6597-PA, isoform A - Apis mellifera
Length = 478
Score = 85.8 bits (203), Expect = 1e-15
Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 9/140 (6%)
Frame = +1
Query: 283 VERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSV----- 447
V+ Y M+H RG A+IFN+ + + R T + +LS+ + +GF V
Sbjct: 58 VDPNVEVYKMHHKRRGTALIFNN----VKIYQERNNTEACARNLSQTFQMMGFDVELIVD 113
Query: 448 ----TVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWY 615
++ L++ + +++ DHT+NDCL VAVLS G G L A + Y LW
Sbjct: 114 ATLQVIIEKLKSAKLINPFVKVASQDHTNNDCLAVAVLSTGTSGYLKADNMFYPAQMLWM 173
Query: 616 YFTADKCPTLAGKPKLFFIQ 675
F D CP L KPK+FF+Q
Sbjct: 174 PFLPDSCPGLIDKPKIFFLQ 193
>UniRef50_Q9I8J3 Cluster: Caspase-8; n=11; Danio rerio|Rep:
Caspase-8 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 476
Score = 84.2 bits (199), Expect = 4e-15
Identities = 50/131 (38%), Positives = 69/131 (52%), Gaps = 2/131 (1%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAED 477
YY + G +I N+ +F E NL RTGT++D D L+K+ + F + V ++L A
Sbjct: 229 YYILTQRPLGYCLIINNYNFLESTNLLKRTGTDMDKDRLAKLFSRMHFQIEVRNDLEAWA 288
Query: 478 INRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNL-WYYFTADKCPTLAGK 654
I I+Q + +H + +LSHGE G + D KP + C TLA K
Sbjct: 289 IKDEIKQFANRNHASMGAFVCCILSHGEKGTVLGTDG--KPVEIREVTLPFAGCRTLASK 346
Query: 655 PKLFFIQACQG 687
PKLFFIQACQG
Sbjct: 347 PKLFFIQACQG 357
>UniRef50_Q4RG79 Cluster: Chromosome 2 SCAF15106, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15106, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 242
Score = 83.8 bits (198), Expect = 5e-15
Identities = 39/98 (39%), Positives = 55/98 (56%)
Frame = +1
Query: 382 RTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGE 561
R GT+ D+ L K + LGF V + ++ E + +++ SE DH+D+ C +LSHGE
Sbjct: 4 RNGTDRDAGELYKCFKSLGFDVFIYNDQTCEKMEHLLREASEEDHSDSSCFACILLSHGE 63
Query: 562 LGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQ 675
GM+Y D + F D C +L GKPKLFFIQ
Sbjct: 64 EGMIYGTDGAMPIKTMTSMFRGDMCKSLVGKPKLFFIQ 101
>UniRef50_Q0PKX0 Cluster: Caspase Xa; n=4; Danio rerio|Rep: Caspase
Xa - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 345
Score = 83.8 bits (198), Expect = 5e-15
Identities = 48/129 (37%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y + N RG+ +I N+ F ++K R G++ D L+KV R LGF V N A ++
Sbjct: 106 YKITQNPRGICVIINNVDFT--SMKERRGSDEDQKYLAKVFRWLGFEVVAHRNKTAAEMK 163
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+Q + D DC + VLSHG + G+ D + FT C L GKPK
Sbjct: 164 NILQALGRT--VDGDCFVCCVLSHGMKEGVCGTDGDLVSVDEIRDPFTGINCQKLVGKPK 221
Query: 661 LFFIQACQG 687
LFFIQAC+G
Sbjct: 222 LFFIQACRG 230
>UniRef50_Q0Z8U7 Cluster: Caspase-8; n=1; Haemaphysalis
longicornis|Rep: Caspase-8 - Haemaphysalis longicornis
(Bush tick)
Length = 306
Score = 83.0 bits (196), Expect = 1e-14
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 3/133 (2%)
Frame = +1
Query: 298 HYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAED 477
H Y M RG+ II N+ F + R G+ VD + + L F V +L A+D
Sbjct: 47 HVYPMTQKPRGLCIIINNVDFG-NRFPKRHGSEVDVRRMEDLFEALFFRVQTHRDLSADD 105
Query: 478 INRYIQQISEMDHTDN-DCLLVAVLSHGELGMLYAKDTHYK--PDNLWYYFTADKCPTLA 648
+ + ++ D N +CL+V ++SHGE +Y D + ++ F CP+L
Sbjct: 106 MKSVLSDAAKEDKQKNAECLVVILMSHGENDGIYGTDGKWLNLKQEVYTQFNDSNCPSLQ 165
Query: 649 GKPKLFFIQACQG 687
GKPKLFF+QAC+G
Sbjct: 166 GKPKLFFVQACRG 178
>UniRef50_Q7ZXD2 Cluster: MGC53258 protein; n=3; Xenopus|Rep:
MGC53258 protein - Xenopus laevis (African clawed frog)
Length = 419
Score = 81.8 bits (193), Expect = 2e-14
Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 4/132 (3%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y M+ RG A++ ++ FE +L R G VD SL K+ LG+ V V NL A+ +
Sbjct: 161 YKMHSCPRGRALLISNVKFETPDLDYRCGGEVDLASLEKLFSSLGYQVDVRCNLNAQSMM 220
Query: 484 RYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTA---DKCPTLAG 651
++ S + H+ D +VA+LSHG G +Y D K L FTA CP L
Sbjct: 221 SQLRAFSALPVHSSLDSCVVAILSHGLDGAVYGTDG--KLVQLQEVFTALDNAHCPQLQN 278
Query: 652 KPKLFFIQACQG 687
KPK+FF QAC+G
Sbjct: 279 KPKMFFFQACRG 290
>UniRef50_P42575 Cluster: Caspase-2 precursor (EC 3.4.22.55)
(CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural
precursor cell expressed developmentally down- regulated
protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18;
Caspase-2 subunit p13; Caspase-2 subunit p12]; n=34;
Euteleostomi|Rep: Caspase-2 precursor (EC 3.4.22.55)
(CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural
precursor cell expressed developmentally down- regulated
protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18;
Caspase-2 subunit p13; Caspase-2 subunit p12] - Homo
sapiens (Human)
Length = 452
Score = 81.8 bits (193), Expect = 2e-14
Identities = 44/131 (33%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y + RG+A++ ++ HF L+ R+G +VD +L + + LG+ V VL + A+++
Sbjct: 192 YRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEM 251
Query: 481 NRYIQQISEMD-HTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGK 654
+Q +++ H D +VA+LSHG G +Y D + ++ F CP+L K
Sbjct: 252 QEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNK 311
Query: 655 PKLFFIQACQG 687
PK+FFIQAC+G
Sbjct: 312 PKMFFIQACRG 322
>UniRef50_Q8JIS8 Cluster: Caspase 3A; n=3; Euteleostomi|Rep: Caspase
3A - Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 290
Score = 80.6 bits (190), Expect = 5e-14
Identities = 40/129 (31%), Positives = 70/129 (54%), Gaps = 1/129 (0%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y+M++ G+ +I N+++F + + R GT+ D+ + K LG+ + + ++ + +
Sbjct: 50 YSMDYPKMGICLIINNKNFHKDSGMGPRNGTDNDAAAAWKSFMKLGYEIQMYNDQTVDQM 109
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 660
+ +Q+S DH+ +LSHGE G++Y D + L C +L GKPK
Sbjct: 110 KKLFRQMSNQDHSKFASFACVILSHGEEGVIYGTDGPVSFNKLIECLKGRSCLSLVGKPK 169
Query: 661 LFFIQACQG 687
LFFIQAC+G
Sbjct: 170 LFFIQACRG 178
>UniRef50_A7S4V9 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 358
Score = 79.0 bits (186), Expect = 2e-13
Identities = 41/130 (31%), Positives = 71/130 (54%), Gaps = 2/130 (1%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHN-LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y MN + G +I N+ F+ + LKSR G+++D+ +L + L + V L++L +
Sbjct: 119 YKMNRDPHGWCLIINNVRFDADSGLKSRAGSDIDASNLQSLFMSLRYRVKRLNDLTMRQM 178
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKP 657
+ ++ +H ++D ++V +LSHG G +Y D ++ F + L GKP
Sbjct: 179 KNTLFDFAKNNHKNSDSVVVCILSHGLEGRIYGVDGGLLNISDVISMFNGYQAKDLIGKP 238
Query: 658 KLFFIQACQG 687
KLFF+QAC+G
Sbjct: 239 KLFFLQACRG 248
>UniRef50_Q6KF63 Cluster: Caspase 10; n=3; Catarrhini|Rep: Caspase
10 - Homo sapiens (Human)
Length = 455
Score = 79.0 bits (186), Expect = 2e-13
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Frame = +1
Query: 403 SDSLSKVLRGLGFSVTVLHNLRAEDINRYIQ-QISEMDHTDNDCLLVAVLSHGELGMLYA 579
++ LS V + LGF+V + +N+ ++ +Q Q H D DC + +L+HG G +Y+
Sbjct: 240 NEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYS 299
Query: 580 KDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
D P + +FTA +CP LA KPKLFFIQACQG
Sbjct: 300 SDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQG 336
>UniRef50_UPI0000F1EBE3 Cluster: PREDICTED: similar to caspase 10;
n=2; Danio rerio|Rep: PREDICTED: similar to caspase 10 -
Danio rerio
Length = 306
Score = 78.2 bits (184), Expect = 3e-13
Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 14/142 (9%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVD-------------SDSLSKVLRGLGFS 444
Y M RG+ +I N+ F +R GT++D SDSL V LGF
Sbjct: 46 YEMKGERRGVCLIINNYDFSACGWLNREGTDIDHAPVSKCVLFYVYSDSLRDVFEWLGFE 105
Query: 445 VTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYF 621
+ + + I + + +S DHT DC++ +LSHG L + D P L
Sbjct: 106 ILTRRDCTGDQILQALMDLSTQDHTQADCVVCCILSHGRLNDIIGVDGKAVPFKELMETL 165
Query: 622 TADKCPTLAGKPKLFFIQACQG 687
+ +C +L KPKLFFIQAC+G
Sbjct: 166 SPFRCSSLYQKPKLFFIQACRG 187
>UniRef50_UPI0000E45DDA Cluster: PREDICTED: similar to caspase 3;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to caspase 3 - Strongylocentrotus purpuratus
Length = 526
Score = 78.2 bits (184), Expect = 3e-13
Identities = 40/126 (31%), Positives = 71/126 (56%), Gaps = 5/126 (3%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ-I 501
+G+ +I N+ HF H K R G+ VD +++ V R +G+ ++ NL A +I ++ + +
Sbjct: 222 KGLILILNNNHF--HEGKDRPGSEVDLENIEHVFRQIGYEPVIMKNLSANEIRSFLDKSV 279
Query: 502 SEMD---HTDNDCLLVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFF 669
S ++ + +++ ++SHGE +Y D + F+ +CP L GKPK+FF
Sbjct: 280 SRINLEGSIRHSSVVLVLMSHGEKRGIYGTDLEVVTIQEIKSKFSGRQCPALLGKPKIFF 339
Query: 670 IQACQG 687
IQAC+G
Sbjct: 340 IQACRG 345
>UniRef50_Q4SNC6 Cluster: Chromosome 8 SCAF14543, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
SCAF14543, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 397
Score = 78.2 bits (184), Expect = 3e-13
Identities = 48/133 (36%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFE---IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 474
Y M + RG+A++ ++ F +L R G VD + L KV L + VTV +L A+
Sbjct: 160 YKMTSSPRGLALVISNVRFSPFAAPDLDPRQGGEVDDEVLRKVFTELDYLVTVQRDLTAQ 219
Query: 475 DINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLA 648
I I+ S +H D +V +LSHG G +Y D + D ++ F CP L
Sbjct: 220 GIKTCIENFSRRPEHQSVDSCVVCLLSHGVEGAVYGVDGKLLQLDWVFTAFDNAHCPLLQ 279
Query: 649 GKPKLFFIQACQG 687
KPK+FFIQAC+G
Sbjct: 280 NKPKMFFIQACRG 292
>UniRef50_Q4FJK5 Cluster: Casp9 protein; n=20; Eutheria|Rep: Casp9
protein - Mus musculus (Mouse)
Length = 454
Score = 77.8 bits (183), Expect = 4e-13
Identities = 48/137 (35%), Positives = 72/137 (52%), Gaps = 9/137 (6%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y ++ + G +I N+ +F L +RTG+N+D D L R L F V V ++L A+ +
Sbjct: 191 YTLDSDPCGHCLIINNVNFCPSSGLGTRTGSNLDRDKLEHRFRWLRFMVEVKNDLTAKKM 250
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKC 636
+ +++ +H DC +V +LSHG L G +Y D + + F C
Sbjct: 251 VTALMEMAHRNHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIEKIVNIFNGSGC 310
Query: 637 PTLAGKPKLFFIQACQG 687
P+L GKPKLFFIQAC G
Sbjct: 311 PSLGGKPKLFFIQACGG 327
>UniRef50_Q5D0W5 Cluster: Caspase 3C; n=2; Hydra vulgaris|Rep:
Caspase 3C - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 326
Score = 77.4 bits (182), Expect = 5e-13
Identities = 45/133 (33%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = +1
Query: 298 HYYNMNHNNRGMAIIFNHEHFEIHNLKS---RTGTNVDSDSLSKVLRGLGFSVTVLHNLR 468
++Y+ N RG I N +F + + R GT+VD+ SL + LGF + L N +
Sbjct: 74 NFYDTNTFPRGTLTIINVNNFMKSSGRHDDPRLGTDVDAQSLCDLFLKLGFKIDRLDNPK 133
Query: 469 AEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLA 648
+ D+ ++Q + D++ C +VA+LSHGE G ++ + + F + LA
Sbjct: 134 STDVLNILKQAANEDYSSMSCCVVALLSHGEEGKIFCTNESLNIREITNLFCTN---ALA 190
Query: 649 GKPKLFFIQACQG 687
GKPKLF IQAC+G
Sbjct: 191 GKPKLFLIQACRG 203
>UniRef50_A7S119 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 229
Score = 77.4 bits (182), Expect = 5e-13
Identities = 38/122 (31%), Positives = 64/122 (52%), Gaps = 1/122 (0%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
+G +I N++ F + R G+ D L ++ G +V + N + ++ +++ S
Sbjct: 2 KGYVLIINNQEFPSRSDVERKGSAEDVKQLYQLFDDFGMTVKTIQNKTSLEMLELLEETS 61
Query: 505 EMDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKLFFIQAC 681
E D T DC + +LSHG +Y D + ++L F CP+L GKPK+FF+QAC
Sbjct: 62 EKDFTKFDCFICIILSHGSHSGIYGVDEKAVQVESLTNKFRGSTCPSLQGKPKVFFLQAC 121
Query: 682 QG 687
+G
Sbjct: 122 RG 123
>UniRef50_A7S9L1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 262
Score = 76.6 bits (180), Expect = 8e-13
Identities = 42/136 (30%), Positives = 75/136 (55%), Gaps = 8/136 (5%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEI------HNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH-N 462
Y M + +G A+IFN++ F+ R G++ D+ SL ++ + F V + +
Sbjct: 3 YKMTSSPKGYAVIFNYKKFDSSLKFPSEKFDERLGSDKDTASLVRLWKAYDFEVPEPYLD 62
Query: 463 LRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDT-HYKPDNLWYYFTADKCP 639
L ++ + +++ D++ DCL + ++SHG+ +Y D K + + F+ +C
Sbjct: 63 LSYDETKAAVNKLALKDYSQYDCLAIFLMSHGKEDFIYTSDGGELKINEIRKRFSNARCR 122
Query: 640 TLAGKPKLFFIQACQG 687
+LAGKPKLFFIQAC+G
Sbjct: 123 SLAGKPKLFFIQACRG 138
>UniRef50_P42573 Cluster: Cell death protein 3 precursor (EC
3.4.22.-) [Contains: Cell death protein 3 subunit 1;
Cell death protein 3 subunit 2]; n=3;
Caenorhabditis|Rep: Cell death protein 3 precursor (EC
3.4.22.-) [Contains: Cell death protein 3 subunit 1;
Cell death protein 3 subunit 2] - Caenorhabditis elegans
Length = 503
Score = 76.6 bits (180), Expect = 8e-13
Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
RGM +I N+EHFE + +R GT D D+L+ + R +G++V NL + I+ +
Sbjct: 242 RGMCLIINNEHFE--QMPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFA 299
Query: 505 EMDHTDNDCLLVAVLSHGELGMLYA-KDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQAC 681
+ + + +LV +LSHGE ++ D ++ A P LA KPK+ F+QAC
Sbjct: 300 KHESHGDSAILV-ILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQAC 358
Query: 682 QG 687
+G
Sbjct: 359 RG 360
>UniRef50_P55211 Cluster: Caspase-9 precursor (EC 3.4.22.62)
(CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
(Apoptotic protease Mch-6) (Apoptotic protease-
activating factor 3) (APAF-3) [Contains: Caspase-9
subunit p35; Caspase-9 subunit p10]; n=23;
Tetrapoda|Rep: Caspase-9 precursor (EC 3.4.22.62)
(CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
(Apoptotic protease Mch-6) (Apoptotic protease-
activating factor 3) (APAF-3) [Contains: Caspase-9
subunit p35; Caspase-9 subunit p10] - Homo sapiens
(Human)
Length = 416
Score = 76.6 bits (180), Expect = 8e-13
Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 9/129 (6%)
Frame = +1
Query: 328 GMAIIFNHEHF-EIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
G +I N+ +F L++RTG+N+D + L + L F V V +L A+ + + +++
Sbjct: 161 GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELA 220
Query: 505 EMDHTDNDCLLVAVLSHG----EL---GMLYAKD-THYKPDNLWYYFTADKCPTLAGKPK 660
+ DH DC +V +LSHG L G +Y D + + F CP+L GKPK
Sbjct: 221 QQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPK 280
Query: 661 LFFIQACQG 687
LFFIQAC G
Sbjct: 281 LFFIQACGG 289
>UniRef50_Q9IB64 Cluster: Caspase-8; n=1; Xenopus laevis|Rep:
Caspase-8 - Xenopus laevis (African clawed frog)
Length = 500
Score = 75.4 bits (177), Expect = 2e-12
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKS-----RTGTNVDSDSLSKVLRGLGFSVTVLHNLR 468
Y++ N G ++ N+ F+ + R GT D++ ++++ G+ +L
Sbjct: 253 YHLEKNPHGWCVVINNYDFKEARSQDCKYTDREGTAKDAEEITRIFNARGYITEEHRDLT 312
Query: 469 AEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD-THYKPDNLWYYFTADKCPTL 645
A +I + ++ S+ DH + D + +LSHG +G + D + L YF C +L
Sbjct: 313 AANIQKTLEMYSKKDHAEKDSFVCFILSHGGVGTVCGCDGEEVEIKRLTKYFNGQHCRSL 372
Query: 646 AGKPKLFFIQACQG 687
KPK+FFIQACQG
Sbjct: 373 INKPKIFFIQACQG 386
>UniRef50_Q8I749 Cluster: Caspase-related protein; n=1; Suberites
domuncula|Rep: Caspase-related protein - Suberites
domuncula (Sponge)
Length = 496
Score = 74.5 bits (175), Expect = 3e-12
Identities = 39/134 (29%), Positives = 75/134 (55%), Gaps = 5/134 (3%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHNLK----SRTGTNVDSDSLSKVLRGLGFSVTVLHNLR 468
+Y MN N G+ +I N+ F + + +R G ++D +L++ + L + V V+ N+
Sbjct: 245 FYPMNKNPHGICLIINNHQFYHSDPEKCHSNRGGAHIDVHNLTQTFKYLRYKVEVVENIS 304
Query: 469 AEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADK-CPTL 645
+ ++N+ + + + DH D + +++ G +++ D+ + NL+ K CPTL
Sbjct: 305 SSEMNKVMLRKASEDHPQYDSFVCIIMTQGGSNIVHGADS--EAVNLYDLTGVMKMCPTL 362
Query: 646 AGKPKLFFIQACQG 687
GKPK+FF+QAC+G
Sbjct: 363 RGKPKIFFVQACRG 376
>UniRef50_Q07BT4 Cluster: Caspase-1; n=2; Percomorpha|Rep: Caspase-1
- Dicentrarchus labrax (European sea bass)
Length = 394
Score = 72.9 bits (171), Expect = 1e-11
Identities = 37/110 (33%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
Frame = +1
Query: 379 SRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHT-DNDCLLVAVLSH 555
+R G D +++ K+L+ LG+ V NL A++I+ + + S+ + D +LV ++SH
Sbjct: 159 NRKGAEKDQENMEKLLKALGYDVVKRTNLTAKEIDAAMIEFSKNPKLRETDSVLVVIMSH 218
Query: 556 GELGML----YAKDT--HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
G+LG + YA+D + +N++ + ++KCP L KPK+ IQAC+G
Sbjct: 219 GKLGAVLGVNYAEDNPDEFPINNIYEHLGSEKCPALLNKPKIIIIQACRG 268
>UniRef50_Q16PQ5 Cluster: Ecdysone-inducible caspase, putative; n=2;
Culicidae|Rep: Ecdysone-inducible caspase, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 449
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 9/184 (4%)
Frame = +1
Query: 163 DEEKKNNGSGTEQRKNGNEDEGDAWGSHGSS--QGRRYAKMPVERYAHYYNMNHNNRGMA 336
D+ K NN + E G + +G S + A+ R Y M NRG+
Sbjct: 148 DDAKNNNDTVEETTDKGGKRRLQEFGEKVRSLYKVELSARPQSHRILEAYEMRRRNRGVV 207
Query: 337 IIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDH 516
I N + +R G D +L + + LGF+V +L +++ N I+++ + +
Sbjct: 208 FIVNVITYINETHPTRNGAEADKYNLVSLFQQLGFTVFYYEDLTSDEFNNLIKELKQSSY 267
Query: 517 TDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYY-------FTADKCPTLAGKPKLFFIQ 675
+C + +L+HG +D Y DN Y F CP L +PKLFF
Sbjct: 268 LSTECFVFYILAHG--NHTKGRDKIYLNDNSVLYVEDVLALFNNANCPKLIRRPKLFFFS 325
Query: 676 ACQG 687
C+G
Sbjct: 326 ICRG 329
>UniRef50_UPI0000E48C15 Cluster: PREDICTED: similar to caspase 8;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to caspase 8 - Strongylocentrotus purpuratus
Length = 300
Score = 71.3 bits (167), Expect = 3e-11
Identities = 39/86 (45%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Frame = +1
Query: 433 LGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD-THYKPDNL 609
L F V + A D +QQI+ MDHT DC + +LSHG G +Y D D L
Sbjct: 104 LKFKTYVKKDPTARDYVASLQQIANMDHTKFDCFVCVILSHGCRGSVYGTDGKKVSIDAL 163
Query: 610 WYYFTADKCPTLAGKPKLFFIQACQG 687
F D P+L KPKLFFIQACQG
Sbjct: 164 TGLFRGDYVPSLVNKPKLFFIQACQG 189
>UniRef50_UPI0000E82482 Cluster: PREDICTED: hypothetical protein;
n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 266
Score = 70.9 bits (166), Expect = 4e-11
Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLS 552
L+ R G +++ LS+VL L + V +LHN A+++ QQ +H D + + S
Sbjct: 26 LRPRRGARREAEKLSRVLAQLSYRVKLLHNRTAKEMEDLYQQECSREH--GDYFVSVISS 83
Query: 553 HGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
HGE G + D + +++ +A CP LA +PK+FFIQAC+G
Sbjct: 84 HGEEGAVLGCDCRPLRLTRIFHIVSAQNCPALAERPKVFFIQACRG 129
>UniRef50_Q9Y1U6 Cluster: Cell death protein CED-3; n=1;
Pristionchus pacificus|Rep: Cell death protein CED-3 -
Pristionchus pacificus
Length = 417
Score = 70.1 bits (164), Expect = 7e-11
Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 3/124 (2%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKV-LRGLGFSVTVLHNLRAEDINRYIQQI 501
RG A+I ++EHF + R GT D +L + + LG+ V V NL ++++ I+
Sbjct: 172 RGYALIISNEHFR--TMPQRRGTKADVIALKNLFISKLGYEVEVHENLTGKELHNNIKSF 229
Query: 502 -SEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDN-LWYYFTADKCPTLAGKPKLFFIQ 675
S H+ +V +L+HGE +LY D + L F P LAGKPK+ +Q
Sbjct: 230 ASSTKHSFTSSAIVCILTHGEHDVLYGVDDQVVDVHYLLSSFNTHNAPHLAGKPKIILLQ 289
Query: 676 ACQG 687
AC+G
Sbjct: 290 ACRG 293
>UniRef50_Q9TZP6 Cluster: Caspase-related protein 1B; n=3;
Caenorhabditis elegans|Rep: Caspase-related protein 1B -
Caenorhabditis elegans
Length = 268
Score = 70.1 bits (164), Expect = 7e-11
Identities = 47/144 (32%), Positives = 78/144 (54%), Gaps = 2/144 (1%)
Frame = +1
Query: 262 RRYAKMPVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 441
R AK ++ + Y MN N RG +I ++E+F+ N++ R GT D +L+K+ + L +
Sbjct: 3 RTDAKKSNHKHKYCYEMNSNPRGTVLILSNENFK--NMERRVGTKQDEVNLTKLFQKLQY 60
Query: 442 SVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLSHGE-LGMLYAKDTHYKPDNLWYY 618
+V NL AE + I++ +EM HTD+ +++ +LSHG+ G ++ D P N+
Sbjct: 61 TVICKRNLEAESMLEAIKEFAEMAHTDS--IILFLLSHGDGAGSVFGIDD--MPVNVMEV 116
Query: 619 FT-ADKCPTLAGKPKLFFIQACQG 687
T L KPK + AC+G
Sbjct: 117 STYLAYHQNLLLKPKWVAVSACRG 140
>UniRef50_UPI0000661247 Cluster: Homolog of Brachydanio rerio
"Caspase.; n=4; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Caspase. - Takifugu rubripes
Length = 358
Score = 69.3 bits (162), Expect = 1e-10
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Frame = +1
Query: 319 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 498
NNR +I N F H +R G D +++ +L+GLG+ V NL I +
Sbjct: 112 NNRVALVITNITFF--HQCLNRKGAEKDEENMETLLKGLGYEVVKYRNLTGRAIEDAVID 169
Query: 499 ISEMDHT-DNDCLLVAVLSHGELGMLYAKDTH--------YKPDNLWYYFTADKCPTLAG 651
S+ D D ++V ++SHG LG++ T + D ++ + + CP L
Sbjct: 170 FSKRPKLKDTDSVVVVIMSHGRLGVVAGVSTQSPTFEDDLFSLDKIYRHLGPEHCPALLN 229
Query: 652 KPKLFFIQACQG 687
KPK+ IQAC+G
Sbjct: 230 KPKIIIIQACRG 241
>UniRef50_UPI0000587370 Cluster: PREDICTED: similar to caspase 8,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to caspase 8, partial -
Strongylocentrotus purpuratus
Length = 447
Score = 68.9 bits (161), Expect = 2e-10
Identities = 33/95 (34%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLR-GLGFSVTVLHNLRAEDI 480
Y M++ RG+ IIFN E+F + +LK R GT D ++L + L F+ V ++ +
Sbjct: 343 YKMDNTPRGICIIFNAENFAVEHLKKRKGTQKDVEALENTFQNNLKFTTQVKNDPTKNEY 402
Query: 481 NRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKD 585
+Q+I MDH+ DC + +LSHG G ++ D
Sbjct: 403 KECLQEIRRMDHSKYDCFVCVILSHGCEGHVFGTD 437
>UniRef50_UPI000065FEF6 Cluster: Homolog of Ictalurus punctatus
"Caspase 8.; n=1; Takifugu rubripes|Rep: Homolog of
Ictalurus punctatus "Caspase 8. - Takifugu rubripes
Length = 340
Score = 68.9 bits (161), Expect = 2e-10
Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Frame = +1
Query: 328 GMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISE 507
G+ +I N+E+F ++K R+GTN D+ SL++V LGF V + + E ++R + +
Sbjct: 116 GLCVIINNENFL--DMKQRSGTNKDAQSLAEVFTWLGFRVLMCKDQTKEKMDRAFVDL-Q 172
Query: 508 MDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKLFFIQACQ 684
+D D + +LSHGE + D + F A + L KPK+F IQACQ
Sbjct: 173 VDPKHGDAFICCILSHGEKSAVLGIDGEPLCIKQIIRTFKATRQSALVSKPKMFLIQACQ 232
Query: 685 G 687
G
Sbjct: 233 G 233
>UniRef50_Q9GV89 Cluster: Caspase 3A; n=1; Hydra vulgaris|Rep:
Caspase 3A - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 347
Score = 68.5 bits (160), Expect = 2e-10
Identities = 44/132 (33%), Positives = 70/132 (53%), Gaps = 3/132 (2%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRG-LGFSVTVLHNLRAED 477
YY ++ G +I N+E F ++R G+ VD +L+ +G LG+ V +NL+ ED
Sbjct: 87 YYTLS---TGFVLIINNEKFVEE--ENRDGSEVDVQALNSFFKGTLGWCVKSCNNLKRED 141
Query: 478 INRYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTH-YKPDNLWYYFTADKCPTLAG 651
I + +S++ L + +LSHG E G+L + K ++L F AD P
Sbjct: 142 IINIVYSLSQVKCFPFSALFIVILSHGSESGILGIDSSEEIKINSLLENFKADNAPAFDK 201
Query: 652 KPKLFFIQACQG 687
KPK+F +QAC+G
Sbjct: 202 KPKVFIVQACRG 213
>UniRef50_P29466-4 Cluster: Isoform Delta of P29466 ; n=2;
Euarchontoglires|Rep: Isoform Delta of P29466 - Homo
sapiens (Human)
Length = 263
Score = 68.1 bits (159), Expect = 3e-10
Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 7/131 (5%)
Frame = +1
Query: 331 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 510
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 71 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 128
Query: 511 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 669
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 129 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 188
Query: 670 IQACQG**VRW 702
IQAC+G V W
Sbjct: 189 IQACRGDNVSW 199
>UniRef50_Q504J1 Cluster: Caspase b; n=7; Danio rerio|Rep: Caspase b
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 404
Score = 68.1 bits (159), Expect = 3e-10
Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 6/127 (4%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
+G+A++ + F + +R G + D ++ +LR LGF+V NL +DI R ++ S
Sbjct: 173 KGLALLITNIQFA-NTQHNRNGADRDEENAEWLLRSLGFAVIKYRNLSGKDIRRAVENFS 231
Query: 505 EM-DHTDNDCLLVAVLSHGEL-----GMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLF 666
+ +H D D + ++SHG ++ D Y + + + + CP L KPK+
Sbjct: 232 KRREHEDADSTFIVIMSHGTRIDNKDAIVGVSDDVYFIEETFSHLNSVNCPALIDKPKVI 291
Query: 667 FIQACQG 687
IQAC+G
Sbjct: 292 LIQACRG 298
>UniRef50_UPI0000E47F37 Cluster: PREDICTED: similar to caspase-3,
partial; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to caspase-3, partial -
Strongylocentrotus purpuratus
Length = 608
Score = 67.7 bits (158), Expect = 4e-10
Identities = 33/127 (25%), Positives = 65/127 (51%), Gaps = 1/127 (0%)
Frame = +1
Query: 310 MNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRY 489
M+ N+G+ + N+ F + R G++VD ++ V +G++ NL AE I +
Sbjct: 1 MDERNKGLVFVLNNYLFGPDRTRERKGSDVDLANVKHVFTEIGYTADEAQNLTAEGIRQK 60
Query: 490 IQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLF 666
++ +++ + + +++ +SHG E G+ + + F+ + CP L GKPK+
Sbjct: 61 LKSLTQKILSSHTSVVLVFMSHGKEAGIQGTDEEVVTVKEIKDMFSGNNCPALIGKPKIM 120
Query: 667 FIQACQG 687
QAC+G
Sbjct: 121 IFQACRG 127
>UniRef50_Q9I9L7 Cluster: Caspase; n=2; Danio rerio|Rep: Caspase -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 383
Score = 67.3 bits (157), Expect = 5e-10
Identities = 36/128 (28%), Positives = 73/128 (57%), Gaps = 9/128 (7%)
Frame = +1
Query: 331 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 510
+A++ N+ F+ +K R+G+ D +++ K+L+ L + V NL A++++ I+ ++
Sbjct: 146 LALLINNVDFDDKAMK-RSGSEKDEENMEKLLKELDYQVVKRPNLSAKEMDEAIRDFAQR 204
Query: 511 D-HTDNDCLLVAVLSHGE----LGMLYAKDTH----YKPDNLWYYFTADKCPTLAGKPKL 663
+ H +D V ++SHG+ +G+ Y + + + DN++ ++ CP L KPK+
Sbjct: 205 EEHKYSDSAFVVIMSHGKRDAIMGVHYHRTNNPSDSFPVDNVYRRLNSENCPALRDKPKV 264
Query: 664 FFIQACQG 687
IQAC+G
Sbjct: 265 ILIQACRG 272
>UniRef50_Q5SVL3 Cluster: Caspase 7, apoptosis-related cysteine
peptidase; n=4; Homo sapiens|Rep: Caspase 7,
apoptosis-related cysteine peptidase - Homo sapiens
(Human)
Length = 253
Score = 66.9 bits (156), Expect = 7e-10
Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 298 HYYNMNHNNRGMAIIFNHEHFE-IHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 474
+ YNMN G II N+++F+ + + R GT+ D+++L K R LGF V V ++
Sbjct: 58 YQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCA 117
Query: 475 DINRYIQQISEMDHTDNDCLLVAVLSHGELGM 570
+ +++ SE DHT+ C +LSHGE M
Sbjct: 118 KMQDLLKKASEEDHTNAACFACILLSHGEENM 149
>UniRef50_UPI0000E4A098 Cluster: PREDICTED: similar to CGI-141
protein; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to CGI-141 protein -
Strongylocentrotus purpuratus
Length = 225
Score = 66.5 bits (155), Expect = 9e-10
Identities = 29/72 (40%), Positives = 48/72 (66%), Gaps = 1/72 (1%)
Frame = +1
Query: 475 DINRYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAG 651
DI + I+Q+ + +H+ C + +L+HG+ G +Y D + +++ F++D CPTL G
Sbjct: 25 DIRQVIEQLGKHNHSQFYCFIFTILTHGKEGSVYGTDECLVRIEDIVGRFSSDLCPTLNG 84
Query: 652 KPKLFFIQACQG 687
KPKLFF+QAC+G
Sbjct: 85 KPKLFFLQACRG 96
>UniRef50_Q5C0Y4 Cluster: SJCHGC07329 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07329 protein - Schistosoma
japonicum (Blood fluke)
Length = 239
Score = 66.1 bits (154), Expect = 1e-09
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 337 IIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-D 513
II E+ + SR G++ D L + +SV V+ N+ E++ + +++ + +
Sbjct: 1 IINIEEYSRESGVSSRLGSSHDVTKLQLLFEDFMYSVAVIRNVNGENLIKVVREFARKPE 60
Query: 514 HTDNDCLLVAVLSHGELGMLYAKD-THYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
H + ++ +L+HG + A D H D L FT +CP LAGKPK IQAC+G
Sbjct: 61 HNNVHAAVLIILAHGLEHHIIASDGIHVSIDELVSCFTNKRCPLLAGKPKFILIQACRG 119
>UniRef50_P29466-2 Cluster: Isoform Beta of P29466 ; n=11;
Theria|Rep: Isoform Beta of P29466 - Homo sapiens
(Human)
Length = 383
Score = 65.7 bits (153), Expect = 2e-09
Identities = 40/126 (31%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Frame = +1
Query: 331 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 510
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 143 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 200
Query: 511 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 669
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 201 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 260
Query: 670 IQACQG 687
IQAC+G
Sbjct: 261 IQACRG 266
>UniRef50_P29466 Cluster: Caspase-1 precursor (EC 3.4.22.36)
(CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1
beta-converting enzyme) (ICE) (Interleukin- 1
beta-converting enzyme) (p45) [Contains: Caspase-1
subunit p20; Caspase-1 subunit p10]; n=29; Eutheria|Rep:
Caspase-1 precursor (EC 3.4.22.36) (CASP-1)
(Interleukin-1 beta convertase) (IL-1BC) (IL-1
beta-converting enzyme) (ICE) (Interleukin- 1
beta-converting enzyme) (p45) [Contains: Caspase-1
subunit p20; Caspase-1 subunit p10] - Homo sapiens
(Human)
Length = 404
Score = 65.7 bits (153), Expect = 2e-09
Identities = 40/126 (31%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Frame = +1
Query: 331 MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM 510
+A+I +E F+ ++ RTG VD ++ +L+ LG+SV V NL A D+ ++ +
Sbjct: 164 LALIICNEEFD--SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
Query: 511 -DHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFF 669
+H +D + +SHG G+ K + PD L + CP+L KPK+
Sbjct: 222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVII 281
Query: 670 IQACQG 687
IQAC+G
Sbjct: 282 IQACRG 287
>UniRef50_UPI0000F2CF2E Cluster: PREDICTED: similar to caspase 12;
n=1; Monodelphis domestica|Rep: PREDICTED: similar to
caspase 12 - Monodelphis domestica
Length = 405
Score = 64.9 bits (151), Expect = 3e-09
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 7/112 (6%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVL 549
L R G +D + K+L LG++V + NL A+ + +++ ++ +H +D + +
Sbjct: 176 LDERQGAYLDIWGMWKLLENLGYTVIIKTNLTAQKMESVLKEFADRPEHLSSDSTFLVFM 235
Query: 550 SHGEL-GMLYAKDTHYKPDNL-----WYYFTADKCPTLAGKPKLFFIQACQG 687
SHG L G+ + T KPD L + F CP+L GKPK+ IQAC+G
Sbjct: 236 SHGLLNGICGIEHTKQKPDLLATDVIFQIFNDSNCPSLKGKPKVIIIQACRG 287
>UniRef50_UPI00006A1E20 Cluster: Caspase-9 precursor (EC 3.4.22.62)
(CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
(Apoptotic protease Mch-6) (Apoptotic protease-
activating factor 3) (APAF-3) [Contains: Caspase-9
subunit p35; Caspase-9 subunit p10].; n=1; Xenopus
tropicalis|Rep: Caspase-9 precursor (EC 3.4.22.62)
(CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
(Apoptotic protease Mch-6) (Apoptotic protease-
activating factor 3) (APAF-3) [Contains: Caspase-9
subunit p35; Caspase-9 subunit p10]. - Xenopus
tropicalis
Length = 141
Score = 64.5 bits (150), Expect = 4e-09
Identities = 39/98 (39%), Positives = 55/98 (56%), Gaps = 8/98 (8%)
Frame = +1
Query: 490 IQQISEMDHTDNDCLLVAVLSHG-EL------GMLYAKDTHYKP-DNLWYYFTADKCPTL 645
+++++ DH+ DC LV +LSHG E G +Y D P + + YF KCP+L
Sbjct: 1 LEELAAQDHSLRDCCLVVILSHGCETRHIQFPGGVYGTDGIRIPVERIVSYFNGSKCPSL 60
Query: 646 AGKPKLFFIQACQG**VRWWNNIIQH*NRWFFVFILQN 759
GKPK+FFIQAC G V W + +H W +V +L N
Sbjct: 61 RGKPKIFFIQACGGGYVSWRD---KHTGSW-YVEVLDN 94
>UniRef50_Q28GK9 Cluster: Novel protein; n=1; Xenopus
tropicalis|Rep: Novel protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 239
Score = 64.5 bits (150), Expect = 4e-09
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Frame = +1
Query: 343 FNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTD 522
F+ H E+ +L R G D + L KVL LG+ V++ ++ A++I Q+ S+M
Sbjct: 13 FHPRHGEVGSLDQRKGVKRDVNRLFKVLSRLGYKVSLHMDVSAKEIKDIYQKESKM--PQ 70
Query: 523 NDCLLVAVLSHGELGMLY-AKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+ + + SHG G++Y T +L+ + P LAG PKLFF+QAC+G
Sbjct: 71 GESFISILSSHGNEGLIYDFYGTPVLLRDLYDILAPNNSPLLAGVPKLFFVQACRG 126
>UniRef50_P49662 Cluster: Caspase-4 precursor (EC 3.4.22.57)
(CASP-4) (ICH-2 protease) (TX protease) (ICE(rel)-II)
[Contains: Caspase-4 subunit 1; Caspase-4 subunit 2];
n=10; Mammalia|Rep: Caspase-4 precursor (EC 3.4.22.57)
(CASP-4) (ICH-2 protease) (TX protease) (ICE(rel)-II)
[Contains: Caspase-4 subunit 1; Caspase-4 subunit 2] -
Homo sapiens (Human)
Length = 377
Score = 63.3 bits (147), Expect = 8e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Frame = +1
Query: 211 GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNH-NNRG-MAIIFNHEHFEIHNLKSR 384
G + G++ + + ++ ER Y + NNR +A+I + F+ +L R
Sbjct: 95 GPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPR 152
Query: 385 TGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGE 561
G + D + ++L GL +SV V NL A D+ ++ + +H +D + ++SHG
Sbjct: 153 NGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGI 212
Query: 562 L-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 687
L G+ KPD L Y F C +L KPK+ +QAC+G
Sbjct: 213 LEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG 260
>UniRef50_Q9Y055 Cluster: Caspase-related protein 2A; n=3;
Caenorhabditis elegans|Rep: Caspase-related protein 2A -
Caenorhabditis elegans
Length = 826
Score = 62.9 bits (146), Expect = 1e-08
Identities = 38/128 (29%), Positives = 65/128 (50%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y N +++ AII N+ F ++ R G++ D LSK+ LG+ T NL++ +I
Sbjct: 581 YRNNRSSKCRAIIINNVVF--CGMEKRIGSDKDKKKLSKLFERLGYQSTSYDNLKSSEIL 638
Query: 484 RYIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKL 663
++Q ++ +H D L++ ++SHG+ G+LY D P + +LA KPK
Sbjct: 639 ETVRQFTQSNH--GDSLIITIMSHGDQGLLYGVDG--VPVQMLDIIDLMCTASLAKKPKW 694
Query: 664 FFIQACQG 687
C+G
Sbjct: 695 LMCVCCRG 702
>UniRef50_UPI0000F1EFFE Cluster: PREDICTED: hypothetical protein;
n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 277
Score = 62.5 bits (145), Expect = 1e-08
Identities = 37/105 (35%), Positives = 58/105 (55%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLS 552
L R G DS L K+L LGFSV + ++ AE+I + + +E + T +C + + S
Sbjct: 48 LCKRIGVKRDSRRLYKILSELGFSVDIRLDIEAEEIYQAFK--AESEQTVKECFVGIISS 105
Query: 553 HGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
HGE G+++ D + NL ++ + P + K KLF IQAC+G
Sbjct: 106 HGEEGVVFGCDG--RAVNLAEIYSCFRSPIMKDKSKLFLIQACRG 148
>UniRef50_Q16FR8 Cluster: Caspase-1; n=1; Aedes aegypti|Rep:
Caspase-1 - Aedes aegypti (Yellowfever mosquito)
Length = 283
Score = 61.7 bits (143), Expect = 3e-08
Identities = 41/116 (35%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Frame = +1
Query: 358 FEIHNLKSRTGTNVDSDSLSKVLRGLGF---SVTVLHNLRAEDINRYIQQISEMDHT--D 522
FE + R GT+ D + L VL LGF + V + +I R ++ E+D
Sbjct: 46 FEDTSYDERCGTHKDVERLFHVLPRLGFLKEDIHVYEDYSYGEIQRAAMKL-ELDEELHQ 104
Query: 523 NDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
DCL+V +L+HGE L A++ Y +FT ++AGKPKLF +QAC+G
Sbjct: 105 ADCLMVFILTHGEANDKLMAQNDSYNLYEFLEHFTPTALKSMAGKPKLFIVQACRG 160
>UniRef50_P51878 Cluster: Caspase-5 precursor (EC 3.4.22.58)
(CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III)
[Contains: Caspase-5 subunit p20; Caspase-5 subunit
p10]; n=25; Eutheria|Rep: Caspase-5 precursor (EC
3.4.22.58) (CASP-5) (ICH-3 protease) (TY protease)
(ICE(rel)-III) [Contains: Caspase-5 subunit p20;
Caspase-5 subunit p10] - Homo sapiens (Human)
Length = 418
Score = 61.7 bits (143), Expect = 3e-08
Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 7/130 (5%)
Frame = +1
Query: 319 NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ 498
+ R +A+I + F+ +L +R G + D + ++L+GLG++V NL A D+ ++
Sbjct: 174 DRRRLALIICNTKFD--HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 231
Query: 499 ISEM-DHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY-----YFTADKCPTLAGKP 657
+ +H +D + ++SHG L G+ KPD L Y F C +L KP
Sbjct: 232 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 291
Query: 658 KLFFIQACQG 687
K+ +QAC+G
Sbjct: 292 KVIIVQACRG 301
>UniRef50_P55865 Cluster: Caspase-1-A precursor; n=3; Xenopus|Rep:
Caspase-1-A precursor - Xenopus laevis (African clawed
frog)
Length = 386
Score = 61.7 bits (143), Expect = 3e-08
Identities = 41/136 (30%), Positives = 69/136 (50%), Gaps = 15/136 (11%)
Frame = +1
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS 504
+G+A+I +E FE NL R G VD D ++K+L LG+ V NL ++ + +++ +
Sbjct: 143 KGLALIICNEKFE--NLNERHGAKVDLDGMTKLLNELGYQVHPHTNLTKTEMVKVMKEFA 200
Query: 505 -EMDHTDNDCLLVAVLSHGELGMLYAKDT--------HYKPDNL------WYYFTADKCP 639
+ +H D+D + ++SHG+ + D+ Y+ NL + F C
Sbjct: 201 AQEEHADSDSTFIVLMSHGDRQGVCGTDSKKTEKEKGQYEVTNLLEIDEIFSTFNNVNCS 260
Query: 640 TLAGKPKLFFIQACQG 687
L KPK+ IQAC+G
Sbjct: 261 KLRNKPKVIIIQACRG 276
>UniRef50_UPI00015B59A2 Cluster: PREDICTED: similar to
ecdysone-inducible caspase, putative; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
ecdysone-inducible caspase, putative - Nasonia
vitripennis
Length = 438
Score = 61.3 bits (142), Expect = 3e-08
Identities = 42/149 (28%), Positives = 68/149 (45%), Gaps = 13/149 (8%)
Frame = +1
Query: 280 PVERYAHYYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLH 459
P R Y M N RG+ ++ + ++I L R D D+L+ + +GF V
Sbjct: 163 PQSRGIERYAMRSNPRGLVLMITNIDYKI--LDRRPSAKYDEDNLTNLFEEMGFRVIKYK 220
Query: 460 NLRAEDINRYIQQISEMDHTDN-DCLLVAVLSHGE----------LGMLYAKDTHYKP-- 600
NL +I + +++ S+M D + V + SHG G+ Y T+
Sbjct: 221 NLTGNEIKKKVREFSQMKELARVDSVFVIISSHGSGERGKQETEIQGIDYMLSTYESIFC 280
Query: 601 DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
++ FTA +CP+L KPK+F Q C+G
Sbjct: 281 TDIIDNFTAMQCPSLINKPKIFIFQTCRG 309
>UniRef50_O08736 Cluster: Caspase-12 precursor; n=12; Eutheria|Rep:
Caspase-12 precursor - Mus musculus (Mouse)
Length = 419
Score = 61.3 bits (142), Expect = 3e-08
Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 9/150 (6%)
Frame = +1
Query: 265 RYAKMPVERYAHYYNM--NHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLG 438
++ K+ ER Y + +A+I ++ F+ L R + D ++ ++L LG
Sbjct: 153 QFCKIKTERAKEIYPVMEKEGRTRLALIICNKKFDY--LFDRDNADTDILNMQELLENLG 210
Query: 439 FSVTVLHNLRAEDINRYIQQIS-EMDHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPD--- 603
+SV + NL A+++ + Q + +H +D + +SHG L G+ K + KPD
Sbjct: 211 YSVVLKENLTAQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLH 270
Query: 604 --NLWYYFTADKCPTLAGKPKLFFIQACQG 687
++ F C +L KPK+ +QAC+G
Sbjct: 271 DDTIFKIFNNSNCRSLRNKPKILIMQACRG 300
>UniRef50_UPI0000D56041 Cluster: PREDICTED: similar to CG7486-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7486-PB, isoform B - Tribolium castaneum
Length = 568
Score = 60.9 bits (141), Expect = 4e-08
Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Frame = +1
Query: 367 HNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAV 546
+ L+ R GT D D L R GF V +NL ++ R I+++ + + D L +++
Sbjct: 347 NKLELRIGTQYDRDKLEATFRQFGFKTIVENNLTHLEMLRKIEEVVQSVN-DESSLFISI 405
Query: 547 LSHGELGMLYAKDT-HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+SHG++G++Y ++ + P L+GKPK+ +Q+CQG
Sbjct: 406 MSHGDVGVVYGVNSCQVDVKAIKRVMCTKNRPHLSGKPKVLILQSCQG 453
>UniRef50_A3QVU6 Cluster: Initiator caspase; n=3; Culicidae|Rep:
Initiator caspase - Aedes aegypti (Yellowfever mosquito)
Length = 493
Score = 60.5 bits (140), Expect = 6e-08
Identities = 33/105 (31%), Positives = 55/105 (52%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLS 552
LK+R GT VD ++ + LG+ V+ N+ +I ++Q + + L++ +LS
Sbjct: 278 LKNRRGTEVDKTAILNLFTNLGYEPIVVENIPHLEIMNQVEQAVDRVEPHHCSLVICLLS 337
Query: 553 HGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
HG+ G +Y ++ P ++ L GKPKL F+QACQG
Sbjct: 338 HGQEGKVYGSNS--IPVSVKAIERKMAARKLTGKPKLLFVQACQG 380
>UniRef50_UPI0000D57084 Cluster: PREDICTED: similar to CG8091-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8091-PA - Tribolium castaneum
Length = 395
Score = 60.1 bits (139), Expect = 8e-08
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 6/134 (4%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y NRG +I N+ FE +R G VD +L ++ +GF V + NL ++I
Sbjct: 132 YKTRSRNRGQVLIINNMVFETERHITRRGAEVDERNLKELFEKMGFYVDLYRNLSRDEIK 191
Query: 484 RYIQQISEMDHTD-NDCLLVAVLSHGE----LGMLYAKDTH-YKPDNLWYYFTADKCPTL 645
+++ SE ++ + D V ++SHGE ++ D + + + F C
Sbjct: 192 TVVKKFSEKEYKEAPDMAFVIIMSHGEKIENKTVIIGSDGQAVEEEWIIMQFNNQSCSLF 251
Query: 646 AGKPKLFFIQACQG 687
KPK+ C+G
Sbjct: 252 RNKPKILIFNICRG 265
>UniRef50_UPI0000F2CF2D Cluster: PREDICTED: similar to
evolutionarily related interleukin-1beta converting
enzyme; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to evolutionarily related interleukin-1beta
converting enzyme - Monodelphis domestica
Length = 372
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Frame = +1
Query: 355 HFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQIS-EMDHTDNDC 531
+ E RTG VD + +L+ LG++V V +L + ++ +++ + +H +D
Sbjct: 139 NIEFTYYSERTGAEVDIKGMEGLLKDLGYTVDVQRDLTSSEMASELRKFAARQEHESSDS 198
Query: 532 LLVAVLSHGELGMLYAKDTHYK--PDNLWY-----YFTADKCPTLAGKPKLFFIQACQG 687
V ++SHG L + K+ H K PD L Y CP L KPK+ IQAC+G
Sbjct: 199 TFVVLMSHGILDAICGKN-HKKEEPDVLPYDTIFNILNTKNCPKLKDKPKVIIIQACRG 256
>UniRef50_Q7KHK9 Cluster: DREAM; n=2; Sophophora|Rep: DREAM -
Drosophila melanogaster (Fruit fly)
Length = 527
Score = 59.3 bits (137), Expect = 1e-07
Identities = 39/117 (33%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Frame = +1
Query: 340 IFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHT 519
IFNHE F+ N + R G+ D L L V V+ + I + ++ + D
Sbjct: 317 IFNHERFDNKN-EFRKGSAQDVKVLRATFEQLKCKVEVITDATLVTIKKTVRMLQTKDFE 375
Query: 520 DNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
D L++ +LSHG + AKD Y D+ F + TL KPKL F+QAC+G
Sbjct: 376 DKSALVLVILSHGTRHDQIAAKDDDYSLDDD-VVFPILRNRTLKDKPKLIFVQACKG 431
>UniRef50_P31944 Cluster: Caspase-14 precursor (EC 3.4.22.-)
(CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14
subunit 2]; n=14; Mammalia|Rep: Caspase-14 precursor (EC
3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1;
Caspase-14 subunit 2] - Homo sapiens (Human)
Length = 242
Score = 58.8 bits (136), Expect = 2e-07
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Frame = +1
Query: 376 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDND---CLLVAV 546
K+R G+ D D+L + R L F T+ + AE +++ + + D C V +
Sbjct: 27 KAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVL 86
Query: 547 LSHGELGMLYAKDTHY-KPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
++HG G L +D K +NL+ C L KPK++ IQAC+G
Sbjct: 87 MAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRG 134
>UniRef50_Q9NBW3 Cluster: Cysteine protease; n=4; melanogaster
subgroup|Rep: Cysteine protease - Drosophila
melanogaster (Fruit fly)
Length = 255
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = +1
Query: 340 IFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHT 519
I NHE F + +R G++ D ++L K L V V+ N D+ +++ S T
Sbjct: 42 ILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKRFT 101
Query: 520 DNDCLLVAVLSHGELG--MLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+ ++ +LSHG+ +L Y D+ F + PTL+GKPK+ +QAC+G
Sbjct: 102 QDAGFVLFILSHGDRKEKILACDHREYHLDDD-VLFPLFRNPTLSGKPKILIVQACKG 158
>UniRef50_Q4S1R8 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14764, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 58.0 bits (134), Expect = 3e-07
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Frame = +1
Query: 307 NMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINR 486
N R I+ E + L+ R G + D+ L K L +GF V + +L + +I
Sbjct: 9 NPGRQGRRAVIVSVGEFYPQVGLQRRPGASRDAKRLHKTLMKMGFKVDIHQDLSSGEIYE 68
Query: 487 YIQQISEMDHTDNDCLLVAVLSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKL 663
+Q E DC L + SHGE G +Y D + +++ YF +KC + K K+
Sbjct: 69 LFEQ--ESRRPVEDCFLAVLSSHGEEGCVYGWDGEPVQLSHIFAYFD-NKC--MEKKTKV 123
Query: 664 FFIQACQG 687
F IQAC+G
Sbjct: 124 FLIQACRG 131
>UniRef50_Q7QGN0 Cluster: ENSANGP00000018113; n=4; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018113 - Anopheles gambiae
str. PEST
Length = 214
Score = 57.6 bits (133), Expect = 4e-07
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 4/121 (3%)
Frame = +1
Query: 337 IIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFS-VTVLHNLRAEDINRYIQQISEMD 513
++F+H+ F+ + +R G+ D + + + + + N ++ R + +IS D
Sbjct: 5 LVFHHDQFK-NPKNNREGSANDMKQIKEFCQHYRCDRLDINENKTKAEVTRKMGEISRKD 63
Query: 514 HTDNDCLLVAVLSHGELG-MLYAKDTHYK--PDNLWYYFTADKCPTLAGKPKLFFIQACQ 684
T N CL+V ++SHG + AKD + D++ Y T+++ TL KPKLF +QAC+
Sbjct: 64 FTKNSCLIVFIMSHGSANDTIMAKDGQFYSFQDDVVEYCTSNR--TLNDKPKLFVLQACR 121
Query: 685 G 687
G
Sbjct: 122 G 122
>UniRef50_Q5BLH4 Cluster: Caspase c; n=4; Danio rerio|Rep: Caspase c
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 400
Score = 56.4 bits (130), Expect = 1e-06
Identities = 38/137 (27%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Frame = +1
Query: 307 NMNHNNRG-MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
N N+R +A++ N+ FE L R G D S+ +L+GLG++V L +L A+ +
Sbjct: 221 NEKSNDRTRLALLINNVEFEY--LNDRKGAERDELSMEMLLKGLGYTVVTLRDLTAQGML 278
Query: 484 RYIQQISEM-DHTDNDCLLVAVLSHGELGMLY--------AKDTHYKPDNLWYYFTADKC 636
++ ++ +H +D V ++SHG + +D + D ++ C
Sbjct: 279 VAMRDFAQREEHAHSDSCFVVLMSHGNARGIAGVSKQASDGEDDLFCIDEIFNCLNTPNC 338
Query: 637 PTLAGKPKLFFIQACQG 687
L KPK+ IQAC+G
Sbjct: 339 DGLRDKPKIILIQACRG 355
>UniRef50_Q5E9C1 Cluster: Caspase-4 precursor (EC 3.4.22.57)
(CASP-4) [Contains: Caspase-4 subunit 1; Caspase-4
subunit 2]; n=9; Eutheria|Rep: Caspase-4 precursor (EC
3.4.22.57) (CASP-4) [Contains: Caspase-4 subunit 1;
Caspase-4 subunit 2] - Bos taurus (Bovine)
Length = 377
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Frame = +1
Query: 268 YAKMPVERYAHYYNMNH--NNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGF 441
+ K+ ER Y + + +A+I + F+ ++ R G +D + ++L GLG+
Sbjct: 114 FLKLCKERAGEIYPIKERKDRTRLALIICNTEFD--HMPPRNGAALDILGMKQLLEGLGY 171
Query: 442 SVTVLHNLRAEDINRYIQQISEMD-HTDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWY 615
+V V L A D+ + + + + H +D + +SHG L G+ + +PD L Y
Sbjct: 172 TVEVEEKLTARDMESVLWKFAAREEHKSSDSTFLVFMSHGILDGICGTMHSEEEPDVLPY 231
Query: 616 -----YFTADKCPTLAGKPKLFFIQACQG 687
F C +L KPK+ +QAC+G
Sbjct: 232 DTIFRTFNNRNCLSLKDKPKVIIVQACRG 260
>UniRef50_UPI00015553DC Cluster: PREDICTED: similar to caspase-15;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
caspase-15 - Ornithorhynchus anatinus
Length = 237
Score = 54.0 bits (124), Expect = 5e-06
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = +1
Query: 376 KSRTGTNVDSDSLSKVLRGLGFSVTVLHN----LRAEDINRYIQQISEMDHTDNDCLLVA 543
K R+G D + L K L FSV + + +D+ + +I+ + + C LV
Sbjct: 14 KGRSGATEDIEKLRKHLAAFRFSVQECIDPDGKVILQDLREFRDKINGSPY-EMSCCLVI 72
Query: 544 VLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
++SHG G + KD + ++ F CP L KPK+F IQAC+G
Sbjct: 73 LMSHGVNGFIKGKDEKVVDLEEIFKLFNNANCPNLREKPKIFIIQACRG 121
>UniRef50_O42284 Cluster: Caspase-1; n=3; Gallus gallus|Rep:
Caspase-1 - Gallus gallus (Chicken)
Length = 283
Score = 53.6 bits (123), Expect = 7e-06
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = +1
Query: 370 NLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISE-MDHTDNDCLLVAV 546
+L+ R G VD ++K+L GLG++V + ++++ +++ ++ DH +D +
Sbjct: 54 HLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVF 113
Query: 547 LSHG-ELGMLYAKDTHYKP----DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+SHG G+ K + ++ F C L GKPK+ IQ C+G
Sbjct: 114 MSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRG 165
>UniRef50_Q3T2L0 Cluster: Caspase-15; n=11; Theria|Rep: Caspase-15 -
Bos taurus (Bovine)
Length = 368
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Frame = +1
Query: 376 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQI-SEMDHTDND--CLLVAV 546
K+R G + D + L+ F T+ + D+ I E++ +D C LV +
Sbjct: 152 KNRLGAHQDVQLMKDWLKECKFEPTLCIDPDKMDLLGKITSFRDELNEIKDDIGCCLVTL 211
Query: 547 LSHGELGMLYAKDTH-YKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+SHGE G + KD ++++ F CP L KPK+F IQAC+G
Sbjct: 212 MSHGEEGFIKMKDGEKVSLEDIFEMFNNKNCPALQEKPKIFIIQACRG 259
>UniRef50_UPI000065DDFC Cluster: CASP8 and FADD-like apoptosis
regulator precursor (Cellular FLICE-like inhibitory
protein) (c-FLIP) (Caspase-eight-related protein)
(Casper) (Caspase-like apoptosis regulatory protein)
(CLARP) (MACH-related inducer of toxicity) (MRIT)
(Caspase homolog) (C; n=1; Takifugu rubripes|Rep: CASP8
and FADD-like apoptosis regulator precursor (Cellular
FLICE-like inhibitory protein) (c-FLIP)
(Caspase-eight-related protein) (Casper) (Caspase-like
apoptosis regulatory protein) (CLARP) (MACH-related
inducer of toxicity) (MRIT) (Caspase homolog) (C -
Takifugu rubripes
Length = 472
Score = 52.8 bits (121), Expect = 1e-05
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Frame = +1
Query: 400 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ-ISEMDHTDNDCLLVAVLSHGELGMLY 576
D D L + + L F V V L I I++ I + +T+ D + ++S G L
Sbjct: 261 DGDLLEQTFKALQFRVVVHKWLGGHQILPAIKETIRQRQYTEGDAFVCCIISRGTSNHLL 320
Query: 577 AKD---THYKPDNLWYYFTADKCPTLAGKPKLFFIQ 675
D T D++ FTA CP LAGKPKL FIQ
Sbjct: 321 GTDSCITGLPVDSVSQQFTAKGCPALAGKPKLLFIQ 356
>UniRef50_A5JSK5 Cluster: Cysteine protease; n=2; Eukaryota|Rep:
Cysteine protease - Oryzias latipes (Medaka fish)
(Japanese ricefish)
Length = 319
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 25/153 (16%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
Y +N G+ +I N+++F ++ R GT D++SL++V LGF V + + ++ +
Sbjct: 58 YQLNTRPVGICVIINNQNFLDGSV--RRGTEKDAESLAEVFSWLGFRVLMCKDQTSDQMK 115
Query: 484 RYIQQISEMDH-TD-----------------------NDCLLVAVLSHGELGMLYAKDTH 591
++ +S + TD D + +LSHG+ GM+ D
Sbjct: 116 GTLECLSLLSSSTDLLKLQAQEWSESRYAGPQQALQHGDAFVCCILSHGQKGMVLGIDQM 175
Query: 592 YKP-DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
P ++ F A + L GKPK+F IQACQG
Sbjct: 176 PVPIKHITRIFKASEQSALTGKPKMFLIQACQG 208
>UniRef50_Q498I3 Cluster: LOC780745 protein; n=6; Xenopus|Rep:
LOC780745 protein - Xenopus laevis (African clawed frog)
Length = 512
Score = 52.4 bits (120), Expect = 2e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Frame = +1
Query: 400 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMD-HTDNDCLLVAVLSHGELGMLY 576
D+ L + L F+V E + ++ ++ M+ H ++D + ++S G ++
Sbjct: 306 DASLLENTFKSLRFTVRTDRYCNVEHLESILKDVANMEQHKNHDIFVCIIISRGTSNSIF 365
Query: 577 AKDT---HYKPDNLWYYFTADKCPTLAGKPKLFFIQ 675
D+ + D + + FT CP L GKPKLFF+Q
Sbjct: 366 CIDSCSLGFSLDRIKHIFTGKSCPDLLGKPKLFFVQ 401
>UniRef50_Q28XB8 Cluster: GA14832-PA; n=1; Drosophila
pseudoobscura|Rep: GA14832-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 196
Score = 51.6 bits (118), Expect = 3e-05
Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +1
Query: 340 IFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHT 519
IFNHE F+ + R G+ D +L K L + + + + I +I +
Sbjct: 6 IFNHETFKNDLHEPRIGSAKDVQALRKTFEKLQCQIIEIKDPTLAAVKEKISEIERKNFE 65
Query: 520 DNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
L++ +LSHG E M+ A D + K TL GKPK+ QAC+G
Sbjct: 66 QQSALIIVLLSHGGENEMIVASDNKEYSLHKDVLLPLFKNETLKGKPKILIAQACKG 122
>UniRef50_A6NFM5 Cluster: Uncharacterized protein ENSP00000371619;
n=11; Eutheria|Rep: Uncharacterized protein
ENSP00000371619 - Homo sapiens (Human)
Length = 408
Score = 51.2 bits (117), Expect = 4e-05
Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDN---DCLLVA 543
++ R G D ++L + LGF TV + A+ + Q E T C LVA
Sbjct: 165 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 224
Query: 544 VLSHG-ELGMLYAKD-THYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+++HG G L D +P+ L + +C L G+PK+F +QAC+G
Sbjct: 225 LMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLLQACRG 272
>UniRef50_O15519-8 Cluster: Isoform 8 of O15519 ; n=3;
Homo/Pan/Gorilla group|Rep: Isoform 8 of O15519 - Homo
sapiens (Human)
Length = 445
Score = 49.2 bits (112), Expect = 1e-04
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 400 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 576
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 228 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 287
Query: 577 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 675
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 288 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 323
>UniRef50_O15519 Cluster: CASP8 and FADD-like apoptosis regulator
precursor (Cellular FLICE-like inhibitory protein)
(c-FLIP) (Caspase-eight-related protein) (Casper)
(Caspase-like apoptosis regulatory protein) (CLARP)
(MACH-related inducer of toxicity) (MRIT) (Caspase
homolog) (CASH) (Inhibitor of FLICE) (I-FLICE)
(FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin)
[Contains: CASP8 and FADD-like apoptosis regulator
subunit p43; CASP8 and FADD-like apoptosis regulator
subunit p12]; n=46; Amniota|Rep: CASP8 and FADD-like
apoptosis regulator precursor (Cellular FLICE-like
inhibitory protein) (c-FLIP) (Caspase-eight-related
protein) (Casper) (Caspase-like apoptosis regulatory
protein) (CLARP) (MACH-related inducer of toxicity)
(MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE)
(I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1)
(Usurpin) [Contains: CASP8 and FADD-like apoptosis
regulator subunit p43; CASP8 and FADD-like apoptosis
regulator subunit p12] - Homo sapiens (Human)
Length = 480
Score = 49.2 bits (112), Expect = 1e-04
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Frame = +1
Query: 400 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEM-DHTDNDCLLVAVLSHGELGMLY 576
+++ L LG+ V +L I++ + Q + M +H D D + ++S G +Y
Sbjct: 263 ETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVY 322
Query: 577 AKD-TH--YKPDNLWYYFTADKCPTLAGKPKLFFIQ 675
D TH ++ F D CP LAGKPK+FFIQ
Sbjct: 323 GVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQ 358
>UniRef50_Q4RQQ1 Cluster: Chromosome 2 SCAF15004, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15004, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 407
Score = 47.2 bits (107), Expect = 6e-04
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Frame = +1
Query: 403 SDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQ-ISEMDHTDNDCLLVAVLSHGELGMLYA 579
SD L + R L FSV V LR +I +++ + + + T+ D ++S G L
Sbjct: 232 SDLLEQTFRALHFSVVVHRWLRGFEILTTLKETMRQRECTEGDVFACCIISRGTSNHLLG 291
Query: 580 KDTHYKP---DNLWYYFTADKCPTLAGKPKLFFI 672
D+H + +++ F A++C LAGKP+L F+
Sbjct: 292 TDSHNRGLHVNSIRRQFAANECLALAGKPRLLFL 325
>UniRef50_Q9XYF4 Cluster: Caspase Nc precursor (EC 3.4.22.-)
(NEDD2-like caspase DRONC) [Contains: Caspase Nc subunit
1; Caspase Nc subunit 2]; n=2; Sophophora|Rep: Caspase
Nc precursor (EC 3.4.22.-) (NEDD2-like caspase DRONC)
[Contains: Caspase Nc subunit 1; Caspase Nc subunit 2] -
Drosophila melanogaster (Fruit fly)
Length = 450
Score = 47.2 bits (107), Expect = 6e-04
Identities = 29/135 (21%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDI 480
Y + NRG+ ++ N + N + R G DS SL + + L F++ N+ +
Sbjct: 187 YKMQSRFNRGVLLMVNIMDYPDQN-RRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQF 245
Query: 481 NRYIQQISEMDHTDN-DCLLVAVLSHGEL-----GMLYAKDTHYKPDNLWYYFTADKCPT 642
+ + ++ + N +C ++ +++HG + + + + +F KCP
Sbjct: 246 FKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPY 305
Query: 643 LAGKPKLFFIQACQG 687
L KPK+ C+G
Sbjct: 306 LVNKPKVLMFPFCRG 320
>UniRef50_Q178B7 Cluster: Caspase-3; n=2; Aedes aegypti|Rep:
Caspase-3 - Aedes aegypti (Yellowfever mosquito)
Length = 391
Score = 46.4 bits (105), Expect = 0.001
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +1
Query: 337 IIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVT-VLHNLRAEDINRYIQQISEMD 513
++ H F+ + R G+ +D + + ++G + + + + + + +++ +
Sbjct: 181 VLIFHNIFKNNKQLHRKGSELDLKLIKEFVKGYNMKIADICEDFSVTKVKKKMNEVTLKN 240
Query: 514 HTDNDCLLVAVLSHGELG-MLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
L++ ++SHG L + + Y D T TL GKPKLFF+QAC+G
Sbjct: 241 FGSYSSLMIVIMSHGGLNDHIQTSNGFYHLDTTIVEPTLMN-ETLKGKPKLFFVQACKG 298
>UniRef50_UPI0000F2CF2F Cluster: PREDICTED: similar to caspase 12;
n=1; Monodelphis domestica|Rep: PREDICTED: similar to
caspase 12 - Monodelphis domestica
Length = 401
Score = 45.2 bits (102), Expect = 0.002
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Frame = +1
Query: 286 ERYAHYYNMNHNNRG-MAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHN 462
+R Y M +R +A+I + F+ +L+ D + + +L+ LG+ V V
Sbjct: 141 KREKMYLVMEKGSRTRLALIICNTKFD--HLQELNKAQFDIERMKDLLQILGYRVEVKKE 198
Query: 463 LRAEDINRYIQQIS-EMDHTDNDCLLVAVLSHGEL-GMLYAKDTHYKPD-----NLWYYF 621
L + D+ ++Q + +H +D + +S+G G+ K +PD ++ F
Sbjct: 199 LSSVDMESVLKQFALRQEHESSDSTFLIFMSYGTTTGICGIKHKQLEPDILANDTIFKIF 258
Query: 622 TADKCPTLAGKPKLFFIQACQ 684
C L KPK+ IQ CQ
Sbjct: 259 NNSNCSRLRNKPKIIIIQECQ 279
>UniRef50_UPI00015B57F0 Cluster: PREDICTED: similar to GA20532-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA20532-PA - Nasonia vitripennis
Length = 1390
Score = 44.8 bits (101), Expect = 0.003
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +1
Query: 517 TDNDCLLVAVLSHGEL-GMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
T++DC+ + + +HG G+L+AKD Y P + +L KPK+FFIQAC+G
Sbjct: 249 TNDDCICIFISTHGTSDGLLWAKDVCY-PFIRTFENRIASIKSLINKPKIFFIQACRG 305
>UniRef50_A7SXL6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 180
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 535 LVAVLSHGELGMLYAKDTHYKP-DNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+ ++SHG + D ++ D + F CP LA KPKLFFIQAC+G
Sbjct: 1 ICVIMSHGGKNGILTNDLNFVDVDEITGKFQGTNCPQLATKPKLFFIQACRG 52
>UniRef50_Q8IRY7 Cluster: Caspase-8 precursor (EC 3.4.22.61)
(Death-related Ced-3/NEDD2-like protein) [Contains:
Caspase-8 subunit p15; Caspase-8 subunit p10]; n=7;
Sophophora|Rep: Caspase-8 precursor (EC 3.4.22.61)
(Death-related Ced-3/NEDD2-like protein) [Contains:
Caspase-8 subunit p15; Caspase-8 subunit p10] -
Drosophila melanogaster (Fruit fly)
Length = 516
Score = 44.8 bits (101), Expect = 0.003
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Frame = +1
Query: 373 LKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVLS 552
L+ R GT+VD + L +V +G++V N+ I I+ + D L+V +LS
Sbjct: 308 LRRRDGTDVDKERLIEVFSSMGYNVEAYDNVDHMGIIERIRSACDRSLV-RDSLVVFILS 366
Query: 553 HGELGMLYAKDT-HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQ 684
HG +YA ++ K ++ + TL KPKL IQACQ
Sbjct: 367 HGFEEAVYASNSIAMKITDIEDLLCS--YDTLYYKPKLLIIQACQ 409
>UniRef50_UPI000155BC01 Cluster: PREDICTED: similar to cellular
FLICE-like inhibitory protein long form; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
cellular FLICE-like inhibitory protein long form -
Ornithorhynchus anatinus
Length = 508
Score = 44.4 bits (100), Expect = 0.004
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 4/97 (4%)
Frame = +1
Query: 400 DSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDN-DCLLVAVLSHGELGMLY 576
D++ L + LGF V E ++R ++ + + D ++S G G +
Sbjct: 293 DTERLKETFEALGFEVMTCPYPDVETLDRTLRDTARLPGLGACDSFACVLVSRGGPGTVL 352
Query: 577 AKDTHYKP---DNLWYYFTADKCPTLAGKPKLFFIQA 678
P L +FT D CP L GKPKLFFIQ+
Sbjct: 353 GVGPAGPPFPLRRLRTFFTGDACPALLGKPKLFFIQS 389
>UniRef50_A2I5C3 Cluster: Putative caspase 3; n=1; Mytilus
galloprovincialis|Rep: Putative caspase 3 - Mytilus
galloprovincialis (Mediterranean mussel)
Length = 56
Score = 44.4 bits (100), Expect = 0.004
Identities = 19/48 (39%), Positives = 28/48 (58%)
Frame = +1
Query: 544 VLSHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 687
+++HG ++ DT K + YF A+ C L KPK+F IQAC+G
Sbjct: 1 LMTHGNEEEVFLTDTSIKMKSFLSYFNAENCKELQLKPKIFIIQACRG 48
>UniRef50_A7M858 Cluster: Caspase-like protease; n=1; Suberites
domuncula|Rep: Caspase-like protease - Suberites
domuncula (Sponge)
Length = 477
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Frame = +1
Query: 313 NHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYI 492
N G+AII +++ +L + T T+ D ++ V R L ++V ++N+ +++ +
Sbjct: 14 NAKGYGLAIIITNDYRRAPDLSALTETHNDGKRIADVFRELNYAVFHMYNVSEHQLDQLL 73
Query: 493 QQISEMDHTDN--DCLLVAVLSHGE---------LGMLYAKDTHYKP-DNLWYYFTADKC 636
+ ++ ++V HG L LY +D P + F
Sbjct: 74 YEATQKSTYPRCYQSIVVVYSGHGSIQVINDQNSLTFLYTQDCFQYPIKEIVKCFMPSYS 133
Query: 637 PTLAGKPKLFFIQACQG 687
P + PK+F I AC G
Sbjct: 134 PKIGAMPKVFLIDACLG 150
>UniRef50_UPI0000DB7195 Cluster: PREDICTED: similar to caspase 10
isoform a preproprotein; n=1; Apis mellifera|Rep:
PREDICTED: similar to caspase 10 isoform a preproprotein
- Apis mellifera
Length = 247
Score = 40.7 bits (91), Expect = 0.051
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +1
Query: 475 DINRYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLAG 651
+I + ++ I + D DC+ V +LSHG E G++ A + K + + Y F + + L
Sbjct: 62 EILKMLEDIPKTFGVDYDCIFVCILSHGYEGGIISADEKEVKTEEIEYKFCSIE---LKD 118
Query: 652 KPKLFFIQACQG 687
K+ IQACQG
Sbjct: 119 VIKIVIIQACQG 130
>UniRef50_A5K522 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 830
Score = 39.1 bits (87), Expect = 0.15
Identities = 25/86 (29%), Positives = 37/86 (43%)
Frame = +1
Query: 163 DEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAII 342
D+ ++ NG E+ GN+DE D +H +S G A HY N +N+ +
Sbjct: 93 DQGEQENGQEEEENGQGNDDEDDDTSTHSNSSGSNNA-----HNGHYGNKKGSNK-IKKN 146
Query: 343 FNHEHFEIHNLKSRTGTNVDSDSLSK 420
NH + N + G N SD K
Sbjct: 147 SNHHYLRNLNAHNHNGNNNGSDENPK 172
>UniRef50_UPI0000E4A029 Cluster: PREDICTED: similar to PDZ domain
containing protein NHERF-2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to PDZ domain
containing protein NHERF-2 - Strongylocentrotus
purpuratus
Length = 792
Score = 37.5 bits (83), Expect = 0.47
Identities = 17/57 (29%), Positives = 29/57 (50%)
Frame = +1
Query: 304 YNMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE 474
Y M+ N+G+ I N+ F RTG++VD ++ V +G++ NL A+
Sbjct: 257 YPMDQRNKGLVFILNNYRFGPDRTTERTGSDVDLANVKHVFTEIGYTADEAQNLTAQ 313
>UniRef50_UPI0000587146 Cluster: PREDICTED: similar to caspase Xa;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to caspase Xa - Strongylocentrotus purpuratus
Length = 221
Score = 37.1 bits (82), Expect = 0.62
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 2/106 (1%)
Frame = +1
Query: 376 KSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDHTDNDCLLVAVL-S 552
K RTG+ VD ++ V +GF + +L AE + + + + C V +L
Sbjct: 3 KDRTGSEVDVRNIVHVFGEIGFEIETHSDLTAEQLKEKLGMFMKSPCHNGMCSAVFMLMG 62
Query: 553 HGELGMLYAKDTHYKPDNLWYYFTADK-CPTLAGKPKLFFIQACQG 687
HG + K H + +L + ++ GKPK+ F Q C+G
Sbjct: 63 HGNETGIECK--HKQIVSLEIIMKQIRGINSMIGKPKMIFFQCCRG 106
>UniRef50_Q54VI5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 324
Score = 31.9 bits (69), Expect(2) = 1.4
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +1
Query: 178 NNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNN 324
NN + N N + GS GS Y++ V R YNMN+NN
Sbjct: 46 NNNNNNNNNNNYNLNMNSTGGSGGSGSSYSYSRS-VNRNGVNYNMNYNN 93
Score = 23.0 bits (47), Expect(2) = 1.4
Identities = 9/35 (25%), Positives = 19/35 (54%)
Frame = +1
Query: 307 NMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDS 411
N N+NN + +N+ + H + S T N ++++
Sbjct: 114 NFNYNNNNNNLNYNYNNNNNHYIGSGTNNNNNNNN 148
>UniRef50_Q896Y6 Cluster: Putative uncharacterized protein; n=1;
Clostridium tetani|Rep: Putative uncharacterized protein
- Clostridium tetani
Length = 231
Score = 35.9 bits (79), Expect = 1.4
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +1
Query: 325 RGMAIIFNHE-HFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQI 501
+G+++ F H E+ L R G N SD + LR LGF+ L +L D NR+ +I
Sbjct: 33 QGVSVDFEQSLHQELDRLGYREGMNPSSDEMLVFLRNLGFTDKELIDLYQSDANRFNSKI 92
>UniRef50_Q03703 Cluster: Uncharacterized protein YML037C; n=2;
Saccharomyces cerevisiae|Rep: Uncharacterized protein
YML037C - Saccharomyces cerevisiae (Baker's yeast)
Length = 340
Score = 35.5 bits (78), Expect = 1.9
Identities = 16/53 (30%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 133 LLRFVIFKMADEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQG-RRYAKMPVE 288
L +FV+ ++ E+KK++G T++ K+ + WG GS G ++ ++ P+E
Sbjct: 187 LQKFVVKELPKEKKKSDGDKTKKNKSKRKSFFGFWGHSGSKSGSKKKSEKPIE 239
>UniRef50_Q638E4 Cluster: Membrane associated protein; n=11;
Bacillus cereus group|Rep: Membrane associated protein -
Bacillus cereus (strain ZK / E33L)
Length = 456
Score = 35.1 bits (77), Expect = 2.5
Identities = 19/75 (25%), Positives = 31/75 (41%)
Frame = +1
Query: 172 KKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAIIFNH 351
K+NNG G++Q+ GN+ E + S + G + E N G N+
Sbjct: 278 KENNGRGSQQKNRGNQQENNGRESQQGNNGNQQGNNGRESQQGNNGNQQGNNGRGSQGNN 337
Query: 352 EHFEIHNLKSRTGTN 396
H + +N + G N
Sbjct: 338 GHQQENNGRGSQGNN 352
>UniRef50_A0BJS7 Cluster: Chromosome undetermined scaffold_110,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_110,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 304
Score = 35.1 bits (77), Expect = 2.5
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +1
Query: 295 AHYYNMNHNNR-GMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRA 471
A+ N HNN G + H ++H L NV + L L + V + HN++
Sbjct: 194 ANGINQKHNNVFGRVTSVSPFHVQMHLLHILLIHNVMNSWLVVQLSKME-DVQIQHNVQM 252
Query: 472 EDINRYIQQISEMDHTDNDCLLVAV 546
+ + ++QQI++MDH +LV +
Sbjct: 253 QRLRMHVQQITQMDHVFGRIILVMI 277
>UniRef50_Q9UTJ8 Cluster: DNA repair protein rad50; n=1;
Schizosaccharomyces pombe|Rep: DNA repair protein rad50 -
Schizosaccharomyces pombe (Fission yeast)
Length = 1290
Score = 35.1 bits (77), Expect = 2.5
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Frame = +1
Query: 352 EHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINRYIQQISEMDH--TDN 525
E F +K++T T ++ L K + L ++ LH+++ +INR + ++ + + TD
Sbjct: 1088 ERFRRQLIKTKT-TGKANEDLGKYAKALDVAIMQLHSMKMNEINRIVDELWKQTYCGTDI 1146
Query: 526 DCLLVAVLSHGELGMLY 576
D +L+ S G+ Y
Sbjct: 1147 DTILIRSDSEGKGNRTY 1163
>UniRef50_Q7RPC2 Cluster: Putative uncharacterized protein PY01537;
n=2; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein PY01537 - Plasmodium yoelii yoelii
Length = 1022
Score = 34.7 bits (76), Expect = 3.3
Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Frame = +1
Query: 142 FVIFKMADEEKKNNGSGTEQRKNGNEDEGDAWG--SHGSSQGRRYAKMPVERYAHYYNMN 315
+ IFK DEE + + KN N DE D+ + +++ + ++ V YN N
Sbjct: 483 YSIFKDNDEENLAKSNFAKWFKNNNTDENDSGNLIKYLNNKNKTGTEIGVR-----YNNN 537
Query: 316 HNNRGMAIIFNHEHFEIHN--LKSRTGTNVDSDSLSKV 423
N + I NH E+++ L++ T TNV+++SL+ V
Sbjct: 538 GINGNLGTIPNHGASEMYSRVLENSTYTNVNNNSLNCV 575
>UniRef50_Q9U0J3 Cluster: Putative uncharacterized protein PFD0460c;
n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein PFD0460c - Plasmodium falciparum
(isolate 3D7)
Length = 1010
Score = 34.3 bits (75), Expect = 4.4
Identities = 21/75 (28%), Positives = 40/75 (53%)
Frame = +1
Query: 307 NMNHNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDINR 486
N N+NN I N + I+N+ S N+DS++++ + ++T+ ++I+R
Sbjct: 141 NENNNNINSNNIDNIDSNNINNIDSNNINNIDSNNINNI--DSNNNITIY-----DEIDR 193
Query: 487 YIQQISEMDHTDNDC 531
Y + E++H DN C
Sbjct: 194 YKIHMEEINHYDNFC 208
>UniRef50_Q8IEM2 Cluster: Protein phosphatase 2c-like protein,
putative; n=5; Plasmodium|Rep: Protein phosphatase
2c-like protein, putative - Plasmodium falciparum
(isolate 3D7)
Length = 827
Score = 33.9 bits (74), Expect = 5.8
Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 2/113 (1%)
Frame = +1
Query: 151 FKMADEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQG--RRYAKMPVERYAHYYNMNHNN 324
FK+ +EKKN+ T +KN D + + +S+G Y R ++ N+ N
Sbjct: 13 FKIKKKEKKNSIDDTHSQKNKYRDAINKYAQENNSRGECENYCDEYYSRRSNNTNIK-LN 71
Query: 325 RGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAEDIN 483
RGM N+ + ++ + +N+ SD + G S+ + +++N
Sbjct: 72 RGMKYSHNNNGLKKNDHFNCNNSNISSDENENNMND-GISINNIKQNNLDNVN 123
>UniRef50_O77033 Cluster: TRFA; n=2; Dictyostelium discoideum|Rep:
TRFA - Dictyostelium discoideum (Slime mold)
Length = 1390
Score = 33.9 bits (74), Expect = 5.8
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = +1
Query: 166 EEKKNNGSGTEQRKN--GNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNNRGMAI 339
E+ NG G + R N N D D+ + GR E Y N N+NN ++
Sbjct: 758 EKTSPNGDGRDNRDNIRDNRDNRDSRDGRDNRDGRDSRDRIQEYTREYNNNNNNNNSISS 817
Query: 340 IFNHEHFEIHNLKSRTGTNVDSDS 411
I N+ + +N + N ++++
Sbjct: 818 INNNNNNNNNNYNNNNNNNNNNNN 841
>UniRef50_O76627 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 177
Score = 33.9 bits (74), Expect = 5.8
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +1
Query: 196 EQRKNGNEDEGDAWGSHGSSQGRRYAKMPVERYAHYYNMNHNN 324
+QR N D G+HG+ QG R + V+ + ++ N N+NN
Sbjct: 134 KQRLRKNRGRYDPIGAHGAQQGTRGVQNEVQYHRNFQNNNNNN 176
>UniRef50_A4QWM4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 702
Score = 33.9 bits (74), Expect = 5.8
Identities = 15/38 (39%), Positives = 20/38 (52%)
Frame = +1
Query: 154 KMADEEKKNNGSGTEQRKNGNEDEGDAWGSHGSSQGRR 267
K+ADEE G G R++G D+ A +HGS R
Sbjct: 421 KLADEEHHEGGGGQRGRRHGGHDDKAAAAAHGSGSRSR 458
>UniRef50_Q5K5C1 Cluster: Caspase 7-like protein; n=1; Spodoptera
frugiperda ascovirus 1a|Rep: Caspase 7-like protein -
Spodoptera frugiperda ascovirus 1a
Length = 288
Score = 33.5 bits (73), Expect = 7.7
Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 4/133 (3%)
Frame = +1
Query: 301 YYNMNHNNRGMAIIFNHEHFEIHNLK-SRTGTNVDSDS--LSKVLRGLGFSVTVLHNLRA 471
YY+ + + II N + N S GT D D L L F V + N
Sbjct: 5 YYDTVGREKRLLII-NQRALALPNRTISSDGTCCDGDEYLLVDTFTKLNFKVQTIRNASK 63
Query: 472 EDINRYIQQISEMDHTDNDCLLVAVLSHG-ELGMLYAKDTHYKPDNLWYYFTADKCPTLA 648
+ ++ E + C V VL+ G + + D Y L+ FT T+
Sbjct: 64 IVLETTVRNYIEKNVKRVACYFVVVLNDGNDADTILTTDGTYSLSELYALFTLY---TVR 120
Query: 649 GKPKLFFIQACQG 687
PK+F IQ+C G
Sbjct: 121 AIPKVFLIQSCLG 133
>UniRef50_A0BZ43 Cluster: Chromosome undetermined scaffold_138,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_138,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 296
Score = 33.5 bits (73), Expect = 7.7
Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Frame = +1
Query: 316 HNNRGMAIIFNHEHFEIHNLKSRTGTNVDSDSLSKVLRGLGFSVTVLHNLRAE-DINRYI 492
H+ R IF+H+ +H+L++ N D K+L + ++ NLR + IN+++
Sbjct: 221 HSLRSTKPIFSHQENLLHSLRTLNLQNQKQDIQEKILLKIRLKQSIRSNLRKQPQINKFL 280
Query: 493 QQISEMDHTDN 525
+I N
Sbjct: 281 NKIKNNQEQKN 291
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 800,525,562
Number of Sequences: 1657284
Number of extensions: 15973256
Number of successful extensions: 43132
Number of sequences better than 10.0: 148
Number of HSP's better than 10.0 without gapping: 39426
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42787
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 83621356644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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