Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP02_F_A18
(875 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 137 4e-32
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 137 4e-32
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 137 4e-32
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 137 4e-32
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 137 4e-32
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 137 4e-32
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 137 4e-32
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 137 4e-32
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 137 6e-32
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 137 6e-32
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 137 6e-32
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 137 6e-32
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 137 6e-32
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 137 6e-32
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 137 6e-32
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 137 6e-32
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 137 6e-32
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 137 6e-32
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 137 6e-32
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 137 6e-32
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 137 6e-32
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 137 6e-32
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 137 6e-32
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 137 6e-32
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 137 6e-32
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 136 1e-31
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 136 1e-31
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 134 4e-31
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 131 3e-30
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 126 1e-28
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 126 1e-28
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 126 1e-28
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 126 1e-28
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 126 1e-28
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 126 1e-28
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 126 1e-28
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 126 1e-28
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 126 1e-28
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 126 1e-28
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 126 1e-28
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 126 1e-28
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 121 3e-27
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 121 3e-27
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 121 3e-27
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 121 3e-27
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 121 3e-27
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 120 5e-27
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 120 5e-27
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 120 5e-27
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 120 5e-27
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 120 5e-27
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 120 5e-27
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 120 9e-27
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 119 2e-26
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 118 2e-26
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 118 2e-26
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 118 3e-26
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 118 3e-26
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 118 3e-26
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 118 3e-26
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 118 3e-26
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 118 3e-26
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 118 3e-26
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 118 3e-26
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 118 3e-26
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 118 3e-26
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 118 4e-26
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 117 5e-26
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 117 5e-26
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 111 2e-24
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 111 2e-24
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 111 2e-24
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 111 2e-24
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 109 1e-23
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 99 2e-20
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 98 4e-20
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 98 4e-20
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 98 4e-20
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 98 4e-20
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 98 4e-20
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 93 9e-19
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 58 4e-08
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 33 1.0
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 33 1.0
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 33 1.0
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 33 1.0
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 33 1.0
Y00811-1|CAA68752.1| 750|Homo sapiens protein ( Human mRNA for ... 32 3.1
X07166-1|CAA30157.1| 743|Homo sapiens protein ( Human mRNA for ... 32 3.1
M26628-1|AAA52294.1| 750|Homo sapiens enkephalinase protein. 32 3.1
J03779-1|AAA51915.1| 750|Homo sapiens MME protein. 32 3.1
BC101658-1|AAI01659.1| 750|Homo sapiens membrane metallo-endope... 32 3.1
BC101632-1|AAI01633.1| 750|Homo sapiens membrane metallo-endope... 32 3.1
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 31 4.1
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 31 4.1
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 31 4.1
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 31 4.1
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 31 4.1
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 31 4.1
U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein. 31 5.5
BC101030-1|AAI01031.2| 770|Homo sapiens membrane metallo-endope... 31 5.5
BC101028-1|AAI01029.2| 622|Homo sapiens MMEL1 protein protein. 31 5.5
BC101027-1|AAI01028.2| 770|Homo sapiens membrane metallo-endope... 31 5.5
AL831784-1|CAI17336.1| 779|Homo sapiens mel transforming oncoge... 31 5.5
AL589746-1|CAI22652.1| 779|Homo sapiens mel transforming oncoge... 31 5.5
AF336981-1|AAL08942.1| 770|Homo sapiens neprilysin-like metallo... 31 5.5
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 137 bits (332), Expect = 4e-32
Identities = 62/120 (51%), Positives = 84/120 (70%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGL 581
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW ALEALV KGL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155
Query: 582 TRSIGLSNFNRRQIERVLEVAKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
+++GLSNFN RQI+ +L VA ++PAVLQ+E HPYL Q +L C++R + V S G+
Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+L L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 112 bits (270), Expect = 1e-24
Identities = 48/86 (55%), Positives = 65/86 (75%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKE 418
FI SKLW TF LV +A + + K+
Sbjct: 74 FIVSKLWPTFFERPLVRKAFEKTLKD 99
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 131 bits (317), Expect = 3e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 ILLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+L L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 112 bits (270), Expect = 1e-24
Identities = 48/86 (55%), Positives = 65/86 (75%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKE 418
FI SKLW TF LV +A + + K+
Sbjct: 74 FIVSKLWPTFFERPLVRKAFEKTLKD 99
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+L L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 112 bits (270), Expect = 1e-24
Identities = 48/86 (55%), Positives = 65/86 (75%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKE 418
FI SKLW TF LV +A + + K+
Sbjct: 74 FIVSKLWPTFFERPLVRKAFEKTLKD 99
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+L L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 112 bits (270), Expect = 1e-24
Identities = 48/86 (55%), Positives = 65/86 (75%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKE 418
FI SKLW TF LV +A + + K+
Sbjct: 74 FIVSKLWPTFFERPLVRKAFEKTLKD 99
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+L L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 112 bits (270), Expect = 1e-24
Identities = 48/86 (55%), Positives = 65/86 (75%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKE 418
FI SKLW TF LV +A + + K+
Sbjct: 74 FIVSKLWPTFFERPLVRKAFEKTLKD 99
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 137 bits (331), Expect = 6e-32
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 94 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 153
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 154 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 213
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 96
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 136 bits (329), Expect = 1e-31
Identities = 62/120 (51%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 61/120 (50%), Positives = 81/120 (67%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP F+ G + FP D +PS + +DTW A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 134 bits (324), Expect = 4e-31
Identities = 62/127 (48%), Positives = 82/127 (64%), Gaps = 2/127 (1%)
Frame = +3
Query: 390 RKLSRPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALV 569
RK LK+ L YLD+YLIHWPQ FK GDDLFPKD + I ++D W A+E LV
Sbjct: 90 RKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELV 149
Query: 570 EKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRG 743
++GL +++G+SNF+ QIE++L K KP Q+E HPYL QEKL ++C S+ I V
Sbjct: 150 DEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTA 209
Query: 744 LSXXGAP 764
S G+P
Sbjct: 210 YSPLGSP 216
Score = 116 bits (279), Expect = 1e-25
Identities = 54/116 (46%), Positives = 74/116 (63%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P++GLGTWKS G+V +AVK AID GYRH+DCA++Y NE EVG+A++ K +E +KRED+
Sbjct: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDL 73
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRRPVPEGLRG 508
FI SKLW TF LV +A + + K+P L G + G P+ +G
Sbjct: 74 FIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKG 129
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 131 bits (317), Expect = 3e-30
Identities = 61/120 (50%), Positives = 80/120 (66%), Gaps = 2/120 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L +L L+YLDLYLIHWP FK G + FP D +PS + +DT A+E LV++GL ++
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKA 156
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGAP 764
IG+SNFN Q+E +L K KPAV QIE HPYL QEKL ++C+S+ I V S G+P
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216
Score = 130 bits (315), Expect = 5e-30
Identities = 53/95 (55%), Positives = 72/95 (75%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
++ NNG P++GLGTWKS PG+VT+AVK AID+GYRH+DCAH+Y NE EVG A++ K
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 314 EGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
E +KRE++FI SKLWCT+H LV+ A + + +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSD 99
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 86 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 145
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 146 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 204
Score = 95.9 bits (228), Expect = 2e-19
Identities = 46/89 (51%), Positives = 63/89 (70%), Gaps = 5/89 (5%)
Frame = +2
Query: 164 VIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIK 328
V+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+R+K +G++K
Sbjct: 1 VLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 58
Query: 329 REDIFITSKLWCTFHRPDLVEEAIKTSXK 415
REDIF TSKLWC HRP+LV A++ S K
Sbjct: 59 REDIFYTSKLWCNSHRPELVRPALERSLK 87
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 69 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 128
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 129 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 187
Score = 63.7 bits (148), Expect = 8e-10
Identities = 27/45 (60%), Positives = 35/45 (77%)
Frame = +2
Query: 281 EVGDALRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
EVG A+R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 70
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 59/119 (49%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/99 (50%), Positives = 68/99 (68%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLK 104
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 116 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 175
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 176 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 234
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 21 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 78
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 79 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 117
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 57/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 105 bits (253), Expect = 2e-22
Identities = 62/141 (43%), Positives = 76/141 (53%), Gaps = 22/141 (15%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEG--------------------DDLFPKDSEDKFIP 521
R LK L L YLDLYLIHWP FK DL P D + IP
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDL-PLDESNMVIP 143
Query: 522 SAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQ 695
S D++DTW A+E LV GL ++IG+SNFN Q+ER+L + KP QIE HPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 696 EKLFEFCKSRDIAVRGLSXXG 758
+ L FC+SRD++V G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 105 bits (253), Expect = 2e-22
Identities = 62/141 (43%), Positives = 76/141 (53%), Gaps = 22/141 (15%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEG--------------------DDLFPKDSEDKFIP 521
R LK L L YLDLYLIHWP FK DL P D + IP
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDL-PLDESNMVIP 143
Query: 522 SAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQ 695
S D++DTW A+E LV GL ++IG+SNFN Q+ER+L + KP QIE HPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 696 EKLFEFCKSRDIAVRGLSXXG 758
+ L FC+SRD++V G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 105 bits (253), Expect = 2e-22
Identities = 62/141 (43%), Positives = 76/141 (53%), Gaps = 22/141 (15%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEG--------------------DDLFPKDSEDKFIP 521
R LK L L YLDLYLIHWP FK DL P D + IP
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDL-PLDESNMVIP 143
Query: 522 SAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQ 695
S D++DTW A+E LV GL ++IG+SNFN Q+ER+L + KP QIE HPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 696 EKLFEFCKSRDIAVRGLSXXG 758
+ L FC+SRD++V G
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 41.1 bits (92), Expect = 0.005
Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 19/71 (26%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFK--------EGDDL-----------FPKDSEDKFIPS 524
R LK L L YLDLYLIHWP FK +L P D + IPS
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPS 144
Query: 525 AVDYVDTWGAL 557
D++DTW L
Sbjct: 145 DTDFLDTWEIL 155
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 73.7 bits (173), Expect = 8e-13
Identities = 48/112 (42%), Positives = 58/112 (51%), Gaps = 22/112 (19%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEG--------------------DDLFPKDSEDKFIP 521
R LK L L YLDLYLIHWP FK DL P D + IP
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDL-PLDESNMVIP 143
Query: 522 SAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQI 671
S D++DTW A+E LV GL ++IG+SNFN Q+ER+L + KP QI
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 120 bits (290), Expect = 5e-27
Identities = 49/85 (57%), Positives = 65/85 (76%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKREDI 340
P +GL +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG +R K +EG ++RED+
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 341 FITSKLWCTFHRPDLVEEAIKTSXK 415
FI +KLWCT H+ LVE A + S K
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLK 89
Score = 73.7 bits (173), Expect = 8e-13
Identities = 48/112 (42%), Positives = 58/112 (51%), Gaps = 22/112 (19%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEG--------------------DDLFPKDSEDKFIP 521
R LK L L YLDLYLIHWP FK DL P D + IP
Sbjct: 85 RKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDL-PLDESNMVIP 143
Query: 522 SAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV--AKIKPAVLQI 671
S D++DTW A+E LV GL ++IG+SNFN Q+ER+L + KP QI
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 120 bits (288), Expect = 9e-27
Identities = 56/119 (47%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K +P Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ G+ H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 119 bits (286), Expect = 2e-26
Identities = 56/119 (47%), Positives = 75/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y DLYLIH+P + K G+++ PKD K + VD TW A+E + GL +S
Sbjct: 103 LKNLQLDYADLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFN R +E +L K +P Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 100 bits (240), Expect = 6e-21
Identities = 50/99 (50%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +AVK AI+ GY H+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAI 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLW HRP+LV A++ S K
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLK 104
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 118 bits (285), Expect = 2e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 118 bits (285), Expect = 2e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 88 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 147
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 148 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
Score = 97.1 bits (231), Expect = 7e-20
Identities = 48/120 (40%), Positives = 75/120 (62%), Gaps = 3/120 (2%)
Frame = +2
Query: 161 PVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRAKFEEGTIKR 331
PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+K +G++KR
Sbjct: 2 PVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKR 61
Query: 332 EDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRRPVPEGLRGQ 511
EDIF TSKLWCTF +P +V+ A+++S K+ + L+ G P+P+ G+
Sbjct: 62 EDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGK 121
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 101 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 160
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 161 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 218
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 126 PLPKDENGK 134
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 105 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 164
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 165 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 223
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 66
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 67 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 107
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (246), Expect = 1e-21
Identities = 50/100 (50%), Positives = 69/100 (69%), Gaps = 5/100 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAV 65
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
R+K +G++KREDIF TSKLWC HRP+LV A++ S K+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKK 105
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 99.1 bits (236), Expect = 2e-20
Identities = 47/98 (47%), Positives = 68/98 (69%), Gaps = 3/98 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ ++A+ K AI+ G+RH+D AH+Y NE++VG A+R+
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
K +G++KREDIF TSKLW T HRP+LV A++ S K+
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKK 105
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 58/118 (49%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L L+Y+DLYL+H+P A K G+ PKD K I VD TW +E + GL +S
Sbjct: 103 LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
IG+SNFN RQ+E +L K KP Q+E HPYLNQ KL +FCKS+DI + S G
Sbjct: 163 IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 101 bits (242), Expect = 3e-21
Identities = 51/129 (39%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAV---KDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ +AV K AI+ G+RH+D A++Y NE++VG A+R+
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPGFGVLGSLSDTLAPGLQGGRR 484
K +G++KREDIF TSKLWCTF +P +V+ A+++S K+ + L+ G
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 485 PVPEGLRGQ 511
P+P+ G+
Sbjct: 128 PLPKDENGK 136
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 118 bits (284), Expect = 3e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 103 bits (247), Expect = 8e-22
Identities = 52/101 (51%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++KREDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 118 bits (283), Expect = 4e-26
Identities = 55/119 (46%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LKNL L+Y+DLYLIH+P + K G+++ PKD K + VD TW A+E + L +S
Sbjct: 100 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKS 159
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNR +E +L ++KP Q+E HPY NQ KL +FCKS+DI + S G+
Sbjct: 160 IGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 218
Score = 100 bits (239), Expect = 8e-21
Identities = 49/99 (49%), Positives = 67/99 (67%), Gaps = 5/99 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVT-----QAVKDAIDIGYRHVDCAHIYLNEKEVGDAL 298
V N+G PV+G GT+ P EV +A K AI+ G+RH+D AH+Y NE++VG A+
Sbjct: 5 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 62
Query: 299 RAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
R+K +G++KREDIF TSKLWC HRP+L A++ S K
Sbjct: 63 RSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLK 101
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 117 bits (282), Expect = 5e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 101 bits (243), Expect = 3e-21
Identities = 51/101 (50%), Positives = 71/101 (70%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G+++REDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 117 bits (282), Expect = 5e-26
Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
LK L+Y+DLYLIH P + K G++L P D K I VD TW A+E + GL +S
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
IG+SNFNRRQ+E +L K KP Q+E HPY N+ KL +FCKS+DI + S G+
Sbjct: 163 IGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 101 bits (241), Expect = 5e-21
Identities = 51/101 (50%), Positives = 70/101 (69%), Gaps = 6/101 (5%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTW------KSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDA 295
V N+G PV+G GT+ +SK EVT K AI+ G+RH+D AH+Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 296 LRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
+R+K +G++ REDIF TSKLW TFHRP+LV A++ S K+
Sbjct: 65 IRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKK 105
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 111 bits (268), Expect = 2e-24
Identities = 52/118 (44%), Positives = 74/118 (62%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L+ L L+Y+DLY+I P AFK GD+++P+D K++ + TW A+EA + GL +S
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
+G+SNFNRRQ+E +L K KP Q+E HPY Q KL +FC+ DI + S G
Sbjct: 166 LGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 97.1 bits (231), Expect = 7e-20
Identities = 48/103 (46%), Positives = 67/103 (65%), Gaps = 4/103 (3%)
Frame = +2
Query: 119 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 286
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 287 GDALRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
G+A+R K EG ++REDIF KLW T H P++V ++ + +
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLR 107
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 111 bits (268), Expect = 2e-24
Identities = 52/118 (44%), Positives = 74/118 (62%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L+ L L+Y+DLY+I P AFK GD+++P+D K++ + TW A+EA + GL +S
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
+G+SNFNRRQ+E +L K KP Q+E HPY Q KL +FC+ DI + S G
Sbjct: 166 LGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 97.1 bits (231), Expect = 7e-20
Identities = 48/103 (46%), Positives = 67/103 (65%), Gaps = 4/103 (3%)
Frame = +2
Query: 119 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 286
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 287 GDALRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
G+A+R K EG ++REDIF KLW T H P++V ++ + +
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLR 107
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 111 bits (268), Expect = 2e-24
Identities = 52/118 (44%), Positives = 74/118 (62%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L+ L L+Y+DLY+I P AFK GD+++P+D K++ + TW A+EA + GL +S
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
+G+SNFNRRQ+E +L K KP Q+E HPY Q KL +FC+ DI + S G
Sbjct: 166 LGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 97.1 bits (231), Expect = 7e-20
Identities = 48/103 (46%), Positives = 67/103 (65%), Gaps = 4/103 (3%)
Frame = +2
Query: 119 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 286
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 287 GDALRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
G+A+R K EG ++REDIF KLW T H P++V ++ + +
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLR 107
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 111 bits (268), Expect = 2e-24
Identities = 52/118 (44%), Positives = 74/118 (62%), Gaps = 2/118 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRS 590
L+ L L+Y+DLY+I P AFK GD+++P+D K++ + TW A+EA + GL +S
Sbjct: 106 LRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
Query: 591 IGLSNFNRRQIERVLEV--AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
+G+SNFNRRQ+E +L K KP Q+E HPY Q KL +FC+ DI + S G
Sbjct: 166 LGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 97.1 bits (231), Expect = 7e-20
Identities = 48/103 (46%), Positives = 67/103 (65%), Gaps = 4/103 (3%)
Frame = +2
Query: 119 AAPVPVIFNNGRTCPVIGLGTW---KSKP-GEVTQAVKDAIDIGYRHVDCAHIYLNEKEV 286
AA + ++G + P+IGLGT+ KS P G +VK AID GYRH+D A+IY NE EV
Sbjct: 5 AASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 287 GDALRAKFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXK 415
G+A+R K EG ++REDIF KLW T H P++V ++ + +
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLR 107
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 109 bits (262), Expect = 1e-23
Identities = 48/91 (52%), Positives = 67/91 (73%), Gaps = 1/91 (1%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRAKFE 313
V+ + G+ P+IGLGTWKS+PG+V AVK A+ +GYRH+DCA IY NE E+G+AL+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 314 EG-TIKREDIFITSKLWCTFHRPDLVEEAIK 403
G + RE++F+TSKLW T H P+ VE A++
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALR 96
Score = 61.3 bits (142), Expect = 4e-09
Identities = 26/52 (50%), Positives = 35/52 (67%)
Frame = +3
Query: 402 RPRLKNLGLEYLDLYLIHWPQAFKEGDDLFPKDSEDKFIPSAVDYVDTWGAL 557
R L +L LEYLDLYL+HWP AF+ GD+ FPK+++ + Y +TW AL
Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 98.7 bits (235), Expect = 2e-20
Identities = 44/98 (44%), Positives = 68/98 (69%), Gaps = 3/98 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWKSKP---GEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G+ P++G GT ++ V +AV+ AID+GYRH+D A+ +LNE+ +G A+R
Sbjct: 9 VKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRK 68
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKE 418
K GT+KR+DIF T+K+W TF RP+LV+ ++ S K+
Sbjct: 69 KIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKK 106
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 97.9 bits (233), Expect = 4e-20
Identities = 46/100 (46%), Positives = 66/100 (66%), Gaps = 3/100 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPG 424
K +GT+KRE+IF T KLW TF R +LV A++ S K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLG 110
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 97.9 bits (233), Expect = 4e-20
Identities = 46/100 (46%), Positives = 66/100 (66%), Gaps = 3/100 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPG 424
K +GT+KRE+IF T KLW TF R +LV A++ S K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLG 110
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 97.9 bits (233), Expect = 4e-20
Identities = 46/100 (46%), Positives = 66/100 (66%), Gaps = 3/100 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPG 424
K +GT+KRE+IF T KLW TF R +LV A++ S K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLG 110
Score = 71.7 bits (168), Expect = 3e-12
Identities = 48/119 (40%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKE-GDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTR 587
LK LG +Y+DL++IH P A K+ G +L PKD+ + I V+ DTW LE ++ K
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTW-ELELILNKP--- 161
Query: 588 SIGLSNFNRRQIERVLEVAKIKPAVLQ-IEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
GL + KP Q +E HPYLNQ KL EFCKS+DI + S G+
Sbjct: 162 --GL---------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 97.9 bits (233), Expect = 4e-20
Identities = 46/100 (46%), Positives = 66/100 (66%), Gaps = 3/100 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPG 424
K +GT+KRE+IF T KLW TF R +LV A++ S K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLG 110
Score = 71.7 bits (168), Expect = 3e-12
Identities = 48/119 (40%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Frame = +3
Query: 411 LKNLGLEYLDLYLIHWPQAFKE-GDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTR 587
LK LG +Y+DL++IH P A K+ G +L PKD+ + I V+ DTW LE ++ K
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTW-ELELILNKP--- 161
Query: 588 SIGLSNFNRRQIERVLEVAKIKPAVLQ-IEVHPYLNQEKLFEFCKSRDIAVRGLSXXGA 761
GL + KP Q +E HPYLNQ KL EFCKS+DI + S G+
Sbjct: 162 --GL---------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 97.9 bits (233), Expect = 4e-20
Identities = 46/100 (46%), Positives = 66/100 (66%), Gaps = 3/100 (3%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK---SKPGEVTQAVKDAIDIGYRHVDCAHIYLNEKEVGDALRA 304
V N+G PV+G GT+ + + +A K AID+G+RH+D A++Y NE+EVG A+
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 305 KFEEGTIKREDIFITSKLWCTFHRPDLVEEAIKTSXKEPG 424
K +GT+KRE+IF T KLW TF R +LV A++ S K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLG 110
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 93.5 bits (222), Expect = 9e-19
Identities = 43/100 (43%), Positives = 61/100 (61%), Gaps = 2/100 (2%)
Frame = +3
Query: 465 AFKEGDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEV- 641
AFK GD+++P+D K++ + TW A+EA + GL +S+G+SNFNRRQ+E +L
Sbjct: 2 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 61
Query: 642 -AKIKPAVLQIEVHPYLNQEKLFEFCKSRDIAVRGLSXXG 758
K KP Q+E HPY Q KL +FC+ DI + S G
Sbjct: 62 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 101
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 58.0 bits (134), Expect = 4e-08
Identities = 27/59 (45%), Positives = 36/59 (61%)
Frame = +3
Query: 477 GDDLFPKDSEDKFIPSAVDYVDTWGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIK 653
G++L P D K I VD TW A+E + GL +SIG+SNFNRRQ+E +L +K
Sbjct: 2 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 33.5 bits (73), Expect = 1.0
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +3
Query: 120 PRQSPSYSTTDARVPSSD*ELGSLSRER*LKQSKTRSTSATGTWTAPTSTSMRRRWGTP* 299
P S YST D + D +L S + + + P ++ + + G P
Sbjct: 4780 PDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPA 4839
Query: 300 EPSLKKEQSKERISS*RPSYGARST 374
PS+K +Q +E +++ RP G ST
Sbjct: 4840 APSVKPQQQQEPLAAVRPPLGDLST 4864
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 33.5 bits (73), Expect = 1.0
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +3
Query: 120 PRQSPSYSTTDARVPSSD*ELGSLSRER*LKQSKTRSTSATGTWTAPTSTSMRRRWGTP* 299
P S YST D + D +L S + + + P ++ + + G P
Sbjct: 4780 PDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPA 4839
Query: 300 EPSLKKEQSKERISS*RPSYGARST 374
PS+K +Q +E +++ RP G ST
Sbjct: 4840 APSVKPQQQQEPLAAVRPPLGDLST 4864
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 33.5 bits (73), Expect = 1.0
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +3
Query: 120 PRQSPSYSTTDARVPSSD*ELGSLSRER*LKQSKTRSTSATGTWTAPTSTSMRRRWGTP* 299
P S YST D + D +L S + + + P ++ + + G P
Sbjct: 4780 PDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPA 4839
Query: 300 EPSLKKEQSKERISS*RPSYGARST 374
PS+K +Q +E +++ RP G ST
Sbjct: 4840 APSVKPQQQQEPLAAVRPPLGDLST 4864
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 33.5 bits (73), Expect = 1.0
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +3
Query: 120 PRQSPSYSTTDARVPSSD*ELGSLSRER*LKQSKTRSTSATGTWTAPTSTSMRRRWGTP* 299
P S YST D + D +L S + + + P ++ + + G P
Sbjct: 351 PDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPA 410
Query: 300 EPSLKKEQSKERISS*RPSYGARST 374
PS+K +Q +E +++ RP G ST
Sbjct: 411 APSVKPQQQQEPLAAVRPPLGDLST 435
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 33.5 bits (73), Expect = 1.0
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +3
Query: 120 PRQSPSYSTTDARVPSSD*ELGSLSRER*LKQSKTRSTSATGTWTAPTSTSMRRRWGTP* 299
P S YST D + D +L S + + + P ++ + + G P
Sbjct: 4780 PDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPA 4839
Query: 300 EPSLKKEQSKERISS*RPSYGARST 374
PS+K +Q +E +++ RP G ST
Sbjct: 4840 APSVKPQQQQEPLAAVRPPLGDLST 4864
>Y00811-1|CAA68752.1| 750|Homo sapiens protein ( Human mRNA for
common acute lymphocytic leukemia antigen CALLA (EC
3.4.24.11). ).
Length = 750
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 691 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
>X07166-1|CAA30157.1| 743|Homo sapiens protein ( Human mRNA for
enkephalinase (EC 3.4.24.11). ).
Length = 743
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 684 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 719
>M26628-1|AAA52294.1| 750|Homo sapiens enkephalinase protein.
Length = 750
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 691 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
>J03779-1|AAA51915.1| 750|Homo sapiens MME protein.
Length = 750
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 691 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
>BC101658-1|AAI01659.1| 750|Homo sapiens membrane
metallo-endopeptidase protein.
Length = 750
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 691 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
>BC101632-1|AAI01633.1| 750|Homo sapiens membrane
metallo-endopeptidase protein.
Length = 750
Score = 31.9 bits (69), Expect = 3.1
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEPG-FGVLGSLSDT 454
+++WC +RP+ +IKT PG F ++G+L ++
Sbjct: 691 AQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 31.5 bits (68), Expect = 4.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 546 WGALEALVEKGLTRSIGLSNFNRRQIERVLEVAKIKPAVLQIEV 677
W LE LV+ +IG S+ ++ Q+E++ + A++KP Q+ +
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein.
Length = 22
Score = 31.1 bits (67), Expect = 5.5
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 134 VIFNNGRTCPVIGLGTWK 187
++ NNG P++GLGTWK
Sbjct: 5 LLLNNGAKMPILGLGTWK 22
>BC101030-1|AAI01031.2| 770|Homo sapiens membrane
metallo-endopeptidase-like 1 protein.
Length = 770
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 711 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 748
>BC101028-1|AAI01029.2| 622|Homo sapiens MMEL1 protein protein.
Length = 622
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 563 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 600
>BC101027-1|AAI01028.2| 770|Homo sapiens membrane
metallo-endopeptidase-like 1 protein.
Length = 770
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 711 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 748
>AL831784-1|CAI17336.1| 779|Homo sapiens mel transforming
oncogene-like 1 protein.
Length = 779
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 720 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 757
>AL589746-1|CAI22652.1| 779|Homo sapiens mel transforming
oncogene-like 1 protein.
Length = 779
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 720 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 757
>AF336981-1|AAL08942.1| 770|Homo sapiens neprilysin-like
metallopeptidase 2 protein.
Length = 770
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +2
Query: 350 SKLWCTFHRPDLVEEAIKTSXKEP-GFGVLGSLSDTLA 460
+++WC +RP+ ++IKT P + VLGSL + A
Sbjct: 711 AQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAA 748
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,523,079
Number of Sequences: 237096
Number of extensions: 2390945
Number of successful extensions: 7847
Number of sequences better than 10.0: 116
Number of HSP's better than 10.0 without gapping: 6992
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7708
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11159604822
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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