Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP01_F_P02
(874 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F642 Cluster: Uridine 5'-monophosphate synthase; n=4;... 94 4e-18
UniRef50_Q01637 Cluster: Uridine 5'-monophosphate synthase (UMP ... 93 8e-18
UniRef50_Q7XZ31 Cluster: UMP synthase; n=1; Griffithsia japonica... 91 4e-17
UniRef50_P11172 Cluster: Uridine 5'-monophosphate synthase (UMP ... 85 2e-15
UniRef50_P13439 Cluster: Uridine 5'-monophosphate synthase (UMP ... 84 5e-15
UniRef50_Q6I6N9 Cluster: UMP synthase; n=1; Cyanidioschyzon mero... 82 2e-14
UniRef50_UPI0000DAE335 Cluster: hypothetical protein Rgryl_01000... 82 2e-14
UniRef50_Q4RNC5 Cluster: Chromosome 2 SCAF15014, whole genome sh... 82 2e-14
UniRef50_P09556 Cluster: Uridine 5'-monophosphate synthase (UMP ... 73 7e-12
UniRef50_O61790 Cluster: Putative uncharacterized protein; n=2; ... 73 1e-11
UniRef50_Q4QEW5 Cluster: Orotidine-5-phosphate decarboxylase/oro... 67 5e-10
UniRef50_Q18516 Cluster: Putative uncharacterized protein; n=2; ... 66 8e-10
UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;... 66 8e-10
UniRef50_A0RY85 Cluster: Orotate phosphoribosyltransferase; n=1;... 64 3e-09
UniRef50_Q0ID76 Cluster: PyrF/pyrE bifunctional enzyme; n=5; Syn... 61 3e-08
UniRef50_Q97CT9 Cluster: Orotate phosphoribosyltransferase; n=2;... 60 1e-07
UniRef50_Q9Z7U6 Cluster: Orotate phosphoribosyltransferase; n=5;... 60 1e-07
UniRef50_Q7NLP2 Cluster: Glr1079 protein; n=3; Cyanobacteria|Rep... 59 1e-07
UniRef50_A1RZB6 Cluster: Orotate phosphoribosyltransferase; n=1;... 59 2e-07
UniRef50_Q8YSY4 Cluster: Bifunctional enzyme pyrF/pyrE [Includes... 58 2e-07
UniRef50_Q25566 Cluster: Uridine 5'-monophosphate synthase (UMP ... 58 4e-07
UniRef50_Q9HM15 Cluster: Orotate phosphoribosyltransferase; n=3;... 57 7e-07
UniRef50_Q2IFH8 Cluster: Orotate phosphoribosyltransferase precu... 56 2e-06
UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;... 56 2e-06
UniRef50_Q8DHW5 Cluster: Orotate phosphoribosyltransferase; n=18... 55 2e-06
UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;... 55 3e-06
UniRef50_Q0W6Q2 Cluster: Orotate phosphoribosyltransferase; n=1;... 54 6e-06
UniRef50_A3DM49 Cluster: Orotate phosphoribosyltransferase; n=1;... 53 8e-06
UniRef50_Q9HNG2 Cluster: Orotate phosphoribosyltransferase; n=4;... 53 8e-06
UniRef50_O67742 Cluster: Orotate phosphoribosyltransferase; n=1;... 53 8e-06
UniRef50_Q8F1Z0 Cluster: Orotate phosphoribosyltransferase 1; n=... 53 1e-05
UniRef50_A0B8Q9 Cluster: Orotate phosphoribosyltransferase; n=1;... 53 1e-05
UniRef50_Q8YM41 Cluster: Orotate phosphoribosyltransferase; n=4;... 53 1e-05
UniRef50_Q74CN6 Cluster: Orotate phosphoribosyltransferase; n=8;... 52 1e-05
UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;... 52 1e-05
UniRef50_Q1MPM5 Cluster: Orotate phosphoribosyltransferase; n=2;... 52 2e-05
UniRef50_A7HGM2 Cluster: Orotate phosphoribosyltransferase; n=1;... 52 2e-05
UniRef50_Q7UYX5 Cluster: Orotate phosphoribosyltransferase; n=3;... 52 3e-05
UniRef50_Q6AJ35 Cluster: Probable orotate phosphoribosyltransfer... 51 3e-05
UniRef50_Q2LWJ4 Cluster: Orotate phosphoribosyltransferase; n=2;... 51 3e-05
UniRef50_A3H774 Cluster: Orotate phosphoribosyltransferase; n=1;... 51 3e-05
UniRef50_A7D434 Cluster: Orotate phosphoribosyltransferase; n=1;... 50 6e-05
UniRef50_O27888 Cluster: Orotate phosphoribosyltransferase; n=2;... 50 6e-05
UniRef50_Q89BL4 Cluster: Orotate phosphoribosyltransferase; n=11... 50 6e-05
UniRef50_UPI00015BB0AE Cluster: orotate phosphoribosyltransferas... 50 1e-04
UniRef50_A7DRA9 Cluster: Orotate phosphoribosyltransferase; n=1;... 48 2e-04
UniRef50_A3EQ68 Cluster: Orotate phosphoribosyltransferase; n=1;... 48 3e-04
UniRef50_Q55574 Cluster: Orotate phosphoribosyltransferase; n=9;... 48 3e-04
UniRef50_Q1PWC9 Cluster: Similar to orotate phosphoribosyl trans... 48 4e-04
UniRef50_Q9Y9D8 Cluster: Orotate phosphoribosyltransferase; n=1;... 48 4e-04
UniRef50_Q98AN7 Cluster: Orotate phosphoribosyltransferase 1; n=... 48 4e-04
UniRef50_Q58MW1 Cluster: Cyanobacterial orotate phosphoribosyltr... 47 7e-04
UniRef50_Q8NM11 Cluster: Orotate phosphoribosyltransferase; n=28... 47 7e-04
UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;... 46 0.001
UniRef50_P58859 Cluster: Orotate phosphoribosyltransferase; n=6;... 45 0.002
UniRef50_Q7VDR1 Cluster: Orotate phosphoribosyltransferase; n=7;... 44 0.004
UniRef50_Q8ZTG3 Cluster: Orotate phosphoribosyltransferase; n=5;... 44 0.004
UniRef50_A7M6E4 Cluster: Orotate phosphoribosyltransferase; n=1;... 43 0.009
UniRef50_Q6ACA3 Cluster: Orotate phosphoribosyltransferase; n=1;... 42 0.020
UniRef50_Q59049 Cluster: Adenine phosphoribosyltransferase; n=10... 42 0.020
UniRef50_UPI00015BCA71 Cluster: UPI00015BCA71 related cluster; n... 42 0.027
UniRef50_Q01WL5 Cluster: Orotate phosphoribosyltransferase; n=3;... 41 0.036
UniRef50_Q82EU1 Cluster: Orotate phosphoribosyltransferase; n=7;... 41 0.036
UniRef50_Q7NDF9 Cluster: Gll4276 protein; n=1; Gloeobacter viola... 41 0.047
UniRef50_O26962 Cluster: PyrE-like protein; n=3; Methanobacteria... 41 0.047
UniRef50_Q0W496 Cluster: Adenine phosphoribosyltransferase; n=7;... 40 0.062
UniRef50_Q45918 Cluster: Orotate phosphoribosyltransferase; n=2;... 40 0.062
UniRef50_Q6MP84 Cluster: PyrE protein; n=6; Bacteria|Rep: PyrE p... 40 0.083
UniRef50_Q6A910 Cluster: Orotate phosphoribosyltransferase; n=12... 40 0.11
UniRef50_Q6G463 Cluster: Orotate phosphoribosyltransferase; n=7;... 39 0.14
UniRef50_Q92SC6 Cluster: Orotate phosphoribosyltransferase; n=65... 39 0.14
UniRef50_A1SPW6 Cluster: Orotate phosphoribosyltransferase; n=3;... 39 0.19
UniRef50_Q74J27 Cluster: Orotate phosphoribosyltransferase; n=6;... 39 0.19
UniRef50_Q8KG85 Cluster: Orotate phosphoribosyltransferase; n=14... 38 0.33
UniRef50_A6C842 Cluster: Orotate phosphoribosyltransferase; n=1;... 38 0.33
UniRef50_A3WSJ9 Cluster: Orotate phosphoribosyltransferase; n=1;... 38 0.44
UniRef50_O28533 Cluster: Orotate phosphoribosyltransferase; n=1;... 38 0.44
UniRef50_A6G356 Cluster: Orotate phosphoribosyltransferase; n=1;... 37 0.58
UniRef50_Q6LX60 Cluster: Orotate phosphoribosyltransferase; n=7;... 37 0.58
UniRef50_Q1DNB0 Cluster: Orotate phosphoribosyltransferase; n=17... 37 0.58
UniRef50_Q97N11 Cluster: Orotate phosphoribosyltransferase; n=6;... 37 0.58
UniRef50_A3CS56 Cluster: PyrE-like protein; n=5; Methanomicrobia... 37 0.58
UniRef50_Q1ISH1 Cluster: Phosphoribosyltransferase; n=1; Acidoba... 37 0.77
UniRef50_Q1ATP7 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.0
UniRef50_Q66DQ2 Cluster: Adenine phosphoribosyltransferase; n=11... 36 1.0
UniRef50_Q3DVM1 Cluster: Phosphoribosyltransferase; n=2; Chlorof... 36 1.3
UniRef50_Q6F6Z6 Cluster: Orotate phosphoribosyltransferase; n=23... 36 1.3
UniRef50_Q2GDM5 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.8
UniRef50_Q0LJI1 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.8
UniRef50_Q0EY52 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.8
UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.8
UniRef50_A4TUN0 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.8
UniRef50_Q8ZJP7 Cluster: Orotate phosphoribosyltransferase; n=42... 36 1.8
UniRef50_Q5WX86 Cluster: Orotate phosphoribosyltransferase; n=4;... 35 2.3
UniRef50_Q3XYF1 Cluster: Orotate phosphoribosyl transferase; n=3... 35 2.3
UniRef50_A4SX83 Cluster: Adenine phosphoribosyltransferase; n=1;... 35 2.3
UniRef50_A1UNJ3 Cluster: Orotate phosphoribosyltransferase; n=6;... 35 2.3
UniRef50_UPI00006CB7C9 Cluster: Protein kinase domain containing... 35 3.1
UniRef50_Q7MSB1 Cluster: Putative uncharacterized protein; n=1; ... 35 3.1
UniRef50_A6PMI4 Cluster: Orotate phosphoribosyltransferase; n=1;... 35 3.1
UniRef50_Q1UZB0 Cluster: Orotate phosphoribosyltransferase; n=3;... 34 4.1
UniRef50_A5EY64 Cluster: Orotate phosphoribosyltransferase; n=1;... 34 4.1
UniRef50_A5JEM2 Cluster: Chloroplast RNA-polymerase sigma factor... 34 4.1
UniRef50_A1Z907 Cluster: CG8529-PE, isoform E; n=9; Diptera|Rep:... 34 4.1
UniRef50_Q2QAL5 Cluster: Orotate phosphoribosyltransferase-like ... 34 4.1
UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54... 34 4.1
UniRef50_Q5QYM7 Cluster: Orotate phosphoribosyltransferase; n=9;... 34 5.4
UniRef50_A7DHQ5 Cluster: Orotate phosphoribosyltransferase precu... 34 5.4
UniRef50_Q8UI98 Cluster: Orotate phosphoribosyltransferase; n=4;... 34 5.4
UniRef50_Q4HEY3 Cluster: Transformation system protein; n=12; Ca... 33 7.2
UniRef50_A1ZTS6 Cluster: Orotate phosphoribosyltransferase; n=1;... 33 7.2
UniRef50_Q16T77 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_A7I2M8 Cluster: Transformation system protein; n=1; Cam... 33 9.5
UniRef50_A7BCL9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_A3TGP0 Cluster: Putative uncharacterized protein; n=2; ... 33 9.5
UniRef50_A7AV27 Cluster: Orotate phosphoribosyltransferase; n=1;... 33 9.5
UniRef50_A2QTV9 Cluster: Contig An09c0090, complete genome; n=1;... 33 9.5
UniRef50_P21846 Cluster: Orotate phosphoribosyltransferase; n=7;... 33 9.5
UniRef50_P12426 Cluster: Adenine phosphoribosyltransferase; n=6;... 33 9.5
>UniRef50_Q2F642 Cluster: Uridine 5'-monophosphate synthase; n=4;
Endopterygota|Rep: Uridine 5'-monophosphate synthase -
Bombyx mori (Silk moth)
Length = 473
Score = 94.3 bits (224), Expect = 4e-18
Identities = 44/87 (50%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQL-IKXVHHXMICGVPYAALPLAVVISINTDRPM 225
+TP F LRVIVS+P +M S+ L L +K +CGVPY ALP+A ++SI +PM
Sbjct: 31 KTPAYFDLRVIVSYPDIMELTSNMLYDLAVKDSQFDHLCGVPYTALPIATLLSIQAKKPM 90
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+M+RKETK Y TKK +EG ++K+ TCL
Sbjct: 91 LMRRKETKSYGTKKSIEGHFKKDDTCL 117
Score = 91.5 bits (217), Expect = 3e-17
Identities = 45/108 (41%), Positives = 71/108 (65%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R++ ++Y +++ + KK L +EDV+TSG S+LETV+ L+ EGL+ T A I+L+R
Sbjct: 94 RKETKSYGTKKSI-EGHFKKDDTCLIIEDVITSGSSILETVKDLKNEGLVTTEAAIILDR 152
Query: 413 EQGGASVLEANGIAVKSLFTLTNLVRMLHKAGRIDNDTVELIFDHIKE 556
EQGG L NGI VKSLFT+ L+ +L K +I ++ V + +++ E
Sbjct: 153 EQGGRENLAKNGIHVKSLFTMRTLIEILKKHKKITDEIVVTVKNYLNE 200
>UniRef50_Q01637 Cluster: Uridine 5'-monophosphate synthase (UMP
synthase) (Rudimentary-like protein) [Includes: Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRTase);
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)
(OMPdecase)]; n=4; Diptera|Rep: Uridine 5'-monophosphate
synthase (UMP synthase) (Rudimentary-like protein)
[Includes: Orotate phosphoribosyltransferase (EC
2.4.2.10) (OPRTase); Orotidine 5'-phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)] - Drosophila
melanogaster (Fruit fly)
Length = 493
Score = 93.1 bits (221), Expect = 8e-18
Identities = 44/89 (49%), Positives = 64/89 (71%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
L VEDVVTSG S+L+TV L+ EG++VT AV+V++REQGG + + +G+ + SLFTL+ L
Sbjct: 121 LIVEDVVTSGSSILDTVRDLQGEGIVVTDAVVVVDREQGGVANIAKHGVRMHSLFTLSFL 180
Query: 485 VRMLHKAGRIDNDTVELIFDHIKECQFGT 571
+ LH+AGRI+ TVE + +I Q +
Sbjct: 181 LNTLHEAGRIEKSTVEAVAKYIAAVQINS 209
Score = 89.8 bits (213), Expect = 8e-17
Identities = 42/87 (48%), Positives = 58/87 (66%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISINTDRPM 225
+P+ F LRVIVS+P +M VS L + IK + +CGVPY ALPLA ++S+ PM
Sbjct: 35 SPVYFDLRVIVSYPDVMQTVSDLLVEHIKDKQLSAKHVCGVPYTALPLATIVSVQQGTPM 94
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+++RKE K Y TKKL+EG++ TCL
Sbjct: 95 LVRRKEAKAYGTKKLVEGIFNAGDTCL 121
>UniRef50_Q7XZ31 Cluster: UMP synthase; n=1; Griffithsia
japonica|Rep: UMP synthase - Griffithsia japonica (Red
alga)
Length = 257
Score = 90.6 bits (215), Expect = 4e-17
Identities = 37/86 (43%), Positives = 59/86 (68%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMI 228
++PI LR+ VS+P L+ ++ L+ I + H +CGVPY ALP A +S++ +PM+
Sbjct: 16 QSPIYIDLRLTVSYPSLLSQIASALQSCISSLPHDFLCGVPYTALPFATAMSVSNSKPML 75
Query: 229 MKRKETKLYATKKLLEGVYEKNQTCL 306
M+RKE K Y TK+++EG ++ +QTCL
Sbjct: 76 MRRKEQKSYGTKRIIEGDFKPHQTCL 101
Score = 75.4 bits (177), Expect = 2e-12
Identities = 40/98 (40%), Positives = 59/98 (60%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R K+Q + K + L VED+VTSG S++ETVE LR L V+HAV++++R
Sbjct: 77 RRKEQKSYGTKRIIEGDFKPHQTCLIVEDLVTSGMSIMETVEPLRNAQLTVSHAVVLIDR 136
Query: 413 EQGGASVLEANGIAVKSLFTLTNLVRMLHKAGRIDNDT 526
EQG L + I + S+FTL+ ++ +L A +ID DT
Sbjct: 137 EQGARDNLTEHQITLHSVFTLSEMLTVLVDADKIDTDT 174
>UniRef50_P11172 Cluster: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)]; n=21;
Eukaryota|Rep: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)] - Homo sapiens
(Human)
Length = 480
Score = 85.4 bits (202), Expect = 2e-15
Identities = 42/87 (48%), Positives = 63/87 (72%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
L +EDVVTSG S+LETVE L+KEGL VT A+++L+REQGG L+A+GI + S+ TL+ +
Sbjct: 120 LIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKM 179
Query: 485 VRMLHKAGRIDNDTVELIFDHIKECQF 565
+ +L + ++D +TV + I+E F
Sbjct: 180 LEILEQQKKVDAETVGRVKRFIQENVF 206
Score = 76.2 bits (179), Expect = 1e-12
Identities = 40/87 (45%), Positives = 52/87 (59%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISINTDRPM 225
+PI LR IVS P L+ V+ L Q + + +CGVPY ALPLA VI PM
Sbjct: 34 SPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPM 93
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+++RKETK Y TK+L+EG +TCL
Sbjct: 94 LIRRKETKDYGTKRLVEGTINPGETCL 120
>UniRef50_P13439 Cluster: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)]; n=34; cellular
organisms|Rep: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)] - Mus musculus
(Mouse)
Length = 481
Score = 83.8 bits (198), Expect = 5e-15
Identities = 42/92 (45%), Positives = 63/92 (68%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
L +EDVVTSG S+LETVE L+KEGL VT A+++L+REQGG L+A GI + ++ TL+ +
Sbjct: 120 LVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQM 179
Query: 485 VRMLHKAGRIDNDTVELIFDHIKECQFGTKDN 580
+ +L + +ID D V + I+E F ++
Sbjct: 180 LEILQQQEKIDADMVGRVKRFIQENVFSAANH 211
Score = 76.6 bits (180), Expect = 8e-13
Identities = 41/87 (47%), Positives = 52/87 (59%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISINTDRPM 225
+P+ LR IVS P L+ V+ L Q K + +CGVPY ALPLA VI PM
Sbjct: 34 SPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPM 93
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+++RKETK Y TK+L+EG QTCL
Sbjct: 94 LIRRKETKDYGTKRLVEGEINPGQTCL 120
>UniRef50_Q6I6N9 Cluster: UMP synthase; n=1; Cyanidioschyzon
merolae|Rep: UMP synthase - Cyanidioschyzon merolae (Red
alga)
Length = 463
Score = 82.2 bits (194), Expect = 2e-14
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R L +EDVVTSG S+LE V LR EGL V HA+++L+REQGG L GI ++S+F ++
Sbjct: 111 RCLIIEDVVTSGSSILEVVGALRAEGLKVDHAIVLLDREQGGCEALLGQGIGLRSVFRIS 170
Query: 479 NLVRMLHKAGRIDNDTVELIFDHIK 553
+LV L ++ V++I D I+
Sbjct: 171 DLVGTLRNLNLLEPGKVDMILDFIR 195
Score = 64.9 bits (151), Expect = 3e-09
Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVH--HXMICGVPYAALPLAVVISINTDRPM 225
+P LRV VS+P ++ +++ + ++ +ICGVPY ALP A +++ D PM
Sbjct: 27 SPFYVDLRVAVSYPRVLRSIAALYLECLQDFSGAFDVICGVPYTALPFATAMAVQGDLPM 86
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+M RKE K + T++++EG + + CL
Sbjct: 87 VMCRKEVKDHGTRRVVEGAFTQGSRCL 113
>UniRef50_UPI0000DAE335 Cluster: hypothetical protein
Rgryl_01000050; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000050 - Rickettsiella
grylli
Length = 183
Score = 81.8 bits (193), Expect = 2e-14
Identities = 39/85 (45%), Positives = 54/85 (63%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
+PI R ++S P L+ AVS L IK V ++CGVPY ALP+A IS+ + PM++
Sbjct: 29 SPIYIDCRSLISDPSLLRAVSVALWNKIKPVKPNLLCGVPYTALPMATTISLEQNLPMLI 88
Query: 232 KRKETKLYATKKLLEGVYEKNQTCL 306
RKE K Y TKK +EG+++ Q CL
Sbjct: 89 CRKEIKNYGTKKQVEGIFQVGQNCL 113
Score = 59.3 bits (137), Expect = 1e-07
Identities = 26/64 (40%), Positives = 42/64 (65%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+ L +EDVVT+G S+L +E L+ GL VT V +++REQGG ++A G + S++TL
Sbjct: 110 QNCLMIEDVVTTGSSVLHVIEVLKNHGLHVTDIVALVDREQGGKETIKAAGCQLHSVYTL 169
Query: 476 TNLV 487
++
Sbjct: 170 NEIL 173
>UniRef50_Q4RNC5 Cluster: Chromosome 2 SCAF15014, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15014, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 605
Score = 81.8 bits (193), Expect = 2e-14
Identities = 39/87 (44%), Positives = 56/87 (64%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISINTDRPM 225
TPI LRV+VSHP LM + + Q ++ + +CGVPY ALPLA +IS PM
Sbjct: 32 TPIYIDLRVLVSHPALMNQICGLIHQRMQEEDLRLDSVCGVPYTALPLATIISSKHLHPM 91
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+++RKE K Y T++L+EG + + +TCL
Sbjct: 92 LIRRKEAKDYGTRRLVEGTFREGETCL 118
Score = 37.9 bits (84), Expect = 0.33
Identities = 20/51 (39%), Positives = 27/51 (52%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIV 385
R K+ R ++ + L +ED VT+G S+LET E L KEGL V
Sbjct: 94 RRKEAKDYGTRRLVEGTFREGETCLIIEDTVTTGSSILETAEVLHKEGLKV 144
>UniRef50_P09556 Cluster: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)]; n=2;
Dictyostelium discoideum|Rep: Uridine 5'-monophosphate
synthase (UMP synthase) [Includes: Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRTase);
Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23)
(OMPdecase)] - Dictyostelium discoideum (Slime mold)
Length = 478
Score = 73.3 bits (172), Expect = 7e-12
Identities = 36/84 (42%), Positives = 53/84 (63%)
Frame = +2
Query: 287 KKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSL 466
K+ L VED+VTSG S+LETV L GL VT V++L+R++G LE G + S+
Sbjct: 112 KEGDNVLVVEDLVTSGASVLETVRDLNSVGLKVTDVVVLLDRQEGARQALEKQGYRLHSV 171
Query: 467 FTLTNLVRMLHKAGRIDNDTVELI 538
FT+ L+ L +AG++ T+EL+
Sbjct: 172 FTMEELINTLIEAGKLTGRTLELV 195
Score = 70.9 bits (166), Expect = 4e-11
Identities = 35/90 (38%), Positives = 55/90 (61%), Gaps = 5/90 (5%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHX-----MICGVPYAALPLAVVISINTD 216
+PI LRV VS P L+ A++ + Q + + ++CGVPY ALP+A +SI +
Sbjct: 29 SPIYIDLRVTVSSPPLLAAIAEMMYQKVYKSGNAQETPALVCGVPYTALPIATGMSIANN 88
Query: 217 RPMIMKRKETKLYATKKLLEGVYEKNQTCL 306
PM+++RKE K Y TK+L+EG +++ L
Sbjct: 89 IPMVVRRKEAKAYGTKQLIEGRFKEGDNVL 118
>UniRef50_O61790 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 227
Score = 72.9 bits (171), Expect = 1e-11
Identities = 39/87 (44%), Positives = 55/87 (63%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLM-VAVSHQLEQLI-KXVHHXMICGVPYAALPLAVVISINTDRPM 225
TPI LR I+S P ++ +A E+++ + + GVPYAALPLA ++S + PM
Sbjct: 56 TPIYIDLRRIMSSPRVLRMAAQAMCEKIVASNLKFDYVVGVPYAALPLATLVSDILNVPM 115
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
+MKRKE K Y TK+L+EGVY+ T L
Sbjct: 116 LMKRKEAKAYGTKQLIEGVYQPGGTVL 142
Score = 56.8 bits (131), Expect = 7e-07
Identities = 30/82 (36%), Positives = 45/82 (54%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
L VEDVVTSG S+ ET E +R E L+VT A+ VL+R+QG + L + + S T+ +
Sbjct: 142 LLVEDVVTSGESIRETAEAIRNENLLVTDAIAVLDRQQGATANLAEDNLNFLSFLTMEKI 201
Query: 485 VRMLHKAGRIDNDTVELIFDHI 550
+ L + + I H+
Sbjct: 202 LDGLITKNEMTEERKHEIIAHL 223
>UniRef50_Q4QEW5 Cluster: Orotidine-5-phosphate
decarboxylase/orotate phosphoribosyltransferase,
putative; n=23; Eukaryota|Rep: Orotidine-5-phosphate
decarboxylase/orotate phosphoribosyltransferase,
putative - Leishmania major
Length = 457
Score = 67.3 bits (157), Expect = 5e-10
Identities = 31/80 (38%), Positives = 50/80 (62%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
+PI LR +V++P +M V+ + ++++ I G+PYAALP+A IS + P+I
Sbjct: 284 SPIYIDLRRLVTYPAIMRLVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIY 343
Query: 232 KRKETKLYATKKLLEGVYEK 291
R+E K+Y TK +EG Y+K
Sbjct: 344 PRREAKIYGTKAAIEGEYKK 363
>UniRef50_Q18516 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 497
Score = 66.5 bits (155), Expect = 8e-10
Identities = 33/84 (39%), Positives = 52/84 (61%), Gaps = 3/84 (3%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISIN-TDRP 222
+PI LR HP L++ +S + + ++ V + + G+PYAALP A V + N +P
Sbjct: 40 SPIYIDLRECFGHPGLLMLISEAISKQVEISEVQYAGVLGIPYAALPYASVAAGNYLKKP 99
Query: 223 MIMKRKETKLYATKKLLEGVYEKN 294
+++ RKE K Y TKKL+EG+Y+ N
Sbjct: 100 LLIVRKEAKSYGTKKLIEGLYQPN 123
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/75 (36%), Positives = 46/75 (61%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R + +EDVVT+GGS+L+ V+ L E L+ + +L+REQGG L+ G+ + SL +
Sbjct: 125 RLILIEDVVTTGGSILDVVKVLHTENLVASDVFCILDREQGGRQKLQDAGVTLHSLLDMQ 184
Query: 479 NLVRMLHKAGRIDND 523
++ L+ G I ++
Sbjct: 185 TVLTFLYSTGAIGDE 199
>UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;
Sulfolobaceae|Rep: Orotate phosphoribosyltransferase -
Sulfolobus acidocaldarius
Length = 197
Score = 66.5 bits (155), Expect = 8e-10
Identities = 30/85 (35%), Positives = 57/85 (67%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
K+ + V+DV T+GGS+L+ VE +RK G V HA+++++RE+G LE+ GI + S++ +
Sbjct: 106 KKVIVVDDVATTGGSILKAVEEVRKAGGKVEHALVIVDREEGAFEKLESVGIRLLSVYKV 165
Query: 476 TNLVRMLHKAGRIDNDTVELIFDHI 550
+ ++ L K+ + + +LI D++
Sbjct: 166 SEILNSLIKSNLVAENEKKLISDYM 190
Score = 43.6 bits (98), Expect = 0.007
Identities = 23/75 (30%), Positives = 38/75 (50%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
+P LR + +HP + V ++K ++ MI GV +P A I+ ++PM
Sbjct: 26 SPYYLDLRKLPNHPDIFSFVVSSAVDIVKGINFDMILGVVTGGVPFASFIACKLNKPMGY 85
Query: 232 KRKETKLYATKKLLE 276
R E K + T++LLE
Sbjct: 86 IRAEKKGHGTERLLE 100
>UniRef50_A0RY85 Cluster: Orotate phosphoribosyltransferase; n=1;
Cenarchaeum symbiosum|Rep: Orotate
phosphoribosyltransferase - Cenarchaeum symbiosum
Length = 200
Score = 64.5 bits (150), Expect = 3e-09
Identities = 32/80 (40%), Positives = 46/80 (57%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
RAL ++DV T+GGS++ E+LR G IVT A +V++R +G L A GI + L
Sbjct: 116 RALIIDDVATTGGSVIRAAESLRAAGAIVTDAFVVIDRMEGAEGRLGAEGIKLHRLAGAL 175
Query: 479 NLVRMLHKAGRIDNDTVELI 538
+ R LH AG I D + +
Sbjct: 176 EVARSLHAAGLIPGDVMRQV 195
Score = 34.3 bits (75), Expect = 4.1
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVA-VSHQLEQLIKXV---HHXMICGVPYAALPLAVVISINTD 216
R+P F LR + SHP + L+ +I V + +P L +A ++I
Sbjct: 29 RSPYYFDLRSVPSHPHQFRGMIRGLLDSVISEVGLDRFDTLASIPTGGLVVASALAIEAV 88
Query: 217 RPMIMKRKETKLYATKKLLEGV 282
+P++ R K + T + +EG+
Sbjct: 89 KPLVYARAAAKGHGTGRTVEGI 110
>UniRef50_Q0ID76 Cluster: PyrF/pyrE bifunctional enzyme; n=5;
Synechococcus|Rep: PyrF/pyrE bifunctional enzyme -
Synechococcus sp. (strain CC9311)
Length = 484
Score = 61.3 bits (142), Expect = 3e-08
Identities = 27/77 (35%), Positives = 46/77 (59%)
Frame = +1
Query: 70 LRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETK 249
LR I+S P L V Q+++ + I G+PY +LP A +S+ +P+I RKE K
Sbjct: 320 LRQIISDPALFHRVLDCYAQVLRPLRFDRIAGIPYGSLPTATGLSLQLHKPLIYPRKEVK 379
Query: 250 LYATKKLLEGVYEKNQT 300
+ T++++EG ++K +T
Sbjct: 380 AHGTRRMVEGEFKKGET 396
Score = 41.1 bits (92), Expect = 0.036
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 287 KKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE----REQGGASVLEANGIA 454
KK + V+D++ +GGS++E + L GL V V+ L+ + L+++G+
Sbjct: 392 KKGETVAVVDDILITGGSVMEGISKLESSGLNVRDVVVFLDHGGIHDLRAKQRLQSHGVK 451
Query: 455 VKSLFTLTNLVRMLHKAGRIDNDTVE 532
++++ TL + +L + RI D +
Sbjct: 452 LQAVLTLDTISHVLETSDRISPDQAQ 477
>UniRef50_Q97CT9 Cluster: Orotate phosphoribosyltransferase; n=2;
Euryarchaeota|Rep: Orotate phosphoribosyltransferase -
Thermoplasma volcanium
Length = 166
Score = 59.7 bits (138), Expect = 1e-07
Identities = 26/60 (43%), Positives = 42/60 (70%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNLVR 490
+EDVVT+G S+L+ + LR+ G++V A V++RE+GGA +LE NGI + + ++ L R
Sbjct: 107 IEDVVTTGNSVLKAINVLRENGVVVKDAYCVVDREEGGAKLLENNGIKLHPIVRISELKR 166
Score = 33.5 bits (73), Expect = 7.2
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 109 VSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKLLEG 279
+S + K +H I G+ A+PL V S+N P ++ RKE + + T L+ G
Sbjct: 41 LSEIASEFSKMIHARKIAGMELGAVPLIVATSLNMGIPYVIVRKE-RSHGTLSLIVG 96
>UniRef50_Q9Z7U6 Cluster: Orotate phosphoribosyltransferase; n=5;
Chlamydophila|Rep: Orotate phosphoribosyltransferase -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 210
Score = 59.7 bits (138), Expect = 1e-07
Identities = 29/87 (33%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
TP+ +R+++S P ++ V+ + +L + ++CGVPY AL LA IS+ + PM++
Sbjct: 36 TPLYVDMRLVISSPEVLQTVATLIWRLRPSFNSSLLCGVPYTALTLATSISLKYNIPMVL 95
Query: 232 KRKETKLYATKKLL--EGVYEKNQTCL 306
+RKE + + EG++ QTCL
Sbjct: 96 RRKELQNVDPSDAIKVEGLFTPGQTCL 122
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/77 (33%), Positives = 45/77 (58%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
L + D+V+SG S++ET L + GL+V A++ L+R + L GI V S+FT+ L
Sbjct: 122 LVINDMVSSGKSIIETAVALEENGLVVREALVFLDRRKEACQPLGPQGIKVSSVFTVPTL 181
Query: 485 VRMLHKAGRIDNDTVEL 535
++ L G++ + + L
Sbjct: 182 IKALIAYGKLSSGDLTL 198
>UniRef50_Q7NLP2 Cluster: Glr1079 protein; n=3; Cyanobacteria|Rep:
Glr1079 protein - Gloeobacter violaceus
Length = 484
Score = 59.3 bits (137), Expect = 1e-07
Identities = 26/82 (31%), Positives = 46/82 (56%)
Frame = +1
Query: 55 PISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMK 234
P LR I+S+P L V +++ + I G+PY +LP A ++++ +RP+I
Sbjct: 315 PYYIDLRRIISNPQLFQQVLLAYAEILSTLSFDRIAGIPYGSLPTATGLALHLNRPLIFP 374
Query: 235 RKETKLYATKKLLEGVYEKNQT 300
RKE K + T++ +EG + +T
Sbjct: 375 RKEVKAHGTRRAIEGTFYPGET 396
Score = 47.6 bits (108), Expect = 4e-04
Identities = 20/70 (28%), Positives = 40/70 (57%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNLVR 490
++D++ +G S +E L+ GL+V V+++E ++ L++ G ++ + R
Sbjct: 400 IDDILITGNSAVEGARKLQSVGLVVRDIVVLIEHGPEASAFLQSQGYNAYAVLPFERIAR 459
Query: 491 MLHKAGRIDN 520
LH+AGRID+
Sbjct: 460 TLHQAGRIDD 469
>UniRef50_A1RZB6 Cluster: Orotate phosphoribosyltransferase; n=1;
Thermofilum pendens Hrk 5|Rep: Orotate
phosphoribosyltransferase - Thermofilum pendens (strain
Hrk 5)
Length = 173
Score = 58.8 bits (136), Expect = 2e-07
Identities = 29/85 (34%), Positives = 52/85 (61%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R +K+ + + Y + +K L V+DV T+GG+LL+ L+ EGL V A++V++R
Sbjct: 86 RREKKAHGTMKQLEGDYARGMK-VLLVDDVATTGGTLLDIARLLKSEGLEVVEALVVVDR 144
Query: 413 EQGGASVLEANGIAVKSLFTLTNLV 487
E+G + L + G+ ++SL TL ++
Sbjct: 145 EEGASEALRSEGLRLRSLTTLKKVL 169
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = +1
Query: 70 LRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETK 249
LR + SHP V L + + + +CG+ LP+A ++ +P+I R+E K
Sbjct: 31 LRKLPSHPQAFRRVVEALAAVARTIEFDAVCGIAVGGLPIATALAYTLGKPLIYARREKK 90
Query: 250 LYATKKLLEGVYEKNQTCL 306
+ T K LEG Y + L
Sbjct: 91 AHGTMKQLEGDYARGMKVL 109
>UniRef50_Q8YSY4 Cluster: Bifunctional enzyme pyrF/pyrE [Includes:
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP
decarboxylase) (OMPDCase) (OMPdecase); Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRT)
(OPRTase)]; n=7; Cyanobacteria|Rep: Bifunctional enzyme
pyrF/pyrE [Includes: Orotidine 5'-phosphate
decarboxylase (EC 4.1.1.23) (OMP decarboxylase)
(OMPDCase) (OMPdecase); Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRT)
(OPRTase)] - Anabaena sp. (strain PCC 7120)
Length = 477
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/81 (32%), Positives = 45/81 (55%)
Frame = +1
Query: 55 PISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMK 234
P LR I+S+P + V E ++K + + G+PY +LP A +++ + PMI
Sbjct: 314 PYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYGSLPTATGLALRLNCPMIFP 373
Query: 235 RKETKLYATKKLLEGVYEKNQ 297
RKE K + T++L+EG + +
Sbjct: 374 RKEVKAHGTRRLIEGNFRTGE 394
Score = 56.4 bits (130), Expect = 9e-07
Identities = 25/71 (35%), Positives = 46/71 (64%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNLVR 490
V+D++ SG S++E + L+ GL V V+ ++ EQG L+ANG ++ T++ +
Sbjct: 399 VDDILISGKSVMEGADKLKSAGLNVHDIVVFIDHEQGVKDKLQANGYRGHAVLTISEITS 458
Query: 491 MLHKAGRIDND 523
+LH+AGRI+++
Sbjct: 459 VLHQAGRINDE 469
>UniRef50_Q25566 Cluster: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)]; n=1; Naegleria
gruberi|Rep: Uridine 5'-monophosphate synthase (UMP
synthase) [Includes: Orotate phosphoribosyltransferase
(EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate
decarboxylase (EC 4.1.1.23) (OMPdecase)] - Naegleria
gruberi
Length = 494
Score = 57.6 bits (133), Expect = 4e-07
Identities = 24/49 (48%), Positives = 35/49 (71%)
Frame = +1
Query: 154 MICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKLLEGVYEKNQT 300
+ICGVPY+AL + +S+ D PM++ RKE K Y T ++EG+Y KN+T
Sbjct: 75 VICGVPYSALTFSSCMSMTYDLPMVICRKERKQYGTGNMVEGIYTKNET 123
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R++++ Y Y K + +EDV+TSG S++ET E L EGL+VT A++ L R
Sbjct: 102 RKERKQYGTGNMVEGIYTKNETNCILIEDVITSGASIVETAEKLENEGLLVTDALVFLTR 161
Query: 413 EQ----GGASVLEANG--IAVKSLFTLTNLVRMLHKAGRIDNDTVELIFDHI 550
EQ G +L+ V T+T + ++L G++ + E I I
Sbjct: 162 EQLPLTNGMHILKKGEKVYNVHPCLTMTEVTQVLLDEGKMSQEQREDILQFI 213
>UniRef50_Q9HM15 Cluster: Orotate phosphoribosyltransferase; n=3;
Thermoplasmatales|Rep: Orotate phosphoribosyltransferase
- Thermoplasma acidophilum
Length = 171
Score = 56.8 bits (131), Expect = 7e-07
Identities = 24/58 (41%), Positives = 41/58 (70%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNL 484
+EDVVT+G S+L+ V TLR+ G +V A V++RE+GG+ +L+ NGI + + ++ +
Sbjct: 109 IEDVVTTGNSVLKAVNTLRENGAVVKRAYCVVDREEGGSDLLKENGIDLHPIIRISQV 166
>UniRef50_Q2IFH8 Cluster: Orotate phosphoribosyltransferase
precursor; n=8; Deltaproteobacteria|Rep: Orotate
phosphoribosyltransferase precursor - Anaeromyxobacter
dehalogenans (strain 2CP-C)
Length = 189
Score = 55.6 bits (128), Expect = 2e-06
Identities = 23/58 (39%), Positives = 39/58 (67%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFT 472
R +EDVVT+GGS L+ +E R E L+ + +++R++GG +EA G+ +++LFT
Sbjct: 126 RVAVIEDVVTTGGSALKAIERCRAEHLVPVACLALVDRQEGGREAIEAQGVPLQALFT 183
>UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;
Methanopyrus kandleri|Rep: Orotate
phosphoribosyltransferase - Methanopyrus kandleri
Length = 183
Score = 55.6 bits (128), Expect = 2e-06
Identities = 24/63 (38%), Positives = 42/63 (66%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
++ + V+DV T+GGSLLE +E + +EG V AV+V++R++G L+ G+ + S+ T
Sbjct: 109 RKVVLVDDVATTGGSLLEALEAIEEEGGEVRDAVVVVDRQEGAEEALKERGVRLSSVLTA 168
Query: 476 TNL 484
+L
Sbjct: 169 DDL 171
Score = 33.1 bits (72), Expect = 9.5
Identities = 18/65 (27%), Positives = 34/65 (52%)
Frame = +1
Query: 85 SHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATK 264
+HP ++ A++ L +++ ++ G A+PL V+S+ PM + RK K Y T
Sbjct: 42 THPKVLDALTDALLEVLPD--GDVLAGPELGAVPLVSVLSVKAGLPMAIVRKRKKEYGTG 99
Query: 265 KLLEG 279
+ + G
Sbjct: 100 ERIVG 104
>UniRef50_Q8DHW5 Cluster: Orotate phosphoribosyltransferase; n=18;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 189
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/64 (37%), Positives = 44/64 (68%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNLVR 490
+EDV+T+GGS L+ V L++ G +V + +++R+ GGA+ A GI ++SLF +++L
Sbjct: 125 LEDVITTGGSALKAVGRLQEAGYVVNEVLGIVDRQGGGAAAFAAQGIPLRSLFQISDLEA 184
Query: 491 MLHK 502
L++
Sbjct: 185 YLNR 188
>UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Orotate
phosphoribosyltransferase - Hyperthermus butylicus
(strain DSM 5456 / JCM 9403)
Length = 201
Score = 54.8 bits (126), Expect = 3e-06
Identities = 27/74 (36%), Positives = 43/74 (58%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R L V+DV T+G SL VE+LR+ G A+++++REQG L G+ + SL TL
Sbjct: 112 RRVLVVDDVATTGSSLASAVESLREAGAEPVAAMVIVDREQGAVERLADYGVKLYSLATL 171
Query: 476 TNLVRMLHKAGRID 517
++ + G +D
Sbjct: 172 REIIHAMVVKGYLD 185
>UniRef50_Q0W6Q2 Cluster: Orotate phosphoribosyltransferase; n=1;
uncultured methanogenic archaeon RC-I|Rep: Orotate
phosphoribosyltransferase - Uncultured methanogenic
archaeon RC-I
Length = 175
Score = 53.6 bits (123), Expect = 6e-06
Identities = 27/67 (40%), Positives = 40/67 (59%)
Frame = +2
Query: 287 KKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSL 466
+K ++ VEDVVT+ L + TLR+ GL V V V++RE+GG LE G+ V+SL
Sbjct: 105 QKGEKVFVVEDVVTTARGALGAIHTLREAGLAVDEMVCVVDREEGGRESLEQEGVKVRSL 164
Query: 467 FTLTNLV 487
+ L+
Sbjct: 165 VKSSELL 171
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/74 (29%), Positives = 42/74 (56%)
Frame = +1
Query: 76 VIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLY 255
+ ++P + + ++ +LI + G+ ++PLA V S+ + P ++ RK TK Y
Sbjct: 36 IFETNPVCLSVIGDRIAKLIP-AGTRRLAGIEIGSIPLAAVASVKSGMPFVVVRKATKGY 94
Query: 256 ATKKLLEGVYEKNQ 297
T KL+EGV++K +
Sbjct: 95 GTNKLIEGVWQKGE 108
>UniRef50_A3DM49 Cluster: Orotate phosphoribosyltransferase; n=1;
Staphylothermus marinus F1|Rep: Orotate
phosphoribosyltransferase - Staphylothermus marinus
(strain ATCC 43588 / DSM 3639 / F1)
Length = 203
Score = 53.2 bits (122), Expect = 8e-06
Identities = 29/85 (34%), Positives = 47/85 (55%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+ L V+DV T+GGSL V +R G IV A + ++RE+G L+ G+ + SL +
Sbjct: 113 RNVLVVDDVATTGGSLEHAVNAVRSMGGIVEKAFVFVDREEGARERLKRLGVELISLMNI 172
Query: 476 TNLVRMLHKAGRIDNDTVELIFDHI 550
++ +L K ID T LI +++
Sbjct: 173 WFIINVLVKHRLIDEQTYYLIKNYL 197
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/77 (23%), Positives = 40/77 (51%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
+P LR++ S+ + + ++ ++ ++ G+ A + A I+ T +P+
Sbjct: 33 SPYYIDLRILPSYYDIYSKIIDISLSKLEKLNFDIVVGIESAGIIHASFIACKTHKPVGY 92
Query: 232 KRKETKLYATKKLLEGV 282
RK+ K + TK+L+EG+
Sbjct: 93 VRKKPKQHGTKRLVEGI 109
>UniRef50_Q9HNG2 Cluster: Orotate phosphoribosyltransferase; n=4;
Halobacteriaceae|Rep: Orotate phosphoribosyltransferase
- Halobacterium salinarium (Halobacterium halobium)
Length = 175
Score = 53.2 bits (122), Expect = 8e-06
Identities = 23/64 (35%), Positives = 42/64 (65%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+ + VED+ T+G S ++ V+ LR G V A+IV++RE+GG +L +G+ + +L T
Sbjct: 109 EEVVVVEDIATTGQSAVDAVDALRDAGATVNRALIVVDREEGGRELLAEHGVEMAALVTA 168
Query: 476 TNLV 487
++L+
Sbjct: 169 SDLL 172
>UniRef50_O67742 Cluster: Orotate phosphoribosyltransferase; n=1;
Aquifex aeolicus|Rep: Orotate phosphoribosyltransferase
- Aquifex aeolicus
Length = 183
Score = 53.2 bits (122), Expect = 8e-06
Identities = 27/64 (42%), Positives = 40/64 (62%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R +EDVVT+G S L+ V+ R+ GL V V++RE+GG +E GI + SLF L
Sbjct: 120 ERVAVLEDVVTTGSSALKAVKACREYGLEVIGVFAVVDREEGGRENIEKEGIPLYSLFKL 179
Query: 476 TNLV 487
+ L+
Sbjct: 180 SELL 183
>UniRef50_Q8F1Z0 Cluster: Orotate phosphoribosyltransferase 1; n=4;
Leptospira|Rep: Orotate phosphoribosyltransferase 1 -
Leptospira interrogans
Length = 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 20/70 (28%), Positives = 44/70 (62%)
Frame = +2
Query: 293 IKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFT 472
+K+ + ++DV+T+GGS ++ + +LR G+ V V +L+R++GG + A G+ + +F
Sbjct: 125 VKQCVVIDDVITTGGSTIQAIRSLRDCGIEVVQGVCILDRQEGGKDAILAEGVEMFPIFK 184
Query: 473 LTNLVRMLHK 502
++ + H+
Sbjct: 185 KSDFGNLEHE 194
>UniRef50_A0B8Q9 Cluster: Orotate phosphoribosyltransferase; n=1;
Methanosaeta thermophila PT|Rep: Orotate
phosphoribosyltransferase - Methanosaeta thermophila
(strain DSM 6194 / PT) (Methanothrixthermophila (strain
DSM 6194 / PT))
Length = 187
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/84 (34%), Positives = 46/84 (54%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R+K + + +R M+ + V+DVVT+G SLL ++E L + G + VL+R
Sbjct: 95 RKKAKRHGKRRFIEGPLMEAGAKVAVVDDVVTTGNSLLRSIERLEEAGYTPIQTLAVLDR 154
Query: 413 EQGGASVLEANGIAVKSLFTLTNL 484
+GG L A G ++SLFT +L
Sbjct: 155 MEGGREALSAAGFELESLFTRDDL 178
>UniRef50_Q8YM41 Cluster: Orotate phosphoribosyltransferase; n=4;
Cyanobacteria|Rep: Orotate phosphoribosyltransferase -
Anabaena sp. (strain PCC 7120)
Length = 206
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/70 (31%), Positives = 45/70 (64%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
+ + +EDVVT+G S ++ V+ LR G +V + +++R+QGGA ++ G+ +++FT+
Sbjct: 136 KVVVLEDVVTTGQSAMKAVDRLRAAGYVVDEVISLVDRQQGGAEFYQSVGLKFEAVFTIM 195
Query: 479 NLVRMLHKAG 508
+L + + G
Sbjct: 196 DLQQRYQELG 205
>UniRef50_Q74CN6 Cluster: Orotate phosphoribosyltransferase; n=8;
Deltaproteobacteria|Rep: Orotate
phosphoribosyltransferase - Geobacter sulfurreducens
Length = 182
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/63 (38%), Positives = 42/63 (66%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
+ + VEDVVT+GGS ++ V+ +EGL V V +++RE+GG +E G ++++FT +
Sbjct: 119 KVVIVEDVVTTGGSSMKAVKRAEEEGLKVLCIVSLVDREEGGRENIEQEGYELRTIFTKS 178
Query: 479 NLV 487
L+
Sbjct: 179 ELL 181
>UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;
Methanomicrobiales|Rep: Orotate
phosphoribosyltransferase - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 172
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/64 (39%), Positives = 37/64 (57%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
KR L VEDV TSGGS + +E LR G +VT + V++R +G L+ I + L +
Sbjct: 107 KRILLVEDVTTSGGSAVFGIEQLRSAGAVVTDVIAVVDRNEGAGKTLQGLDITLTPLVRM 166
Query: 476 TNLV 487
+L+
Sbjct: 167 QDLI 170
Score = 35.9 bits (79), Expect = 1.3
Identities = 18/77 (23%), Positives = 39/77 (50%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMI 228
++ + ++ ++ P ++ ++ E L + GV +PLAV +S+ +D+P +
Sbjct: 28 KSTVYIDIKKAITSPAILKKIA--AEVLTHSTDFDAVAGVAVGGVPLAVSVSLASDKPYV 85
Query: 229 MKRKETKLYATKKLLEG 279
+ RKE K + L+ G
Sbjct: 86 IIRKEQKGHGLASLIIG 102
>UniRef50_Q1MPM5 Cluster: Orotate phosphoribosyltransferase; n=2;
Desulfovibrionaceae|Rep: Orotate
phosphoribosyltransferase - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 187
Score = 52.0 bits (119), Expect = 2e-05
Identities = 25/63 (39%), Positives = 36/63 (57%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R +EDVVT+G SLL E ++ GL + + +RE+GG L+ G ++SLFT
Sbjct: 119 RVAVIEDVVTTGNSLLLACERIKASGLTIAILCTIFDREEGGKEFLQEAGYELRSLFTRK 178
Query: 479 NLV 487
LV
Sbjct: 179 ELV 181
Score = 34.7 bits (76), Expect = 3.1
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +1
Query: 64 FXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLA---VVISINTDRPM--I 228
F R HP + + L L+ V + G+ A PL VIS DRP+ +
Sbjct: 34 FDCRQTALHPEGAWLIGNLLNALLVDVDISAVGGMTLGADPLISAITVISYELDRPLSGL 93
Query: 229 MKRKETKLYATKKLLEGV 282
+ RKE KL+ T + +EG+
Sbjct: 94 IVRKEAKLHGTAQYVEGL 111
>UniRef50_A7HGM2 Cluster: Orotate phosphoribosyltransferase; n=1;
Anaeromyxobacter sp. Fw109-5|Rep: Orotate
phosphoribosyltransferase - Anaeromyxobacter sp. Fw109-5
Length = 212
Score = 52.0 bits (119), Expect = 2e-05
Identities = 23/58 (39%), Positives = 38/58 (65%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFT 472
R + +EDVVT+GGS L+ +E R E L + +++R +GG +EA G+ +++LFT
Sbjct: 149 RVVVIEDVVTTGGSALKAIERCRVEKLEPVACLALVDRMEGGREAIEAQGVPLQALFT 206
>UniRef50_Q7UYX5 Cluster: Orotate phosphoribosyltransferase; n=3;
Planctomycetaceae|Rep: Orotate phosphoribosyltransferase
- Rhodopirellula baltica
Length = 193
Score = 51.6 bits (118), Expect = 3e-05
Identities = 23/60 (38%), Positives = 39/60 (65%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
++ + VEDV+TSGGS L+ VE ++ GL V + + +++R GGA G+ +K+L T+
Sbjct: 127 QKVVIVEDVITSGGSALKAVEAVQAFGLEVQYVLAIIDRLAGGAEAFAQKGLELKTLTTI 186
>UniRef50_Q6AJ35 Cluster: Probable orotate
phosphoribosyltransferase; n=1; Desulfotalea
psychrophila|Rep: Probable orotate
phosphoribosyltransferase - Desulfotalea psychrophila
Length = 184
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/59 (38%), Positives = 38/59 (64%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLTNLV 487
+EDVVT+GG+L++ ++ + G V V+ER++GG +VL G +KS+FT L+
Sbjct: 124 LEDVVTTGGTLIKVIDRVEAAGFKVGLVATVIERQEGGTAVLAEAGYTLKSIFTREELL 182
>UniRef50_Q2LWJ4 Cluster: Orotate phosphoribosyltransferase; n=2;
Syntrophobacterales|Rep: Orotate
phosphoribosyltransferase - Syntrophus aciditrophicus
(strain SB)
Length = 196
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/72 (30%), Positives = 47/72 (65%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R + ++DV+T+GGS + +E R+ GL++ + +++RE+GG + +EA+ V ++ T
Sbjct: 122 ERVVILDDVITTGGSTITAIERAREAGLVIDRVIALIDREEGGRANIEAHVPRVDAVLTR 181
Query: 476 TNLVRMLHKAGR 511
+ + M H +G+
Sbjct: 182 SEI--MNHFSGK 191
>UniRef50_A3H774 Cluster: Orotate phosphoribosyltransferase; n=1;
Caldivirga maquilingensis IC-167|Rep: Orotate
phosphoribosyltransferase - Caldivirga maquilingensis
IC-167
Length = 181
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/68 (32%), Positives = 41/68 (60%)
Frame = +2
Query: 281 YMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVK 460
Y K + L ++DVVT+GG++L+++ L + GL V ++++R +GG + +G
Sbjct: 103 YYKGGEGVLLIDDVVTTGGTILDSIRVLEENGLRVIEVAVIVDRLEGGLDAIRRSGYRAW 162
Query: 461 SLFTLTNL 484
SL T+ +L
Sbjct: 163 SLLTVKDL 170
>UniRef50_A7D434 Cluster: Orotate phosphoribosyltransferase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Orotate
phosphoribosyltransferase - Halorubrum lacusprofundi
ATCC 49239
Length = 191
Score = 50.4 bits (115), Expect = 6e-05
Identities = 22/64 (34%), Positives = 40/64 (62%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+ + +ED+ T+G S ++ VE LR+ G V ++V++RE+G +L + I ++SL T
Sbjct: 122 EEVVVLEDIATTGQSAVDAVEALREAGATVNRVLVVVDREEGAEELLADHDIELESLLTA 181
Query: 476 TNLV 487
T L+
Sbjct: 182 TELL 185
Score = 35.1 bits (77), Expect = 2.3
Identities = 15/47 (31%), Positives = 25/47 (53%)
Frame = +1
Query: 157 ICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKLLEGVYEKNQ 297
+ GV A+PL V + RP ++ RK+ K Y T +EG ++ +
Sbjct: 76 LAGVALGAVPLVAVTATELGRPYVIARKQAKEYGTGNRIEGRLDEGE 122
>UniRef50_O27888 Cluster: Orotate phosphoribosyltransferase; n=2;
Euryarchaeota|Rep: Orotate phosphoribosyltransferase -
Methanobacterium thermoautotrophicum
Length = 180
Score = 50.4 bits (115), Expect = 6e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Frame = +2
Query: 284 MKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKS 463
++K R VEDV T+GGSLL+ V +++ G IV A ++++RE+G + GI +
Sbjct: 111 LQKGDRVAVVEDVTTTGGSLLKAVRAIQENGGIVEKAFVIVDREEGAVDEFKREGITLIP 170
Query: 464 LFTLTN 481
L ++++
Sbjct: 171 LLSVSD 176
Score = 43.2 bits (97), Expect = 0.009
Identities = 19/45 (42%), Positives = 29/45 (64%)
Frame = +1
Query: 157 ICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKLLEGVYEK 291
I G A+P+A +S+ + +P++M RKE K Y T KL+EG +K
Sbjct: 69 IAGPALGAVPIATAVSLYSRKPLLMIRKEKKGYGTSKLIEGDLQK 113
>UniRef50_Q89BL4 Cluster: Orotate phosphoribosyltransferase; n=11;
Bradyrhizobiaceae|Rep: Orotate phosphoribosyltransferase
- Bradyrhizobium japonicum
Length = 187
Score = 50.4 bits (115), Expect = 6e-05
Identities = 22/65 (33%), Positives = 40/65 (61%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
KR + VEDV T+GGS ++ VE++R+ G V + +++RE+G A G+ +SL+
Sbjct: 122 KRVVIVEDVTTTGGSAMKAVESVRETGAEVVLVLTMVDREEGATDTFGAAGLPFRSLYKA 181
Query: 476 TNLVR 490
+ ++
Sbjct: 182 SEFLK 186
>UniRef50_UPI00015BB0AE Cluster: orotate phosphoribosyltransferase;
n=1; Ignicoccus hospitalis KIN4/I|Rep: orotate
phosphoribosyltransferase - Ignicoccus hospitalis KIN4/I
Length = 188
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
++ + V+DV T+GGSL +T++ LR G A +L+RE+G +E G+ L TL
Sbjct: 119 QKVVVVDDVTTTGGSLAKTIDALRDFGAEPVLAAALLDREEGSVEEIEKRGVEFIRLLTL 178
Query: 476 TNLVRML 496
++R L
Sbjct: 179 NQVLRGL 185
Score = 35.1 bits (77), Expect = 2.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQLIKX-VHHXMICGVPYAALPLAVVISINTDRPM 225
R+ + +R + S P L + + LI+ V + I GV +PLA +S+ PM
Sbjct: 37 RSDVYVDMRKLWSFPKLARLAALLMSALIRSKVEYATIVGVATGGIPLAAHLSVTLGWPM 96
Query: 226 IMKRKETKLYATKKLLEGV 282
R + K + +L+EGV
Sbjct: 97 GYARPKRKEHGQMRLVEGV 115
>UniRef50_A7DRA9 Cluster: Orotate phosphoribosyltransferase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Orotate
phosphoribosyltransferase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 201
Score = 48.4 bits (110), Expect = 2e-04
Identities = 18/84 (21%), Positives = 47/84 (55%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
+ + ++DV T+GGS++ +++L++ + V A +++ R +G L + + S+ +
Sbjct: 116 QVVMIDDVATTGGSVVNAIKSLKEVNISVKDAYVIVNRMEGADEALNELDVKMHSILNIL 175
Query: 479 NLVRMLHKAGRIDNDTVELIFDHI 550
+ LH+ +D++ +E + + I
Sbjct: 176 QITEALHEQNLVDDEILEKVKNQI 199
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Frame = +1
Query: 70 LRVIVSHPX----LMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKR 237
LR++ S+P ++ + +++ Q I I VP L +A ++I T +P+I R
Sbjct: 36 LRLVPSYPQEFRKMVKYLENEIAQNIGLDKFDSIVSVPTGGLVIASALAIETVKPLIYVR 95
Query: 238 KETKLYATKKLLEG 279
+ K Y T K +EG
Sbjct: 96 SKPKDYGTSKSVEG 109
>UniRef50_A3EQ68 Cluster: Orotate phosphoribosyltransferase; n=1;
Leptospirillum sp. Group II UBA|Rep: Orotate
phosphoribosyltransferase - Leptospirillum sp. Group II
UBA
Length = 212
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/63 (34%), Positives = 39/63 (61%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R + VEDVVT+G S ++ V+ + G V + +++RE+GG ++ E G+ +SLF+L
Sbjct: 140 RVVVVEDVVTTGASGMKAVKACQDAGHRVLKVISLVDREEGGRALFEGAGLPFESLFSLK 199
Query: 479 NLV 487
+
Sbjct: 200 KFI 202
>UniRef50_Q55574 Cluster: Orotate phosphoribosyltransferase; n=9;
Cyanobacteria|Rep: Orotate phosphoribosyltransferase -
Synechocystis sp. (strain PCC 6803)
Length = 198
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/62 (33%), Positives = 39/62 (62%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
+ + +EDVVT+G S + VE LR G V + +++R+QGG ++ G+ ++LFT+
Sbjct: 130 KVVVLEDVVTTGKSAMLAVERLRNAGYQVDTVISLVDRQQGGREFYQSQGLTFQALFTIG 189
Query: 479 NL 484
++
Sbjct: 190 DI 191
>UniRef50_Q1PWC9 Cluster: Similar to orotate phosphoribosyl
transferase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to orotate phosphoribosyl
transferase - Candidatus Kuenenia stuttgartiensis
Length = 231
Score = 47.6 bits (108), Expect = 4e-04
Identities = 19/63 (30%), Positives = 39/63 (61%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
+ + V+DVVT+GGS ++ ++ R+ L + + +++R++GG +E + +SLFT
Sbjct: 162 KVVIVDDVVTTGGSTIQAIDRAREHKLEIVKVIALVDRQEGGRENIEKKMVIFESLFTRD 221
Query: 479 NLV 487
L+
Sbjct: 222 ELI 224
>UniRef50_Q9Y9D8 Cluster: Orotate phosphoribosyltransferase; n=1;
Aeropyrum pernix|Rep: Orotate phosphoribosyltransferase
- Aeropyrum pernix
Length = 186
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R + V+DV T+G S+ +++E LR G V A+++++R +G +L G+ + S+ TL
Sbjct: 116 RVVVVDDVATTGTSIAKSIEVLRSNGYTVGTALVLVDRGEGAGELLARMGVRLVSVATLK 175
Query: 479 NLVRMLHKAG 508
++ L G
Sbjct: 176 TILEKLGWGG 185
>UniRef50_Q98AN7 Cluster: Orotate phosphoribosyltransferase 1; n=1;
Mesorhizobium loti|Rep: Orotate
phosphoribosyltransferase 1 - Rhizobium loti
(Mesorhizobium loti)
Length = 198
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/64 (34%), Positives = 40/64 (62%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
K L V+DV TSG S+L+ +E +R+ G IV A +++R++G ++L +G+ + S+
Sbjct: 132 KVVLIVDDVATSGKSILKAIEEVRRVGGIVGDAACLVDRDEGATALLAQHGVTLHSVLHA 191
Query: 476 TNLV 487
+ V
Sbjct: 192 SEFV 195
>UniRef50_Q58MW1 Cluster: Cyanobacterial orotate
phosphoribosyltransferase; n=1; Cyanophage P-SSM2|Rep:
Cyanobacterial orotate phosphoribosyltransferase -
Cyanophage P-SSM2
Length = 214
Score = 46.8 bits (106), Expect = 7e-04
Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 5/102 (4%)
Frame = +2
Query: 197 SSPSTRTDQ*S*REKKQNYMPQRNYWRAYMKKIKRALXV--EDVVTSGGSLLETVETLRK 370
S + R D R+K++ Y N W +K A V EDV T+GGS L VE LR
Sbjct: 94 SGGNIRVDALIVRKKQKGY--GANAWIEGKLPMKGAKVVVLEDVTTTGGSALIAVEKLRD 151
Query: 371 EGLIVTHAVIVLEREQGG---ASVLEANGIAVKSLFTLTNLV 487
G +V + V++R+ G A + EAN I + SLFTL ++
Sbjct: 152 AGYVVEKIITVVDRQVDGEADAKMKEAN-IELISLFTLQEII 192
>UniRef50_Q8NM11 Cluster: Orotate phosphoribosyltransferase; n=28;
Actinomycetales|Rep: Orotate phosphoribosyltransferase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 184
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
K+ L VED T+G S L V LR+ G+ V V++R G V+ A G+ +SL L
Sbjct: 119 KKVLVVEDTTTTGNSPLTAVAALREAGIEVVGVATVVDRATGADEVIAAEGLPYRSLLGL 178
Query: 476 TNL 484
++L
Sbjct: 179 SDL 181
>UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;
Thermococcaceae|Rep: Orotate phosphoribosyltransferase -
Pyrococcus horikoshii
Length = 186
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/80 (35%), Positives = 41/80 (51%)
Frame = +2
Query: 284 MKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKS 463
++K + L VEDV T+GGS++ + LR+ G V +V++RE+G +E G
Sbjct: 109 VQKGDKVLLVEDVTTTGGSVIRAAKILREHGADVVGIFVVVDREEGAKENIEKEGFKFYP 168
Query: 464 LFTLTNLVRMLHKAGRIDND 523
L LV L KA I D
Sbjct: 169 LV----LVSELFKAAGISKD 184
Score = 42.3 bits (95), Expect = 0.015
Identities = 18/81 (22%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 70 LRVIVSHPXLMVAVSHQLEQLIKXVH--HXMICGVPYAALPLAVVISINTDRPMIMKRKE 243
++ ++++P + ++ +++ + ++ + I G A+P+A +S+ T++P+++ RK+
Sbjct: 36 IKSLITNPKALRIIAKLIKEKAEELNLNYDKIAGPELGAVPIATALSLETNKPLLIVRKK 95
Query: 244 TKLYATKKLLEGVYEKNQTCL 306
K + T K++EG +K L
Sbjct: 96 KKEHGTGKVIEGNVQKGDKVL 116
>UniRef50_P58859 Cluster: Orotate phosphoribosyltransferase; n=6;
Euryarchaeota|Rep: Orotate phosphoribosyltransferase -
Methanosarcina acetivorans
Length = 187
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/64 (31%), Positives = 39/64 (60%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R + +EDV TSGGS+ + ++ +R+ G V + + V++RE+G L+ + L T +
Sbjct: 124 RLVMLEDVTTSGGSVRDAIKVVRETGACVKYVITVVDREEGAKEKLKEADAELVPLVTAS 183
Query: 479 NLVR 490
+L++
Sbjct: 184 DLLK 187
Score = 39.1 bits (87), Expect = 0.14
Identities = 18/63 (28%), Positives = 30/63 (47%)
Frame = +1
Query: 91 PXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKL 270
P + ++ Q +K + + GV +PLA +S+ T P+++ RK K Y TK
Sbjct: 55 PKTLKIIARQAALRVKEMGVGTVAGVELGGVPLATAVSLETGLPLLIVRKSVKEYGTKSR 114
Query: 271 LEG 279
G
Sbjct: 115 FVG 117
>UniRef50_Q7VDR1 Cluster: Orotate phosphoribosyltransferase; n=7;
Prochlorococcus marinus|Rep: Orotate
phosphoribosyltransferase - Prochlorococcus marinus
Length = 192
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/55 (38%), Positives = 35/55 (63%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+EDVVT+G S L+ V L+ G V + +++R++GGA ++ G+ + SLF L
Sbjct: 128 LEDVVTTGRSSLKAVNQLQNAGYRVNRIISIVDRQEGGAFEIKKAGLDLVSLFVL 182
>UniRef50_Q8ZTG3 Cluster: Orotate phosphoribosyltransferase; n=5;
Pyrobaculum|Rep: Orotate phosphoribosyltransferase -
Pyrobaculum aerophilum
Length = 193
Score = 44.4 bits (100), Expect = 0.004
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEAN-GIAVKSLFT 472
KRA V+DV+T+G S+L + +R G V V+ L+R Q GA ++ G+ V S++
Sbjct: 105 KRAAVVDDVLTTGKSVLNAIRAVRASGGEVAGVVVFLDRGQCGAEAVKREAGVYVYSVYK 164
Query: 473 LTNLVRMLHKAGRIDNDTVELIFDHIKE 556
+ L+ L I + + D++ +
Sbjct: 165 MRELLEELRP--HIGEERYRSVLDYLSQ 190
Score = 40.7 bits (91), Expect = 0.047
Identities = 22/76 (28%), Positives = 35/76 (46%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIM 231
+P LR ++ P L V + E ++ + +I GV +P A V+ +PM
Sbjct: 24 SPFYVDLRSVLGEPELFQWVIERYEAVLSGLEFDVIIGVATGGIPYASVLGYRLKKPMGY 83
Query: 232 KRKETKLYATKKLLEG 279
R E K Y T + +EG
Sbjct: 84 VRDEAKGYGTGRQIEG 99
>UniRef50_A7M6E4 Cluster: Orotate phosphoribosyltransferase; n=1;
Phanerochaete sordida|Rep: Orotate
phosphoribosyltransferase - Phanerochaete sordida
Length = 231
Score = 43.2 bits (97), Expect = 0.009
Identities = 20/45 (44%), Positives = 33/45 (73%)
Frame = +2
Query: 290 KIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGG 424
K KR L ++DV T+G ++ + ++T+RKEG V AV++L+RE+ G
Sbjct: 130 KGKRVLVLDDVATAGTAIRQAMDTVRKEGGEVVGAVLMLDREEVG 174
>UniRef50_Q6ACA3 Cluster: Orotate phosphoribosyltransferase; n=1;
Leifsonia xyli subsp. xyli|Rep: Orotate
phosphoribosyltransferase - Leifsonia xyli subsp. xyli
Length = 182
Score = 41.9 bits (94), Expect = 0.020
Identities = 18/51 (35%), Positives = 30/51 (58%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANG 448
KR + +ED T+GGS L +E L++ G + +V++R+ G +EA G
Sbjct: 117 KRVIVLEDTSTTGGSPLTAIEALKRAGAEIAAVGVVVDRDTGAREAIEAAG 167
>UniRef50_Q59049 Cluster: Adenine phosphoribosyltransferase; n=10;
Euryarchaeota|Rep: Adenine phosphoribosyltransferase -
Methanococcus jannaschii
Length = 183
Score = 41.9 bits (94), Expect = 0.020
Identities = 16/61 (26%), Positives = 38/61 (62%)
Frame = +2
Query: 284 MKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKS 463
++K + + ++DV+++GG+++ ++ L++ G + + V+ER +G V E G +K+
Sbjct: 110 IEKGDKVVIIDDVISTGGTMIAIIDALKRAGAEIKDIICVIERGEGKKIVEEKTGYKIKT 169
Query: 464 L 466
L
Sbjct: 170 L 170
>UniRef50_UPI00015BCA71 Cluster: UPI00015BCA71 related cluster; n=1;
unknown|Rep: UPI00015BCA71 UniRef100 entry - unknown
Length = 184
Score = 41.5 bits (93), Expect = 0.027
Identities = 20/68 (29%), Positives = 34/68 (50%)
Frame = +2
Query: 284 MKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKS 463
++ +K +EDV T+GGS L+ + L V +++RE+G +E G S
Sbjct: 117 LENVKNVAILEDVSTTGGSSLKAANVCKNASLNVVGIFTIVDREEGAKENIEKEGFKFYS 176
Query: 464 LFTLTNLV 487
+F L L+
Sbjct: 177 VFKLFELL 184
>UniRef50_Q01WL5 Cluster: Orotate phosphoribosyltransferase; n=3;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Solibacter usitatus (strain Ellin6076)
Length = 197
Score = 41.1 bits (92), Expect = 0.036
Identities = 20/44 (45%), Positives = 28/44 (63%)
Frame = +2
Query: 302 ALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASV 433
A+ VEDV+T+GGS ++ VE LR G V A +++R G A V
Sbjct: 117 AVVVEDVITTGGSTIDVVEALRSAGARVLAAGSIIDRSGGQADV 160
>UniRef50_Q82EU1 Cluster: Orotate phosphoribosyltransferase; n=7;
Actinobacteria (class)|Rep: Orotate
phosphoribosyltransferase - Streptomyces avermitilis
Length = 182
Score = 41.1 bits (92), Expect = 0.036
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +2
Query: 290 KIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEA 442
K +R L VED T+GGS L VE +R+ G V +++R G A +EA
Sbjct: 114 KGRRVLVVEDTSTTGGSPLTAVEAVREAGAEVVGVATIVDRATGAAEKIEA 164
>UniRef50_Q7NDF9 Cluster: Gll4276 protein; n=1; Gloeobacter
violaceus|Rep: Gll4276 protein - Gloeobacter violaceus
Length = 208
Score = 40.7 bits (91), Expect = 0.047
Identities = 18/55 (32%), Positives = 33/55 (60%)
Frame = +2
Query: 311 VEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
V+DVVT+G S L+ E + GL V + +++R QGG ++ G ++L+++
Sbjct: 148 VDDVVTTGASGLQAAEKAEEAGLKVVKILALVDRHQGGGALYAGRGYPFEALYSI 202
>UniRef50_O26962 Cluster: PyrE-like protein; n=3;
Methanobacteriaceae|Rep: PyrE-like protein -
Methanobacterium thermoautotrophicum
Length = 202
Score = 40.7 bits (91), Expect = 0.047
Identities = 20/65 (30%), Positives = 39/65 (60%)
Frame = +2
Query: 290 KIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLF 469
K KR + V+DV+TSG ++ E VE L+ +G ++++++ + E +G+ V+SL
Sbjct: 141 KGKRVVVVDDVITSGRTIAEVVEVLKNQGAKPIAVTVLIDKK----GISEVDGVPVESLI 196
Query: 470 TLTNL 484
++ L
Sbjct: 197 RVSRL 201
>UniRef50_Q0W496 Cluster: Adenine phosphoribosyltransferase; n=7;
Euryarchaeota|Rep: Adenine phosphoribosyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 191
Score = 40.3 bits (90), Expect = 0.062
Identities = 22/75 (29%), Positives = 41/75 (54%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R L V+DV+++GG+L ++ L G + V+V++R G ++E G V++L T+
Sbjct: 116 RVLIVDDVISTGGTLAAVIKALEMAGAEIKDIVVVIQR-GNGKKIIEDMGYNVQTLVTID 174
Query: 479 NLVRMLHKAGRIDND 523
+ G ID++
Sbjct: 175 VDENGVQVLGCIDDE 189
>UniRef50_Q45918 Cluster: Orotate phosphoribosyltransferase; n=2;
Coxiella burnetii|Rep: Orotate phosphoribosyltransferase
- Coxiella burnetii
Length = 209
Score = 40.3 bits (90), Expect = 0.062
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVH--HXMICGVPYAALPLAVVISINTDRPM 225
+PI R+I+S+P + QLI+ H ++ G A +P A I+ D PM
Sbjct: 33 SPIYCDNRLIISYPEKRKMIIEAFLQLIEKNHLSFDIVAGTATAGIPHAAWIADRLDLPM 92
Query: 226 IMKRKETKLYATKKLLEGVYEKNQTCL 306
I R + K + + +EG K Q L
Sbjct: 93 IYVRAKAKTHGKQNQIEGRIRKGQRAL 119
Score = 37.1 bits (82), Expect = 0.58
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
Frame = +2
Query: 260 QRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLERE--QGGASV 433
++N ++K +RAL VED++++G S L LR++G+ VT + + + Q +
Sbjct: 104 KQNQIEGRIRKGQRALIVEDLISTGKSALAAGLALREKGVTVTDCIAIFSYQLPQAQQNF 163
Query: 434 LEANGIAVKSLFTLTNLVRMLHKAGRID 517
+AN I +L L+ M G ID
Sbjct: 164 SDAN-INCHALSHFDTLIEMAVDEGYID 190
>UniRef50_Q6MP84 Cluster: PyrE protein; n=6; Bacteria|Rep: PyrE
protein - Bdellovibrio bacteriovorus
Length = 179
Score = 39.9 bits (89), Expect = 0.083
Identities = 21/71 (29%), Positives = 36/71 (50%)
Frame = +1
Query: 85 SHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATK 264
+ P L+ ++ Q+ LI ++ G+ +P+A +S+ T P + RKE K Y T
Sbjct: 47 AQPTLLREIAKQMVPLIP-AGTEVLAGLEMGGIPIATALSLETGIPCVFVRKEAKEYGTC 105
Query: 265 KLLEGVYEKNQ 297
K EG+ K +
Sbjct: 106 KFAEGLEIKGK 116
>UniRef50_Q6A910 Cluster: Orotate phosphoribosyltransferase; n=126;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Propionibacterium acnes
Length = 216
Score = 39.5 bits (88), Expect = 0.11
Identities = 19/76 (25%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLERE-QGGASVLEANGIAVKSLFTL 475
+ + VED++++GGS+L+ + + +EG V + + E + G E G+ + +L
Sbjct: 122 KVIMVEDLISTGGSVLKAAQAVEREGSTVVGVLALFSYELEKGHRAFEKAGVPLYTLSNY 181
Query: 476 TNLVRMLHKAGRIDND 523
L+ + ++GRI ++
Sbjct: 182 PILIEVAAESGRITSE 197
>UniRef50_Q6G463 Cluster: Orotate phosphoribosyltransferase; n=7;
Alphaproteobacteria|Rep: Orotate
phosphoribosyltransferase - Bartonella henselae
(Rochalimaea henselae)
Length = 192
Score = 39.1 bits (87), Expect = 0.14
Identities = 22/53 (41%), Positives = 30/53 (56%)
Frame = +2
Query: 275 RAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASV 433
R +KK R + VED+VT+G S+ ETVE L G V + +L+R G V
Sbjct: 103 RFEIKKGARVVIVEDIVTTGLSIRETVEALVTAGANVLASACILDRSGGKVDV 155
>UniRef50_Q92SC6 Cluster: Orotate phosphoribosyltransferase; n=65;
Proteobacteria|Rep: Orotate phosphoribosyltransferase -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 232
Score = 39.1 bits (87), Expect = 0.14
Identities = 19/85 (22%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 281 YMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLERE--QGGASVLEANGIA 454
YM + R L +ED+ T+GGS+ + ++ +R G +V H + + + +++ G+
Sbjct: 122 YMPEGARVLVIEDLTTAGGSMFKFIDAIRAAGGVVEHGIALFYYDIFPEARGNMKSKGVD 181
Query: 455 VKSLFTLTNLVRMLHKAGRIDNDTV 529
+ + T N++ + + D T+
Sbjct: 182 LHYIATWRNVLAVARELALFDEKTL 206
>UniRef50_A1SPW6 Cluster: Orotate phosphoribosyltransferase; n=3;
Actinomycetales|Rep: Orotate phosphoribosyltransferase -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 179
Score = 38.7 bits (86), Expect = 0.19
Identities = 19/63 (30%), Positives = 31/63 (49%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R +EDV+T+GG++ + LR G V V ++R G L G+ V+ + T
Sbjct: 109 RRVTLIEDVITTGGAVRDATRALRAAGAEVDVVVCAIDRSPAGEHPLADVGLEVRPVLTK 168
Query: 476 TNL 484
L
Sbjct: 169 AEL 171
Score = 37.5 bits (83), Expect = 0.44
Identities = 20/63 (31%), Positives = 35/63 (55%)
Frame = +1
Query: 91 PXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKL 270
P L++ V+ ++ L+ ++ G+ +P+A ++S T RP + RK+ K Y T KL
Sbjct: 42 PQLLLRVAREMVGLLPD-GTDLLGGLELGGVPIATMVSSLTGRPALYVRKKAKEYGTCKL 100
Query: 271 LEG 279
EG
Sbjct: 101 AEG 103
>UniRef50_Q74J27 Cluster: Orotate phosphoribosyltransferase; n=6;
Lactobacillus|Rep: Orotate phosphoribosyltransferase -
Lactobacillus johnsonii
Length = 212
Score = 38.7 bits (86), Expect = 0.19
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLI--KXVHHXMICGVPYAALPLAVVISINTDRPM 225
+PI LR+ VS+P L ++ L LI + +I GV A +P A +++ PM
Sbjct: 32 SPIYTDLRLTVSYPDLRDMIASDLSNLIAAEFPQATIIGGVATAGIPHAALVAEKLHLPM 91
Query: 226 IMKRKETKLYATKKLLEGVYEKN 294
I R + K + + +EG + +N
Sbjct: 92 IYVRPKPKDHGKGRQIEGRFSEN 114
>UniRef50_Q8KG85 Cluster: Orotate phosphoribosyltransferase; n=14;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Chlorobium tepidum
Length = 185
Score = 37.9 bits (84), Expect = 0.33
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQG 421
++ L VEDV+T+GGS+ E +E ++ G V V++R G
Sbjct: 100 EQVLVVEDVITTGGSVAEVIELVKAAGATVAGVASVVDRSNG 141
>UniRef50_A6C842 Cluster: Orotate phosphoribosyltransferase; n=1;
Planctomyces maris DSM 8797|Rep: Orotate
phosphoribosyltransferase - Planctomyces maris DSM 8797
Length = 186
Score = 37.9 bits (84), Expect = 0.33
Identities = 21/71 (29%), Positives = 39/71 (54%)
Frame = +2
Query: 269 YWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANG 448
Y +K + + V+DV+T+ GS L +V+ + G V A+ V++R QGGA+
Sbjct: 106 YVEGPVKPGDKVVIVDDVITTAGSALLSVDRAEEFGCQVIKALGVVDRLQGGAANFAKRN 165
Query: 449 IAVKSLFTLTN 481
I ++L ++ +
Sbjct: 166 IPFEALLSIVD 176
>UniRef50_A3WSJ9 Cluster: Orotate phosphoribosyltransferase; n=1;
Nitrobacter sp. Nb-311A|Rep: Orotate
phosphoribosyltransferase - Nitrobacter sp. Nb-311A
Length = 203
Score = 37.5 bits (83), Expect = 0.44
Identities = 18/59 (30%), Positives = 31/59 (52%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFT 472
K+ + +EDV TSG S + V + G +V + +++R +G + + I SLFT
Sbjct: 138 KKVVILEDVTTSGESAMIAVAAAQAAGALVVMVLSIVDRGEGAVAFYKEKNIEFDSLFT 196
>UniRef50_O28533 Cluster: Orotate phosphoribosyltransferase; n=1;
Archaeoglobus fulgidus|Rep: Orotate
phosphoribosyltransferase - Archaeoglobus fulgidus
Length = 178
Score = 37.5 bits (83), Expect = 0.44
Identities = 17/72 (23%), Positives = 37/72 (51%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMI 228
R+ + +++ + P ++ +S + +K + I V +P+AV +S+ +P++
Sbjct: 30 RSRVYVDVKLASTFPDILEMISEGMAAKLKDLEFDRIACVELGGVPIAVALSLKMKKPLV 89
Query: 229 MKRKETKLYATK 264
+ RKE K Y K
Sbjct: 90 IFRKEKKDYGIK 101
Score = 36.3 bits (80), Expect = 1.0
Identities = 15/51 (29%), Positives = 30/51 (58%)
Frame = +2
Query: 284 MKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVL 436
+K+ ++ + VEDV+T+G S L + + G V + V++RE+ G + +
Sbjct: 108 VKEGEKVVVVEDVITTGSSALSAARRVEESGASVAAIIAVVDREESGRNFM 158
>UniRef50_A6G356 Cluster: Orotate phosphoribosyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Orotate
phosphoribosyltransferase - Plesiocystis pacifica SIR-1
Length = 224
Score = 37.1 bits (82), Expect = 0.58
Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 9/76 (11%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEG--LIVTHAVIVLEREQGGAS-------VLEANGI 451
+ + V+DV+TSG S+ E VE LR+ + VT A++ ++R + G S + E G+
Sbjct: 120 KVVLVDDVITSGRSIREAVELLREAAPDVQVTAAIVAVDRCERGRSEKTTMSELREELGV 179
Query: 452 AVKSLFTLTNLVRMLH 499
V+++ + +V LH
Sbjct: 180 DVRAIVDIREVVAYLH 195
>UniRef50_Q6LX60 Cluster: Orotate phosphoribosyltransferase; n=7;
Euryarchaeota|Rep: Orotate phosphoribosyltransferase -
Methanococcus maripaludis
Length = 185
Score = 37.1 bits (82), Expect = 0.58
Identities = 21/84 (25%), Positives = 41/84 (48%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R+K + Y +N + + +EDV T+GGS+ + V+ +R V ++++R
Sbjct: 99 RKKAKEY-GTKNKIEGELNPGDNVIVMEDVTTTGGSVSKAVDEIRAVSGNVKKIYVIVDR 157
Query: 413 EQGGASVLEANGIAVKSLFTLTNL 484
++G L N + + L T+ L
Sbjct: 158 QEGAKENLAQNNVELIPLVTIEEL 181
Score = 35.9 bits (79), Expect = 1.3
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +1
Query: 157 ICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKLLEG 279
I GV ++ +A +S+ T++ +++ RK+ K Y TK +EG
Sbjct: 73 IAGVELGSVSIATAVSLETEKDLLIIRKKAKEYGTKNKIEG 113
>UniRef50_Q1DNB0 Cluster: Orotate phosphoribosyltransferase; n=17;
Pezizomycotina|Rep: Orotate phosphoribosyltransferase -
Coccidioides immitis
Length = 238
Score = 37.1 bits (82), Expect = 0.58
Identities = 16/43 (37%), Positives = 29/43 (67%)
Frame = +2
Query: 290 KIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQ 418
K K+ + ++DV+T+G +L E V + KEG V +++L+RE+
Sbjct: 136 KGKKIVIIDDVITAGTALREAVGIIEKEGGTVVGVLVLLDREE 178
>UniRef50_Q97N11 Cluster: Orotate phosphoribosyltransferase; n=6;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Clostridium acetobutylicum
Length = 224
Score = 37.1 bits (82), Expect = 0.58
Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 13/112 (11%)
Frame = +2
Query: 278 AYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIV----LEREQGGASVL--- 436
A +++ R + VEDV T+G S+ ET+ L+ + + +I+ +ER +G S L
Sbjct: 115 AKLEEGDRVIIVEDVTTAGTSVYETMPILKSQAEVDVKGIIISVDRMERGKGDKSALTEL 174
Query: 437 -EANGIAVKSLFTLTNLVRMLHKA---GR--IDNDTVELIFDHIKECQFGTK 574
E G S+ T+ +V L+K G+ ID+ + I ++ KE +G K
Sbjct: 175 KEKFGFKTCSIVTMEEVVEYLYKKNINGKVIIDDKMKDRINEYYKE--YGVK 224
>UniRef50_A3CS56 Cluster: PyrE-like protein; n=5;
Methanomicrobiales|Rep: PyrE-like protein -
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498
/ JR1)
Length = 204
Score = 37.1 bits (82), Expect = 0.58
Identities = 24/63 (38%), Positives = 37/63 (58%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R + V+DVVT+G +L ET+ LR+ G AV L ++G E +G+ V SLF +
Sbjct: 145 QRCIIVDDVVTTGTTLSETIAFLRQHGATPV-AVWSLFDKRGAR---EIDGVPVHSLFVI 200
Query: 476 TNL 484
+ L
Sbjct: 201 SRL 203
>UniRef50_Q1ISH1 Cluster: Phosphoribosyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep:
Phosphoribosyltransferase - Acidobacteria bacterium
(strain Ellin345)
Length = 195
Score = 36.7 bits (81), Expect = 0.77
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 RNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER-EQGGASVL- 436
+N + K R + V+DV T+G S ++ + R+ G VT + ++ER E G +
Sbjct: 107 KNRIEGFKGKGSRVVIVDDVCTTGSSTIQAIAAAREFGFEVTGVMCLVERLEAMGRPAVE 166
Query: 437 -EANGIAVKSLFTLTNLVRMLH 499
EA G S+FT ++ VR+ H
Sbjct: 167 SEAGGAPFVSVFT-SDEVRVRH 187
>UniRef50_Q1ATP7 Cluster: Orotate phosphoribosyltransferase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Orotate
phosphoribosyltransferase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 178
Score = 36.3 bits (80), Expect = 1.0
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +1
Query: 91 PXLMVAVSHQLEQLIKXVHHXMICGVPYAALPLAVVISINTDRPMIMKRKETKLYATKKL 270
P L+ ++ LE L+ + GV A+PL V +++ T P ++ RKE K + T +
Sbjct: 44 PALLRDIAAGLEGLLP-AGVERLAGVELGAVPLVVAVALRTGMPYVIVRKEAKGHGTVRG 102
Query: 271 LEG 279
+EG
Sbjct: 103 IEG 105
Score = 34.7 bits (76), Expect = 3.1
Identities = 19/63 (30%), Positives = 31/63 (49%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R +EDV T+G + L + G V V VL+R +G A + G ++LF +
Sbjct: 111 ERVALIEDVTTTGTQAVRAARRLAEAGAEVAGVVAVLDRREGEAGE-DLQGFPFRALFRI 169
Query: 476 TNL 484
+L
Sbjct: 170 EDL 172
>UniRef50_Q66DQ2 Cluster: Adenine phosphoribosyltransferase; n=118;
Bacteria|Rep: Adenine phosphoribosyltransferase -
Yersinia pseudotuberculosis
Length = 187
Score = 36.3 bits (80), Expect = 1.0
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE-REQGGASVLEANGIAVKSL 466
+ L V+D++ +GG++ TV+ +R+ G V HA ++ E GG + L GI SL
Sbjct: 125 KVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSL 181
>UniRef50_Q3DVM1 Cluster: Phosphoribosyltransferase; n=2;
Chloroflexus|Rep: Phosphoribosyltransferase -
Chloroflexus aurantiacus J-10-fl
Length = 219
Score = 35.9 bits (79), Expect = 1.3
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Frame = +2
Query: 236 EKKQNYMPQRNYWRAYMKKI--KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE 409
E++ + +R + R Y I KR L VEDV+T+GGS+ VE + G +V +
Sbjct: 98 EEQHDTGKRRVFRRGYDAHIAGKRVLVVEDVITTGGSVRLVVEAVTAAGGVVVGVGALCN 157
Query: 410 REQGGASVLEANGIAVKSLFTLTNL 484
R GG S A + + L LT L
Sbjct: 158 R--GGIS---AADLGIPQLVALTEL 177
>UniRef50_Q6F6Z6 Cluster: Orotate phosphoribosyltransferase; n=23;
Gammaproteobacteria|Rep: Orotate
phosphoribosyltransferase - Acinetobacter sp. (strain
ADP1)
Length = 216
Score = 35.9 bits (79), Expect = 1.3
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEA-------NGIA 454
K+ ++DV+T+G ++ E V L+ G + ++ L+R++ G L A I
Sbjct: 122 KKVWIIDDVITAGTAIREVVTILKNAGATIAGVLVALDRQERGQGQLSAIQEVQQELEIP 181
Query: 455 VKSLFTLTNLVRMLHKAG 508
V +L T+ +L+ L G
Sbjct: 182 VHALITMKDLMNYLDAKG 199
>UniRef50_Q2GDM5 Cluster: Orotate phosphoribosyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Orotate
phosphoribosyltransferase - Neorickettsia sennetsu
(strain Miyayama)
Length = 206
Score = 35.5 bits (78), Expect = 1.8
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGA 427
+ L +EDVVT+ GS ++ ++ + G V A +++R +G A
Sbjct: 118 QNVLLIEDVVTTAGSSIDVIQKVHDRGANVIFAASIIDRSEGAA 161
>UniRef50_Q0LJI1 Cluster: Orotate phosphoribosyltransferase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Orotate
phosphoribosyltransferase - Herpetosiphon aurantiacus
ATCC 23779
Length = 217
Score = 35.5 bits (78), Expect = 1.8
Identities = 23/72 (31%), Positives = 37/72 (51%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
+R + +ED++++GGS L+ V LR+ +V + E S N V+ L TL
Sbjct: 117 QRVVVIEDLISTGGSSLDAVAGLRQINALVADCFAIFTYEM-EESKQRFNAAGVR-LMTL 174
Query: 476 TNLVRMLHKAGR 511
TNL +L A +
Sbjct: 175 TNLSTLLDVAAQ 186
>UniRef50_Q0EY52 Cluster: Orotate phosphoribosyltransferase; n=1;
Mariprofundus ferrooxydans PV-1|Rep: Orotate
phosphoribosyltransferase - Mariprofundus ferrooxydans
PV-1
Length = 193
Score = 35.5 bits (78), Expect = 1.8
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQG 421
R L VEDV+T+GGS+ E + +R+ G + + V++R G
Sbjct: 109 RLLVVEDVITTGGSVRECMVVVREHGGVPVKVLAVVDRAPG 149
>UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;
Oenococcus oeni PSU-1|Rep: Orotate
phosphoribosyltransferase - Oenococcus oeni (strain
BAA-331 / PSU-1)
Length = 211
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/84 (26%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 52 TPISFXLRVIVSHPXLMVAVSHQLEQLIKXVHHXM--ICGVPYAALPLAVVISINTDRPM 225
+PI R+ +++P + ++ L +LI + + I GV A +P A +S ++PM
Sbjct: 35 SPIYTDNRMTIAYPTIRKNIADGLSELIISNYPDVEIIGGVATAGIPHAAFVSDRMNKPM 94
Query: 226 IMKRKETKLYATKKLLEGVYEKNQ 297
I R + + + +K +EG N+
Sbjct: 95 IYVRSKARDHGSKHQIEGAQVDNK 118
>UniRef50_A4TUN0 Cluster: Orotate phosphoribosyltransferase; n=1;
Magnetospirillum gryphiswaldense|Rep: Orotate
phosphoribosyltransferase - Magnetospirillum
gryphiswaldense
Length = 277
Score = 35.5 bits (78), Expect = 1.8
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLERE--QGGASVLEANGIAVKSLFT 472
R + VED+ + G S + LR+ G V+HA +V G L G+ + L
Sbjct: 177 RVVLVEDLASDGASKVNFCNALREAGAEVSHAFVVFFYGVFPGALKALNETGVELSYLCN 236
Query: 473 LTNLVRMLHKAGRIDNDTVELI 538
+++ + + G D T+E +
Sbjct: 237 WWDVLEVAEQDGLFDRKTLEAV 258
>UniRef50_Q8ZJP7 Cluster: Orotate phosphoribosyltransferase; n=42;
cellular organisms|Rep: Orotate
phosphoribosyltransferase - Yersinia pestis
Length = 215
Score = 35.5 bits (78), Expect = 1.8
Identities = 14/48 (29%), Positives = 30/48 (62%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEA 442
R + V+DV+T+G ++ E++E + +G + +I L+R++ G + A
Sbjct: 119 RVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISA 166
>UniRef50_Q5WX86 Cluster: Orotate phosphoribosyltransferase; n=4;
Legionella pneumophila|Rep: Orotate
phosphoribosyltransferase - Legionella pneumophila
(strain Lens)
Length = 211
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER------EQGGASVLEANGIAVK 460
R + ++DV+T+G + E+ +++ G I+ +I L+R E+ S + GI V
Sbjct: 118 RTVIIDDVITAGTAFRESQTLIKENGGILRGVIIALDRCERGLTEKSTLSEIREQGIEVY 177
Query: 461 SLFTLTNLVRML 496
S+ L +L+ L
Sbjct: 178 SIINLFDLIEFL 189
>UniRef50_Q3XYF1 Cluster: Orotate phosphoribosyl transferase; n=3;
Bacilli|Rep: Orotate phosphoribosyl transferase -
Enterococcus faecium DO
Length = 209
Score = 35.1 bits (77), Expect = 2.3
Identities = 22/89 (24%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEG--LIVTHAVIVLEREQGGASVLEANGIAVKSLF 469
++ + +ED++++GGS+LE E ++EG ++ A+ E +G A+ +A I + +L
Sbjct: 116 QKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGKANFEKAE-IPLMTLT 174
Query: 470 TLTNLVRMLHKAGRIDNDTVELIFDHIKE 556
+ L+ + ID + L+ + K+
Sbjct: 175 NYSVLIEAALEDRYIDEQELTLLKEWKKD 203
>UniRef50_A4SX83 Cluster: Adenine phosphoribosyltransferase; n=1;
Polynucleobacter sp. QLW-P1DMWA-1|Rep: Adenine
phosphoribosyltransferase - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 172
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE-REQGGASVLEANGIAVKSL 466
+ L ++DV+ +GG+L+ + LR G V+ A+ +LE G+ LE N I KS+
Sbjct: 113 KVLLIDDVLATGGTLIAADKLLRSAGFQVSGAITLLEIAVLNGSEQLEKNHIHHKSV 169
>UniRef50_A1UNJ3 Cluster: Orotate phosphoribosyltransferase; n=6;
Mycobacterium|Rep: Orotate phosphoribosyltransferase -
Mycobacterium sp. (strain KMS)
Length = 192
Score = 35.1 bits (77), Expect = 2.3
Identities = 17/62 (27%), Positives = 33/62 (53%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTLT 478
R L V+DV+++GGS + + G +VT + +++R A++ G+ +L T
Sbjct: 123 RVLLVDDVISTGGSTALAFDRVVAAGAVVTGVIPMVDRGDVAATLFAERGVPFAALVTYR 182
Query: 479 NL 484
+L
Sbjct: 183 DL 184
>UniRef50_UPI00006CB7C9 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1166
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/69 (23%), Positives = 34/69 (49%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
++ L +V SGG T + ++ + ++ + QGG + AN I+ + + +
Sbjct: 110 EKTLTQPNVNPSGGINTNTASNVNNSNSLIINHILDSTKSQGGTININANNISFHNQYNI 169
Query: 476 TNLVRMLHK 502
TNLV +++
Sbjct: 170 TNLVSQMNR 178
>UniRef50_Q7MSB1 Cluster: Putative uncharacterized protein; n=1;
Wolinella succinogenes|Rep: Putative uncharacterized
protein - Wolinella succinogenes
Length = 194
Score = 34.7 bits (76), Expect = 3.1
Identities = 14/33 (42%), Positives = 25/33 (75%)
Frame = +2
Query: 287 KKIKRALXVEDVVTSGGSLLETVETLRKEGLIV 385
KKI+ A+ ++D+VT+G ++LE + L +EG+ V
Sbjct: 147 KKIESAVLIDDLVTTGSTMLEAKKVLEREGVEV 179
>UniRef50_A6PMI4 Cluster: Orotate phosphoribosyltransferase; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Orotate
phosphoribosyltransferase - Victivallis vadensis ATCC
BAA-548
Length = 188
Score = 34.7 bits (76), Expect = 3.1
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGA 427
R L EDVVT GG + +T++ R G + ++++R G A
Sbjct: 109 RILVAEDVVTKGGRVQQTIDLARSFGAEIVGIAVIVDRSGGDA 151
>UniRef50_Q1UZB0 Cluster: Orotate phosphoribosyltransferase; n=3;
Bacteria|Rep: Orotate phosphoribosyltransferase -
Candidatus Pelagibacter ubique HTCC1002
Length = 200
Score = 34.3 bits (75), Expect = 4.1
Identities = 17/58 (29%), Positives = 33/58 (56%)
Frame = +2
Query: 281 YMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIA 454
++KK + L +EDV+T+G S LE V+ + K G + +++R + ++ N I+
Sbjct: 111 HIKKGSKVLIIEDVITTGKSSLECVKLITKPGAKLIGFASIIDRSTKNSLKIKKNIIS 168
>UniRef50_A5EY64 Cluster: Orotate phosphoribosyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: Orotate
phosphoribosyltransferase - Dichelobacter nodosus
(strain VCS1703A)
Length = 221
Score = 34.3 bits (75), Expect = 4.1
Identities = 23/80 (28%), Positives = 46/80 (57%), Gaps = 8/80 (10%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER-EQGGASVLEA-------NGI 451
K+ L V+DV+T+G ++ +++ L +E + VI L+R E+ G S L A N +
Sbjct: 122 KKVLLVDDVLTAGTAVRQSLALLAQEQAMPVGLVIALDRQEKVGDSNLSALKQFSVENQL 181
Query: 452 AVKSLFTLTNLVRMLHKAGR 511
+++ TL +L+ + ++G+
Sbjct: 182 QTRAIITLDDLMTFVKESGK 201
>UniRef50_A5JEM2 Cluster: Chloroplast RNA-polymerase sigma factor
precursor; n=1; Heterosigma akashiwo|Rep: Chloroplast
RNA-polymerase sigma factor precursor - Heterosigma
akashiwo
Length = 404
Score = 34.3 bits (75), Expect = 4.1
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = +2
Query: 245 QNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGG 424
+NY+PQ + + Y+K ++ D++T+ +L T + K G+ + A++ LE+ G
Sbjct: 66 KNYLPQSDTMKEYVKDLRTV----DMLTAQEEILLTRQI--KRGMEIEKALVTLEKTLGR 119
Query: 425 ASVLE--ANGIAVKSLFTL-TNLVRMLHKAGRIDNDTVELIFDHIKECQF 565
E N + +KS+ + NL R I N + L+ K Q+
Sbjct: 120 KPTEEEWVNFVGLKSIDDIRKNLKRASKSKSAIINANLRLVVSTAKAYQY 169
>UniRef50_A1Z907 Cluster: CG8529-PE, isoform E; n=9; Diptera|Rep:
CG8529-PE, isoform E - Drosophila melanogaster (Fruit
fly)
Length = 670
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = -2
Query: 483 KLVNVKSDFTAIPFASSTLAPPCSRSSTITACVTIKPSLRKVSTVSSKLPPD 328
+L + SD + A+ + PP R++T TA V+ PSL +S + L PD
Sbjct: 592 QLNQISSDMRSAFAANGSATPPPMRTTTATANVSAIPSLNPISNQNPNLNPD 643
>UniRef50_Q2QAL5 Cluster: Orotate phosphoribosyltransferase-like
protein; n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Orotate phosphoribosyltransferase-like
protein - uncultured marine group II euryarchaeote
HF70_39H11
Length = 63
Score = 34.3 bits (75), Expect = 4.1
Identities = 13/44 (29%), Positives = 32/44 (72%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGA 427
++ + V+DV++SG ++ +T++TL++EG V +V+++ + + A
Sbjct: 5 RKVVVVDDVLSSGETMRKTIKTLQEEGADVALSVVMVNKTEENA 48
>UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54;
Bacilli|Rep: Orotate phosphoribosyltransferase -
Bacillus halodurans
Length = 210
Score = 34.3 bits (75), Expect = 4.1
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 RTPISFXLRVIVSHPXLMVAVSHQLEQLIKX--VHHXMICGVPYAALPLAVVISINTDRP 222
++PI R+ + +P + +++ EQLI+ ++ G A +P A +S P
Sbjct: 30 KSPIYCDNRLTMGYPHIRQSIAEGFEQLIRSHFPEVTVVAGTATAGIPHAAWVSDRLQAP 89
Query: 223 MIMKRKETKLYATKKLLEG 279
M+ R ++K + + +EG
Sbjct: 90 MVYVRSKSKGHGKQNQIEG 108
Score = 33.1 bits (72), Expect = 9.5
Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Frame = +2
Query: 233 REKKQNYMPQRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
R K + + Q N + R + +ED++++GGS+++ + LR+ G V V +
Sbjct: 94 RSKSKGHGKQ-NQIEGKLSSKDRVVIIEDLISTGGSVIQAADALREAGADVLGVVAIFTY 152
Query: 413 E-QGGASVLEANGIAVKSLFTLTNLVRMLHKAGRIDNDTVE 532
+ G LEA + L L+ + + G I + ++
Sbjct: 153 GLEKGQDQLEAANLPSYVLTDYPTLLDVAIRRGDISEEELQ 193
>UniRef50_Q5QYM7 Cluster: Orotate phosphoribosyltransferase; n=9;
Gammaproteobacteria|Rep: Orotate
phosphoribosyltransferase - Idiomarina loihiensis
Length = 214
Score = 33.9 bits (74), Expect = 5.4
Identities = 14/48 (29%), Positives = 29/48 (60%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEA 442
+ + V+DV+T+G ++ E +E + G ++ +I L+R++ G L A
Sbjct: 119 KVMLVDDVITAGTAIREAMEIVETNGAELSGVLIALDRQEKGKGELSA 166
>UniRef50_A7DHQ5 Cluster: Orotate phosphoribosyltransferase
precursor; n=3; Alphaproteobacteria|Rep: Orotate
phosphoribosyltransferase precursor - Methylobacterium
extorquens PA1
Length = 227
Score = 33.9 bits (74), Expect = 5.4
Identities = 21/59 (35%), Positives = 34/59 (57%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEANGIAVKSLFTL 475
RA+ VED+VT+G S E + +L+ E V A +++R G ++ G+ + SL TL
Sbjct: 143 RAVIVEDIVTTGLSARECLASLKDEAGEVVGAACLIDRSGGRGAI----GLPLLSLVTL 197
>UniRef50_Q8UI98 Cluster: Orotate phosphoribosyltransferase; n=4;
Alphaproteobacteria|Rep: Orotate
phosphoribosyltransferase - Agrobacterium tumefaciens
(strain C58 / ATCC 33970)
Length = 232
Score = 33.9 bits (74), Expect = 5.4
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAV 397
R L +ED+ T+GGS+ ++ +R G IV H +
Sbjct: 128 RVLVIEDLTTAGGSMFTFIDAIRAAGGIVDHGI 160
>UniRef50_Q4HEY3 Cluster: Transformation system protein; n=12;
Campylobacter|Rep: Transformation system protein -
Campylobacter coli RM2228
Length = 191
Score = 33.5 bits (73), Expect = 7.2
Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 284 MKKIKR-ALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE 409
+KKI + V+D+V+SG SLLE + L K + V AV++ +
Sbjct: 146 LKKINNPVILVDDIVSSGSSLLEAKQFLEKNKISVLFAVVLAD 188
>UniRef50_A1ZTS6 Cluster: Orotate phosphoribosyltransferase; n=1;
Microscilla marina ATCC 23134|Rep: Orotate
phosphoribosyltransferase - Microscilla marina ATCC
23134
Length = 218
Score = 33.5 bits (73), Expect = 7.2
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +2
Query: 260 QRNYWRAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLE 439
+ N + K ++ + +EDV+++GGS ++ VE LR+ G+ V V + G V+E
Sbjct: 108 KENLVEGKLTKGQKVVVIEDVLSTGGSSIKAVEALREAGVEVLGIVAMFTY---GFDVME 164
Query: 440 ANGIAVKSLF-TLTNLVRML 496
N F TL+N ++
Sbjct: 165 QNMADADLKFNTLSNYTTLV 184
>UniRef50_Q16T77 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 860
Score = 33.5 bits (73), Expect = 7.2
Identities = 22/45 (48%), Positives = 26/45 (57%)
Frame = -2
Query: 426 APPCSRSSTITACVTIKPSLRKVSTVSSKLPPDVTTSSTXKARLI 292
+P S SST +A VT P+ R VST S L P TTSS + R I
Sbjct: 309 SPGSSGSSTASATVTT-PTTR-VSTTQSSLSPTATTSSPKRVRTI 351
>UniRef50_A7I2M8 Cluster: Transformation system protein; n=1;
Campylobacter hominis ATCC BAA-381|Rep: Transformation
system protein - Campylobacter hominis (strain ATCC
BAA-381 / LMG 19568 / NCTC 13146 /CH001A)
Length = 233
Score = 33.1 bits (72), Expect = 9.5
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 305 LXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQ 418
+ V+D+VT+G SLLE +TL G V +++ E+
Sbjct: 195 ILVDDIVTTGSSLLEAKKTLENAGFSVLFGLVLANAEE 232
>UniRef50_A7BCL9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 179
Score = 33.1 bits (72), Expect = 9.5
Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 296 KRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQ-GGASVL 436
+R L ++DV+ +GG+ V+ LR+ G V ++LE + GG SVL
Sbjct: 121 QRVLIIDDVLATGGTANAAVKLLRQCGASVEAVAVLLELDALGGRSVL 168
>UniRef50_A3TGP0 Cluster: Putative uncharacterized protein; n=2;
Janibacter sp. HTCC2649|Rep: Putative uncharacterized
protein - Janibacter sp. HTCC2649
Length = 287
Score = 33.1 bits (72), Expect = 9.5
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = -2
Query: 456 TAIPFASSTLAPPCSRSSTITACVTIKPSLRKVSTVSSKLPPDVTTSST 310
T P A+ T S S+T+TA T PS +T +S P T+SST
Sbjct: 82 TPTPEATPTTTSSASPSATVTATPTAVPSSTPSATATSTAKPSRTSSST 130
>UniRef50_A7AV27 Cluster: Orotate phosphoribosyltransferase; n=1;
Babesia bovis|Rep: Orotate phosphoribosyltransferase -
Babesia bovis
Length = 196
Score = 33.1 bits (72), Expect = 9.5
Identities = 15/48 (31%), Positives = 29/48 (60%)
Frame = +2
Query: 299 RALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLEREQGGASVLEA 442
R + ++DV+TSG +L + ++ + G+ V V++L RE +V +A
Sbjct: 125 RVVVIDDVLTSGKALFKGLDMIEPLGVKVVGVVVILNRELNYGTVAKA 172
>UniRef50_A2QTV9 Cluster: Contig An09c0090, complete genome; n=1;
Aspergillus niger|Rep: Contig An09c0090, complete genome
- Aspergillus niger
Length = 321
Score = 33.1 bits (72), Expect = 9.5
Identities = 18/52 (34%), Positives = 26/52 (50%)
Frame = -2
Query: 477 VNVKSDFTAIPFASSTLAPPCSRSSTITACVTIKPSLRKVSTVSSKLPPDVT 322
VN D +IP S+ +APP + S+ T+K S K+ + SK P T
Sbjct: 90 VNSVEDIDSIPATSTPIAPPSAASTPTPEPTTLKQSTIKIQSPPSKETPKDT 141
>UniRef50_P21846 Cluster: Orotate phosphoribosyltransferase; n=7;
Pezizomycotina|Rep: Orotate phosphoribosyltransferase -
Trichoderma reesei (Hypocrea jecorina)
Length = 236
Score = 33.1 bits (72), Expect = 9.5
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +2
Query: 290 KIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLER 412
K KR L V+DV+T+G + + +E + KEG V+ L+R
Sbjct: 130 KGKRVLIVDDVITAGTAKRDAIEKITKEGRHRRGIVVALDR 170
>UniRef50_P12426 Cluster: Adenine phosphoribosyltransferase; n=6;
Endopterygota|Rep: Adenine phosphoribosyltransferase -
Drosophila melanogaster (Fruit fly)
Length = 182
Score = 33.1 bits (72), Expect = 9.5
Identities = 13/45 (28%), Positives = 30/45 (66%)
Frame = +2
Query: 275 RAYMKKIKRALXVEDVVTSGGSLLETVETLRKEGLIVTHAVIVLE 409
++ +K ++ + V+D++ +GGSL+ E + K G +V +++V+E
Sbjct: 118 KSAIKPGQKVVVVDDLLATGGSLVAATELIGKVGGVVVESLVVME 162
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 688,418,358
Number of Sequences: 1657284
Number of extensions: 12262790
Number of successful extensions: 29563
Number of sequences better than 10.0: 119
Number of HSP's better than 10.0 without gapping: 28295
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29498
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 77882636090
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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