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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fdpeP01_F_J21
         (929 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC142946-1|AAI42947.1|  457|Homo sapiens RCC2 protein protein.        145   2e-34
BC053908-1|AAH53908.1|  522|Homo sapiens RCC2 protein protein.        145   2e-34
BC042141-1|AAH42141.1|  522|Homo sapiens regulator of chromosome...   145   2e-34
AJ421269-1|CAD13148.1|  522|Homo sapiens RCC1-like protein protein.   145   2e-34
AB040903-1|BAA95994.1|  564|Homo sapiens KIAA1470 protein protein.    145   2e-34
AL359612-1|CAB94882.1|  333|Homo sapiens hypothetical protein pr...   134   3e-31
BC004933-1|AAH04933.1|  351|Homo sapiens RCC2 protein protein.        111   5e-24
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.                81   6e-15
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.                   75   3e-13
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas...    74   9e-13
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei...    74   9e-13
X97668-1|CAA66258.1|  815|Homo sapiens XLRP3 protein.                  73   1e-12
U57629-1|AAC50481.1|  815|Homo sapiens retinitis pigmentosa GTPa...    73   1e-12
BC031624-1|AAH31624.1|  480|Homo sapiens RPGR protein protein.         73   1e-12
AL606748-2|CAI95407.1|  815|Homo sapiens retinitis pigmentosa GT...    73   1e-12
AK223491-1|BAD97211.1|  815|Homo sapiens retinitis pigmentosa GT...    73   1e-12
AJ318463-1|CAC86116.1|  815|Homo sapiens retinitis pigmentosa GT...    73   1e-12
AJ238395-1|CAB54002.1|  646|Homo sapiens RPGR protein protein.         73   1e-12
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p...    71   5e-12
AY650033-1|AAV66579.1|  979|Homo sapiens HECT and RCC1 containin...    71   5e-12
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin...    71   5e-12
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p...    71   5e-12
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p...    71   5e-12
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.               71   6e-12
BC038960-1|AAH38960.1|  368|Homo sapiens HERC3 protein protein.        71   6e-12
AC098582-1|AAY41038.1|  382|Homo sapiens unknown protein.              71   6e-12
BC029052-1|AAH29052.1|  551|Homo sapiens regulator of chromosome...    70   1e-11
AY341245-1|AAP88928.1|  551|Homo sapiens chromosome condensation...    70   1e-11
AL157813-1|CAH70795.1|  551|Homo sapiens regulator of chromosome...    70   1e-11
AF060219-1|AAC79987.1|  551|Homo sapiens RCC1-like G exchanging ...    70   1e-11
AC004460-2|AAC06339.1|  371|Homo sapiens WUGSC:H_DJ1086D14.2 pro...    70   1e-11
AB209543-1|BAD92780.1|  556|Homo sapiens RCC1-like G exchanging ...    70   1e-11
AF224249-1|AAO27475.1|  328|Homo sapiens HERC2 protein.                70   1e-11
BC038104-1|AAH38104.1|  355|Homo sapiens RCBTB1 protein protein.       69   2e-11
AL139321-5|CAH71047.1|  531|Homo sapiens regulator of chromosome...    69   2e-11
AK096654-1|BAC04833.1|  531|Homo sapiens protein ( Homo sapiens ...    69   2e-11
AJ319660-1|CAC40027.1|  531|Homo sapiens guanine nucleotide exch...    69   2e-11
AF334406-1|AAK38372.1|  531|Homo sapiens CLLL7 protein protein.        69   2e-11
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t...    68   4e-11
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t...    68   4e-11
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga...    68   4e-11
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga...    68   4e-11
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.          68   4e-11
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.     68   4e-11
AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4 p...    68   6e-11
AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4 p...    68   6e-11
AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.     68   6e-11
BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.        64   5e-10
BC112101-1|AAI12102.1|  979|Homo sapiens NIMA related kinase 9 p...    63   2e-09
BC093881-1|AAH93881.1|  979|Homo sapiens NIMA (never in mitosis ...    63   2e-09
AY080896-1|AAL87410.1|  979|Homo sapiens NIMA-family kinase NERC...    63   2e-09
AY048580-1|AAL05428.1|  979|Homo sapiens NIMA-related kinase Nek...    63   2e-09
AC007055-4|AAD31939.1|  414|Homo sapiens protein ( Homo sapiens ...    63   2e-09
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.     63   2e-09
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p...    61   6e-09
AY653203-1|AAV66897.1|  322|Homo sapiens truncated HERC6 protein.      61   6e-09
AY653202-1|AAV66896.1|  364|Homo sapiens truncated HERC6 protein.      61   6e-09
AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant pr...    61   6e-09
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.                61   6e-09
AF225407-1|AAO27483.1|  409|Homo sapiens HERC2 protein.                60   9e-09
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with...    60   1e-08
BC029174-1|AAH29174.1|  812|Homo sapiens ALS2 protein protein.         58   3e-08
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.                58   3e-08
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.              58   3e-08
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.                 58   3e-08
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.     58   3e-08
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.         58   6e-08
BC065375-1|AAH65375.1|  458|Homo sapiens secretion regulating gu...    57   8e-08
AJ243951-1|CAB60833.1|  288|Homo sapiens deafness locus associat...    57   8e-08
AJ243950-1|CAB60832.1|  458|Homo sapiens deafness locus associat...    57   8e-08
BC113705-1|AAI13706.1|  692|Homo sapiens NIMA (never in mitosis ...    56   2e-07
BC112240-1|AAI12241.1|  692|Homo sapiens NIMA-related kinase 8 p...    56   2e-07
AY267371-1|AAP04006.1|  692|Homo sapiens NIMA-family kinase NEK8...    56   2e-07
AY242354-1|AAO88243.1|  692|Homo sapiens NIMA-related kinase 12a...    56   2e-07
AK023024-1|BAB14362.1|  396|Homo sapiens protein ( Homo sapiens ...    54   7e-07
AK092403-1|BAC03879.1|  184|Homo sapiens protein ( Homo sapiens ...    53   1e-06
AB053306-1|BAB69015.1|  396|Homo sapiens ALS2 protein.                 53   1e-06
X12654-1|CAA31182.1|  421|Homo sapiens protein ( Human mRNA for ...    53   2e-06
X06130-1|CAA29496.1|  421|Homo sapiens protein ( Human mRNA for ...    53   2e-06
D00591-1|BAA00469.1|  421|Homo sapiens RCC1 protein.                   53   2e-06
CR407693-1|CAG28621.1|  421|Homo sapiens CHC1 protein.                 53   2e-06
BC069198-1|AAH69198.1|  452|Homo sapiens regulator of chromosome...    53   2e-06
BC036903-1|AAH36903.1|  421|Homo sapiens regulator of chromosome...    53   2e-06
BC010067-1|AAH10067.1|  421|Homo sapiens regulator of chromosome...    53   2e-06
BC007300-1|AAH07300.1|  421|Homo sapiens regulator of chromosome...    53   2e-06
AL513497-2|CAI22287.1|  421|Homo sapiens regulator of chromosome...    53   2e-06
AF498924-1|AAM21072.1|  421|Homo sapiens regulator of chromosome...    53   2e-06
BC040695-1|AAH40695.1|  358|Homo sapiens WBSCR16 protein protein.      52   3e-06
BC032712-1|AAH32712.1|  454|Homo sapiens WBSCR16 protein protein.      52   3e-06
BC019008-1|AAH19008.1|  464|Homo sapiens Williams-Beuren syndrom...    52   3e-06
BC007823-1|AAH07823.1|  464|Homo sapiens Williams-Beuren syndrom...    52   3e-06
AF410455-1|AAM62304.1|  464|Homo sapiens RCC1-like G exchanging ...    52   3e-06
BC113826-1|AAI13827.1|  244|Homo sapiens RCCD1 protein protein.        44   6e-04
AY650032-1|AAV66578.1|  117|Homo sapiens HECT and RCC1 containin...    44   8e-04
AY650034-1|AAV66580.1|  110|Homo sapiens HECT and RCC1 containin...    41   0.006
AF225404-1|AAO27482.1|  259|Homo sapiens HERC2 protein.                35   0.37 
BC067293-1|AAH67293.1|  580|Homo sapiens F-box protein 24 protein.     32   3.4  
AC069281-1|AAP21863.1|  580|Homo sapiens unknown protein.              32   3.4  

>BC142946-1|AAI42947.1|  457|Homo sapiens RCC2 protein protein.
          Length = 457

 Score =  145 bits (351), Expect = 2e-34
 Identities = 77/181 (42%), Positives = 103/181 (56%), Gaps = 7/181 (3%)
 Frame = +2

Query: 233 KTPGVLMIAGLVSWDLTAR----RDNNPTKRTHPNLYTFHKF---TDRRYRLIVSGCTAG 391
           K  G L+I G  +WDL  R    R     +    NL+  H++      R R +VSG  A 
Sbjct: 36  KCKGQLLIFGATNWDLIGRKEVPRQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 95

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 96  HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 155

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFG
Sbjct: 156 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFG 214

Query: 752 C 754
           C
Sbjct: 215 C 215


>BC053908-1|AAH53908.1|  522|Homo sapiens RCC2 protein protein.
          Length = 522

 Score =  145 bits (351), Expect = 2e-34
 Identities = 76/181 (41%), Positives = 105/181 (58%), Gaps = 7/181 (3%)
 Frame = +2

Query: 233 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 391
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFG
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFG 279

Query: 752 C 754
           C
Sbjct: 280 C 280


>BC042141-1|AAH42141.1|  522|Homo sapiens regulator of chromosome
           condensation 2 protein.
          Length = 522

 Score =  145 bits (351), Expect = 2e-34
 Identities = 76/181 (41%), Positives = 105/181 (58%), Gaps = 7/181 (3%)
 Frame = +2

Query: 233 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 391
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFG
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFG 279

Query: 752 C 754
           C
Sbjct: 280 C 280


>AJ421269-1|CAD13148.1|  522|Homo sapiens RCC1-like protein protein.
          Length = 522

 Score =  145 bits (351), Expect = 2e-34
 Identities = 76/181 (41%), Positives = 105/181 (58%), Gaps = 7/181 (3%)
 Frame = +2

Query: 233 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 391
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFG
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFG 279

Query: 752 C 754
           C
Sbjct: 280 C 280


>AB040903-1|BAA95994.1|  564|Homo sapiens KIAA1470 protein protein.
          Length = 564

 Score =  145 bits (351), Expect = 2e-34
 Identities = 76/181 (41%), Positives = 105/181 (58%), Gaps = 7/181 (3%)
 Frame = +2

Query: 233 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 391
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 143 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 202

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 262

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFG
Sbjct: 263 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFG 321

Query: 752 C 754
           C
Sbjct: 322 C 322


>AL359612-1|CAB94882.1|  333|Homo sapiens hypothetical protein
           protein.
          Length = 333

 Score =  134 bits (325), Expect = 3e-31
 Identities = 65/136 (47%), Positives = 85/136 (62%)
 Frame = +2

Query: 347 TDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNII 526
           T  R R +VSG  A HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+
Sbjct: 2   TRGRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIV 61

Query: 527 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPX 706
            AA GR+HTL +T+TG V+A G+NK GQ GLGN T  +  P +I YNG PI K+ C    
Sbjct: 62  SAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-E 120

Query: 707 XXXXXXCNGNLHSFGC 754
                 C GNL+SFGC
Sbjct: 121 FSMIMDCKGNLYSFGC 136


>BC004933-1|AAH04933.1|  351|Homo sapiens RCC2 protein protein.
          Length = 351

 Score =  111 bits (266), Expect = 5e-24
 Identities = 53/110 (48%), Positives = 68/110 (61%)
 Frame = +2

Query: 425 YTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 604
           +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+TG V+A G+NK 
Sbjct: 1   WSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKM 60

Query: 605 GQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
           GQ GLGN T  +  P +I YNG PI K+ C          C GNL+SFGC
Sbjct: 61  GQLGLGNQTDAVPSPAQIMYNGQPITKMACGA-EFSMIMDCKGNLYSFGC 109



 Score = 50.4 bits (115), Expect = 9e-06
 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVG 541
           ++ + C   H++ ++E G  + FG N  GQLG G+  T +VP     +  G+ I   A G
Sbjct: 33  IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQ-TDAVPSPAQIMYNGQPITKMACG 91

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN 667
              ++ +   G +Y+ G  + GQ G  +    I +  RI+Y+
Sbjct: 92  AEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYD 133


>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
          Length = 4834

 Score = 81.0 bits (191), Expect = 6e-15
 Identities = 45/106 (42%), Positives = 61/106 (57%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
            C A  S+ +++ G  +T+G+    +LG G  V    P++V  L+GK I+H AVG  H L 
Sbjct: 3212 CGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLA 3271

Query: 560  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
            VTD+G VYA GDN  GQ G G TT    KPT ++   G  I +V C
Sbjct: 3272 VTDSGQVYAWGDNDHGQQGNGTTTVN-RKPTLVQGLEGQKITRVAC 3316



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 2/107 (1%)
 Frame = +2

Query: 380  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH--HT 553
            C + HS  ++  GE YT+G    G+LG GD  T+  P++V  L G  +I  A G     T
Sbjct: 3106 CGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQT 3165

Query: 554  LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
            L +TD G V++ GD   G+ G G +    +     + NG  + ++ C
Sbjct: 3166 LALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIEC 3212



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 6/111 (5%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHT 553
           C + +S  ++ EGE YT+GR   G+LG G +   ++P LV  LKG  +I  A G     T
Sbjct: 558 CGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQT 617

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNGTPIVKVGC 694
           L VT+ G V++ GD   G+ G G +    TP++++    K     +VKV C
Sbjct: 618 LAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIE----KLQDLDVVKVRC 664



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 37/106 (34%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
            C +  SV +++ G  YT+G+    +LG G       P  V  L+GK +I  A G  H + 
Sbjct: 4204 CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVC 4263

Query: 560  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
             T+ G VY  GDN  GQ G G TT  I +P  +    G  + +V C
Sbjct: 4264 CTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLVAALQGKKVNRVAC 4308



 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
            H + +S EGE Y++G    G+LG G+      P ++  L+G  ++  A G  H+  VT  
Sbjct: 4050 HCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAA 4109

Query: 572  GCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
            G +Y  G  + G+ G  ++  Q LKP  ++   G  +V + C
Sbjct: 4110 GDLYTWGKGRYGRLGHSDSEDQ-LKPKLVEALQGHRVVDIAC 4150



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +2

Query: 392  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHTLFVT 565
            HS  V+  G+ YT+G+   G+LG  D+  +  P+LV  L+G  ++  A G     TL +T
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 4161

Query: 566  DTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
            D   V++ GD   G+ G G +    +        G  +VKV C
Sbjct: 4162 DDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVEC 4204



 Score = 54.0 bits (124), Expect = 7e-07
 Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELK----GKNIIHAAVGRHHTLF 559
           H + ++  GE Y++G    G+LG GDTV    P+++        GK+++H A G  ++  
Sbjct: 506 HYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAA 565

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
           +T  G +Y  G    G+ G G++  + +        G  ++ V C
Sbjct: 566 ITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVAC 610



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/55 (47%), Positives = 31/55 (56%)
 Frame = +2

Query: 392  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
            H V  +E+GE YT+G N  GQLG G T     P LV  L+GK +   A G  HTL
Sbjct: 4260 HCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 4314



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 23/77 (29%), Positives = 42/77 (54%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C +  S+ ++++G+ Y++G+    +LG G       P+L+  L+GK +I  A G  H L 
Sbjct: 664 CGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLA 723

Query: 560 VTDTGCVYACGDNKSGQ 610
           +T+   V++ G N   Q
Sbjct: 724 LTEDSEVHSWGSNDQCQ 740



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/89 (30%), Positives = 41/89 (46%)
 Frame = +2

Query: 419  EAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDN 598
            + + +G N   QLG        VP     L   N++  A G      VT  G VYACG+ 
Sbjct: 2960 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEA 3019

Query: 599  KSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
             +G+ GLG ++  +  P +I    + +VK
Sbjct: 3020 TNGRLGLGISSGTVPIPRQITALSSYVVK 3048



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 20/85 (23%), Positives = 43/85 (50%)
 Frame = +2

Query: 368 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 547
           +  G     ++ V+E G+ +++G    G+LG G +     P+L+ +L+  +++    G  
Sbjct: 608 VACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQ 667

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLG 622
            ++ +T  G VY+ G   + + G G
Sbjct: 668 FSIALTKDGQVYSWGKGDNQRLGHG 692



 Score = 41.1 bits (92), Expect = 0.006
 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
 Frame = +2

Query: 368  IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 547
            +  G     ++ +++EG  +++G    G+LG G +   ++P+ +  L G+ +     G  
Sbjct: 3156 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQ 3215

Query: 548  HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
             +L +T +G V+  G     + G G+    + KP  ++   G  IV V
Sbjct: 3216 FSLALTKSGVVWTWGKGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHV 3262



 Score = 40.3 bits (90), Expect = 0.010
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHT 553
           C     +++S  G  YT   N+       DT+    P+LV  L  +NI+  A     HH 
Sbjct: 458 CAEKRFLILSRNGRVYTQAYNS-------DTLA---PQLVQGLASRNIVKIAAHSDGHHY 507

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTT----PQILKPTRIKYNGTPIVKVGC 694
           L +  TG VY+ G    G+ G G+T     P+++     K  G  +V + C
Sbjct: 508 LALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIAC 558



 Score = 35.1 bits (77), Expect = 0.37
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
 Frame = +2

Query: 416  GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF-VTDTGCVYACG 592
            G  Y +G N  GQLG  +     VP     L     +   +G   TLF VT  G +YA G
Sbjct: 3952 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQ-LIGGEQTLFAVTADGKLYATG 4010

Query: 593  DNKSGQCGLGNT----TPQILK 646
                G+ G+G T    TP +L+
Sbjct: 4011 YGAGGRLGIGGTESVSTPTLLE 4032



 Score = 34.7 bits (76), Expect = 0.48
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
 Frame = +2

Query: 404  VSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV---GRHHTLFVTDT 571
            V+ EG+ Y  G    G+LG G  + T  +P  +  L    +   AV   GRH T    D 
Sbjct: 3007 VTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVD- 3065

Query: 572  GCVYACGDNKSGQCG 616
            G V++ G+   G+ G
Sbjct: 3066 GKVFSWGEGDDGKLG 3080


>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
          Length = 4861

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 46/131 (35%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +2

Query: 365  LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
            ++   C   HS +V+ +G+ +TFG    G+LG G+T  + +PE V  L+G  I   A G 
Sbjct: 4136 VVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGL 4195

Query: 545  HHTLFVT-DTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGCXCPXXXXX 718
            +HTL V+ D   V+A GD   G+ GLGN+T +   P +I    G  I KV C        
Sbjct: 4196 NHTLAVSADGSMVWAFGDGDYGKLGLGNSTAK-SSPQKIDVLCGIGIKKVACGTQFSVAL 4254

Query: 719  XXCNGNLHSFG 751
               +G++++FG
Sbjct: 4255 TK-DGHVYTFG 4264



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 33/111 (29%), Positives = 60/111 (54%)
 Frame = +2

Query: 362  RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
            +L+ S  + GHS+ ++E GE +++G    G+LG G++  +  P  +  L+G+ ++  + G
Sbjct: 4083 QLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCG 4142

Query: 542  RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
              H+  VT  G ++  G+   G+ GLGNT+ + L        G  I +V C
Sbjct: 4143 FKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVAC 4193



 Score = 64.9 bits (151), Expect = 4e-10
 Identities = 36/122 (29%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  V+E+GE YT+G    G+LG GD+ +R++P LV ++   N+   + G  HT+ ++  
Sbjct: 522 HSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDI--SNVGEVSCGSSHTIALSKD 579

Query: 572 G-CVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSF 748
           G  V++ G   +G+ G G+T  ++ KP  I+      ++  C            G ++++
Sbjct: 580 GRTVWSFGGGDNGKLGHGDTN-RVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAW 638

Query: 749 GC 754
           GC
Sbjct: 639 GC 640



 Score = 64.5 bits (150), Expect = 5e-10
 Identities = 35/93 (37%), Positives = 49/93 (52%)
 Frame = +2

Query: 380  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
            C    SV ++++G  YTFG++    L  G     + P+ +P L G  I   AVG  HTL 
Sbjct: 4246 CGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLA 4305

Query: 560  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            +   G VYA G N  GQ GLG+T   + +PT +
Sbjct: 4306 LASNGDVYAWGSNSEGQLGLGHTN-HVREPTLV 4337



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSV-PELVPELKGKNIIHAAVGRHHTLFVTDT 571
           S+ ++  G+ Y +G  AC  LG G +   ++ P+L+ EL    I+  ++G  H L ++  
Sbjct: 626 SLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHD 683

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             VYA G+N  GQCG GN+T  I KP ++
Sbjct: 684 NEVYAWGNNSMGQCGQGNSTGPITKPKKV 712



 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 29/92 (31%), Positives = 55/92 (59%), Gaps = 1/92 (1%)
 Frame = +2

Query: 389 GHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP-ELKGKNIIHAAVGRHHTLFVT 565
           GH++  + EGE +++G    G+LG G++ T+  P+L+   L+GK ++  + G  H+  VT
Sbjct: 468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVT 527

Query: 566 DTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + G +Y  G+   G+ G G++  + + PT +K
Sbjct: 528 EDGELYTWGEGDFGRLGHGDSNSRNI-PTLVK 558



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEA-YTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           C + H++ +S++G   ++FG    G+LG GDT     P+++  L+G  I     G   +L
Sbjct: 568 CGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSL 627

Query: 557 FVTDTGCVYACGDNKSGQC-GLGNTTPQILKPTRIK 661
            +T TG VYA G    G C G G++    L+P  I+
Sbjct: 628 ALTSTGQVYAWG---CGACLGCGSSEATALRPKLIE 660



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
 Frame = +2

Query: 386  AGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-HHTLFV 562
            A H++ ++  G+ Y +G N+ GQLG G T     P LV  L+GKN+   + GR H   + 
Sbjct: 4300 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 4359

Query: 563  TDTGCVYACGDNKSGQCGLGNTTP 634
                   A G +   Q GL +T P
Sbjct: 4360 APPVPPRAPGVSVPLQLGLPDTVP 4383



 Score = 47.2 bits (107), Expect = 8e-05
 Identities = 28/83 (33%), Positives = 40/83 (48%)
 Frame = +2

Query: 389 GHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           G + +VSE  E Y +G N+  QL  G       P+L P       I A  G++ T  ++ 
Sbjct: 363 GDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEA--GQYCTFVIST 420

Query: 569 TGCVYACGDNKSGQCGLGNTTPQ 637
            G V ACG    G+ GLG++  Q
Sbjct: 421 DGSVRACGKGSYGRLGLGDSNNQ 443



 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 359  YRLIVSGCTAGHSVLVSEEGE-AYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAA 535
            Y++    C   H++ VS +G   + FG    G+LG G++  +S P+ +  L G  I   A
Sbjct: 4186 YQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVA 4245

Query: 536  VGRHHTLFVTDTGCVYACGDNK 601
             G   ++ +T  G VY  G ++
Sbjct: 4246 CGTQFSVALTKDGHVYTFGQDR 4267



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           H + +S + E Y +G N+ GQ G G+ T   + P+ V  L G  I   + G  H+L
Sbjct: 676 HCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSL 731


>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
           protein.
          Length = 1024

 Score = 73.7 bits (173), Expect = 9e-13
 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL- 556
           C   HS L++++G  +TFG    GQLG   T     P LV EL G  +   A GR HTL 
Sbjct: 250 CGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLA 309

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV 688
           +V+D G V++ G  K GQ G G T  Q++ P  +K + +  +K+
Sbjct: 310 YVSDLGKVFSFGSGKDGQLGNGGTRDQLM-PLPVKVSSSEELKL 352



 Score = 66.9 bits (156), Expect = 1e-10
 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  +S  G  Y++G+N CGQLG G T ++  P L+  L  + +   A G  H+  +T  
Sbjct: 202 HSTALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGCXCPXXXXXXXCNGNLHSF 748
           G ++  G  K GQ G  N+T   L+P  + +  G  + ++ C            G + SF
Sbjct: 262 GLLFTFGAGKHGQLG-HNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSF 320

Query: 749 G 751
           G
Sbjct: 321 G 321



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 30/90 (33%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S+ GE + +G+N  GQLG G    + + P++V  L G  +   + 
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISA 198

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           G  H+  ++ +G +Y+ G N+ GQ GLG+T
Sbjct: 199 GEAHSTALSMSGNIYSWGKNECGQLGLGHT 228



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +2

Query: 506 LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKY-NGTPIV 682
           L+ K II    G +H+L ++  G ++A G N  GQ G+G   P    P  +++  G P+ 
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLA 194

Query: 683 KVGCXCPXXXXXXXCNGNLHSFG 751
           ++             +GN++S+G
Sbjct: 195 QISAG-EAHSTALSMSGNIYSWG 216


>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
           protein.
          Length = 1024

 Score = 73.7 bits (173), Expect = 9e-13
 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL- 556
           C   HS L++++G  +TFG    GQLG   T     P LV EL G  +   A GR HTL 
Sbjct: 250 CGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLA 309

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV 688
           +V+D G V++ G  K GQ G G T  Q++ P  +K + +  +K+
Sbjct: 310 YVSDLGKVFSFGSGKDGQLGNGGTRDQLM-PLPVKVSSSEELKL 352



 Score = 67.3 bits (157), Expect = 7e-11
 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 1/121 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ +S  G  Y++G+N CGQLG G T ++  P L+  L  + +   A G  H+  +T  
Sbjct: 202 HSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGCXCPXXXXXXXCNGNLHSF 748
           G ++  G  K GQ G  N+T   L+P  + +  G  + ++ C            G + SF
Sbjct: 262 GLLFTFGAGKHGQLG-HNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSF 320

Query: 749 G 751
           G
Sbjct: 321 G 321



 Score = 61.7 bits (143), Expect = 4e-09
 Identities = 30/90 (33%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S+ GE + +G+N  GQLG G    + + P++V  L G  +   + 
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISA 198

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           G  H++ ++ +G +Y+ G N+ GQ GLG+T
Sbjct: 199 GEAHSMALSMSGNIYSWGKNECGQLGLGHT 228



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +2

Query: 506 LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKY-NGTPIV 682
           L+ K II    G +H+L ++  G ++A G N  GQ G+G   P    P  +++  G P+ 
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLA 194

Query: 683 KVGCXCPXXXXXXXCNGNLHSFG 751
           ++             +GN++S+G
Sbjct: 195 QISAG-EAHSMALSMSGNIYSWG 216


>X97668-1|CAA66258.1|  815|Homo sapiens XLRP3 protein.
          Length = 815

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>U57629-1|AAC50481.1|  815|Homo sapiens retinitis pigmentosa GTPase
           regulator protein.
          Length = 815

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>BC031624-1|AAH31624.1|  480|Homo sapiens RPGR protein protein.
          Length = 480

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>AL606748-2|CAI95407.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator protein.
          Length = 815

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>AK223491-1|BAD97211.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator variant protein.
          Length = 815

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>AJ318463-1|CAC86116.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator protein.
          Length = 815

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.4 bits (130), Expect = 1e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GNPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>AJ238395-1|CAB54002.1|  646|Homo sapiens RPGR protein protein.
          Length = 646

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 560 VTDTGCVYACGDNKSGQCGLGNT 628
            T+ G VYA G N  GQ GLG+T
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDT 124



 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 538
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLG 622
           G +HT  +TD G +Y  GD + G+ GLG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLG 330



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 547
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXC 727
            +  +T+ G ++  GDN  GQ GL N +  +  P ++   G P+  + C           
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTI-GKPVSWISCGY-YHSAFVTT 207

Query: 728 NGNLHSFG 751
           +G L+ FG
Sbjct: 208 DGELYVFG 215



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 553
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           + +T+   VY  G  + GQ GLG    +  +P  I+
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 36.3 bits (80), Expect = 0.16
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCP 703
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +K      VK+     
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACGR 96

Query: 704 XXXXXXXCNGNLHSFG 751
                    GN+++ G
Sbjct: 97  NHTLVSTEGGNVYATG 112


>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 71.3 bits (167), Expect = 5e-12
 Identities = 46/118 (38%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 523
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  IK  +   IV+V C
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC 144



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 320



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 350



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 541
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 240


>AY650033-1|AAV66579.1|  979|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 3 protein.
          Length = 979

 Score = 71.3 bits (167), Expect = 5e-12
 Identities = 46/118 (38%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 523
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  IK  +   IV+V C
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC 144



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 320



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 350



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 541
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 240


>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 1 protein.
          Length = 1057

 Score = 71.3 bits (167), Expect = 5e-12
 Identities = 46/118 (38%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 523
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  IK  +   IV+V C
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC 144



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 320



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 350



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 541
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 240


>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 71.3 bits (167), Expect = 5e-12
 Identities = 46/118 (38%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 523
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  IK  +   IV+V C
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC 144



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 320



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 350



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 541
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 240


>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 71.3 bits (167), Expect = 5e-12
 Identities = 46/118 (38%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 523
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 524 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  IK  +   IV+V C
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC 144



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 320



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 350



 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 541
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 240


>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
          Length = 1054

 Score = 70.9 bits (166), Expect = 6e-12
 Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 45  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 102

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           ++D G +++ G    GQ GL  T   +  P  I K N   I++V C
Sbjct: 103 LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 148



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 244 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 303

Query: 533 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 628
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 304 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 336



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 541
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 90  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 149

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
             H L +   G  +  G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 150 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 199



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 31/121 (25%), Positives = 56/121 (46%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 205 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 264

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +   ++     ++  G+ + ++ C           +G +++FG
Sbjct: 265 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 324

Query: 752 C 754
           C
Sbjct: 325 C 325



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 148 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 207

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGT-PIVKVGC 694
            ++ +G V+  G N +GQ GL +   +   P  +K   T  +V + C
Sbjct: 208 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISC 253


>BC038960-1|AAH38960.1|  368|Homo sapiens HERC3 protein protein.
          Length = 368

 Score = 70.9 bits (166), Expect = 6e-12
 Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 41  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 98

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           ++D G +++ G    GQ GL  T   +  P  I K N   I++V C
Sbjct: 99  LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 299

Query: 533 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 628
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 300 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 541
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 86  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
             H L +   G  +  G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 146 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 195



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 31/121 (25%), Positives = 56/121 (46%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 201 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +   ++     ++  G+ + ++ C           +G +++FG
Sbjct: 261 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320

Query: 752 C 754
           C
Sbjct: 321 C 321



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 144 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 203

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGT-PIVKVGC 694
            ++ +G V+  G N +GQ GL +   +   P  +K   T  +V + C
Sbjct: 204 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISC 249


>AC098582-1|AAY41038.1|  382|Homo sapiens unknown protein.
          Length = 382

 Score = 70.9 bits (166), Expect = 6e-12
 Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 41  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 98

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           ++D G +++ G    GQ GL  T   +  P  I K N   I++V C
Sbjct: 99  LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 299

Query: 533 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 628
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 300 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 541
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 86  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
             H L +   G  +  G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 146 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 195



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 31/121 (25%), Positives = 56/121 (46%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 201 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 260

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +   ++     ++  G+ + ++ C           +G +++FG
Sbjct: 261 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320

Query: 752 C 754
           C
Sbjct: 321 C 321



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 144 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 203

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGT-PIVKVGC 694
            ++ +G V+  G N +GQ GL +   +   P  +K   T  +V + C
Sbjct: 204 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISC 249


>BC029052-1|AAH29052.1|  551|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 551

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KY 664
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+   
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 665 NGTPIVKVGC 694
            G  + +V C
Sbjct: 255 QGIRVQRVAC 264



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            G V+A G N SGQ G G+T  Q + P R+
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPI-PRRV 198



 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 545 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXXX 721
            HTL +TD G VYA G N  GQ G GN + Q   PT +      I+++  C         
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEIAACHSTHTSAAK 325

Query: 722 XCNGNLHSFG-CR 757
              G+++ +G CR
Sbjct: 326 TQGGHVYMWGQCR 338



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 40/127 (31%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
 Frame = +2

Query: 335 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 502
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 503 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GT 673
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I  N    
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 674 PIVKVGC 694
            +++V C
Sbjct: 153 QVIEVAC 159


>AY341245-1|AAP88928.1|  551|Homo sapiens chromosome condensation
           1-like protein.
          Length = 551

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KY 664
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+   
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 665 NGTPIVKVGC 694
            G  + +V C
Sbjct: 255 QGIRVQRVAC 264



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            G V+A G N SGQ G G+T  Q + P R+
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPI-PRRV 198



 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 545 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXXX 721
            HTL +TD G VYA G N  GQ G GN + Q   PT +      I+++  C         
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEIAACHSTHTSAAK 325

Query: 722 XCNGNLHSFG-CR 757
              G+++ +G CR
Sbjct: 326 TQGGHVYMWGQCR 338



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 40/127 (31%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
 Frame = +2

Query: 335 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 502
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 503 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GT 673
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I  N    
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 674 PIVKVGC 694
            +++V C
Sbjct: 153 QVIEVAC 159


>AL157813-1|CAH70795.1|  551|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 551

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KY 664
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+   
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 665 NGTPIVKVGC 694
            G  + +V C
Sbjct: 255 QGIRVQRVAC 264



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            G V+A G N SGQ G G+T  Q + P R+
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPI-PRRV 198



 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 545 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXXX 721
            HTL +TD G VYA G N  GQ G GN + Q   PT +      I+++  C         
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEIAACHSTHTSAAK 325

Query: 722 XCNGNLHSFG-CR 757
              G+++ +G CR
Sbjct: 326 TQGGHVYMWGQCR 338



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 40/127 (31%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
 Frame = +2

Query: 335 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 502
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 503 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GT 673
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I  N    
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 674 PIVKVGC 694
            +++V C
Sbjct: 153 QVIEVAC 159


>AF060219-1|AAC79987.1|  551|Homo sapiens RCC1-like G exchanging
           factor RLG protein.
          Length = 551

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KY 664
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+   
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 665 NGTPIVKVGC 694
            G  + +V C
Sbjct: 255 QGIRVQRVAC 264



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            G V+A G N SGQ G G+T  Q + P R+
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPI-PRRV 198



 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 545 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXXX 721
            HTL +TD G VYA G N  GQ G GN + Q   PT +      I+++  C         
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEIAACHSTHTSAAK 325

Query: 722 XCNGNLHSFG-CR 757
              G+++ +G CR
Sbjct: 326 TQGGHVYMWGQCR 338



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 40/127 (31%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
 Frame = +2

Query: 335 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 502
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 503 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GT 673
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I  N    
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 674 PIVKVGC 694
            +++V C
Sbjct: 153 QVIEVAC 159


>AC004460-2|AAC06339.1|  371|Homo sapiens WUGSC:H_DJ1086D14.2
           protein.
          Length = 371

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C A   + +++ G  +T+G+    +LG    V    P++V  L+GK I+H AVG  H L 
Sbjct: 41  CGAQFLLALTKSGVVWTWGKGDYFRLGHRSDVHVRKPQVVEGLRGKKIVHVAVGAQHCLA 100

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKVGC 694
           V D+G VYA GDN  GQ G G TT    KP  ++   G  I+ V C
Sbjct: 101 VMDSGQVYAWGDNDHGQQGNGTTTVN-RKPMLVQGLEGQKIMCVAC 145


>AB209543-1|BAD92780.1|  556|Homo sapiens RCC1-like G exchanging
           factor RLG variant protein.
          Length = 556

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 141 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 200

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KY 664
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+   
Sbjct: 201 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 259

Query: 665 NGTPIVKVGC 694
            G  + +V C
Sbjct: 260 QGIRVQRVAC 269



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 115 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 174

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
            G V+A G N SGQ G G+T  Q + P R+
Sbjct: 175 DGEVFAWGYNNSGQVGSGSTVNQPI-PRRV 203



 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 212 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 271

Query: 545 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXXX 721
            HTL +TD G VYA G N  GQ G GN + Q   PT +      I+++  C         
Sbjct: 272 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEIAACHSTHTSAAK 330

Query: 722 XCNGNLHSFG-CR 757
              G+++ +G CR
Sbjct: 331 TQGGHVYMWGQCR 343



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 40/127 (31%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
 Frame = +2

Query: 335 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 502
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 39  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 98

Query: 503 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GT 673
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I  N    
Sbjct: 99  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 157

Query: 674 PIVKVGC 694
            +++V C
Sbjct: 158 QVIEVAC 164


>AF224249-1|AAO27475.1|  328|Homo sapiens HERC2 protein.
          Length = 328

 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 35/79 (44%), Positives = 48/79 (60%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C A  S+ +++ G  +T+G+    +LG G  V    P++V  L+GK I+H AVG  H L 
Sbjct: 250 CGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLA 309

Query: 560 VTDTGCVYACGDNKSGQCG 616
           VTD+G VYA GDN  GQ G
Sbjct: 310 VTDSGQVYAWGDNDHGQQG 328



 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 2/107 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH--HT 553
           C + HS  ++  GE YT+G    G+LG GD  T+  P++V  L G  +I  A G     T
Sbjct: 144 CGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQT 203

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
           L +TD G V++ GD   G+ G G +    +     + NG  + ++ C
Sbjct: 204 LALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIEC 250



 Score = 41.9 bits (94), Expect = 0.003
 Identities = 27/85 (31%), Positives = 39/85 (45%)
 Frame = +2

Query: 431 FGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQ 610
           +G N   QLG        VP     L   N++  A G      VT  G VYACG+  +G+
Sbjct: 2   WGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGR 61

Query: 611 CGLGNTTPQILKPTRIKYNGTPIVK 685
            GLG ++  +  P +I    + +VK
Sbjct: 62  LGLGISSGTVPIPRQITALSSYVVK 86



 Score = 41.1 bits (92), Expect = 0.006
 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
 Frame = +2

Query: 368 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 547
           +  G     ++ +++EG  +++G    G+LG G +   ++P+ +  L G+ +     G  
Sbjct: 194 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQ 253

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            +L +T +G V+  G     + G G+    + KP  ++   G  IV V
Sbjct: 254 FSLALTKSGVVWTWGKGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHV 300



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 4/75 (5%)
 Frame = +2

Query: 404 VSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV---GRHHTLFVTDT 571
           V+ EG+ Y  G    G+LG G  + T  +P  +  L    +   AV   GRH T    D 
Sbjct: 45  VTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVD- 103

Query: 572 GCVYACGDNKSGQCG 616
           G V+  G+   G+ G
Sbjct: 104 GKVFWWGEGDDGKLG 118


>BC038104-1|AAH38104.1|  355|Homo sapiens RCBTB1 protein protein.
          Length = 355

 Score = 69.3 bits (162), Expect = 2e-11
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 2/117 (1%)
 Frame = +2

Query: 314 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 490
           T+  + T    T+   + +V   C + HS+ ++ +GE + +G N CGQ+G G T  +  P
Sbjct: 112 TNQGIATVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTP 171

Query: 491 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             V   L  K ++  A G+  ++ V D G VY  G N +GQ GLGN   Q L P R+
Sbjct: 172 RKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRV 227



 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXX 718
             HTL +TD G +YA G N  GQ G GN    +L P  I      +V++  C        
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEIAACHSAHTSAA 300

Query: 719 XXCNGNLHSFG-CR 757
               G+++ +G CR
Sbjct: 301 KTQGGHVYMWGQCR 314



 Score = 54.8 bits (126), Expect = 4e-07
 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 542 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI 640
              H L  T+ G VYA G N   Q G G T   I
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGI 116


>AL139321-5|CAH71047.1|  531|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 531

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 538
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRV 227



 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXX 718
             HTL +TD G +YA G N  GQ G GN    +L P  I      +V++  C        
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEIAACHSAHTSAA 300

Query: 719 XXCNGNLHSFG-CR 757
               G+++ +G CR
Sbjct: 301 KTQGGHVYMWGQCR 314



 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK--VGCXCPXXXXXXXC-NGNL 739
            G V+A G N  GQ G G+T  Q   PT  K      +K  VG  C          NG +
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ---PTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEV 202

Query: 740 HSFG 751
           + +G
Sbjct: 203 YGWG 206



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 39/111 (35%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
 Frame = +2

Query: 371 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-H 547
           V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G   
Sbjct: 26  VFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGP 85

Query: 548 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GTPIVKVGC 694
           H L  T+ G VYA G N   Q G G TT Q + P ++  N     +V+V C
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVAC 135


>AK096654-1|BAC04833.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39335 fis, clone OCBBF2017398, moderately
           similar to Homo sapiens RCC1-like G exchanging factor
           RLG mRNA. ).
          Length = 531

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 538
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRV 227



 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXX 718
             HTL +TD G +YA G N  GQ G GN    +L P  I      +V++  C        
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEIAACHSAHTSAA 300

Query: 719 XXCNGNLHSFG-CR 757
               G+++ +G CR
Sbjct: 301 KTQGGHVYMWGQCR 314



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 542 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GTPIVKVGC 694
              H L  T+ G VYA G N   Q G G TT Q + P ++  N     +V+V C
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVAC 135



 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK--VGCXCPXXXXXXXC-NGNL 739
            G V+A G N  GQ G G+T  Q   PT  K      +K  VG  C          NG +
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ---PTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEV 202

Query: 740 HSFG 751
           + +G
Sbjct: 203 YGWG 206


>AJ319660-1|CAC40027.1|  531|Homo sapiens guanine nucleotide
           exchange factor protein.
          Length = 531

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 538
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRV 227



 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXX 718
             HTL +TD G +YA G N  GQ G GN    +L P  I      +V++  C        
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEIAACHSAHTSAA 300

Query: 719 XXCNGNLHSFG-CR 757
               G+++ +G CR
Sbjct: 301 KTQGGHVYMWGQCR 314



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 542 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GTPIVKVGC 694
              H L  T+ G VYA G N   Q G G TT Q + P ++  N     +V+V C
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVAC 135



 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK--VGCXCPXXXXXXXC-NGNL 739
            G V+A G N  GQ G G+T  Q   PT  K      +K  VG  C          NG +
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ---PTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEV 202

Query: 740 HSFG 751
           + +G
Sbjct: 203 YGWG 206


>AF334406-1|AAK38372.1|  531|Homo sapiens CLLL7 protein protein.
          Length = 531

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 538
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRV 227



 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 542 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKV-GCXCPXXXXX 718
             HTL +TD G +YA G N  GQ G GN    +L P  I      +V++  C        
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEIAACHSAHTSAA 300

Query: 719 XXCNGNLHSFG-CR 757
               G+++ +G CR
Sbjct: 301 KTQGGHVYMWGQCR 314



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 541
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 542 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYN--GTPIVKVGC 694
              H L  T+ G VYA G N   Q G G TT Q + P ++  N     +V+V C
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVAC 135



 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 568
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 569 TGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK--VGCXCPXXXXXXXC-NGNL 739
            G V+A G N  GQ G G+T  Q   PT  K      +K  VG  C          NG +
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ---PTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEV 202

Query: 740 HSFG 751
           + +G
Sbjct: 203 YGWG 206


>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
           tyrosine kinase-beta protein.
          Length = 1196

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 300 T-REAVYTMGLN-GGQLG 315



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
           tyrosine kinase-alpha protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 300 T-REAVYTMGLN-GGQLG 315



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
           agammaglobulinemia tyrosine kinase protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 300 T-REAVYTMGLN-GGQLG 315



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
           agammaglobulinemia tyrosine kinase protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 300 T-REAVYTMGLN-GGQLG 315



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
          Length = 1187

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 184 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 243

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 244 GCVYTFGLNIFHQLGI 259



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 236 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 295

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 296 T-REAVYTMGLN-GGQLG 311



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 139 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 198

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 199 HGPGGRLGHGD 209


>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
          Length = 1379

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 214 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 273

Query: 572 GCVYACGDNKSGQCGL 619
           GCVY  G N   Q G+
Sbjct: 274 GCVYTFGLNIFHQLGI 289



 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 562
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 266 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 325

Query: 563 TDTGCVYACGDNKSGQCG 616
           T    VY  G N  GQ G
Sbjct: 326 T-REAVYTMGLN-GGQLG 341



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 419 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 169 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 228

Query: 593 DNKSGQCGLGN 625
               G+ G G+
Sbjct: 229 HGPGGRLGHGD 239


>AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 51  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 110

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 111 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 170



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 90  RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 149

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 150 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 200



 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
 Frame = +2

Query: 401 LVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGC 577
           +     E + +G+N  GQLG G D   ++ P+L+  L G   +  A G  H+  +T +G 
Sbjct: 1   MAESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60

Query: 578 VYACGDNKSGQCGLGNT----TPQILKPTR 655
           ++  G NK GQ GL +      P +LK  R
Sbjct: 61  IFGWGRNKFGQLGLNDENDRYVPNLLKSLR 90


>AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 51  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 110

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 111 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 170



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 90  RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 149

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 150 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 200



 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
 Frame = +2

Query: 401 LVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGC 577
           +     E + +G+N  GQLG G D   ++ P+L+  L G   +  A G  H+  +T +G 
Sbjct: 1   MAESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60

Query: 578 VYACGDNKSGQCGLGNT----TPQILKPTR 655
           ++  G NK GQ GL +      P +LK  R
Sbjct: 61  IFGWGRNKFGQLGLNDENDRYVPNLLKSLR 90


>AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.
          Length = 953

 Score = 67.7 bits (158), Expect = 6e-11
 Identities = 35/120 (29%), Positives = 58/120 (48%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 97  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 156

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLHSFG 751
           G V+  G    GQ G  +T+ +I      +  G+ + ++ C           +G ++SFG
Sbjct: 157 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFG 216



 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 532
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 136 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 195

Query: 533 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRIKYNG 670
           A GR HT  FV  +G +Y+ G   +GQ G G+T    +P  +K     YNG
Sbjct: 196 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNG 246



 Score = 59.7 bits (138), Expect = 1e-08
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 34  QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 93

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTR 655
           G  H+  +T +G ++  G NK GQ GL +      P +LK  R
Sbjct: 94  GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 136



 Score = 37.1 bits (82), Expect = 0.091
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
 Frame = +2

Query: 497 VPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 646
           +  L    I+  A G +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 27  IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 81


>BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.
          Length = 651

 Score = 64.5 bits (150), Expect = 5e-10
 Identities = 35/93 (37%), Positives = 49/93 (52%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C    SV ++++G  YTFG++    L  G     + P+ +P L G  I   AVG  HTL 
Sbjct: 36  CGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLA 95

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           +   G VYA G N  GQ GLG+T   + +PT +
Sbjct: 96  LASNGDVYAWGSNSEGQLGLGHTN-HVREPTLV 127



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
 Frame = +2

Query: 386 AGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-HHTLFV 562
           A H++ ++  G+ Y +G N+ GQLG G T     P LV  L+GKN+   + GR H   + 
Sbjct: 90  AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 149

Query: 563 TDTGCVYACGDNKSGQCGLGNTTP 634
                  A G +   Q GL +T P
Sbjct: 150 APPVPPRAPGVSVPLQLGLPDTVP 173


>BC112101-1|AAI12102.1|  979|Homo sapiens NIMA related kinase 9
           protein.
          Length = 979

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 416 QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 476 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 506



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 641 NLLGGPLGGKQVIRVSC 657


>BC093881-1|AAH93881.1|  979|Homo sapiens NIMA (never in mitosis
           gene a)- related kinase 9 protein.
          Length = 979

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 416 QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 476 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 506



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 641 NLLGGPLGGKQVIRVSC 657


>AY080896-1|AAL87410.1|  979|Homo sapiens NIMA-family kinase NERCC1
           protein.
          Length = 979

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 416 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 476 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 506



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 641 NLLGGPLGGKQVIRVSC 657


>AY048580-1|AAL05428.1|  979|Homo sapiens NIMA-related kinase Nek8
           protein.
          Length = 979

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 416 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 476 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 506



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 641 NLLGGPLGGKQVIRVSC 657


>AC007055-4|AAD31939.1|  414|Homo sapiens protein ( Homo sapiens
           chromosome 14 clone BAC 201F1 map 14q24.3, complete
           sequence. ).
          Length = 414

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 26  KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 85

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 86  QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 145

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 146 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 176



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 268 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 325

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 326 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 357



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 191 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 250

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 251 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 310

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 311 NLLGGPLGGKQVIRVSC 327


>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
          Length = 1011

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 47/152 (30%), Positives = 74/152 (48%), Gaps = 14/152 (9%)
 Frame = +2

Query: 341 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 484
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 388 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 447

Query: 485 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIK 661
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++ 
Sbjct: 448 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 507

Query: 662 -YNGTPIVKVGCXCPXXXXXXXCNGNLHSFGC 754
            +   P+ +V C           N  ++S+GC
Sbjct: 508 FFLSNPVEQVSCG-DNHVVVLTRNKEVYSWGC 538



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 356 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 532
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 630 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 687

Query: 533 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 628
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 688 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 719



 Score = 33.1 bits (72), Expect = 1.5
 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
 Frame = +2

Query: 329 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 481
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 553 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 612

Query: 482 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 643
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 613 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 672

Query: 644 KPTRIKYNGTPIVKVGC 694
                   G  +++V C
Sbjct: 673 NLLGGPLGGKQVIRVSC 689


>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
           protein.
          Length = 1022

 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 556
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            ++    V++ G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 186



 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLH 742
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C            G + 
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTTGQVV 310

Query: 743 SFG 751
           SFG
Sbjct: 311 SFG 313



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 243



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 545 HHTL-FVTDTGCVYACGDNKS 604
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           G V+A G    GQ G+G        P +I   N   I++V C
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           G  ++ AA G  H+L +     V +CGDN  GQ G
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLG 56


>AY653203-1|AAV66897.1|  322|Homo sapiens truncated HERC6 protein.
          Length = 322

 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 556
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            ++    V++ G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 186



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 243



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDC 294



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           G V+A G    GQ G+G        P +I   N   I++V C
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/50 (32%), Positives = 30/50 (60%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG 514
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG 287



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           G  ++ AA G  H+L +     V +CGDN  GQ G
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLG 56


>AY653202-1|AAV66896.1|  364|Homo sapiens truncated HERC6 protein.
          Length = 364

 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 556
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            ++    V++ G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 186



 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLH 742
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C            G + 
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTTGQVV 310

Query: 743 SFG 751
           SFG
Sbjct: 311 SFG 313



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 243



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 545 HHTL-FVTDTGCVYACGDNKS 604
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           G V+A G    GQ G+G        P +I   N   I++V C
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           G  ++ AA G  H+L +     V +CGDN  GQ G
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLG 56


>AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant
           protein.
          Length = 986

 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 556
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            ++    V++ G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 186



 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLH 742
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C            G + 
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTTGQVV 310

Query: 743 SFG 751
           SFG
Sbjct: 311 SFG 313



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 243



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 545 HHTL-FVTDTGCVYACGDNKS 604
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           G V+A G    GQ G+G        P +I   N   I++V C
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           G  ++ AA G  H+L +     V +CGDN  GQ G
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLG 56


>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
          Length = 1022

 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 556
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 557 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
            ++    V++ G N  GQ GLG   P    P R++   G P+ +V
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQV 186



 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGNLH 742
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C            G + 
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTTGQVV 310

Query: 743 SFG 751
           SFG
Sbjct: 311 SFG 313



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 243



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 545 HHTL-FVTDTGCVYACGDNKS 604
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
           G V+A G    GQ G+G        P +I   N   I++V C
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSC 135



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           G  ++ AA G  H+L +     V +CGDN  GQ G
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLG 56


>AF225407-1|AAO27483.1|  409|Homo sapiens HERC2 protein.
          Length = 409

 Score = 60.5 bits (140), Expect = 9e-09
 Identities = 37/106 (34%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C +  SV +++ G  YT+G+    +LG G       P  V  L+GK +I  A G  H + 
Sbjct: 108 CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVC 167

Query: 560 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI-KYNGTPIVKVGC 694
            T+ G VY  GDN  GQ G G TT  I +P  +    G  + +V C
Sbjct: 168 CTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLVAALQGKKVNRVAC 212



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHTLFVT 565
           HS  V+  G+ YT+G+   G+LG  D+  +  P+LV  L+G  ++  A G     TL +T
Sbjct: 6   HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 65

Query: 566 DTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
           D   V++ GD   G+ G G +    +        G  +VKV C
Sbjct: 66  DDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVEC 108



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 26/55 (47%), Positives = 31/55 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 556
           H V  +E+GE YT+G N  GQLG G T     P LV  L+GK +   A G  HTL
Sbjct: 164 HCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 218


>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 350  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 529
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 530  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 293 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 466
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 467 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 350  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 529
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 530  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 293 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 466
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 467 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 350  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 529
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 530  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 293 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 466
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 467 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
            protein.
          Length = 4641

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 350  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 529
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 530  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 616
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/84 (33%), Positives = 46/84 (54%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 544
           ++ + C  G S ++S++GE Y FG++A     + D+ +     LV +LKG  +   A+G+
Sbjct: 602 VVYTACNNGSSSVISKDGELYMFGKDAI----YSDSSS-----LVTDLKGHFVTQVAMGK 652

Query: 545 HHTLFVTDTGCVYACGDNKSGQCG 616
            HT  +   G V+  G N  GQCG
Sbjct: 653 AHTCVLMKNGEVWTFGVNNKGQCG 676


>BC029174-1|AAH29174.1|  812|Homo sapiens ALS2 protein protein.
          Length = 812

 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAK 605



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 31/78 (39%), Positives = 44/78 (56%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y CG+N +GQC + N
Sbjct: 110 GVAYMCGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
          Length = 1657

 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAK 605



 Score = 54.0 bits (124), Expect = 7e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLLWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
          Length = 1598

 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 460 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 519

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 520 QVYSWGSNTFGQLGHSDFPTTVPRLAK 546



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 26/70 (37%), Positives = 36/70 (51%)
 Frame = +2

Query: 416 GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGD 595
           GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD G  Y  G+
Sbjct: 1   GEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGE 58

Query: 596 NKSGQCGLGN 625
           N +GQC + N
Sbjct: 59  NSAGQCAVAN 68



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 511 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 569


>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
          Length = 1657

 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAK 605



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
          Length = 1658

 Score = 58.4 bits (135), Expect = 3e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 520 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 579

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 580 QVYSWGSNTFGQLGHSDFPTTVPRLAK 606



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 53  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 110

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 111 GVAYMWGENSAGQCAVAN 128



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 571 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 629



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 33  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 67


>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
          Length = 1237

 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 395 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 574
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRIEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 575 CVYACGDNKSGQCG---LGNTTPQILK 646
            VY+ G N  GQ G      T P++ K
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAK 605



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>BC065375-1|AAH65375.1|  458|Homo sapiens secretion regulating
           guanine nucleotide exchange factor protein.
          Length = 458

 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 526
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 527 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIV 682
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I+ +   +V
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVV 156



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +2

Query: 425 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 601
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 602 SGQCGLGNTTP-QILKPTRIKYNGTPIVKVGC 694
            GQ GLG+T       P +  + G PI +V C
Sbjct: 78  DGQLGLGHTEDIPYFTPCKSLF-GCPIQQVAC 108



 Score = 35.9 bits (79), Expect = 0.21
 Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 550
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 551 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           +  +TD G VY  G NK GQ  L N    +  P +I+
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKIE 258


>AJ243951-1|CAB60833.1|  288|Homo sapiens deafness locus associated
           putative guanine nucleotide exchange factor protein.
          Length = 288

 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 526
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 527 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIV 682
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I+ +   +V
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVV 156



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +2

Query: 425 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 601
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 602 SGQCGLGNTTP-QILKPTRIKYNGTPIVKVGC 694
            GQ GLG+T       P +  + G PI +V C
Sbjct: 78  DGQLGLGHTEDIPYFTPCKSLF-GCPIQQVAC 108



 Score = 35.9 bits (79), Expect = 0.21
 Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 550
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 551 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           +  +TD G VY  G NK GQ  L N    +  P +I+
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKIE 258


>AJ243950-1|CAB60832.1|  458|Homo sapiens deafness locus associated
           putative guanine nucleotide exchange factor protein.
          Length = 458

 Score = 57.2 bits (132), Expect = 8e-08
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
 Frame = +2

Query: 353 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 526
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 527 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIV 682
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I+ +   +V
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVV 156



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +2

Query: 425 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 601
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 602 SGQCGLGNTTP-QILKPTRIKYNGTPIVKVGC 694
            GQ GLG+T       P +  + G PI +V C
Sbjct: 78  DGQLGLGHTEDIPYFTPCKSLF-GCPIQQVAC 108



 Score = 35.9 bits (79), Expect = 0.21
 Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 550
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 551 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK 661
           +  +TD G VY  G NK GQ  L N    +  P +I+
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKIE 258


>BC113705-1|AAI13706.1|  692|Homo sapiens NIMA (never in mitosis
           gene a)- related kinase 8 protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 359 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 538
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL 619
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 560 VTDTGCVYACGDNKSGQCGLG 622
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 42.7 bits (96), Expect = 0.002
 Identities = 26/89 (29%), Positives = 39/89 (43%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             VY+ G    G+ G  +    + +P ++
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQL 660



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT ++   G  +V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 689 GC 694
            C
Sbjct: 449 AC 450


>BC112240-1|AAI12241.1|  692|Homo sapiens NIMA-related kinase 8
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 359 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 538
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL 619
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 560 VTDTGCVYACGDNKSGQCGLG 622
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 42.7 bits (96), Expect = 0.002
 Identities = 26/89 (29%), Positives = 39/89 (43%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             VY+ G    G+ G  +    + +P ++
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQL 660



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT ++   G  +V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 689 GC 694
            C
Sbjct: 449 AC 450


>AY267371-1|AAP04006.1|  692|Homo sapiens NIMA-family kinase NEK8
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 359 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 538
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL 619
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 560 VTDTGCVYACGDNKSGQCGLG 622
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 42.7 bits (96), Expect = 0.002
 Identities = 26/89 (29%), Positives = 39/89 (43%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             VY+ G    G+ G  +    + +P ++
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQL 660



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT ++   G  +V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 689 GC 694
            C
Sbjct: 449 AC 450


>AY242354-1|AAO88243.1|  692|Homo sapiens NIMA-related kinase 12a
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 359 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 538
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL 619
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 559
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 560 VTDTGCVYACGDNKSGQCGLG 622
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 42.7 bits (96), Expect = 0.002
 Identities = 26/89 (29%), Positives = 39/89 (43%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 572 GCVYACGDNKSGQCGLGNTTPQILKPTRI 658
             VY+ G    G+ G  +    + +P ++
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQL 660



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +2

Query: 512 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIK-YNGTPIVKV 688
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT ++   G  +V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 689 GC 694
            C
Sbjct: 449 AC 450


>AK023024-1|BAB14362.1|  396|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
           X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
          Length = 396

 Score = 54.0 bits (124), Expect = 7e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLLWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AK092403-1|BAC03879.1|  184|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35084 fis, clone PLACE6005482. ).
          Length = 184

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 4/115 (3%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 538
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 7   KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 66

Query: 539 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRI-KYNGTPIVKVGC 694
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +       +V + C
Sbjct: 67  GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 121



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 562
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 70  HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 129

Query: 563 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGC 694
           T  G V+  GDN+SGQ G  + TP+   P  ++     + ++ C
Sbjct: 130 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDC 172



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/50 (32%), Positives = 30/50 (60%)
 Frame = +2

Query: 365 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG 514
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G
Sbjct: 116 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG 165


>AB053306-1|BAB69015.1|  396|Homo sapiens ALS2 protein.
          Length = 396

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 571
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 572 GCVYACGDNKSGQCGLGN 625
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 488 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>X12654-1|CAA31182.1|  421|Homo sapiens protein ( Human mRNA for
           cell cycle gene RCC1. ).
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>X06130-1|CAA29496.1|  421|Homo sapiens protein ( Human mRNA for
           cell cycle gene RCC1. ).
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>D00591-1|BAA00469.1|  421|Homo sapiens RCC1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>CR407693-1|CAG28621.1|  421|Homo sapiens CHC1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>BC069198-1|AAH69198.1|  452|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 452

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 109 HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 165

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 166 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 223

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 224 LYTLGC 229



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 278 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 337

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 338 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 372



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 336 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 393

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 394 DGRVFAWGMGTNYQLGTG 411



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 63  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 120

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 121 SFGCNDEGALG 131


>BC036903-1|AAH36903.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>BC010067-1|AAH10067.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>BC007300-1|AAH07300.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>AL513497-2|CAI22287.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>AF498924-1|AAM21072.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 562
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 563 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRIKYNGTPIVKVGCXCPXXXXXXXCNGN 736
           TD G V+  G   + +G  GL     + + P +++ +  P+VKV             +G+
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASG-NDHLVMLTADGD 192

Query: 737 LHSFGC 754
           L++ GC
Sbjct: 193 LYTLGC 198



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 380 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 553
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 554 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 658
           + +   G  Y+ G  + G+ GLG    +   PT I
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLI 341



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 392 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 568
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 569 TGCVYACGDNKSGQCGLG 622
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 407 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 583
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 584 ACGDNKSGQCG 616
           + G N  G  G
Sbjct: 90  SFGCNDEGALG 100


>BC040695-1|AAH40695.1|  358|Homo sapiens WBSCR16 protein protein.
          Length = 358

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 529
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 530 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 625
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = +2

Query: 338 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 514
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 515 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
            N+I  A      L V+  G ++  G+++  Q      + Q+  P  + ++G   V+
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVR 339


>BC032712-1|AAH32712.1|  454|Homo sapiens WBSCR16 protein protein.
          Length = 454

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 529
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 530 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 625
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = +2

Query: 338 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 514
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 515 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
            N+I  A      L V+  G ++  G+++  Q      + Q+  P  + ++G   V+
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVR 339


>BC019008-1|AAH19008.1|  464|Homo sapiens Williams-Beuren syndrome
           chromosome region 16 protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 529
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 530 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 625
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = +2

Query: 338 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 514
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 515 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
            N+I  A      L V+  G ++  G+++  Q      + Q+  P  + ++G   V+
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVR 339


>BC007823-1|AAH07823.1|  464|Homo sapiens Williams-Beuren syndrome
           chromosome region 16 protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 529
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 530 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 625
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = +2

Query: 338 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 514
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 515 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
            N+I  A      L V+  G ++  G+++  Q      + Q+  P  + ++G   V+
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVR 339


>AF410455-1|AAM62304.1|  464|Homo sapiens RCC1-like G exchanging
           factor-like protein protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 362 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 529
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 530 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 625
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = +2

Query: 338 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 514
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 515 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRIKYNGTPIVK 685
            N+I  A      L V+  G ++  G+++  Q      + Q+  P  + ++G   V+
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVR 339


>BC113826-1|AAI13827.1|  244|Homo sapiens RCCD1 protein protein.
          Length = 244

 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/69 (37%), Positives = 37/69 (53%)
 Frame = +2

Query: 413 EGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 592
           E E + F R+  GQLG G       P L+  L+G  +   A G  H++ V++TG +Y  G
Sbjct: 45  ELELHRF-RDPHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWG 103

Query: 593 DNKSGQCGL 619
            N+SGQ  L
Sbjct: 104 WNESGQLAL 112



 Score = 36.7 bits (81), Expect = 0.12
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +2

Query: 368 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 538
           + + C + H+ +V+  GE YT+G    GQLG  DT +   P  V     K +   AV
Sbjct: 171 VKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAV 227



 Score = 32.7 bits (71), Expect = 2.0
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 10/54 (18%)
 Frame = +2

Query: 365 LIVSGCTAG--HSVLVSEEGEAYTFGRNACGQLGF--------GDTVTRSVPEL 496
           L+++   AG  HSV VSE G+ Y +G N  GQL          G+TV R   EL
Sbjct: 78  LVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATEL 131


>AY650032-1|AAV66578.1|  117|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 2 protein.
          Length = 117

 Score = 44.0 bits (99), Expect = 8e-04
 Identities = 29/80 (36%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
 Frame = +2

Query: 431 FGRNACGQLGFGDTVTRSV--PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 604
           +G  + GQLG G      V  P        K +     G  HT+FV D G VY CG N  
Sbjct: 4   WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63

Query: 605 GQCG--LGNTTPQILKPTRI 658
           GQ G       P+ILK  +I
Sbjct: 64  GQLGHEKSRKKPEILKVCQI 83



 Score = 34.7 bits (76), Expect = 0.48
 Identities = 20/52 (38%), Positives = 29/52 (55%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELV 499
           F ++R R +  GC   H+V V ++G  YT G N  GQL  G   +R  PE++
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQL--GHEKSRKKPEIL 78


>AY650034-1|AAV66580.1|  110|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 4 protein.
          Length = 110

 Score = 41.1 bits (92), Expect = 0.006
 Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
 Frame = +2

Query: 431 FGRNACGQLGFGDTVTRSV--PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 604
           +G  + GQLG G      V  P        K +     G  HT+FV D G VY CG N  
Sbjct: 4   WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63

Query: 605 GQCG 616
           GQ G
Sbjct: 64  GQLG 67



 Score = 33.9 bits (74), Expect = 0.85
 Identities = 17/39 (43%), Positives = 23/39 (58%)
 Frame = +2

Query: 344 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG 460
           F ++R R +  GC   H+V V ++G  YT G N  GQLG
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLG 67


>AF225404-1|AAO27482.1|  259|Homo sapiens HERC2 protein.
          Length = 259

 Score = 35.1 bits (77), Expect = 0.37
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
 Frame = +2

Query: 416 GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF-VTDTGCVYACG 592
           G  Y +G N  GQLG  +     VP     L     +   +G   TLF VT  G +YA G
Sbjct: 127 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQ-LIGGEQTLFAVTADGKLYATG 185

Query: 593 DNKSGQCGLGNT----TPQILK 646
               G+ G+G T    TP +L+
Sbjct: 186 YGAGGRLGIGGTESVSTPTLLE 207


>BC067293-1|AAH67293.1|  580|Homo sapiens F-box protein 24 protein.
          Length = 580

 Score = 31.9 bits (69), Expect = 3.4
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = +2

Query: 380 CTAG--HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHT 553
           C  G  H  LV E G  +  G N  GQLG GD + R  P  V  L  +  I    G +H+
Sbjct: 362 CALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHS 419

Query: 554 LFVTDT 571
           L ++ +
Sbjct: 420 LVLSQS 425


>AC069281-1|AAP21863.1|  580|Homo sapiens unknown protein.
          Length = 580

 Score = 31.9 bits (69), Expect = 3.4
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = +2

Query: 380 CTAG--HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHT 553
           C  G  H  LV E G  +  G N  GQLG GD + R  P  V  L  +  I    G +H+
Sbjct: 362 CALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHS 419

Query: 554 LFVTDT 571
           L ++ +
Sbjct: 420 LVLSQS 425


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 123,968,367
Number of Sequences: 237096
Number of extensions: 2902097
Number of successful extensions: 7413
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 6364
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7187
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12158972418
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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