SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fdpeP01_F_I15
         (886 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC142946-1|AAI42947.1|  457|Homo sapiens RCC2 protein protein.        126   1e-28
BC053908-1|AAH53908.1|  522|Homo sapiens RCC2 protein protein.        126   1e-28
BC042141-1|AAH42141.1|  522|Homo sapiens regulator of chromosome...   126   1e-28
AJ421269-1|CAD13148.1|  522|Homo sapiens RCC1-like protein protein.   126   1e-28
AB040903-1|BAA95994.1|  564|Homo sapiens KIAA1470 protein protein.    126   1e-28
AL359612-1|CAB94882.1|  333|Homo sapiens hypothetical protein pr...   116   2e-25
BC004933-1|AAH04933.1|  351|Homo sapiens RCC2 protein protein.         92   2e-18
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.                84   6e-16
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.                   80   1e-14
X97668-1|CAA66258.1|  815|Homo sapiens XLRP3 protein.                  75   3e-13
U57629-1|AAC50481.1|  815|Homo sapiens retinitis pigmentosa GTPa...    75   3e-13
BC031624-1|AAH31624.1|  480|Homo sapiens RPGR protein protein.         75   3e-13
AL606748-2|CAI95407.1|  815|Homo sapiens retinitis pigmentosa GT...    75   3e-13
AK223491-1|BAD97211.1|  815|Homo sapiens retinitis pigmentosa GT...    75   3e-13
AJ318463-1|CAC86116.1|  815|Homo sapiens retinitis pigmentosa GT...    75   3e-13
AJ238395-1|CAB54002.1|  646|Homo sapiens RPGR protein protein.         75   3e-13
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas...    74   6e-13
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei...    74   6e-13
AC004460-2|AAC06339.1|  371|Homo sapiens WUGSC:H_DJ1086D14.2 pro...    74   8e-13
BC029052-1|AAH29052.1|  551|Homo sapiens regulator of chromosome...    73   2e-12
AY341245-1|AAP88928.1|  551|Homo sapiens chromosome condensation...    73   2e-12
AL157813-1|CAH70795.1|  551|Homo sapiens regulator of chromosome...    73   2e-12
AF060219-1|AAC79987.1|  551|Homo sapiens RCC1-like G exchanging ...    73   2e-12
AB209543-1|BAD92780.1|  556|Homo sapiens RCC1-like G exchanging ...    73   2e-12
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p...    72   2e-12
AY650033-1|AAV66579.1|  979|Homo sapiens HECT and RCC1 containin...    72   2e-12
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin...    72   2e-12
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p...    72   2e-12
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p...    72   2e-12
AF224249-1|AAO27475.1|  328|Homo sapiens HERC2 protein.                71   4e-12
BC038104-1|AAH38104.1|  355|Homo sapiens RCBTB1 protein protein.       71   6e-12
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.               71   7e-12
BC038960-1|AAH38960.1|  368|Homo sapiens HERC3 protein protein.        71   7e-12
AL139321-5|CAH71047.1|  531|Homo sapiens regulator of chromosome...    71   7e-12
AK096654-1|BAC04833.1|  531|Homo sapiens protein ( Homo sapiens ...    71   7e-12
AJ319660-1|CAC40027.1|  531|Homo sapiens guanine nucleotide exch...    71   7e-12
AF334406-1|AAK38372.1|  531|Homo sapiens CLLL7 protein protein.        71   7e-12
AC098582-1|AAY41038.1|  382|Homo sapiens unknown protein.              71   7e-12
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t...    68   4e-11
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t...    68   4e-11
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga...    68   4e-11
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga...    68   4e-11
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.          68   4e-11
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.     68   4e-11
BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.        67   7e-11
AF225407-1|AAO27483.1|  409|Homo sapiens HERC2 protein.                64   5e-10
AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4 p...    62   2e-09
AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4 p...    62   2e-09
AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.     62   2e-09
BC112101-1|AAI12102.1|  979|Homo sapiens NIMA related kinase 9 p...    62   3e-09
BC093881-1|AAH93881.1|  979|Homo sapiens NIMA (never in mitosis ...    62   3e-09
AY080896-1|AAL87410.1|  979|Homo sapiens NIMA-family kinase NERC...    62   3e-09
AY048580-1|AAL05428.1|  979|Homo sapiens NIMA-related kinase Nek...    62   3e-09
AC007055-4|AAD31939.1|  414|Homo sapiens protein ( Homo sapiens ...    62   3e-09
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.     62   3e-09
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p...    60   8e-09
AY653203-1|AAV66897.1|  322|Homo sapiens truncated HERC6 protein.      60   8e-09
AY653202-1|AAV66896.1|  364|Homo sapiens truncated HERC6 protein.      60   8e-09
AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant pr...    60   8e-09
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.                60   8e-09
BC029174-1|AAH29174.1|  812|Homo sapiens ALS2 protein protein.         60   1e-08
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.           60   1e-08
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.                60   1e-08
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with...    60   1e-08
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.              60   1e-08
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.                 60   1e-08
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.     60   1e-08
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.         59   2e-08
BC065375-1|AAH65375.1|  458|Homo sapiens secretion regulating gu...    59   2e-08
AJ243951-1|CAB60833.1|  288|Homo sapiens deafness locus associat...    59   2e-08
AJ243950-1|CAB60832.1|  458|Homo sapiens deafness locus associat...    59   2e-08
AK092403-1|BAC03879.1|  184|Homo sapiens protein ( Homo sapiens ...    57   1e-07
BC113705-1|AAI13706.1|  692|Homo sapiens NIMA (never in mitosis ...    56   2e-07
BC112240-1|AAI12241.1|  692|Homo sapiens NIMA-related kinase 8 p...    56   2e-07
AY267371-1|AAP04006.1|  692|Homo sapiens NIMA-family kinase NEK8...    56   2e-07
AY242354-1|AAO88243.1|  692|Homo sapiens NIMA-related kinase 12a...    56   2e-07
AK023024-1|BAB14362.1|  396|Homo sapiens protein ( Homo sapiens ...    54   7e-07
AB053306-1|BAB69015.1|  396|Homo sapiens ALS2 protein.                 53   1e-06
BC040695-1|AAH40695.1|  358|Homo sapiens WBSCR16 protein protein.      52   3e-06
BC032712-1|AAH32712.1|  454|Homo sapiens WBSCR16 protein protein.      52   3e-06
BC019008-1|AAH19008.1|  464|Homo sapiens Williams-Beuren syndrom...    52   3e-06
BC007823-1|AAH07823.1|  464|Homo sapiens Williams-Beuren syndrom...    52   3e-06
AF410455-1|AAM62304.1|  464|Homo sapiens RCC1-like G exchanging ...    52   3e-06
X12654-1|CAA31182.1|  421|Homo sapiens protein ( Human mRNA for ...    51   5e-06
X06130-1|CAA29496.1|  421|Homo sapiens protein ( Human mRNA for ...    51   5e-06
D00591-1|BAA00469.1|  421|Homo sapiens RCC1 protein.                   51   5e-06
CR407693-1|CAG28621.1|  421|Homo sapiens CHC1 protein.                 51   5e-06
BC069198-1|AAH69198.1|  452|Homo sapiens regulator of chromosome...    51   5e-06
BC036903-1|AAH36903.1|  421|Homo sapiens regulator of chromosome...    51   5e-06
BC010067-1|AAH10067.1|  421|Homo sapiens regulator of chromosome...    51   5e-06
BC007300-1|AAH07300.1|  421|Homo sapiens regulator of chromosome...    51   5e-06
AL513497-2|CAI22287.1|  421|Homo sapiens regulator of chromosome...    51   5e-06
AF498924-1|AAM21072.1|  421|Homo sapiens regulator of chromosome...    51   5e-06
AY650032-1|AAV66578.1|  117|Homo sapiens HECT and RCC1 containin...    45   4e-04
BC113826-1|AAI13827.1|  244|Homo sapiens RCCD1 protein protein.        44   6e-04
AY650034-1|AAV66580.1|  110|Homo sapiens HECT and RCC1 containin...    41   0.005
AF225404-1|AAO27482.1|  259|Homo sapiens HERC2 protein.                41   0.005
BC067293-1|AAH67293.1|  580|Homo sapiens F-box protein 24 protein.     32   3.2  
AC069281-1|AAP21863.1|  580|Homo sapiens unknown protein.              32   3.2  
BC103891-1|AAI03892.2|  428|Homo sapiens POM121L1 protein protein.     30   9.7  
AL162741-4|CAI23246.1|  255|Homo sapiens tumor necrosis factor r...    30   9.7  
AF241229-1|AAF63506.1|  255|Homo sapiens GITR-D protein.               30   9.7  

>BC142946-1|AAI42947.1|  457|Homo sapiens RCC2 protein protein.
          Length = 457

 Score =  126 bits (304), Expect = 1e-28
 Identities = 69/166 (41%), Positives = 94/166 (56%), Gaps = 7/166 (4%)
 Frame = +2

Query: 410 KTPGVLMIAGLVSWDLTAR----RDNNPTKRTHPNLYTFHKF---TDRRYRLIVSGCTAG 568
           K  G L+I G  +WDL  R    R     +    NL+  H++      R R +VSG  A 
Sbjct: 36  KCKGQLLIFGATNWDLIGRKEVPRQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 95

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 96  HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 155

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G V+A G+NK GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 156 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 201


>BC053908-1|AAH53908.1|  522|Homo sapiens RCC2 protein protein.
          Length = 522

 Score =  126 bits (304), Expect = 1e-28
 Identities = 68/166 (40%), Positives = 96/166 (57%), Gaps = 7/166 (4%)
 Frame = +2

Query: 410 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 568
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G V+A G+NK GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 266


>BC042141-1|AAH42141.1|  522|Homo sapiens regulator of chromosome
           condensation 2 protein.
          Length = 522

 Score =  126 bits (304), Expect = 1e-28
 Identities = 68/166 (40%), Positives = 96/166 (57%), Gaps = 7/166 (4%)
 Frame = +2

Query: 410 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 568
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G V+A G+NK GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 266


>AJ421269-1|CAD13148.1|  522|Homo sapiens RCC1-like protein protein.
          Length = 522

 Score =  126 bits (304), Expect = 1e-28
 Identities = 68/166 (40%), Positives = 96/166 (57%), Gaps = 7/166 (4%)
 Frame = +2

Query: 410 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 568
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 101 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 160

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 220

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G V+A G+NK GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 221 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 266


>AB040903-1|BAA95994.1|  564|Homo sapiens KIAA1470 protein protein.
          Length = 564

 Score =  126 bits (304), Expect = 1e-28
 Identities = 68/166 (40%), Positives = 96/166 (57%), Gaps = 7/166 (4%)
 Frame = +2

Query: 410 KTPGVLMIAGLVSWDLTARRDNNPTKRTH----PNLYTFHKF---TDRRYRLIVSGCTAG 568
           K  G L+I G  +WDL  R++    +  +     NL+  H++      R R +VSG  A 
Sbjct: 143 KCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA 202

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+T
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTET 262

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G V+A G+NK GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 263 GSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 308


>AL359612-1|CAB94882.1|  333|Homo sapiens hypothetical protein
           protein.
          Length = 333

 Score =  116 bits (278), Expect = 2e-25
 Identities = 57/121 (47%), Positives = 76/121 (62%)
 Frame = +2

Query: 524 TDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNII 703
           T  R R +VSG  A HS+L++ EG+ +++GRN  GQLG GDT     P L+  L  + I+
Sbjct: 2   TRGRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIV 61

Query: 704 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEF 883
            AA GR+HTL +T+TG V+A G+NK GQ GLGN T  +  P +I        K+ CGAEF
Sbjct: 62  SAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEF 121

Query: 884 S 886
           S
Sbjct: 122 S 122


>BC004933-1|AAH04933.1|  351|Homo sapiens RCC2 protein protein.
          Length = 351

 Score = 92.3 bits (219), Expect = 2e-18
 Identities = 45/95 (47%), Positives = 59/95 (62%)
 Frame = +2

Query: 602 YTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 781
           +++GRN  GQLG GDT     P L+  L  + I+ AA GR+HTL +T+TG V+A G+NK 
Sbjct: 1   WSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKM 60

Query: 782 GQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           GQ GLGN T  +  P +I        K+ CGAEFS
Sbjct: 61  GQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFS 95



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVG 718
           ++ + C   H++ ++E G  + FG N  GQLG G+  T +VP     +  G+ I   A G
Sbjct: 33  IVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQ-TDAVPSPAQIMYNGQPITKMACG 91

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 835
              ++ +   G +Y+ G  + GQ G  +    I +  RI
Sbjct: 92  AEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRI 130


>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
          Length = 4834

 Score = 84.2 bits (199), Expect = 6e-16
 Identities = 46/111 (41%), Positives = 64/111 (57%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
            C A  S+ +++ G  +T+G+    +LG G  V    P++V  L+GK I+H AVG  H L 
Sbjct: 3212 CGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLA 3271

Query: 737  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGAEFS 886
            VTD+G VYA GDN  GQ G G TT    KPT +  +E  +  +V CG+  S
Sbjct: 3272 VTDSGQVYAWGDNDHGQQGNGTTTVN-RKPTLVQGLEGQKITRVACGSSHS 3321



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 6/116 (5%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHT 730
           C + +S  ++ EGE YT+GR   G+LG G +   ++P LV  LKG  +I  A G     T
Sbjct: 558 CGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQT 617

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNT----TPQILKPTRINTMEHRXVKVGCGAEFS 886
           L VT+ G V++ GD   G+ G G +    TP++++  ++  ++   VKV CG++FS
Sbjct: 618 LAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIE--KLQDLD--VVKVRCGSQFS 669



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
 Frame = +2

Query: 557  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH--HT 730
            C + HS  ++  GE YT+G    G+LG GD  T+  P++V  L G  +I  A G     T
Sbjct: 3106 CGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQT 3165

Query: 731  LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCGAEFS 886
            L +TD G V++ GD   G+ G G +    + P  I  +  + V ++ CGA+FS
Sbjct: 3166 LALTDEGLVFSWGDGDFGKLGRGGSEGCNI-PQNIERLNGQGVCQIECGAQFS 3217



 Score = 65.7 bits (153), Expect = 2e-10
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
 Frame = +2

Query: 569  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
            H + +S EGE Y++G    G+LG G+      P ++  L+G  ++  A G  H+  VT  
Sbjct: 4050 HCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAA 4109

Query: 749  GCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGA 877
            G +Y  G  + G+ G  ++  Q LKP  +  ++ HR V + CG+
Sbjct: 4110 GDLYTWGKGRYGRLGHSDSEDQ-LKPKLVEALQGHRVVDIACGS 4152



 Score = 64.5 bits (150), Expect = 5e-10
 Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
 Frame = +2

Query: 557  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
            C +  SV +++ G  YT+G+    +LG G       P  V  L+GK +I  A G  H + 
Sbjct: 4204 CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVC 4263

Query: 737  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCGA 877
             T+ G VY  GDN  GQ G G TT  I +P  +  ++ + V +V CG+
Sbjct: 4264 CTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLVAALQGKKVNRVACGS 4310



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
 Frame = +2

Query: 569  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH--HTLFVT 742
            HS  V+  G+ YT+G+   G+LG  D+  +  P+LV  L+G  ++  A G     TL +T
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 4161

Query: 743  DTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH-RXVKVGCGAEFS 886
            D   V++ GD   G+ G G  +     P +I+++     VKV CG++FS
Sbjct: 4162 DDDTVWSWGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFS 4209



 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
 Frame = +2

Query: 569  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
            H+  ++ +G+ +++G    G+LG    +    P L+  LK K I   A G  H+  +T +
Sbjct: 3058 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSS 3117

Query: 749  GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCGA 877
            G +Y  G  + G+ G G+ T Q LKP  +  +  HR ++V CG+
Sbjct: 3118 GELYTWGLGEYGRLGHGDNTTQ-LKPKMVKVLLGHRVIQVACGS 3160



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELK----GKNIIHAAVGRHHTLF 736
           H + ++  GE Y++G    G+LG GDTV    P+++        GK+++H A G  ++  
Sbjct: 506 HYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAA 565

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           +T  G +Y  G    G+ G G++  + +          + + V CG+
Sbjct: 566 ITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGS 612



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/55 (47%), Positives = 31/55 (56%)
 Frame = +2

Query: 569  HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
            H V  +E+GE YT+G N  GQLG G T     P LV  L+GK +   A G  HTL
Sbjct: 4260 HCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 4314



 Score = 47.6 bits (108), Expect = 6e-05
 Identities = 23/77 (29%), Positives = 42/77 (54%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C +  S+ ++++G+ Y++G+    +LG G       P+L+  L+GK +I  A G  H L 
Sbjct: 664 CGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLA 723

Query: 737 VTDTGCVYACGDNKSGQ 787
           +T+   V++ G N   Q
Sbjct: 724 LTEDSEVHSWGSNDQCQ 740



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 27/89 (30%), Positives = 40/89 (44%)
 Frame = +2

Query: 596  EAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDN 775
            + + +G N   QLG        VP     L   N++  A G      VT  G VYACG+ 
Sbjct: 2960 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEA 3019

Query: 776  KSGQCGLGNTTPQILKPTRINTMEHRXVK 862
             +G+ GLG ++  +  P +I  +    VK
Sbjct: 3020 TNGRLGLGISSGTVPIPRQITALSSYVVK 3048



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/105 (21%), Positives = 51/105 (48%)
 Frame = +2

Query: 545 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 724
           +  G     ++ V+E G+ +++G    G+LG G +     P+L+ +L+  +++    G  
Sbjct: 608 VACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQ 667

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV 859
            ++ +T  G VY+ G   + + G G T   +  P  +  ++ + V
Sbjct: 668 FSIALTKDGQVYSWGKGDNQRLGHG-TEEHVRYPKLLEGLQGKKV 711



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
 Frame = +2

Query: 545  IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 724
            +  G     ++ +++EG  +++G    G+LG G +   ++P+ +  L G+ +     G  
Sbjct: 3156 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQ 3215

Query: 725  HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGA 877
             +L +T +G V+  G     + G G+    + KP  +  +   + V V  GA
Sbjct: 3216 FSLALTKSGVVWTWGKGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHVAVGA 3266



 Score = 41.1 bits (92), Expect = 0.005
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 593  GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF-VTDTGCVYACG 769
            G  Y +G N  GQLG  +     VP     L     +   +G   TLF VT  G +YA G
Sbjct: 3952 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQ-LIGGEQTLFAVTADGKLYATG 4010

Query: 770  DNKSGQCGLGNTTPQILKPTRINTMEHRXVK 862
                G+ G+G  T  +  PT + +++H  +K
Sbjct: 4011 YGAGGRLGIGG-TESVSTPTLLESIQHVFIK 4040



 Score = 40.7 bits (91), Expect = 0.007
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 7/117 (5%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHT 730
           C     +++S  G  YT   N+       DT+    P+LV  L  +NI+  A     HH 
Sbjct: 458 CAEKRFLILSRNGRVYTQAYNS-------DTLA---PQLVQGLASRNIVKIAAHSDGHHY 507

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-----XVKVGCGAEFS 886
           L +  TG VY+ G    G+ G G+T P + +P  I+    +      V + CG+ +S
Sbjct: 508 LALAATGEVYSWGCGDGGRLGHGDTVP-LEEPKVISAFSGKQAGKHVVHIACGSTYS 563



 Score = 37.9 bits (84), Expect = 0.048
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
 Frame = +2

Query: 581  VSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV---GRHHTLFVTDT 748
            V+ EG+ Y  G    G+LG G  + T  +P  +  L    +   AV   GRH T    D 
Sbjct: 3007 VTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVD- 3065

Query: 749  GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCGAEFS 886
            G V++ G+   G+ G   +     KP  I  ++ + ++ + CG+  S
Sbjct: 3066 GKVFSWGEGDDGKLG-HFSRMNCDKPRLIEALKTKRIRDIACGSSHS 3111


>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
          Length = 4861

 Score = 79.8 bits (188), Expect = 1e-14
 Identities = 44/117 (37%), Positives = 67/117 (57%), Gaps = 2/117 (1%)
 Frame = +2

Query: 542  LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
            ++   C   HS +V+ +G+ +TFG    G+LG G+T  + +PE V  L+G  I   A G 
Sbjct: 4136 VVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGL 4195

Query: 722  HHTLFVT-DTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCGAEFS 886
            +HTL V+ D   V+A GD   G+ GLGN+T +   P +I+ +    + KV CG +FS
Sbjct: 4196 NHTLAVSADGSMVWAFGDGDYGKLGLGNSTAK-SSPQKIDVLCGIGIKKVACGTQFS 4251



 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 35/113 (30%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
 Frame = +2

Query: 539  RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
            +L+ S  + GHS+ ++E GE +++G    G+LG G++  +  P  +  L+G+ ++  + G
Sbjct: 4083 QLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCG 4142

Query: 719  RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCG 874
              H+  VT  G ++  G+   G+ GLGNT+ + L P R+  +E ++  +V CG
Sbjct: 4143 FKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKL-PERVTALEGYQIGQVACG 4194



 Score = 67.3 bits (157), Expect = 7e-11
 Identities = 36/102 (35%), Positives = 54/102 (52%)
 Frame = +2

Query: 557  CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
            C    SV ++++G  YTFG++    L  G     + P+ +P L G  I   AVG  HTL 
Sbjct: 4246 CGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLA 4305

Query: 737  VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK 862
            +   G VYA G N  GQ GLG+T   + +PT +  ++ + V+
Sbjct: 4306 LASNGDVYAWGSNSEGQLGLGHTN-HVREPTLVTGLQGKNVR 4346



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 32/93 (34%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSV-PELVPELKGKNIIHAAVGRHHTLFVTDT 748
           S+ ++  G+ Y +G  AC  LG G +   ++ P+L+ EL    I+  ++G  H L ++  
Sbjct: 626 SLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHD 683

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
             VYA G+N  GQCG GN+T  I KP +++ ++
Sbjct: 684 NEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLD 716



 Score = 64.1 bits (149), Expect = 6e-10
 Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  V+E+GE YT+G    G+LG GD+ +R++P LV ++   N+   + G  HT+ ++  
Sbjct: 522 HSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDI--SNVGEVSCGSSHTIALSKD 579

Query: 749 G-CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
           G  V++ G   +G+ G G+T  ++ KP  I  ++   ++  C    S
Sbjct: 580 GRTVWSFGGGDNGKLGHGDTN-RVYKPKVIEALQGMFIRKVCAGSQS 625



 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 31/105 (29%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
 Frame = +2

Query: 566 GHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP-ELKGKNIIHAAVGRHHTLFVT 742
           GH++  + EGE +++G    G+LG G++ T+  P+L+   L+GK ++  + G  H+  VT
Sbjct: 468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVT 527

Query: 743 DTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + G +Y  G+   G+ G G++  + + PT +  + +   +V CG+
Sbjct: 528 EDGELYTWGEGDFGRLGHGDSNSRNI-PTLVKDISN-VGEVSCGS 570



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEA-YTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           C + H++ +S++G   ++FG    G+LG GDT     P+++  L+G  I     G   +L
Sbjct: 568 CGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSL 627

Query: 734 FVTDTGCVYACGDNKSGQC-GLGNTTPQILKPTRINTM-EHRXVKVGCG 874
            +T TG VYA G    G C G G++    L+P  I  +   R V V  G
Sbjct: 628 ALTSTGQVYAWG---CGACLGCGSSEATALRPKLIEELAATRIVDVSIG 673



 Score = 48.4 bits (110), Expect = 3e-05
 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
 Frame = +2

Query: 566 GHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           G + +VSE  E Y +G N+  QL  G       P+L P       I A  G++ T  ++ 
Sbjct: 363 GDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEA--GQYCTFVIST 420

Query: 746 TGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVK 862
            G V ACG    G+ GLG++  Q  LK  ++    HR +K
Sbjct: 421 DGSVRACGKGSYGRLGLGDSNNQSTLK--KLTFEPHRSIK 458



 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
 Frame = +2

Query: 563  AGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-HHTLFV 739
            A H++ ++  G+ Y +G N+ GQLG G T     P LV  L+GKN+   + GR H   + 
Sbjct: 4300 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 4359

Query: 740  TDTGCVYACGDNKSGQCGLGNTTPQ---ILKPTRINTMEHR 853
                   A G +   Q GL +T P     L+   I+T+  R
Sbjct: 4360 APPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRAR 4400



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 536  YRLIVSGCTAGHSVLVSEEGE-AYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAA 712
            Y++    C   H++ VS +G   + FG    G+LG G++  +S P+ +  L G  I   A
Sbjct: 4186 YQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVA 4245

Query: 713  VGRHHTLFVTDTGCVYACGDNK 778
             G   ++ +T  G VY  G ++
Sbjct: 4246 CGTQFSVALTKDGHVYTFGQDR 4267



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           H + +S + E Y +G N+ GQ G G+ T   + P+ V  L G  I   + G  H+L
Sbjct: 676 HCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSL 731


>X97668-1|CAA66258.1|  815|Homo sapiens XLRP3 protein.
          Length = 815

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>U57629-1|AAC50481.1|  815|Homo sapiens retinitis pigmentosa GTPase
           regulator protein.
          Length = 815

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>BC031624-1|AAH31624.1|  480|Homo sapiens RPGR protein protein.
          Length = 480

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>AL606748-2|CAI95407.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator protein.
          Length = 815

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>AK223491-1|BAD97211.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator variant protein.
          Length = 815

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>AJ318463-1|CAC86116.1|  815|Homo sapiens retinitis pigmentosa
           GTPase regulator protein.
          Length = 815

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 53.6 bits (123), Expect = 9e-07
 Identities = 31/110 (28%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+ +    + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGNPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>AJ238395-1|CAB54002.1|  646|Homo sapiens RPGR protein protein.
          Length = 646

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HS +V+   + Y FG N  GQLG G     S P  V  LK + +  AA GR+HTL 
Sbjct: 42  CGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLV 101

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQ-ILKPTRINTMEHRXVKVGCGAEFS 886
            T+ G VYA G N  GQ GLG+T  +         T EH+  ++  G+  S
Sbjct: 102 STEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152



 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHAAV 715
           ++I   C   H+V+++E    YTFG    GQLG G  +   S P+++  ++ + I + + 
Sbjct: 244 KVIQVACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISC 302

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLG--NTTPQILKPTRINTMEHRXVK-VGCG 874
           G +HT  +TD G +Y  GD + G+ GLG  N T   + PT  +      VK V CG
Sbjct: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFI-PTLCSNFLRFIVKLVACG 357



 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV--TRSVPELVPELKGKNIIHAAVGRHHT 730
           C   HS  V+ +GE Y FG    G+LG  + +      P+LV E+  K +I  A G  HT
Sbjct: 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEK-VIQVACGGEHT 255

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCG 874
           + +T+   VY  G  + GQ GLG    +  +P  I  +  + +  + CG
Sbjct: 256 VVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCG 303



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKN-IIHAAVGRH 724
           ++ C   H+++ +E G  Y  G N  GQLG GDT  R+   ++     ++ I   + G +
Sbjct: 91  LAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSN 150

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
            +  +T+ G ++  GDN  GQ GL N +  +  P ++ T+      + CG
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQV-TIGKPVSWISCG 198



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV-GCG 874
           +H + G  H+  VT    +Y  G N  GQ GLG+ +  I KPT +  ++   VK+  CG
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKS-AISKPTCVKALKPEKVKLAACG 95


>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
           protein.
          Length = 1024

 Score = 74.1 bits (174), Expect = 6e-13
 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL- 733
           C   HS L++++G  +TFG    GQLG   T     P LV EL G  +   A GR HTL 
Sbjct: 250 CGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLA 309

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILK-PTRINTME 847
           +V+D G V++ G  K GQ G G T  Q++  P ++++ E
Sbjct: 310 YVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSE 348



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  +S  G  Y++G+N CGQLG G T ++  P L+  L  + +   A G  H+  +T  
Sbjct: 202 HSTALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRI-NTMEHRXVKVGCG 874
           G ++  G  K GQ G  N+T   L+P  +   + +R  ++ CG
Sbjct: 262 GLLFTFGAGKHGQLG-HNSTQNELRPCLVAELVGYRVTQIACG 303



 Score = 65.7 bits (153), Expect = 2e-10
 Identities = 37/118 (31%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S+ GE + +G+N  GQLG G    + + P++V  L G  +   + 
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISA 198

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCGAEFS 886
           G  H+  ++ +G +Y+ G N+ GQ GLG+T  +   P+ I  ++++ V+ V CG   S
Sbjct: 199 GEAHSTALSMSGNIYSWGKNECGQLGLGHTESKD-DPSLIEGLDNQKVEFVACGGSHS 255



 Score = 35.9 bits (79), Expect = 0.20
 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
 Frame = +2

Query: 683 LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
           L+ K II    G +H+L ++  G ++A G N  GQ G+G      TTPQI++
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVE 186


>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
           protein.
          Length = 1024

 Score = 74.1 bits (174), Expect = 6e-13
 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL- 733
           C   HS L++++G  +TFG    GQLG   T     P LV EL G  +   A GR HTL 
Sbjct: 250 CGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLA 309

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILK-PTRINTME 847
           +V+D G V++ G  K GQ G G T  Q++  P ++++ E
Sbjct: 310 YVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSE 348



 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ +S  G  Y++G+N CGQLG G T ++  P L+  L  + +   A G  H+  +T  
Sbjct: 202 HSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRI-NTMEHRXVKVGCG 874
           G ++  G  K GQ G  N+T   L+P  +   + +R  ++ CG
Sbjct: 262 GLLFTFGAGKHGQLG-HNSTQNELRPCLVAELVGYRVTQIACG 303



 Score = 66.9 bits (156), Expect = 9e-11
 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 2/118 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S+ GE + +G+N  GQLG G    + + P++V  L G  +   + 
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISA 198

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCGAEFS 886
           G  H++ ++ +G +Y+ G N+ GQ GLG+T  +   P+ I  ++++ V+ V CG   S
Sbjct: 199 GEAHSMALSMSGNIYSWGKNECGQLGLGHTESKD-DPSLIEGLDNQKVEFVACGGSHS 255



 Score = 35.9 bits (79), Expect = 0.20
 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
 Frame = +2

Query: 683 LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
           L+ K II    G +H+L ++  G ++A G N  GQ G+G      TTPQI++
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVE 186


>AC004460-2|AAC06339.1|  371|Homo sapiens WUGSC:H_DJ1086D14.2
           protein.
          Length = 371

 Score = 73.7 bits (173), Expect = 8e-13
 Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C A   + +++ G  +T+G+    +LG    V    P++V  L+GK I+H AVG  H L 
Sbjct: 41  CGAQFLLALTKSGVVWTWGKGDYFRLGHRSDVHVRKPQVVEGLRGKKIVHVAVGAQHCLA 100

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCGAEFS 886
           V D+G VYA GDN  GQ G G TT    KP  +  +E + +  V CG+  S
Sbjct: 101 VMDSGQVYAWGDNDHGQQGNGTTTVN-RKPMLVQGLEGQKIMCVACGSSHS 150


>BC029052-1|AAH29052.1|  551|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 551

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+  +
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 845 EH-RXVKVGCG 874
           +  R  +V CG
Sbjct: 255 QGIRVQRVACG 265



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-XVKVGCG 874
            G V+A G N SGQ G G+T  Q +       ++++  V + CG
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACG 213



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 38/108 (35%), Positives = 55/108 (50%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 722 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
            HTL +TD G VYA G N  GQ G GN + Q   PT +   + R +++
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEI 313



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
 Frame = +2

Query: 512 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 679
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 680 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT--MEH 850
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I+T     
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 851 RXVKVGCGAEFS 886
           + ++V CG+  S
Sbjct: 153 QVIEVACGSYHS 164



 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++++++EG+ Y +G N+ GQLG G+   +S P  V   K + I  AA    HT  
Sbjct: 264 CGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSA 323

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 324 AKTQGGHVYMWG 335


>AY341245-1|AAP88928.1|  551|Homo sapiens chromosome condensation
           1-like protein.
          Length = 551

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+  +
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 845 EH-RXVKVGCG 874
           +  R  +V CG
Sbjct: 255 QGIRVQRVACG 265



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-XVKVGCG 874
            G V+A G N SGQ G G+T  Q +       ++++  V + CG
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACG 213



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 38/108 (35%), Positives = 55/108 (50%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 722 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
            HTL +TD G VYA G N  GQ G GN + Q   PT +   + R +++
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEI 313



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
 Frame = +2

Query: 512 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 679
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 680 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT--MEH 850
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I+T     
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 851 RXVKVGCGAEFS 886
           + ++V CG+  S
Sbjct: 153 QVIEVACGSYHS 164



 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++++++EG+ Y +G N+ GQLG G+   +S P  V   K + I  AA    HT  
Sbjct: 264 CGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSA 323

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 324 AKTQGGHVYMWG 335


>AL157813-1|CAH70795.1|  551|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 551

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+  +
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 845 EH-RXVKVGCG 874
           +  R  +V CG
Sbjct: 255 QGIRVQRVACG 265



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-XVKVGCG 874
            G V+A G N SGQ G G+T  Q +       ++++  V + CG
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACG 213



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 38/108 (35%), Positives = 55/108 (50%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 722 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
            HTL +TD G VYA G N  GQ G GN + Q   PT +   + R +++
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEI 313



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
 Frame = +2

Query: 512 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 679
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 680 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT--MEH 850
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I+T     
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 851 RXVKVGCGAEFS 886
           + ++V CG+  S
Sbjct: 153 QVIEVACGSYHS 164



 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++++++EG+ Y +G N+ GQLG G+   +S P  V   K + I  AA    HT  
Sbjct: 264 CGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSA 323

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 324 AKTQGGHVYMWG 335


>AF060219-1|AAC79987.1|  551|Homo sapiens RCC1-like G exchanging
           factor RLG protein.
          Length = 551

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 136 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 195

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+  +
Sbjct: 196 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 254

Query: 845 EH-RXVKVGCG 874
           +  R  +V CG
Sbjct: 255 QGIRVQRVACG 265



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 169

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-XVKVGCG 874
            G V+A G N SGQ G G+T  Q +       ++++  V + CG
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACG 213



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 38/108 (35%), Positives = 55/108 (50%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 207 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 266

Query: 722 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
            HTL +TD G VYA G N  GQ G GN + Q   PT +   + R +++
Sbjct: 267 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEI 313



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
 Frame = +2

Query: 512 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 679
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 34  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 93

Query: 680 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT--MEH 850
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I+T     
Sbjct: 94  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 152

Query: 851 RXVKVGCGAEFS 886
           + ++V CG+  S
Sbjct: 153 QVIEVACGSYHS 164



 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++++++EG+ Y +G N+ GQLG G+   +S P  V   K + I  AA    HT  
Sbjct: 264 CGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSA 323

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 324 AKTQGGHVYMWG 335


>AB209543-1|BAD92780.1|  556|Homo sapiens RCC1-like G exchanging
           factor RLG variant protein.
          Length = 556

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  L   H  T+   + ++   C + HS++++ +GE + +G N  GQ+G G TV + +P
Sbjct: 141 TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIP 200

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L+ K ++  A G+   + V DTG VY  G N +GQ GLGN+  Q   P R+  +
Sbjct: 201 RRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-PTPCRVAAL 259

Query: 845 EH-RXVKVGCG 874
           +  R  +V CG
Sbjct: 260 QGIRVQRVACG 270



 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H VL + EGE +T+G NA  QLG G T    VP  +   L  K +I  A G +H+L +T 
Sbjct: 115 HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTS 174

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHR-XVKVGCG 874
            G V+A G N SGQ G G+T  Q +       ++++  V + CG
Sbjct: 175 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACG 218



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 38/108 (35%), Positives = 55/108 (50%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C     + V + GE Y +G N  GQLG G++  +  P  V  L+G  +   A G 
Sbjct: 212 VVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGY 271

Query: 722 HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
            HTL +TD G VYA G N  GQ G GN + Q   PT +   + R +++
Sbjct: 272 AHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY-PTPVTVEKDRIIEI 318



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
 Frame = +2

Query: 512 FHKFTDRRYRLIVSGC---TAGHSVLVSE-EGEAYTFGRNACGQLGFGDTVTRSVPELVP 679
           F   ++   +LI   C   +AG+ VL +    E +  G N CG LG GD  +   P  + 
Sbjct: 39  FSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLD 98

Query: 680 ELKGKNIIHAAVGR-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT--MEH 850
            L GK I   + G   H +  T  G V+  G N   Q G G TT   L P  I+T     
Sbjct: 99  SLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNG-TTNHGLVPCHISTNLSNK 157

Query: 851 RXVKVGCGAEFS 886
           + ++V CG+  S
Sbjct: 158 QVIEVACGSYHS 169



 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++++++EG+ Y +G N+ GQLG G+   +S P  V   K + I  AA    HT  
Sbjct: 269 CGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSA 328

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 329 AKTQGGHVYMWG 340


>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 700
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  I ++ + + V+V CG
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 333



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 252



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 304



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 718
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 301 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338


>AY650033-1|AAV66579.1|  979|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 3 protein.
          Length = 979

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 700
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  I ++ + + V+V CG
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 333



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 252



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 304



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 718
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 301 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338


>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 1 protein.
          Length = 1057

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 700
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  I ++ + + V+V CG
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 333



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 252



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 304



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 718
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 301 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338


>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 700
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  I ++ + + V+V CG
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 333



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 252



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 304



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 718
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 301 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338


>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
           protein.
          Length = 1049

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 45/119 (37%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNI 700
           F ++R R +  GC   H+V V ++G  YT G N  GQLG   +  R  PE V  L  +NI
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKS--RKKPEQVVALDAQNI 86

Query: 701 IHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           +  + G  HTL + D G VYA G +  GQ GL  +   I  P  I ++ + + V+V CG
Sbjct: 87  VAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145



 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 240 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 299

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 300 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 333



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 138 QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 197

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 198 GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 252



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 201 HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 261 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 304



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGF-GDTVTRSVPELVPELKGKNIIHAAVG 718
           ++   C   H++ ++++G+ Y +G ++ GQLG  G      VP  +  L    I+  A G
Sbjct: 86  IVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
            +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 146 YYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 185



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 301 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 338


>AF224249-1|AAO27475.1|  328|Homo sapiens HERC2 protein.
          Length = 328

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH--HT 730
           C + HS  ++  GE YT+G    G+LG GD  T+  P++V  L G  +I  A G     T
Sbjct: 144 CGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQT 203

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCGAEFS 886
           L +TD G V++ GD   G+ G G +    + P  I  +  + V ++ CGA+FS
Sbjct: 204 LALTDEGLVFSWGDGDFGKLGRGGSEGCNI-PQNIERLNGQGVCQIECGAQFS 255



 Score = 69.7 bits (163), Expect = 1e-11
 Identities = 35/79 (44%), Positives = 48/79 (60%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C A  S+ +++ G  +T+G+    +LG G  V    P++V  L+GK I+H AVG  H L 
Sbjct: 250 CGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLA 309

Query: 737 VTDTGCVYACGDNKSGQCG 793
           VTD+G VYA GDN  GQ G
Sbjct: 310 VTDSGQVYAWGDNDHGQQG 328



 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 32/104 (30%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H+  ++ +G+ + +G    G+LG    +    P L+  LK K I   A G  H+  +T +
Sbjct: 96  HATALTVDGKVFWWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSS 155

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCGA 877
           G +Y  G  + G+ G G+ T Q LKP  +  +  HR ++V CG+
Sbjct: 156 GELYTWGLGEYGRLGHGDNTTQ-LKPKMVKVLLGHRVIQVACGS 198



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 27/85 (31%), Positives = 38/85 (44%)
 Frame = +2

Query: 608 FGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQ 787
           +G N   QLG        VP     L   N++  A G      VT  G VYACG+  +G+
Sbjct: 2   WGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGR 61

Query: 788 CGLGNTTPQILKPTRINTMEHRXVK 862
            GLG ++  +  P +I  +    VK
Sbjct: 62  LGLGISSGTVPIPRQITALSSYVVK 86



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
 Frame = +2

Query: 545 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRH 724
           +  G     ++ +++EG  +++G    G+LG G +   ++P+ +  L G+ +     G  
Sbjct: 194 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQ 253

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGA 877
            +L +T +G V+  G     + G G+    + KP  +  +   + V V  GA
Sbjct: 254 FSLALTKSGVVWTWGKGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHVAVGA 304



 Score = 36.3 bits (80), Expect = 0.15
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%)
 Frame = +2

Query: 581 VSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV---GRHHTLFVTDT 748
           V+ EG+ Y  G    G+LG G  + T  +P  +  L    +   AV   GRH T    D 
Sbjct: 45  VTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVD- 103

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-VGCGAEFS 886
           G V+  G+   G+ G   +     KP  I  ++ + ++ + CG+  S
Sbjct: 104 GKVFWWGEGDDGKLG-HFSRMNCDKPRLIEALKTKRIRDIACGSSHS 149


>BC038104-1|AAH38104.1|  355|Homo sapiens RCBTB1 protein protein.
          Length = 355

 Score = 70.9 bits (166), Expect = 6e-12
 Identities = 43/131 (32%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
 Frame = +2

Query: 491 THPNLYTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           T+  + T    T+   + +V   C + HS+ ++ +GE + +G N CGQ+G G T  +  P
Sbjct: 112 TNQGIATVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTP 171

Query: 668 ELVPE-LKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTM 844
             V   L  K ++  A G+  ++ V D G VY  G N +GQ GLGN   Q L P R+  +
Sbjct: 172 RKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRVAAL 230

Query: 845 EHRXV-KVGCG 874
               V ++ CG
Sbjct: 231 HSVCVNQIVCG 241



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 38/109 (34%), Positives = 52/109 (47%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
             HTL +TD G +YA G N  GQ G GN    +L P  I   + R V++
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEI 289



 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 3/119 (2%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 719 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI--NTMEHRXVKVGCGAEFS 886
              H L  T+ G VYA G N   Q G G TT Q +   ++  N +  + V+V CG+  S
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIATVQVCTNLLIKQVVEVACGSHHS 140



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++ +++EG  Y +G N  GQLG G+      P  +   K + +  AA    HT  
Sbjct: 240 CGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSA 299

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 300 AKTQGGHVYMWG 311


>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
          Length = 1054

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 45  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 102

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           ++D G +++ G    GQ GL  T   +  P  I  +  + + +V CG
Sbjct: 103 LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 149



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 244 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 303

Query: 710 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 805
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 304 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 336



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 718
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 90  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 149

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
             H L +   G  +  G N  GQ GLG   P    P R+ ++E
Sbjct: 150 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLE 192



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 148 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 207

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGAE 880
            ++ +G V+  G N +GQ GL +   +   P  +  +   + V + CG E
Sbjct: 208 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEE 256



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 28/104 (26%), Positives = 47/104 (45%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 205 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 264

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +   ++     +  M     ++ CG +
Sbjct: 265 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQ 308


>BC038960-1|AAH38960.1|  368|Homo sapiens HERC3 protein protein.
          Length = 368

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 41  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 98

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           ++D G +++ G    GQ GL  T   +  P  I  +  + + +V CG
Sbjct: 99  LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 299

Query: 710 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 805
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 300 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 718
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 86  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
             H L +   G  +  G N  GQ GLG   P    P R+ ++E
Sbjct: 146 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLE 188



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 144 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 203

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGAE 880
            ++ +G V+  G N +GQ GL +   +   P  +  +   + V + CG E
Sbjct: 204 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEE 252



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 28/104 (26%), Positives = 47/104 (45%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 201 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +   ++     +  M     ++ CG +
Sbjct: 261 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQ 304


>AL139321-5|CAH71047.1|  531|Homo sapiens regulator of chromosome
           condensation (RCC1) and BTB (POZ) domain containing pro
           protein.
          Length = 531

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 715
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+  +    V ++ CG
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRVAALHSVCVNQIVCG 241



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 38/109 (34%), Positives = 52/109 (47%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
             HTL +TD G +YA G N  GQ G GN    +L P  I   + R V++
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEI 289



 Score = 62.9 bits (146), Expect = 1e-09
 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 548 VSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-H 724
           V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G   
Sbjct: 26  VFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGP 85

Query: 725 HTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI--NTMEHRXVKVGCGAEFS 886
           H L  T+ G VYA G N   Q G G TT Q + P ++  N +  + V+V CG+  S
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVACGSHHS 140



 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH--RXVKVGCG 874
            G V+A G N  GQ G G+T  Q   P ++    H  R V + CG
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ-PTPRKVTNCLHIKRVVGIACG 189



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++ +++EG  Y +G N  GQLG G+      P  +   K + +  AA    HT  
Sbjct: 240 CGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSA 299

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 300 AKTQGGHVYMWG 311


>AK096654-1|BAC04833.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39335 fis, clone OCBBF2017398, moderately
           similar to Homo sapiens RCC1-like G exchanging factor
           RLG mRNA. ).
          Length = 531

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 715
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+  +    V ++ CG
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRVAALHSVCVNQIVCG 241



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 38/109 (34%), Positives = 52/109 (47%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
             HTL +TD G +YA G N  GQ G GN    +L P  I   + R V++
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEI 289



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 3/119 (2%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 719 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI--NTMEHRXVKVGCGAEFS 886
              H L  T+ G VYA G N   Q G G TT Q + P ++  N +  + V+V CG+  S
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVACGSHHS 140



 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH--RXVKVGCG 874
            G V+A G N  GQ G G+T  Q   P ++    H  R V + CG
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ-PTPRKVTNCLHIKRVVGIACG 189



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++ +++EG  Y +G N  GQLG G+      P  +   K + +  AA    HT  
Sbjct: 240 CGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSA 299

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 300 AKTQGGHVYMWG 311


>AJ319660-1|CAC40027.1|  531|Homo sapiens guanine nucleotide
           exchange factor protein.
          Length = 531

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 715
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+  +    V ++ CG
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRVAALHSVCVNQIVCG 241



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 38/109 (34%), Positives = 52/109 (47%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
             HTL +TD G +YA G N  GQ G GN    +L P  I   + R V++
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEI 289



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 3/119 (2%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 719 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI--NTMEHRXVKVGCGAEFS 886
              H L  T+ G VYA G N   Q G G TT Q + P ++  N +  + V+V CG+  S
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVACGSHHS 140



 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH--RXVKVGCG 874
            G V+A G N  GQ G G+T  Q   P ++    H  R V + CG
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ-PTPRKVTNCLHIKRVVGIACG 189



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++ +++EG  Y +G N  GQLG G+      P  +   K + +  AA    HT  
Sbjct: 240 CGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSA 299

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 300 AKTQGGHVYMWG 311


>AF334406-1|AAK38372.1|  531|Homo sapiens CLLL7 protein protein.
          Length = 531

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPE-LKGKNIIHAAV 715
           +++   C + HS+ ++ +GE + +G N CGQ+G G T  +  P  V   L  K ++  A 
Sbjct: 129 QVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIAC 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           G+  ++ V D G VY  G N +GQ GLGN   Q L P R+  +    V ++ CG
Sbjct: 189 GQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQ-LTPVRVAALHSVCVNQIVCG 241



 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 38/109 (34%), Positives = 52/109 (47%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           R++   C    S+ V + GE Y +G N  GQLG G+   +  P  V  L    +     G
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKV 865
             HTL +TD G +YA G N  GQ G GN    +L P  I   + R V++
Sbjct: 242 YAHTLALTDEGLLYAWGANTYGQLGTGNKN-NLLSPAHIMVEKERVVEI 289



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 3/119 (2%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVG 718
           ++ V G +A  ++ V++  E + FG N    LG GD  +  VP+ +  L GK I   + G
Sbjct: 23  KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYG 82

Query: 719 R-HHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI--NTMEHRXVKVGCGAEFS 886
              H L  T+ G VYA G N   Q G G TT Q + P ++  N +  + V+V CG+  S
Sbjct: 83  SGPHVLLSTEDGVVYAWGHNGYSQLGNG-TTNQGIAPVQVCTNLLIKQVVEVACGSHHS 140



 Score = 60.9 bits (141), Expect = 6e-09
 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP-ELVPELKGKNIIHAAVGRHHTLFVTD 745
           H +L +E+G  Y +G N   QLG G T     P ++   L  K ++  A G HH++ +  
Sbjct: 86  HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145

Query: 746 TGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH--RXVKVGCG 874
            G V+A G N  GQ G G+T  Q   P ++    H  R V + CG
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQ-PTPRKVTNCLHIKRVVGIACG 189



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   H++ +++EG  Y +G N  GQLG G+      P  +   K + +  AA    HT  
Sbjct: 240 CGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSA 299

Query: 737 V-TDTGCVYACG 769
             T  G VY  G
Sbjct: 300 AKTQGGHVYMWG 311


>AC098582-1|AAY41038.1|  382|Homo sapiens unknown protein.
          Length = 382

 Score = 70.5 bits (165), Expect = 7e-12
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C   HSV + E+GE YT G N  GQLG      +  PE +  L  ++IIH A G  H+L 
Sbjct: 41  CGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNK--PEQIGALADQHIIHVACGESHSLA 98

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCG 874
           ++D G +++ G    GQ GL  T   +  P  I  +  + + +V CG
Sbjct: 99  LSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145



 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+ ++++ G  +TFG  +CGQLG         P  V EL G  +   
Sbjct: 240 RTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQI 299

Query: 710 AVGRHHTL-FVTDTGCVYACGDNKSGQCGLGNT 805
           A GR HTL FV  +G +YA G    GQ G G+T
Sbjct: 300 ACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332



 Score = 63.7 bits (148), Expect = 9e-10
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTV-TRSVPELVPELKGKNIIHAAVG 718
           +I   C   HS+ +S+ G+ +++G  + GQLG   T  + +VP L+ +L  + I+  + G
Sbjct: 86  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145

Query: 719 RHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
             H L +   G  +  G N  GQ GLG   P    P R+ ++E
Sbjct: 146 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLE 188



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           C   H + ++ +G+ +T+G+N+ GQLG G +  +++ P+ V  L+G  +   A G  H+ 
Sbjct: 144 CGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSF 203

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME-HRXVKVGCGAE 880
            ++ +G V+  G N +GQ GL +   +   P  +  +   + V + CG E
Sbjct: 204 ALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEE 252



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 28/104 (26%), Positives = 47/104 (45%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  +S  G  + +G N  GQLG  D   R  P  V  L+ + +++ + G  HT  +T +
Sbjct: 201 HSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS 260

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +   ++     +  M     ++ CG +
Sbjct: 261 GGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQ 304


>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
           tyrosine kinase-beta protein.
          Length = 1196

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 300 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 340



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
           tyrosine kinase-alpha protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 300 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 340



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
           agammaglobulinemia tyrosine kinase protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 300 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 340



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
           agammaglobulinemia tyrosine kinase protein.
          Length = 1353

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 247

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 248 GCVYTFGLNIFHQLGI 263



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 240 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 299

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 300 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 340



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 143 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 202

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 203 HGPGGRLGHGD 213


>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
          Length = 1187

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 184 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 243

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 244 GCVYTFGLNIFHQLGI 259



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 236 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 295

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 296 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 336



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 139 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 198

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 199 HGPGGRLGHGD 209


>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
          Length = 1379

 Score = 68.1 bits (159), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HSV +S++G+ YT G    G+LG GD  T  VP LV  L G N    A  + HT+ +T+ 
Sbjct: 214 HSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTED 273

Query: 749 GCVYACGDNKSGQCGL 796
           GCVY  G N   Q G+
Sbjct: 274 GCVYTFGLNIFHQLGI 289



 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPE--LKGKNIIHAAVGRHHTLFV 739
           H+V+++E+G  YTFG N   QLG     +  +VP  +    LKG+ II  A GR HT+  
Sbjct: 266 HTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLW 325

Query: 740 TDTGCVYACGDNKSGQCGL---GNTTPQILKPTRINTMEHRXV 859
           T    VY  G N  GQ G     N    +  P +++ + H+ +
Sbjct: 326 T-REAVYTMGLN-GGQLGCLLDPNGEKCVTAPRQVSALHHKDI 366



 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 596 EAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           + YT+G N    LG G   ++  PELV      G  I    + + H++F++  G VY CG
Sbjct: 169 DVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCG 228

Query: 770 DNKSGQCGLGN 802
               G+ G G+
Sbjct: 229 HGPGGRLGHGD 239


>BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.
          Length = 651

 Score = 67.3 bits (157), Expect = 7e-11
 Identities = 36/102 (35%), Positives = 54/102 (52%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C    SV ++++G  YTFG++    L  G     + P+ +P L G  I   AVG  HTL 
Sbjct: 36  CGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLA 95

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK 862
           +   G VYA G N  GQ GLG+T   + +PT +  ++ + V+
Sbjct: 96  LASNGDVYAWGSNSEGQLGLGHTN-HVREPTLVTGLQGKNVR 136



 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
 Frame = +2

Query: 563 AGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR-HHTLFV 739
           A H++ ++  G+ Y +G N+ GQLG G T     P LV  L+GKN+   + GR H   + 
Sbjct: 90  AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 149

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQ---ILKPTRINTMEHR 853
                  A G +   Q GL +T P     L+   I+T+  R
Sbjct: 150 APPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRAR 190


>AF225407-1|AAO27483.1|  409|Homo sapiens HERC2 protein.
          Length = 409

 Score = 64.5 bits (150), Expect = 5e-10
 Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C +  SV +++ G  YT+G+    +LG G       P  V  L+GK +I  A G  H + 
Sbjct: 108 CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVC 167

Query: 737 VTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXV-KVGCGA 877
            T+ G VY  GDN  GQ G G TT  I +P  +  ++ + V +V CG+
Sbjct: 168 CTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLVAALQGKKVNRVACGS 214



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR--HHTLFVT 742
           HS  V+  G+ YT+G+   G+LG  D+  +  P+LV  L+G  ++  A G     TL +T
Sbjct: 6   HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 65

Query: 743 DTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEH-RXVKVGCGAEFS 886
           D   V++ GD   G+ G G  +     P +I+++     VKV CG++FS
Sbjct: 66  DDDTVWSWGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFS 113



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/55 (47%), Positives = 31/55 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTL 733
           H V  +E+GE YT+G N  GQLG G T     P LV  L+GK +   A G  HTL
Sbjct: 164 HCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTL 218


>AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 90  RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 149

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 150 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 183



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 51  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 110

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 111 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 154



 Score = 53.6 bits (123), Expect = 9e-07
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = +2

Query: 578 LVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGC 754
           +     E + +G+N  GQLG G D   ++ P+L+  L G   +  A G  H+  +T +G 
Sbjct: 1   MAESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60

Query: 755 VYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 61  IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 102



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 151 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 188


>AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 90  RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 149

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 150 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 183



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 51  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 110

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 111 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 154



 Score = 53.6 bits (123), Expect = 9e-07
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = +2

Query: 578 LVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGC 754
           +     E + +G+N  GQLG G D   ++ P+L+  L G   +  A G  H+  +T +G 
Sbjct: 1   MAESASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60

Query: 755 VYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 61  IFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 102



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 151 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 188


>AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.
          Length = 953

 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHA 709
           R  +++   C   H+  +++EG  +TFG    GQLG   T     P  V EL G  +   
Sbjct: 136 RSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEI 195

Query: 710 AVGRHHT-LFVTDTGCVYACGDNKSGQCGLGNTT 808
           A GR HT  FV  +G +Y+ G   +GQ G G+T+
Sbjct: 196 ACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS 229



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           +++   C   HS+ +S+  E + +G+N  GQLG G D   ++ P+L+  L G   +  A 
Sbjct: 34  QIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAA 93

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G  H+  +T +G ++  G NK GQ GL +   + +     +    + V + CG +
Sbjct: 94  GGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGED 148



 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 32/104 (30%), Positives = 50/104 (48%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS +++  G  + +GRN  GQLG  D   R VP L+  L+ + I++   G  HT  +T  
Sbjct: 97  HSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 156

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAE 880
           G V+  G    GQ G  +T+ +I        M     ++ CG +
Sbjct: 157 GGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQ 200



 Score = 37.1 bits (82), Expect = 0.085
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
 Frame = +2

Query: 674 VPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLG-----NTTPQILK 823
           +  L    I+  A G +H+L ++    V+  G NK GQ GLG      T+PQ+LK
Sbjct: 27  IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLK 81



 Score = 30.7 bits (66), Expect = 7.3
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
 Frame = +2

Query: 557 CTAGH-SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVP 667
           C   H S  V   G  Y+FG    GQLG G T  R  P
Sbjct: 197 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 234


>BC112101-1|AAI12102.1|  979|Homo sapiens NIMA related kinase 9
           protein.
          Length = 979

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 416 QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 476 FFLSNPVEQVSCG 488



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 641 NLLGGPLGGKQVIRVSCGDEFT 662


>BC093881-1|AAH93881.1|  979|Homo sapiens NIMA (never in mitosis
           gene a)- related kinase 9 protein.
          Length = 979

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 416 QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 476 FFLSNPVEQVSCG 488



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 641 NLLGGPLGGKQVIRVSCGDEFT 662


>AY080896-1|AAL87410.1|  979|Homo sapiens NIMA-family kinase NERCC1
           protein.
          Length = 979

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 416 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 476 FFLSNPVEQVSCG 488



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 641 NLLGGPLGGKQVIRVSCGDEFT 662


>AY048580-1|AAL05428.1|  979|Homo sapiens NIMA-related kinase Nek8
           protein.
          Length = 979

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 356 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 415

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 416 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 475

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 476 FFLSNPVEQVSCG 488



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 598 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 655

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 656 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 687



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 521 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 580

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 581 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 640

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 641 NLLGGPLGGKQVIRVSCGDEFT 662


>AC007055-4|AAD31939.1|  414|Homo sapiens protein ( Homo sapiens
           chromosome 14 clone BAC 201F1 map 14q24.3, complete
           sequence. ).
          Length = 414

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 26  KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 85

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 86  QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 145

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 146 FFLSNPVEQVSCG 158



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 268 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 325

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 326 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 357



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 191 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 250

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 251 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 310

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 311 NLLGGPLGGKQVIRVSCGDEFT 332


>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
          Length = 1011

 Score = 61.7 bits (143), Expect = 3e-09
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
 Frame = +2

Query: 518 KFTDRRYRLIVSGCTAG-------HSVLVSEEGEAYTF-----GRNACGQLGFGDTVTRS 661
           K T ++  +I SGC+A        H  +V+ E E YT+     G    GQLG GD  +  
Sbjct: 388 KSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYR 447

Query: 662 VPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT-PQILKPTRIN 838
            P+ V +L+GK I   + G   T+ VTD G +YA G +  G  G+     P++L+P ++N
Sbjct: 448 QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLN 507

Query: 839 TMEHRXV-KVGCG 874
                 V +V CG
Sbjct: 508 FFLSNPVEQVSCG 520



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 533 RYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTR-SVPELVPELKGKNIIHA 709
           + R I  G T  H+  + E G   TFG N CGQLG G+   R  +  L   L GK +I  
Sbjct: 630 KIRTIAPGKT--HTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRV 687

Query: 710 AVGRHHTLFVTDTGCVYACGDNKSGQCGLGNT 805
           + G   T+  TD   ++A G+  +G+  +  T
Sbjct: 688 SCGDEFTIAATDDNHIFAWGNGGNGRLAMTPT 719



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
 Frame = +2

Query: 506 YTFHKFTDRRYRLIVS-GCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVT--------R 658
           YT  K    +  +IV+  C    + L+++ G+    G N   +LG    ++         
Sbjct: 553 YTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH 612

Query: 659 SVP-----ELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQI-L 820
            VP      L  +L    I   A G+ HT  + + G +   G NK GQ G+GN   ++ +
Sbjct: 613 EVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGI 672

Query: 821 KPTRINTMEHRXVKVGCGAEFS 886
                     + ++V CG EF+
Sbjct: 673 NLLGGPLGGKQVIRVSCGDEFT 694


>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
           protein.
          Length = 1022

 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 733
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
            ++    V++ G N  GQ GLG   P    P R+ ++E
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLE 179



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 244



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG+
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGS 296



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 722 HHTL-FVTDTGCVYACGDNKS 781
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           G V+A G    GQ G+G        P +I T+ + + ++V CG
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCG 136



 Score = 37.5 bits (83), Expect = 0.064
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-V 865
           G  ++ AA G  H+L +     V +CGDN  GQ G        L P  I  +E   V  V
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGEL-PEPIQALETLIVDLV 80

Query: 866 GCGAEFS 886
            CG E S
Sbjct: 81  SCGKEHS 87


>AY653203-1|AAV66897.1|  322|Homo sapiens truncated HERC6 protein.
          Length = 322

 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 733
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
            ++    V++ G N  GQ GLG   P    P R+ ++E
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLE 179



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 244



 Score = 54.8 bits (126), Expect = 4e-07
 Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCG 295



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           G V+A G    GQ G+G        P +I T+ + + ++V CG
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCG 136



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/50 (32%), Positives = 30/50 (60%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG 691
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG 287



 Score = 37.5 bits (83), Expect = 0.064
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-V 865
           G  ++ AA G  H+L +     V +CGDN  GQ G        L P  I  +E   V  V
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGEL-PEPIQALETLIVDLV 80

Query: 866 GCGAEFS 886
            CG E S
Sbjct: 81  SCGKEHS 87


>AY653202-1|AAV66896.1|  364|Homo sapiens truncated HERC6 protein.
          Length = 364

 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 733
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
            ++    V++ G N  GQ GLG   P    P R+ ++E
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLE 179



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 244



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG+
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGS 296



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 722 HHTL-FVTDTGCVYACGDNKS 781
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           G V+A G    GQ G+G        P +I T+ + + ++V CG
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCG 136



 Score = 37.5 bits (83), Expect = 0.064
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-V 865
           G  ++ AA G  H+L +     V +CGDN  GQ G        L P  I  +E   V  V
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGEL-PEPIQALETLIVDLV 80

Query: 866 GCGAEFS 886
            CG E S
Sbjct: 81  SCGKEHS 87


>AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant
           protein.
          Length = 986

 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 733
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
            ++    V++ G N  GQ GLG   P    P R+ ++E
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLE 179



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 244



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG+
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGS 296



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 722 HHTL-FVTDTGCVYACGDNKS 781
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           G V+A G    GQ G+G        P +I T+ + + ++V CG
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCG 136



 Score = 37.5 bits (83), Expect = 0.064
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-V 865
           G  ++ AA G  H+L +     V +CGDN  GQ G        L P  I  +E   V  V
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGEL-PEPIQALETLIVDLV 80

Query: 866 GCGAEFS 886
            CG E S
Sbjct: 81  SCGKEHS 87


>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
          Length = 1022

 Score = 60.5 bits (140), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRS-VPELVPELKGKNIIHAAVGRHHTL 733
           C   HS+ V  +G  + +G  + GQLG G+    S  P+ +  L    II  + G +H+L
Sbjct: 82  CGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSL 141

Query: 734 FVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTME 847
            ++    V++ G N  GQ GLG   P    P R+ ++E
Sbjct: 142 ALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLE 179



 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 129 KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 188

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 189 GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 244



 Score = 55.2 bits (127), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 192 HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG+
Sbjct: 252 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCGS 296



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G  +     G 
Sbjct: 238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGS 296

Query: 722 HHTL-FVTDTGCVYACGDNKS 781
           +HTL +V  TG V + G   S
Sbjct: 297 YHTLAYVHTTGQVVSFGHGPS 317



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+L+       + G N+ GQLG        +PE +  L+   +   + G+ H+L V   
Sbjct: 34  HSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHK 93

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRINTM-EHRXVKVGCG 874
           G V+A G    GQ G+G        P +I T+ + + ++V CG
Sbjct: 94  GRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCG 136



 Score = 37.5 bits (83), Expect = 0.064
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVK-V 865
           G  ++ AA G  H+L +     V +CGDN  GQ G        L P  I  +E   V  V
Sbjct: 22  GAELLQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGEL-PEPIQALETLIVDLV 80

Query: 866 GCGAEFS 886
            CG E S
Sbjct: 81  SCGKEHS 87


>BC029174-1|AAH29174.1|  812|Homo sapiens ALS2 protein protein.
          Length = 812

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 622



 Score = 57.6 bits (133), Expect = 6e-08
 Identities = 31/78 (39%), Positives = 44/78 (56%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y CG+N +GQC + N
Sbjct: 110 GVAYMCGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 527  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 706
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 707  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 470 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 643
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 644 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 527  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 706
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 707  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 470 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 643
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 644 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
          Length = 4640

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 527  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 706
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 707  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 470 DNNPTK-RTHPNLYTFHKFTDRRYRLIV-SGCTAGHSVLVSEEGEAYTFGRNACGQLGFG 643
           D   TK R     Y   K      +++V + C  G S ++S++GE Y FG++A     + 
Sbjct: 576 DGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAI----YS 631

Query: 644 DTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
           D+ +     LV +LKG  +   A+G+ HT  +   G V+  G N  GQCG
Sbjct: 632 DSSS-----LVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCG 676


>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
          Length = 1657

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 622



 Score = 54.0 bits (124), Expect = 7e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLLWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
            protein.
          Length = 4641

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 42/89 (47%)
 Frame = +2

Query: 527  DRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIH 706
            D   R +   C   HSV++ E G+ YTFG    GQLG GD  +R  P LV  L G +   
Sbjct: 899  DCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS-TQ 957

Query: 707  AAVGRHHTLFVTDTGCVYACGDNKSGQCG 793
               G +HT  +   G V+  G    GQ G
Sbjct: 958  VTAGSNHTAVLLMDGQVFTFGSFSKGQLG 986



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 28/84 (33%), Positives = 46/84 (54%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGR 721
           ++ + C  G S ++S++GE Y FG++A     + D+ +     LV +LKG  +   A+G+
Sbjct: 602 VVYTACNNGSSSVISKDGELYMFGKDAI----YSDSSS-----LVTDLKGHFVTQVAMGK 652

Query: 722 HHTLFVTDTGCVYACGDNKSGQCG 793
            HT  +   G V+  G N  GQCG
Sbjct: 653 AHTCVLMKNGEVWTFGVNNKGQCG 676


>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
          Length = 1598

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 460 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 519

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 520 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 563



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 26/70 (37%), Positives = 36/70 (51%)
 Frame = +2

Query: 593 GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGD 772
           GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD G  Y  G+
Sbjct: 1   GEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGE 58

Query: 773 NKSGQCGLGN 802
           N +GQC + N
Sbjct: 59  NSAGQCAVAN 68



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 511 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 569


>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
          Length = 1657

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 622



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
          Length = 1658

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 520 ALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 579

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 580 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 623



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 53  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 110

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 111 GVAYMWGENSAGQCAVAN 128



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 571 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 629



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 33  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 67


>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
          Length = 1237

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%)
 Frame = +2

Query: 572 SVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTG 751
           ++L S   E +T+G+   GQLG GD + R  P  V  L GK +IH   G +H+L +T   
Sbjct: 519 ALLPSLRIEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKS 578

Query: 752 CVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGAEFS 886
            VY+ G N  GQ G  +    + +  +I++ E+    +  G ++S
Sbjct: 579 QVYSWGSNTFGQLGHSDFPTTVPRLAKISS-ENGVWSIAAGRDYS 622



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS+ ++ + + Y++G N  GQLG  D  T +VP L        +   A GR ++LF+ DT
Sbjct: 570 HSLALTAKSQVYSWGSNTFGQLGHSDFPT-TVPRLAKISSENGVWSIAAGRDYSLFLVDT 628



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>BC065375-1|AAH65375.1|  458|Homo sapiens secretion regulating
           guanine nucleotide exchange factor protein.
          Length = 458

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 703
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 704 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I   + + V +  G
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAG 161



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = +2

Query: 602 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 778
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 779 SGQCGLGNT 805
            GQ GLG+T
Sbjct: 78  DGQLGLGHT 86



 Score = 35.5 bits (78), Expect = 0.26
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 727
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 728 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 835
           +  +TD G VY  G NK GQ  L N    +  P +I
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKI 257



 Score = 34.3 bits (75), Expect = 0.60
 Identities = 39/147 (26%), Positives = 57/147 (38%), Gaps = 17/147 (11%)
 Frame = +2

Query: 497 PNLYTFHKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG-----FGDTVTRS 661
           P     H F + +   I SG T  H V  +E G+ +T+GR   GQLG     +       
Sbjct: 254 PQKIEAHCFQNEKVTAIWSGWT--HLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEK 311

Query: 662 VPELVPELKGKNII-----------HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT 808
               +P  +  N +             + G  H L +   G  Y+ G N+ G CG G T 
Sbjct: 312 QDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDG-TE 369

Query: 809 PQILKPTRINT-MEHRXVKVGCGAEFS 886
             +  P  +   +    + VGCGA  S
Sbjct: 370 ANVWAPKPVQALLSSSGLLVGCGAGHS 396


>AJ243951-1|CAB60833.1|  288|Homo sapiens deafness locus associated
           putative guanine nucleotide exchange factor protein.
          Length = 288

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 703
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 704 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I   + + V +  G
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAG 161



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = +2

Query: 602 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 778
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 779 SGQCGLGNT 805
            GQ GLG+T
Sbjct: 78  DGQLGLGHT 86



 Score = 35.5 bits (78), Expect = 0.26
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 727
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 728 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 835
           +  +TD G VY  G NK GQ  L N    +  P +I
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKI 257


>AJ243950-1|CAB60832.1|  458|Homo sapiens deafness locus associated
           putative guanine nucleotide exchange factor protein.
          Length = 458

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
 Frame = +2

Query: 530 RRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP--ELKGKNII 703
           R  R I  G   GHS +V++ G+ +  G N  GQLG G   T  +P   P   L G  I 
Sbjct: 49  RSVRRITGG--GGHSAVVTDGGDLFVCGLNKDGQLGLGH--TEDIPYFTPCKSLFGCPIQ 104

Query: 704 HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
             A G   T+ +T+ G V +CG N  GQ G+ +   + + P  I   + + V +  G
Sbjct: 105 QVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAG 161



 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = +2

Query: 602 YTFGRNACGQLGFGDTVTRSVPELVPEL-KGKNIIHAAVGRHHTLFVTDTGCVYACGDNK 778
           + +G N+ GQLG G      +P+ + +  K +++     G  H+  VTD G ++ CG NK
Sbjct: 18  FAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNK 77

Query: 779 SGQCGLGNT 805
            GQ GLG+T
Sbjct: 78  DGQLGLGHT 86



 Score = 35.5 bits (78), Expect = 0.26
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRN--ACGQ-LGFGDTV----TRSVPELVPELKGKNIIHAAVGRHH 727
           H+V  +  G  + +G    +CG+ L  G T+    T   P  V  L+    +    G  H
Sbjct: 164 HAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDH 223

Query: 728 TLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRI 835
           +  +TD G VY  G NK GQ  L N    +  P +I
Sbjct: 224 SASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKI 257



 Score = 34.3 bits (75), Expect = 0.60
 Identities = 39/147 (26%), Positives = 57/147 (38%), Gaps = 17/147 (11%)
 Frame = +2

Query: 497 PNLYTFHKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG-----FGDTVTRS 661
           P     H F + +   I SG T  H V  +E G+ +T+GR   GQLG     +       
Sbjct: 254 PQKIEAHCFQNEKVTAIWSGWT--HLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEK 311

Query: 662 VPELVPELKGKNII-----------HAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTT 808
               +P  +  N +             + G  H L +   G  Y+ G N+ G CG G T 
Sbjct: 312 QDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDG-TE 369

Query: 809 PQILKPTRINT-MEHRXVKVGCGAEFS 886
             +  P  +   +    + VGCGA  S
Sbjct: 370 ANVWAPKPVQALLSSSGLLVGCGAGHS 396


>AK092403-1|BAC03879.1|  184|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35084 fis, clone PLACE6005482. ).
          Length = 184

 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFG-DTVTRSVPELVPELKGKNIIHAAV 715
           ++I   C   HS+ +S++ + +++G+N+ GQLG G +  +++ P+ V  L+G  +   A 
Sbjct: 7   KIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAA 66

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL-GNTTP-QILKPTRINTMEH-RXVKVGCG 874
           G  H+  ++  G  +  G N +GQ  L G   P Q  KP  +  +++   V + CG
Sbjct: 67  GGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCG 122



 Score = 54.8 bits (126), Expect = 4e-07
 Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQL---GFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFV 739
           HS  +S  G ++ +G N+ GQL   G    V  + P  V  LK   +++ + G  HT  +
Sbjct: 70  HSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 129

Query: 740 TDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           T  G V+  GDN+SGQ G  + TP+   P  +  ++    ++ CG
Sbjct: 130 TQDGKVFTFGDNRSGQLGY-SPTPEKRGPQLVERIDGLVSQIDCG 173



 Score = 43.2 bits (97), Expect = 0.001
 Identities = 16/50 (32%), Positives = 30/50 (60%)
 Frame = +2

Query: 542 LIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG 691
           ++   C   H+ +++++G+ +TFG N  GQLG+  T  +  P+LV  + G
Sbjct: 116 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDG 165


>BC113705-1|AAI13706.1|  692|Homo sapiens NIMA (never in mitosis
           gene a)- related kinase 8 protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 536 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 715
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL 796
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 737 VTDTGCVYACGDNKSGQCGLG 799
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRIN-TMEHRXVKVGC 871
             VY+ G    G+ G  +    + +P +++ T  +    V C
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673



 Score = 36.7 bits (81), Expect = 0.11
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT-MEHRXVKV 865
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT +   + +  V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 866 GCGA 877
            CGA
Sbjct: 449 ACGA 452


>BC112240-1|AAI12241.1|  692|Homo sapiens NIMA-related kinase 8
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 536 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 715
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL 796
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 737 VTDTGCVYACGDNKSGQCGLG 799
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRIN-TMEHRXVKVGC 871
             VY+ G    G+ G  +    + +P +++ T  +    V C
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673



 Score = 36.7 bits (81), Expect = 0.11
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT-MEHRXVKV 865
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT +   + +  V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 866 GCGA 877
            CGA
Sbjct: 449 ACGA 452


>AY267371-1|AAP04006.1|  692|Homo sapiens NIMA-family kinase NEK8
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 536 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 715
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL 796
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 737 VTDTGCVYACGDNKSGQCGLG 799
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRIN-TMEHRXVKVGC 871
             VY+ G    G+ G  +    + +P +++ T  +    V C
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673



 Score = 36.7 bits (81), Expect = 0.11
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT-MEHRXVKV 865
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT +   + +  V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 866 GCGA 877
            CGA
Sbjct: 449 ACGA 452


>AY242354-1|AAO88243.1|  692|Homo sapiens NIMA-related kinase 12a
           protein.
          Length = 692

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 42/87 (48%)
 Frame = +2

Query: 536 YRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 715
           Y ++   C A H + +S E E + +GR   G+LG G   + S P+ VP   G+       
Sbjct: 443 YEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVC 502

Query: 716 GRHHTLFVTDTGCVYACGDNKSGQCGL 796
           G   ++ +T  G   ACG N+  + GL
Sbjct: 503 GIDSSMILTVPGQALACGSNRFNKLGL 529



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF 736
           C    +  +++ G   TFG  + G LG G     S P +V  L G  ++  A G  H L 
Sbjct: 398 CGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLA 457

Query: 737 VTDTGCVYACGDNKSGQCGLG 799
           ++    ++A G   SG+ GLG
Sbjct: 458 LSTERELFAWGRGDSGRLGLG 478



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           HS  V+  G+ YTFG N  GQLG         P  V  L+G  +   A G   T+ +   
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE 631

Query: 749 GCVYACGDNKSGQCGLGNTTPQILKPTRIN-TMEHRXVKVGC 871
             VY+ G    G+ G  +    + +P +++ T  +    V C
Sbjct: 632 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673



 Score = 36.7 bits (81), Expect = 0.11
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +2

Query: 689 GKNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINT-MEHRXVKV 865
           G  I H A G   T  +TD G +   G   +G  G G+ T  I +PT +   + +  V+V
Sbjct: 390 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT-DISQPTIVEALLGYEMVQV 448

Query: 866 GCGA 877
            CGA
Sbjct: 449 ACGA 452


>AK023024-1|BAB14362.1|  396|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
           X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
          Length = 396

 Score = 54.0 bits (124), Expect = 7e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLLWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>AB053306-1|BAB69015.1|  396|Homo sapiens ALS2 protein.
          Length = 396

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDT 748
           H VL++E+GE Y+FG     + G  + +  S P L   L G+ +I  A G  H+  VTD 
Sbjct: 52  HGVLLTEDGEVYSFG-TLPWRSGPVE-ICPSSPILENALVGQYVITVATGSFHSGAVTDN 109

Query: 749 GCVYACGDNKSGQCGLGN 802
           G  Y  G+N +GQC + N
Sbjct: 110 GVAYMWGENSAGQCAVAN 127



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 665 PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           PE +P   GK ++ AA+G  H + +T+ G VY+ G
Sbjct: 32  PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFG 66


>BC040695-1|AAH40695.1|  358|Homo sapiens WBSCR16 protein protein.
          Length = 358

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 706
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 707 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 802
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = +2

Query: 515 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 691
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 692 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKP 826
            N+I  A      L V+  G ++  G+++  Q      + Q+  P
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVP 327


>BC032712-1|AAH32712.1|  454|Homo sapiens WBSCR16 protein protein.
          Length = 454

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 706
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 707 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 802
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = +2

Query: 515 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 691
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 692 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKP 826
            N+I  A      L V+  G ++  G+++  Q      + Q+  P
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVP 327


>BC019008-1|AAH19008.1|  464|Homo sapiens Williams-Beuren syndrome
           chromosome region 16 protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 706
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 707 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 802
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = +2

Query: 515 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 691
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 692 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKP 826
            N+I  A      L V+  G ++  G+++  Q      + Q+  P
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVP 327


>BC007823-1|AAH07823.1|  464|Homo sapiens Williams-Beuren syndrome
           chromosome region 16 protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 706
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 707 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 802
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = +2

Query: 515 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 691
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 692 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKP 826
            N+I  A      L V+  G ++  G+++  Q      + Q+  P
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVP 327


>AF410455-1|AAM62304.1|  464|Homo sapiens RCC1-like G exchanging
           factor-like protein protein.
          Length = 464

 Score = 52.0 bits (119), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
 Frame = +2

Query: 539 RLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG--FGDTVTRSVPELVPELKGKN--IIH 706
           R++   C   HS+++++    ++ G N+ GQ G    +    S    V  ++  +  ++ 
Sbjct: 175 RVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQ 234

Query: 707 AAVGRHHTLFVTDTGCVYACGDNKSGQCGLGN 802
            A G+ H+LF+TD G VY+CG    GQ GLG+
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGH 266



 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = +2

Query: 515 HKFTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKG 691
           H+  D   +++   C   HS+ ++++GE Y+ G  A GQ G G   +T S  +L  +L G
Sbjct: 223 HRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAG 282

Query: 692 KNIIHAAVGRHHTLFVTDTGCVYACGDNKSGQCGLGNTTPQILKP 826
            N+I  A      L V+  G ++  G+++  Q      + Q+  P
Sbjct: 283 VNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVP 327


>X12654-1|CAA31182.1|  421|Homo sapiens protein ( Human mRNA for
           cell cycle gene RCC1. ).
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>X06130-1|CAA29496.1|  421|Homo sapiens protein ( Human mRNA for
           cell cycle gene RCC1. ).
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>D00591-1|BAA00469.1|  421|Homo sapiens RCC1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>CR407693-1|CAG28621.1|  421|Homo sapiens CHC1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>BC069198-1|AAH69198.1|  452|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 452

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 278 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 337

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 338 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 385



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 109 HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 165

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 166 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 211



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 336 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 393

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 394 DGRVFAWGMGTNYQLGTG 411



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 63  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 120

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 121 SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 158


>BC036903-1|AAH36903.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>BC010067-1|AAH10067.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>BC007300-1|AAH07300.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>AL513497-2|CAI22287.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>AF498924-1|AAM21072.1|  421|Homo sapiens regulator of chromosome
           condensation 1 protein.
          Length = 421

 Score = 51.2 bits (117), Expect = 5e-06
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +2

Query: 557 CTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKG--KNIIHAAVGRHHT 730
           C A  +  +S EG  Y FG +   QLG   T +  +P+ +   K   K+ +  + G+HHT
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHT 306

Query: 731 LFVTDTGCVYACGDNKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCGA 877
           + +   G  Y+ G  + G+ GLG    +   PT I+ +      V CGA
Sbjct: 307 VCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLP-AVSSVACGA 354



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVP---ELKGKNIIHAAVGRHHTLFV 739
           H+V +S+ G+ Y+FG N  G LG   +V  S  E+VP   EL+ K ++  + G  HT  +
Sbjct: 78  HTVCLSKSGQVYSFGCNDEGALGRDTSVEGS--EMVPGKVELQEK-VVQVSAGDSHTAAL 134

Query: 740 TDTGCVYACGD--NKSGQCGLGNTTPQILKPTRINTMEHRXVKVGCG 874
           TD G V+  G   + +G  GL     + + P ++  ++   VKV  G
Sbjct: 135 TDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ-LDVPVVKVASG 180



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +2

Query: 569 HSVLVSEEGEAYTFGRNACGQLGFGD-TVTRSVPELVPELKGKNIIHAAVGRHHTLFVTD 745
           H+V +  EG+AY+ GR   G+LG G+    +S+P L+  L    +   A G      VT 
Sbjct: 305 HTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTK 362

Query: 746 TGCVYACGDNKSGQCGLG 799
            G V+A G   + Q G G
Sbjct: 363 DGRVFAWGMGTNYQLGTG 380



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +2

Query: 584 SEEGEAYTFGRNACGQLGFGDTVT-RSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVY 760
           +E G   T G+   GQLG G+ V  R  P LV     ++++ A  G  HT+ ++ +G VY
Sbjct: 32  TEPGLVLTLGQGDVGQLGLGENVMERKKPALVSI--PEDVVQAEAGGMHTVCLSKSGQVY 89

Query: 761 ACGDNKSGQCGLGNTTP-QILKPTRINTMEHRXVKVGCG 874
           + G N  G  G   +     + P ++  ++ + V+V  G
Sbjct: 90  SFGCNDEGALGRDTSVEGSEMVPGKVE-LQEKVVQVSAG 127


>AY650032-1|AAV66578.1|  117|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 2 protein.
          Length = 117

 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
 Frame = +2

Query: 608 FGRNACGQLGFGDTVTRSV--PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 781
           +G  + GQLG G      V  P        K +     G  HT+FV D G VY CG N  
Sbjct: 4   WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63

Query: 782 GQCG--LGNTTPQILKPTRINTM 844
           GQ G       P+ILK  +I+ +
Sbjct: 64  GQLGHEKSRKKPEILKVCQISRL 86



 Score = 34.7 bits (76), Expect = 0.45
 Identities = 20/52 (38%), Positives = 29/52 (55%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELV 676
           F ++R R +  GC   H+V V ++G  YT G N  GQL  G   +R  PE++
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQL--GHEKSRKKPEIL 78


>BC113826-1|AAI13827.1|  244|Homo sapiens RCCD1 protein protein.
          Length = 244

 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 26/69 (37%), Positives = 37/69 (53%)
 Frame = +2

Query: 590 EGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACG 769
           E E + F R+  GQLG G       P L+  L+G  +   A G  H++ V++TG +Y  G
Sbjct: 45  ELELHRF-RDPHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWG 103

Query: 770 DNKSGQCGL 796
            N+SGQ  L
Sbjct: 104 WNESGQLAL 112



 Score = 36.7 bits (81), Expect = 0.11
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +2

Query: 545 IVSGCTAGHSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAV 715
           + + C + H+ +V+  GE YT+G    GQLG  DT +   P  V     K +   AV
Sbjct: 171 VKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAV 227



 Score = 32.7 bits (71), Expect = 1.8
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 10/54 (18%)
 Frame = +2

Query: 542 LIVSGCTAG--HSVLVSEEGEAYTFGRNACGQLGF--------GDTVTRSVPEL 673
           L+++   AG  HSV VSE G+ Y +G N  GQL          G+TV R   EL
Sbjct: 78  LVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATEL 131


>AY650034-1|AAV66580.1|  110|Homo sapiens HECT and RCC1 containing
           protein 4 isoform 4 protein.
          Length = 110

 Score = 41.1 bits (92), Expect = 0.005
 Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
 Frame = +2

Query: 608 FGRNACGQLGFGDTVTRSV--PELVPELKGKNIIHAAVGRHHTLFVTDTGCVYACGDNKS 781
           +G  + GQLG G      V  P        K +     G  HT+FV D G VY CG N  
Sbjct: 4   WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63

Query: 782 GQCG 793
           GQ G
Sbjct: 64  GQLG 67



 Score = 33.9 bits (74), Expect = 0.79
 Identities = 17/39 (43%), Positives = 23/39 (58%)
 Frame = +2

Query: 521 FTDRRYRLIVSGCTAGHSVLVSEEGEAYTFGRNACGQLG 637
           F ++R R +  GC   H+V V ++G  YT G N  GQLG
Sbjct: 31  FINKRVRDV--GCGLRHTVFVLDDGTVYTCGCNDLGQLG 67


>AF225404-1|AAO27482.1|  259|Homo sapiens HERC2 protein.
          Length = 259

 Score = 41.1 bits (92), Expect = 0.005
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 593 GEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHTLF-VTDTGCVYACG 769
           G  Y +G N  GQLG  +     VP     L     +   +G   TLF VT  G +YA G
Sbjct: 127 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQ-LIGGEQTLFAVTADGKLYATG 185

Query: 770 DNKSGQCGLGNTTPQILKPTRINTMEHRXVK 862
               G+ G+G  T  +  PT + +++H  +K
Sbjct: 186 YGAGGRLGIGG-TESVSTPTLLESIQHVFIK 215


>BC067293-1|AAH67293.1|  580|Homo sapiens F-box protein 24 protein.
          Length = 580

 Score = 31.9 bits (69), Expect = 3.2
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = +2

Query: 557 CTAG--HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHT 730
           C  G  H  LV E G  +  G N  GQLG GD + R  P  V  L  +  I    G +H+
Sbjct: 362 CALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHS 419

Query: 731 LFVTDT 748
           L ++ +
Sbjct: 420 LVLSQS 425


>AC069281-1|AAP21863.1|  580|Homo sapiens unknown protein.
          Length = 580

 Score = 31.9 bits (69), Expect = 3.2
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = +2

Query: 557 CTAG--HSVLVSEEGEAYTFGRNACGQLGFGDTVTRSVPELVPELKGKNIIHAAVGRHHT 730
           C  G  H  LV E G  +  G N  GQLG GD + R  P  V  L  +  I    G +H+
Sbjct: 362 CALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYL--QRPITLWCGLNHS 419

Query: 731 LFVTDT 748
           L ++ +
Sbjct: 420 LVLSQS 425


>BC103891-1|AAI03892.2|  428|Homo sapiens POM121L1 protein protein.
          Length = 428

 Score = 30.3 bits (65), Expect = 9.7
 Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = -3

Query: 818 RSEVLY---SQVRTDRSCCPRKRIHSQCRSQTMYGVSQLRRG*CSCPSTLVLARERSVSP 648
           RSE+ Y   SQ     SC  R  I S   S       + RRG  S    L L+  ++VS 
Sbjct: 99  RSEIRYNQTSQTSWTSSCTNRNAISSSYSSTGGLPGLKRRRGPASSHCQLTLSSSKTVSE 158

Query: 647 CLRSRVD--HTHCDQTCRLLPLRT 582
                V   HT C++   + P +T
Sbjct: 159 DRPQAVSSGHTQCEKVAEIAPGQT 182


>AL162741-4|CAI23246.1|  255|Homo sapiens tumor necrosis factor
           receptor superfamily, member 18 protein.
          Length = 255

 Score = 30.3 bits (65), Expect = 9.7
 Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
 Frame = +1

Query: 550 QWVHCRTFSFGVRRGRSLHVWSQCVWSTRLRRHGDTERSRASTRVEGQEHHPRR--SWET 723
           Q + C + +F          W+ C W  R RR   T  + +S R  G     RR   WET
Sbjct: 111 QCIDCASGTFSGGHEGHCKPWTDCCW--RCRRRPKTPEAASSPRKSGASDRQRRRGGWET 168


>AF241229-1|AAF63506.1|  255|Homo sapiens GITR-D protein.
          Length = 255

 Score = 30.3 bits (65), Expect = 9.7
 Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
 Frame = +1

Query: 550 QWVHCRTFSFGVRRGRSLHVWSQCVWSTRLRRHGDTERSRASTRVEGQEHHPRR--SWET 723
           Q + C + +F          W+ C W  R RR   T  + +S R  G     RR   WET
Sbjct: 111 QCIDCASGTFSGGHEGHCKPWTDCCW--RCRRRPKTPEAASSPRKSGASDRQRRRGGWET 168


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,164,573
Number of Sequences: 237096
Number of extensions: 2946525
Number of successful extensions: 7397
Number of sequences better than 10.0: 104
Number of HSP's better than 10.0 without gapping: 6362
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7198
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11326166088
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -