Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP01_F_H15
(898 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 122 1e-27
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 122 2e-27
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 122 2e-27
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 122 2e-27
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 122 2e-27
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 122 2e-27
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 122 2e-27
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 122 2e-27
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 122 2e-27
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 121 3e-27
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 121 3e-27
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 121 3e-27
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 121 4e-27
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 120 5e-27
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 120 5e-27
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 120 7e-27
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 117 5e-26
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 116 9e-26
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 116 1e-25
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 116 1e-25
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 115 2e-25
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 115 2e-25
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 115 2e-25
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 115 2e-25
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 115 2e-25
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 115 2e-25
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 115 3e-25
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 115 3e-25
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 115 3e-25
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 115 3e-25
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 115 3e-25
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 115 3e-25
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 115 3e-25
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 114 4e-25
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 113 8e-25
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 113 8e-25
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 113 8e-25
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 113 8e-25
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 113 8e-25
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 113 8e-25
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 113 8e-25
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 113 8e-25
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 113 8e-25
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 113 8e-25
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 113 8e-25
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 110 6e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 109 1e-23
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 109 2e-23
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 109 2e-23
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 109 2e-23
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 109 2e-23
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 109 2e-23
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 109 2e-23
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 107 7e-23
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 107 7e-23
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 107 7e-23
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 107 7e-23
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 107 7e-23
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 106 1e-22
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 103 9e-22
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 103 1e-21
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 103 1e-21
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 103 1e-21
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 103 1e-21
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 102 2e-21
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 102 2e-21
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 102 2e-21
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 102 2e-21
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 102 2e-21
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 102 2e-21
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 102 2e-21
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 102 2e-21
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 102 2e-21
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 98 3e-20
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 71 7e-14
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 42 0.002
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 36 0.15
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 33 1.9
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 31 7.5
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 122 bits (295), Expect = 1e-27
Identities = 57/122 (46%), Positives = 81/122 (66%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P+ K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 38.3 bits (85), Expect = 0.037
Identities = 17/40 (42%), Positives = 25/40 (62%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 122 bits (293), Expect = 2e-27
Identities = 57/122 (46%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G +
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 724 ED 729
D
Sbjct: 122 LD 123
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 131 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 170
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 127
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 145 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 181
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 59/118 (50%), Positives = 82/118 (69%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 121 bits (291), Expect = 4e-27
Identities = 56/120 (46%), Positives = 79/120 (65%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+ +
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 550 TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G + D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Score = 44.0 bits (99), Expect = 8e-04
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 120 bits (290), Expect = 5e-27
Identities = 59/118 (50%), Positives = 81/118 (68%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 35.5 bits (78), Expect = 0.26
Identities = 17/31 (54%), Positives = 18/31 (58%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
D W ME GLAKSIGVSNFN Q+
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 120 bits (290), Expect = 5e-27
Identities = 56/122 (45%), Positives = 80/122 (65%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 543
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 544 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYT 723
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P + G +
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Query: 724 ED 729
D
Sbjct: 125 LD 126
Score = 44.4 bits (100), Expect = 6e-04
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +2
Query: 749 SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+ + +D W ME+LV +GL K+IG+SNFN Q+ +K
Sbjct: 134 SDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSK 173
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 120 bits (289), Expect = 7e-27
Identities = 59/118 (50%), Positives = 81/118 (68%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 35.5 bits (78), Expect = 0.26
Identities = 17/31 (54%), Positives = 18/31 (58%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
D W ME GLAKSIGVSNFN Q+
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 117 bits (282), Expect = 5e-26
Identities = 58/118 (49%), Positives = 81/118 (68%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLWST HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 116 bits (280), Expect = 9e-26
Identities = 57/125 (45%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ GY ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 116 bits (279), Expect = 1e-25
Identities = 60/139 (43%), Positives = 87/139 (62%), Gaps = 4/139 (2%)
Frame = +1
Query: 346 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 516
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 517 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 696
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 697 LKE-GNSSYTEDIISDPIL 750
+K+ G +D + IL
Sbjct: 125 MKQPGKELLPKDASGEIIL 143
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 116 bits (279), Expect = 1e-25
Identities = 60/139 (43%), Positives = 87/139 (62%), Gaps = 4/139 (2%)
Frame = +1
Query: 346 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 516
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 517 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 696
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 697 LKE-GNSSYTEDIISDPIL 750
+K+ G +D + IL
Sbjct: 125 MKQPGKELLPKDASGEIIL 143
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 715 SYTED 729
+D
Sbjct: 141 VIPKD 145
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 182
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 115 bits (277), Expect = 2e-25
Identities = 56/125 (44%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
+IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 715 SYTED 729
+D
Sbjct: 126 PLPKD 130
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 137 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 177
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 34.7 bits (76), Expect = 0.46
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNK 179
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 115 bits (276), Expect = 3e-25
Identities = 55/125 (44%), Positives = 83/125 (66%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 715 SYTED 729
+D
Sbjct: 128 PLPKD 132
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 139 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +1
Query: 346 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 516
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 517 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 696
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 697 LK 702
+K
Sbjct: 125 MK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +1
Query: 346 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 516
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 517 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 696
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 697 LK 702
+K
Sbjct: 125 MK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +1
Query: 346 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 516
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 517 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 696
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 697 LK 702
+K
Sbjct: 125 MK 126
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 54/118 (45%), Positives = 78/118 (66%), Gaps = 3/118 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G A+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEG 708
KI DG+V+R+++F KLW HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPG 125
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 143 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 113 bits (272), Expect = 8e-25
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 715 SYTED 729
+D
Sbjct: 128 VIPKD 132
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 110 bits (265), Expect = 6e-24
Identities = 54/125 (43%), Positives = 80/125 (64%), Gaps = 3/125 (2%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 534
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 535 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
KI DG+V+R+++F KLW HR +L A SL +L L++ DL+LIH P+S+K G
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 715 SYTED 729
+D
Sbjct: 125 VIPKD 129
Score = 31.5 bits (68), Expect = 4.3
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E LAKSIGVSNFN + + K
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNK 176
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 109 bits (263), Expect = 1e-23
Identities = 54/127 (42%), Positives = 81/127 (63%), Gaps = 3/127 (2%)
Frame = +1
Query: 343 SVKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKL 513
S + ++KL DG FMP++ GT++ + E V+ AID+GYR ID+AY + NE+
Sbjct: 2 SFNRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 514 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 693
IG+AI+ KI +GTV+R ++F K+W TF R +LV+ +SL L L + DL+L H P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 694 SLKEGNS 714
L+ G S
Sbjct: 122 PLQPGRS 128
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/46 (50%), Positives = 31/46 (67%)
Frame = +2
Query: 731 SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+ R K
Sbjct: 138 SNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/46 (50%), Positives = 31/46 (67%)
Frame = +2
Query: 731 SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+ R K
Sbjct: 138 SNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/46 (50%), Positives = 31/46 (67%)
Frame = +2
Query: 731 SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+ R K
Sbjct: 138 SNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/46 (50%), Positives = 31/46 (67%)
Frame = +2
Query: 731 SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+ R K
Sbjct: 138 SNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 702
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
Score = 52.0 bits (119), Expect = 3e-06
Identities = 23/46 (50%), Positives = 31/46 (67%)
Frame = +2
Query: 731 SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+ R K
Sbjct: 138 SNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 107 bits (256), Expect = 7e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ + +D
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 107 bits (256), Expect = 7e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ + +D
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 107 bits (256), Expect = 7e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ + +D
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 107 bits (256), Expect = 7e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ + +D
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 107 bits (256), Expect = 7e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ + +D
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 106 bits (254), Expect = 1e-22
Identities = 51/117 (43%), Positives = 77/117 (65%), Gaps = 3/117 (2%)
Frame = +1
Query: 388 MPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVR 558
MPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++KI DG+V+
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 559 RDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G + +D
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKD 117
Score = 35.1 bits (77), Expect = 0.35
Identities = 18/41 (43%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+ D W ME GLAKSIGVSNFN Q+ K
Sbjct: 124 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 164
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 103 bits (247), Expect = 9e-22
Identities = 50/114 (43%), Positives = 68/114 (59%)
Frame = +1
Query: 388 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 567
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 568 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
LFI KLW TF LV A +L D L + D++LIH P K G+ + +D
Sbjct: 73 LFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKD 126
Score = 43.6 bits (98), Expect = 0.001
Identities = 18/36 (50%), Positives = 26/36 (72%)
Frame = +2
Query: 761 YMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
++DAW ME+LV +GL K++GVSNF+ QI + K
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 103 bits (246), Expect = 1e-21
Identities = 54/126 (42%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 531
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 532 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 711
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 712 SSYTED 729
Y D
Sbjct: 130 EIYPRD 135
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
Y + + W ME GL KS+GVSNFN Q+ K
Sbjct: 142 YHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 182
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 103 bits (246), Expect = 1e-21
Identities = 54/126 (42%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 531
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 532 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 711
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 712 SSYTED 729
Y D
Sbjct: 130 EIYPRD 135
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
Y + + W ME GL KS+GVSNFN Q+ K
Sbjct: 142 YHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 182
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 103 bits (246), Expect = 1e-21
Identities = 54/126 (42%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 531
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 532 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 711
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 712 SSYTED 729
Y D
Sbjct: 130 EIYPRD 135
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
Y + + W ME GL KS+GVSNFN Q+ K
Sbjct: 142 YHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 182
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 103 bits (246), Expect = 1e-21
Identities = 54/126 (42%), Positives = 76/126 (60%), Gaps = 4/126 (3%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 531
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 532 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 711
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 712 SSYTED 729
Y D
Sbjct: 130 EIYPRD 135
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
Y + + W ME GL KS+GVSNFN Q+ K
Sbjct: 142 YHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 182
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 102 bits (244), Expect = 2e-21
Identities = 53/121 (43%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 370 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 549
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 550 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTE 726
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 727 D 729
+
Sbjct: 128 N 128
Score = 43.6 bits (98), Expect = 0.001
Identities = 19/37 (51%), Positives = 25/37 (67%)
Frame = +2
Query: 740 IQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +1
Query: 394 VIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRD 564
V+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++KI DG+V+R+
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 565 ELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSYTED 729
++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G +D
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 115
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 111 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 162
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 71.3 bits (167), Expect(2) = 7e-14
Identities = 32/72 (44%), Positives = 48/72 (66%)
Frame = +1
Query: 514 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 693
+G AI++KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 86
Query: 694 SLKEGNSSYTED 729
S+K G +D
Sbjct: 87 SVKPGEEVIPKD 98
Score = 36.3 bits (80), Expect = 0.15
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 716 LIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
+IPK + I + D W +E GLAKSIGVSNFN Q+ K
Sbjct: 94 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Score = 26.2 bits (55), Expect(2) = 7e-14
Identities = 10/16 (62%), Positives = 12/16 (75%)
Frame = +1
Query: 364 LKLRDGTFMPVIALGT 411
+KL DG FMPV+ GT
Sbjct: 6 VKLNDGHFMPVLGFGT 21
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 42.3 bits (95), Expect = 0.002
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +1
Query: 586 LWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 714
+W TF R +LV+ +SL L L + DL+L H P+ L+ G S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 36.3 bits (80), Expect = 0.15
Identities = 18/37 (48%), Positives = 19/37 (51%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
D W ME GLAKSIGVSNFN Q+ K
Sbjct: 20 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 56
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 746 YSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQIRRFWTK 868
Y + + W ME GL KS+GVSNFN Q+ K
Sbjct: 20 YHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 60
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 30.7 bits (66), Expect = 7.5
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
Frame = -2
Query: 855 LLIWVE---LKLLTPMLLAKPFATRSSMPNQASM*SNSEYWITDDIFGIRTV 709
+L+WV+ L LL P LLA+ A RS + ++ S+Y +T+ G+R V
Sbjct: 1 MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPV 52
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 128,003,336
Number of Sequences: 237096
Number of extensions: 2851854
Number of successful extensions: 8380
Number of sequences better than 10.0: 94
Number of HSP's better than 10.0 without gapping: 7653
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8319
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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