Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP01_F_E22
(883 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 109 1e-22
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 105 1e-21
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 103 5e-21
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 102 1e-20
UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor... 97 4e-19
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 97 4e-19
UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ... 92 1e-17
UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1... 89 2e-16
UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;... 87 6e-16
UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling... 87 6e-16
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 87 6e-16
UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor... 87 7e-16
UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;... 86 1e-15
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 84 4e-15
UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;... 81 3e-14
UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster... 76 1e-12
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 75 2e-12
UniRef50_UPI0000D9E331 Cluster: PREDICTED: similar to Suppressor... 71 4e-11
UniRef50_UPI0000DB7AEC Cluster: PREDICTED: similar to Suppressor... 69 1e-10
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 66 8e-10
UniRef50_UPI00015B50BA Cluster: PREDICTED: similar to suppressor... 64 6e-09
UniRef50_Q29LD7 Cluster: GA13535-PA; n=1; Drosophila pseudoobscu... 62 1e-08
UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila pseudoobscu... 62 1e-08
UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 61 3e-08
UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|R... 60 6e-08
UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=3... 60 1e-07
UniRef50_Q91ZA6 Cluster: Suppressor of cytokine signaling 4; n=1... 58 2e-07
UniRef50_O45498 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2... 57 5e-07
UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1... 57 7e-07
UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;... 54 4e-06
UniRef50_Q4H2S6 Cluster: Suppressor of cytokine signaling; n=1; ... 54 6e-06
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 52 1e-05
UniRef50_A7RUJ8 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 51 3e-05
UniRef50_Q4RXL6 Cluster: Chromosome 11 SCAF14979, whole genome s... 51 4e-05
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 51 4e-05
UniRef50_O14543 Cluster: Suppressor of cytokine signaling 3; n=2... 51 4e-05
UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote... 51 4e-05
UniRef50_UPI000069EEDB Cluster: UPI000069EEDB related cluster; n... 50 6e-05
UniRef50_Q90X67 Cluster: Suppressor of cytokine signaling 3; n=1... 50 6e-05
UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1... 49 1e-04
UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;... 49 2e-04
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 49 2e-04
UniRef50_UPI0000D56C32 Cluster: PREDICTED: similar to Suppressor... 48 3e-04
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 48 4e-04
UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91... 47 6e-04
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 47 7e-04
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 46 0.001
UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2... 46 0.001
UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s... 45 0.003
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 44 0.004
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 44 0.007
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 43 0.012
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 42 0.016
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 42 0.021
UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ... 42 0.027
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 42 0.027
UniRef50_Q60UZ3 Cluster: Putative uncharacterized protein CBG197... 42 0.027
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 42 0.027
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 42 0.027
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 41 0.036
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 41 0.036
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 41 0.036
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 41 0.036
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 40 0.063
UniRef50_UPI0000DB734C Cluster: PREDICTED: similar to Suppressor... 40 0.063
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 40 0.063
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 40 0.063
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 40 0.063
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 40 0.063
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 40 0.063
UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73... 40 0.084
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 40 0.084
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 40 0.11
UniRef50_UPI0000F1D282 Cluster: PREDICTED: hypothetical protein;... 39 0.15
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 39 0.15
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 39 0.19
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 38 0.26
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 38 0.26
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 38 0.34
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 38 0.34
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 38 0.34
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 38 0.45
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 37 0.59
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 37 0.59
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 37 0.59
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 37 0.78
UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit... 37 0.78
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 37 0.78
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 37 0.78
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 36 1.4
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 36 1.4
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 36 1.4
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 36 1.4
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 36 1.8
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 36 1.8
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 36 1.8
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 36 1.8
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 36 1.8
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 36 1.8
UniRef50_UPI0000447279 Cluster: PREDICTED: similar to suppressor... 35 2.4
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 35 2.4
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.4
UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole... 35 3.2
UniRef50_Q9UB28 Cluster: Myotactin form B; n=6; cellular organis... 35 3.2
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 35 3.2
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 35 3.2
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 35 3.2
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 35 3.2
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 34 4.2
UniRef50_A4FSF6 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 34 4.2
UniRef50_Q4SZG7 Cluster: Chromosome 18 SCAF11624, whole genome s... 34 5.5
UniRef50_Q239X8 Cluster: Putative uncharacterized protein; n=2; ... 34 5.5
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 34 5.5
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 34 5.5
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 33 7.3
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 33 7.3
UniRef50_UPI000049929A Cluster: protein kinase; n=1; Entamoeba h... 33 9.6
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 33 9.6
UniRef50_UPI000065EF23 Cluster: Homolog of Homo sapiens "KARP-1-... 33 9.6
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 33 9.6
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 33 9.6
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 33 9.6
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 33 9.6
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 33 9.6
UniRef50_Q6CWY2 Cluster: Similarities with sp|P39943 Saccharomyc... 33 9.6
>UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Apis mellifera|Rep: PREDICTED: similar to
Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor
of cytokine signaling 4) (SOCS-4) (Cytokine-inducible
SH2 protein 4) (CIS-4) - Apis mellifera
Length = 358
Score = 109 bits (261), Expect = 1e-22
Identities = 62/150 (41%), Positives = 87/150 (58%), Gaps = 14/150 (9%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N+GWYWG I+ +EA+ L + D FLVRDS D R++L +SF+ G+ LHAR+ H+ G F
Sbjct: 204 NYGWYWGPISGNEADAKLLSEPDGAFLVRDSSDDRYVLTLSFKSSGKLLHARMEHSGGLF 263
Query: 291 SL----DNETFVPA-----YRLSEHCSAVNVKTNLF-----EMPVKLARPLNRFAKLDSL 428
SL ++E F Y +S SAV + PV+L +P++RF ++ SL
Sbjct: 264 SLCNQSESEGFTSVADLIDYSMSFSQSAVFCYSRPKYPGHPSFPVRLTKPVSRFTQVRSL 323
Query: 429 QKICRFVIRQTGSSNTWAKLPLPPNLISYI 518
Q +CRFVIRQ + KLPLP + YI
Sbjct: 324 QYLCRFVIRQNTRLDNIHKLPLPKTIKGYI 353
>UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;
n=2; Euteleostomi|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 519
Score = 105 bits (252), Expect = 1e-21
Identities = 63/148 (42%), Positives = 80/148 (54%), Gaps = 14/148 (9%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG IT EAEE L D FLVRDS D R++L +SFR G+TLH R+ H+NG FS
Sbjct: 367 GWYWGPITRWEAEEKLVNLPDGSFLVRDSSDDRYLLSLSFRSQGKTLHTRIEHSNGRFSF 426
Query: 297 ----DNETFVPAYRLSEH----------CSAVNVKTNLFEMPVKLARPLNRFAKLDSLQK 434
D E L EH C + + PV+L P++RF ++ SLQ
Sbjct: 427 YEQPDVEGHTSIVDLIEHSIKDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQY 486
Query: 435 ICRFVIRQTGSSNTWAKLPLPPNLISYI 518
+CRFVIRQ + KLPLP + Y+
Sbjct: 487 LCRFVIRQYTRIDLIQKLPLPNKMKDYL 514
>UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=27;
Euteleostomi|Rep: Suppressor of cytokine signaling 6 -
Homo sapiens (Human)
Length = 535
Score = 103 bits (248), Expect = 5e-21
Identities = 63/148 (42%), Positives = 80/148 (54%), Gaps = 14/148 (9%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG IT EAE LA D FLVRDS D R++L +SFR G+TLH R+ H+NG FS
Sbjct: 383 GWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSF 442
Query: 297 ----DNETFVPAYRLSEH----------CSAVNVKTNLFEMPVKLARPLNRFAKLDSLQK 434
D E L EH C + + PV+L P++RF ++ SLQ
Sbjct: 443 YEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQY 502
Query: 435 ICRFVIRQTGSSNTWAKLPLPPNLISYI 518
+CRFVIRQ + KLPLP + Y+
Sbjct: 503 LCRFVIRQYTRIDLIQKLPLPNKMKDYL 530
>UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 391
Score = 102 bits (245), Expect = 1e-20
Identities = 57/143 (39%), Positives = 80/143 (55%), Gaps = 10/143 (6%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL- 296
WYWG ++ EAE L D FLVRDS D R++L +SF+ GRTLH R+ H NG FSL
Sbjct: 244 WYWGPMSQDEAEGKLDDADDGSFLVRDSSDDRYLLTLSFKSNGRTLHTRIEHRNGLFSLN 303
Query: 297 DNETFVPAYRLSEHC---------SAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFV 449
D+E L E+ +N T + P +L + ++R++++ SLQ +CRFV
Sbjct: 304 DSEGHASVIELIENAVKESQGGVFGYMNDSTGIQNFPARLTQWVSRYSEVKSLQYLCRFV 363
Query: 450 IRQTGSSNTWAKLPLPPNLISYI 518
IR+T + LPLP + YI
Sbjct: 364 IRETYPRHHIRHLPLPKKINEYI 386
>UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Suppressor of cytokine signaling 6 (SOCS-6)
(Suppressor of cytokine signaling 4) (SOCS-4)
(Cytokine-inducible SH2 protein 4) (CIS-4) - Tribolium
castaneum
Length = 297
Score = 97.5 bits (232), Expect = 4e-19
Identities = 54/146 (36%), Positives = 86/146 (58%), Gaps = 13/146 (8%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG + ++EAEE L + D FLVRDS + ++ +SFR VG+T+HAR+ ++ G ++L
Sbjct: 147 WYWGPMPTAEAEEKLQFKPDGTFLVRDSGSTNYLFSISFRSVGKTMHARIEYSRGRYNLC 206
Query: 300 N----------ETFVPAYRLSE---HCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKIC 440
E A + SE +C + + +E PV+L +P++R+ ++ SL+ +C
Sbjct: 207 GTYAEGFTTVTELIQDAMKTSENGIYCYSRRGE-QAYEFPVRLTKPISRYEEVRSLKHLC 265
Query: 441 RFVIRQTGSSNTWAKLPLPPNLISYI 518
+FVIRQ + N KLPLP L Y+
Sbjct: 266 KFVIRQYTNMNDIPKLPLPTVLHGYL 291
>UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 169
Score = 97.5 bits (232), Expect = 4e-19
Identities = 59/144 (40%), Positives = 76/144 (52%), Gaps = 12/144 (8%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N GWYWG ++S EAE+ L Q D FLVRDS + H+L VSFR G T H RL++ G F
Sbjct: 26 NCGWYWGPMSSKEAEKELYNQPDGCFLVRDSENDYHLLSVSFRSKGATCHTRLIYNKGKF 85
Query: 291 SL--DNETFVPAYRLSEH----------CSAVNVKTNLFEMPVKLARPLNRFAKLDSLQK 434
S D AY L H C++ N PV+L P++RF + LQ
Sbjct: 86 SFFQDEMGKDSAYELIMHAMEASQDGILCNSRGHNRNTICYPVRLQVPISRFNTVPPLQF 145
Query: 435 ICRFVIRQTGSSNTWAKLPLPPNL 506
+CRFVIRQ + +LPLP +
Sbjct: 146 LCRFVIRQNIRCDQLDQLPLPKQI 169
>UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 406
Score = 92.3 bits (219), Expect = 1e-17
Identities = 56/150 (37%), Positives = 81/150 (54%), Gaps = 15/150 (10%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG +T SEAE+ L + FLVRDS D R++L +SFR GRTLH R+ H++G FS
Sbjct: 253 GWYWGPLTRSEAEDKLNETPNGSFLVRDSSDERYLLSLSFRSFGRTLHTRIEHSSGNFSF 312
Query: 297 DNETFVPAY-----------RLSEH----CSAVNVKTNLFEMPVKLARPLNRFAKLDSLQ 431
+ +Y R S+ C + PV+L P++R +++ +LQ
Sbjct: 313 YENNRMQSYDSVVDLIMDSVRDSQEAGIFCYSRTRDPLATTYPVRLIHPVSRLSQVRTLQ 372
Query: 432 KICRFVIRQTGSSNTWAKLPLPPNLISYIS 521
+CRFVIRQ + LPLP + Y++
Sbjct: 373 YLCRFVIRQYTRIDHIESLPLPNPVKGYLN 402
>UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=15;
Euteleostomi|Rep: Suppressor of cytokine signaling 7 -
Homo sapiens (Human)
Length = 581
Score = 88.6 bits (210), Expect = 2e-16
Identities = 61/150 (40%), Positives = 76/150 (50%), Gaps = 16/150 (10%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG + +AE L G+ D FLVRDS D R+IL +SFR G T H R+ H G FSL
Sbjct: 399 GWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSL 458
Query: 297 -------DNETFVPAYRLSEHCSAVNVKTNLF---------EMPVKLARPLNRFAKLDSL 428
D V + + N K F PV+L P++RF+ + SL
Sbjct: 459 WCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSL 518
Query: 429 QKICRFVIRQTGSSNTWAKLPLPPNLISYI 518
Q +CRF IRQ + LPLP LISYI
Sbjct: 519 QHLCRFRIRQLVRIDHIPDLPLPKPLISYI 548
>UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to CG8146-PA
- Nasonia vitripennis
Length = 944
Score = 87.0 bits (206), Expect = 6e-16
Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 13/150 (8%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
++GWYWG I+ AE++L+ + D F+VRDS D +I +SFR H R+ H G F
Sbjct: 756 DYGWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRHVRIEHDQGNF 815
Query: 291 SLDN-------------ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQ 431
S + E V R + ++ + L M V+L P++RF ++ SLQ
Sbjct: 816 SFGSCTKFKSHTIVDFIENAVEHSRSGRYLFFLHRRPVLGPMRVQLLHPVSRFKQVQSLQ 875
Query: 432 KICRFVIRQTGSSNTWAKLPLPPNLISYIS 521
CRFVI + + LPLP LI Y+S
Sbjct: 876 HTCRFVILKMVRKDLIPTLPLPRRLIDYLS 905
>UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling 7
(SOCS-7) (Nck, Ash and phospholipase C gamma-binding
protein) (Nck-associated protein 4) (NAP-4).; n=3;
Deuterostomia|Rep: Suppressor of cytokine signaling 7
(SOCS-7) (Nck, Ash and phospholipase C gamma-binding
protein) (Nck-associated protein 4) (NAP-4). - Gallus
gallus
Length = 153
Score = 87.0 bits (206), Expect = 6e-16
Identities = 57/146 (39%), Positives = 76/146 (52%), Gaps = 12/146 (8%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG + +AE L G+ D FLVRDS D R+IL +SFR G T H R+ H G FSL
Sbjct: 1 GWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSL 60
Query: 297 -------DN-----ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKIC 440
D E A S++ + L PV+L P++RF+ + SLQ +C
Sbjct: 61 WCHPKFEDRCQSVVEFIKRAIMHSKNVTPPPPLQGLPPTPVQLLYPVSRFSNVKSLQHLC 120
Query: 441 RFVIRQTGSSNTWAKLPLPPNLISYI 518
RF IRQ + +LPLP + Y+
Sbjct: 121 RFRIRQLVRIDHIPELPLPNLSLQYL 146
>UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 312
Score = 87.0 bits (206), Expect = 6e-16
Identities = 51/149 (34%), Positives = 77/149 (51%), Gaps = 14/149 (9%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFS 293
+GWYWG +T S A++ LA Q + FLVRDS +H +SFR G TLH R+ + + +S
Sbjct: 160 YGWYWGKLTRSAAQKRLARQDNGTFLVRDSETEKHQFAISFRSSGITLHCRIDYKDKNWS 219
Query: 294 LDNETFVPAYRLSEHCSAVNVKTNLFEM--------------PVKLARPLNRFAKLDSLQ 431
T Y ++K + ++ PV+L++P+NRF ++ +LQ
Sbjct: 220 FSGLTAPTHYATMIELIEDSMKKSELDVIGFGKQTCPLTPPFPVRLSKPINRFFEVATLQ 279
Query: 432 KICRFVIRQTGSSNTWAKLPLPPNLISYI 518
+C+F+IRQ LPLP L YI
Sbjct: 280 HMCKFIIRQRVDIKDIRYLPLPSKLQKYI 308
>UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial; n=1; Apis
mellifera|Rep: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial - Apis
mellifera
Length = 804
Score = 86.6 bits (205), Expect = 7e-16
Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 13/150 (8%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
++GWYWG I+ AE++L+ + D F+VRDS D +I +SFR H R+ H G F
Sbjct: 617 DYGWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRHVRIEHDQGNF 676
Query: 291 SLDN-------------ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQ 431
S + E V R + ++ + L M V+L P++RF ++ SLQ
Sbjct: 677 SFGSCTKFKSHTIVDFIENAVEHSRSGRYLFFLHRRPVLGPMRVQLLHPVSRFKQVQSLQ 736
Query: 432 KICRFVIRQTGSSNTWAKLPLPPNLISYIS 521
CRFVI + + LPLP LI Y+S
Sbjct: 737 HTCRFVILKMVRRDLIPTLPLPRRLIDYLS 766
>UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 720
Score = 86.2 bits (204), Expect = 1e-15
Identities = 59/150 (39%), Positives = 76/150 (50%), Gaps = 16/150 (10%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG + +AE L G+ D FLVRDS D R+IL +SFR G T H R+ H G FSL
Sbjct: 538 GWYWGPMNWEDAEMKLRGKPDGSFLVRDSSDPRYILSLSFRSQGVTHHTRMEHYRGTFSL 597
Query: 297 -------DNETFVPAYRLSEHCSAVNVKTNLF---------EMPVKLARPLNRFAKLDSL 428
D V + + N K F PV+L P++RF+ + SL
Sbjct: 598 WCHPKFEDRCHSVVEFIERAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSL 657
Query: 429 QKICRFVIRQTGSSNTWAKLPLPPNLISYI 518
Q +CRF IRQ + +LPLP LI Y+
Sbjct: 658 QHLCRFCIRQLVRIDHIQELPLPKPLIVYL 687
>UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:
ENSANGP00000031260 - Anopheles gambiae str. PEST
Length = 491
Score = 84.2 bits (199), Expect = 4e-15
Identities = 51/148 (34%), Positives = 75/148 (50%), Gaps = 14/148 (9%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG ITS AE++L+ + D FLVRDS D +I ++F+ G H R+ G FS
Sbjct: 318 GWYWGPITSEGAEKILSNEPDGSFLVRDSSDDHYIFSLTFKLNGTVRHVRIDQYQGSFSF 377
Query: 297 DN-------------ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKI 437
+ E V R + ++ + M V+L +P++RF + SLQ I
Sbjct: 378 GSCAKFKSRTIMEFIENAVEHSRSGRYLFFLHRRPEYGPMRVQLTKPVSRFKHVQSLQHI 437
Query: 438 CRFVIRQT-GSSNTWAKLPLPPNLISYI 518
CRFVI +T + LPLP ++ Y+
Sbjct: 438 CRFVIHKTIKRKDLIQALPLPRRVLDYL 465
>UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8146-PA - Tribolium castaneum
Length = 687
Score = 81.4 bits (192), Expect = 3e-14
Identities = 49/150 (32%), Positives = 76/150 (50%), Gaps = 13/150 (8%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
++GWYWG + S AE++L+ + D F+VRDS D +I ++F+ H R+ H G F
Sbjct: 476 DYGWYWGPLPSEVAEKILSNEPDGSFIVRDSSDDHYIFSLTFKLNNCVRHVRIDHDQGNF 535
Query: 291 S------LDNETFVPAYRLS-EHCSAVNVKTNLFEMP------VKLARPLNRFAKLDSLQ 431
S ++T V + EH + L P V+L P++RF ++ SLQ
Sbjct: 536 SFGSCTKFKSQTIVEFIENAVEHSRSGRYLFFLHRRPVIGPVRVQLLHPVSRFKQVQSLQ 595
Query: 432 KICRFVIRQTGSSNTWAKLPLPPNLISYIS 521
ICRF I + + LPLP +I Y++
Sbjct: 596 HICRFAIHKVVRRDLIPSLPLPRRMIDYLN 625
>UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster|Rep:
CG8146-PA - Drosophila melanogaster (Fruit fly)
Length = 1039
Score = 76.2 bits (179), Expect = 1e-12
Identities = 47/151 (31%), Positives = 75/151 (49%), Gaps = 14/151 (9%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
++GWYWG ++S AE++L+ + D F+VRDS D +I +SF+ H R+ G F
Sbjct: 865 DYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTF 924
Query: 291 SLDN-------------ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQ 431
S + E V R + ++ + M V+L P++RF + SLQ
Sbjct: 925 SFGSYAKFKSQTITEFIEKAVEHSRSGRYLFFLHRRPEHGPMRVQLTNPVSRFKHVQSLQ 984
Query: 432 KICRFVI-RQTGSSNTWAKLPLPPNLISYIS 521
+CRFVI + + LPLP L+ Y++
Sbjct: 985 HMCRFVILKAVIRKDLIQTLPLPRRLLDYLN 1015
>UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p -
Drosophila melanogaster (Fruit fly)
Length = 342
Score = 74.9 bits (176), Expect = 2e-12
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 11/154 (7%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N WYWG I+ +++ L+ + FLVRDS S +SFR V TLH RL + + F+
Sbjct: 186 NQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFW 245
Query: 291 SLDNETFVPAYRLSE----HCSAVN----VKT-NLFE--MPVKLARPLNRFAKLDSLQKI 437
+ + + E C+ N VK N + PV L PL+R++ + LQ +
Sbjct: 246 HFEELKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQPPFPVILKYPLSRYSNMPKLQDL 305
Query: 438 CRFVIRQTGSSNTWAKLPLPPNLISYISMGSDYI 539
CR V+++ S A+LP+P ++ Y+S+ + +
Sbjct: 306 CRRVLQRQMSREQLAQLPVPAQMLEYLSVERELV 339
>UniRef50_UPI0000D9E331 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 7 (SOCS-7) (Nck, Ash and
phospholipase C gamma-binding protein) (Nck-associated
protein 4) (NAP-4), partial; n=1; Macaca mulatta|Rep:
PREDICTED: similar to Suppressor of cytokine signaling 7
(SOCS-7) (Nck, Ash and phospholipase C gamma-binding
protein) (Nck-associated protein 4) (NAP-4), partial -
Macaca mulatta
Length = 360
Score = 70.9 bits (166), Expect = 4e-11
Identities = 50/127 (39%), Positives = 63/127 (49%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG + +AE L G+ D FLVRDS D R+IL +SFR G T H R+ H
Sbjct: 203 GWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEH------- 255
Query: 297 DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIRQTGSSNT 476
YR L PV+L P++RF+ + SLQ +CRF IRQ +
Sbjct: 256 --------YR------------GLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDH 295
Query: 477 WAKLPLP 497
LPLP
Sbjct: 296 IPDLPLP 302
>UniRef50_UPI0000DB7AEC Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 5 (SOCS-5) (Cytokine-inducible
SH2-containing protein 5) (Cytokine-inducible SH2
protein 6) (CIS-6); n=1; Apis mellifera|Rep: PREDICTED:
similar to Suppressor of cytokine signaling 5 (SOCS-5)
(Cytokine-inducible SH2-containing protein 5)
(Cytokine-inducible SH2 protein 6) (CIS-6) - Apis
mellifera
Length = 475
Score = 69.3 bits (162), Expect = 1e-10
Identities = 53/139 (38%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
+YWG + EAE LL G+ + FL+RDS I VSFR GR+LHAR+ N FS D
Sbjct: 309 FYWGKMDRYEAERLLEGKQEGTFLLRDSAQEEFIFSVSFRKYGRSLHARIEQWNHKFSFD 368
Query: 300 NETFVPAYRLSEH-CSAV----NVKTNLFEMPVKLARPLNR-FAKLDSLQKICRFVIRQT 461
+ P SE C + + ++F P+ L P +R FA LQ +CR VI
Sbjct: 369 SHD--PGVYASETVCGLIEHYKHPSCSMFFEPM-LTIPFHRNFA--FPLQHLCRAVITTR 423
Query: 462 GSSNTWAKLPLPPNLISYI 518
+ + KL LP L SY+
Sbjct: 424 TTYDGINKLQLPKTLKSYL 442
>UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 509
Score = 66.5 bits (155), Expect = 8e-10
Identities = 55/166 (33%), Positives = 81/166 (48%), Gaps = 26/166 (15%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQ--HDNVFLVRDSYDSRHILCVSFRCVGRTL-HARLLHANGF 287
GWYWG ++ +AE +LA + + VFLVRDS D HIL ++ R V ++ H R+ H G
Sbjct: 332 GWYWGNMSWEDAESMLAQRPGEEGVFLVRDSQDPLHILTLTIRSVELSIHHVRVEHTEGK 391
Query: 288 FSL---DNETFVPAYRLSEHCSAVN-----------------VKT-NLFEMPV--KLARP 398
F L D A H + V +KT N+ E PV +L P
Sbjct: 392 FQLYDPDRGVSRGAANCVRHPNIVTFIKLAMKHSRSGTFIYFIKTRNMGEPPVQIRLLTP 451
Query: 399 LNRFAKLDSLQKICRFVIRQTGSSNTWAKLPLPPNLISYISMGSDY 536
++RF + SL+ RF IR + ++ LP+P +L Y+ + S Y
Sbjct: 452 ISRFTCVKSLKYYVRFTIRDSVPYDSITNLPIPHDLKEYL-LNSPY 496
>UniRef50_UPI00015B50BA Cluster: PREDICTED: similar to suppressors
of cytokine signalling; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to suppressors of cytokine signalling
- Nasonia vitripennis
Length = 527
Score = 63.7 bits (148), Expect = 6e-09
Identities = 49/138 (35%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
+YWG + EAE LL G+ + FL+RDS + VSFR R+LHAR+ N FS D
Sbjct: 361 FYWGKMDRYEAERLLEGKQEGTFLLRDSAQEEFLFSVSFRKYDRSLHARIEQWNHKFSFD 420
Query: 300 NETFVPAYRLSEHCSAV----NVKTNLFEMPVKLARPLNR-FAKLDSLQKICRFVIRQTG 464
+ Y C + + +F P+ L PL+R FA LQ +CR VI
Sbjct: 421 SHD-PGVYASKTVCGLIEHYKDPSCCMFFEPM-LTIPLHRNFA--FPLQHLCRAVITTHT 476
Query: 465 SSNTWAKLPLPPNLISYI 518
+ + KL LP L +Y+
Sbjct: 477 TYDGINKLQLPKTLKTYL 494
>UniRef50_Q29LD7 Cluster: GA13535-PA; n=1; Drosophila
pseudoobscura|Rep: GA13535-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 613
Score = 62.5 bits (145), Expect = 1e-08
Identities = 49/141 (34%), Positives = 69/141 (48%), Gaps = 5/141 (3%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N +YWG + EAE LL G+ + FL+RDS + V+FR GR+LHAR+ + F
Sbjct: 451 NSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKF 510
Query: 291 SLDNE-----TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIR 455
S D T L EH + +F P L PL+R + SLQ++ R I
Sbjct: 511 SFDCHDPCVFTAPTVTGLLEHYK--DPSCVMFFEPC-LTMPLHR-RQTFSLQQLARATIV 566
Query: 456 QTGSSNTWAKLPLPPNLISYI 518
+ S + +L LP L SY+
Sbjct: 567 SSTSYDGINQLELPGPLKSYL 587
>UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila
pseudoobscura|Rep: GA20849-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 891
Score = 62.5 bits (145), Expect = 1e-08
Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
++GWYWG ++ AE++L+ + D F+VRDS D +I +SF+ H R+ G F
Sbjct: 743 DYGWYWGPLSGEAAEKVLSNEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTF 802
Query: 291 SLDN-------------ETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQ 431
S + E V R + ++ + M V+L P++RF + SLQ
Sbjct: 803 SFGSYAKFKSQTITEFIEKAVEHSRSGRYLFFLHRRPEHGPMRVQLTNPVSRFKHVQSLQ 862
Query: 432 KICR 443
+CR
Sbjct: 863 HMCR 866
>UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 155
Score = 61.3 bits (142), Expect = 3e-08
Identities = 47/141 (33%), Positives = 69/141 (48%), Gaps = 5/141 (3%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL---LHAN 281
N WYWG I EAE +L G D FL+RDS +++ VSFR RT HAR+ H
Sbjct: 13 NCPWYWGKINRFEAERVLDGLPDGTFLLRDSAQYQYLFSVSFRRYFRTYHARIEQWKHRY 72
Query: 282 GFFSLDNETFV--PAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIR 455
F + +F + L +H S + ++ P+ L L R L LQ +CR I
Sbjct: 73 SFDKPSDYSFCSKTLHELLQHYS--QAEQCMYYEPL-LLNALPRKNTL-PLQHLCRATIC 128
Query: 456 QTGSSNTWAKLPLPPNLISYI 518
+ S +LP+P +L +++
Sbjct: 129 KNVSFQDVDELPIPKSLQTFL 149
>UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|Rep:
CG15154-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 720
Score = 60.5 bits (140), Expect = 6e-08
Identities = 48/141 (34%), Positives = 68/141 (48%), Gaps = 5/141 (3%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N +YWG + EAE LL G+ + FL+RDS + V+FR GR+LHAR+ + F
Sbjct: 471 NSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKF 530
Query: 291 SLDNE-----TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIR 455
S D T L EH + +F P L PL+R + SLQ++ R I
Sbjct: 531 SFDCHDPCVFTAPTVTGLLEHYK--DPACVMFFEPC-LTIPLHR-RQTFSLQQLSRATIV 586
Query: 456 QTGSSNTWAKLPLPPNLISYI 518
S + ++ LP L SY+
Sbjct: 587 SNTSYDGINQMELPGRLKSYL 607
>UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=31;
Euteleostomi|Rep: Suppressor of cytokine signaling 5 -
Homo sapiens (Human)
Length = 536
Score = 59.7 bits (138), Expect = 1e-07
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 5/137 (3%)
Frame = +3
Query: 123 YWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD- 299
YWG + EAE LL G+ + FL+RDS ++ VSFR R+LHAR+ N FS D
Sbjct: 382 YWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDA 441
Query: 300 NETFV----PAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIRQTGS 467
++ V L EH + + +F P+ L LNR SLQ ICR VI + +
Sbjct: 442 HDPCVFHSSTVTGLLEHYK--DPSSCMFFEPL-LTISLNRTFPF-SLQYICRAVICRCTT 497
Query: 468 SNTWAKLPLPPNLISYI 518
+ LPLP L ++
Sbjct: 498 YDGIDGLPLPSMLQDFL 514
>UniRef50_Q91ZA6 Cluster: Suppressor of cytokine signaling 4; n=10;
Amniota|Rep: Suppressor of cytokine signaling 4 - Mus
musculus (Mouse)
Length = 436
Score = 58.4 bits (135), Expect = 2e-07
Identities = 49/141 (34%), Positives = 69/141 (48%), Gaps = 5/141 (3%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFF 290
N+ YWG + AE LL G+ + FL+RDS ++ VSFR R+LHAR+ N F
Sbjct: 280 NNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNF 339
Query: 291 SLD-NETFV----PAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIR 455
S D ++ V L EH + +F P+ L+ PL R SLQ ICR VI
Sbjct: 340 SFDAHDPCVFHSPDITGLLEHYK--DPSACMFFEPL-LSTPLIRTFPF-SLQHICRTVIC 395
Query: 456 QTGSSNTWAKLPLPPNLISYI 518
+ + LP+P + Y+
Sbjct: 396 NCTTYDGIDALPIPSPMKLYL 416
>UniRef50_O45498 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 192
Score = 58.0 bits (134), Expect = 3e-07
Identities = 50/164 (30%), Positives = 68/164 (41%), Gaps = 18/164 (10%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANG----- 284
WYWG + AE LL FL+RDS H+ VS+ R H+RL +
Sbjct: 16 WYWGDLDWKWAERLLLLCPIGYFLIRDSRSETHLFTVSYHFQDRVYHSRLSLEDSRRNLG 75
Query: 285 ----FFSLDNETFVPAYRLSEHCSAVNVKTNLF--------EMPVKLARPLNRFAKLDSL 428
+ S D V S S + L V L RPL + L SL
Sbjct: 76 SRQPYVSRDYWNLVEIIERSLEQSLTGQQEMLHYRRGHEAEAARVNLTRPLTKRELLPSL 135
Query: 429 QKICRFVIRQTGSSNTWAK-LPLPPNLISYISMGSDYIIP*LSR 557
Q +CRF ++ + K PLPP ++ Y+S S +IIP L +
Sbjct: 136 QYLCRFTLKTSQQKPPTPKTAPLPPTILKYLS-DSKWIIPDLKK 178
>UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=26;
Euteleostomi|Rep: Suppressor of cytokine signaling 2 -
Homo sapiens (Human)
Length = 198
Score = 57.2 bits (132), Expect = 5e-07
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 17/151 (11%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG +T +EA+E L + FL+RDS S ++L +S + + R+ + +G F L
Sbjct: 47 GWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRL 106
Query: 297 DNETFVPAYRLSEHCSAVNV----------KTNLFEMP------VKLARPLNRFAKLDSL 428
D+ V + +L + S V++ K E P + L +PL + SL
Sbjct: 107 DSIICVKS-KLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPL--YTSAPSL 163
Query: 429 QKICRFVIRQ-TGSSNTWAKLPLPPNLISYI 518
Q +CR I + TG+ W LPLP L Y+
Sbjct: 164 QHLCRLTINKCTGA--IWG-LPLPTRLKDYL 191
>UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep:
Zgc:154062 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 212
Score = 56.8 bits (131), Expect = 7e-07
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 24/158 (15%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWGGI++SEA +L G + FL+RDS ++L +S + V + R+ + FSL
Sbjct: 50 GWYWGGISASEAHSVLKGASEGTFLIRDSSHPDYMLTLSVKTVRGPTNVRIEYRQCRFSL 109
Query: 297 DN--------ETFVPAYRLSEHCSAVNVKTNLFEMP----------------VKLARPLN 404
D+ ++F + L +H + N +M +KL +P++
Sbjct: 110 DSSSPARSHLQSFPDVHSLVQHYVGSKSEKNEEKMEEAHHVISSAPKECSVLLKLKKPIH 169
Query: 405 RFAKLDSLQKICRFVIRQTGSSNTWAKLPLPPNLISYI 518
SL+ + R VI + SS LPLP L+ Y+
Sbjct: 170 CPQGFPSLKHLTRLVINKHTSST--EMLPLPNPLLYYL 205
>UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 213
Score = 54.4 bits (125), Expect = 4e-06
Identities = 46/162 (28%), Positives = 73/162 (45%), Gaps = 20/162 (12%)
Frame = +3
Query: 93 FQEAN*NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLL 272
FQ N GWYWGG+T+ +A L G + FLVRDS ++ +S + + R+
Sbjct: 48 FQHLN-TSGWYWGGLTAGDARAALIGAPEGTFLVRDSSHPLYLFTLSVQTWRGPTNIRIE 106
Query: 273 HANGFFSLDNE--------TFVPAYRLSEHCSAV------------NVKTNLFEMPVKLA 392
+ +G F LD+ +F L H S+ ++ + +KL
Sbjct: 107 YDSGRFRLDSSFPARSCLLSFSALPSLVHHYSSARPEEEKKAEDHHHMVAKDTGILLKLR 166
Query: 393 RPLNRFAKLDSLQKICRFVIRQTGSSNTWAKLPLPPNLISYI 518
+PL+R +LQ + R I + +T KLPLP L+ Y+
Sbjct: 167 KPLHRPQAFPTLQHLTRLTINRHTDCHT--KLPLPRPLLLYL 206
>UniRef50_Q4H2S6 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 696
Score = 53.6 bits (123), Expect = 6e-06
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWGG++ EA+ L G FL+RDS D R++ +S R+++ NG F D
Sbjct: 502 WYWGGMSGQEAKRKLRGSSPGTFLLRDSADPRYLYSLSLMTKSGPTSIRIVYNNGRFRFD 561
Query: 300 NE 305
+E
Sbjct: 562 SE 563
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/73 (35%), Positives = 38/73 (52%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WY+G I+ AE+LL + FLVRDS + L +S R + R H ++ + +G +
Sbjct: 301 WYFGRISRERAEDLLLHGREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVDGLLKIG 360
Query: 300 NETFVPAYRLSEH 338
N TFV L H
Sbjct: 361 NRTFVDMNALINH 373
>UniRef50_A7RUJ8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 186
Score = 52.0 bits (119), Expect = 2e-05
Identities = 46/152 (30%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YW GIT +A+ +L F++RDS + +S R V + R+ G FSL
Sbjct: 29 GFYWRGITKEQADIILRSCDMGAFIIRDSSSPNFLFTLSVRTVFGVTNIRIAMDRGRFSL 88
Query: 297 ---DNETFV-PAYRLSEHCSAVNVKTN-----------LFEMPVKLARPLNR--FAKLDS 425
DNE P+++ H VK + L P K L R + + S
Sbjct: 89 ESIDNENSEGPSFKCVVHLIYYYVKNSRHSERHLEDNYLRREPTKYKLYLGRPIYGAVSS 148
Query: 426 LQKICRFVIRQTGSSNTWAKLPLPPNLISYIS 521
LQ +CR I + N LP+P L YIS
Sbjct: 149 LQHLCRRSINKQMRPNGVYALPIPAKLKIYIS 180
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHANGFFS 293
W+ G IT ++AE+LL +FLVR+S + + LCVS C G+ H R+++ NG +
Sbjct: 18 WFHGKITRNQAEQLLCPPETGLFLVRESTNFPGDYTLCVS--CDGKVEHYRIIYHNGKLT 75
Query: 294 LDNET-FVPAYRLSEH 338
+D E F +L EH
Sbjct: 76 IDEEEYFENLMQLVEH 91
>UniRef50_Q4RXL6 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 243
Score = 50.8 bits (116), Expect = 4e-05
Identities = 26/63 (41%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFR-CVGRTLHARLLHANGFFS 293
GWYWG + SEA+E L + + FL+RDS +H+L +S + C G T R+ ++ G F
Sbjct: 64 GWYWGPTSVSEAQEALMKKPEGTFLMRDSSHPKHMLTLSVQTCCGPT-SVRVDYSRGSFW 122
Query: 294 LDN 302
LD+
Sbjct: 123 LDS 125
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 50.8 bits (116), Expect = 4e-05
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLH-ANGF 287
NH WY+G IT ++AE+LL+ +H+ FL+R S S +S +C H ++L A G
Sbjct: 31 NHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGK 90
Query: 288 FSL 296
F L
Sbjct: 91 FFL 93
>UniRef50_O14543 Cluster: Suppressor of cytokine signaling 3; n=21;
Mammalia|Rep: Suppressor of cytokine signaling 3 - Homo
sapiens (Human)
Length = 225
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YW +T EA LL+ + FL+RDS D RH +S + T + R+ G FSL
Sbjct: 45 GFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSL 104
Query: 297 DNE 305
++
Sbjct: 105 QSD 107
>UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing protein;
n=26; Tetrapoda|Rep: Cytokine-inducible SH2-containing
protein - Homo sapiens (Human)
Length = 258
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/62 (37%), Positives = 35/62 (56%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWYWG IT+SEA + L + FLVRDS ++ +S + + R+ +A+ F L
Sbjct: 81 GWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRL 140
Query: 297 DN 302
D+
Sbjct: 141 DS 142
>UniRef50_UPI000069EEDB Cluster: UPI000069EEDB related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069EEDB UniRef100 entry -
Xenopus tropicalis
Length = 163
Score = 50.4 bits (115), Expect = 6e-05
Identities = 39/114 (34%), Positives = 54/114 (47%), Gaps = 5/114 (4%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YWG + + EA +L + FLVRDS H+ VS + + R+L GFF
Sbjct: 32 GFYWGPLPTKEAHAMLEREQIGTFLVRDSSQGNHLFSVSIKMESGPVSVRVLFLKGFF-- 89
Query: 297 DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLA-----RPLNRFAKLDSLQKICR 443
L E CS VK L E+ V+ RPL R ++ SLQ++CR
Sbjct: 90 ---------WLRELCSDCPVK--LLELAVEKCQQTPLRPLRR-TRILSLQQMCR 131
>UniRef50_Q90X67 Cluster: Suppressor of cytokine signaling 3; n=13;
Euteleostomi|Rep: Suppressor of cytokine signaling 3 -
Gallus gallus (Chicken)
Length = 209
Score = 50.4 bits (115), Expect = 6e-05
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YW +T EA LL+ + FL+RDS D RH +S + T + R+ G FSL
Sbjct: 45 GFYWSTVTGGEANVLLSAEPAGTFLIRDSSDQRHFFTLSVKTESGTKNLRIQCEGGSFSL 104
Query: 297 DNE 305
++
Sbjct: 105 QSD 107
>UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=15;
Tetrapoda|Rep: Suppressor of cytokine signaling 1 - Homo
sapiens (Human)
Length = 211
Score = 49.2 bits (112), Expect = 1e-04
Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 2/137 (1%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YWG ++ A E L + FLVRDS +S + R+ G F L
Sbjct: 78 GFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHL 137
Query: 297 D--NETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIRQTGSS 470
D E+F + L EH A + L PL R ++ LQ++CR I T
Sbjct: 138 DGSRESFDCLFELLEHYVAAPRR--------MLGAPL-RQRRVRPLQELCRQRIVATVGR 188
Query: 471 NTWAKLPLPPNLISYIS 521
A++PL P L Y+S
Sbjct: 189 ENLARIPLNPVLRDYLS 205
>UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 227
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWY G +T EA+ L + FLVRDS D R++ +S + T R+ + +G F L
Sbjct: 54 GWYHGAMTYREAKLKLKSCSNGTFLVRDSSDDRYLYTLSVKTPRGTTSVRIEYEDGLFML 113
Query: 297 DNE 305
D+E
Sbjct: 114 DSE 116
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 48.8 bits (111), Expect = 2e-04
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQ-HDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WY+G IT S+ + +L G HD FL+RDS + VS + GR H R+ + +
Sbjct: 448 WYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCI 507
Query: 297 DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPL 401
F +L +H + TN + L R L
Sbjct: 508 GQRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSL 542
>UniRef50_UPI0000D56C32 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2
protein 2) (CIS-2); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Suppressor of cytokine signaling 2
(SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) -
Tribolium castaneum
Length = 252
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/68 (35%), Positives = 35/68 (51%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWY+ G+T ++ELL FLVR+S D R + +S + RL + NG F L
Sbjct: 94 GWYYEGLTFDRSDELLKDTRVGTFLVRNSSDPRFLFSLSVQTDRGPKSVRLFYTNGHFRL 153
Query: 297 DNETFVPA 320
D + + A
Sbjct: 154 DAQPHLQA 161
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 47.6 bits (108), Expect = 4e-04
Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGR-TLHARLLHANGFF 290
W+ G I+ EA + L D +FLVR+S + ++LCVSF GR +H R+LH +G
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSF---GRDVIHYRVLHRDGHL 178
Query: 291 SLDNETF 311
++D F
Sbjct: 179 TIDEAVF 185
>UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91868
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 201
Score = 47.2 bits (107), Expect = 6e-04
Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 3/137 (2%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YWG +T EA L + FL+RDS S +S++ + R+ N FSL
Sbjct: 68 GFYWGPMTVEEAHLKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRINFKNSKFSL 127
Query: 297 --DNETFVPAYRLSEHCSAVNVKTNLFEMPVK-LARPLNRFAKLDSLQKICRFVIRQTGS 467
E+F ++L EH P K L RP R + SLQ++CR I +
Sbjct: 128 TGSKESFDSLFKLLEH---------YISSPKKGLIRPC-RKEPVQSLQQLCRRQIMERCD 177
Query: 468 SNTWAKLPLPPNLISYI 518
+P+ P L ++
Sbjct: 178 GKDIDCIPVQPILKDFL 194
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 46.8 bits (106), Expect = 7e-04
Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHANGFFS 293
W+ G IT +AE LL +FLVR+S Y + LCVS C G+ H R+++ S
Sbjct: 82 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVS--CDGKVEHYRIMYHASKLS 139
Query: 294 LDNET-FVPAYRLSEH 338
+D E F +L EH
Sbjct: 140 IDEEVYFENLMQLVEH 155
>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
to Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K) - Apis mellifera
Length = 1256
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG IT E E + D FLVRD+ ++ R G ++ NG +
Sbjct: 839 WYWGDITRDEVNEKMIDSPDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRNGKYGFS 898
Query: 300 NE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSL 428
F L +H ++ + +KL P++RF + D +
Sbjct: 899 EPYNFHSVIELVDHYRNCSLAQYNSTLDIKLLYPVSRFQQDDEI 942
>UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2;
Xenopus tropicalis|Rep: Suppressor of cytokine signaling
3 - Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 211
Score = 46.0 bits (104), Expect = 0.001
Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YW ++ +EA++LL+ Q FL+RDS D H+ +S R + R+ F L
Sbjct: 54 GYYWSTLSGTEAKKLLSDQPVGSFLIRDSSDHHHLFTLSLRTSAGITNLRIKLEGPSFYL 113
Query: 297 DN-------ETFVPAYRLSEHCSAVN-----------VKTNLFEMPVKLARPLNRFAKLD 422
+ TF +L EH + ++ N +P+ L +PLN K+
Sbjct: 114 ETVAGAESPHTFPCVVKLVEHYMRLTAAGESDSNLCYIEGNDQPVPLMLTQPLN--CKVV 171
Query: 423 SLQKICR 443
SLQ +C+
Sbjct: 172 SLQYLCK 178
>UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 220
Score = 44.8 bits (101), Expect = 0.003
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG +T+++A L + FLVRDS ++L +S R R+ +++ F LD
Sbjct: 57 WYWGAVTAAQAHAALQEASEGAFLVRDSSHPLYMLTLSVRTARGPTSIRIQYSSARFLLD 116
Query: 300 NET 308
+ +
Sbjct: 117 SSS 119
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 44.4 bits (100), Expect = 0.004
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHANGFFS 293
W+ G IT EAE LL + D +FLVR+S + + LCV F+ + H R+ + +
Sbjct: 479 WFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQ--SKVEHYRVKYLENKLT 536
Query: 294 LDNETF 311
+D+E +
Sbjct: 537 IDDEEY 542
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 43.6 bits (98), Expect = 0.007
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
H WY G ++ S AE LL+ + FLVR+S S L +S R GR H R+
Sbjct: 171 HSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRI 222
>UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b); n=17;
Eutheria|Rep: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b) - Homo
sapiens (Human)
Length = 402
Score = 42.7 bits (96), Expect = 0.012
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 2/107 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WYWG I+ E + L D FLVRD S + ++ R G ++ H +G +
Sbjct: 65 WYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGF 124
Query: 297 -DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQK 434
D TF L H ++ ++ VKL P++R+ + D L K
Sbjct: 125 SDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQ-DQLVK 170
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 42.3 bits (95), Expect = 0.016
Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Frame = +3
Query: 84 KIKFQEAN*NHGWYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVS 233
K F ++N H W++GGIT SE + LL + FLVRDS +LCVS
Sbjct: 7 KAPFDDSN-KHLWHFGGITRSETDNLLIQKRPGTFLVRDSRTCPGDSVLCVS 57
>UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae
str. PEST
Length = 397
Score = 41.9 bits (94), Expect = 0.021
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 1/98 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG I+ A+E + D FLVRD+ + + + G ++ H NG +
Sbjct: 142 WYWGKISRDVAKEKMMDAPDGSFLVRDAINDAGEFTLVLKKDGTDRPIKIYHKNGKYGFT 201
Query: 300 NE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRF 410
E TF + +K + + L P++RF
Sbjct: 202 QECTFESLVGMINEFRTTTLKEYNTILDISLLYPISRF 239
>UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311;
n=1; Danio rerio|Rep: hypothetical protein LOC406311 -
Danio rerio
Length = 394
Score = 41.5 bits (93), Expect = 0.027
Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WYW I+ E E+L G D FLVRD S + ++ R G R+LH G F
Sbjct: 6 WYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVRNNGTNKLIRILHQEGKFGF 65
Query: 297 DNE-TF--VP-AYRLSEHCSAVNVKTNLFEMPVKLARPL 401
TF VP H S V+ T+L V LA P+
Sbjct: 66 SEPLTFSSVPELISFYRHRSLVHYNTSL---DVTLAYPV 101
>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 723
Score = 41.5 bits (93), Expect = 0.027
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WYWG I+ E E L D FLVRD S ++ R G ++ H G +
Sbjct: 362 WYWGEISREEVNEKLRDTPDGTFLVRDASSKLEGEYTLTLRKGGNNKLIKIYHREGRYGF 421
Query: 297 DNE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKL 419
TF+ L H ++ ++ KL P++++ +L
Sbjct: 422 SEPLTFLSVVELINHYRHESLAQYNAKLDTKLLYPVSKYQQL 463
Score = 37.9 bits (84), Expect = 0.34
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLH 260
WY G I S+AEE+L G D FL+R+S + S G T H
Sbjct: 622 WYVGDIKRSQAEEMLRGTCDGTFLIRESQTQKGSYACSVVVDGDTKH 668
>UniRef50_Q60UZ3 Cluster: Putative uncharacterized protein CBG19761;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG19761 - Caenorhabditis
briggsae
Length = 239
Score = 41.5 bits (93), Expect = 0.027
Identities = 19/50 (38%), Positives = 25/50 (50%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
WYWG + AE LL FL+RDS H+ VS+ + H+RL
Sbjct: 8 WYWGDLDWKWAERLLLLCPVGYFLIRDSRSETHLFTVSYHAEDKVYHSRL 57
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 41.5 bits (93), Expect = 0.027
Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHANGFFS 293
W+ G I EAE LL + D +FLVR+S + + LCV F + H R+ +A +
Sbjct: 378 WFHGRIKREEAENLLKPREDGLFLVRESTNFPGDYTLCVCFN--EKVEHYRIKYAENKLT 435
Query: 294 L-DNETFVPAYRLSEH 338
+ D+E F +L EH
Sbjct: 436 IDDDEYFDNLGQLVEH 451
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 41.5 bits (93), Expect = 0.027
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Frame = +3
Query: 120 WYWGGITSSEAEELLA-GQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANG---F 287
WY G ++ A+ELL G D FLVR+S + +S C G H ++ G F
Sbjct: 10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRRHGGEDAF 69
Query: 288 FSLDNE 305
FS+D++
Sbjct: 70 FSIDDK 75
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 41.1 bits (92), Expect = 0.036
Identities = 17/28 (60%), Positives = 19/28 (67%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS 203
WYWG ++ EA LL GQ VFLVRDS
Sbjct: 13 WYWGRLSRQEAVSLLQGQRHGVFLVRDS 40
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 41.1 bits (92), Expect = 0.036
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQ-HDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WY+G +T +AE L + H+ FL+RDS S + VS + G+ H ++ + +
Sbjct: 28 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 87
Query: 297 DNETFVPAYRLSEHCSAVNVKTN 365
F L EH + T+
Sbjct: 88 GQRKFSTMEELVEHYKKAPIFTS 110
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 41.1 bits (92), Expect = 0.036
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHANGFFS 293
W+ G I+ AE LL + D +FLVR+S + + LCV F+ + H R+ NG +
Sbjct: 101 WFHGKISRELAESLLMPREDGLFLVRESAHFPGDYTLCVCFQ--DQVDHYRMQGKNGKLT 158
Query: 294 LDNETF 311
+D E +
Sbjct: 159 IDEEVY 164
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 41.1 bits (92), Expect = 0.036
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHA-NGFF 290
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+ A +G
Sbjct: 377 HSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKL 436
Query: 291 SLDNET-FVPAYRLSEHCSAV 350
+ +E+ F L H S V
Sbjct: 437 YVSSESRFNTLAELVHHHSTV 457
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 40.3 bits (90), Expect = 0.063
Identities = 21/52 (40%), Positives = 28/52 (53%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
H WY G I+ + AE LL+ + FLVR+S S +S R GR H R+
Sbjct: 173 HSWYHGRISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 224
>UniRef50_UPI0000DB734C Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2
protein 2) (CIS-2) (STAT-induced STAT inhibitor 2)
(SSI-2); n=1; Apis mellifera|Rep: PREDICTED: similar to
Suppressor of cytokine signaling 2 (SOCS-2)
(Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced
STAT inhibitor 2) (SSI-2) - Apis mellifera
Length = 602
Score = 40.3 bits (90), Expect = 0.063
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
GWY G++ ++E LL +L+RDS DSR++ VS + R+ + G F L
Sbjct: 448 GWYHEGLSWQQSENLLKNAMIGRWLMRDSSDSRYMFAVSVQTARGPTSVRVHYFVGQFRL 507
Query: 297 DNE 305
D E
Sbjct: 508 DAE 510
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 40.3 bits (90), Expect = 0.063
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHA-NGFF 290
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+ A +G
Sbjct: 464 HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKL 523
Query: 291 SLDNET-FVPAYRLSEHCSAV 350
+ +E+ F L H S V
Sbjct: 524 YVSSESRFNTLAELVHHHSTV 544
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 40.3 bits (90), Expect = 0.063
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHA-NGFF 290
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+ A +G
Sbjct: 114 HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKL 173
Query: 291 SLDNET-FVPAYRLSEHCSAV 350
+ +E+ F L H S V
Sbjct: 174 YVSSESRFNTLAELVHHHSTV 194
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 40.3 bits (90), Expect = 0.063
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHA-NGFF 290
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+ A +G
Sbjct: 11 HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKL 70
Query: 291 SLDNET-FVPAYRLSEHCSAV 350
+ +E+ F L H S V
Sbjct: 71 YVSSESRFNTLAELVHHHSTV 91
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 40.3 bits (90), Expect = 0.063
Identities = 21/52 (40%), Positives = 28/52 (53%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
H WY G I+ + AE LL+ + FLVR+S S +S R GR H R+
Sbjct: 252 HSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 303
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 40.3 bits (90), Expect = 0.063
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHA-NGFF 290
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+ A +G
Sbjct: 125 HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKL 184
Query: 291 SLDNET-FVPAYRLSEHCSAV 350
+ +E+ F L H S V
Sbjct: 185 YVSSESRFNTLAELVHHHSTV 205
>UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73230
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 321
Score = 39.9 bits (89), Expect = 0.084
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFF 290
WYW I+ E E+L G D FLVRD S + ++ R G R+LH G F
Sbjct: 32 WYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVRNNGTNKLIRILHQEGKF 89
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 39.9 bits (89), Expect = 0.084
Identities = 20/52 (38%), Positives = 28/52 (53%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
H WY G ++ + AE LL+ + FLVR+S S +S R GR H R+
Sbjct: 74 HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 125
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 39.5 bits (88), Expect = 0.11
Identities = 21/52 (40%), Positives = 27/52 (51%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
H WY G I + AE LL+ + FLVR+S S +S R GR H R+
Sbjct: 172 HSWYHGRICRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 223
>UniRef50_UPI0000F1D282 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 186
Score = 39.1 bits (87), Expect = 0.15
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 2/136 (1%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G+YWG + EA LA FL+RDS + +S+R R+L N FSL
Sbjct: 53 GFYWGPLDVDEAHARLANLPLGTFLIRDSMQANVFFTLSYRAPEGPTSVRVLLKNESFSL 112
Query: 297 --DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKICRFVIRQTGSS 470
TF + L + A K+ L+RP R +LQ++ R + Q+
Sbjct: 113 AGSKHTFSCIFGLLGYYIASPKKS--------LSRPY-RGDVPQTLQELARRAVVQSFGK 163
Query: 471 NTWAKLPLPPNLISYI 518
++ LP+ L +I
Sbjct: 164 DSIPHLPVSKKLKEFI 179
>UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit beta; n=114; Euteleostomi|Rep:
Phosphatidylinositol 3-kinase regulatory subunit beta -
Homo sapiens (Human)
Length = 728
Score = 39.1 bits (87), Expect = 0.15
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WYWG I+ E E L D FLVRD S + ++ R G ++ H +G +
Sbjct: 330 WYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGF 389
Query: 297 DNE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRF 410
TF L H ++ ++ +L P++++
Sbjct: 390 SEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKY 428
Score = 39.1 bits (87), Expect = 0.15
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLH-ANGF-FS 293
WY G I ++AEE+L+G+ D FL+R+S R S G T H + A GF F+
Sbjct: 622 WYVGKINRTQAEEMLSGKRDGTFLIRES-SQRGCYACSVVVDGDTKHCVIYRTATGFGFA 680
Query: 294 LDNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPL 401
+ L H ++ + + V LA P+
Sbjct: 681 EPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPV 716
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 38.7 bits (86), Expect = 0.19
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS 203
WYWG I+ EA+ +L G+ D FLVRD+
Sbjct: 32 WYWGRISREEAKSILHGKPDGSFLVRDA 59
>UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor
receptor bound protein 14; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to growth factor receptor bound
protein 14 - Tribolium castaneum
Length = 655
Score = 38.3 bits (85), Expect = 0.26
Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +3
Query: 120 WYWGGITSSEAEELLA--GQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
W+ G++ +A L+ G D VFLVR+S + ++++C G+ LHA++
Sbjct: 533 WFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVLHAQI 584
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 38.3 bits (85), Expect = 0.26
Identities = 15/28 (53%), Positives = 18/28 (64%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS 203
WYWG ++ +A LL GQ FLVRDS
Sbjct: 248 WYWGRLSRGDAVSLLQGQRHGTFLVRDS 275
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 37.9 bits (84), Expect = 0.34
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQH-DNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WY+G +T +AE L + + FL+RDS S H +S + + H ++ + +
Sbjct: 297 WYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESLYCI 356
Query: 297 DNETFVPAYRLSEHCSAVNVKTN 365
F L EH + T+
Sbjct: 357 GQRKFHSMEELVEHYKKAPIFTS 379
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 37.9 bits (84), Expect = 0.34
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLH-ANG- 284
++ WY G ++ E LL FLVR S + L V+ R +GR H R+ + G
Sbjct: 75 SYSWYHGAVSRQAGEHLLRSGITGSFLVRASESAPGQLSVTVRHLGRVYHYRISQDSRGL 134
Query: 285 FFSLDNETFVPAYRLSEHCS 344
F+ + F +L EH S
Sbjct: 135 FYITEAHRFPTVVQLIEHHS 154
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 37.9 bits (84), Expect = 0.34
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQH-DNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WY+G +T +AE L + + FL+RDS S VS + G+ H ++ + + +
Sbjct: 285 WYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCI 344
Query: 297 DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPL 401
F L EH + T+ + L R L
Sbjct: 345 GQRRFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 379
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 37.5 bits (83), Expect = 0.45
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILC-VSFRCVGRTLHARLLH-ANGF 287
W++G IT +AEELL + +FLVR+S + + LC VS + + H R++ ++
Sbjct: 92 WFFGKITREKAEELLTPREVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRVISTSDNQ 151
Query: 288 FSLDNETFVP 317
++D E F P
Sbjct: 152 VTVDEEAFFP 161
>UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to
phosphoinositide-3-kinase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to
phosphoinositide-3-kinase - Strongylocentrotus
purpuratus
Length = 820
Score = 37.1 bits (82), Expect = 0.59
Identities = 15/28 (53%), Positives = 16/28 (57%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS 203
WYWG I+ E E L D FLVRDS
Sbjct: 502 WYWGSISREEVNEKLKDMPDGTFLVRDS 529
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 37.1 bits (82), Expect = 0.59
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARL-LHANGFF 290
W+ G I+ +AE+LL + FLVR+S Y + LCVS+ GR + R+ + G
Sbjct: 109 WFHGRISREDAEKLLTPPKNGRFLVRESQNYPGDYTLCVSYD--GRVENYRVRRNEKGLV 166
Query: 291 SL-DNETFVPAYRLSEH 338
++ D+E F +L EH
Sbjct: 167 TVDDDEYFDNLIKLVEH 183
>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
3-kinase regulatory subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 568
Score = 37.1 bits (82), Expect = 0.59
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG I E +E + D FLVRD+ ++ + G ++ H +
Sbjct: 186 WYWGNINRDEVKEKMTDVPDGSFLVRDASSGNGEYTLTLKKDGADRVIKIFHTQDKYGFT 245
Query: 300 NE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRF 410
+ + L V++K + +KL P++RF
Sbjct: 246 RDGSHNSVVDLINFYRNVSLKEYNTILDIKLMYPISRF 283
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 36.7 bits (81), Expect = 0.78
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQ-HDNVFLVRDSYDSRHILCVSFRCVGRTLHARLL 272
H W++G I ++AEE+L+ Q HD FL+R+S + +S + H ++L
Sbjct: 58 HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVL 111
>UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit
protein 1; n=2; Caenorhabditis|Rep: Phosphoinositide
kinase adapter subunit protein 1 - Caenorhabditis
elegans
Length = 522
Score = 36.7 bits (81), Expect = 0.78
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRD-SYDSRHILCVSFRCVGRTLHARLLHANGFFS 293
GWYW S + L+ Q D F+VR+ S + L V F + L + F+
Sbjct: 19 GWYWADADRSAVSKALSDQPDGSFIVRNASTPGDYTLSVKFAAQVKLLRIVVKDGKCGFN 78
Query: 294 LDNETFVPAYRLSEHCSAVNVKTNLFE--MPVKLARPLN 404
D+ T RL E N+ N+F + V+L P++
Sbjct: 79 TDSLTHDSVVRLIEFHR--NISLNIFNDALDVRLLYPVS 115
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 36.7 bits (81), Expect = 0.78
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Frame = +3
Query: 111 NHG-WYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCVSFRCVGRTLHARLLHAN 281
NH W+ I+ E+LL G+ D FLVR+S + LC+SF G+ H R+ +
Sbjct: 147 NHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFH--GKVEHYRIEQTS 204
Query: 282 G 284
G
Sbjct: 205 G 205
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 36.7 bits (81), Expect = 0.78
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQ-HDNVFLVRDSYDSRHILCVSFRCVGRTLHARLL 272
H W++G I ++AEE+L+ Q HD FL+R+S + +S + H ++L
Sbjct: 58 HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVL 111
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 36.3 bits (80), Expect = 1.0
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLL--HANGFF 290
GWY G I+ +AE++L + FLVR+S +R ++ + +H R+ H G F
Sbjct: 942 GWYHGSISRIDAEKILRPLGEGSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDHETGQF 1001
Query: 291 SL 296
L
Sbjct: 1002 IL 1003
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 35.9 bits (79), Expect = 1.4
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
GW+ G IT EAE +L + FLVR+S ++ +S + +H R+
Sbjct: 769 GWFHGAITRVEAENVLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRI 819
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 35.9 bits (79), Expect = 1.4
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +3
Query: 90 KFQEAN*NHGWYWGGITSSEAEELLAGQHDNVFLVRDS 203
+F A+ WY+G ++ EA+ L GQ +FLVRDS
Sbjct: 5 RFDSAD-RSAWYFGPVSRHEAQNRLQGQKHGIFLVRDS 41
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 35.9 bits (79), Expect = 1.4
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAG-QHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
WY ++ +AE +L D FLVR +S H +SFR G+ H R+ F L
Sbjct: 619 WYHSSLSRVQAEHMLMRVPRDGAFLVRKRSES-HSYAISFRAEGKIKHCRIQQEGRLFML 677
Score = 35.1 bits (77), Expect = 2.4
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Frame = +3
Query: 114 HGWYWGGITSSE-AEELL-----AGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLH 275
HG GG + AE+LL G D FLVR+S +SF GR H R+
Sbjct: 504 HGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHS 563
Query: 276 -----ANGFFSLDNETFVPAYRLSEHCSAVNVKTNLFEM 377
+ F+ DN F YRL H ++ N FEM
Sbjct: 564 RQESGSTRFYLTDNLVFDSLYRLMCHYRDTPLRCNEFEM 602
>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 271
Score = 35.9 bits (79), Expect = 1.4
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLA--GQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGF 287
HGW + G++ +AEELL+ G FL+R+S R + +S R H + H
Sbjct: 82 HGWLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVR------HRSVKHYK-I 134
Query: 288 FSLDNETFVPAYRLSEHC 341
F L N + + RL+ C
Sbjct: 135 FRLTNSWYYISPRLTFQC 152
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
GWY G IT EAE +L + +LVR+S ++ +S + +H R+
Sbjct: 1080 GWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRI 1130
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/49 (38%), Positives = 26/49 (53%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHAR 266
WY G +T SEAE LL + +LVR S SR+ +S R +H +
Sbjct: 221 WYHGALTRSEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMK 269
>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
protein, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
protein, partial - Strongylocentrotus purpuratus
Length = 926
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLH 260
+H W+ GGI+ +AE+L+ D FLVRDS ++ R G ++H
Sbjct: 123 SHAWFHGGISREKAEKLIRENGD--FLVRDSISKPGNFVLTVRWKGVSMH 170
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
GWY G IT EAE +L + +LVR+S ++ +S + +H R+
Sbjct: 1020 GWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRI 1070
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 35.5 bits (78), Expect = 1.8
Identities = 16/51 (31%), Positives = 28/51 (54%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
GWY G I+ +AE++L + FLVR+S +R ++ + +H R+
Sbjct: 608 GWYHGSISRIDAEKILRPLSEGSFLVRNSESTRQDYSLTLKSAKGFMHMRI 658
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/50 (38%), Positives = 26/50 (52%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
WY G I+ S++E +L FLVR+S S +S R GR H R+
Sbjct: 194 WYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRI 243
>UniRef50_UPI0000447279 Cluster: PREDICTED: similar to suppressor of
cytokine signalling 1; n=2; Gallus gallus|Rep:
PREDICTED: similar to suppressor of cytokine signalling
1 - Gallus gallus
Length = 212
Score = 35.1 bits (77), Expect = 2.4
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
+YWG ++ EA L + +LVRDS + +S R + R+ G+F L
Sbjct: 62 FYWGPLSVGEAHAKLQREPVGTYLVRDSSQGNCLFSLSVRMPTGPVSLRISFQEGYFRLK 121
Query: 300 NETFVPAYRLSEHCSA--VNVKTNLFEM---PVKLARPLNRFAK-LDSLQKICR 443
N RL E A N + EM P+ + PL R + + +L+++C+
Sbjct: 122 NWFSDCVVRLLELVVAGTRNNPLHFDEMGGTPLVFSEPLCRSRRTVPTLRELCQ 175
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 35.1 bits (77), Expect = 2.4
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Frame = +3
Query: 114 HGWYWGGITSSE-AEELL-----AGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLH 275
HG GG + AE+LL G D FLVR+S +SF GR H R+
Sbjct: 572 HGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHS 631
Query: 276 -----ANGFFSLDNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPL 401
+ F+ DN F YRL H ++ N FEM +L P+
Sbjct: 632 RQESGSTRFYLTDNLVFDSLYRLICHYRDTPLRCNEFEM--RLGNPV 676
>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 724
Score = 35.1 bits (77), Expect = 2.4
Identities = 19/50 (38%), Positives = 25/50 (50%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLH 260
+H WY G I AEE++ Q D FLVRD ++ + G TLH
Sbjct: 22 SHAWYHGPIPRQRAEEIV--QRDGDFLVRDCVSQPGNYVLTCKTKGPTLH 69
>UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 250
Score = 35.1 bits (77), Expect = 2.4
Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WYWG + + D F+VRDS ++ G R+++ +G +
Sbjct: 6 WYWGEASKEAVNARMRDTEDGTFIVRDSKRFPGEYTLTLMKGGVIKLIRIMYKDGKYGFS 65
Query: 300 NE-TFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRF 410
TF L + ++ ++ VKLA PL+RF
Sbjct: 66 EPLTFKSVIDLVSYYKDRSLAQYNPKLDVKLAHPLSRF 103
>UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF8942,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 431
Score = 34.7 bits (76), Expect = 3.2
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDS 203
W+ G + EAEELL G+ D FLVR+S
Sbjct: 330 WFVGDLKRGEAEELLLGRPDGSFLVRES 357
>UniRef50_Q9UB28 Cluster: Myotactin form B; n=6; cellular
organisms|Rep: Myotactin form B - Caenorhabditis elegans
Length = 4450
Score = 34.7 bits (76), Expect = 3.2
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Frame = -2
Query: 342 NNVQIIYMLAQMFHYLEKKSH-LHVKDVHAVYGQHNEKKRRECVWSHTSLGLKKRCHVGQ 166
N +Q++ + H +EK H LH++ V + + + R + S + KKR H+
Sbjct: 2218 NTLQVLPDAPRAIHLIEKTDHSLHIRWVPPIDPKGYVTQYRVSIVSLDDVNDKKRTHIVN 2277
Query: 165 QATLLLHWT*FHPNTSHDFSLPLET 91
TL + +P TS++ S+ T
Sbjct: 2278 HPTLTYLFEELNPETSYNISISAGT 2302
>UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04559 protein - Schistosoma
japonicum (Blood fluke)
Length = 206
Score = 34.7 bits (76), Expect = 3.2
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDS--YDSRHILCV 230
+H WY G I+ +E+E LL+G FL+R+S Y LCV
Sbjct: 80 DHCWYHGRISRAESESLLSGCPIGSFLIRESDLYSGGLTLCV 121
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 34.7 bits (76), Expect = 3.2
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
WY G I+ +AE LL + +LVR+S S+H +S R +H +L
Sbjct: 410 WYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKL 459
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 34.7 bits (76), Expect = 3.2
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQ-HDNVFLVRDSYDSRHILCVSFRCVGRTLHARLL-HANGF 287
H WY G I+ AEE+L + H FL+R+S S VS + H ++L A+G
Sbjct: 58 HPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGK 117
Query: 288 FSLDNETF 311
+ L E F
Sbjct: 118 YFLWEEKF 125
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 34.7 bits (76), Expect = 3.2
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSLD 299
WY G I EA+ELL Q D FLVR+S+ +S G+ H + + + + +
Sbjct: 460 WYHGAIPRIEAQELLKKQGD--FLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFE 517
Query: 300 NETFVPAYRLSEH 338
F +L +H
Sbjct: 518 GTGFSNIPQLIDH 530
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 34.3 bits (75), Expect = 4.2
Identities = 16/68 (23%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEE-LLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGF 287
N GW++ ++ +AE+ L+ D FL+R ++F+ G+ H R+
Sbjct: 629 NEGWFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTR 688
Query: 288 FSLDNETF 311
+ L T+
Sbjct: 689 YLLGTTTY 696
>UniRef50_A4FSF6 Cluster: Putative uncharacterized protein; n=1;
Thermobia domestica|Rep: Putative uncharacterized
protein - Thermobia domestica (firebrat)
Length = 116
Score = 34.3 bits (75), Expect = 4.2
Identities = 13/20 (65%), Positives = 15/20 (75%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQ 173
+GWYWG I+ EAEE LA Q
Sbjct: 90 YGWYWGPISREEAEEKLANQ 109
>UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21;
Euteleostomi|Rep: Src-like-adapter 2 - Homo sapiens
(Human)
Length = 261
Score = 34.3 bits (75), Expect = 4.2
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEE--LLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANG 284
+HGW + G++ +AEE LL G FL+R+S R +S R R+ H
Sbjct: 91 SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYR- 149
Query: 285 FFSLDN 302
LDN
Sbjct: 150 IHCLDN 155
>UniRef50_Q4SZG7 Cluster: Chromosome 18 SCAF11624, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF11624, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 239
Score = 33.9 bits (74), Expect = 5.5
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL- 296
+YW +T EA LA FL+RDS +S++ R+ N FSL
Sbjct: 108 YYWRSMTMEEAHRALAHAQLGAFLIRDSGQPDVFFTLSYQSEDGPTSIRIQLNNLLFSLC 167
Query: 297 -DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARPLNRFAKLDSLQKIC-RFVIRQTGSS 470
+ TF + L + + + K P + RP + L+++C R +IR G+
Sbjct: 168 GSHRTFASLFSLLAYYTRSSCK---LTTPYRQQRP-------ERLKQMCRRALIRTHGAE 217
Query: 471 N 473
N
Sbjct: 218 N 218
>UniRef50_Q239X8 Cluster: Putative uncharacterized protein; n=2;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 924
Score = 33.9 bits (74), Expect = 5.5
Identities = 21/52 (40%), Positives = 35/52 (67%), Gaps = 1/52 (1%)
Frame = +2
Query: 629 NVII*WKTM*QCVLSTYIKILINKTYLRTTSLIFNN*Y-FLDLSQLNVPTIF 781
NVII KT + +S YIK+ IN Y++ TS+I N+ + F D++ +++ +IF
Sbjct: 755 NVIIIGKTGEKDQISFYIKLFIN--YVQVTSIIQNSIFKFFDITFIDISSIF 804
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 33.9 bits (74), Expect = 5.5
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Frame = +3
Query: 111 NHG--WYWGGITSSEAEELLAG-QHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHAN 281
+HG WY + + AE++L D FLVR + + +SFR G+ H +
Sbjct: 667 HHGKPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEG 726
Query: 282 GFFSLDNETF 311
F++ N F
Sbjct: 727 RLFTIGNAQF 736
>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
Protein vav-3 - Homo sapiens (Human)
Length = 847
Score = 33.9 bits (74), Expect = 5.5
Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 1/94 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL- 296
WY G + +AE L + ++ +LVR +S + H ++L +GFF +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 297 DNETFVPAYRLSEHCSAVNVKTNLFEMPVKLARP 398
+N F L E+ ++K + L P
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFP 765
>UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol
polyphosphate 5- phosphatase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to inositol
polyphosphate 5- phosphatase - Ornithorhynchus anatinus
Length = 1019
Score = 33.5 bits (73), Expect = 7.3
Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
Frame = +3
Query: 114 HGWYWGGITSSEAEELLAGQ-HDNVFLVR--DSYDSRHILCVSF-RCV 245
H W G IT S+AEELL+ D FLVR +S + LCV + CV
Sbjct: 3 HCWNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCVLYHNCV 50
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 33.5 bits (73), Expect = 7.3
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = +3
Query: 117 GWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
GWY G IT EAE L + FLVR+ ++ +S + +H R+
Sbjct: 1315 GWYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMRI 1365
>UniRef50_UPI000049929A Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 511
Score = 33.1 bits (72), Expect = 9.6
Identities = 14/51 (27%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVR-DSYDSRHILCVSFRCVGRTLHARL 269
W++ T +++ L G+ D FL+R + D ++ ++ R G+T H+R+
Sbjct: 409 WFFNTFTKDQSQAQLEGRVDGTFLIRISTTDPKYPFTLTKRTNGKTTHSRI 459
>UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X).; n=1; Takifugu
rubripes|Rep: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X). - Takifugu rubripes
Length = 266
Score = 33.1 bits (72), Expect = 9.6
Identities = 20/47 (42%), Positives = 26/47 (55%)
Frame = +3
Query: 120 WYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLH 260
W+ G IT AEELLA + FL+R S +SR +S+R R H
Sbjct: 23 WFHGIITRKAAEELLAPRPRGCFLIRVS-ESRAGYTLSYRAEDRCKH 68
>UniRef50_UPI000065EF23 Cluster: Homolog of Homo sapiens
"KARP-1-binding protein; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "KARP-1-binding protein -
Takifugu rubripes
Length = 1376
Score = 33.1 bits (72), Expect = 9.6
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Frame = -1
Query: 355 TLTAEQCSDNLYAGTNVSLSREKKPFACKRRACSVRPTQRKETQRMCLESY----ESRTK 188
+++A S+ T+ S SR A + S PT+ K T RM S E++T+
Sbjct: 1023 SISARSDSECTVTRTSTSSSRMSAETALRLGLRSSTPTENKLTPRMRANSVSKLNETKTR 1082
Query: 187 KTLS--CWPASNSSASLDVIPPQY 122
T S C P +SS+ +PP+Y
Sbjct: 1083 TTTSGYCSPTVSSSSRWRRLPPEY 1106
>UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 4
SCAF14752, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 721
Score = 33.1 bits (72), Expect = 9.6
Identities = 20/53 (37%), Positives = 26/53 (49%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
+HGWY G I +E L+ D FLVRDS S ++ R LH R+
Sbjct: 34 SHGWYHGHIPREVSETLVLRNGD--FLVRDSLTSVGDFVLTCRWDNEALHFRI 84
>UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio
rerio|Rep: SH2 domain containing 3C - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 635
Score = 33.1 bits (72), Expect = 9.6
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +3
Query: 81 KKIKFQEAN*N-HGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTL 257
K++K N + HGWY G I +E L+ Q + FL+RDS S ++ R + L
Sbjct: 36 KELKLSSCNLSSHGWYHGRIPWEVSESLV--QQEGDFLIRDSLSSIGDYVLTCRWNQKAL 93
Query: 258 H 260
H
Sbjct: 94 H 94
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 33.1 bits (72), Expect = 9.6
Identities = 17/53 (32%), Positives = 29/53 (54%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
N WY G I+ ++AE LL + +LVR+S S++ +S + +H +L
Sbjct: 343 NQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKL 395
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 33.1 bits (72), Expect = 9.6
Identities = 18/56 (32%), Positives = 29/56 (51%)
Frame = +3
Query: 129 GGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARLLHANGFFSL 296
G + +EAE+ G+ D FLVR+S + +S R T H ++ + +G F L
Sbjct: 663 GKMDRTEAEQETMGRSDGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCL 718
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 33.1 bits (72), Expect = 9.6
Identities = 17/53 (32%), Positives = 29/53 (54%)
Frame = +3
Query: 111 NHGWYWGGITSSEAEELLAGQHDNVFLVRDSYDSRHILCVSFRCVGRTLHARL 269
N WY G I+ ++AE LL + +LVR+S S++ +S + +H +L
Sbjct: 377 NQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKL 429
>UniRef50_Q6CWY2 Cluster: Similarities with sp|P39943 Saccharomyces
cerevisiae YER028c; n=1; Kluyveromyces lactis|Rep:
Similarities with sp|P39943 Saccharomyces cerevisiae
YER028c - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 239
Score = 33.1 bits (72), Expect = 9.6
Identities = 16/51 (31%), Positives = 28/51 (54%)
Frame = -1
Query: 289 KKPFACKRRACSVRPTQRKETQRMCLESYESRTKKTLSCWPASNSSASLDV 137
+KPFAC C R ++ E +R ++SR +K + P S SS+ +++
Sbjct: 37 EKPFACTVPGCPKRFSRNDELKRHIKTHFKSRKRKPRTIRPKSRSSSQVNL 87
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 789,034,987
Number of Sequences: 1657284
Number of extensions: 16103167
Number of successful extensions: 32303
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 31131
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32269
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 79112361923
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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