BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fdpeP01_F_E21 (877 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P33993 Cluster: DNA replication licensing factor MCM7; ... 281 2e-74 UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n... 170 3e-41 UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep:... 161 3e-38 UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7, ... 143 6e-33 UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium ... 132 8e-30 UniRef50_P38132 Cluster: DNA replication licensing factor CDC47;... 124 2e-27 UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor... 118 1e-25 UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota... 117 3e-25 UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, wh... 113 4e-24 UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 113 7e-24 UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7 homol... 109 7e-23 UniRef50_Q5DG64 Cluster: SJCHGC09554 protein; n=1; Schistosoma j... 109 1e-22 UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7... 105 2e-21 UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47... 95 2e-18 UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n... 71 5e-11 UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/... 65 2e-09 UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;... 65 3e-09 UniRef50_Q4Q826 Cluster: DNA replication licensing factor, putat... 64 3e-09 UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6; ... 63 1e-08 UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mc... 62 2e-08 UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 62 2e-08 UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 62 2e-08 UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08 UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM re... 61 3e-08 UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-l... 61 4e-08 UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1; ... 61 4e-08 UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=... 60 1e-07 UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lambli... 60 1e-07 UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum lac... 58 2e-07 UniRef50_P53091 Cluster: DNA replication licensing factor MCM6; ... 58 4e-07 UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome s... 57 5e-07 UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7 ... 56 9e-07 UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1; Haloqu... 56 2e-06 UniRef50_P49731 Cluster: DNA replication licensing factor mcm6; ... 56 2e-06 UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium ... 55 3e-06 UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1; Natron... 54 4e-06 UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta t... 54 4e-06 UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lambl... 54 5e-06 UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6, ... 54 6e-06 UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase, minich... 54 6e-06 UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;... 53 8e-06 UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia b... 53 1e-05 UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1; ... 52 1e-05 UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Re... 52 1e-05 UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus tropica... 52 3e-05 UniRef50_UPI000049A27A Cluster: DNA replication licensing factor... 51 3e-05 UniRef50_Q00Y49 Cluster: DNA replication licensing factor, MCM5 ... 51 3e-05 UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7; ... 51 3e-05 UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermu... 51 3e-05 UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 51 4e-05 UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM... 50 8e-05 UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of str... 50 8e-05 UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6 ... 50 8e-05 UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus lu... 50 1e-04 UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, wh... 50 1e-04 UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489... 50 1e-04 UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;... 38 1e-04 UniRef50_Q979U9 Cluster: DNA replication initiator; n=4; Thermop... 49 1e-04 UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing fact... 49 1e-04 UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole geno... 49 2e-04 UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, wh... 48 3e-04 UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8... 48 3e-04 UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing fac... 48 3e-04 UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8; ... 48 3e-04 UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 48 4e-04 UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep:... 48 4e-04 UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14;... 47 5e-04 UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 46 0.001 UniRef50_Q5K7N5 Cluster: DNA unwinding-related protein, putative... 46 0.001 UniRef50_UPI000049880B Cluster: DNA replication licensing factor... 45 0.002 UniRef50_Q5V011 Cluster: MCM / cell division control protein 21;... 45 0.002 UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance pr... 45 0.002 UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=... 45 0.003 UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/... 45 0.003 UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3 h... 44 0.004 UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1; Te... 44 0.005 UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2; ... 44 0.005 UniRef50_Q5V814 Cluster: MCM / cell division control protein 21;... 44 0.007 UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome s... 43 0.009 UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured hal... 42 0.016 UniRef50_Q5JEJ0 Cluster: DNA replication licensing factor, MCM2/... 42 0.021 UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2... 42 0.027 UniRef50_Q4SLL7 Cluster: Chromosome 15 SCAF14556, whole genome s... 41 0.036 UniRef50_P30666 Cluster: DNA replication licensing factor mcm3; ... 41 0.036 UniRef50_UPI0000D56719 Cluster: PREDICTED: similar to minichromo... 41 0.047 UniRef50_Q4QJG9 Cluster: DNA replication licensing factor, putat... 41 0.047 UniRef50_Q389T6 Cluster: Minichromosome maintenance (MCM) comple... 40 0.083 UniRef50_P33991 Cluster: DNA replication licensing factor MCM4; ... 40 0.083 UniRef50_P30665 Cluster: Cell division control protein 54; n=18;... 40 0.11 UniRef50_Q22D74 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14 UniRef50_P49736 Cluster: DNA replication licensing factor MCM2; ... 39 0.14 UniRef50_Q9LPD9 Cluster: T12C22.19 protein; n=18; Eukaryota|Rep:... 39 0.19 UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 l... 39 0.19 UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1; ... 39 0.19 UniRef50_Q019K0 Cluster: DNA replication licensing factor, MCM5 ... 38 0.25 UniRef50_Q5KDY4 Cluster: DNA replication licensing factor cdc19 ... 38 0.25 UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whol... 38 0.33 UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 38 0.33 UniRef50_A5K611 Cluster: DNA replication licensing factor, putat... 38 0.44 UniRef50_Q8SSE5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 38 0.44 UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2 ... 38 0.44 UniRef50_P29469 Cluster: DNA replication licensing factor MCM2; ... 38 0.44 UniRef50_Q5HCB0 Cluster: Putative uncharacterized protein Erum06... 37 0.58 UniRef50_A7S8B1 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 37 0.58 UniRef50_UPI00006CFD9E Cluster: conserved hypothetical protein; ... 37 0.77 UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1; ... 37 0.77 UniRef50_P24279 Cluster: DNA replication licensing factor MCM3; ... 37 0.77 UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1; Te... 36 1.0 UniRef50_Q98RT4 Cluster: Putative uncharacterized protein orf670... 36 1.0 UniRef50_A1CSW6 Cluster: DNA replication licensing factor MCM4; ... 36 1.0 UniRef50_Q8I1S4 Cluster: DNA replication licensing factor, putat... 36 1.4 UniRef50_Q4Q8I2 Cluster: Minichromosome maintenance (MCM) comple... 36 1.8 UniRef50_A0BNH6 Cluster: Chromosome undetermined scaffold_118, w... 36 1.8 UniRef50_UPI0000499A20 Cluster: hypothetical protein 53.t00045; ... 35 2.4 UniRef50_A3DIH5 Cluster: Radical SAM; n=1; Clostridium thermocel... 35 2.4 UniRef50_A5AY09 Cluster: Putative uncharacterized protein; n=6; ... 35 2.4 UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4 UniRef50_Q4T0H4 Cluster: Chromosome undetermined SCAF11052, whol... 35 3.1 UniRef50_A0YYA0 Cluster: Putative uncharacterized protein; n=2; ... 35 3.1 UniRef50_Q5CNK7 Cluster: DNA replication licensing factor MCM2; ... 35 3.1 UniRef50_Q54H83 Cluster: Putative uncharacterized protein; n=1; ... 35 3.1 UniRef50_Q9A7Q4 Cluster: TonB-dependent receptor; n=4; Proteobac... 34 4.1 UniRef50_Q6JT33 Cluster: NADH-ubiquinone oxidoreductase chain 1;... 34 4.1 UniRef50_A7TQN0 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1 UniRef50_Q8ILG6 Cluster: Coatamer protein, beta subunit, putativ... 34 5.5 UniRef50_Q5TN00 Cluster: ENSANGP00000028786; n=4; Culicidae|Rep:... 34 5.5 UniRef50_Q54LI2 Cluster: MCM family protein; n=2; Eukaryota|Rep:... 34 5.5 UniRef50_Q8PGT4 Cluster: Transcriptional regulator; n=6; Xanthom... 33 7.2 UniRef50_Q67PC7 Cluster: DNA topoisomerase; n=1; Symbiobacterium... 33 7.2 UniRef50_Q8GQC7 Cluster: NtrC; n=5; Leptospira|Rep: NtrC - Lepto... 33 7.2 UniRef50_Q6KD52 Cluster: Putative uncharacterized protein; n=4; ... 33 7.2 UniRef50_A7HCY8 Cluster: Heavy metal efflux pump, CzcA family; n... 33 7.2 UniRef50_A5VI77 Cluster: YidE/YbjL duplication; n=3; Lactobacill... 33 7.2 UniRef50_Q9VDT2 Cluster: CG17186-PA; n=1; Drosophila melanogaste... 33 7.2 UniRef50_Q7RI91 Cluster: Replication origin activator 2-related;... 33 7.2 UniRef50_Q16ZI3 Cluster: DNA replication licensing factor MCM1; ... 33 7.2 UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 33 7.2 UniRef50_A0DPP4 Cluster: Chromosome undetermined scaffold_59, wh... 33 7.2 UniRef50_UPI00004994EB Cluster: DNA replication licensing factor... 33 9.5 UniRef50_Q91GJ2 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5 UniRef50_Q18YV3 Cluster: LPXTG-motif cell wall anchor domain pre... 33 9.5 UniRef50_Q54S44 Cluster: Putative uncharacterized protein; n=2; ... 33 9.5 UniRef50_A7F6V0 Cluster: Putative uncharacterized protein; n=2; ... 33 9.5 UniRef50_A3CTI4 Cluster: CRISPR-associated protein Cas1; n=1; Me... 33 9.5 UniRef50_P20929 Cluster: Nebulin; n=63; Euteleostomi|Rep: Nebuli... 33 9.5 >UniRef50_P33993 Cluster: DNA replication licensing factor MCM7; n=52; Eukaryota|Rep: DNA replication licensing factor MCM7 - Homo sapiens (Human) Length = 719 Score = 281 bits (688), Expect = 2e-74 Identities = 128/237 (54%), Positives = 178/237 (75%) Frame = +2 Query: 137 MAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE 316 MA++DY +KE K F +F Q D+ GKK FKY QL ++AHREQ+A VDLDD+ E + Sbjct: 1 MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP 60 Query: 317 DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEM 496 +L +++ +N RRY + +D V E+LP YK +EVV KD LDVYIEHR+M+E R+ R PG + Sbjct: 61 ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRS-RDPGMV 119 Query: 497 RDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVV 676 R P+N+YP EL+RRFE+YF+ S++K IREV+A+ +GKLVTVRGIVTR ++VKP +VV Sbjct: 120 RSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVV 179 Query: 677 ATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 ATY+C CGAETYQP+++ F P C + +C+ N++ G+L+LQTRGSRF KF+ ++ Sbjct: 180 ATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 236 >UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n=6; Dikarya|Rep: ATP dependent DNA helicase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 788 Score = 170 bits (414), Expect = 3e-41 Identities = 84/213 (39%), Positives = 128/213 (60%), Gaps = 2/213 (0%) Frame = +2 Query: 215 GKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLT--EAVKQNTRRYTNMVSDVVYEM 388 G+ FKY L +VA+R + +DL DL + DL+ ++ NTRRY + SDV+ ++ Sbjct: 78 GRTKFKYLRMLREVANRRREDIVIDLKDLKRHSNDLSLLHNIQNNTRRYIQLFSDVIDKI 137 Query: 389 LPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLST 568 +P + D LD+ ++ R + A+ GE +PPEL+RR+ VYF+ L + Sbjct: 138 MPPPDNEVDYTDDVLDLIMQQRREMNAQVEA--GERNADAGMFPPELMRRYNVYFRPLRS 195 Query: 569 SKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPP 748 + +R V+ H+GKL+TVRGIVTR ++VKPLL+V Y+C +CG E +Q + F P Sbjct: 196 DDVLAVRAVRGAHLGKLITVRGIVTRVSEVKPLLIVNAYTCDSCGNEIFQEITQKHFAPL 255 Query: 749 PACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 C +D C N+T GQLH+QTR SRF+ F+ ++ Sbjct: 256 TVCPSDVCVRNQTNGQLHMQTRASRFRPFQEVK 288 >UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep: Protein PROLIFERA - Arabidopsis thaliana (Mouse-ear cress) Length = 716 Score = 161 bits (390), Expect = 3e-38 Identities = 97/240 (40%), Positives = 132/240 (55%), Gaps = 3/240 (1%) Frame = +2 Query: 137 MAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE 316 M D+ DK K F +F D G+ KY E L +V++R+ A +VDLDDL + Sbjct: 1 MKDHDFDGDKGLAKGFLENFA--DANGRS--KYMEILQEVSNRKIRAIQVDLDDLFNYKD 56 Query: 317 DLTE---AVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIP 487 + E + +NTRRY ++ S V E+LP+ E D D+ + R A + Sbjct: 57 ESEEFLGRLTENTRRYVSIFSAAVDELLPEPT--EAFPDDDHDILMTQR----ADDGTDN 110 Query: 488 GEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPL 667 ++ DP + P E+ R +EVYFK S + IREVKA HIG+LV + GIVTRC+DVKPL Sbjct: 111 PDVSDPHQQIPSEIKRYYEVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPL 170 Query: 668 LVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 + VA Y+C CG E YQ V + F P C + CRLN AG LQ R S+F KF+ + Sbjct: 171 MAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNSKAGNPILQLRASKFLKFQEAK 230 >UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7, putative; n=10; Ascomycota|Rep: DNA replication licensing factor Mcm7, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 854 Score = 143 bits (346), Expect = 6e-33 Identities = 85/226 (37%), Positives = 129/226 (57%), Gaps = 20/226 (8%) Frame = +2 Query: 230 KYAEQLTKVAHREQIAFEVDLDDL----HEMNED----LTEAVKQNTRRYTNMVSDVVYE 385 KY + L +A RE+ ++LDDL + ED L E++++NT+RY ++ SD V Sbjct: 82 KYMQILQDIADRERSNVLIELDDLATFEKSLPEDTDLKLVESIQRNTKRYIDVFSDAVDA 141 Query: 386 MLPDYKFKEVVAKDS-LDVYIEHRIML-EARNHRIPGEMRDPR--NRYPPELIRRFEVYF 553 ++P + KE+ KD LDV + R EA +M + +PPEL RR+ + F Sbjct: 142 VMPK-ETKEITFKDDVLDVIMSQREKRNEAMAMAAEADMDAAAAPSMFPPELTRRYTLNF 200 Query: 554 KDLSTS--------KSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE 709 K L+ S K++ +R V+AEH+G L+TVRGI TR +DVKP + + Y+C CG E Sbjct: 201 KPLTPSGSSSDRYSKALAVRNVRAEHLGSLITVRGITTRVSDVKPSVQINAYTCDRCGCE 260 Query: 710 TYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 +QPV QF P C +++C+ N + GQL L TR S+F F+ ++ Sbjct: 261 VFQPVTTKQFLPMTECLSEECKQNNSKGQLFLSTRASKFVPFQEVK 306 >UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium discoideum AX4|Rep: MCM family protein - Dictyostelium discoideum AX4 Length = 789 Score = 132 bits (320), Expect = 8e-30 Identities = 86/261 (32%), Positives = 138/261 (52%), Gaps = 28/261 (10%) Frame = +2 Query: 149 DYTADKESFKNFFVDFCQTDDEGKKYF-KYAEQLTKVAHREQIAFEVDLDDLHEMNEDLT 325 DY ++KE K+F F TD+ F KY E + ++ R++ F+++LDD++ N DL Sbjct: 47 DYLSEKEKCKDFLNFFKCTDNGNIGGFEKYVEMMKEITQRKRKNFDIELDDVYNFNRDLV 106 Query: 326 --EAVKQNTRRYTNMVSDVVYEML--PDYKFKEVVA-----------KDSLDVYIEHRIM 460 E+++ T Y + + + E++ PD K+ Y ++ Sbjct: 107 FVESIENQTSTYLRLFTYALDELIPPPDLSSTRSAMGFNNDDGFDKNKEDQKFYQNSDMV 166 Query: 461 LEA-RNHRIPGE-MRDPRNR---------YPPELIRRFEVYFKDLSTSKSVPIREVKAEH 607 L+ + RI + +NR +P E+IRRFE++F +PIR +++E Sbjct: 167 LDLLASQRIQRKKFLQEQNRLDLDSNEFDFPQEIIRRFELHFIPRKGKSIIPIRLIRSEL 226 Query: 608 IGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDC-RLNK 784 IG+LVT G+VTR TDVKPL+V++ Y+C CGAE +Q + + +F P C + C K Sbjct: 227 IGRLVTFSGVVTRVTDVKPLVVISLYTCDICGAEIFQEITSREFMPLFQCKSKQCTEGGK 286 Query: 785 TAGQLHLQTRGSRFQKFRSLR 847 AG L LQTRGS+F KF+ ++ Sbjct: 287 QAGNLTLQTRGSKFVKFQEIK 307 >UniRef50_P38132 Cluster: DNA replication licensing factor CDC47; n=21; Eukaryota|Rep: DNA replication licensing factor CDC47 - Saccharomyces cerevisiae (Baker's yeast) Length = 845 Score = 124 bits (300), Expect = 2e-27 Identities = 87/254 (34%), Positives = 126/254 (49%), Gaps = 48/254 (18%) Frame = +2 Query: 230 KYAEQLTKVAHREQIAFEVDLDD-LHEMNE---------DLTEAVKQNTRRYTNMVSDVV 379 KY L KVA+RE + +DLDD L NE DL A++QN +T + + Sbjct: 62 KYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAI 121 Query: 380 YEMLPDYKFKEVVAKDS-LDVYIEHRI-----MLEARNHRIPGE---------------- 493 +P KE+ KD LDV + R ML R + I E Sbjct: 122 DNNMP-LPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180 Query: 494 ----MRDPRNRYPPELIRRFEVYFKDLS------------TSKSVPIREVKAEHIGKLVT 625 + D +PP L RR+ +YFK LS +SK + +R++K + +G+L+T Sbjct: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240 Query: 626 VRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHL 805 VRGI+TR +DVKP + V Y+C CG E +Q V + FTP CT+++C N+T GQL + Sbjct: 241 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM 300 Query: 806 QTRGSRFQKFRSLR 847 TR S+F F+ + Sbjct: 301 STRASKFSAFQECK 314 >UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA replication licensing factor - Entamoeba histolytica HM-1:IMSS Length = 690 Score = 118 bits (285), Expect = 1e-25 Identities = 73/235 (31%), Positives = 116/235 (49%), Gaps = 6/235 (2%) Frame = +2 Query: 161 DKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNED------L 322 DK + ++F + +D G Y EQ+ F D+ D +N++ + Sbjct: 29 DKITIEHFLTTYVLSD--GSTYKSRLEQINIQRDGNFTIFLDDVKDYLSLNDNQIKDKKI 86 Query: 323 TEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRD 502 + ++ N RY N+ +V+Y +LP + + DS+DV + ++ ++ Sbjct: 87 LDRIESNAARYLNIFKEVIYTLLPSRVGLDPSSLDSVDV-----LTIQRETKKL------ 135 Query: 503 PRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVAT 682 +P EL +FE + + + PIRE++AE IGKLV V+GIVTR TDV+PL V T Sbjct: 136 ---SFPLELKAKFETFIRPRKNQEITPIRELRAEKIGKLVRVKGIVTRATDVRPLARVIT 192 Query: 683 YSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 YSC CG E YQ + +F P C + C+ G L +Q R S+F K + +R Sbjct: 193 YSCEQCGNELYQTIIGNRFLPQYKCPSKTCQKGNKTGTLLMQPRASKFVKIQEIR 247 >UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota|Rep: MCM2/3/5 family protein - Tetrahymena thermophila SB210 Length = 1681 Score = 117 bits (282), Expect = 3e-25 Identities = 68/220 (30%), Positives = 119/220 (54%), Gaps = 10/220 (4%) Frame = +2 Query: 230 KYAEQLTKVAHREQIAFEVDLDDLHEM-----NEDLTEAVKQNTRRYTNMVSDVVYEMLP 394 KY L +VA+ + ++ ++DL E + L +A+++NT R+ +++S V ++P Sbjct: 971 KYMNLLQRVANNQDSRVDILMEDLEEYFKSEKDRPLIDAIQRNTSRFVDILSKVCDTVMP 1030 Query: 395 DYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMR---DPRNRYPPELIRRFEVYF--KD 559 + V ++ +I+ + R + G+ + +NR P L R+F+++ Sbjct: 1031 A---RNVPMTSDEEMENMQQILNDQRMSNMEGDQNKDDNVKNRLNPLLNRKFQLFIIRGP 1087 Query: 560 LSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQF 739 S K PIR +K+E IG LVT++ IV R +DVKP++ VA Y C CG E YQ V + F Sbjct: 1088 DSKQKITPIRNLKSEDIGGLVTIKAIVIRTSDVKPMMQVACYICDTCGCELYQTVSSKTF 1147 Query: 740 TPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRST 859 TP C ++ C+ N+T G++ + S FQ ++ +R + T Sbjct: 1148 TPLQECISNTCKTNRTKGKVVISPSSSVFQAYQEIRVQET 1187 >UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_43, whole genome shotgun sequence - Paramecium tetraurelia Length = 745 Score = 113 bits (273), Expect = 4e-24 Identities = 70/235 (29%), Positives = 122/235 (51%), Gaps = 9/235 (3%) Frame = +2 Query: 149 DYTADKESFKNFFVDFCQTD----DEGKKYFKYAEQLTKVAHREQIAFEVDLDDL-HEMN 313 +Y ++ S F +F D KY +L ++A+R+ ++ ++DL + N Sbjct: 14 EYASELSSLSEFLAEFRDNSIVEIDNTYGQRKYMIELQRIANRQTNRIDIYVEDLEYFFN 73 Query: 314 E--DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIP 487 + D +K NT Y ++ D ++P + ++ + + D++ E + +N Sbjct: 74 DRIDFVNKIKTNTLSYQRLLYDACDTLMPQ-QTRDF--EQNFDLFDEEINVQRQQNMEQD 130 Query: 488 GEMRDPRNRYPPELIRRFEVYF-KDLSTSKSV-PIREVKAEHIGKLVTVRGIVTRCTDVK 661 G + + R PPELIRR++++ + T + V IR +KA+ IG L+T++ +V R ++V+ Sbjct: 131 GN-NNHQKRLPPELIRRYQLFIIRGPQTKQQVMAIRNLKAQLIGSLITIKAMVVRTSEVR 189 Query: 662 PLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRF 826 P ++VA +SC ACG E YQ V FTP C +D CR NK G+L S+F Sbjct: 190 PQIIVACFSCDACGYENYQTVHGKTFTPMLDCASDKCRDNKVRGRLIFNHGSSKF 244 >UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM7; n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM7 - Encephalitozoon cuniculi Length = 694 Score = 113 bits (271), Expect = 7e-24 Identities = 75/233 (32%), Positives = 118/233 (50%), Gaps = 1/233 (0%) Frame = +2 Query: 149 DYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNED-LT 325 DY ADK+ F + F + D E YA +L + + E+D++D+ +E L Sbjct: 15 DYQADKDRLSKFLL-FHEEDGE----LTYANRLREAGG----SVEIDMEDIAVYDETGLV 65 Query: 326 EAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDP 505 ++ N Y N++ VV E+L + + ++ D++ HR+ R P + Sbjct: 66 GRIEGNAMSYINLLYTVVDEILLEGG-DVPMGEEPEDIFFYHRV--SRLKERFPE--KSA 120 Query: 506 RNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATY 685 +P L+RR+ + K S+ +R +K+ HIG LV V G+VT+ + VKP + VATY Sbjct: 121 LEVFPSFLLRRYSLVLKPRRNSRVYSVRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATY 180 Query: 686 SCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSL 844 C CGAETYQ V F C ++ CR+ G L L TRGS+F K +++ Sbjct: 181 VCEGCGAETYQEVDGDVFDLLEECGSEKCRIRNVRGTLVLVTRGSKFIKHQTV 233 >UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7 homologue; n=1; Ostreococcus tauri|Rep: Replication licensing factor MCM7 homologue - Ostreococcus tauri Length = 354 Score = 109 bits (263), Expect = 7e-23 Identities = 68/243 (27%), Positives = 118/243 (48%), Gaps = 5/243 (2%) Frame = +2 Query: 134 IMAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMN 313 +M+ Y D+E + F +T G Y + ++ R+ + +++L + E + Sbjct: 44 LMSEEVYAHDRELIRGFL----ETFKSGAAKPLYIIAMQEIIDRQSCSMQIELQHVKEFS 99 Query: 314 E----DLTEAVKQNTRRYTNMVSDVVYEMLPDY-KFKEVVAKDSLDVYIEHRIMLEARNH 478 E L V N +RY+ + ++ + +++ + + D+ D+ + H Sbjct: 100 EAERDQLVRRVVSNCKRYSTIFAEEIDKIMARMIESSSMHPDDTADIVLRHHFGDHRNGS 159 Query: 479 RIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDV 658 PG +R R F+V+FK + + + +RE++A+ IGK VT +G+ TR TDV Sbjct: 160 AAPGSLR-----------RHFDVFFKPATGTTPIKMREIRAKMIGKYVTFKGMCTRLTDV 208 Query: 659 KPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFR 838 KPL+ VA Y+C CG E +Q V QF P C + C N L ++TR S+F K++ Sbjct: 209 KPLMEVACYTCEGCGQEYFQEVTDTQFIPIQFCQSQTCNKNFA---LFIETRASKFAKYQ 265 Query: 839 SLR 847 LR Sbjct: 266 ELR 268 >UniRef50_Q5DG64 Cluster: SJCHGC09554 protein; n=1; Schistosoma japonicum|Rep: SJCHGC09554 protein - Schistosoma japonicum (Blood fluke) Length = 135 Score = 109 bits (261), Expect = 1e-22 Identities = 49/98 (50%), Positives = 65/98 (66%) Frame = +2 Query: 485 PGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKP 664 P M + R+R+PPEL+RRFEVYF S K + +R V A IG L+ VRG+VTR T+VKP Sbjct: 23 PVNMAEVRSRFPPELLRRFEVYFCGRSDKKPLSVRNVLASSIGHLIQVRGVVTRATEVKP 82 Query: 665 LLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRL 778 L+ ATY+C CGAE+YQ + F P AC+ C++ Sbjct: 83 LITTATYTCDRCGAESYQEINNPTFMPLIACSTAVCKM 120 >UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7p; n=2; Cryptosporidium|Rep: Minichromosome maintenance protein mcm7p - Cryptosporidium hominis Length = 857 Score = 105 bits (251), Expect = 2e-21 Identities = 65/221 (29%), Positives = 104/221 (47%), Gaps = 5/221 (2%) Frame = +2 Query: 200 QTDDEGK--KYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSD 373 +T+ EG K+ KY + L +++RE+ +++DD+ + + Y N+V Sbjct: 50 ETEKEGSIWKHKKYMKSLQSISNREKNVLYIEVDDILSFGK-----YENKVTEYNNLVHS 104 Query: 374 VVYEMLPDYKFKEVVAKDSLDVYIEHRIM---LEARNHRIPGEMRDPRNRYPPELIRRFE 544 ++ + + A + L V I+ LE N+ E N P L FE Sbjct: 105 ILSNTKRYVQLIYIAADNCLPVPTRTNIIDFKLEEMNNTKRSESMKTCN-VPAYLRSNFE 163 Query: 545 VYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPV 724 VY K P+REV+AE++G V V IVTR ++VKP + V Y+C CG+ +Q V Sbjct: 164 VYIKASKRMPITPLREVRAEYVGGYVQVNCIVTRVSNVKPRMQVVNYTCEVCGSSIWQSV 223 Query: 725 RALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 + P C + C+ NK G L + S+F KF+ +R Sbjct: 224 EGTNYMPLSDCESSQCKNNKRTGNLKCNIKESKFTKFQEIR 264 >UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47 homolog) (Minichromosome maintenance (MCM) complex subunit, putative); n=6; Trypanosomatidae|Rep: DNA replication licensing factor (CDC47 homolog) (Minichromosome maintenance (MCM) complex subunit, putative) - Leishmania major Length = 725 Score = 95.5 bits (227), Expect = 2e-18 Identities = 73/235 (31%), Positives = 113/235 (48%), Gaps = 2/235 (0%) Frame = +2 Query: 149 DYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE-DLT 325 +Y D++ K F +F D G+ KY Q +A R+ I F + LDD+ + L Sbjct: 19 NYINDRDVCKRFLEEF--RDSTGQA--KYVIQAHHIAQRQSIVFSIFLDDVAGFGQLHLA 74 Query: 326 EAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDP 505 + V+ N Y + VV ++P + VV D +D ++++EA R+ G+ Sbjct: 75 QRVQMNVVGYMEELYRVVDSIIP--QTDRVV--DMVD-----QLIMEA---RMSGQ---- 118 Query: 506 RNRYPPELIRRFEVYFKDLS-TSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVAT 682 P L RR+E+ LS S +P+RE+K IG L +RGI T V+P L + Sbjct: 119 --ELPALLTRRYELKIHPLSEDSVPIPLRELKGGKIGTLTVLRGICIAATAVRPKLSMLV 176 Query: 683 YSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 C C T+Q V + TP C + C+LN G+L Q + S+F K++ LR Sbjct: 177 SVCEVCAETTFQQVIGDRLTPLQVCQSQRCKLNNAVGRLLAQNKASKFMKYQELR 231 >UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n=1; Babesia bovis|Rep: ATP dependent DNA helicase, putative - Babesia bovis Length = 765 Score = 70.5 bits (165), Expect = 5e-11 Identities = 58/215 (26%), Positives = 101/215 (46%), Gaps = 9/215 (4%) Frame = +2 Query: 230 KYAEQLTKVAHREQIAFEVDLDD-----LHEMNE-DLTEAVKQNTRRYTNMV---SDVVY 382 +Y QL ++ +R+ V LDD L + NE + E + N RY ++ +D Sbjct: 49 RYMNQLQEIKNRKSNILRVYLDDIRQHFLKDTNEHQVYEGLMLNAYRYLELMYAAADACL 108 Query: 383 EMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDL 562 E + + + S + ++ +L++ + E R +++ P L FE++ Sbjct: 109 EGIERNVEEHDPYRLSPGRHNQNPDVLDSVDEL--RERRMKQSKLPVYLYSNFEIWLIPG 166 Query: 563 STSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFT 742 S+ + ++ V A++IG L + VTR +KP + VATY C +C + TY+ ++ F Sbjct: 167 SSDSVMKMKTVNADYIGCLSLIEVDVTRVGLLKPRVQVATYECDSCHSHTYKAIQGPNFL 226 Query: 743 PPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 P C D N T G L R S+F K++ LR Sbjct: 227 PITDC-VDCITRNNTRGTLKFHPRLSKFDKYQELR 260 >UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/3/5 family; n=3; Thermococcus kodakarensis KOD1|Rep: DNA replication licensing factor, MCM2/3/5 family - Pyrococcus kodakaraensis (Thermococcus kodakaraensis) Length = 1157 Score = 65.3 bits (152), Expect = 2e-09 Identities = 41/119 (34%), Positives = 64/119 (53%), Gaps = 1/119 (0%) Frame = +2 Query: 512 RYPPELIRR-FEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYS 688 R PP L+ R F+V+ + + K++ ++E+ +EHI KL+ V GI+TR ++VKP + A + Sbjct: 80 REPPLLVEREFKVHARFYNLPKTLLVKELGSEHINKLIQVEGIITRVSEVKPFVEKAVFV 139 Query: 689 CSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRSTRP 865 C CG E + R + PA D C + + L SRF F+S R + RP Sbjct: 140 CRDCGNEMVRLQRPYENLVKPA-KCDAC----GSRNIELDVDKSRFLNFQSFRLQD-RP 192 >UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative; n=2; Theileria|Rep: Replication licensing factor, putative - Theileria annulata Length = 1021 Score = 64.9 bits (151), Expect = 3e-09 Identities = 39/113 (34%), Positives = 58/113 (51%) Frame = +2 Query: 461 LEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIV 640 LE + E+ + NR P R+F + F T P+REVK +G+L+ +RG V Sbjct: 154 LEDVLQNLVNEISNAVNRVP----RKFYLQFLHTPTI-IYPLREVKCFMLGELICIRGQV 208 Query: 641 TRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQL 799 TR +DV+P L+ AT+ C CG V+ ++T P C C LN + +L Sbjct: 209 TRVSDVRPELIRATFRCKTCGTVVTDIVQQFKYTTPTKCPTSSC-LNNSDWEL 260 >UniRef50_Q4Q826 Cluster: DNA replication licensing factor, putative; n=6; Trypanosomatidae|Rep: DNA replication licensing factor, putative - Leishmania major Length = 880 Score = 64.5 bits (150), Expect = 3e-09 Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 3/92 (3%) Frame = +2 Query: 572 KSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPP 751 + + IR ++A +G+L ++G+VTR + V+P L+V + CS CG + + +T PP Sbjct: 153 RCLTIRSLRASLVGQLCAIKGVVTRTSQVRPELLVGVFRCSDCGTGSLPIEQQFHYTEPP 212 Query: 752 ACTADDCRLNKTAGQL---HLQTRGSRFQKFR 838 C C NK QL H QTR +QK R Sbjct: 213 TCRNPQCE-NKNKFQLIPNHPQTRFGDWQKLR 243 >UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6; Thermoproteales|Rep: DNA replication licensing factor - Pyrobaculum aerophilum Length = 680 Score = 62.9 bits (146), Expect = 1e-08 Identities = 39/161 (24%), Positives = 80/161 (49%) Frame = +2 Query: 272 IAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEH 451 ++ E++LD L + +L + ++ + N++ + D+ + K D+ +E Sbjct: 1 MSLEIELDLLRDKFRELVTSNEKISDEVINIIIQRKRSLEVDFHDILMFDKSLADLVVER 60 Query: 452 RIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVR 631 ++ ++ E+ + ++ + ++RF YF+ + SV +R++++E+IG+L+ + Sbjct: 61 PKLVLPEADKVVREIVEEKDPETAKALKRF--YFRVRGSPLSVSLRKLRSEYIGRLIKIE 118 Query: 632 GIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPA 754 GIVTR T K L A Y C+ CG E + PPA Sbjct: 119 GIVTRQTPPKHFLYKALYRCTQCGYEIELLQELERHVEPPA 159 >UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mcm protein - Archaeoglobus fulgidus Length = 698 Score = 62.1 bits (144), Expect = 2e-08 Identities = 28/70 (40%), Positives = 42/70 (60%) Frame = +2 Query: 551 FKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRA 730 F L T++ V IR ++AEHIGK + + GIV + T+V+P +V A ++C CG+ T P Sbjct: 90 FYSLPTARKVLIRNLRAEHIGKFMAIEGIVRKVTEVRPRIVEAAFACLNCGSITMVPQED 149 Query: 731 LQFTPPPACT 760 Q P C+ Sbjct: 150 SQLRQPFECS 159 >UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena thermophila SB210|Rep: MCM2/3/5 family protein - Tetrahymena thermophila SB210 Length = 826 Score = 61.7 bits (143), Expect = 2e-08 Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 551 FKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRA 730 F +L T K IRE+ + IGKL +++G+VTR ++V+P L+ T+ C C +E + Sbjct: 111 FYNLPTEKK--IRELGTQEIGKLNSIKGLVTRSSEVRPELLYGTFICQLCNSEVRDIEQQ 168 Query: 731 LQFTPPPACTADDCRLNKTAGQLHLQTR-GSRFQKFRSLRYRSTRPSPGG 877 ++T P C+ C N T L Q+ S FQK R ++ ST GG Sbjct: 169 FKYTEPKICSNPGCN-NHTKWMLKPQSSVFSDFQKLR-VQEESTDIPAGG 216 >UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomonas vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas vaginalis G3 Length = 754 Score = 61.7 bits (143), Expect = 2e-08 Identities = 54/228 (23%), Positives = 91/228 (39%), Gaps = 1/228 (0%) Frame = +2 Query: 164 KESFKNFFVDFCQT-DDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQ 340 + K F+ F T +EG Y Q K+ E V + L++ + E + + Sbjct: 8 QNQIKARFLTFLNTYKEEGSDELYYHVQFEKMKEEENTTLRVSYEHLYQFDSTFAEIIAE 67 Query: 341 NTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYP 520 N R+ N + L D+ V+A+D + + I G +PR Sbjct: 68 NLYRFYNSL----VAALVDF----VMAQDKM--------------YAIEGRTHNPRP--- 102 Query: 521 PELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 F + D + + +R++K H+G L+ +G VTR +DV+P L+ T+ C C Sbjct: 103 ------FALSITDYNVKSA--LRQIKPSHVGTLIMFQGTVTRISDVQPELLKGTFRCRVC 154 Query: 701 GAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSL 844 G + + Q+T P C C + L T S F F+ + Sbjct: 155 GQDIPNVTQNFQYTEPSVCPNKSC---NNHSRFELLTDRSEFTDFQRI 199 >UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 877 Score = 61.7 bits (143), Expect = 2e-08 Identities = 31/88 (35%), Positives = 55/88 (62%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +R ++A++IG+L+++ G VTR ++V+P L +AT+ C AC A + ++T P C Sbjct: 392 VRALRAKNIGQLLSISGTVTRTSEVRPELSLATFMCQACKAIVPNVEQTFRYTEPTQCPN 451 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 D+C+ N+ A QL + R S F ++ +R Sbjct: 452 DNCQ-NRLAWQLDI--RQSTFVDWQKVR 476 >UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM related protein; n=1; uncultured euryarchaeote Alv-FOS1|Rep: DNA replication licensing factor MCM related protein - uncultured euryarchaeote Alv-FOS1 Length = 682 Score = 61.3 bits (142), Expect = 3e-08 Identities = 32/106 (30%), Positives = 53/106 (50%) Frame = +2 Query: 560 LSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQF 739 +S + + IR+++ HIGK V +RGI+ R ++V+P L + + CS CG Y+ + Sbjct: 88 ISDNFKMEIRKLRTTHIGKFVAIRGIIRRASEVRPKLKIGAFKCSDCGGINYEEQPGNRL 147 Query: 740 TPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRSTRPSPGG 877 P C + C K + HL S F+ F+ + + T S G Sbjct: 148 VYPDKC--EICGKPKGKIKFHLVPEDSVFEDFQVVEVQDTPESLRG 191 >UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-like AAA ATpase; n=3; Cryptosporidium|Rep: DNA replication licensing factor MCM6-like AAA ATpase - Cryptosporidium parvum Iowa II Length = 1055 Score = 60.9 bits (141), Expect = 4e-08 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +R ++ E +GKL ++RG +TR +DV+P L+ A + C CG V+ ++ P C Sbjct: 147 LRTLRCEKLGKLCSLRGTITRTSDVRPELIKACFECEICGCIVDNVVQQFVYSLPSVCPT 206 Query: 764 DDCRLNKTAGQLHLQTRG-SRFQKFRSLRYRSTRPSPG 874 C N+TA QL L+ +QK R ++ +T PG Sbjct: 207 KGCG-NRTAWQLRLENCDFGDWQKLR-IQEHATEIPPG 242 >UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1; Haloarcula marismortui|Rep: Cell division control protein 21 - Haloarcula marismortui (Halobacterium marismortui) Length = 1175 Score = 60.9 bits (141), Expect = 4e-08 Identities = 34/96 (35%), Positives = 50/96 (52%) Frame = +2 Query: 572 KSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPP 751 +S IR+++ EH G LV VRGI+ + TDV+P ++ A + C CG T P A F P Sbjct: 95 ESEDIRDLRHEHHGNLVAVRGIIRKATDVRPKVIEAAFECQRCGTLTRIPQTAGDFQEP- 153 Query: 752 ACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRST 859 DC+ + G L T S+F + LR + + Sbjct: 154 ----HDCQGCERQGPFRLNTDQSQFIDAQKLRVQES 185 >UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=9; Magnoliophyta|Rep: Uncharacterized protein At5g44635.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 831 Score = 59.7 bits (138), Expect = 1e-07 Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 1/159 (0%) Frame = +2 Query: 404 FKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVP 583 F + + K D Y+ L R EM +P + V F +L +K Sbjct: 63 FNDALQKAIADEYLRFEPYLRNACKRFVIEM-NPSFISDDTPNKDINVSFYNLPFTKR-- 119 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +RE+ IGKLV+V G+VTR ++V+P L+ T+ C CG+ + ++T P C + Sbjct: 120 LRELTTAEIGKLVSVTGVVTRTSEVRPELLYGTFKCLDCGSVIKNVEQQFKYTQPTICVS 179 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLRYRST-RPSPGG 877 C LN+ L Q S+F ++ +R + T + P G Sbjct: 180 PTC-LNRARWALLRQE--SKFADWQRVRMQETSKEIPAG 215 >UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lamblia ATCC 50803|Rep: GLP_29_20689_22803 - Giardia lamblia ATCC 50803 Length = 704 Score = 59.7 bits (138), Expect = 1e-07 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = +2 Query: 482 IPGEMRDPRNRYPPELIRRF--EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTD 655 +P E R P L R F E+ ++ +P+R V A IG LV GIVT + Sbjct: 82 LPEEERGQYTNQPYRLSRWFSVEIVPENDMLEHPLPLRSVSASMIGHLVVFSGIVTFISQ 141 Query: 656 VKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGS 820 V P +AT++C CG+ Y V Q++ P C ++ C+ KT L T+ S Sbjct: 142 VVPECEIATFTCEVCGSSQYVVVPHDQYSIPQRCDSEVCQQLKTYEAPVLNTKRS 196 >UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: MCM family protein - Halorubrum lacusprofundi ATCC 49239 Length = 700 Score = 58.4 bits (135), Expect = 2e-07 Identities = 46/160 (28%), Positives = 76/160 (47%), Gaps = 11/160 (6%) Frame = +2 Query: 311 NEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPG 490 N+DLTE Q R Y + + P+ + + D D+Y R + E + P Sbjct: 6 NQDLTERFIQFYRNYYREEIGGLAQRYPNEQRSLYIEYD--DLYQFDRDLAEDFRTK-PE 62 Query: 491 EMRDPRNRYPPELIRRFEV---------YFKDLSTSKSVPIREVKA--EHIGKLVTVRGI 637 +MR+ Y E +R +++ + + + +S+ IR ++ +HIGKLV+++GI Sbjct: 63 QMRE----YAEEALRLYDLPADVSLGRAHVRIENLPESIDIRGIRVHDDHIGKLVSIKGI 118 Query: 638 VTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 V + TDV+P + A + C CG TY P F P C Sbjct: 119 VRKATDVRPKVTEAAFECQRCGTITYIPQSDGGFQEPHEC 158 >UniRef50_P53091 Cluster: DNA replication licensing factor MCM6; n=7; Saccharomycetales|Rep: DNA replication licensing factor MCM6 - Saccharomyces cerevisiae (Baker's yeast) Length = 1017 Score = 57.6 bits (133), Expect = 4e-07 Identities = 35/110 (31%), Positives = 62/110 (56%) Frame = +2 Query: 518 PPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSA 697 P + R F++ F +L T IR++++E IG L+++ G VTR ++V+P L A+++C Sbjct: 256 PEQTERVFQISFFNLPTVHR--IRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDM 313 Query: 698 CGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 C A ++ ++T P C C N+ L++ TR SRF ++ +R Sbjct: 314 CRAIVDNVEQSFKYTEPTFCPNPSCE-NRAFWTLNV-TR-SRFLDWQKVR 360 >UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 15 SCAF14542, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 996 Score = 57.2 bits (132), Expect = 5e-07 Identities = 37/112 (33%), Positives = 55/112 (49%) Frame = +2 Query: 527 LIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGA 706 L + F V +DL T IRE+ + IG LV + G V R V P LV T+ C C A Sbjct: 103 LNKEFYVALEDLPTRHK--IRELSSMRIGTLVKISGQVVRTHPVHPELVSGTFQCLDCQA 160 Query: 707 ETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRSTR 862 + +++PP C C N++ + HL T S+F F+ +R + T+ Sbjct: 161 LIRDVPQQFKYSPPTICRNPVCN-NRS--RFHLDTHKSKFIDFQKVRIQETQ 209 >UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7 homolog), putative; n=2; Theileria|Rep: DNA replication licensing factor (MCM7 homolog), putative - Theileria annulata Length = 827 Score = 56.4 bits (130), Expect = 9e-07 Identities = 53/244 (21%), Positives = 105/244 (43%), Gaps = 14/244 (5%) Frame = +2 Query: 158 ADKESFKNFFVDFC-----QTDDEGKKYF---KYAEQLTKVAHREQIAFEVDLDDLHEM- 310 A +S FF +F Q +D K F KY QL + + +V +DD+ + Sbjct: 17 AHTKSLSTFFEEFTSPLNLQDEDGDYKPFGDKKYKNQLQMIKNDSSKVLKVYMDDVRQYF 76 Query: 311 -----NEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARN 475 ++D E + NT RY ++ + EM+ E + KD + Y + + + + Sbjct: 77 LKENHDKDFYEGLMMNTYRYLELLY-IASEMV-----LEKLTKD--ENYPKFGLYYDPID 128 Query: 476 HRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTD 655 M+ +N+ P L +++ + + + ++ V A+ +G LV + V + + Sbjct: 129 ELRVSRMK--QNKLPINLRSNYDILLVNGNDDYIMKMKYVNADFVGCLVLIEVDVFKVAN 186 Query: 656 VKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKF 835 + P L++ATY C C +Y+ + + P C + L + S+F+K+ Sbjct: 187 ISPKLLIATYECDICHNHSYKTIEGNNYMPLMDC-VNCVSTRNVKSSLKFHPKLSKFEKY 245 Query: 836 RSLR 847 + +R Sbjct: 246 QEIR 249 >UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1; Haloquadratum walsbyi DSM 16790|Rep: ATP-dependent DNA helicase - Haloquadratum walsbyi (strain DSM 16790) Length = 2216 Score = 55.6 bits (128), Expect = 2e-06 Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 7/155 (4%) Frame = +2 Query: 314 EDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGE 493 +DLT+ Q R+Y + + P K + D D+Y + L R P + Sbjct: 9 QDLTDRFIQFYRKYYRDDIGTLAQQFPHEKRSLYI--DYHDLYA-FDVELAEDYRREPDQ 65 Query: 494 MRDPRNR----YP-PELIRRFEVYFKDLSTSKSVPIREVKA--EHIGKLVTVRGIVTRCT 652 +R+ Y P ++ + + S +V IR ++ +HIG L+ V+GIV + T Sbjct: 66 LREYAEEALRLYDLPADVKLGRAHVRMRSLPDTVDIRNIRVHDDHIGHLIAVQGIVRKAT 125 Query: 653 DVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 DV+P + A + C CG TY P F P C Sbjct: 126 DVRPKITEAAFECQRCGTMTYIPQSDSGFQEPHEC 160 >UniRef50_P49731 Cluster: DNA replication licensing factor mcm6; n=4; Dikarya|Rep: DNA replication licensing factor mcm6 - Schizosaccharomyces pombe (Fission yeast) Length = 892 Score = 55.6 bits (128), Expect = 2e-06 Identities = 28/88 (31%), Positives = 49/88 (55%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 IR+++ + IG+L T+ G VTR ++V+P L T+ C C +A ++T P C Sbjct: 198 IRDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFICEECHTVVSNVEQAFRYTEPTQCPN 257 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 + C NK + +L++ S FQ ++ +R Sbjct: 258 ELC-ANKRSWRLNISQ--SSFQDWQKVR 282 >UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium discoideum|Rep: MCM family protein - Dictyostelium discoideum AX4 Length = 867 Score = 54.8 bits (126), Expect = 3e-06 Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = +2 Query: 563 STSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFT 742 + S V IRE+++ IG L ++ G VTR ++V+P LV+ ++ C C + + ++T Sbjct: 164 NVSTFVHIRELRSSRIGSLCSISGTVTRTSEVRPELVIGSFICKDCNTSSLPIAQQFKYT 223 Query: 743 PPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRSTRPS-PGG 877 P C C N+ +++L+ S F ++ +R + PGG Sbjct: 224 EPTKCLNPLCS-NQRRWKINLEE--STFTDWQKVRVQENNSEIPGG 266 >UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1; Natronomonas pharaonis DSM 2160|Rep: ATP-dependent DNA helicase - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 1037 Score = 54.4 bits (125), Expect = 4e-06 Identities = 25/58 (43%), Positives = 32/58 (55%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 IR+++A H G LV V GIV + TDV+P + A + C CG T P A F P C Sbjct: 99 IRDIRARHRGNLVEVTGIVRKATDVRPKITEAAFECQRCGTLTRIPQTAGDFHDPHEC 156 >UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta thermophila PT|Rep: MCM family protein - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 689 Score = 54.4 bits (125), Expect = 4e-06 Identities = 27/91 (29%), Positives = 45/91 (49%) Frame = +2 Query: 587 REVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTAD 766 R+++++HIGKL+ + G V T+V+P +V A Y C CG Y +F P C + Sbjct: 95 RDLRSDHIGKLIAIEGQVRTATEVRPKIVRAAYECQRCGHVFYVDQSGTKFIEPYECPNE 154 Query: 767 DCRLNKTAGQLHLQTRGSRFQKFRSLRYRST 859 C G L + S+F + +R + + Sbjct: 155 AC---DRRGPFRLLPKRSQFVDAQKVRVQES 182 >UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lamblia ATCC 50803|Rep: GLP_680_44640_47504 - Giardia lamblia ATCC 50803 Length = 954 Score = 54.0 bits (124), Expect = 5e-06 Identities = 27/92 (29%), Positives = 47/92 (51%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 + E+ + HIG+LV + G VTR +DV+P L++ T+ C++CG + +FT P +C Sbjct: 139 LSELTSSHIGQLVELVGTVTRTSDVQPELILGTFRCASCGEVIPNVAQDYKFTEPASCPR 198 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLRYRST 859 R + L T F + +R + + Sbjct: 199 CSARSSVGGTTFELLTDQCTFADTQRVRLQES 230 >UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6, putative; n=7; Plasmodium|Rep: DNA replication licensing factor MCM6, putative - Plasmodium vivax Length = 944 Score = 53.6 bits (123), Expect = 6e-06 Identities = 21/63 (33%), Positives = 38/63 (60%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +R ++ E +G++++VRG VTR +DV+P L +A + C+ CG + ++T P C + Sbjct: 221 LRSLRCEMLGEMISVRGQVTRTSDVRPELTLAAFKCNECGNIINGVKQQFRYTQPSKCPS 280 Query: 764 DDC 772 C Sbjct: 281 SSC 283 >UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase, minichromosome maintenance protein; n=2; Pyrococcus|Rep: MCM inteins containing helicase, minichromosome maintenance protein - Pyrococcus abyssi Length = 1112 Score = 53.6 bits (123), Expect = 6e-06 Identities = 21/46 (45%), Positives = 32/46 (69%) Frame = +2 Query: 572 KSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE 709 K++ ++E+ AEHI KL+ V G+VTR T++KP + A + C CG E Sbjct: 100 KTLMVKEIGAEHINKLIQVEGVVTRVTEIKPFVSSAVFVCKDCGHE 145 >UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21; n=1; Halobacterium salinarum|Rep: MCM / cell division control protein 21 - Halobacterium salinarium (Halobacterium halobium) Length = 831 Score = 53.2 bits (122), Expect = 8e-06 Identities = 30/98 (30%), Positives = 47/98 (47%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 IR ++AEH+ +V+++G+V + TDV P + A + C CG +T P F P C Sbjct: 51 IRAIRAEHLNTMVSIQGMVRKATDVMPKIQRAVFVCQRCGTDTEVPQGDAGFQEPYQC-- 108 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLRYRSTRPSPGG 877 + C + G L S F + LR + + GG Sbjct: 109 ESC---ERQGPFKLDPDRSEFVDSQKLRIQESPEGLGG 143 >UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia bovis|Rep: MCM2/3/5 family protein - Babesia bovis Length = 918 Score = 52.8 bits (121), Expect = 1e-05 Identities = 20/63 (31%), Positives = 40/63 (63%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +++++ +G+L+T+ G VTR +DV+P L+ T+ C ACG+ + ++T P C++ Sbjct: 193 LKDLRCHMLGELLTISGQVTRTSDVRPELIRGTFKCKACGSFIRDIRQNFRYTVPNKCSS 252 Query: 764 DDC 772 + C Sbjct: 253 NSC 255 >UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1; Pyrococcus furiosus|Rep: Cell division control protein 21 - Pyrococcus furiosus Length = 1049 Score = 52.4 bits (120), Expect = 1e-05 Identities = 21/60 (35%), Positives = 38/60 (63%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQP 721 +++ + + +++ ++++ AEHI KL+ V GIVTR ++KP + VA + C CG E P Sbjct: 90 KIHARFYNLPETLMVKDIGAEHINKLIQVEGIVTRVGEIKPFVSVAVFVCKDCGHEMIVP 149 >UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Rep: Mcm protein - Methanosarcina acetivorans Length = 702 Score = 52.4 bits (120), Expect = 1e-05 Identities = 21/78 (26%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQP 721 + + + ++ VPI E++++H+GKL+++ G+V + T+V+P + A + C C T+ Sbjct: 84 DAHVRIMNVPTRVPIGELRSKHLGKLISIEGMVRKATEVRPRITKAAFQCLRCEHITFVD 143 Query: 722 VRALQFTPP-PACTADDC 772 + +F P C + C Sbjct: 144 QPSFKFEEPFSGCENETC 161 >UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus tropicalis|Rep: MGC146393 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 675 Score = 51.6 bits (118), Expect = 3e-05 Identities = 22/65 (33%), Positives = 36/65 (55%) Frame = +2 Query: 581 PIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACT 760 P++ ++A GK V +RG V R +++KPL V +SC+ CG P+ ++ P C Sbjct: 197 PLKNLRASLYGKYVALRGTVVRVSNIKPLCVKMAFSCNMCGDIQSFPLPDGKYAVPTKCP 256 Query: 761 ADDCR 775 +CR Sbjct: 257 VPECR 261 >UniRef50_UPI000049A27A Cluster: DNA replication licensing factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA replication licensing factor - Entamoeba histolytica HM-1:IMSS Length = 733 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/58 (39%), Positives = 33/58 (56%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 I+E+KA IGKL+ ++G V R + +KP LV + CS C A R ++T P C Sbjct: 119 IKELKASSIGKLICIKGTVIRASSIKPHLVSMVFCCSTCKANKEVTFRDGKYTEPKKC 176 >UniRef50_Q00Y49 Cluster: DNA replication licensing factor, MCM5 component; n=4; Ostreococcus|Rep: DNA replication licensing factor, MCM5 component - Ostreococcus tauri Length = 1327 Score = 51.2 bits (117), Expect = 3e-05 Identities = 22/69 (31%), Positives = 38/69 (55%) Frame = +2 Query: 593 VKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTADDC 772 VK+ +G++V++RG VTR +KP + ++C C + + ++ PP AC+ D C Sbjct: 169 VKSNVVGRVVSLRGTVTRAAPIKPAVTHMVFACQTCQERSRCTFKDGKYRPPLACSTDRC 228 Query: 773 RLNKTAGQL 799 R K +L Sbjct: 229 RGKKFVHEL 237 >UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7; n=8; Plasmodium|Rep: DNA replication licensing factor mcm7 - Plasmodium yoelii yoelii Length = 850 Score = 51.2 bits (117), Expect = 3e-05 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +2 Query: 491 EMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLL 670 E R + P L FE+ S +R V A+ IG L T V R T +KP + Sbjct: 201 EERMKEYKLPAYLRVNFEIILIPSSRDLIRKMRIVNADCIGSLSTFECEVIRATQLKPRI 260 Query: 671 VVATYSCSACGAETYQPVRALQFTP---PPACTADDCRLNKTAGQLHLQTRGSRFQKFRS 841 VATY C C Y+ V F P P CT ++ G L Q + S+F K++ Sbjct: 261 QVATYECDRCHVFAYKAVDGPFFMPLFDCPGCT----NVHGIRGSLKFQAKLSKFVKYQE 316 Query: 842 LR 847 ++ Sbjct: 317 IK 318 >UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermus marinus F1|Rep: MCM family protein - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 1047 Score = 51.2 bits (117), Expect = 3e-05 Identities = 34/87 (39%), Positives = 48/87 (55%) Frame = +2 Query: 461 LEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIV 640 +EA + I MR Y E + +F F++ SK + IRE+ +E+IGK V V GI+ Sbjct: 76 IEAASIAIKELMRRENPEYA-ESVDKFYPRFRN--PSKVLRIRELTSEYIGKFVAVEGIL 132 Query: 641 TRCTDVKPLLVVATYSCSACGAETYQP 721 TR T V+ LV A + + CGAE P Sbjct: 133 TRLTRVEARLVKAVFKHAECGAEFEWP 159 >UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY - Encephalitozoon cuniculi Length = 726 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/63 (36%), Positives = 35/63 (55%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 IRE+K+ +G+L++ G VTR T V+P LV T+ C CG+ + ++T P C Sbjct: 112 IRELKSNRLGQLLSFSGTVTRTTQVRPELVSGTFVCKICGSVIDNVFQEFKYTEPLTCPN 171 Query: 764 DDC 772 C Sbjct: 172 HLC 174 >UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM6; n=2; Ostreococcus|Rep: Mini-chromosome maintenance protein MCM6 - Ostreococcus tauri Length = 873 Score = 50.0 bits (114), Expect = 8e-05 Identities = 28/108 (25%), Positives = 55/108 (50%) Frame = +2 Query: 524 ELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 E R E + K ++ + +R ++A +IG+L + G VTR ++V+P L++ + C C Sbjct: 122 EKSREKEFWVKFVNLPRVERLRSLRANNIGQLSSFSGTVTRTSEVRPELLLGCFKCGECN 181 Query: 704 AETYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 + ++T P C + C N+T + L+ G +F ++ +R Sbjct: 182 TLVPNVEQQCRYTEPSICLLETCG-NRT--KWTLEREGCKFVDWQRVR 226 >UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 921 Score = 50.0 bits (114), Expect = 8e-05 Identities = 25/80 (31%), Positives = 41/80 (51%) Frame = +2 Query: 533 RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAET 712 R F++ F +L IRE+K + IG L+++ G VTR ++V+P L + + C C E Sbjct: 209 RHFQICFHNLPVV--CRIRELKTDKIGCLISLGGTVTRTSEVRPELYLGAFQCQECHTEV 266 Query: 713 YQPVRALQFTPPPACTADDC 772 + ++T P C C Sbjct: 267 DGVEQVFKYTEPSICPNPMC 286 >UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6 component; n=4; Saccharomycetaceae|Rep: DNA replication licensing factor, MCM6 component - Pichia stipitis (Yeast) Length = 949 Score = 50.0 bits (114), Expect = 8e-05 Identities = 24/75 (32%), Positives = 43/75 (57%) Frame = +2 Query: 533 RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAET 712 R F++ F +L T IR+++ IG L+++ G VTR ++V+P L A+++C C A Sbjct: 209 RVFQISFFNLPTINR--IRDIRTAKIGSLMSISGTVTRTSEVRPELFRASFTCDMCSAVI 266 Query: 713 YQPVRALQFTPPPAC 757 + ++T P +C Sbjct: 267 EGVEQVFKYTEPTSC 281 >UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 755 Score = 49.6 bits (113), Expect = 1e-04 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +2 Query: 581 PIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG--AETYQPVRALQFTPPPA 754 P+R++ I K+V VRG+VTRCT + P L +A + C CG E Q R PP Sbjct: 137 PMRDLNPSDIDKMVCVRGMVTRCTTIIPDLKLAYFKCLMCGFAPEHVQVDRGRVNEPPLK 196 Query: 755 CTADDCRLNKTAGQLHLQ 808 CT +C T +H Q Sbjct: 197 CT--ECGKPGTMTLIHNQ 212 >UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_99, whole genome shotgun sequence - Paramecium tetraurelia Length = 805 Score = 49.6 bits (113), Expect = 1e-04 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 2/114 (1%) Frame = +2 Query: 542 EVYFKDLST-SKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQ 718 ++YF +S + + IR+++A IGKL + G VTR +V+P L+ ++C C Sbjct: 102 KLYFLAVSNLAATEKIRDLRANKIGKLSSFIGTVTRTYEVRPELLSGQFTCQMCDRIIDN 161 Query: 719 PVRALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYR-STRPSPGG 877 + +FT P C C NK+ ++L S+F F+ +R + ++ P G Sbjct: 162 VEQQFKFTEPKKCPNTKCD-NKSRWTINLNK--SQFTDFQKVRVQEDSKDIPAG 212 >UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489; n=10; Methanococcales|Rep: Uncharacterized MCM-type protein MJ1489 - Methanococcus jannaschii Length = 682 Score = 49.6 bits (113), Expect = 1e-04 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Frame = +2 Query: 506 RNRYPPELI---RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVV 676 RN YP +I + FK K I +++++ +GKLV GI+ + ++P+L Sbjct: 87 RNEYPTNVIIAVKNLPKIFKTTRKGKIFTIEDIRSKTLGKLVEFEGIIVMASKIRPMLKK 146 Query: 677 ATYSCSACGAETYQPVRALQFTPPPACTADDCRLN 781 A Y C CG E + + L A LN Sbjct: 147 AYYICPKCGREVVREIDILNTDSEKAVCECGAELN 181 >UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM; n=4; Sulfolobaceae|Rep: Minichromosome maintenance protein MCM - Sulfolobus solfataricus Length = 686 Score = 37.9 bits (84), Expect(2) = 1e-04 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 482 IPGEMRDPRNRYPPELIRRFE-VYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDV 658 + G + D + P R E V+ + + + + +R++++ IGKL+T+ GI+ + T V Sbjct: 74 LEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPV 133 Query: 659 KPLLVVATY 685 K + ATY Sbjct: 134 KERIYKATY 142 Score = 31.1 bits (67), Expect(2) = 1e-04 Identities = 13/71 (18%), Positives = 34/71 (47%) Frame = +2 Query: 173 FKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRR 352 +++ F++F T KY E++ ++ + + ++ D+ NE+L + NT+ Sbjct: 10 YRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKI 69 Query: 353 YTNMVSDVVYE 385 ++ +Y+ Sbjct: 70 ILPILEGALYD 80 >UniRef50_Q979U9 Cluster: DNA replication initiator; n=4; Thermoplasmatales|Rep: DNA replication initiator - Thermoplasma volcanium Length = 699 Score = 49.2 bits (112), Expect = 1e-04 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 533 RRFEVYFKDLST-SKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE 709 R F + KDL + S IR++++ +IG L++V GIV + T+V P L A + CS C Sbjct: 88 RIFHLRIKDLEDRNTSYNIRDIRSANIGTLISVSGIVRKNTEVFPKLKNAAFECSNCHEL 147 Query: 710 TYQPVRALQFTPPPACTADDCRLNKTAGQLHLQTR 814 Y + T P C +C +K ++ + R Sbjct: 148 NYVEQNESRLTEPLYCA--NCGQSKVKDKISFKLR 180 >UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing factor; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative DNA replication licensing factor - Uncultured methanogenic archaeon RC-I Length = 862 Score = 49.2 bits (112), Expect = 1e-04 Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 1/101 (0%) Frame = +2 Query: 560 LSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRAL-Q 736 + + +RE+++ + KLV++ G V + TDV+P ++ A + C+ C Y P + Sbjct: 88 IKVPRKTQVRELRSSDVNKLVSLEGTVRKITDVRPRILEAAFECARCKNIIYIPQEGSGK 147 Query: 737 FTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYRST 859 F P C ++ + G L + SRF+ ++ ++ + + Sbjct: 148 FIEPSYCQCNE----EKKGIFRLMYKESRFEDYQRIKIQES 184 >UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole genome shotgun sequence; n=3; Magnoliophyta|Rep: Chromosome chr8 scaffold_29, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 741 Score = 48.8 bits (111), Expect = 2e-04 Identities = 22/67 (32%), Positives = 39/67 (58%) Frame = +2 Query: 578 VPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 + ++ +K+ +I KLV+VRG V + + VKPL+V T++C C + +F+PP Sbjct: 129 IALKNLKSAYIDKLVSVRGTVVKASTVKPLVVQMTFACVKCQTNILRIFHDGKFSPPSHS 188 Query: 758 TADDCRL 778 T D ++ Sbjct: 189 TIFDFKI 195 >UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_45, whole genome shotgun sequence - Paramecium tetraurelia Length = 803 Score = 48.0 bits (109), Expect = 3e-04 Identities = 36/143 (25%), Positives = 72/143 (50%), Gaps = 2/143 (1%) Frame = +2 Query: 281 EVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSL--DVYIEHR 454 E + L+++NE + + R+ ++ +Y+ L Y + + D++ V+ + Sbjct: 94 EYYMSQLNQLNET-DQFILNIDGRHLLEFNNHLYQQLIHYPAEIIPIFDTVVQKVFYDDF 152 Query: 455 IMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRG 634 + L+ARN + E R Y L+ ++ ++V +RE+ + I KL++V G Sbjct: 153 LSLKARNEQEREEFR----LYAQRLLIGI------INLERNVQVRELNPKDINKLISVTG 202 Query: 635 IVTRCTDVKPLLVVATYSCSACG 703 IV RC+++ P + AT+ C+ CG Sbjct: 203 IVIRCSELYPDMKQATFKCTKCG 225 >UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8 protein - Homo sapiens (Human) Length = 880 Score = 48.0 bits (109), Expect = 3e-04 Identities = 20/64 (31%), Positives = 35/64 (54%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 ++ V+A + GK + +RG V R +++KPL + C+ACG P+ +++ P C Sbjct: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266 Query: 764 DDCR 775 CR Sbjct: 267 PVCR 270 >UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing factor ATPase; n=2; Thermoprotei|Rep: Cdc46/Mcm DNA replication licensing factor ATPase - Cenarchaeum symbiosum Length = 697 Score = 48.0 bits (109), Expect = 3e-04 Identities = 27/88 (30%), Positives = 44/88 (50%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +RE+ A+ I K+ +V G+V R ++VKPL YSC T ++ + PP C+ Sbjct: 111 LREINADIINKMTSVSGMVVRASEVKPLAKELVYSCPEGHRTTVVLLKGMGVKPPTRCSD 170 Query: 764 DDCRLNKTAGQLHLQTRGSRFQKFRSLR 847 C + +L + S+F F+ LR Sbjct: 171 PKC----SHRELEPKPESSKFIDFQILR 194 >UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8; n=35; Deuterostomia|Rep: DNA replication licensing factor MCM8 - Homo sapiens (Human) Length = 840 Score = 48.0 bits (109), Expect = 3e-04 Identities = 20/64 (31%), Positives = 35/64 (54%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 ++ V+A + GK + +RG V R +++KPL + C+ACG P+ +++ P C Sbjct: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266 Query: 764 DDCR 775 CR Sbjct: 267 PVCR 270 >UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomonas vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas vaginalis G3 Length = 842 Score = 47.6 bits (108), Expect = 4e-04 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Frame = +2 Query: 506 RNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATY 685 R YP IR+ V L + IR+++ H+ LV +G+VTRC D+ P L+ + Sbjct: 229 RKMYPNLDIRKITVRITHLPIIDN--IRDLRQIHLDSLVRTKGVVTRCNDILPHLLQIKW 286 Query: 686 SCSACGAETYQP--VRALQFTPPPACTA 763 C CG + + P V + PP C A Sbjct: 287 RCEKCG-QVHGPFEVSDEKIYPPAFCAA 313 >UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep: NEQ282 - Nanoarchaeum equitans Length = 657 Score = 47.6 bits (108), Expect = 4e-04 Identities = 23/75 (30%), Positives = 45/75 (60%), Gaps = 2/75 (2%) Frame = +2 Query: 539 FEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQ 718 + + F D+ ++V IRE+++ H+ KLV + GI+ + + VKP+L A + S CG E + Sbjct: 72 YYIAFTDVQYYRNVKIRELRSHHLNKLVAIEGIIKQSSMVKPVLKRAVFRHS-CGYEVEK 130 Query: 719 PVRAL--QFTPPPAC 757 ++++ + + P C Sbjct: 131 EIKSISDKISKPKKC 145 >UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14; Ascomycota|Rep: DNA replication licensing factor - Aspergillus oryzae Length = 970 Score = 47.2 bits (107), Expect = 5e-04 Identities = 18/63 (28%), Positives = 34/63 (53%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +R+++ IGKL+++ G VTR ++++P L + T+ C C + ++T P C Sbjct: 239 LRQLRTSQIGKLLSISGTVTRTSEIRPELSLGTFICENCKTVCPDVEQTFKYTEPSECPN 298 Query: 764 DDC 772 C Sbjct: 299 QSC 301 >UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomonas vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas vaginalis G3 Length = 752 Score = 46.4 bits (105), Expect = 0.001 Identities = 29/87 (33%), Positives = 42/87 (48%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQP 721 EV + + ++ IRE+ I +LV+VRG++TR + V P L AT+ C AC P Sbjct: 146 EVQVRPYNLLETKSIRELHPTDIDRLVSVRGMITRSSPVIPDLSQATFRCRACKHVLSVP 205 Query: 722 VRALQFTPPPACTADDCRLNKTAGQLH 802 V + P C C+ N T H Sbjct: 206 VANGKVETPAQCPG--CKKNDTLEMEH 230 >UniRef50_Q5K7N5 Cluster: DNA unwinding-related protein, putative; n=2; Basidiomycota|Rep: DNA unwinding-related protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 989 Score = 46.4 bits (105), Expect = 0.001 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 7/149 (4%) Frame = +2 Query: 377 VYEMLPDYKFKEVVAKDSL--DVYIE--HRIMLEARNHRIPGEMRDPRNRYPPELIRRFE 544 +Y+ L +Y + + D + DV IE H + +A+ G + IR E Sbjct: 269 LYQQLVNYPQEVIPIMDQVLRDVMIELGHEELEKAQTKFAEGNLSQLELSLITNEIRDVE 328 Query: 545 --VY-FKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETY 715 VY + K+V +R++ KLVTV+G+V R T V P + A + C C Sbjct: 329 SRVYKVRPFGGEKTVNMRDLNPGDTDKLVTVKGLVIRATPVIPDMTTAFFRCLVCQHTVQ 388 Query: 716 QPVRALQFTPPPACTADDCRLNKTAGQLH 802 + + + P C D C T +H Sbjct: 389 ADIDRGRISEPERCPRDVCGSTGTMSLIH 417 >UniRef50_UPI000049880B Cluster: DNA replication licensing factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA replication licensing factor - Entamoeba histolytica HM-1:IMSS Length = 682 Score = 45.2 bits (102), Expect = 0.002 Identities = 19/66 (28%), Positives = 35/66 (53%) Frame = +2 Query: 575 SVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPA 754 SV +R++ + +G L + G +TR ++V+P L+ + C CG E+ + ++T P Sbjct: 129 SVTVRKLHSNLVGCLTSFYGTITRSSEVRPELIEGVFKCLDCGWESPPIPQQFKYTQPMR 188 Query: 755 CTADDC 772 C C Sbjct: 189 CLGSGC 194 >UniRef50_Q5V011 Cluster: MCM / cell division control protein 21; n=2; Halobacteriaceae|Rep: MCM / cell division control protein 21 - Haloarcula marismortui (Halobacterium marismortui) Length = 681 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/52 (38%), Positives = 28/52 (53%) Frame = +2 Query: 602 EHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPAC 757 E+IG+L+ +RG V + +DVKP L A + C CG +T P P C Sbjct: 106 ENIGQLLDIRGQVQKVSDVKPRLTEAVWECQRCGTQTEIPQHGDSLQEPHEC 157 >UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance protein; n=3; Methanobacteriaceae|Rep: Predicted minichromosome maintenance protein - Methanosphaera stadtmanae (strain DSM 3091) Length = 670 Score = 45.2 bits (102), Expect = 0.002 Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Frame = +2 Query: 377 VYEMLPDYKFKEVVAKDSLDVYIEHR--IMLEARNHRIPGEMRDPRNRYPPELIRRFEVY 550 V +M P+ K VV + L+++ +++E + + + N P + V Sbjct: 34 VLDMFPEEK-SVVVDYNELEMFDPDSADLLIEKPDETLEAATKSIVNIDPQRKNAKLNVR 92 Query: 551 FKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 FK++ + +P+R +++E IGK + V GIV + ++ P ++ A + C +C Sbjct: 93 FKNVRNN--IPLRFLRSEFIGKFIAVDGIVRKTDEIHPRIMSAVFECRSC 140 >UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=1; Ignicoccus hospitalis KIN4/I|Rep: replicative DNA helicase Mcm - Ignicoccus hospitalis KIN4/I Length = 689 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/80 (26%), Positives = 39/80 (48%) Frame = +2 Query: 533 RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAET 712 +++ + + + + V +R+++ ++GKLV GIVT+ T+VK + C ACG Sbjct: 90 KKYPMRVRFTNLPEKVRLRDLRERYVGKLVAFDGIVTKATNVKGKPKKLYFRCEACGTVF 149 Query: 713 YQPVRALQFTPPPACTADDC 772 R + P C +C Sbjct: 150 PVEQRGKYYQAPTVCPNPEC 169 >UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/3/5 family; n=1; Thermococcus kodakarensis KOD1|Rep: DNA replication licensing factor, MCM2/3/5 family - Pyrococcus kodakaraensis (Thermococcus kodakaraensis) Length = 810 Score = 44.8 bits (101), Expect = 0.003 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Frame = +2 Query: 524 ELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 E+ + V+F +L K P +V+AEH+GKLV ++G+VT ++V+ A + C CG Sbjct: 228 EVRGEWSVHFTNLR-DKLKP-EDVRAEHVGKLVEIKGLVTGVSNVRSFYRKAVFVCLDCG 285 Query: 704 ---AETYQPVRALQFTPPPACTA 763 A QP++ L P C A Sbjct: 286 ARMARLQQPLKPL--VRPKRCEA 306 >UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3 homolog; n=15; Magnoliophyta|Rep: DNA replication licensing factor MCM3 homolog - Arabidopsis thaliana (Mouse-ear cress) Length = 776 Score = 44.4 bits (100), Expect = 0.004 Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = +2 Query: 500 DPRNRYPPELIR-RFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVV 676 DP+ EL+ FE YF S+ V RE+ ++ IG +V V GIVT+C+ V+P +V Sbjct: 79 DPKYLKEGELVLVGFEGYF----VSRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVK 134 Query: 677 ATYSCSACGAETYQPVR 727 + + C + G T + R Sbjct: 135 SVHFCPSTGEFTNRDYR 151 >UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1; Tetrahymena thermophila SB210|Rep: MCM2/3/5 family protein - Tetrahymena thermophila SB210 Length = 797 Score = 44.0 bits (99), Expect = 0.005 Identities = 18/66 (27%), Positives = 36/66 (54%) Frame = +2 Query: 560 LSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQF 739 ++ +KS +R+++ + I +LV+++ IV R +D+ P + +A + CS C P+ Sbjct: 178 VNINKSTQLRDLRHKDINRLVSIKCIVIRVSDIYPEMKMAVFKCSRCSHSVIVPLERAHV 237 Query: 740 TPPPAC 757 P C Sbjct: 238 DEPNDC 243 >UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2; n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION LICENSING FACTOR MCM2 - Encephalitozoon cuniculi Length = 780 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/54 (38%), Positives = 30/54 (55%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTP 745 +R ++ H+GKLV V G+VTR + V PL + +SC C + P A F P Sbjct: 202 VRSLRNRHLGKLVRVSGVVTRRSGVFPLYSIVKFSCLKC-RSVFGPFVASSFKP 254 >UniRef50_Q5V814 Cluster: MCM / cell division control protein 21; n=1; Haloarcula marismortui|Rep: MCM / cell division control protein 21 - Haloarcula marismortui (Halobacterium marismortui) Length = 649 Score = 43.6 bits (98), Expect = 0.007 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +2 Query: 551 FKDLSTSKSVPIREVK-AEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVR 727 F++L S + E ++ G+L+ + G V + T V+P LV A + C CG T P Sbjct: 85 FENLPESHTTAPGEFSPSDRRGQLLALEGQVAKRTQVQPRLVEAAFECQRCGTLTRIPFE 144 Query: 728 ALQFTPPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSL 844 QF P C C +T G + SR++ ++ L Sbjct: 145 PGQFIEPFECVG--C---ETKGPFRINPDQSRYEDYQKL 178 >UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 17 SCAF14597, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 546 Score = 43.2 bits (97), Expect = 0.009 Identities = 20/65 (30%), Positives = 31/65 (47%) Frame = +2 Query: 581 PIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACT 760 P+R V+A G+LV V+G V R + ++PL + C C ++ +F P C Sbjct: 119 PLRMVRASVFGRLVCVKGTVVRVSSIRPLCTRMAFRCLGCSHTMSLLLQQGKFETPTKCG 178 Query: 761 ADDCR 775 CR Sbjct: 179 LPGCR 183 >UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured haloarchaeon|Rep: MCM family protein - uncultured haloarchaeon Length = 647 Score = 42.3 bits (95), Expect = 0.016 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE--TYQPVRALQFTPPPAC 757 IR ++A+ I LV + GI+++ T+VKP V + C G E +QP + T P C Sbjct: 130 IRNLRAKDINTLVGIDGIISKVTEVKPKFTVVVFQCEHDGHEVSVFQPDESFTSTTCPDC 189 Query: 758 TAD 766 ++ Sbjct: 190 GSE 192 >UniRef50_Q5JEJ0 Cluster: DNA replication licensing factor, MCM2/3/5 family; n=1; Thermococcus kodakarensis KOD1|Rep: DNA replication licensing factor, MCM2/3/5 family - Pyrococcus kodakaraensis (Thermococcus kodakaraensis) Length = 914 Score = 41.9 bits (94), Expect = 0.021 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 7/89 (7%) Frame = +2 Query: 536 RFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVT------RCTDVKPLLVVATYSCSA 697 R ++ + ++ K++ R V++EHIG+LV RG+V+ + VK + A + C Sbjct: 317 RPRIHVRFVNLPKTISPRAVRSEHIGRLVQARGVVSAIAEGEKSNGVKGFIEKAVFVCPK 376 Query: 698 CGAETYQPVRALQ-FTPPPACTADDCRLN 781 CG E + + F P C A RL+ Sbjct: 377 CGYEVSLLQKPYENFVVPKECPACGARLS 405 >UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2; Desulfurococcales|Rep: Minichromosome maintenance protein - Aeropyrum pernix Length = 697 Score = 41.5 bits (93), Expect = 0.027 Identities = 19/46 (41%), Positives = 28/46 (60%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQP 721 IR++ ++H+GKLV + GIVTR +V A + CGAE + P Sbjct: 112 IRDIGSDHVGKLVQINGIVTRMHPRATRMVRARFRHDRCGAEFWWP 157 Score = 37.9 bits (84), Expect = 0.33 Identities = 21/75 (28%), Positives = 40/75 (53%) Frame = +2 Query: 167 ESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNT 346 E FK F +F +EGK KY E + ++ + E+ + EV+ DL+ + L+E + + Sbjct: 16 ERFKTFLENF--RTEEGK--LKYVEAIRRMINYEETSLEVEFKDLYRYDPLLSEILLEKP 71 Query: 347 RRYTNMVSDVVYEML 391 R + S+ + E++ Sbjct: 72 REFLKEASEALKEIV 86 >UniRef50_Q4SLL7 Cluster: Chromosome 15 SCAF14556, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15 SCAF14556, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 934 Score = 41.1 bits (92), Expect = 0.036 Identities = 19/79 (24%), Positives = 37/79 (46%) Frame = +2 Query: 521 PELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 P+ I +++ + + K+ +R + E I +L+T+ G+V R + + P + A + C C Sbjct: 274 PDSILEYQIQVRPYNALKTKNMRSLNPEDIDQLITINGMVIRTSQLIPEMQEAFFQCQVC 333 Query: 701 GAETYQPVRALQFTPPPAC 757 T V + P C Sbjct: 334 AFTTRVEVDRGRIAEPAVC 352 >UniRef50_P30666 Cluster: DNA replication licensing factor mcm3; n=10; Fungi/Metazoa group|Rep: DNA replication licensing factor mcm3 - Schizosaccharomyces pombe (Fission yeast) Length = 879 Score = 41.1 bits (92), Expect = 0.036 Identities = 18/53 (33%), Positives = 32/53 (60%) Frame = +2 Query: 539 FEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSA 697 F V F+ V R ++A H+ K++++ GIVTRC+ V+P ++ + + C A Sbjct: 102 FYVGFRGSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEA 154 >UniRef50_UPI0000D56719 Cluster: PREDICTED: similar to minichromosome maintenance protein 8 isoform 1; n=1; Tribolium castaneum|Rep: PREDICTED: similar to minichromosome maintenance protein 8 isoform 1 - Tribolium castaneum Length = 769 Score = 40.7 bits (91), Expect = 0.047 Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC-GAETYQPVRALQFTPPPACT 760 I++++ + G+L++++G V + +VK + +SC+ C G + + + FT P C Sbjct: 156 IKDIRVNNYGRLISLKGTVIKAANVKIMYQYMAFSCATCTGIQVVKQPDNI-FTVPNKCL 214 Query: 761 ADDCRLNKTAGQLH 802 + C+ LH Sbjct: 215 TEGCKARSNFQALH 228 >UniRef50_Q4QJG9 Cluster: DNA replication licensing factor, putative; n=3; Leishmania|Rep: DNA replication licensing factor, putative - Leishmania major Length = 993 Score = 40.7 bits (91), Expect = 0.047 Identities = 19/67 (28%), Positives = 31/67 (46%) Frame = +2 Query: 575 SVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPA 754 + P + A +G+++T+RG V R + + V +Y C CG Q + T P Sbjct: 220 ATPFDHLGAAQLGRVLTIRGTVVRMSPARISCVCMSYRCGHCGVVKKQAAQDGVLTYPGP 279 Query: 755 CTADDCR 775 C + CR Sbjct: 280 CASARCR 286 >UniRef50_Q389T6 Cluster: Minichromosome maintenance (MCM) complex subunit, putative; n=3; Trypanosoma|Rep: Minichromosome maintenance (MCM) complex subunit, putative - Trypanosoma brucei Length = 711 Score = 39.9 bits (89), Expect = 0.083 Identities = 23/67 (34%), Positives = 30/67 (44%) Frame = +2 Query: 575 SVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPA 754 + P + A +GKLVTVRG V R + + V TY C+ C A P P Sbjct: 133 ATPFDTLGASLLGKLVTVRGTVVRMSPPRVTCVEMTYRCNLCAAVVKAPTEDGVLVYPGR 192 Query: 755 CTADDCR 775 C+ CR Sbjct: 193 CSG-RCR 198 >UniRef50_P33991 Cluster: DNA replication licensing factor MCM4; n=51; Bilateria|Rep: DNA replication licensing factor MCM4 - Homo sapiens (Human) Length = 863 Score = 39.9 bits (89), Expect = 0.083 Identities = 19/83 (22%), Positives = 39/83 (46%) Frame = +2 Query: 509 NRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYS 688 +RYP ++ ++ + + K+ +R + E I +L+T+ G+V R + + P + A + Sbjct: 247 DRYPDSILEH-QIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQ 305 Query: 689 CSACGAETYQPVRALQFTPPPAC 757 C C T + + P C Sbjct: 306 CQVCAHTTRVEMDRGRIAEPSVC 328 >UniRef50_P30665 Cluster: Cell division control protein 54; n=18; Eukaryota|Rep: Cell division control protein 54 - Saccharomyces cerevisiae (Baker's yeast) Length = 933 Score = 39.5 bits (88), Expect = 0.11 Identities = 20/73 (27%), Positives = 32/73 (43%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFTPPPACTA 763 +RE+ I KL+ ++G+V R T V P + VA + C+ C + P C Sbjct: 314 MRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCER 373 Query: 764 DDCRLNKTAGQLH 802 DC + +H Sbjct: 374 IDCNEPNSMSLIH 386 >UniRef50_Q22D74 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 2107 Score = 39.1 bits (87), Expect = 0.14 Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 1/109 (0%) Frame = +2 Query: 236 AEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLP-DYKFKE 412 A+QL + + + E + LH++++ L E +Q +Y N VSDV Y + + + +E Sbjct: 1882 ADQLQRSSRHQSDQEEYERRSLHQLDQ-LEEEDQQRDNQYLNQVSDVQYTLQEMESRIQE 1940 Query: 413 VVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKD 559 ++A+D + +H+ +LE + GE + + P+L R + + D Sbjct: 1941 LMARDE-EAQRQHQQILEDEQNYDHGEYNNNYSD-QPQLSLRIRLQYAD 1987 >UniRef50_P49736 Cluster: DNA replication licensing factor MCM2; n=45; Fungi/Metazoa group|Rep: DNA replication licensing factor MCM2 - Homo sapiens (Human) Length = 904 Score = 39.1 bits (87), Expect = 0.14 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 +R ++ H+ +L+ G+VT CT V P L + Y+C+ C Sbjct: 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC 332 >UniRef50_Q9LPD9 Cluster: T12C22.19 protein; n=18; Eukaryota|Rep: T12C22.19 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 936 Score = 38.7 bits (86), Expect = 0.19 Identities = 16/55 (29%), Positives = 30/55 (54%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGA 706 ++Y + + + IR ++ H+ ++ + G+VTR + V P L Y C+ CGA Sbjct: 306 KIYVRVTNLPVNDQIRNIRQIHLNTMIRIGGVVTRRSGVFPQLQQVKYDCNKCGA 360 >UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 like AAA+ ATpase; n=2; Cryptosporidium|Rep: DNA replication licensing factor MCM4 like AAA+ ATpase - Cryptosporidium parvum Iowa II Length = 896 Score = 38.7 bits (86), Expect = 0.19 Identities = 16/38 (42%), Positives = 26/38 (68%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSA 697 +REV I +LV++RGIV RC+D+ P + A + C++ Sbjct: 230 MREVNPSDIEQLVSIRGIVIRCSDIIPEMQKAVFRCTS 267 >UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 231 Score = 38.7 bits (86), Expect = 0.19 Identities = 17/57 (29%), Positives = 34/57 (59%) Frame = +2 Query: 533 RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 +++ + FK S SV R + + ++ K+V++ GIVTR + V+P ++ + + A G Sbjct: 109 QQYYLSFKGAFGSHSVTARSIDSSYLSKMVSIEGIVTRASLVRPKVIRSVHYAEATG 165 >UniRef50_Q019K0 Cluster: DNA replication licensing factor, MCM5 component; n=3; Ostreococcus|Rep: DNA replication licensing factor, MCM5 component - Ostreococcus tauri Length = 2370 Score = 38.3 bits (85), Expect = 0.25 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 3/61 (4%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFT---PPPA 754 I V+ H+ KL V G+ R K L + C CG + PV + + PPPA Sbjct: 1727 IGSVRTRHVNKLWCVEGVAVRVGSAKSLEAENVFECVKCGHQFLIPVNVEEGSGGEPPPA 1786 Query: 755 C 757 C Sbjct: 1787 C 1787 >UniRef50_Q5KDY4 Cluster: DNA replication licensing factor cdc19 (Cell division control protein 19), putative; n=9; Dikarya|Rep: DNA replication licensing factor cdc19 (Cell division control protein 19), putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 932 Score = 38.3 bits (85), Expect = 0.25 Identities = 17/55 (30%), Positives = 30/55 (54%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGA 706 E++ + S+ +R+++ ++ LV V G+VTR + V P L + C CGA Sbjct: 309 EIHVRITELPTSLSLRDLRQSNLNCLVRVSGVVTRRSGVFPQLKYVKFDCQKCGA 363 >UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF15020, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 965 Score = 37.9 bits (84), Expect = 0.33 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 IR ++ H+ +L+ G+V+ CT V P L + Y+C+ C Sbjct: 303 IRSLRQLHLNQLIRTSGVVSSCTGVLPQLGMVKYNCNKC 341 >UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena thermophila SB210|Rep: MCM2/3/5 family protein - Tetrahymena thermophila SB210 Length = 797 Score = 37.9 bits (84), Expect = 0.33 Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Frame = +2 Query: 533 RRFEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAET 712 +R +V + + +SV +R++KA I K + V+G+V + + V+ ++ T+ C C + Sbjct: 153 KRKKVIVRLYNYDQSVQLRDIKANIINKYLQVKGVVLKTSPVQVMINEMTFQCLDC--KQ 210 Query: 713 YQPVRALQ--FTPPPACTADDCRLNK 784 Q ++ L ++ P C C+ K Sbjct: 211 NQVIKFLYGIYSQPTKCLNTKCKGTK 236 >UniRef50_A5K611 Cluster: DNA replication licensing factor, putative; n=1; Plasmodium vivax|Rep: DNA replication licensing factor, putative - Plasmodium vivax Length = 1310 Score = 37.5 bits (83), Expect = 0.44 Identities = 15/39 (38%), Positives = 24/39 (61%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 ++E++++HIGK V+ GI+TR + K L Y C C Sbjct: 337 LQEIRSKHIGKFVSTEGIITRVGEKKILEECKKYRCMKC 375 >UniRef50_Q8SSE5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION LICENSING FACTOR OF THE MCM FAMILY - Encephalitozoon cuniculi Length = 708 Score = 37.5 bits (83), Expect = 0.44 Identities = 17/55 (30%), Positives = 28/55 (50%) Frame = +2 Query: 545 VYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE 709 + + + + IR + I K+V + G+V R + V P +V A + CS CG E Sbjct: 130 IRIRPFGIGRPLSIRNIDPNDIDKIVQISGMVIRSSSVIPEIVRAFFRCSRCGHE 184 >UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2 component; n=8; Eukaryota|Rep: DNA replication licensing factor, MCM2 component - Pichia stipitis (Yeast) Length = 859 Score = 37.5 bits (83), Expect = 0.44 Identities = 16/54 (29%), Positives = 29/54 (53%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 E++ + + K +R+++ + +L+ V G+VTR T V P L + C CG Sbjct: 293 EIHVRIVGFPKHTNLRDLRENDLNQLIKVGGVVTRRTGVFPQLKYVKFDCLKCG 346 >UniRef50_P29469 Cluster: DNA replication licensing factor MCM2; n=17; Ascomycota|Rep: DNA replication licensing factor MCM2 - Saccharomyces cerevisiae (Baker's yeast) Length = 868 Score = 37.5 bits (83), Expect = 0.44 Identities = 16/41 (39%), Positives = 25/41 (60%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGA 706 +RE++ ++ LV V G+VTR T V P L ++C CG+ Sbjct: 306 LRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGS 346 >UniRef50_Q5HCB0 Cluster: Putative uncharacterized protein Erum0660; n=3; Ehrlichia ruminantium|Rep: Putative uncharacterized protein Erum0660 - Ehrlichia ruminantium (strain Welgevonden) Length = 3715 Score = 37.1 bits (82), Expect = 0.58 Identities = 22/70 (31%), Positives = 37/70 (52%) Frame = +3 Query: 183 FSWIFVKLMMKEKSILNMLNNLLKLHTENR*HLKLTWMIYMR*MKI*LRQSNKIPEDTLI 362 F WI + K I+N+++ + + E H+KL MI ++ +RQS K+P + Sbjct: 1119 FVWILKNI--KPSEIINVIDENIAEYRETNDHMKLYDMI-----EVSIRQSYKVPNLPSM 1171 Query: 363 WCQTWFMKCC 392 + T F+KCC Sbjct: 1172 FTDTQFIKCC 1181 >UniRef50_A7S8B1 Cluster: Predicted protein; n=2; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 191 Score = 37.1 bits (82), Expect = 0.58 Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Frame = +2 Query: 209 DEGKKYFKYA---EQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVV 379 D+ ++Y KY E+L REQ +F+ ++DL ++ EAV++++ +T DV Sbjct: 45 DQEQRYLKYMSNLEELQNEEKREQESFKSQIEDLKTRCQEKQEAVEKSSADFTKFKFDVA 104 Query: 380 YEMLPDYKFKEVVAKD 427 + + K + KD Sbjct: 105 KQAINSRSGKPIPPKD 120 >UniRef50_UPI00006CFD9E Cluster: conserved hypothetical protein; n=1; Tetrahymena thermophila SB210|Rep: conserved hypothetical protein - Tetrahymena thermophila SB210 Length = 2254 Score = 36.7 bits (81), Expect = 0.77 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Frame = +2 Query: 203 TDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRY--TNMVSDV 376 TD + K YF EQ++K+ H+ Q + + ++ N +L E VK Y T M++D+ Sbjct: 963 TDSDIKDYFNKFEQISKITHQNQKEIQ-KIKEVIFQNNNLIELVKLPVNLYLTTRMLNDL 1021 Query: 377 VYEMLPDYKFKEV-VAKDSLDV 439 ++ D FK++ A D +D+ Sbjct: 1022 --DLKDDKIFKDLKQASDQVDI 1041 >UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 850 Score = 36.7 bits (81), Expect = 0.77 Identities = 16/54 (29%), Positives = 27/54 (50%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 E++ + +R+++ H+ LV V G+VTR + V P L + C CG Sbjct: 298 EIHVRIFDLPVHYTLRQLRQSHLNCLVRVSGVVTRRSGVFPQLKYVKFDCGKCG 351 >UniRef50_P24279 Cluster: DNA replication licensing factor MCM3; n=6; Saccharomycetales|Rep: DNA replication licensing factor MCM3 - Saccharomyces cerevisiae (Baker's yeast) Length = 971 Score = 36.7 bits (81), Expect = 0.77 Identities = 18/60 (30%), Positives = 36/60 (60%) Frame = +2 Query: 539 FEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQ 718 +++ FK + ++ R + A+H+ KLV+V GIVT+ + V+P L+ + + + G Y+ Sbjct: 153 WKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYR 212 >UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena thermophila SB210|Rep: MCM2/3/5 family protein - Tetrahymena thermophila SB210 Length = 730 Score = 36.3 bits (80), Expect = 1.0 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = +2 Query: 539 FEVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 F+V+ +ST +R++KA I KL+TV GI+T+ T + CS C Sbjct: 114 FQVFL--ISTQDPKNLRDIKASSISKLITVSGIITQATRPYIRSKILYVECSKC 165 >UniRef50_Q98RT4 Cluster: Putative uncharacterized protein orf670; n=1; Guillardia theta|Rep: Putative uncharacterized protein orf670 - Guillardia theta (Cryptomonas phi) Length = 670 Score = 36.3 bits (80), Expect = 1.0 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 3/97 (3%) Frame = +2 Query: 572 KSVPIREVK---AEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQPVRALQFT 742 K +PI E K + GK + ++GIVT+ +++ + A + CS C Y + Sbjct: 126 KKMPIYEFKIISTKLFGKYLKIKGIVTKISEILFEIKSAKFECSFCDFFVYNKKDIIINL 185 Query: 743 PPPACTADDCRLNKTAGQLHLQTRGSRFQKFRSLRYR 853 C C+L K + S +KF+ ++ + Sbjct: 186 NDFFCPNTRCKLGKRLKSMKFNLHESFIEKFKIIKLK 222 >UniRef50_A1CSW6 Cluster: DNA replication licensing factor MCM4; n=13; Ascomycota|Rep: DNA replication licensing factor MCM4 - Aspergillus clavatus Length = 1023 Score = 36.3 bits (80), Expect = 1.0 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 3/97 (3%) Frame = +2 Query: 521 PELIRRFEVY-FKDL--STSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSC 691 P+L+ E FK L +V +R++ + KLV+++G+V R T + P + A + C Sbjct: 376 PDLVGEVETKTFKVLPFGLDATVNMRDLDPADMDKLVSIKGLVIRTTPIIPDMKEAFFRC 435 Query: 692 SACGAETYQPVRALQFTPPPACTADDCRLNKTAGQLH 802 C + + P C C+ + +H Sbjct: 436 QICNHGVQVDIDRGKIAEPTECPRPVCKERNSMQLIH 472 >UniRef50_Q8I1S4 Cluster: DNA replication licensing factor, putative; n=2; cellular organisms|Rep: DNA replication licensing factor, putative - Plasmodium falciparum (isolate 3D7) Length = 1465 Score = 35.9 bits (79), Expect = 1.4 Identities = 15/39 (38%), Positives = 23/39 (58%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 I+E++ +HIGK ++ GI+TR + K L Y C C Sbjct: 430 IQEIENKHIGKFISTEGIITRVGEKKILEESKKYRCMRC 468 >UniRef50_Q4Q8I2 Cluster: Minichromosome maintenance (MCM) complex subunit, putative; n=5; Trypanosomatidae|Rep: Minichromosome maintenance (MCM) complex subunit, putative - Leishmania major Length = 969 Score = 35.5 bits (78), Expect = 1.8 Identities = 15/40 (37%), Positives = 22/40 (55%) Frame = +2 Query: 581 PIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 PIR+ + H+ LV V G+V R + V P + Y C+ C Sbjct: 314 PIRDFRQVHMNVLVRVEGVVIRRSPVYPQMDAVKYDCARC 353 >UniRef50_A0BNH6 Cluster: Chromosome undetermined scaffold_118, whole genome shotgun sequence; n=2; Oligohymenophorea|Rep: Chromosome undetermined scaffold_118, whole genome shotgun sequence - Paramecium tetraurelia Length = 985 Score = 35.5 bits (78), Expect = 1.8 Identities = 16/40 (40%), Positives = 24/40 (60%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 IR+++ +H+ K + V G+VTR + V L TY C CG Sbjct: 374 IRDLRYKHLDKFIRVIGVVTRRSAVYSQLKEITYVCVKCG 413 >UniRef50_UPI0000499A20 Cluster: hypothetical protein 53.t00045; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 53.t00045 - Entamoeba histolytica HM-1:IMSS Length = 511 Score = 35.1 bits (77), Expect = 2.4 Identities = 16/75 (21%), Positives = 38/75 (50%) Frame = +2 Query: 206 DDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYE 385 +D+ +K ++ + ++E+I ++ + EM + E K+N + NM Y Sbjct: 262 NDKQEKIESVLNEIKTICYKERIVMNKEISSIEEMEISIEEQNKENEQMVENMKGLEDYF 321 Query: 386 MLPDYKFKEVVAKDS 430 + +FK+++A++S Sbjct: 322 VQQTNEFKKIIAEES 336 >UniRef50_A3DIH5 Cluster: Radical SAM; n=1; Clostridium thermocellum ATCC 27405|Rep: Radical SAM - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 341 Score = 35.1 bits (77), Expect = 2.4 Identities = 21/95 (22%), Positives = 43/95 (45%) Frame = +2 Query: 245 LTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAK 424 ++K ++E E+D D+ + N ++K NT+ Y + + + KF + Sbjct: 149 VSKERYKETCGVEIDFDE-YVKNLSYLYSIKGNTQIYIKAIDATLKSKEEEEKFFNIFGN 207 Query: 425 DSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPEL 529 +YIEH I+++ + + + +N Y EL Sbjct: 208 ICDKIYIEHLIVMQQQMGELKKIVDGTKNFYNEEL 242 >UniRef50_A5AY09 Cluster: Putative uncharacterized protein; n=6; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 1018 Score = 35.1 bits (77), Expect = 2.4 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +2 Query: 59 LVVGAGDTFVISI*RQQLFV*HISKIMAMRDYTADKESFKNFFVDFC-QTDDEGKKYFKY 235 +V+G D +IS R Q + +S++ ++ K F F + + +G+K + Sbjct: 413 MVIGERDVIIISD-RHQGIIRSVSEVFGSENHAHCYRHIKENFXSFLTKLNTKGRKXKEN 471 Query: 236 AEQ-LTKVAH-REQIAFEVDLDDLHEMNEDLTEAVKQNTRRY 355 A Q L +A+ R +EV +D L N DL + V++N ++ Sbjct: 472 ALQMLDSIAYARLDCDYEVAMDTLRTFNHDLAKWVEENNPQH 513 >UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 915 Score = 35.1 bits (77), Expect = 2.4 Identities = 13/34 (38%), Positives = 25/34 (73%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATY 685 +R+++ IGKL++V G VTR ++++P L + T+ Sbjct: 242 LRQLRTSQIGKLLSVSGTVTRTSEIRPELSLGTF 275 >UniRef50_Q4T0H4 Cluster: Chromosome undetermined SCAF11052, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF11052, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 482 Score = 34.7 bits (76), Expect = 3.1 Identities = 17/56 (30%), Positives = 24/56 (42%) Frame = -2 Query: 726 RTGWYVSAPHALHEYVATTSSGFTSVHRVTIPRTVTSFPICSALTSLIGTLFDVDK 559 ++ W +PHA H YVA F + V I RT + + S FDV + Sbjct: 25 KSDWRSDSPHAAHNYVAILQDAFDLQYGVCILRTKEGLDVSHSSQSHFNAAFDVGR 80 >UniRef50_A0YYA0 Cluster: Putative uncharacterized protein; n=2; Lyngbya sp. PCC 8106|Rep: Putative uncharacterized protein - Lyngbya sp. PCC 8106 Length = 873 Score = 34.7 bits (76), Expect = 3.1 Identities = 21/110 (19%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Frame = +2 Query: 239 EQLTKVAHRE-QIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEV 415 E+L KV +E ++ + L+ H+ ED+ + + R++ + + E+ K+KE Sbjct: 214 EKLEKVLPQEAEVKPQKQLESKHQQAEDIQQQISDLKRQHQEQLQNREAEL--SVKYKEQ 271 Query: 416 VAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLS 565 + + ++ ++H+ LE ++ + ++ R EL+ + K ++ Sbjct: 272 IRQREAELSLQHQEQLEKSESQLKHQHQEQLKRRETELLAQINQLQKQIT 321 >UniRef50_Q5CNK7 Cluster: DNA replication licensing factor MCM2; n=2; Cryptosporidium|Rep: DNA replication licensing factor MCM2 - Cryptosporidium hominis Length = 970 Score = 34.7 bits (76), Expect = 3.1 Identities = 14/46 (30%), Positives = 25/46 (54%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAETYQP 721 +R+++ E + +L+ V GI+TR TD+ C CG ++ P Sbjct: 311 LRDLRVEWLNQLIRVSGIITRRTDILTKFKSLYMECVKCGCDSLGP 356 >UniRef50_Q54H83 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 726 Score = 34.7 bits (76), Expect = 3.1 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%) Frame = +2 Query: 155 TADKESFKNF--FVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTE 328 T+D S +NF F+D +D YFK + K+ +E + VD D ++ N+ T Sbjct: 28 TSDMVSIENFEFFLDHVYSDVLSSYYFKTLIEQEKILKKEDLNKIVDGDKDND-NKQATR 86 Query: 329 AVK-QNTRRYTNMVSDVVYEMLPDYKFKE---VVAKDSLDVY 442 + Q+ + +++ ++ + DYK K V+ DS +V+ Sbjct: 87 IINTQDKDKRIDIIKQIMNSKIRDYKTKVDNFVLESDSFEVF 128 >UniRef50_Q9A7Q4 Cluster: TonB-dependent receptor; n=4; Proteobacteria|Rep: TonB-dependent receptor - Caulobacter crescentus (Caulobacter vibrioides) Length = 809 Score = 34.3 bits (75), Expect = 4.1 Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Frame = -2 Query: 750 GGGVNCSARTGWYVSAPHALHEYVATTSSGFTSVHRVTIPRTVTSFPICSALTSLIGTL- 574 G + + TG+ AP ++ TTS+ F ++ V+ P V +FP SA+ ++G Sbjct: 501 GFAIRGAVSTGF--RAPALQQQFFTTTSTNFIIINGVSTPVEVGTFPATSAVAKVLGAKP 558 Query: 573 FDVDKSLKYTSNLLMSSGGY 514 + +KS ++ ++ G + Sbjct: 559 LEAEKSDNLSAGVVFQRGPF 578 >UniRef50_Q6JT33 Cluster: NADH-ubiquinone oxidoreductase chain 1; n=12; Araneae|Rep: NADH-ubiquinone oxidoreductase chain 1 - Heptathela hangzhouensis Length = 304 Score = 34.3 bits (75), Expect = 4.1 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = -2 Query: 537 LLMSSGGYLFLGSLISPGILWFLASNIILCSMY 439 LLM S YL + LI ILWF N+IL +M+ Sbjct: 151 LLMISNSYLLIDILIYQEILWFFLGNLILLTMW 183 >UniRef50_A7TQN0 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 443 Score = 34.3 bits (75), Expect = 4.1 Identities = 28/127 (22%), Positives = 55/127 (43%) Frame = +2 Query: 125 ISKIMAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLH 304 +S I + Y D S K F V + + EG K + L + RE+ + ++ Sbjct: 91 VSSIHEIDSYEEDTSSDKEFSV--VEKNIEGSKSKRNKRWLDRTVSREEPSKRQKYEE-E 147 Query: 305 EMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRI 484 E N+D ++A++ N+ TN+ S +M P+ + + LD ++ ++ + Sbjct: 148 EENDDFSKAIRMNSNTLTNVPSP-TSDMAPN-RIYNITFTSKLDGSVDKKLQARVLGKQQ 205 Query: 485 PGEMRDP 505 E+ P Sbjct: 206 FSEIMQP 212 >UniRef50_Q8ILG6 Cluster: Coatamer protein, beta subunit, putative; n=3; Plasmodium|Rep: Coatamer protein, beta subunit, putative - Plasmodium falciparum (isolate 3D7) Length = 1394 Score = 33.9 bits (74), Expect = 5.5 Identities = 15/50 (30%), Positives = 26/50 (52%) Frame = +3 Query: 99 EDSNYSYNIFLK*WQCVITLQIKNLSRTFSWIFVKLMMKEKSILNMLNNL 248 +++N+ NI K + ++ + R F W+ + M E I+N LNNL Sbjct: 645 KNNNFQNNILEKMIDSIFDIKKATILRIFFWVIGQYMFNEHMIINFLNNL 694 >UniRef50_Q5TN00 Cluster: ENSANGP00000028786; n=4; Culicidae|Rep: ENSANGP00000028786 - Anopheles gambiae str. PEST Length = 694 Score = 33.9 bits (74), Expect = 5.5 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = +2 Query: 230 KYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFK 409 K ++ K+A E + E + DL + E E +K+N R + + E+ P K + Sbjct: 432 KELDKCQKIAETEIMQCEFEKRDLRTLWEASNEVIKENENRLAELERRLKVELEPGAKSR 491 Query: 410 EVVAKDSLDVYIE-HRIMLEARNHRI 484 + + ++ D+ +E R+ E N+++ Sbjct: 492 DELETEARDLALECSRLKTEKYNYQL 517 >UniRef50_Q54LI2 Cluster: MCM family protein; n=2; Eukaryota|Rep: MCM family protein - Dictyostelium discoideum AX4 Length = 1008 Score = 33.9 bits (74), Expect = 5.5 Identities = 13/39 (33%), Positives = 23/39 (58%) Frame = +2 Query: 584 IREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 +R+++ ++ KL V G++TR ++V P L Y C C Sbjct: 401 LRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKC 439 >UniRef50_Q8PGT4 Cluster: Transcriptional regulator; n=6; Xanthomonas|Rep: Transcriptional regulator - Xanthomonas axonopodis pv. citri Length = 242 Score = 33.5 bits (73), Expect = 7.2 Identities = 17/49 (34%), Positives = 25/49 (51%) Frame = -2 Query: 804 RCSCPAVLLRRQSSAVQAGGGVNCSARTGWYVSAPHALHEYVATTSSGF 658 R +C + LR ++A G + R GW+VSAP Y T+ +GF Sbjct: 37 RFACTRITLREALQQLEAEGRIYRENRRGWFVSAPRV--RYDPTSIAGF 83 >UniRef50_Q67PC7 Cluster: DNA topoisomerase; n=1; Symbiobacterium thermophilum|Rep: DNA topoisomerase - Symbiobacterium thermophilum Length = 735 Score = 33.5 bits (73), Expect = 7.2 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 4/118 (3%) Frame = +2 Query: 362 MVSDVVYEMLPDYKFKEVVA--KDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIR 535 +V+D++ E PD E A + LD E R+ R G + + E + Sbjct: 541 LVTDILKEYFPDIIDVEFTAHLEGKLDEVEEGRVNWRELIRRFYGPFEETLKQ-AEEKVG 599 Query: 536 RFEVY--FKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 FE+ D+ K + VK GK + G C KP+L +C ACG Sbjct: 600 GFELEDEVSDVPCEKCGRLMVVKHGRFGKFLACPGF-PECKSTKPILEETGVTCPACG 656 >UniRef50_Q8GQC7 Cluster: NtrC; n=5; Leptospira|Rep: NtrC - Leptospira interrogans Length = 303 Score = 33.5 bits (73), Expect = 7.2 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 8/141 (5%) Frame = +2 Query: 236 AEQLTKVAHREQIAFEVDLDDLHEMNEDLT-------EAVKQNTRRYTNMVSDVVYEMLP 394 A Q+ + + E F +DL DL E ED+ E + +R +S+ +Y +L Sbjct: 134 AGQILESLYFEISNFRLDLPDLRERKEDIPLLIKHFLEILSDKYKRKEIRLSEKLYHILL 193 Query: 395 DYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSK 574 +Y F + + R +LE+ + D ++ PP++ VY + + Sbjct: 194 NYDFPGNIR--------QLRNLLESMISLFAVRILDVKH-LPPQMFETSYVYSEFIEVKT 244 Query: 575 SVPIREVKAEHIGK-LVTVRG 634 +P+R+ + E I K L+ V G Sbjct: 245 GIPLRDYEREIIKKNLILVNG 265 >UniRef50_Q6KD52 Cluster: Putative uncharacterized protein; n=4; Enterobacteriaceae|Rep: Putative uncharacterized protein - Escherichia coli Length = 186 Score = 33.5 bits (73), Expect = 7.2 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Frame = +2 Query: 233 YAEQLTKVAHR-EQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFK 409 Y + A R E L D H+ + +L EAV Q + M+ D++ +FK Sbjct: 81 YLDAFAGCAERGEMCGIYAMLSDSHQFSPELQEAVSQLAHQEIQMIKDIITSGQNSGEFK 140 Query: 410 EVVAKDSLDVYI 445 V+ D L V + Sbjct: 141 TVLLPDELAVIV 152 >UniRef50_A7HCY8 Cluster: Heavy metal efflux pump, CzcA family; n=9; Bacteria|Rep: Heavy metal efflux pump, CzcA family - Anaeromyxobacter sp. Fw109-5 Length = 1040 Score = 33.5 bits (73), Expect = 7.2 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Frame = +2 Query: 413 VVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIRE 592 V A+D LDV +EA R+ GE+R+ R+ P +R Y +D +VP+R Sbjct: 729 VAARDVLDV-------VEAVGTRVAGEVREGERRF-PLAVRLRAPYREDPEKLATVPVRT 780 Query: 593 VKAEHI--GKLVTVRGI 637 + + G+L T+R + Sbjct: 781 PSGDRVPLGRLATIREV 797 >UniRef50_A5VI77 Cluster: YidE/YbjL duplication; n=3; Lactobacillus reuteri|Rep: YidE/YbjL duplication - Lactobacillus reuteri F275 Length = 549 Score = 33.5 bits (73), Expect = 7.2 Identities = 20/52 (38%), Positives = 30/52 (57%) Frame = -2 Query: 645 RVTIPRTVTSFPICSALTSLIGTLFDVDKSLKYTSNLLMSSGGYLFLGSLIS 490 R +IP TVTSF LT +GT+ + + +TS + G LF+G++IS Sbjct: 421 RKSIPVTVTSFLQSFGLTLFVGTV-GLQSAQAFTSAIKSLGIGVLFIGAMIS 471 >UniRef50_Q9VDT2 Cluster: CG17186-PA; n=1; Drosophila melanogaster|Rep: CG17186-PA - Drosophila melanogaster (Fruit fly) Length = 381 Score = 33.5 bits (73), Expect = 7.2 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Frame = +2 Query: 212 EGKKYFKYAEQLTKVAHREQIAF--EVDLDDLHEMN--EDLTEAVKQNTRRYTNMVS-DV 376 E +Y + +L ++ HRE+ F E+D+D + E + ED+ + KQN N+V D Sbjct: 277 EPVEYLEAENELEEIDHREERNFVEELDMDVMEEPDVVEDIQDIDKQNGLEEINLVEIDE 336 Query: 377 VYEMLPDYKFKEVVAKDSLDVYIE 448 V ++ P ++ E + +VY E Sbjct: 337 VVQIDPGFEMIEYTTAEE-NVYEE 359 >UniRef50_Q7RI91 Cluster: Replication origin activator 2-related; n=8; Plasmodium|Rep: Replication origin activator 2-related - Plasmodium yoelii yoelii Length = 997 Score = 33.5 bits (73), Expect = 7.2 Identities = 14/33 (42%), Positives = 22/33 (66%) Frame = +2 Query: 587 REVKAEHIGKLVTVRGIVTRCTDVKPLLVVATY 685 R +++ I KLV V G+V +C+ V+P LV + Y Sbjct: 198 RGLQSSMINKLVAVEGVVNKCSTVQPKLVQSVY 230 >UniRef50_Q16ZI3 Cluster: DNA replication licensing factor MCM1; n=1; Aedes aegypti|Rep: DNA replication licensing factor MCM1 - Aedes aegypti (Yellowfever mosquito) Length = 1111 Score = 33.5 bits (73), Expect = 7.2 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Frame = +2 Query: 602 EHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACGAE---TYQPVRALQFTPPPAC-TADD 769 +++G+ V V+G V R T + L Y+CS C + Q ++ F PP AC A + Sbjct: 109 DNVGQFVQVKGSVIRMTQARFLEFKKEYTCSRCKNDFTLEAQYEKSYVFDPPRACPLAGE 168 Query: 770 CRLNKTAGQLHLQTRGSRFQKFRSLR 847 T Q Q + + ++ +R Sbjct: 169 TGCKGTPHQKSAQPQPDHCRDYQEIR 194 >UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomonas vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas vaginalis G3 Length = 698 Score = 33.5 bits (73), Expect = 7.2 Identities = 16/47 (34%), Positives = 23/47 (48%) Frame = +2 Query: 563 STSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSACG 703 + S+ P+RE+ + I KL+ V G+V T V CS CG Sbjct: 115 TNSEPTPLREIDSNLIKKLIVVPGLVISTTPVSSRATEIKAVCSGCG 161 >UniRef50_A0DPP4 Cluster: Chromosome undetermined scaffold_59, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_59, whole genome shotgun sequence - Paramecium tetraurelia Length = 2949 Score = 33.5 bits (73), Expect = 7.2 Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 3/107 (2%) Frame = +2 Query: 152 YTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFE-VDLDDLHEMNEDLTE 328 Y KE+F+N +DF Q + Y + QL KV + ++ E ++ + ++ + + Sbjct: 2051 YDGGKETFQNDCIDFIQHQIQSPVYDYFCSQL-KVMQKSELPMEYMESNKTCQIGKFI-- 2107 Query: 329 AVKQNTRRYTNMVSDVVYEMLPDYKF--KEVVAKDSLDVYIEHRIML 463 VK N ++ YE D++F K+V+ +++ +E+R+ L Sbjct: 2108 VVKMNKWIEQTYLTPSNYEPSNDFQFNWKQVLTYSTIEQSLENRLFL 2154 >UniRef50_UPI00004994EB Cluster: DNA replication licensing factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA replication licensing factor - Entamoeba histolytica HM-1:IMSS Length = 608 Score = 33.1 bits (72), Expect = 9.5 Identities = 17/53 (32%), Positives = 28/53 (52%) Frame = +2 Query: 542 EVYFKDLSTSKSVPIREVKAEHIGKLVTVRGIVTRCTDVKPLLVVATYSCSAC 700 EV + S+ IR + I +LV+VRG+VTR ++ P + + C+ C Sbjct: 81 EVEVRVFGLSQVKRIRGLSPSDIERLVSVRGMVTRVGNIIPSMKSGYFKCTEC 133 >UniRef50_Q91GJ2 Cluster: Putative uncharacterized protein; n=1; Epiphyas postvittana NPV|Rep: Putative uncharacterized protein - Epiphyas postvittana nucleopolyhedrovirus (EppoMNPV) Length = 881 Score = 33.1 bits (72), Expect = 9.5 Identities = 32/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%) Frame = +2 Query: 221 KYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPD- 397 K AE+ TK H E + L +N+++ E V +Y N + E L D Sbjct: 400 KALPVAEETTKNLHEELRGERATITKLQRINQEVQEKVNDLQTKYNNAQDE--NESLNDE 457 Query: 398 -YKFKEVVAK-DSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTS 571 K ++ K +SL +E L+ +N R+ + D N + E RR + L + Sbjct: 458 ISKLSPLIQKTESLKEEVER---LDKKNKRLKQNLADEHNNFLEEQQRRQNAQ-QSLQNT 513 Query: 572 KSVPIREV 595 + + I+ V Sbjct: 514 EDLQIQNV 521 >UniRef50_Q18YV3 Cluster: LPXTG-motif cell wall anchor domain precursor; n=1; Desulfitobacterium hafniense DCB-2|Rep: LPXTG-motif cell wall anchor domain precursor - Desulfitobacterium hafniense (strain DCB-2) Length = 2122 Score = 33.1 bits (72), Expect = 9.5 Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 5/66 (7%) Frame = -2 Query: 699 HALHEYVATTSSGFTSVHRVTI---PRTVT--SFPICSALTSLIGTLFDVDKSLKYTSNL 535 HA +Y A++SSG H VTI P TV + PI +T GT D+S+ +T+N+ Sbjct: 375 HAEFQYDASSSSGGAGDHTVTILGKPYTVNVPAVPIEYNVTK-TGTADLADQSITWTANI 433 Query: 534 LMSSGG 517 + GG Sbjct: 434 SATQGG 439 >UniRef50_Q54S44 Cluster: Putative uncharacterized protein; n=2; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 796 Score = 33.1 bits (72), Expect = 9.5 Identities = 22/101 (21%), Positives = 45/101 (44%) Frame = +2 Query: 317 DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEM 496 D++ +K+N ++ D +YE+L DY+ + D + + + N R ++ Sbjct: 2 DISGFLKENKESLKDLKEDDIYEILEDYEIDNI-----NDPKQKIKFFKKVENKRKRLKI 56 Query: 497 RDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKL 619 + +NR E + F + F++ + E K E + KL Sbjct: 57 EEEKNRMSEEEKKEFLIKFEEEKQKLKTEVEEEKKEFLIKL 97 >UniRef50_A7F6V0 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 966 Score = 33.1 bits (72), Expect = 9.5 Identities = 12/33 (36%), Positives = 24/33 (72%) Frame = +2 Query: 587 REVKAEHIGKLVTVRGIVTRCTDVKPLLVVATY 685 R + + H+ ++V++ GIVTRC+ V+P +V + + Sbjct: 117 RTLSSTHLNRMVSLEGIVTRCSLVRPKVVKSVH 149 >UniRef50_A3CTI4 Cluster: CRISPR-associated protein Cas1; n=1; Methanoculleus marisnigri JR1|Rep: CRISPR-associated protein Cas1 - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 392 Score = 33.1 bits (72), Expect = 9.5 Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 6/61 (9%) Frame = +2 Query: 272 IAFEVDLDDLHEMNEDLTEAV-KQNTRRYTNMVSDVVYEML-----PDYKFKEVVAKDSL 433 I + +LD LH+ E+L+ +V +N RR + + +D+ YE+L P+ F+ ++ L Sbjct: 210 IFYAGELDFLHQAREELSASVTMENLRRLSRLTTDMYYEILSRTLPPELGFRRRTSRPYL 269 Query: 434 D 436 D Sbjct: 270 D 270 >UniRef50_P20929 Cluster: Nebulin; n=63; Euteleostomi|Rep: Nebulin - Homo sapiens (Human) Length = 6669 Score = 33.1 bits (72), Expect = 9.5 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 26/153 (16%) Frame = +2 Query: 122 HISKIMAMRDYTADKESFKNFF---VDF--------CQTDDEGKKYFKYAEQLT------ 250 H++KI + R+Y D E +K F VD CQT Y Y Q T Sbjct: 2579 HVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAYKCQTLVSDVDYKNYLHQWTCLPDQS 2638 Query: 251 KVAHREQIAFEVDLDDLHEMNEDLTEAV---------KQNTRRYTNMVSDVVYEMLPDYK 403 V H Q A+++ D+L++ + + + + +R T ++SD VY PD + Sbjct: 2639 DVIHARQ-AYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPD-Q 2696 Query: 404 FKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRD 502 FK DS+ + + + NHR+ E D Sbjct: 2697 FKFSSLMDSIPMVLAKNNAI-TMNHRLYTEAWD 2728 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 764,103,234 Number of Sequences: 1657284 Number of extensions: 14897638 Number of successful extensions: 48083 Number of sequences better than 10.0: 145 Number of HSP's better than 10.0 without gapping: 45904 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 48041 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 78292544701 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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