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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fdpeP01_F_B15
         (926 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   190   3e-47
UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   179   8e-44
UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;...   161   3e-38
UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   153   6e-36
UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG222...   146   7e-34
UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   135   2e-30
UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...   128   2e-28
UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...   128   2e-28
UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...   124   4e-27
UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   122   1e-26
UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase ho...   119   9e-26
UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   118   2e-25
UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...   118   2e-25
UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   117   5e-25
UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1; ...   113   8e-24
UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   100   1e-19
UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin ...    89   1e-16
UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    83   1e-14
UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    77   1e-13
UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    68   4e-10
UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1; ...    64   5e-09
UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2; ...    64   6e-09
UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    63   1e-08
UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    61   5e-08
UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    60   1e-07
UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    58   2e-07
UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    58   4e-07
UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    56   2e-06
UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Re...    55   2e-06
UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=...    55   2e-06
UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5; Pr...    54   7e-06
UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    54   7e-06
UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6; Bradyrhizobiaceae...    53   1e-05
UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3; ...    53   1e-05
UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    52   3e-05
UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    52   3e-05
UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    51   5e-05
UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1; ...    51   5e-05
UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    50   8e-05
UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2; ...    49   1e-04
UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    49   2e-04
UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    48   3e-04
UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4; ...    48   3e-04
UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin ...    48   5e-04
UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    48   5e-04
UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    47   6e-04
UniRef50_Q74CF4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    46   0.002
UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: Ykv...    45   0.003
UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin s...    44   0.004
UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    44   0.007
UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.010
UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    43   0.010
UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.013
UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.013
UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    43   0.013
UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    41   0.052
UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    40   0.068
UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1; ...    39   0.16 
UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    39   0.16 
UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    38   0.36 
UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.36 
UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    38   0.48 
UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.48 
UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3; ...    38   0.48 
UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4; ...    37   0.64 
UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    37   0.84 
UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    37   0.84 
UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    37   0.84 
UniRef50_A7BS03 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    35   2.6  
UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1; ...    35   2.6  
UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase, p...    35   2.6  
UniRef50_A7AMF5 Cluster: Rab7; n=2; Babesia bovis|Rep: Rab7 - Ba...    35   3.4  
UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    35   3.4  
UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1; ...    34   4.5  
UniRef50_Q98S03 Cluster: Putative uncharacterized protein orf305...    34   4.5  
UniRef50_Q7RDH2 Cluster: CCAAT-box DNA binding protein subunit B...    34   4.5  
UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_030017...    34   5.9  
UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin ...    33   7.8  
UniRef50_Q97UC3 Cluster: Putative uncharacterized protein; n=1; ...    33   7.8  

>UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=35; Eumetazoa|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Homo sapiens (Human)
          Length = 145

 Score =  190 bits (464), Expect = 3e-47
 Identities = 82/126 (65%), Positives = 106/126 (84%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FS++HRL+S FLSDEEN K++GKCNNPNGHGHNY V+VTV G +DP TGMVMN+ DLKKY
Sbjct: 20  FSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKY 79

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           ++ AI++PLDHKNLD DVPYF  + STTENVA+Y+WD LQ+++    +L++VK+ ET+ N
Sbjct: 80  MEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVL-PVGVLYKVKVYETDNN 138

Query: 420 HVVYRG 437
            VVY+G
Sbjct: 139 IVVYKG 144


>UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=5; Endopterygota|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Drosophila melanogaster (Fruit fly)
          Length = 168

 Score =  179 bits (436), Expect = 8e-44
 Identities = 78/126 (61%), Positives = 102/126 (80%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FS+ HRLHSP LSD EN +V+GKCNN +GHGHNY V +TV+GP+D +TGMV+NIT+LK+ 
Sbjct: 15  FSACHRLHSPQLSDAENLEVFGKCNNFHGHGHNYTVEITVRGPIDRRTGMVLNITELKEA 74

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           I+T I++ LDHKNLD DV YF    STTEN+A+Y+WD ++  ++KP+LL+EVKI ET KN
Sbjct: 75  IETVIMKRLDHKNLDKDVEYFANTPSTTENLAVYIWDNIRLQLKKPELLYEVKIHETPKN 134

Query: 420 HVVYRG 437
            + YRG
Sbjct: 135 IISYRG 140


>UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 149

 Score =  161 bits (390), Expect = 3e-38
 Identities = 70/117 (59%), Positives = 90/117 (76%)
 Frame = +3

Query: 87  PFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 266
           P L+D+EN K+Y KCNNPNGHGHNY V +T++G V P TGMVMNI+DLK Y+K   L+ L
Sbjct: 32  PELTDDENIKLYDKCNNPNGHGHNYKVELTLRGKVYPVTGMVMNISDLKTYMKNGFLDLL 91

Query: 267 DHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRG 437
           DHKNLD DV YF++  ST EN+AI++WD++ + +  P LL EVK+ ET+KN  VYRG
Sbjct: 92  DHKNLDKDVNYFRSNVSTVENIAIFIWDRMAKCLPDPSLLFEVKVHETDKNIAVYRG 148


>UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Dictyostelium discoideum AX4|Rep:
           6-pyruvoyltetrahydropterin synthase - Dictyostelium
           discoideum AX4
          Length = 135

 Score =  153 bits (371), Expect = 6e-36
 Identities = 73/128 (57%), Positives = 97/128 (75%)
 Frame = +3

Query: 54  KLFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLK 233
           ++FSS+HRL+S  LS EENKK+YGKC N   HGHNYV+ V++KG V    GM MNIT+LK
Sbjct: 11  EVFSSSHRLYSDKLSLEENKKIYGKCIN--SHGHNYVLEVSIKGAVKEDIGMFMNITELK 68

Query: 234 KYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETE 413
           + +K  +++ LDHKNL+NDVP  K + +TTEN++I++WDQL   ++    L+EVKILETE
Sbjct: 69  EILKEKVMDKLDHKNLENDVPELKGIVTTTENLSIFIWDQLFPSLK--DFLYEVKILETE 126

Query: 414 KNHVVYRG 437
            N VVYRG
Sbjct: 127 NNFVVYRG 134


>UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG22232;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG22232 - Caenorhabditis
           briggsae
          Length = 137

 Score =  146 bits (354), Expect = 7e-34
 Identities = 67/129 (51%), Positives = 94/129 (72%)
 Frame = +3

Query: 51  VKLFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDL 230
           V++FS+AHRL+S  LS  ENK+ +GKCNN NGHGHNYV  V ++G VDP +GMV ++  L
Sbjct: 9   VEMFSAAHRLNSENLSVAENKETFGKCNNDNGHGHNYVWKVKLRGEVDPVSGMVYDLAKL 68

Query: 231 KKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILET 410
           KK +   +L+ +DH+NLD DV +FKT  ST+ENVAIY++ +L+ +M  P +L++  I ET
Sbjct: 69  KKEM-NLVLDTVDHRNLDKDVEFFKTTVSTSENVAIYMYQKLKSVMSNPSVLYKCTIEET 127

Query: 411 EKNHVVYRG 437
            KN   Y+G
Sbjct: 128 PKNVFTYKG 136


>UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Oikopleura dioica|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Oikopleura dioica
           (Tunicate)
          Length = 136

 Score =  135 bits (326), Expect = 2e-30
 Identities = 62/121 (51%), Positives = 85/121 (70%), Gaps = 1/121 (0%)
 Frame = +3

Query: 66  SAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIK 245
           + HRLHSP+L+DEEN+KVYGKCN+PNGHGHNY +   ++G +  +TGMVMN+ DL K   
Sbjct: 13  TGHRLHSPYLTDEENRKVYGKCNHPNGHGHNYTIQAVIEGEIIKETGMVMNLVDL-KVAM 71

Query: 246 TAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL-QRIMEKPQLLHEVKILETEKNH 422
             +L  LDH+N+D DV YFK + ST ENVA +++ QL Q +      L ++ + ET+KN 
Sbjct: 72  WKVLSQLDHRNVDKDVEYFKNVPSTAENVAQWIFIQLSQELPTGSYHLKKIILDETDKNR 131

Query: 423 V 425
           V
Sbjct: 132 V 132


>UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidetes|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Flavobacteria bacterium BBFL7
          Length = 136

 Score =  128 bits (310), Expect = 2e-28
 Identities = 57/126 (45%), Positives = 89/126 (70%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F++AHRLH    SD++N  ++GKCNNPN HGHNY + V V G VDP+TG ++++  LK  
Sbjct: 11  FNAAHRLHRSDWSDQKNAAIFGKCNNPNFHGHNYNLEVGVTGKVDPETGYLIDLKILKDV 70

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           IK+ + +  DHKNL+ +VP FKT+  T EN+A  ++++++  ++    + E+K+ ETE+N
Sbjct: 71  IKSEVEDAFDHKNLNVEVPEFKTLNPTAENIAYVIYNKIKAKLDSKYDI-EIKLYETERN 129

Query: 420 HVVYRG 437
            VVY+G
Sbjct: 130 FVVYKG 135


>UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=2;
           Bacteria|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           uncultured marine bacterium Ant39E11
          Length = 137

 Score =  128 bits (309), Expect = 2e-28
 Identities = 58/128 (45%), Positives = 89/128 (69%), Gaps = 1/128 (0%)
 Frame = +3

Query: 57  LFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKK 236
           +FS+AHRL +P  SDE+N+ V+G C N   HGHN+ ++VTVKG V+  TG VMN+ DLK 
Sbjct: 9   IFSAAHRLANPSWSDEKNQAVFGHCANEYSHGHNFQLIVTVKGEVNTDTGFVMNMVDLKA 68

Query: 237 YIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQ-RIMEKPQLLHEVKILETE 413
            + + I++ +DH+NL++DVP+ + +  +TEN+A+  W Q++  I +    LH ++I+ETE
Sbjct: 69  IMDSEIIQHVDHRNLNHDVPFMQGIMPSTENLAMIFWQQIEGPIAKHGAALHCIRIVETE 128

Query: 414 KNHVVYRG 437
            N V Y G
Sbjct: 129 NNMVEYYG 136


>UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Acidobacteria|Rep: 6-pyruvoyl tetrahydropterin synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 137

 Score =  124 bits (298), Expect = 4e-27
 Identities = 55/126 (43%), Positives = 84/126 (66%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FS++H  H+P  + EEN +V+GKCNN NGHGHNY + VTVKG VD  TG V+++  LK+ 
Sbjct: 11  FSASHHYHNPDFTAEENLRVFGKCNNSNGHGHNYTLEVTVKGTVDATTGFVVDLKQLKEI 70

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           +   +++ +DH+ L+++VP FK+   TTEN+AI +W +L+  +   + LH V++ E    
Sbjct: 71  MNREVVDAMDHRYLNHEVPEFKSQIPTTENIAIAIWKRLEGKLHVAK-LHRVRLYEMHDL 129

Query: 420 HVVYRG 437
            V Y G
Sbjct: 130 WVDYLG 135


>UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyltetrahydropterin synthase -
           Geobacillus kaustophilus
          Length = 134

 Score =  122 bits (294), Expect = 1e-26
 Identities = 57/126 (45%), Positives = 83/126 (65%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FSSAHRLHS  L++EEN++++GKCNN  GHGHNY + VTV G  DP TGMV+N+ +L + 
Sbjct: 7   FSSAHRLHSDQLTNEENQRLFGKCNNRYGHGHNYCLEVTVIGKPDPITGMVVNLAELDEI 66

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           +   +L   DHK+L+ D   FK +  T EN+ I +W+ L   +     L+++ + ET+KN
Sbjct: 67  VNREVLVKFDHKHLNLDTDEFKQINPTAENIVIVIWELLAPHLSS---LYKIGLWETQKN 123

Query: 420 HVVYRG 437
           +  Y G
Sbjct: 124 YFEYFG 129


>UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase
           homolog; n=35; Cyanobacteria|Rep:
           6-pyruvoyl-tetrahydropterin synthase homolog -
           Synechococcus sp. (strain CC9311)
          Length = 306

 Score =  119 bits (287), Expect = 9e-26
 Identities = 53/121 (43%), Positives = 81/121 (66%), Gaps = 1/121 (0%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F++AHRL  P LS EEN+ +YGKC  P+GHGHNY+V VTV+G +DP+TGMV ++  L++ 
Sbjct: 162 FAAAHRLARPELSQEENELIYGKCARPHGHGHNYLVDVTVRGSIDPRTGMVCDLAALQRL 221

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR-IMEKPQLLHEVKILETEK 416
           +   ++EP DH  L+ DV +F     T EN+A+++ D+L   +      LH+V++ E+  
Sbjct: 222 VSDLVVEPFDHTFLNKDVAHFADCVPTAENIALHIVDRLTTPVRAIGAQLHKVRLQESPN 281

Query: 417 N 419
           N
Sbjct: 282 N 282



 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 38/104 (36%), Positives = 61/104 (58%), Gaps = 5/104 (4%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FSS+HR   P LS ++N   +G C    GHGHNY ++V++ G +D   GMV+N++++K  
Sbjct: 24  FSSSHRYWLPELSADDNAARFGSCAMAPGHGHNYELIVSMAGGLD-ANGMVLNLSEVKHA 82

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMAS-----TTENVAIYVWDQL 356
           I++ + E LD + L+   P F   +S     TTE +   +W +L
Sbjct: 83  IRSEVTEQLDFRFLNEAWPEFDVSSSEGCLPTTEALVRIIWSRL 126


>UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=10; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 149

 Score =  118 bits (284), Expect = 2e-25
 Identities = 56/130 (43%), Positives = 88/130 (67%), Gaps = 4/130 (3%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F++AHRL +P LSDEEN+++YGKC+   GHGHNY++ +T+ G +D +TG + ++ +LKK 
Sbjct: 19  FNAAHRLFNPELSDEENQQLYGKCSGKYGHGHNYLLEITLSGIIDRKTGYLFDLKELKKI 78

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWD----QLQRIMEKPQLLHEVKILE 407
           ++  I+   DH++L+++V        TTE +A+ VW+    +L+ I ++   LHEV I E
Sbjct: 79  LEEEIVARFDHRHLNHEVNELAGHVPTTEILAVIVWEILDSRLKTITKQEVSLHEVIIHE 138

Query: 408 TEKNHVVYRG 437
           T KN V YRG
Sbjct: 139 TGKNSVTYRG 148


>UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Acidobacteria bacterium Ellin345|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Acidobacteria bacterium
           (strain Ellin345)
          Length = 135

 Score =  118 bits (284), Expect = 2e-25
 Identities = 56/120 (46%), Positives = 84/120 (70%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F ++HRLH+P LS+ EN++VYGKCNNP GHGHNY + VTV G V P TGMV N+ D+ + 
Sbjct: 11  FVASHRLHTPRLSEAENREVYGKCNNPFGHGHNYALEVTVGGQVAPDTGMVYNLADVDRV 70

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           ++  ILE  DH+NL N +  F+ +  TTEN+ + +++ L+R + +   L +V++ ET +N
Sbjct: 71  VRKHILERYDHQNL-NCLKEFQELVPTTENLCLAIFEILKRNLAEIH-LDKVRLEETSQN 128


>UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=13;
           Bacteroidetes|Rep: 6-pyruvoyltetrahydropterin synthase -
           Leeuwenhoekiella blandensis MED217
          Length = 137

 Score =  117 bits (281), Expect = 5e-25
 Identities = 53/126 (42%), Positives = 82/126 (65%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F++AHRL+     D +N +V+GKC+ PN HGHNY ++V V G +DP+TG V+++  LK  
Sbjct: 12  FNAAHRLYRADWDDAKNLEVFGKCSYPNYHGHNYELIVAVTGEIDPKTGFVIDLKVLKDL 71

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKN 419
           IK+ + EP DHKNL+ DV  F  +  T EN+ + ++D+L+  ++  +   EV + ET +N
Sbjct: 72  IKSEVEEPFDHKNLNLDVAEFSQLNPTAENICVVIYDRLKAKLD-AKFAIEVTLYETPRN 130

Query: 420 HVVYRG 437
            V Y G
Sbjct: 131 SVTYSG 136


>UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative
           uncharacterized protein - Solibacter usitatus (strain
           Ellin6076)
          Length = 141

 Score =  113 bits (271), Expect = 8e-24
 Identities = 53/125 (42%), Positives = 83/125 (66%), Gaps = 5/125 (4%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F+++HRLHS  LS EEN+ +YGKCNNP GHGHNYVV V+V+GPVD  TG  ++I  L + 
Sbjct: 7   FAASHRLHSDQLSAEENRSLYGKCNNPYGHGHNYVVEVSVRGPVDEATGRTVDIVLLDEL 66

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKP-----QLLHEVKIL 404
           ++  +++P DH+NL+ +V  F    +T+EN+   +  +L+R  ++        L +++I 
Sbjct: 67  VRREVVQPFDHRNLNAEVDAFTKAVATSENLGFEICRRLKRNWKEVFPGEWPKLEKIRIG 126

Query: 405 ETEKN 419
           ET +N
Sbjct: 127 ETARN 131


>UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Flexibacteraceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Microscilla marina ATCC
           23134
          Length = 158

 Score = 99.5 bits (237), Expect = 1e-19
 Identities = 49/129 (37%), Positives = 81/129 (62%), Gaps = 3/129 (2%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F+++H+L++P  S E+N+ ++G C N N HGHN+ ++VTVKG  D +TGMV++   L K 
Sbjct: 10  FNASHKLYNPNWSKEQNEALFGVCANQNWHGHNFELVVTVKGMPDLETGMVIDYKVLSKI 69

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM--EKPQ-LLHEVKILET 410
           ++  I+E + +KNL+ DV +      + E + I  W +L   +  E P+  LH +K++ET
Sbjct: 70  VRREIIEKVHYKNLNLDVDFLAGKMPSCEILIIEFWKRLAPAIQQESPRTTLHHLKLVET 129

Query: 411 EKNHVVYRG 437
           + N V Y G
Sbjct: 130 KNNSVEYMG 138


>UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Desulfotalea psychrophila|Rep: Related to
           6-pyruvoyl tetrahydropterin synthase - Desulfotalea
           psychrophila
          Length = 136

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 43/118 (36%), Positives = 77/118 (65%), Gaps = 1/118 (0%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           F +AH+L    L+D+EN++ +GKC+    HGH Y + +T+ G V P  GMV+N TDLK+ 
Sbjct: 12  FDAAHKLFLKDLTDQENREAFGKCSQL--HGHTYCLRITITGKVQP-NGMVLNFTDLKQI 68

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILET 410
           ++  I+   DH +L N++  ++ + +T EN+++Y++  L   ++K ++ L EV++ ET
Sbjct: 69  VEEKIIARYDHSHL-NELEEYRDLPTTAENMSLYIFKVLAACLKKQKVTLTEVQLYET 125


>UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Thermotoga
           maritima
          Length = 120

 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 47/106 (44%), Positives = 69/106 (65%), Gaps = 1/106 (0%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 302
           GKC     HGH Y ++V ++GP++ +  MVM+  +LKK ++  ++  LDH  L ND+  F
Sbjct: 20  GKCERL--HGHTYRLVVKIEGPLNEEE-MVMDFAELKKIVEELVISKLDHSYL-NDM--F 73

Query: 303 KTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVYRG 437
                TTE VAI++WDQL + MEK  + LHE+++ ETE + VVYRG
Sbjct: 74  DQ--PTTERVAIWIWDQLSKEMEKRGVRLHEIELWETETSGVVYRG 117


>UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Salmo salar|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Salmo salar (Atlantic salmon)
          Length = 103

 Score = 76.6 bits (180), Expect(2) = 1e-13
 Identities = 41/77 (53%), Positives = 55/77 (71%)
 Frame = +3

Query: 207 MVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLL 386
           +VMNIT++K++I+  I  PLDHKNLD DVPYF  +     NVA+Y+ D + + +    LL
Sbjct: 34  LVMNITNIKEHIEEVI--PLDHKNLDKDVPYFANV-----NVAVYIXDNMVKQL-PANLL 85

Query: 387 HEVKILETEKNHVVYRG 437
           +EVKI ET+KN VVYRG
Sbjct: 86  YEVKIHETDKNIVVYRG 102



 Score = 23.4 bits (48), Expect(2) = 1e-13
 Identities = 9/15 (60%), Positives = 12/15 (80%)
 Frame = +3

Query: 51 VKLFSSAHRLHSPFL 95
          V+ F ++HRLHSP L
Sbjct: 20 VQSFCASHRLHSPTL 34


>UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Gammaproteobacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Thiomicrospira crunogena
           (strain XCL-2)
          Length = 125

 Score = 67.7 bits (158), Expect = 4e-10
 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+ + V V G      GM+++  ++K++ K  I E LDH  L ND P+FK    T E
Sbjct: 30  HGHNWKIEVQVVGDKLNDIGMLVDFKEIKRHAKEVISE-LDHTFL-NDHPHFKEKNPTAE 87

Query: 327 NVAIYVWDQL-QRIMEKPQLLHEVKILETEKNHVVY 431
           N+A Y++ Q+ QRI      +H + + E ++N V+Y
Sbjct: 88  NIAEYIYKQIQQRIQSSTVKMHSLTVWENDRNCVIY 123


>UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 133

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 39/107 (36%), Positives = 63/107 (58%), Gaps = 6/107 (5%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDP-----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 287
           GKC     HGH+Y++ V+V+G + P       GMV+++  +K+ +   I+  +DH NL N
Sbjct: 22  GKCARL--HGHSYLLEVSVRGLIQPTRGQSDDGMVIDLEQIKQLVNEIIIARVDHYNL-N 78

Query: 288 DVPYFKTMASTTENVAIYVWDQL-QRIMEKPQLLHEVKILETEKNHV 425
           D   F ++ ST EN+A ++WDQL Q+  E   LL  +++ ET   +V
Sbjct: 79  D---FLSVPSTAENIAHWMWDQLEQQAPEFAALLWRIRLWETASGYV 122


>UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2;
           Acidobacteria|Rep: Putative uncharacterized protein -
           Acidobacteria bacterium (strain Ellin345)
          Length = 125

 Score = 63.7 bits (148), Expect = 6e-09
 Identities = 31/82 (37%), Positives = 51/82 (62%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 302
           GKC NP  HGHNY V VT++G      G++++  DLK  +K  +++ LDH+ + ND+P F
Sbjct: 21  GKCENP--HGHNYKVRVTLQGRELDHAGLLLDFKDLKVVMK-PVVDYLDHQMM-NDIPPF 76

Query: 303 KTMASTTENVAIYVWDQLQRIM 368
             +  + EN+A Y +D+  + +
Sbjct: 77  NEVNPSAENIARYFYDECNKFL 98


>UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 129

 Score = 62.9 bits (146), Expect = 1e-08
 Identities = 35/97 (36%), Positives = 55/97 (56%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHNY   V ++G VDP TGM+ +  D+K+ +   +L  +DH+ L NDV        T E
Sbjct: 37  HGHNYRFFVALEGEVDPATGMIADFGDVKRIVAEHVLARVDHRTL-NDV----LDNPTAE 91

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRG 437
           N+A ++W+ L+  +     L E+++ E   + V YRG
Sbjct: 92  NIARWMWEVLEPHLAG---LCEIRLYEIPDSCVTYRG 125


>UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=24; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Shigella flexneri
          Length = 121

 Score = 60.9 bits (141), Expect = 5e-08
 Identities = 35/97 (36%), Positives = 56/97 (57%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH+++V + + G VDP TG +++  +LK   K    E LDH  L ND+P  +    T+E
Sbjct: 31  HGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPT-YERLDHHYL-NDIPGLEN--PTSE 86

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRG 437
            +A ++WDQ++ ++    LL  V + ET     +YRG
Sbjct: 87  VLAKWIWDQVKPVV---PLLSAVMVKETCTAGCIYRG 120


>UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Clostridia|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           Thermoanaerobacter tengcongensis
          Length = 122

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 36/98 (36%), Positives = 59/98 (60%), Gaps = 1/98 (1%)
 Frame = +3

Query: 120 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 299
           +GKC     HGH Y + VTV+G  D + GMV++   LK+ +   I++ LDHK L N+V  
Sbjct: 19  HGKCEEL--HGHTYRLEVTVEGYPDEE-GMVLDFVKLKEIVNEKIIKKLDHKYL-NEVLG 74

Query: 300 FKTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILET 410
           F T   T EN+ +++W +L+  ++ P   L+++ + ET
Sbjct: 75  FNT---TCENILLWMWKELEGELKGPNYKLYKLTLWET 109


>UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 129

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 31/108 (28%), Positives = 57/108 (52%)
 Frame = +3

Query: 60  FSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKY 239
           FS+AH    P   + +N++ +G+C    GHGHNY++        D       +   +   
Sbjct: 9   FSAAHFYAQPQWDEHKNRETFGRCYTQYGHGHNYMLEAGFHCQNDSWKQQQQHYQSVLNN 68

Query: 240 IKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 383
           + TA+   LDH++L+  +P FKT   TTEN+ +Y  ++L+  ++  ++
Sbjct: 69  L-TAV---LDHEHLNFVIPEFKTNIPTTENICLYFLEKLKSQVKSEEI 112


>UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Pedobacter sp. BAL39|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Pedobacter sp.
           BAL39
          Length = 117

 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 31/97 (31%), Positives = 57/97 (58%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH Y + V + G  DP +G V +  DLK+ I+   ++ LDH+ L ND+P  +    T+E
Sbjct: 28  HGHTYQLTVYLSGTPDPHSGWVADFGDLKRGIQ-PFVDLLDHRLL-NDIPGLEN--PTSE 83

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRG 437
           N+++++W +++ +      L ++++ ET    V+Y G
Sbjct: 84  NLSVWLWQKIKPVF---PALAKIELSETPGTGVIYEG 117


>UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=2; Actinomycetales|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Mycobacterium ulcerans (strain Agy99)
          Length = 160

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 40/131 (30%), Positives = 64/131 (48%)
 Frame = +3

Query: 45  YAVKLFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNIT 224
           Y    F SAHRL         N     KC     HGH+Y     V+GPVDP+ G +++  
Sbjct: 8   YCEFTFESAHRL--------PNVPAGHKCGRL--HGHSYRARTYVEGPVDPRAGWIVDFG 57

Query: 225 DLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKIL 404
            +K   K  I   LDH  L N++   +    T+E +++++W +L  ++  P ++  V + 
Sbjct: 58  KIKDACKPVIAR-LDHYYL-NEIDGLEN--PTSEQLSMWIWRELATLL--PMMMSAVSVS 111

Query: 405 ETEKNHVVYRG 437
           ET  +  +YRG
Sbjct: 112 ETCSSGCMYRG 122


>UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Rep:
           Mll8751 protein - Rhizobium loti (Mesorhizobium loti)
          Length = 117

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 31/97 (31%), Positives = 56/97 (57%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH+Y V + ++GPVDP TG V++  D++  +   +L+ LDH+ L N++        T E
Sbjct: 28  HGHSYRVELRLEGPVDPDTGFVIDFFDVEA-VFGPLLQRLDHQYL-NEIEGLDN--PTAE 83

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRG 437
           N+A+++W+Q + ++ +   +  V + ET      Y G
Sbjct: 84  NIAVWIWNQTKPLLGQ---MCSVTVYETPLCWAEYEG 117


>UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=1;
           Granulibacter bethesdensis CGDNIH1|Rep: Queuosine
           biosynthesis protein queD - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 130

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 28/70 (40%), Positives = 47/70 (67%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH+Y V V ++G VDP +GM+M++  L++ +  A+ + LDH+ LD +VP      +T E
Sbjct: 39  HGHSYRVEVVLRGGVDPDSGMLMDLGLLQRKM-NAVRDALDHRLLD-EVP--GLAPATME 94

Query: 327 NVAIYVWDQL 356
           N+A+++W  L
Sbjct: 95  NIALFIWRHL 104


>UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5;
           Proteobacteria|Rep: Queuosine biosynthesis protein -
           Syntrophus aciditrophicus (strain SB)
          Length = 159

 Score = 53.6 bits (123), Expect = 7e-06
 Identities = 30/97 (30%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+ V VTV+     + G+ ++  ++K+ ++ A L  LDH NL N++P F  +  ++E
Sbjct: 63  HGHNWAVEVTVECEELNEIGIGIDFREVKQSVREA-LHRLDHVNL-NELPQFCDINPSSE 120

Query: 327 NVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVYR 434
           N+A +++++L R +   ++ +  V++ ET  +   YR
Sbjct: 121 NIARHLYNELSRKLNTEKIRVSRVRVSETPTSKASYR 157


>UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=3;
           cellular organisms|Rep: 6-pyruvoyltetrahydropterin
           synthase - Methanosarcina acetivorans
          Length = 123

 Score = 53.6 bits (123), Expect = 7e-06
 Identities = 35/116 (30%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
 Frame = +3

Query: 90  FLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLD 269
           F +  + K V  KC N   HGHN+ + V V G      G++M+  +LK+ + + I + LD
Sbjct: 10  FAAAHQLKMVAKKCENL--HGHNWKIEVCVAGEKLNDAGIMMDFGELKQNV-SEITKTLD 66

Query: 270 HKNLDNDVPYFK-TMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVY 431
           H N  N++ YF      ++EN+A+Y+ + L+ +++ P++ +  V   E+E     Y
Sbjct: 67  H-NFLNELDYFDDNNPPSSENIAVYIANSLKAMLKDPEIRVASVTAWESENACATY 121


>UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6;
           Bradyrhizobiaceae|Rep: Bll2482 protein - Bradyrhizobium
           japonicum
          Length = 121

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 30/73 (41%), Positives = 46/73 (63%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH++   VTV+G  DP+TGMV+++  L++ I+   L  LDHK L+      K    T E
Sbjct: 29  HGHSFRAEVTVRGTPDPETGMVVDLGLLQRAIEDVRL-TLDHKFLNKIEALGK---PTLE 84

Query: 327 NVAIYVWDQLQRI 365
           N++ +VW++LQ I
Sbjct: 85  NLSRFVWERLQHI 97


>UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3;
           Deltaproteobacteria|Rep: Putative uncharacterized
           protein - Syntrophobacter fumaroxidans (strain DSM 10017
           / MPOB)
          Length = 127

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 28/98 (28%), Positives = 59/98 (60%), Gaps = 1/98 (1%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 302
           GKC N   HGHN+ + + ++G    + G++++  ++K+  + A+L  +DH  L N++P+F
Sbjct: 25  GKCENL--HGHNWKIEIVLRGTELNEIGVLVDFGEVKQATR-ALLSEVDHHYL-NEIPFF 80

Query: 303 KTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETE 413
                ++EN+A Y++++L    +  +L L+ V   E++
Sbjct: 81  ADRNPSSENIARYLFERLAEKFDNDKLRLYRVSAWESD 118


>UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=18; Bacilli|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Bacillus
           anthracis
          Length = 163

 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 28/92 (30%), Positives = 51/92 (55%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 302
           GKC N   HGH Y V+  + G V+ + G+ ++  D+K+  K  I   LDH+ L+  +P  
Sbjct: 51  GKCKNL--HGHTYKVVFGISGYVN-EIGLAIDFGDIKEIWKNEIEIYLDHRYLNETLP-- 105

Query: 303 KTMASTTENVAIYVWDQLQRIMEKPQLLHEVK 398
             M +T EN+ +++++++   + K    +E K
Sbjct: 106 -AMNTTAENMVVWIYEKMAEALTKDNRANEYK 136


>UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Methanosarcina barkeri str. Fusaro|Rep:
           6-pyruvoyltetrahydropterin synthase - Methanosarcina
           barkeri (strain Fusaro / DSM 804)
          Length = 112

 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 32/99 (32%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
 Frame = +3

Query: 90  FLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLD 269
           F +  + K V  KC N   HGHN+ V V V G    + G++++  +LK+ + + I+  LD
Sbjct: 10  FAAAHQLKMVAKKCENL--HGHNWKVEVCVAGEKLNEAGVLVDFGELKQKV-SEIVTRLD 66

Query: 270 HKNLDNDVPYFK-TMASTTENVAIYVWDQLQRIMEKPQL 383
           H N  N++ YF  +   ++EN+A Y+   LQ +++ P++
Sbjct: 67  H-NFLNELEYFNDSNPPSSENIAQYIATSLQTMLKDPEI 104


>UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Parvibaculum lavamentivorans
           DS-1
          Length = 122

 Score = 50.8 bits (116), Expect = 5e-05
 Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
 Frame = +3

Query: 75  RLHSPFLSDEENKKVYGKCNNPNG--HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKT 248
           +++  FL D  +   Y +  +PN   HGH++ V+V +KG    +TG+V +  D+++ I  
Sbjct: 2   KIYKEFLFDAAHFLPYAEEGHPNRRMHGHSFRVVVWLKGKPAAETGIVRHFEDVEREI-M 60

Query: 249 AILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 356
           A+ E LDH +L N++   +    T E +A ++WD L
Sbjct: 61  AVREKLDH-HLLNEIEGLE--FPTLERIAAWIWDAL 93


>UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Putative
           uncharacterized protein - Victivallis vadensis ATCC
           BAA-548
          Length = 112

 Score = 50.8 bits (116), Expect = 5e-05
 Identities = 28/96 (29%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHNY + VTV+     + G+ ++   LK  +  A+L   DH NL +++  F+ +  T+E
Sbjct: 16  HGHNYKITVTVRSSELDEIGIALDFKKLKAEL-DALLAEYDHSNL-SELADFQAVNPTSE 73

Query: 327 NVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVY 431
           N+A  ++ ++   M    + +H V++ E++ + V Y
Sbjct: 74  NLARTIYRKISEKMNSGTIRVHRVRVGESDHSAVTY 109


>UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides fragilis
          Length = 110

 Score = 50.0 bits (114), Expect = 8e-05
 Identities = 32/95 (33%), Positives = 54/95 (56%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+++ V  +       GMV++ T +K+ +K    E LDH+NL+  +P+      T E
Sbjct: 28  HGHNWIITVYCRSERLNADGMVVDFTQIKQAVK----EKLDHRNLNEVLPF----NPTAE 79

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVY 431
           N+A +V  Q+      PQ  ++V++ E+E N V+Y
Sbjct: 80  NIARWVCKQI------PQ-CYKVEVQESEANTVIY 107


>UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2;
           Peptococcaceae|Rep: Putative uncharacterized protein -
           Desulfotomaculum reducens MI-1
          Length = 128

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 32/101 (31%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF--KTMAST 320
           HGH + V V V G    + GM+++  D+KK + T I+   DH  + ND+P F    +  T
Sbjct: 27  HGHTWTVEVKVFGKELNELGMLIDFKDIKKQLAT-IINEFDHSYI-NDLPGFGEDGVNPT 84

Query: 321 TENVAIYVWDQLQRIMEKPQL---LHEVKILETEKNHVVYR 434
            EN++ Y++  L + +   Q+   L EV + E+   +  YR
Sbjct: 85  AENLSYYIFQTLAQRISSIQMGVKLKEVSVWESPDAYATYR 125


>UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Dehalococcoides|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Dehalococcoides sp. (strain CBDB1)
          Length = 123

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 35/106 (33%), Positives = 60/106 (56%), Gaps = 2/106 (1%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVK-GPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 299
           GKC N   HGH Y V + VK G +D + GM  + + LK  +   +L+  DH  L ND+  
Sbjct: 21  GKCENL--HGHRYEVALKVKTGELD-ECGMGADFSLLKTRLNE-VLQSYDHTCL-NDLTP 75

Query: 300 FKTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVYR 434
           F  +  + EN+A  ++D+L+ ++ K  + L  V++ E+  + V+Y+
Sbjct: 76  FDNINPSAENIAKDIYDKLKTVINKKGVELWGVEVWESPDSSVLYQ 121


>UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides thetaiotaomicron
          Length = 124

 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 34/106 (32%), Positives = 55/106 (51%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+++ V  +       GMV++ T     IK  + E LDH+NL+  +P+      T E
Sbjct: 28  HGHNWIITVYCRSSRLNSEGMVVDFT----RIKEVVTEKLDHQNLNEVLPF----NPTAE 79

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRGGNTYSRKKP 464
           N+A +V  Q+      PQ  ++V++ E+E N V+Y      + K P
Sbjct: 80  NIARWVCRQI------PQ-CYKVEVQESEGNIVIYEKDAVANEKTP 118


>UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 124

 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 27/72 (37%), Positives = 47/72 (65%), Gaps = 2/72 (2%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD--NDVPYFKTMAST 320
           HGH+Y   VTV+G  DP TGM++++  L++ ++ A  + LDH+ LD  ND+       +T
Sbjct: 29  HGHSYRAEVTVRGRPDPATGMIVDLGLLERSMEDA-RDALDHRFLDEINDLG-----PAT 82

Query: 321 TENVAIYVWDQL 356
            EN++ ++W++L
Sbjct: 83  MENLSRWIWNRL 94


>UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Staphylococcus haemolyticus JCSC1435|Rep:
           Similar to 6-pyruvoyl tetrahydropterin synthase -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 143

 Score = 47.6 bits (108), Expect = 5e-04
 Identities = 26/95 (27%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPV-DPQTGMVMNITDLKKYIKTAILEP-LDHKNLDNDVPYFKTMAST 320
           H H+Y + V V  P+ D   G+  N  D    I   ++EP L+H+ ++  +P    M +T
Sbjct: 46  HNHSYRLYVDVLSPIGDYGLGLDFNEVDA---IYNKVIEPKLNHQLINETLP---DMNTT 99

Query: 321 TENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHV 425
            EN+A+++WD+ ++ +     ++ +++ ET+++ V
Sbjct: 100 AENIAMWIWDEFEQHLPGEHCMYALQLFETDRHGV 134


>UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosococcus oceani (strain
           ATCC 19707 / NCIMB 11848)
          Length = 99

 Score = 47.6 bits (108), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+ + V V      Q GMVM+  D+K+  +  +   LDH+ L ND+  F  +  T E
Sbjct: 2   HGHNWKLEVEVTAQALDQQGMVMDFKDIKESAR-ELCAQLDHRYL-NDISPFDLINPTAE 59

Query: 327 NVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVY 431
           N+A + +  L + +   +  +  + + ETE+  V Y
Sbjct: 60  NLAAFFYRGLSKQLNNERARVSAITLWETERACVRY 95


>UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 135

 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 28/95 (29%), Positives = 58/95 (61%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH++ +++T+ G +DP+ G V++  D++  +K  +L+ +DH+ L N+VP  +    T+E
Sbjct: 45  HGHSFKLILTLVGDLDPKIGWVIDYNDIQALMK-PLLDQIDHRVL-NEVPGLEN--PTSE 100

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVY 431
            +A +++D+ +  +  P L+ +V + ET      Y
Sbjct: 101 LLAKWLYDKARPFL--PTLV-KVTVAETPATECSY 132


>UniRef50_Q74CF4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase
           family protein; n=7; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase family protein - Geobacter
           sulfurreducens
          Length = 122

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 31/119 (26%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
 Frame = +3

Query: 78  LHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAIL 257
           +H+ F +        G C N   HGHN+ V V+V      + G+ ++   LK+     +L
Sbjct: 6   IHTSFAAAHCLINYQGDCENL--HGHNWRVEVSVTARELDKAGLGIDFKVLKQE-TNGLL 62

Query: 258 EPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHVVY 431
             LDHK L N++  FK ++ ++EN++ Y++ +L R +    + +  + + E++     Y
Sbjct: 63  RTLDHKYL-NELEPFKEISPSSENISRYLYHELSRRLNDGNVTVESITVWESDNAAATY 120


>UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 129

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 5/103 (4%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHNY V + V      + GM ++   ++   +  ++  +DH+ L N++P F  +  T E
Sbjct: 30  HGHNYKVEIEVACEQLDELGMGVDFRAVRAAARE-VVGVIDHRFL-NEIPPFTEVNPTAE 87

Query: 327 NVAIYVWDQLQRIM-----EKPQLLHEVKILETEKNHVVYRGG 440
           ++A Y+++ L R +     E+ QL   + + ETE++ V Y  G
Sbjct: 88  HIAAYIYEGLARRLAELAGERVQLA-AITVWETERDSVTYTEG 129


>UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Putative
           uncharacterized protein - Thermosinus carboxydivorans
           Nor1
          Length = 130

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVK---GPV---DPQTGMVMNITDLKKYIKTAILEPLDHKNLD 284
           GKC     HGH Y + VTV+   G V    P+ GMV++   L   IK  +++ LDHK L+
Sbjct: 25  GKCAQM--HGHTYRLEVTVERKDGGVATGGPEDGMVIDFGRLSALIKDRVVDKLDHKVLN 82

Query: 285 NDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILETEKNHV 425
           +  P+      T+EN+A +++ +L  I+    + +  V + ET  ++V
Sbjct: 83  DCFPF----RPTSENMARHIFIELSAILANEDVNVVRVVLWETPTSYV 126


>UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: YkvK
           protein - Bacillus subtilis
          Length = 149

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL--DHKNLDNDVPYFKTMAST 320
           HGH Y V +TV G     +G ++N + LKK +       L  DH++   D  Y      T
Sbjct: 44  HGHTYTVNITVAGDELDDSGFLVNFSVLKKLVHGNYDHTLLNDHEDFSQDDRY---SLPT 100

Query: 321 TENVAIYVWDQLQRIME----KPQLLHEVKILETEKNHVVYR 434
           TE VA  ++D +Q  ++    KP  + +V + ET  ++ VYR
Sbjct: 101 TEVVAKTIYDNVQAYLDTLENKPTCV-QVFVRETPTSYCVYR 141


>UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin
           synthase; n=4; Thermococcaceae|Rep: PtpS-like
           6-pyruvoyl-tetrahydropterin synthase - Pyrococcus abyssi
          Length = 115

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 28/93 (30%), Positives = 52/93 (55%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH + + V V+G +  + G +M+ T+L+K +   + E L+H+NL+     F     TTE
Sbjct: 27  HGHTFFLEVAVEGEI--KRGYIMDFTELRKIVDDIVKE-LNHRNLNK---IFDN--PTTE 78

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHV 425
           NVA+++ ++++  +     L  V + E + N V
Sbjct: 79  NVALWIAEKVEEKLPHKVKLKRVVLWEGKDNGV 111


>UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=1;
           Pelotomaculum thermopropionicum SI|Rep:
           6-pyruvoyl-tetrahydropterin synthase - Pelotomaculum
           thermopropionicum SI
          Length = 129

 Score = 43.6 bits (98), Expect = 0.007
 Identities = 26/96 (27%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
 Frame = +3

Query: 78  LHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAIL 257
           + + F +    K   G C+    HGH ++V   ++G    Q GM+++  ++K  +++A+ 
Sbjct: 6   VRTSFAAAHSIKGYDGPCSRM--HGHTWLVEAVLRGGQLDQKGMLVDFKEVKNILRSAVG 63

Query: 258 EPLDHKNLDNDVPYF--KTMASTTENVAIYVWDQLQ 359
           E LDH+NL+   P+      + T EN+A Y++ +++
Sbjct: 64  E-LDHQNLNEIKPFAGGSGDSPTAENIARYLFCRIK 98


>UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=14; Bacteroidetes|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Robiginitalea biformata HTCC2501
          Length = 151

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKG-PVDP----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 287
           GKC N   HGH+Y + VTV G P+      + GMVM+  DLKK ++  +++  DH  + N
Sbjct: 23  GKCRNV--HGHSYHLSVTVIGTPIAEDGAVKLGMVMDFGDLKKVVREEVVDRFDHATIFN 80

Query: 288 -DVPYFKTMASTTE 326
            + P+ + +A T E
Sbjct: 81  RNTPHVE-LARTLE 93


>UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=21; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Haemophilus influenzae
          Length = 141

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPV---DPQTGMVMNITDLKKYIKTAILEPLDH 272
           GKC N   HGH Y + V + G +     +  MV++ +DLK  +K  IL+P+DH
Sbjct: 21  GKCQNL--HGHTYKLQVEISGDLYKSGAKKAMVIDFSDLKSIVKKVILDPMDH 71


>UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=32; Betaproteobacteria|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosomonas europaea
          Length = 160

 Score = 42.7 bits (96), Expect = 0.013
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 5/49 (10%)
 Frame = +3

Query: 141 NGHGHNYVVLVTVKGPVD-----PQTGMVMNITDLKKYIKTAILEPLDH 272
           N HGH YV+ VT+ G +      P+ GMVM+ +D+K+ I+ A+++  DH
Sbjct: 24  NLHGHRYVLEVTIAGGIIADAGVPEQGMVMDFSDVKRVIREALVDRWDH 72


>UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 138

 Score = 42.7 bits (96), Expect = 0.013
 Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 302
           GKC     HGHN+ V V  +     + GMV++  DL+K +   +    DH+N+ N+V  F
Sbjct: 33  GKCERL--HGHNWRVRVHARASTLNRIGMVIDFADLQKLV-AEVGSRFDHQNV-NEVAPF 88

Query: 303 KTMASTTENVAIYVWDQLQRIMEKPQ----LLHEVKILETEKNHVVYR 434
               +T E +A + + ++ R + + +     +  V + E E +  +YR
Sbjct: 89  DQENTTAELIARFFYREMSRRLAELEGGRVTVARVDVWENEGSLAIYR 136


>UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Archaeoglobus fulgidus|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Archaeoglobus
           fulgidus
          Length = 115

 Score = 42.7 bits (96), Expect = 0.013
 Identities = 27/89 (30%), Positives = 46/89 (51%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHN+ V V + G V  + GMVM+  DLK+ +   + +  DH  L+  +        T+E
Sbjct: 29  HGHNFKVEVEISGKVK-ENGMVMDFFDLKRIVNEVVAK-FDHTLLNEQIE-----IPTSE 81

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETE 413
           N+ + ++ +L    EK   +  V++ E E
Sbjct: 82  NICLRIFSEL---AEKGLNVRRVRVAENE 107


>UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=5;
           Euryarchaeota|Rep: 6-pyruvoyltetrahydropterin synthase -
           Methanosarcina acetivorans
          Length = 120

 Score = 40.7 bits (91), Expect = 0.052
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +3

Query: 120 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 299
           +GKC     HGH Y + V V+G V  + GMV++  DLKK IK   L+  DH  L++ + +
Sbjct: 24  HGKCGRV--HGHTYKIEVVVEGEVR-ENGMVIDFYDLKKGIKET-LQEYDHTLLNDLIEF 79


>UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Cyanobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Synechocystis sp. (strain
           PCC 6803)
          Length = 129

 Score = 40.3 bits (90), Expect = 0.068
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +3

Query: 123 GKCNNPNGH---GHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV 293
           GKC   +GH   G  YV    +K     +TGMVM+ + LK ++   +   LDH  L++ +
Sbjct: 21  GKCRRLHGHSFRGRVYVASDRLK-TTGSETGMVMDFSVLKAHLDPLVKNHLDHYYLNDSL 79

Query: 294 PYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILET 410
                 + T+E +A +++ +L+        LH V++LET
Sbjct: 80  ---GLESPTSEAIAAWIFAKLEEAGVPG--LHSVEVLET 113


>UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 209

 Score = 39.1 bits (87), Expect = 0.16
 Identities = 26/88 (29%), Positives = 43/88 (48%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           H H++ V V VK        ++++  DL+  I   +   L   N+ N+ PYFKT+  T E
Sbjct: 110 HTHDWWVRVWVKARALNHWDVIIDFKDLQDII-VRVCRELHDTNI-NEHPYFKTVNCTAE 167

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILET 410
            V  YV+ Q++  + +   L  V +  T
Sbjct: 168 RVTEYVFKQVESGLPEGVTLDRVHLRRT 195


>UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=2; Aquifex aeolicus|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Aquifex aeolicus
          Length = 162

 Score = 39.1 bits (87), Expect = 0.16
 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 18/117 (15%)
 Frame = +3

Query: 111 KKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL--- 281
           +K   KC N   HGH+YV+ VTV      +  MVM+   +K  +K  ++E +DH  +   
Sbjct: 33  EKPVNKCVNL--HGHSYVLEVTVGSDTLSEQDMVMDFYHVKNALK-GLIEEIDHSFIIDV 89

Query: 282 -DNDVPYFKTMAS--------------TTENVAIYVWDQLQRIMEKPQLLHEVKILE 407
            D   P  K +A               T E +A + +D L++ +E+  LL EVK+++
Sbjct: 90  NDPMYPELKDVAEKYGAMKIFPVEFCPTAEALAKFFYDFLKKRLEEAGLLGEVKVVK 146


>UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Pirellula sp.|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Rhodopirellula baltica
          Length = 137

 Score = 37.9 bits (84), Expect = 0.36
 Identities = 21/50 (42%), Positives = 25/50 (50%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDH 272
           GKC N   HGHNYV+ V V G      G +++   LK   K  I E  DH
Sbjct: 17  GKCQNL--HGHNYVLEVYVTGEEQDAIGRILDFKQLKTRCKNWIDENWDH 64


>UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Limnobacter sp. MED105|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Limnobacter
           sp. MED105
          Length = 116

 Score = 37.9 bits (84), Expect = 0.36
 Identities = 24/76 (31%), Positives = 41/76 (53%)
 Frame = +3

Query: 138 PNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMAS 317
           P  HGH+Y   V  +GP     G V+  + L +++  A+ + LDH  L+  +        
Sbjct: 19  PGLHGHSYTAEVWFEGPATD--GYVVPESLLTQHVG-AVHKRLDHSYLNEFIEL-----P 70

Query: 318 TTENVAIYVWDQLQRI 365
           T+EN+A ++WDQL+ +
Sbjct: 71  TSENIARWIWDQLRPV 86


>UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=21; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Brucella suis
          Length = 121

 Score = 37.5 bits (83), Expect = 0.48
 Identities = 29/98 (29%), Positives = 49/98 (50%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGHNY+V V +  P     G V +  +L   +K  I +  DH++L++ + + +T   T E
Sbjct: 29  HGHNYIVEVELSAPDLDTHGFVRDYHELAA-LKHYIDDTFDHRHLNDVLGHEQT---TAE 84

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRGG 440
            +A + +D        P+ +  V++ ET K    YR G
Sbjct: 85  RLAKHFFDWCH--ARWPE-ISAVRVSETPKTWAEYRPG 119


>UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Staphylococcus
           saprophyticus subsp. saprophyticus (strain ATCC 15305
           /DSM 20229)
          Length = 142

 Score = 37.5 bits (83), Expect = 0.48
 Identities = 18/75 (24%), Positives = 39/75 (52%)
 Frame = +3

Query: 204 GMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 383
           G+ M+  ++ K  +  I   +D + ++  +P   T   T EN+AI++W Q  + + +   
Sbjct: 63  GLAMDFNEVDKLYEREIAPYIDGQLVNETLPEMNT---TAENIAIWIWHQFNKHLPENNS 119

Query: 384 LHEVKILETEKNHVV 428
           L +++  ET+   +V
Sbjct: 120 LQKLEFFETDTQGLV 134


>UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein - delta
           proteobacterium MLMS-1
          Length = 154

 Score = 37.5 bits (83), Expect = 0.48
 Identities = 22/80 (27%), Positives = 42/80 (52%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           H H Y + V + GP   + G +++I +L   +   + E  + + L ND+P F  +  + E
Sbjct: 54  HAHCYRLEVALDGPELNEHGFLVDIVELAGNLDL-VQEAYEDRIL-NDLPEFAGLNPSIE 111

Query: 327 NVAIYVWDQLQRIMEKPQLL 386
           N+A  +W +L ++    +LL
Sbjct: 112 NLARLIWQRLSQLPASDKLL 131


>UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4;
           Comamonadaceae|Rep: Putative uncharacterized protein -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 120

 Score = 37.1 bits (82), Expect = 0.64
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDN 287
           HGH Y   V V G  D  TGMVM++  +++ I   + E LDH  LD+
Sbjct: 30  HGHTYNAEVFVAGEPDEATGMVMDLGLVRREI-AVLREELDHHLLDD 75


>UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 178

 Score = 36.7 bits (81), Expect = 0.84
 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 19/117 (16%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPV-----DPQTGMVMNITDLKKYIKTAILEPLDH-----KNLDNDVP 296
           HGH  V++ TV+GPV     D + GMV++   L++ +   I + LDH     K    D+ 
Sbjct: 62  HGHRGVIVATVEGPVIDRAGDAEEGMVIDFKFLRQIMDEHIHDQLDHGFAVWKEDKEDLE 121

Query: 297 YF-----KTMAS----TTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYRGG 440
           +      + + +    T E +A + ++Q+   + +  +L  ++  ET  N   Y GG
Sbjct: 122 FILKRNTRVLVTDAPPTAECLARWAFNQISGKLPEGVILKNLRWYETPNNWADYTGG 178


>UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyl tetrahydropterin synthase -
           Roseobacter sp. CCS2
          Length = 131

 Score = 36.7 bits (81), Expect = 0.84
 Identities = 23/71 (32%), Positives = 39/71 (54%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HG  +VV          + G+V+++    + +  A L+PL + NLD +VP FK   +TTE
Sbjct: 28  HGATFVVDAAFYTKDLDENGLVVDMGLALEALADA-LKPLKYANLD-EVPAFKGKITTTE 85

Query: 327 NVAIYVWDQLQ 359
            +  ++W QL+
Sbjct: 86  FLCHHIWQQLR 96


>UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           6-pyruvoyl tetrahydrobiopterin synthase, putative -
           Oceanicaulis alexandrii HTCC2633
          Length = 132

 Score = 36.7 bits (81), Expect = 0.84
 Identities = 23/74 (31%), Positives = 43/74 (58%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH++   VT+ G    ++GMV +  +++  I   I E LDH+ L NDV   +    + E
Sbjct: 41  HGHSFAGTVTLTGSRAAESGMVKDFWEIEAEI-NKIREQLDHRLL-NDVEGLE--HPSLE 96

Query: 327 NVAIYVWDQLQRIM 368
            +A +V+++L++ +
Sbjct: 97  AIAYWVFERLEKTL 110


>UniRef50_A7BS03 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Beggiatoa sp. PS|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Beggiatoa sp. PS
          Length = 148

 Score = 35.1 bits (77), Expect = 2.6
 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV-PY 299
           GKC +   HGH+   ++ +        G VM+  D+K  +K  I +  DH  L N+  P 
Sbjct: 23  GKCRHV--HGHSGEAIIELASNTLNDNGFVMDFADVKTPLKKWINQFWDHAYLANESDPL 80

Query: 300 FKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVYR 434
                S   N+  +  +    +M +  L  +  ILE     ++ R
Sbjct: 81  LPAFKSENMNIYTFPEEPTAEVMAR-HLFEQAAILERPPGVILTR 124


>UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1;
           Nocardioides sp. JS614|Rep: Putative uncharacterized
           protein - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 118

 Score = 35.1 bits (77), Expect = 2.6
 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 3/105 (2%)
 Frame = +3

Query: 123 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILE---PLDHKNLDNDV 293
           GKC+    HGH+YV+ V V G +D + G+VM+  ++   +   +LE    LDH +L+  +
Sbjct: 22  GKCSRI--HGHSYVLEVHVTGELDDR-GVVMDFAEVDAIVDQHVLEGPAGLDHVDLNALL 78

Query: 294 PYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVV 428
                   T E VA+++ ++L        +L   ++ ETE   VV
Sbjct: 79  E-----NPTAELVAVHIGERLDAAGLSWTML---RLWETEDGSVV 115


>UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase,
           putative; n=6; Plasmodium|Rep: 6-pyruvoyl
           tetrahydropterin synthase, putative - Plasmodium
           chabaudi
          Length = 173

 Score = 35.1 bits (77), Expect = 2.6
 Identities = 18/43 (41%), Positives = 26/43 (60%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK 275
           HGHNY V + VKG +    G V++ + LKK +K  I   +DH+
Sbjct: 41  HGHNYNVSLKVKGHIQ-SDGYVVDFSILKKIVKN-ICNTIDHR 81


>UniRef50_A7AMF5 Cluster: Rab7; n=2; Babesia bovis|Rep: Rab7 -
           Babesia bovis
          Length = 233

 Score = 34.7 bits (76), Expect = 3.4
 Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
 Frame = +3

Query: 159 YVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAI 338
           +++ V  K P      ++ N  D     K +  +  +    +ND+P+F+T A T +NVA 
Sbjct: 123 FLIQVEPKDPESFPFALIGNKVDDVANRKVSANKATNWCKANNDIPHFETSAKTAQNVAA 182

Query: 339 YVWDQLQRIMEKPQLLHEVKILET---EKNHVVYRGGN 443
              +  ++ + +     E+ I +T   ++ HV + G N
Sbjct: 183 AFMEIAKKAVMRDTQDDEIYIPDTLLLDQRHVQHTGNN 220


>UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Euryarchaeota|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Methanobacterium
           thermoautotrophicum
          Length = 161

 Score = 34.7 bits (76), Expect = 3.4
 Identities = 25/90 (27%), Positives = 40/90 (44%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 326
           HGH+Y+V V V+G    + G V +  D+K  ++  I    DHK L           STT 
Sbjct: 33  HGHSYIVDVKVEGKRSGKHGFVADFKDVKDIVR-RICSEFDHKLLIPLRNPLINFTSTTR 91

Query: 327 NVAIYVWDQLQRIMEKPQLLHEVKILETEK 416
            V   +  +   I E+   L +++    E+
Sbjct: 92  TVKFEIAGKKYSIPEEDCCLMDLESSSAEE 121


>UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1;
           Halorhodospira halophila SL1|Rep: Putative
           uncharacterized protein - Halorhodospira halophila
           (strain DSM 244 / SL1) (Ectothiorhodospirahalophila
           (strain DSM 244 / SL1))
          Length = 258

 Score = 34.3 bits (75), Expect = 4.5
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = +3

Query: 147 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 284
           HGH Y + V V  P+D   G  ++  D+K      + E LDH+ LD
Sbjct: 168 HGHGYRLRVHVTAPLDRVLGWTLDYGDVKAAF-APVREALDHQRLD 212


>UniRef50_Q98S03 Cluster: Putative uncharacterized protein orf305;
           n=1; Guillardia theta|Rep: Putative uncharacterized
           protein orf305 - Guillardia theta (Cryptomonas phi)
          Length = 305

 Score = 34.3 bits (75), Expect = 4.5
 Identities = 15/62 (24%), Positives = 32/62 (51%)
 Frame = -1

Query: 272 MVEWFQDGCFYVFLEVSYIHHHTSLRIYRTLYCYKNNIIMTVTIRIVAFTINFFVLFVT* 93
           ++ ++    F++F + SY    +   +++ ++ +K NII    +    F I FF +F T 
Sbjct: 229 LISYYLIDFFHIFKKYSYKLIFSKCIVFKNIFKFKQNIIFVKKLYCEEFLIKFFTIFKTR 288

Query: 92  KR 87
           +R
Sbjct: 289 RR 290


>UniRef50_Q7RDH2 Cluster: CCAAT-box DNA binding protein subunit B,
            putative; n=2; Plasmodium (Vinckeia)|Rep: CCAAT-box DNA
            binding protein subunit B, putative - Plasmodium yoelii
            yoelii
          Length = 1413

 Score = 34.3 bits (75), Expect = 4.5
 Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = +3

Query: 534  ILNVFIMKNILYYYC*VMYTFLK*DRSKKLIFIRIKLKHYNYIY--YVPK 677
            IL +   KNI  YY    Y  L  + +  + FI IK K YNYIY  YV K
Sbjct: 974  ILQINAFKNIFLYYLRDSYFTLFNNLTNDINFIEIKNKLYNYIYNSYVQK 1023


>UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_03001749;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001749 - Ferroplasma acidarmanus fer1
          Length = 157

 Score = 33.9 bits (74), Expect = 5.9
 Identities = 18/50 (36%), Positives = 29/50 (58%)
 Frame = +3

Query: 126 KCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK 275
           KC N   HGH+Y + V +       +GM ++ T +K+ IK  ++E +DHK
Sbjct: 26  KCKN--FHGHDYSIDVIIDSDGVKASGMAIDFTIVKQAIK-PVIENMDHK 72


>UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin
           synthase; n=1; Chromobacterium violaceum|Rep: Probable
           6-pyruvoyltetrahydrobiopterin synthase - Chromobacterium
           violaceum
          Length = 239

 Score = 33.5 bits (73), Expect = 7.8
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +3

Query: 141 NGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 284
           N  GH+Y+V + + G +D   G +++  D+K   K  I   LDH  LD
Sbjct: 139 NYTGHSYLVRLMLSGGIDRTMGWLLDFGDVKDRFK-PIYRQLDHNPLD 185


>UniRef50_Q97UC3 Cluster: Putative uncharacterized protein; n=1;
           Sulfolobus solfataricus|Rep: Putative uncharacterized
           protein - Sulfolobus solfataricus
          Length = 334

 Score = 33.5 bits (73), Expect = 7.8
 Identities = 18/52 (34%), Positives = 32/52 (61%)
 Frame = -1

Query: 254 DGCFYVFLEVSYIHHHTSLRIYRTLYCYKNNIIMTVTIRIVAFTINFFVLFV 99
           +G FY++L V+YI ++T  RI   +  ++ N+ +T+TI   + T  F  LF+
Sbjct: 85  NGSFYLYLPVAYIQNNT--RINVIINSFQKNVNLTLTIPNSSTTFAFSSLFL 134


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 733,870,086
Number of Sequences: 1657284
Number of extensions: 14149027
Number of successful extensions: 32556
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 31289
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32507
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 85260991088
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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