Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_pT_D21
(855 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11 pr... 48 6e-05
BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic recombina... 48 6e-05
AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic recombina... 48 6e-05
AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 1... 48 6e-05
AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11 ... 48 6e-05
AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and r... 48 6e-05
BC017823-1|AAH17823.1| 517|Homo sapiens Unknown (protein for IM... 44 7e-04
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 32 2.3
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 32 2.3
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 30 9.3
BC031621-1|AAH31621.1| 401|Homo sapiens Rab interacting lysosom... 30 9.3
BC004961-1|AAH04961.1| 348|Homo sapiens RILP protein protein. 30 9.3
AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating p... 30 9.3
AL050195-1|CAB43313.1| 246|Homo sapiens hypothetical protein pr... 30 9.3
AK055755-1|BAB71003.1| 401|Homo sapiens protein ( Homo sapiens ... 30 9.3
AJ404317-1|CAC33443.1| 401|Homo sapiens rab interacting lysosom... 30 9.3
AJ278711-1|CAC82174.1| 401|Homo sapiens hypothetical protein pr... 30 9.3
AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating ... 30 9.3
>U37359-1|AAC78721.1| 680|Homo sapiens MRE11 homologue hMre11
protein.
Length = 680
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>BC063458-1|AAH63458.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>AY584241-1|AAS79320.1| 708|Homo sapiens MRE11 meiotic
recombination 11 homolog A (S. cerevisiae) protein.
Length = 708
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>AF303395-1|AAK18790.1| 708|Homo sapiens meiotic recombination 11
protein.
Length = 708
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>AF073362-1|AAC36249.1| 708|Homo sapiens endo/exonuclease Mre11
protein.
Length = 708
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>AF022778-1|AAD10197.1| 708|Homo sapiens DNA recombination and
repair protein protein.
Length = 708
Score = 47.6 bits (108), Expect = 6e-05
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 7/167 (4%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRC 501
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D + +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT 481
Query: 500 IAALLESTAET-EKEIAEQL----EVCKRELDEADDEKLHTLVDASA 375
L E + E +I E++ E ++ +E DDE + A A
Sbjct: 482 QRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARA 528
>BC017823-1|AAH17823.1| 517|Homo sapiens Unknown (protein for
IMAGE:4687479) protein.
Length = 517
Score = 44.0 bits (99), Expect = 7e-04
Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = -2
Query: 854 IRLSIFYERXSQNFNRIRFGQNFXGLVANXNDLLIMKXXXKIRXXRXCDPEEEGDMTGVA 675
+RL + Y + F+ +RF Q F VAN D +I + + + + G +
Sbjct: 363 VRLRVDYSGGFEPFSVLRFSQKFVDRVANPKD-IIHFFRHREQKEKTGEEINFGKLITKP 421
Query: 674 AEAAD--VESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVL 534
+E VE L++ Y++ K+ +LS+L+ R + +AV++F K +D +
Sbjct: 422 SEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAI 470
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 32.3 bits (70), Expect = 2.3
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = -2
Query: 653 SLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTA 474
+LL A D+ +S +S+ I + + +DVL F + K + ++ LL
Sbjct: 509 TLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTF-SQKHKELSVLLLEMK 567
Query: 473 ETEKEIAE-QLEVCKRELDEADDEKL 399
E ++EIA +L++ + +EAD E L
Sbjct: 568 EAQEEIAFLKLQLQGKRAEEADHEVL 593
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372
protein.
Length = 3225
Score = 32.3 bits (70), Expect = 2.3
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = -2
Query: 653 SLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTA 474
+LL A D+ +S +S+ I + + +DVL F + K + ++ LL
Sbjct: 475 TLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTF-SQKHKELSVLLLEMK 533
Query: 473 ETEKEIAE-QLEVCKRELDEADDEKL 399
E ++EIA +L++ + +EAD E L
Sbjct: 534 EAQEEIAFLKLQLQGKRAEEADHEVL 559
>BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein.
Length = 997
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = -2
Query: 542 DVLRRAFDAHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDE 405
D L + K++ I A E E+E A+ E+C+RELD+A+ E
Sbjct: 810 DALNKELLMTKQKLIDAE-EEKRRLEEESAQLKEMCRRELDKAESE 854
>BC031621-1|AAH31621.1| 401|Homo sapiens Rab interacting lysosomal
protein protein.
Length = 401
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/82 (23%), Positives = 36/82 (43%)
Frame = -2
Query: 647 LRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTAET 468
LR A P+++R + ++ +TD RD HN D+ +R + + L+
Sbjct: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQR---GQETEALQEQLQRLLLV 154
Query: 467 EKEIAEQLEVCKRELDEADDEK 402
E+ +L + +L A D +
Sbjct: 155 NAELRHKLAAMQTQLRAAQDRE 176
>BC004961-1|AAH04961.1| 348|Homo sapiens RILP protein protein.
Length = 348
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/82 (23%), Positives = 36/82 (43%)
Frame = -2
Query: 647 LRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTAET 468
LR A P+++R + ++ +TD RD HN D+ +R + + L+
Sbjct: 45 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQR---GQETEALQEQLQRLLLV 101
Query: 467 EKEIAEQLEVCKRELDEADDEK 402
E+ +L + +L A D +
Sbjct: 102 NAELRHKLAAMQTQLRAAQDRE 123
>AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating
protein 1 protein.
Length = 997
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = -2
Query: 542 DVLRRAFDAHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDE 405
D L + K++ I A E E+E A+ E+C+RELD+A+ E
Sbjct: 810 DALNKELLMTKQKLIDAE-EEKRRLEEESAQLKEMCRRELDKAESE 854
>AL050195-1|CAB43313.1| 246|Homo sapiens hypothetical protein
protein.
Length = 246
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = -2
Query: 542 DVLRRAFDAHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDE 405
D L + K++ I A E E+E A+ E+C+RELD+A+ E
Sbjct: 59 DALNKELLMTKQKLIDAE-EEKRRLEEESAQLKEMCRRELDKAESE 103
>AK055755-1|BAB71003.1| 401|Homo sapiens protein ( Homo sapiens
cDNA FLJ31193 fis, clone KIDNE2000497, weakly similar to
TRICHOHYALIN. ).
Length = 401
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/82 (23%), Positives = 36/82 (43%)
Frame = -2
Query: 647 LRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTAET 468
LR A P+++R + ++ +TD RD HN D+ +R + + L+
Sbjct: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQR---GQETEALQEQLQRLLLV 154
Query: 467 EKEIAEQLEVCKRELDEADDEK 402
E+ +L + +L A D +
Sbjct: 155 NAELRHKLAAMQTQLRAAQDRE 176
>AJ404317-1|CAC33443.1| 401|Homo sapiens rab interacting lysosomal
protein protein.
Length = 401
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/82 (23%), Positives = 36/82 (43%)
Frame = -2
Query: 647 LRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTAET 468
LR A P+++R + ++ +TD RD HN D+ +R + + L+
Sbjct: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQR---GQETEALQEQLQRLLLV 154
Query: 467 EKEIAEQLEVCKRELDEADDEK 402
E+ +L + +L A D +
Sbjct: 155 NAELRHKLAAMQTQLRAAQDRE 176
>AJ278711-1|CAC82174.1| 401|Homo sapiens hypothetical protein
protein.
Length = 401
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/82 (23%), Positives = 36/82 (43%)
Frame = -2
Query: 647 LRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFDAHKRRCIAALLESTAET 468
LR A P+++R + ++ +TD RD HN D+ +R + + L+
Sbjct: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQR---GQETEALQEQLQRLLLV 154
Query: 467 EKEIAEQLEVCKRELDEADDEK 402
E+ +L + +L A D +
Sbjct: 155 NAELRHKLAAMQTQLRAAQDRE 176
>AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating
protein, GAPCenA protein.
Length = 997
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = -2
Query: 542 DVLRRAFDAHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDE 405
D L + K++ I A E E+E A+ E+C+RELD+A+ E
Sbjct: 810 DALNKELLMTKQKLIDAE-EEKRRLEEESAQLKEMCRRELDKAESE 854
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,764,201
Number of Sequences: 237096
Number of extensions: 1684819
Number of successful extensions: 4573
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4573
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10872716010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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