Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_pT_C16
(854 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 85 3e-16
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 85 3e-16
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 85 3e-16
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 85 3e-16
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 85 3e-16
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 85 3e-16
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 85 3e-16
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 85 3e-16
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 85 3e-16
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 85 3e-16
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 85 3e-16
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 85 3e-16
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 85 3e-16
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 85 4e-16
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 85 4e-16
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 83 9e-16
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 80 9e-15
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 80 9e-15
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 80 9e-15
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 80 9e-15
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 80 1e-14
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 73 1e-12
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 73 1e-12
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 73 1e-12
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 73 1e-12
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 73 1e-12
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 73 1e-12
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 73 1e-12
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 73 1e-12
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 73 1e-12
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 73 1e-12
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 73 1e-12
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 71 7e-12
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 71 7e-12
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 71 7e-12
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 70 1e-11
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 70 1e-11
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 70 1e-11
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 70 1e-11
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 69 2e-11
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 69 2e-11
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 69 3e-11
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 68 4e-11
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 68 4e-11
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 68 4e-11
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 68 4e-11
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 67 7e-11
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 67 7e-11
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 67 7e-11
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 64 5e-10
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 64 5e-10
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 64 8e-10
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 64 8e-10
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 64 8e-10
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 64 8e-10
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 63 1e-09
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 63 1e-09
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 62 2e-09
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 62 2e-09
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 62 2e-09
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 62 2e-09
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 62 2e-09
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 62 2e-09
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 62 2e-09
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 62 2e-09
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 62 2e-09
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 62 2e-09
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 62 2e-09
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 62 2e-09
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 62 2e-09
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 62 2e-09
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 62 2e-09
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 62 2e-09
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 62 2e-09
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 62 3e-09
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 62 3e-09
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 62 3e-09
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 62 3e-09
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 60 1e-08
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 60 1e-08
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 60 1e-08
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 60 1e-08
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 60 1e-08
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 60 1e-08
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 60 1e-08
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 60 1e-08
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 60 1e-08
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 59 2e-08
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 59 2e-08
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 59 2e-08
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 59 2e-08
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 59 2e-08
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 58 3e-08
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 58 3e-08
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 58 3e-08
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 58 3e-08
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 58 3e-08
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 58 3e-08
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 56 1e-07
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 56 1e-07
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 56 1e-07
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 56 1e-07
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 56 2e-07
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 56 2e-07
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 56 2e-07
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 55 3e-07
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 55 3e-07
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 55 3e-07
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 55 3e-07
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 55 3e-07
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 55 3e-07
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 55 3e-07
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 55 3e-07
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 55 3e-07
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 55 3e-07
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 55 3e-07
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 55 3e-07
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 55 3e-07
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 54 7e-07
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 53 2e-06
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 52 2e-06
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 52 3e-06
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 52 4e-06
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 51 5e-06
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 51 5e-06
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 51 5e-06
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 51 5e-06
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 51 5e-06
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 51 5e-06
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 51 5e-06
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 51 5e-06
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 51 5e-06
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 51 5e-06
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 51 5e-06
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 51 5e-06
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 51 5e-06
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 51 5e-06
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 51 5e-06
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 51 5e-06
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 51 5e-06
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 51 5e-06
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 51 5e-06
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 51 5e-06
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 51 5e-06
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 51 5e-06
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 51 5e-06
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 51 5e-06
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 51 5e-06
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 51 5e-06
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 51 5e-06
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 51 5e-06
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 46 5e-06
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 51 6e-06
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 50 1e-05
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 50 1e-05
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 50 1e-05
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 50 1e-05
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 50 1e-05
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 44 1e-05
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 49 2e-05
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 49 2e-05
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 49 2e-05
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 49 2e-05
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 49 2e-05
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 49 2e-05
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 49 2e-05
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 49 2e-05
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 49 2e-05
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 49 2e-05
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 48 3e-05
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 48 3e-05
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 48 3e-05
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 48 3e-05
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 48 4e-05
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 48 4e-05
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 48 4e-05
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 48 4e-05
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 48 4e-05
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 48 4e-05
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 48 4e-05
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 48 4e-05
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 48 4e-05
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 48 4e-05
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 48 4e-05
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 48 4e-05
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 48 4e-05
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 48 4e-05
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 48 6e-05
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 48 6e-05
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 48 6e-05
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 48 6e-05
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 48 6e-05
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 48 6e-05
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 48 6e-05
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 48 6e-05
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 48 6e-05
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 48 6e-05
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 48 6e-05
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 47 8e-05
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 47 8e-05
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 47 8e-05
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 47 8e-05
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 47 8e-05
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 47 8e-05
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 47 8e-05
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 47 8e-05
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 47 1e-04
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 47 1e-04
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 47 1e-04
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 46 1e-04
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 46 1e-04
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 46 1e-04
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 46 1e-04
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 46 2e-04
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 46 2e-04
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 45 3e-04
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 45 3e-04
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 45 3e-04
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 5e-04
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 44 7e-04
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 44 7e-04
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 44 7e-04
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 44 7e-04
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 44 7e-04
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 44 7e-04
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 44 7e-04
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 7e-04
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 44 7e-04
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 44 7e-04
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 44 7e-04
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 44 7e-04
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 44 7e-04
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 44 7e-04
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 44 7e-04
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 44 7e-04
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 44 7e-04
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 44 7e-04
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 44 7e-04
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 44 7e-04
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 44 7e-04
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 44 7e-04
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 44 7e-04
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 44 7e-04
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 44 7e-04
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 44 7e-04
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 44 7e-04
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 44 7e-04
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 44 7e-04
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 44 7e-04
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 44 7e-04
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 44 7e-04
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 44 0.001
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 44 0.001
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 44 0.001
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 44 0.001
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 44 0.001
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 44 0.001
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 44 0.001
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 44 0.001
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 44 0.001
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 44 0.001
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 44 0.001
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 44 0.001
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 43 0.001
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 43 0.001
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 43 0.001
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 42 0.002
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 42 0.002
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 42 0.002
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 42 0.002
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 42 0.002
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 42 0.003
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 42 0.003
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 42 0.003
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 42 0.003
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 42 0.003
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 42 0.003
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 42 0.003
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 42 0.003
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 42 0.003
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 42 0.003
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 42 0.003
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 42 0.003
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 42 0.004
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 41 0.005
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 41 0.005
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 41 0.005
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 41 0.005
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 41 0.005
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 41 0.007
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 41 0.007
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 40 0.009
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 40 0.009
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 40 0.009
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 40 0.009
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 40 0.012
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 40 0.012
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 40 0.012
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 40 0.012
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 40 0.012
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 40 0.012
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 39 0.020
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 39 0.020
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 39 0.020
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 39 0.020
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 39 0.020
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 39 0.020
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 39 0.020
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 39 0.027
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 38 0.046
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 37 0.081
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 37 0.081
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 37 0.081
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 37 0.081
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 37 0.081
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 37 0.081
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 37 0.11
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 37 0.11
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 37 0.11
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 37 0.11
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 36 0.14
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 36 0.14
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 36 0.25
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 35 0.33
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 35 0.43
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 35 0.43
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 35 0.43
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 35 0.43
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 35 0.43
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 35 0.43
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 35 0.43
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 35 0.43
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 35 0.43
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 35 0.43
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 34 0.76
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 34 0.76
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 34 0.76
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 34 0.76
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 34 0.76
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 34 0.76
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 34 0.76
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 34 0.76
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 34 0.76
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 33 1.0
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 33 1.3
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 33 1.7
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 33 1.7
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 33 1.7
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 33 1.7
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 33 1.7
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 33 1.7
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 33 1.7
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 33 1.7
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 33 1.7
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 32 3.1
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 32 3.1
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 32 3.1
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 31 4.0
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 30 9.3
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 30 9.3
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACL 537
E+L+AG+DT S T L++L+ + ++Q+ L EE+ + + + +A L
Sbjct: 330 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 389
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL VVP N R ++ V G+ PK + + +SR + PE F P RWL
Sbjct: 390 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 449
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
S P HP ++PFG+GVR+C
Sbjct: 450 -RNSQPATPRIQHPFGSVPFGYGVRAC 475
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACL 537
E+L+AG+DT S T L++L+ + ++Q+ L EE+ + + + +A L
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL VVP N R ++ V G+ PK + + +SR + PE F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
S P HP ++PFG+GVR+C
Sbjct: 451 -RNSQPATPRIQHPFGSVPFGYGVRAC 476
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACL 537
E+L+AG+DT S T L++L+ + ++Q+ L EE+ + + + +A L
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL VVP N R ++ V G+ PK + + +SR + PE F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
S P HP ++PFG+GVR+C
Sbjct: 451 -RNSQPATPRIQHPFGSVPFGYGVRAC 476
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACL 537
E+L+AG+DT S T L++L+ + ++Q+ L EE+ + + + +A L
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL VVP N R ++ V G+ PK + + +SR + PE F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
S P HP ++PFG+GVR+C
Sbjct: 451 -RNSQPATPRIQHPFGSVPFGYGVRAC 476
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYKR--------YFR 546
+E+LLAG+DTVS + L+ L+ + +VQ L EI + S Y +
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 545 ACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPE 366
A +KE LRL VVP N R +D VG Y IPK V + SR +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 365 RWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
RWL E P HP +LPFGFG RSC
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSC 455
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 84.6 bits (200), Expect = 4e-16
Identities = 56/148 (37%), Positives = 77/148 (52%), Gaps = 10/148 (6%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRAC 540
+EMLLAG+DT SF + ++ LA + +VQ + EI ++ RA
Sbjct: 175 TEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRAL 234
Query: 539 LKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERW 360
LKE LRL V+P N R T D ++GGY IPKG + + S ++ +PR + F PERW
Sbjct: 235 LKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERW 294
Query: 359 LVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L K D ++PFG GVRSC
Sbjct: 295 L-RKGD---LDRVDNFGSIPFGHGVRSC 318
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 84.6 bits (200), Expect = 4e-16
Identities = 56/148 (37%), Positives = 77/148 (52%), Gaps = 10/148 (6%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRAC 540
+EMLLAG+DT SF + ++ LA + +VQ + EI ++ RA
Sbjct: 175 TEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRAL 234
Query: 539 LKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERW 360
LKE LRL V+P N R T D ++GGY IPKG + + S ++ +PR + F PERW
Sbjct: 235 LKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERW 294
Query: 359 LVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L K D ++PFG GVRSC
Sbjct: 295 L-RKGD---LDRVDNFGSIPFGHGVRSC 318
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 83.4 bits (197), Expect = 9e-16
Identities = 50/147 (34%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACL 537
E+L+AG+DT S T L++L+ + ++Q L EE+ + + + +A L
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL VVP N R ++ V G+ PK + + +SR + PE F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFSEPESFQPHRWL 450
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
S P HP ++PFG+GVR+C
Sbjct: 451 -RNSQPATPRIQHPFGSVPFGYGVRAC 476
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 80.2 bits (189), Expect = 9e-15
Identities = 52/158 (32%), Positives = 79/158 (50%), Gaps = 10/158 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 54 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 113
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE +
Sbjct: 114 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 173
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PERWL EK +P LPFG G R C
Sbjct: 174 DSSQFRPERWLQEKE------KINPFAHLPFGVGKRMC 205
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 80.2 bits (189), Expect = 9e-15
Identities = 52/158 (32%), Positives = 79/158 (50%), Gaps = 10/158 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 288
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PERWL EK +P LPFG G R C
Sbjct: 289 DSSQFRPERWLQEKE------KINPFAHLPFGVGKRMC 320
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 80.2 bits (189), Expect = 9e-15
Identities = 52/158 (32%), Positives = 79/158 (50%), Gaps = 10/158 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE +
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 430
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PERWL EK +P LPFG G R C
Sbjct: 431 DSSQFRPERWLQEKE------KINPFAHLPFGVGKRMC 462
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 80.2 bits (189), Expect = 9e-15
Identities = 52/158 (32%), Positives = 79/158 (50%), Gaps = 10/158 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 288
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PERWL EK +P LPFG G R C
Sbjct: 289 DSSQFRPERWLQEKE------KINPFAHLPFGVGKRMC 320
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/158 (32%), Positives = 78/158 (49%), Gaps = 10/158 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI--------RTSESN 564
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI R E +
Sbjct: 310 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREED 369
Query: 563 YKR--YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
+ Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE +
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 429
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PERWL EK +P LPFG G R C
Sbjct: 430 DSSQFRPERWLQEKE------KINPFAHLPFGVGKRMC 461
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 139 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 198
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 199 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 258
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 259 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 292
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 216 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 275
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 276 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 335
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 336 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 369
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG+ V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 70.5 bits (165), Expect = 7e-12
Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 442
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 349
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG V+ P+ L R K++
Sbjct: 350 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 409
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 410 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 443
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 70.5 bits (165), Expect = 7e-12
Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 349
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG V+ P+ L R K++
Sbjct: 350 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 409
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P + PFG G R+C
Sbjct: 410 TEPEKFLPERFSKKNKD-----NIDPYIYTPFGSGPRNC 443
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/145 (31%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKE 531
+ AG +T S V + +++ LA + VQ K+++EI T N Y + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG+ V+ P+ L K++ PE F+PER+ +
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
D N P + PFG G R+C
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNC 442
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/145 (31%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKE 531
+ AG +T S V + +++ LA + VQ K+++EI T N Y + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG+ V+ P+ L K++ PE F+PER+ +
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
D N P + PFG G R+C
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNC 442
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/145 (31%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKE 531
+ AG +T S V + +++ LA + VQ K+++EI T N Y + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG+ V+ P+ L K++ PE F+PER+ +
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
D N P + PFG G R+C
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNC 442
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/145 (31%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKE 531
+ AG +T S V + +++ LA + VQ K+++EI T N Y + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG+ V+ P+ L K++ PE F+PER+ +
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
D N P + PFG G R+C
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNC 442
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 69.3 bits (162), Expect = 2e-11
Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG V+ P+ L R K++
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P PFG G R+C
Sbjct: 409 TEPEKFLPERFSKKNKD-----NIDPYTYTPFGSGPRNC 442
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 69.3 bits (162), Expect = 2e-11
Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + + AG +T S V + +++ LA + VQ KL+EEI N
Sbjct: 288 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 347
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL + R +D + G +IPKG V+ P+ L R K++
Sbjct: 348 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 407
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F+PER+ + D N P PFG G R+C
Sbjct: 408 TEPEKFLPERFSKKNKD-----NIDPYTYTPFGSGPRNC 441
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 56/167 (33%), Positives = 79/167 (47%), Gaps = 12/167 (7%)
Frame = -1
Query: 740 VLEKLIAIDEKVAVMMASEM-LLAG-IDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSES 567
V E L+ + + + A+ M L AG +DT +F LF LA N VQ LR+E + +
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAA 349
Query: 566 NYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEY 417
+ + RA LKE LRL V R D ++ Y+IP G V
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 416 LSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L R+ +PRPE + P+RWL + G+ L +PFGFG+R C
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNLHHVPFGFGMRQC 450
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 68.1 bits (159), Expect = 4e-11
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Frame = -1
Query: 758 PEEEXSVLEKLIAIDEKV--AVMMASEMLLAG-IDTVSFVTTSLLFNLAMNQKVQDKLRE 588
P++ S++ +L+ E A+ S L AG +DT F LF LA N VQ LR+
Sbjct: 283 PQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQ 342
Query: 587 EIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGID 438
E + ++ + RA LKE LRL V R D ++ Y+IP G
Sbjct: 343 ESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTL 402
Query: 437 VIAPNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
V L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 403 VRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 68.1 bits (159), Expect = 4e-11
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Frame = -1
Query: 758 PEEEXSVLEKLIAIDEKV--AVMMASEMLLAG-IDTVSFVTTSLLFNLAMNQKVQDKLRE 588
P++ S++ +L+ E A+ S L AG +DT F LF LA N VQ LR+
Sbjct: 283 PQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQ 342
Query: 587 EIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGID 438
E + ++ + RA LKE LRL V R D ++ Y+IP G
Sbjct: 343 ESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTL 402
Query: 437 VIAPNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
V L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 403 VRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 68.1 bits (159), Expect = 4e-11
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Frame = -1
Query: 758 PEEEXSVLEKLIAIDEKV--AVMMASEMLLAG-IDTVSFVTTSLLFNLAMNQKVQDKLRE 588
P++ S++ +L+ E A+ S L AG +DT F LF LA N VQ LR+
Sbjct: 283 PQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQ 342
Query: 587 EIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGID 438
E + ++ + RA LKE LRL V R D ++ Y+IP G
Sbjct: 343 ESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTL 402
Query: 437 VIAPNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
V L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 403 VRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 68.1 bits (159), Expect = 4e-11
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Frame = -1
Query: 758 PEEEXSVLEKLIAIDEKV--AVMMASEMLLAG-IDTVSFVTTSLLFNLAMNQKVQDKLRE 588
P++ S++ +L+ E A+ S L AG +DT F LF LA N VQ LR+
Sbjct: 354 PQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQ 413
Query: 587 EIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGID 438
E + ++ + RA LKE LRL V R D ++ Y+IP G
Sbjct: 414 ESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTL 473
Query: 437 VIAPNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
V L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 474 VRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 521
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/167 (32%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Frame = -1
Query: 740 VLEKLIAIDEKVAVMMASEM-LLAG-IDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSES 567
V E L+ + + + A+ M L AG +DT +F LF LA N VQ LR+E + +
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAA 349
Query: 566 NYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEY 417
+ + RA LKE LRL V R D ++ Y+IP G V
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 416 LSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNFHHVPFGFGMRQC 450
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 67.3 bits (157), Expect = 7e-11
Identities = 55/167 (32%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Frame = -1
Query: 740 VLEKLIAIDEKVAVMMASEM-LLAG-IDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSES 567
V E L+ + + + A+ M L AG +DT +F LF LA N VQ LR+E + +
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAA 349
Query: 566 NYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEY 417
+ + RA LKE LRL V R D ++ Y+IP G V
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 416 LSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNFHHVPFGFGMRQC 450
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 67.3 bits (157), Expect = 7e-11
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Frame = -1
Query: 758 PEEEXSVLEKLIAIDEKV--AVMMASEMLLAG-IDTVSFVTTSLLFNLAMNQKVQDKLRE 588
P++ S++ +L+ E A+ S L AG +DT F LF LA N VQ LR+
Sbjct: 283 PQQYTSIVAELLLNAELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQ 342
Query: 587 EIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGID 438
E + ++ + RA LKE LRL V R D ++ Y+IP G
Sbjct: 343 ESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTL 402
Query: 437 VIAPNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
V L R+ +PRPE + P+RWL + G+ +PFGFG+R C
Sbjct: 403 VRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 64.5 bits (150), Expect = 5e-10
Identities = 48/147 (32%), Positives = 64/147 (43%), Gaps = 10/147 (6%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKRY----------FRACL 537
E+ +D F LF LA N VQ LR+E ++ + RA L
Sbjct: 100 ELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASISEHPQKATTELPLLRAAL 159
Query: 536 KEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
KE LRL V R D ++ Y+IP G V L R+ +PRPE + P+RWL
Sbjct: 160 KETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 219
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
K G+ +PFGFG+R C
Sbjct: 220 DIK------GSGRNFYHVPFGFGMRQC 240
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ T+ L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V + +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQIDHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 63.7 bits (148), Expect = 8e-10
Identities = 50/149 (33%), Positives = 68/149 (45%), Gaps = 11/149 (7%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRAC 540
+EML G+DT S L+ +A N KVQD LR E+ + + +A
Sbjct: 321 TEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKAS 380
Query: 539 LKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE LRL H + L+R D ++ Y IP V L R F+ PE F P R
Sbjct: 381 IKETLRL-HPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTR 439
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
WL + + Y+ N L FG+GVR C
Sbjct: 440 WLSKDKNITYFRN------LGFGWGVRQC 462
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 63.7 bits (148), Expect = 8e-10
Identities = 50/149 (33%), Positives = 68/149 (45%), Gaps = 11/149 (7%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRAC 540
+EML G+DT S L+ +A N KVQD LR E+ + + +A
Sbjct: 39 TEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKAS 98
Query: 539 LKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE LRL H + L+R D ++ Y IP V L R F+ PE F P R
Sbjct: 99 IKETLRL-HPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTR 157
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
WL + + Y+ N L FG+GVR C
Sbjct: 158 WLSKDKNITYFRN------LGFGWGVRQC 180
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 63.7 bits (148), Expect = 8e-10
Identities = 50/149 (33%), Positives = 68/149 (45%), Gaps = 11/149 (7%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRAC 540
+EML G+DT S L+ +A N KVQD LR E+ + + +A
Sbjct: 321 TEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKAS 380
Query: 539 LKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE LRL H + L+R D ++ Y IP V L R F+ PE F P R
Sbjct: 381 IKETLRL-HPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTR 439
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
WL + + Y+ N L FG+GVR C
Sbjct: 440 WLSKDKNITYFRN------LGFGWGVRQC 462
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 63.7 bits (148), Expect = 8e-10
Identities = 50/149 (33%), Positives = 68/149 (45%), Gaps = 11/149 (7%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRAC 540
+EML G+DT S L+ +A N KVQD LR E+ + + +A
Sbjct: 321 TEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKAS 380
Query: 539 LKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE LRL H + L+R D ++ Y IP V L R F+ PE F P R
Sbjct: 381 IKETLRL-HPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTR 439
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
WL + + Y+ N L FG+GVR C
Sbjct: 440 WLSKDKNITYFRN------LGFGWGVRQC 462
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R +VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSLVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/159 (29%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI +N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 10 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 68
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 69 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 128
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 129 NPSEFLPERFL 139
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 179 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 238
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 239 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 298
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 299 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 332
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 276 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 334
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 335 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 394
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 395 NPSEFLPERFL 405
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 43 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 101
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 102 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 161
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 162 NPSEFLPERFL 172
>AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1
protein.
Length = 175
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 43 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 101
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 102 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 161
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 162 NPSEFLPERFL 172
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 304 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 362
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 363 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 422
Query: 389 RPE*FIPERWL 357
P F+PER+L
Sbjct: 423 NPSEFLPERFL 433
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PER+ + D + +PFG G R+C
Sbjct: 409 TEPEKFCPERFSKKNKDSIDLYR-----YIPFGAGPRNC 442
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/145 (31%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKE 531
+ AG +T S V + L+ LA + VQ KL++EI N Y + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG V+ P L K++ PE F PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
K + P + PFG G R+C
Sbjct: 423 KD------SIDPYIYTPFGTGPRNC 441
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/145 (31%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKE 531
+ AG +T S V + L+ LA + VQ KL++EI N Y + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG V+ P L K++ PE F PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
K + P + PFG G R+C
Sbjct: 423 KD------SIDPYIYTPFGTGPRNC 441
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/145 (31%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKE 531
+ AG +T S V + L+ LA + VQ KL++EI N Y + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG V+ P L K++ PE F PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
K + P + PFG G R+C
Sbjct: 423 KD------SIDPYIYTPFGTGPRNC 441
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/146 (31%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYK-RYFRACLK 534
+ G DT + L+ L N +VQ K+ E+ T E K RY +K
Sbjct: 327 MFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIK 386
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E LRL VP R D V GY + KG + + L R +++P PE F PER+
Sbjct: 387 ETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFP 446
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 447 ENAQ-----GRHPYAYVPFSAGPRNC 467
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/146 (31%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYK-RYFRACLK 534
+ G DT + L+ L N +VQ K+ E+ T E K RY +K
Sbjct: 327 MFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIK 386
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E LRL VP R D V GY + KG + + L R +++P PE F PER+
Sbjct: 387 ETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFP 446
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 447 ENAQ-----GRHPYAYVPFSAGPRNC 467
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/145 (31%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKE 531
+ AG +T S V + L+ LA + VQ KL++EI N Y + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 530 ALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVE 351
LRL V R +D + G +IPKG V+ P L K++ PE F PER+ +
Sbjct: 363 TLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKK 422
Query: 350 KSDPLYYGNAHPLVTLPFGFGVRSC 276
K + P + PFG G R+C
Sbjct: 423 KD------SIDPYIYTPFGTGPRNC 441
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/146 (31%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYK-RYFRACLK 534
+ G DT + L+ L N +VQ K+ E+ T E K RY +K
Sbjct: 305 MFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIK 364
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E LRL VP R D V GY + KG + + L R +++P PE F PER+
Sbjct: 365 ETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFP 424
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 425 ENAQ-----GRHPYAYVPFSAGPRNC 445
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/146 (31%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYK-RYFRACLK 534
+ G DT + L+ L N +VQ K+ E+ T E K RY +K
Sbjct: 327 MFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIK 386
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E LRL VP R D V GY + KG + + L R +++P PE F PER+
Sbjct: 387 ETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFP 446
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 447 ENAQ-----GRHPYAYVPFSAGPRNC 467
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 12/145 (8%)
Frame = -1
Query: 674 AGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEAL 525
AG++T + V L L N +V+ KL EEI RT S+ N A ++E L
Sbjct: 302 AGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVL 361
Query: 524 RLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLVEK 348
RLR V P + + + D +G + + KG +VI L +EK + +P+ F+PER+L
Sbjct: 362 RLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL--- 418
Query: 347 SDPLYYGNAHPLVT-LPFGFGVRSC 276
+P P V+ LPFG G RSC
Sbjct: 419 -NPAGTQLISPSVSYLPFGAGPRSC 442
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 311 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 370
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 371 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 430
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 431 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 483
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 484 PLTFPNHFILKPKNGMYLHLK 504
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 311 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 370
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 371 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 430
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 431 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 483
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 484 PLTFPNHFILKPKNGMYLHLK 504
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 311 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 370
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 371 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 430
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 431 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 483
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 484 PLTFPNHFILKPKNGMYLHLK 504
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 311 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 370
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 371 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 430
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 431 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 483
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 484 PLTFPNHFILKPKNGMYLHLK 504
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 310 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 369
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 370 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 429
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 430 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 482
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 483 PLTFPNHFILKPKNGMYLHLK 503
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 311 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 370
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 371 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 430
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 431 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 483
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 484 PLTFPNHFILKPKNGMYLHLK 504
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 11/201 (5%)
Frame = -1
Query: 689 SEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRAC 540
S LLAG DT++ + +L+ LA+N + Q++ REE+R + Y C
Sbjct: 246 STFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMC 305
Query: 539 LKEALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPER 363
+KE RL VP+ R + G +P GI V+ L + + P+ F P R
Sbjct: 306 IKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR 365
Query: 362 WLVEKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKVTWNGPPIK 183
+ E SD HP LPF G R+C F+VT P +
Sbjct: 366 FSQENSD-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTR 418
Query: 182 IVNKLTNTFVKPYNFTFISVK 120
+ + +KP N ++ +K
Sbjct: 419 PLTFPNHFILKPKNGMYLHLK 439
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 58.4 bits (135), Expect = 3e-08
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + F+ P
Sbjct: 472 QKIHDLFLHP 481
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 11/153 (7%)
Frame = -1
Query: 701 VMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRY 552
+ E+++AG +T + V + +A+ +Q ++++EI + Y
Sbjct: 301 IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPY 360
Query: 551 FRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
A L E LR ++VP + T D +V GY IPKG VI + EK++ PE F
Sbjct: 361 TEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVF 420
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PER+L Y+ LV PF G R C
Sbjct: 421 HPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 11/153 (7%)
Frame = -1
Query: 701 VMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRY 552
+ E+++AG +T + V + +A+ +Q ++++EI + Y
Sbjct: 301 IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPY 360
Query: 551 FRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
A L E LR ++VP + T D +V GY IPKG VI + EK++ PE F
Sbjct: 361 TEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVF 420
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PER+L Y+ LV PF G R C
Sbjct: 421 HPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 11/153 (7%)
Frame = -1
Query: 701 VMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRY 552
+ E+++AG +T + V + +A+ +Q ++++EI + Y
Sbjct: 301 IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPY 360
Query: 551 FRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
A L E LR ++VP + T D +V GY IPKG VI + EK++ PE F
Sbjct: 361 TEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVF 420
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PER+L Y+ LV PF G R C
Sbjct: 421 HPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 58.4 bits (135), Expect = 3e-08
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PE +K+ + +PFG G R+C
Sbjct: 409 TEPEKFCPESRFSKKNK----DSIDLYRYIPFGAGPRNC 443
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 58.4 bits (135), Expect = 3e-08
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PE F PE +K+ + +PFG G R+C
Sbjct: 409 TEPEKFCPESRFSKKNK----DSIDLYRYIPFGAGPRNC 443
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 12/161 (7%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TS 573
+ DE+ + ++ +AG DT + L +++N VQ+K+ EEI +
Sbjct: 336 SFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLT 395
Query: 572 ESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEY-LSRSEK 399
+ Y A + E RL VVP + T + ++ GY IPKG +I PN + + R
Sbjct: 396 DKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKG-TLILPNLWSVHRDPA 454
Query: 398 FYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ +PE F P R+L ++ + +PFG G R C
Sbjct: 455 IWEKPEDFYPNRFLDDQGQLI-----KKETFIPFGIGKRVC 490
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 10/130 (7%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 149 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 208
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 209 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 268
Query: 392 PRPE*FIPER 363
PE F PER
Sbjct: 269 TEPEKFCPER 278
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 12/161 (7%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIR----------TS 573
+ DE+ + ++ +AG DT + L +++N VQ+K+ EEI +
Sbjct: 336 SFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLT 395
Query: 572 ESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEY-LSRSEK 399
+ Y A + E RL VVP + T + ++ GY IPKG +I PN + + R
Sbjct: 396 DKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKG-TLILPNLWSVHRDPA 454
Query: 398 FYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ +PE F P R+L ++ + +PFG G R C
Sbjct: 455 IWEKPEDFYPNRFLDDQGQLI-----KKETFIPFGIGKRVC 490
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 10/130 (7%)
Frame = -1
Query: 722 AIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN------- 564
A+ + V + ++ A DT S +++ LA + VQ KL+EEI N
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 563 ---YKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y + E LRL VV R +D + G +IPKG+ V+ P L K++
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
Query: 392 PRPE*FIPER 363
PE F PER
Sbjct: 409 TEPEKFCPER 418
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 55.6 bits (128), Expect = 2e-07
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 10/103 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGI 441
Y +ACLKE++RL VP R + ++G Y +PKGI
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGI 413
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 55.6 bits (128), Expect = 2e-07
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 10/103 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGI 441
Y +ACLKE++RL VP R + ++G Y +PKGI
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGI 413
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 55.6 bits (128), Expect = 2e-07
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 10/103 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR--- 555
+ +K +E+ LA ++T + +L+NL+ N +VQ KL +EI++ E+ R
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 554 -----YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGI 441
Y +ACLKE++RL VP R + ++G Y +PKGI
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGI 413
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 218 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 277
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 278 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 334
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 335 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 387
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 388 QKIHDLSLHP 397
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 218 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 277
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 278 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 334
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 335 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 387
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 388 QKIHDLSLHP 397
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 10/190 (5%)
Frame = -1
Query: 686 EMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLK 534
EML+A DT+S +LF +A + V++ + +EI+T E + K + +
Sbjct: 302 EMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIY 361
Query: 533 EALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
E++R + VV +R+ D ++ GY + KG ++I + R E F+P+P F E +
Sbjct: 362 ESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF-- 418
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXEFKV-TWNGPPIKIV 177
K+ P Y PFGFG R C F V T G ++ +
Sbjct: 419 AKNVPYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESI 471
Query: 176 NKLTNTFVKP 147
K+ + + P
Sbjct: 472 QKIHDLSLHP 481
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 15/163 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYK-- 558
+D + ++E+L G +T + TSL+ L + V K+REE+++ +SN
Sbjct: 216 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 275
Query: 557 ---------RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRS 405
+Y +KE LRL VP R + + GY IPKG +VI
Sbjct: 276 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 335
Query: 404 EKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ + E F P+R+++ + +A +PFG G+RSC
Sbjct: 336 AEIFTNKEEFNPDRFMLPHPE-----DASRFSFIPFGGGLRSC 373
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 15/163 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYK-- 558
+D + ++E+L G +T + TSL+ L + V K+REE+++ +SN
Sbjct: 285 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 344
Query: 557 ---------RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRS 405
+Y +KE LRL VP R + + GY IPKG +VI
Sbjct: 345 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 404
Query: 404 EKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ + E F P+R+++ + +A +PFG G+RSC
Sbjct: 405 AEIFTNKEEFNPDRFMLPHPE-----DASRFSFIPFGGGLRSC 442
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 15/163 (9%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTS----ESNYK-- 558
+D + ++E+L G +T + TSL+ L + V K+REE+++ +SN
Sbjct: 285 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 344
Query: 557 ---------RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRS 405
+Y +KE LRL VP R + + GY IPKG +VI
Sbjct: 345 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 404
Query: 404 EKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ + E F P+R+++ + +A +PFG G+RSC
Sbjct: 405 AEIFTNKEEFNPDRFMLPHPE-----DASRFSFIPFGGGLRSC 442
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 54.0 bits (124), Expect = 7e-07
Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL +L + Q++Q++L E+ S+ YK R
Sbjct: 19 MAAVDLLIGGTETTANTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYKDRARL 78
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 79 PLLIATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 138
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 139 EFWPDRFL 146
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/128 (32%), Positives = 65/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK + R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/161 (29%), Positives = 70/161 (43%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A ++E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1
protein.
Length = 144
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 11/122 (9%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 23 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 81
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
++ Y A + E R VP + T RD + G+YIPKG V ++ +K +
Sbjct: 82 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWV 141
Query: 389 RP 384
P
Sbjct: 142 NP 143
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 16/145 (11%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWLV--EKSDPLYYGNAHPL 312
F P+R+L + S L +G P+
Sbjct: 403 EFWPDRFLEPGKNSRALAFGCGAPV 427
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 253 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 312
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 313 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 372
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 373 EFWPDRFL 380
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGID----TVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G + T+S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTENTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 254 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 313
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 314 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 373
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 374 EFWPDRFL 381
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 254 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 313
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 314 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 373
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 374 EFWPDRFL 381
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 254 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 313
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 314 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 373
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 374 EFWPDRFL 381
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 254 MAAVDLLIGGTETTANTLSWAAVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 313
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 314 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 373
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 374 EFWPDRFL 381
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 274 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 331
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 332 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 391
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 392 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 432
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 243 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 300
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 301 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 360
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 361 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 401
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 192 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 251
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 252 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 311
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 312 EFWPDRFL 319
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 51.2 bits (117), Expect = 5e-06
Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 284 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 343
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 344 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 403
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 404 EFWPDRFL 411
>AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 variant protein.
Length = 336
Score = 51.2 bits (117), Expect = 5e-06
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-- 582
E+E E+L +D + V +A ++ AG +T S L L ++++KL EEI
Sbjct: 170 EKEKHSAERLYTMDG-ITVTVA-DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDR 227
Query: 581 --------RTSESNYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIA 429
+ Y A + E R +VP+NL RD I GY IPKG V+
Sbjct: 228 VIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVP 287
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVT 306
+ + + +P PE F PE +L E Y P T
Sbjct: 288 TLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST 328
>AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein.
Length = 522
Score = 46.0 bits (104), Expect(2) = 5e-06
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Frame = -1
Query: 557 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY-PRPE 381
RY +KE LRL V R R + GY IPKG V+ + Y PE
Sbjct: 367 RYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPE 426
Query: 380 *FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PER+ + D G + L +PFG G RSC
Sbjct: 427 GFDPERFGAAREDS--RGASSRLHYIPFGGGARSC 459
Score = 24.6 bits (51), Expect(2) = 5e-06
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI 582
A E+L A T + +TSL+ L + K+REE+
Sbjct: 290 AVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREEL 326
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 50.8 bits (116), Expect = 6e-06
Identities = 40/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + V + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LR+ VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 50.0 bits (114), Expect = 1e-05
Identities = 31/93 (33%), Positives = 43/93 (46%)
Frame = -1
Query: 554 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
Y + E LRL V R +D + G +IPKG V+ P L K++ PE F
Sbjct: 26 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 85
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PER+ +K + P + PFG G R+C
Sbjct: 86 RPERFSKKKD------SIDPYIYTPFGTGPRNC 112
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 50.0 bits (114), Expect = 1e-05
Identities = 31/93 (33%), Positives = 43/93 (46%)
Frame = -1
Query: 554 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
Y + E LRL V R +D + G +IPKG V+ P L K++ PE F
Sbjct: 13 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 72
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
PER+ +K + P + PFG G R+C
Sbjct: 73 RPERFSKKKD------SIDPYIYTPFGTGPRNC 99
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ L + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L RT R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family
26, subfamily C, polypeptide 1 protein.
Length = 522
Score = 44.4 bits (100), Expect(2) = 1e-05
Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Frame = -1
Query: 557 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY-PRPE 381
RY +KE LRL V R R + GY IPKG V+ + Y PE
Sbjct: 367 RYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPE 426
Query: 380 *FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
F PER+ + D G + +PFG G RSC
Sbjct: 427 GFDPERFGAAREDS--RGASSRFHYIPFGGGARSC 459
Score = 24.6 bits (51), Expect(2) = 1e-05
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI 582
A E+L A T + +TSL+ L + K+REE+
Sbjct: 290 AVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREEL 326
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT------------SESNYKRYF 549
A + G DT + + +L++LA + + Q++ R+E++ + + +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VP R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L++LA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VPA R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L++LA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VPA R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L++LA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VPA R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L++LA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VPA R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L++LA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL VPA R +D ++ G IPKGI + + +P PE +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + Y C+KE
Sbjct: 3 MFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKE 62
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 63 ALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAP 122
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 123 GSAQ-------HSHAFLPFSGGSRNC 141
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1
protein.
Length = 157
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 11/102 (10%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSES 567
DEK+ + + ++ AG DTV+ + L L MN +VQ K++EE+ R S+
Sbjct: 43 DEKI-INIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR 101
Query: 566 NYKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKG 444
++ Y A + E R VP + T RD + G+YIPKG
Sbjct: 102 SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKG 143
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 14/128 (10%)
Frame = -1
Query: 698 MMASEMLLAGIDT----VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR- 546
M A ++L+ G +T +S+ LL + + Q++Q++L E+ S+ YK R
Sbjct: 283 MAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARL 342
Query: 545 ----ACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE 381
A + E LRLR VVP L T R + GY IP+G +I + E + RP
Sbjct: 343 PLLNATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPH 402
Query: 380 *FIPERWL 357
F P+R+L
Sbjct: 403 EFWPDRFL 410
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 243 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 302
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 303 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 362
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 363 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 393
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 409 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 256 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 315
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 316 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 375
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 376 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 402
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FI 372
C+KE+LRL P R +D ++ G IPKGI + + + +P PE +
Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYD 441
Query: 371 PERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP PL +PF G R+C
Sbjct: 442 PFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 47.6 bits (108), Expect = 6e-05
Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT-----SESNYKR-----YFRACLKE 531
+ AG DT S + +L+ LA + Q + R+EIR S ++ Y C+KE
Sbjct: 312 MFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKE 371
Query: 530 ALRLRHVVPANLRRTHRDHIV--GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
LRL V N+ R I G +P GI V L + F+ P+ F P R+
Sbjct: 372 CLRLYAPV-VNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFS 430
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E S+ + HP +PF G+R+C
Sbjct: 431 RENSEKI-----HPYAFIPFSAGLRNC 452
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 47.6 bits (108), Expect = 6e-05
Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT-----SESNYKR-----YFRACLKE 531
+ AG DT S + +L+ LA + Q + R+EIR S ++ Y C+KE
Sbjct: 312 MFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKE 371
Query: 530 ALRLRHVVPANLRRTHRDHIV--GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
LRL V N+ R I G +P GI V L + F+ P+ F P R+
Sbjct: 372 CLRLYAPV-VNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFS 430
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E S+ + HP +PF G+R+C
Sbjct: 431 RENSEKI-----HPYAFIPFSAGLRNC 452
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 47.6 bits (108), Expect = 6e-05
Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT-----SESNYKR-----YFRACLKE 531
+ AG DT S + +L+ LA + Q + R+EIR S ++ Y C+KE
Sbjct: 312 MFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKE 371
Query: 530 ALRLRHVVPANLRRTHRDHIV--GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
LRL V N+ R I G +P GI V L + F+ P+ F P R+
Sbjct: 372 CLRLYAPV-VNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFS 430
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E S+ + HP +PF G+R+C
Sbjct: 431 RENSEKI-----HPYAFIPFSAGLRNC 452
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 47.6 bits (108), Expect = 6e-05
Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT-----SESNYKR-----YFRACLKE 531
+ AG DT S + +L+ LA + Q + R+EIR S ++ Y C+KE
Sbjct: 312 MFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKE 371
Query: 530 ALRLRHVVPANLRRTHRDHIV--GGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWL 357
LRL V N+ R I G +P GI V L + F+ P+ F P R+
Sbjct: 372 CLRLYAPV-VNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFS 430
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E S+ + HP +PF G+R+C
Sbjct: 431 RENSEKI-----HPYAFIPFSAGLRNC 452
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 47.6 bits (108), Expect = 6e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDVFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 320 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 379
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 380 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 439
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 440 GSAQ-------HSHAFLPFSGGSRNC 458
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 47.2 bits (107), Expect = 8e-05
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 302 IPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 361
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 362 RPQLPYLEAFILETFRHSPFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 421
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ FG G R C
Sbjct: 422 EDPSEFRPERFLTADGTAINKPLSEKMML--FGMGKRRC 458
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 47.2 bits (107), Expect = 8e-05
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNY 561
K +M + +AG +TVS L + +V+ K+ EEI + +
Sbjct: 289 KNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTK 348
Query: 560 KRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L +K + + V PF G R C
Sbjct: 409 QDFNPQHFLDDKGQ---FKKSDAFV--PFSIGKRYC 439
>M12078-1|AAA52154.1| 192|Homo sapiens POR protein.
Length = 192
Score = 46.8 bits (106), Expect = 1e-04
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Frame = -1
Query: 719 IDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----- 555
I ++ V + +++ AG DTV+ + L L ++Q K+++E+ T +R
Sbjct: 8 IPQEKIVNLLNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD 67
Query: 554 -----YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFY 393
Y A + E R +P + T RD + G+YIPK V ++ + +
Sbjct: 68 RPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW 127
Query: 392 PRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P F PER+L + + ++ L G G R C
Sbjct: 128 EDPSEFRPERFLTADGTAINKPLSEKMMML-VGMGKRRC 165
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 46.8 bits (106), Expect = 1e-04
Identities = 44/146 (30%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + +L+ LA + K Q++ REEI + + + Y C+KE
Sbjct: 319 MFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKE 378
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*FIPERWLV 354
ALRL VP R G +PKGI V+ L + K +P PE F P R+
Sbjct: 379 ALRLFPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP 438
Query: 353 EKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ H LPF G R+C
Sbjct: 439 GSAQ-------HSHAFLPFSGGSRNC 457
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K VM + + G +TVS L + +V+ ++ EEI R N +
Sbjct: 284 KNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNRQPKFEDRAK 343
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 344 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 403
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L EK + + V PF G R+C
Sbjct: 404 QDFNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 434
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 11/132 (8%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-----RTSESNYKR--- 555
K +M + +AG +TVS L + +V+ K+ EEI + + ++
Sbjct: 289 KNLMMSTLNLFIAGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 554 --YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKGI+V + R +F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGSVLRDLRFFSNP 408
Query: 383 E*FIPERWLVEK 348
F P+ +L EK
Sbjct: 409 RDFNPQHFLGEK 420
>EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 216
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 11/126 (8%)
Frame = -1
Query: 701 VMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRY 552
+M +L G TVS L KVQ +++EEI + Y
Sbjct: 74 LMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPY 133
Query: 551 FRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRPE*F 375
A + E R ++P NL R RD G+ IPKG DVI P + + P+ F
Sbjct: 134 TDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITPLNTVHYDPSQFLTPQEF 193
Query: 374 IPERWL 357
PE +L
Sbjct: 194 NPEHFL 199
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI-RTSESNYK-------- 558
K +M + +AG +TVS L + +V+ K+ EEI R N +
Sbjct: 289 KNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAK 348
Query: 557 -RYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNP 408
Query: 383 E*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+ F P+ +L +K + + V PF G R C
Sbjct: 409 QDFNPQHFLDDKGQ---FKKSDAFV--PFSIGKRYC 439
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Frame = -1
Query: 713 EKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESN 564
E+ + ++ AG +T S L +A+ ++Q+K++ EI T+
Sbjct: 298 EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE 357
Query: 563 YKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPR 387
Y A + E R+ +++P N+ R D + GY++PKG ++ L R +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 386 PE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P+ F P+ +L ++ A +PF G R+C
Sbjct: 418 PDTFNPDHFL--ENGQFKKREAF----MPFSIGKRAC 448
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Frame = -1
Query: 713 EKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESN 564
E+ + ++ AG +T S L +A+ ++Q+K++ EI T+
Sbjct: 298 EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE 357
Query: 563 YKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPR 387
Y A + E R+ +++P N+ R D + GY++PKG ++ L R +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 386 PE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P+ F P+ +L ++ A +PF G R+C
Sbjct: 418 PDTFNPDHFL--ENGQFKKREAF----MPFSIGKRAC 448
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Frame = -1
Query: 713 EKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESN 564
E+ + ++ AG +T S L +A+ ++Q+K++ EI T+
Sbjct: 298 EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE 357
Query: 563 YKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPR 387
Y A + E R+ +++P N+ R D + GY++PKG ++ L R +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 386 PE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P+ F P+ +L ++ A +PF G R+C
Sbjct: 418 PDTFNPDHFL--ENGQFKKREAF----MPFSIGKRAC 448
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Frame = -1
Query: 713 EKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESN 564
E+ + ++ AG +T S L +A+ ++Q+K++ EI T+
Sbjct: 298 EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE 357
Query: 563 YKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPR 387
Y A + E R+ +++P N+ R D + GY++PKG ++ L R +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 386 PE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P+ F P+ +L ++ A +PF G R+C
Sbjct: 418 PDTFNPDHFL--ENGQFKKREAF----MPFSIGKRAC 448
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 11/132 (8%)
Frame = -1
Query: 710 KVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNY 561
K +M + +AG +TVS L + +V+ K+ EEI + +
Sbjct: 289 KNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTK 348
Query: 560 KRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPRP 384
Y A + E R V+P +L RR +D +++PKG +V + R +F+ P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDLRFFSNP 408
Query: 383 E*FIPERWLVEK 348
F P+ +L EK
Sbjct: 409 RDFNPQHFLGEK 420
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 14/153 (9%)
Frame = -1
Query: 692 ASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT--SESNYKR----------YF 549
A + G DT + + +L+NLA + + Q++ R+E++ + K +
Sbjct: 322 ADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 548 RACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKGIDVIAPNEY-LSRSEKFYPRPE*F 375
CLKE+LRL +P R +D ++ IPKG +V N + + + +P PE +
Sbjct: 382 TMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKG-NVCNINIFAIHHNPSVWPDPEVY 440
Query: 374 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P R+ DP P+ +PF G R+C
Sbjct: 441 DPFRF-----DPENAQKRSPMAFIPFSAGPRNC 468
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 45.2 bits (102), Expect = 3e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Frame = -1
Query: 713 EKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESN 564
E+ + ++ AG +T S L +A+ ++Q+K++ EI T+
Sbjct: 298 EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPSTAARE 357
Query: 563 YKRYFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPR 387
Y A + E R+ +++P N+ R D + GY++PKG ++ L R +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 386 PE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
P+ F P+ +L ++ A +PF G R+C
Sbjct: 418 PDTFNPDHFL--ENGQFKKREAF----MPFSIGKRAC 448
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 44.0 bits (99), Expect = 7e-04
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + L+ +A+ + Q + REE+R + Y C+KE
Sbjct: 313 MFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKE 372
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPRPE*FIPERWL 357
+ RL VP R+ + V G +P G +I+ + Y L R+ +P PE F R+
Sbjct: 373 SFRLYPPVPQVYRQLSKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFS 431
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 432 TENAS-----KRHPFAFMPFSAGPRNC 453
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLRIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/171 (27%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT 576
+ + S + + + +DE V A L+AG + ++ + + LA N Q+KL E+
Sbjct: 317 QHQPSPMARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDV 374
Query: 575 SESNYKRYFRACLKEAL---------RLRHVVPAN--LRRTHRDHIVGGYYIPKGIDVIA 429
+ + L+E L LR PA R +D V G IP G +
Sbjct: 375 FKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEM 434
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L + +P PE F PER+ E P LPFG G RSC
Sbjct: 435 AVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSC 480
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLRIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 44.0 bits (99), Expect = 7e-04
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + L+ +A+ + Q + REE+R + Y C+KE
Sbjct: 313 MFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKE 372
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPRPE*FIPERWL 357
+ RL VP R+ + V G +P G +I+ + Y L R+ +P PE F R+
Sbjct: 373 SFRLYPPVPQVYRQLSKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFS 431
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 432 TENAS-----KRHPFAFMPFSAGPRNC 453
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/171 (27%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Frame = -1
Query: 755 EEEXSVLEKLIAIDEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT 576
+ + S + + + +DE V A L+AG + ++ + + LA N Q+KL E+
Sbjct: 316 QHQPSPMARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDV 373
Query: 575 SESNYKRYFRACLKEAL---------RLRHVVPAN--LRRTHRDHIVGGYYIPKGIDVIA 429
+ + L+E L LR PA R +D V G IP G +
Sbjct: 374 FKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEM 433
Query: 428 PNEYLSRSEKFYPRPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
L + +P PE F PER+ E P LPFG G RSC
Sbjct: 434 AVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSC 479
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 44.0 bits (99), Expect = 7e-04
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Frame = -1
Query: 680 LLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKE 531
+ G DT + + L+ +A+ + Q + REE+R + Y C+KE
Sbjct: 313 MFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKE 372
Query: 530 ALRLRHVVPANLRRTHRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPRPE*FIPERWL 357
+ RL VP R+ + V G +P G +I+ + Y L R+ +P PE F R+
Sbjct: 373 SFRLYPPVPQVYRQLSKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFS 431
Query: 356 VEKSDPLYYGNAHPLVTLPFGFGVRSC 276
E + HP +PF G R+C
Sbjct: 432 TENAS-----KRHPFAFMPFSAGPRNC 453
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 295 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 353
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 354 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 413
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 414 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 446
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 11/158 (6%)
Frame = -1
Query: 716 DEKVAVMMASEMLLAGIDTVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR------ 555
DE + +++A ++ AG+ T S L + ++ VQ ++++EI +R
Sbjct: 292 DENLCIVVA-DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 554 ----YFRACLKEALRLRHVVPANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYP 390
Y A + E R +VP + T RD V G+ IPKG +I + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 389 RPE*FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 276
+P F PE +L + P LPF G R+C
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRAC 443
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,851,568
Number of Sequences: 237096
Number of extensions: 2168550
Number of successful extensions: 4331
Number of sequences better than 10.0: 402
Number of HSP's better than 10.0 without gapping: 3956
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4079
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10872716010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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