Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_pT_B12
(852 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 378 e-103
UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 283 4e-75
UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 281 1e-74
UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 260 3e-68
UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 254 3e-66
UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 243 5e-63
UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 232 7e-60
UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 224 2e-57
UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 200 5e-50
UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 187 3e-46
UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 179 7e-44
UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 179 7e-44
UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 174 3e-42
UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 161 2e-38
UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 160 5e-38
UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 159 1e-37
UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 155 2e-36
UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 154 2e-36
UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 151 2e-35
UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 149 1e-34
UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 148 2e-34
UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 146 8e-34
UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 142 8e-33
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 142 1e-32
UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 142 1e-32
UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 141 2e-32
UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 139 7e-32
UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 137 3e-31
UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 136 5e-31
UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 136 5e-31
UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 135 1e-30
UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 135 1e-30
UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 135 1e-30
UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 134 3e-30
UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 134 4e-30
UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 134 4e-30
UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 132 1e-29
UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 129 1e-28
UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 128 2e-28
UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 128 2e-28
UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 128 2e-28
UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 93 3e-28
UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 127 4e-28
UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 126 5e-28
UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 126 9e-28
UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 125 1e-27
UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 124 4e-27
UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 123 5e-27
UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 123 5e-27
UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 123 7e-27
UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 120 5e-26
UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 120 5e-26
UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 120 6e-26
UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 120 6e-26
UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 119 8e-26
UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 119 1e-25
UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 119 1e-25
UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 118 2e-25
UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 117 3e-25
UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 116 6e-25
UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 116 6e-25
UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 116 6e-25
UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 116 6e-25
UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 115 1e-24
UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 115 2e-24
UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 113 7e-24
UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 113 7e-24
UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 112 1e-23
UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 111 2e-23
UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 111 2e-23
UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 109 9e-23
UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 109 9e-23
UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 109 1e-22
UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 108 2e-22
UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 107 4e-22
UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 107 4e-22
UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 105 1e-21
UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 103 4e-21
UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 103 6e-21
UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 102 1e-20
UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 102 1e-20
UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 99 7e-20
UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 100 9e-20
UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 99 1e-19
UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 98 3e-19
UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 97 7e-19
UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 96 1e-18
UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 96 1e-18
UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 95 2e-18
UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 94 3e-18
UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 94 5e-18
UniRef50_Q9BZ93 Cluster: Prosomal P27K protein; n=6; Eutheria|Re... 93 8e-18
UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 93 1e-17
UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 91 2e-17
UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 91 3e-17
UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 90 6e-17
UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 84 5e-15
UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 83 7e-15
UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1; ... 83 9e-15
UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 82 2e-14
UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 80 8e-14
UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 79 1e-13
UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 76 1e-12
UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 75 2e-12
UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 75 2e-12
UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 73 7e-12
UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1... 73 9e-12
UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 68 3e-10
UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia... 65 2e-09
UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 64 4e-09
UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 64 4e-09
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 64 6e-09
UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1; ... 62 2e-08
UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1; ... 56 1e-06
UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 55 3e-06
UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 52 1e-05
UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 52 2e-05
UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 52 2e-05
UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04
UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia t... 46 0.001
UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 45 0.002
UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2; Olig... 44 0.004
UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1; Spra... 44 0.004
UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 44 0.005
UniRef50_Q9U794 Cluster: Proteasome subunit beta type-1; n=7; Tr... 42 0.015
UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar... 41 0.034
UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giar... 39 0.18
UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 39 0.18
UniRef50_Q980L4 Cluster: Proteasome subunit; n=4; Sulfolobaceae|... 38 0.32
UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9; ... 36 0.98
UniRef50_Q8LIW5 Cluster: P0497A05.6 protein; n=6; Magnoliophyta|... 36 1.3
UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella ch... 35 2.3
UniRef50_Q0FG88 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole gen... 35 2.3
UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;... 35 2.3
UniRef50_UPI0000DB72B7 Cluster: PREDICTED: similar to CG3558-PA,... 35 3.0
UniRef50_A2WY43 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0
UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1; Tric... 35 3.0
UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_Q6FB05 Cluster: Maf-like protein ACIAD1930; n=2; Acinet... 33 6.9
UniRef50_Q4Q7T3 Cluster: Zn finger protein, putative; n=3; Leish... 33 9.1
UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
UniRef50_A5AB88 Cluster: Contig An08c0230, complete genome. prec... 33 9.1
>UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69;
Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo
sapiens (Human)
Length = 246
Score = 378 bits (930), Expect = e-103
Identities = 173/242 (71%), Positives = 205/242 (84%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
SSAGFDRHITIFSPEGRLYQVEYA KAINQGGLTSVA+RG D AV+ Q+KVPD+LLD +
Sbjct: 5 SSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSS 64
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+VTHLF +T+ IGCVMTGM ADSRSQV RARYEAANW+YKYG EIPV +LC+RIADISQV
Sbjct: 65 TVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQV 124
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQNAEMRPLGC M+LI D+E GP VYK DP+GYYC +KA AAG K + ++LEKK+K
Sbjct: 125 YTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVK 184
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
K+ D + + ++ AI+CLS VLS+DFK SEIE+GVV+ +NPKFR+LTE EID HL A+AE
Sbjct: 185 KKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAE 244
Query: 47 KD 42
+D
Sbjct: 245 RD 246
>UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9;
Bilateria|Rep: Proteasome subunit alpha type-6 -
Caenorhabditis elegans
Length = 246
Score = 283 bits (694), Expect = 4e-75
Identities = 126/242 (52%), Positives = 181/242 (74%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
SSAGFDRHITIFSPEGR+YQVEYA KAIN LT+VA++G DAAV+A Q++VPD L+
Sbjct: 5 SSAGFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVAD 64
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+VT ++ ++ +GC GMI D++ Q+ RA+ EAA+W+YK G ++P +L +++AD++Q
Sbjct: 65 TVTSVYQISQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQY 124
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQNAEMR LGC+++ I+YDDE GP VY+ DP+GYY K V+ G K + ++LEKK+K
Sbjct: 125 YTQNAEMRSLGCALLFISYDDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEKKIK 184
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
K+S+L++ +AI+LAI L L +D +S ++E+ VV+KDN KF LT +++ HL IA
Sbjct: 185 KKSELTSTEAIELAIEALQTSLGIDVRSKDLEVVVVTKDNSKFTKLTSDQVEHHLNQIAN 244
Query: 47 KD 42
+D
Sbjct: 245 RD 246
>UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15;
Eukaryota|Rep: Proteasome subunit alpha type-6-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 281 bits (690), Expect = 1e-74
Identities = 133/242 (54%), Positives = 178/242 (73%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S AG+DRHITIFSPEGRL+QVEYA KA+ G+TS+ +RG D+ V Q+KVPD+LLD +
Sbjct: 5 SGAGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQS 64
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
SVTHLF +T IG V TG+ AD+RS V +AR +AA +++ YG E+PV IL + IAD SQV
Sbjct: 65 SVTHLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQV 124
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ+A MRPLG M++ D+E GP +YK DP+G++ +KA +AG K + +LEKK+K
Sbjct: 125 YTQHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMK 184
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
+ + D+ +Q AIS L VL DFK++EIE+GVV +NP+FR LT EI+ HLTAI+E
Sbjct: 185 ENPSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHLTAISE 244
Query: 47 KD 42
+D
Sbjct: 245 RD 246
>UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3;
Eukaryota|Rep: Proteasome subunit alpha type - Emiliania
huxleyi
Length = 264
Score = 260 bits (637), Expect = 3e-68
Identities = 132/253 (52%), Positives = 174/253 (68%), Gaps = 11/253 (4%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
SSAG+DRHITIFSPEGRLYQVEYA KAI GLTSV +RG D VV QRKVPD+L DP
Sbjct: 5 SSAGYDRHITIFSPEGRLYQVEYAFKAIKTSGLTSVGVRGADPCVVLTQRKVPDKLYDPE 64
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
SVT+++A+T IG VMTG++ D+R+ V + R EAA +++ G +IPV L +R AD +QV
Sbjct: 65 SVTNMYAITPNIGLVMTGIVPDARASVKKLREEAAKFKFNNGYDIPVSYLAKRAADTAQV 124
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAG---PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
YTQ+A MRPLG +M++I D E P +++ DP+GYY YKA +AGAK + N +LEK
Sbjct: 125 YTQHANMRPLGIAMIIIGIDVEGEKKVPQLFRCDPAGYYVGYKATSAGAKEQEANNFLEK 184
Query: 236 KLKKRS--------DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTET 81
+ K + LS DD +QLA++CL VL D K+++IE VV DN F L+
Sbjct: 185 RFKPPAGSNVAVDPKLSHDDTVQLALACLQNVLGADLKANDIEACVVRHDNLAFTRLSAD 244
Query: 80 EIDRHLTAIAEKD 42
E++ LTA+AE+D
Sbjct: 245 ELETQLTALAERD 257
>UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome
undetermined scaffold_17, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 245
Score = 254 bits (621), Expect = 3e-66
Identities = 117/244 (47%), Positives = 170/244 (69%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
SR S G + +IT+FSPEGRLYQVEYA KA+ GLTS+ ++GTD + +++VPD+L+D
Sbjct: 2 SRGSQGHEFYITLFSPEGRLYQVEYAFKAVKTSGLTSIGVKGTDTVCLITEKRVPDKLID 61
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
SVT+LF ++++IG + TG+ +D+R+ V R RYEA ++ K G PV +L +R+AD++
Sbjct: 62 EKSVTNLFNVSEKIGALTTGIPSDARALVTRMRYEAGEFRLKNGYYCPVDVLSKRMADLA 121
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
Q TQ +MR G +L YDDE GP +YK DPSG+Y YKA A+G K + YLEK+
Sbjct: 122 QTNTQYYQMRSYGVETILCQYDDELGPLLYKLDPSGHYSGYKATASGVKEQEAINYLEKQ 181
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+KK++DL+ D+ I LAI L V+S DFK ++IE+G+V+K + KF LT ++D +L I
Sbjct: 182 IKKKADLNYDETIMLAIQTLQNVISQDFKPTDIEVGIVTKQDKKFHKLTNEQVDHYLNLI 241
Query: 53 AEKD 42
A +D
Sbjct: 242 ANRD 245
>UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha1 -
Cryptosporidium parvum Iowa II
Length = 252
Score = 243 bits (594), Expect = 5e-63
Identities = 117/243 (48%), Positives = 163/243 (67%), Gaps = 6/243 (2%)
Frame = -2
Query: 752 DRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVP------DRLLDP 591
DRHITIFSPEG+LYQ+EY +A+ +T++A++G D + ++KVP D+LLDP
Sbjct: 10 DRHITIFSPEGKLYQIEYTFRAVKNSNITAIAIKGKDTVCIVCEKKVPNQQGQQDKLLDP 69
Query: 590 ASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQ 411
A VT L+ + IG VM G+ D RS + + R A + ++ G EIPV L +IAD++Q
Sbjct: 70 AYVTSLYKVRKHIGAVMLGLAPDCRSIISKCREIAGKFAFEKGVEIPVSYLSHKIADVNQ 129
Query: 410 VYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
+YTQ+A MR LG S M I+ DDE GP +YK DP+GY+ SY+A A G K +GN LEK +
Sbjct: 130 LYTQHASMRLLGASGMFISIDDEDGPSLYKIDPAGYFASYRACAVGTKEREGNNALEKII 189
Query: 230 KKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIA 51
K S ++ I +I CL +L VDFK+ +IE+GVV+KD P+FR+L+ EID +LT IA
Sbjct: 190 KNEPLNSCEEVISASIDCLKTLLGVDFKAEDIEVGVVTKDMPEFRLLSVEEIDNYLTNIA 249
Query: 50 EKD 42
E+D
Sbjct: 250 ERD 252
>UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Ustilago maydis (Smut fungus)
Length = 305
Score = 232 bits (568), Expect = 7e-60
Identities = 108/212 (50%), Positives = 150/212 (70%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S + +DR++TIFSP+GRLYQVEYA KAIN GLTS+A+RG D +VV Q+KVPD+L+D +
Sbjct: 2 SRSSYDRYLTIFSPDGRLYQVEYAFKAINTAGLTSIAVRGKDCSVVVGQKKVPDKLIDAS 61
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
SVT++F LT IGC+MTG +AD+R+QV RA+ EAA+++YKYG I +L +R+A+++QV
Sbjct: 62 SVTNIFNLTPEIGCIMTGRVADARAQVQRAKMEAADFKYKYGYAITPDLLAKRMANMNQV 121
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ A MRP G SM+L+ D E GP ++K DP+GYY ++A AAG K + +LEK+ K
Sbjct: 122 YTQRAAMRPYGVSMILVGIDAERGPQIFKIDPAGYYVGFRATAAGVKQTEATNFLEKQFK 181
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIE 132
K S +T DA + + D + E E
Sbjct: 182 KSSTTTTGDAASAVPEAPAGASATDAAALEAE 213
>UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 242
Score = 224 bits (548), Expect = 2e-57
Identities = 105/242 (43%), Positives = 163/242 (67%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
+ G+DR +TIFSPEGRLYQVEYALKA LT+V + +AA + Q+K+PDRL+DP+
Sbjct: 2 AGTGYDRQLTIFSPEGRLYQVEYALKATKCESLTTVGVCSDEAACIITQKKLPDRLVDPS 61
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+VTHL ++ +GC M+G+ AD + R++Y A+ +Q YG E+PV ++ ++ AD +Q+
Sbjct: 62 TVTHLHRISKHVGCCMSGIYADGKVIAQRSQYYASKFQLDYGYEMPVSLVAKKTADFAQM 121
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
TQ+A MRP G S M I +D+ +GP ++++DP+G +++ AAG K + LEKK K
Sbjct: 122 LTQHAYMRPFGVSSMFIGWDEVSGPQLWRSDPAGSVAAFRGCAAGEKEQEAFNNLEKK-K 180
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
+L+ D + A+ CL V S +FK+++IEI +V+KDN F +L++ EI+ +L +E
Sbjct: 181 ITKELTVDQVVCQALDCLQTVTSSEFKATDIEIAIVTKDNKLFHLLSQQEIEHYLVLASE 240
Query: 47 KD 42
KD
Sbjct: 241 KD 242
>UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3;
Piroplasmida|Rep: Proteasome subunit alpha type -
Theileria annulata
Length = 276
Score = 200 bits (487), Expect = 5e-50
Identities = 111/272 (40%), Positives = 163/272 (59%), Gaps = 30/272 (11%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVP------D 606
S +G+DRHITIFSPEG+L+Q+EYALKA+ LT +A++ A V AQ+K+P D
Sbjct: 5 SHSGYDRHITIFSPEGKLFQLEYALKAVKNCNLTGLAIKDDSAIAVVAQKKLPAQQGNQD 64
Query: 605 RLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRI 426
LLD +SVT L+ +TD I ++ G+ D S + +AR A ++ YKYG IP +LC++I
Sbjct: 65 VLLDTSSVTSLYHITDEIFALLVGLPGDCLSILYKARQVALDYSYKYGINIPASVLCQKI 124
Query: 425 ADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAY 246
+D++QVYTQ+A MR C+ ++++ + + GP +YK D SG++ YKA GAK +
Sbjct: 125 SDLNQVYTQHAYMRLHACTGLILSIEPDVGPKIYKFDSSGWFAGYKACGIGAKEQESENA 184
Query: 245 LEKKLKKRSDLSTDDAI-------------------QLAISCLSQVLSVD-----FKSSE 138
LEK LK+R +S DA+ ++ I L ++ +D +S
Sbjct: 185 LEKTLKRREAMSLQDAMKSNLHVNTEVHQLSQGQETKVTIEALRCMIDIDAFTKGLGASS 244
Query: 137 IEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 42
IE+ V SKDNP FR L+E EI+ +LT I E D
Sbjct: 245 IEVAVASKDNPFFRQLSEEEIETYLTHITESD 276
>UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 241
Score = 187 bits (456), Expect = 3e-46
Identities = 94/243 (38%), Positives = 154/243 (63%), Gaps = 2/243 (0%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
S+G DR++T+FS EGRL+QVEY+ KA+ Q +T+VA++ +A VA Q+KV D+L+DP++
Sbjct: 2 SSGADRYLTVFSAEGRLWQVEYSFKAVKQAEVTAVAVKSKNAVCVAVQKKVSDKLIDPST 61
Query: 584 VTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVY 405
VTH++ +TD +G + G+ +D V R A N++YK G IPV IL + +++ Q+
Sbjct: 62 VTHMYRITDNVGACLVGLPSDVNFIVMLLRSFANNFEYKQGFSIPVSILAQMLSERHQLE 121
Query: 404 TQNAEMRPLGCSMMLIAYDDEAGP-CVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
+Q +RP S +L D + +YK +PSGY ++AVA G K ++ + LEKK++
Sbjct: 122 SQLVYVRPSAVSAILFGLDGPSDSFALYKIEPSGYSNGFRAVACGVKEIEAMSALEKKME 181
Query: 227 KRSDLSTDDA-IQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIA 51
D T +A + +S L V VDF++ ++E+ ++++DN KF L +++ L A+A
Sbjct: 182 ---DFETPEATAEFTLSTLQTVCGVDFEAQDVEVSLLTRDNSKFSKLPNDKVNEILHAVA 238
Query: 50 EKD 42
EKD
Sbjct: 239 EKD 241
>UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza
sativa|Rep: Proteasome subunit alpha type - Oryza sativa
subsp. japonica (Rice)
Length = 253
Score = 179 bits (436), Expect = 7e-44
Identities = 94/227 (41%), Positives = 145/227 (63%), Gaps = 3/227 (1%)
Frame = -2
Query: 776 GSRSS--AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDR 603
GSR++ A ++R IT+FSPEGRL Q++YA A+ G+TSV +RG D+ V RK D+
Sbjct: 14 GSRAAGPADYERFITLFSPEGRLCQLDYAFNAVKLAGITSVGVRGDDSVYVLTHRK-EDK 72
Query: 602 LLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIA 423
L DP ++T+LFA+TDRIG + TGM D R+ AR AA +++K+G ++ +L + IA
Sbjct: 73 LHDPTTITNLFAITDRIGLLATGMPGDGRAIAQEARNAAAEFRFKWGYKMSPCMLAQWIA 132
Query: 422 DISQVYTQNAEMRPLGCSMMLIAYDDEAG-PCVYKTDPSGYYCSYKAVAAGAKTVDGNAY 246
D +Q+ TQ+A++RP G M+ D+E G P ++ DP+G + ++KA +AG K + +
Sbjct: 133 DRAQIRTQHAQIRPYGVVSMIFGIDEEKGTPELFTCDPAGQFFAHKATSAGPKEKEVMNF 192
Query: 245 LEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNP 105
LE+++K + LS+ LA S L VL DF + E E+G + K +P
Sbjct: 193 LEERMKSKPSLSSGTTKGLAKSALKHVLEGDFYAREFELGFIKKGDP 239
>UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5;
Plasmodium|Rep: Proteasome subunit alpha, putative -
Plasmodium falciparum (isolate 3D7)
Length = 284
Score = 179 bits (436), Expect = 7e-44
Identities = 107/280 (38%), Positives = 154/280 (55%), Gaps = 38/280 (13%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVP------D 606
S + +DRH+TIFSP+G LYQ+EYA+KA+ +TSV ++G + AV+ +Q+K+ D
Sbjct: 5 SQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQD 64
Query: 605 RLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRI 426
+LLD ++T+++ +TD IGC M GM D S V +AR EA+ + Y G + LCR I
Sbjct: 65 KLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNI 124
Query: 425 ADISQVYTQNAEMRPLGCSM------------------------MLIAYDDEAGPCVYKT 318
D QVYTQ+A MR CS M+I D+ P ++K
Sbjct: 125 CDKIQVYTQHAYMRLHACSNIYIYIYMNICTCVFIFLHKCVKCGMIIGIDENNKPELFKF 184
Query: 317 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQ--------LAISCLSQVL 162
DPSG+ Y+A G K + + LE+ L+KR + I LAI L +L
Sbjct: 185 DPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQTIL 244
Query: 161 SVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 42
+ D K+SEIE+ +VS N F ++E EID +LT IAE+D
Sbjct: 245 AFDLKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAERD 284
>UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei brucei
Length = 266
Score = 174 bits (423), Expect = 3e-42
Identities = 95/247 (38%), Positives = 147/247 (59%), Gaps = 7/247 (2%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S AGFD++IT+FSPEG LYQVEYA KA+ GL +VA+R DA +V Q VPD+L+ P
Sbjct: 2 SRAGFDKYITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPE 61
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
++T L+ + D G +TG D ++ V +AR EA+ ++Y+YG + V +L + D++QV
Sbjct: 62 TITSLYNVNDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQV 121
Query: 407 YTQNAEMRPLGCSMMLIAYD--DEAG---PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYL 243
TQ A MR +G M + + DE G P +Y DP+G + A A G K ++ A+L
Sbjct: 122 RTQQAGMRLMGTIMTFVGMEQNDEDGAWIPQIYCVDPAG-GAAVHACAVGKKQIEACAFL 180
Query: 242 EKKLKKR--SDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDR 69
EKK K LS +A +A++ L L ++S +E+G + D+ F +++ E+ +
Sbjct: 181 EKKQKNAPFHTLSQKEAAMIALAALQSALGESLRASGVEVGRCTADDHHFLRVSDREVKK 240
Query: 68 HLTAIAE 48
LT +A+
Sbjct: 241 WLTPLAK 247
>UniRef50_P23638 Cluster: Proteasome component Y13; n=3;
Saccharomycetaceae|Rep: Proteasome component Y13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 258
Score = 161 bits (392), Expect = 2e-38
Identities = 85/200 (42%), Positives = 120/200 (60%), Gaps = 1/200 (0%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD-PA 588
S +D TIFSPEGRLYQVEYAL++I+ G T++ + +D V+AA+RKV LL+
Sbjct: 3 SRRYDSRTTIFSPEGRLYQVEYALESISHAG-TAIGIMASDGIVLAAERKVTSTLLEQDT 61
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
S L+ L D+I + G+ AD+ + AR A N+ Y +IPV IL RR++DI Q
Sbjct: 62 STEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQG 121
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ+ +RP G S + YDD G +Y ++PSG Y +KA++ GA T L+ K
Sbjct: 122 YTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYK 181
Query: 227 KRSDLSTDDAIQLAISCLSQ 168
D+ DDAI+LA+ LS+
Sbjct: 182 --DDMKVDDAIELALKTLSK 199
>UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29;
Archaea|Rep: Proteasome subunit alpha - Methanococcus
jannaschii
Length = 261
Score = 160 bits (388), Expect = 5e-38
Identities = 83/239 (34%), Positives = 144/239 (60%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
+ +DR IT+FSPEGRLYQVEYA +A+ +G T++ + D V+A R++ +L+ S+
Sbjct: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRG-TTAIGIACKDGVVLAVDRRITSKLVKIRSI 65
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
+F + D + +G++AD+R + RAR EA ++ YG EI + +L ++I DI Q YT
Sbjct: 66 EKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT 125
Query: 401 QNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR 222
Q+ +RP G S +LIA D+ +++TDPSG YKA A G+ LEK+ R
Sbjct: 126 QHGGVRPFGVS-LLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY--R 182
Query: 221 SDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
D++ D+ ++LAI+ L++ + D K +++ +++ + +F+ + EI + + + +K
Sbjct: 183 DDITLDEGLELAITALTKA-NEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240
>UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;
Eukaryota|Rep: Alpha 2 subunit of 20S proteasome -
Ostreococcus tauri
Length = 270
Score = 159 bits (385), Expect = 1e-37
Identities = 88/238 (36%), Positives = 131/238 (55%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S + +T FSP G L Q+++AL AI+ G TS+ ++ D V+A ++K+P L+D +
Sbjct: 37 SDGRYSFSLTTFSPSGELVQIKHALAAISAGA-TSLGIKAVDGVVLATEKKLPSTLVDAS 95
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+V + LTD IG +GM D R AR E + Y IPV L R A + Q
Sbjct: 96 TVKKIATLTDDIGIAYSGMGPDFRVLTRMARKETQTYYRTYKESIPVSQLVRETATVMQE 155
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
+TQ +RP G S+++ Y DE+GP +Y+ DPSG Y ++KA A G V+ +LEK+
Sbjct: 156 FTQQGGVRPFGVSLLMAGY-DESGPSLYQVDPSGSYFAWKASAIGKNMVNAKTFLEKRYS 214
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
D+ +DAI AI L + + IEIG+V D KFR+L+ +EI +L +
Sbjct: 215 --DDIELEDAIHTAILTLKEGFDGQISADNIEIGIVGADR-KFRILSTSEIADYLEEV 269
>UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8;
Euryarchaeota|Rep: Proteasome subunit alpha -
Methanococcus maripaludis
Length = 259
Score = 155 bits (375), Expect = 2e-36
Identities = 82/240 (34%), Positives = 139/240 (57%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
++G+DR ITIFSPEGRLYQVEYA +A+ +G T+V ++ D V+A R++ +L+D +S
Sbjct: 7 ASGYDRAITIFSPEGRLYQVEYAREAVRRG-TTAVGIKCKDGVVLAVDRRITSKLIDVSS 65
Query: 584 VTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVY 405
+ +F + D I +G++AD+R + RAR EA + YG I V L ++I DI Q Y
Sbjct: 66 IEKIFQIDDHIVAATSGLVADARVLIDRARIEAQMNRVSYGEAITVEALAKKICDIKQAY 125
Query: 404 TQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKK 225
TQ+ RP G ++++ D + +++TDPSG YKA A G+ LE K +
Sbjct: 126 TQHGGARPFGLALLITGIDRHSAR-LFETDPSGALIEYKATAIGSGRPIAMEVLESKYDE 184
Query: 224 RSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
+++ + ++LA+ LS+ + + K I++ ++ ++ EI++ + A+ EK
Sbjct: 185 --NMTVSEGMELALYALSKT-TEELKPENIDMAIIKDSGKLVEKISVDEIEKIVKAVYEK 241
>UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia
intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia
ATCC 50803
Length = 247
Score = 154 bits (374), Expect = 2e-36
Identities = 84/243 (34%), Positives = 135/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
++ GFD+ +T+F+PEG+L+QVEYA +A+ GL+ VA+R D V+ +Q + DRL+D A
Sbjct: 3 TTEGFDQALTVFNPEGKLFQVEYAFRAVKTSGLSHVAIRCLDGVVLVSQLQSADRLVDTA 62
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ T + + + C++ G IAD R + R R EA ++ K+ + ILC R+ADI+Q+
Sbjct: 63 NNTFIHEINETSACMICGRIADGRRVIDRVRSEAVDFFRKWNYQPTADILCTRLADINQI 122
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAG-PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
YTQ A RP G + +D E ++KTDP+G Y A+A G K V+ L ++
Sbjct: 123 YTQEAWQRPFGNIAVFAGWDPEQDRSLLFKTDPAGTNTGYFAIAVGVKEVELADALTVQV 182
Query: 230 KKRSD---LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLT 60
K + ST + A+ V+S ++E+ + +K + LT E+DR L
Sbjct: 183 KSFPNGICESTQKGLDCALKIFQNVISTGLTGDDVEVAIYTKTG--LKRLTPIEVDRRLG 240
Query: 59 AIA 51
+A
Sbjct: 241 ELA 243
>UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54;
Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo
sapiens (Human)
Length = 234
Score = 151 bits (366), Expect = 2e-35
Identities = 88/236 (37%), Positives = 131/236 (55%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+ +T FSP G+L Q+EYAL A+ GG SV ++ + V+A ++K L D SV
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAV-AGGAPSVGIKAANGVVLATEKKQKSILYDERSVH 63
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ +T IG V +GM D R V RAR A + Y IP L +R+A + Q YTQ
Sbjct: 64 KVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQ 123
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+ +RP G S+++ + +E P ++++DPSG Y ++KA A G V+G +LEK+ +
Sbjct: 124 SGGVRPFGVSLLICGW-NEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNE-- 180
Query: 218 DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIA 51
DL +DAI AI L + IE+G+ ++ FR LT TE+ +L AIA
Sbjct: 181 DLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAG--FRRLTPTEVKDYLAAIA 234
>UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24;
Bilateria|Rep: Proteasome subunit alpha type-7 -
Carassius auratus (Goldfish)
Length = 251
Score = 149 bits (360), Expect = 1e-34
Identities = 85/241 (35%), Positives = 137/241 (56%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
+A +DR IT+FSP+G L+QVEYA +A+ +G T+V +RG D V+ ++K +L + +
Sbjct: 2 AARYDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGKDIVVLGVEKKSVAKLQEERT 60
Query: 584 VTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVY 405
V + AL + + G+ AD+R + RAR E + + + V + R IA + Q Y
Sbjct: 61 VRKICALDEHVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRY 120
Query: 404 TQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKK 225
TQ+ RP G S +++ +D + P +Y+TDPSG Y ++KA A G +LEK
Sbjct: 121 TQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTD 180
Query: 224 RSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
+ S +DAI+LAI L +V+ K+ IE+ V+ ++ P ++L EI+ L A EK
Sbjct: 181 EAIASDNDAIKLAIKALLEVVQSGGKN--IELAVIRRNQP-LKILESKEIET-LVAEIEK 236
Query: 44 D 42
+
Sbjct: 237 E 237
>UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1;
Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha
subunit - Hyperthermus butylicus (strain DSM 5456 / JCM
9403)
Length = 243
Score = 148 bits (359), Expect = 2e-34
Identities = 79/232 (34%), Positives = 131/232 (56%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+DR +FSP+GRL+QVEYA++A +G T V +R D V+ A++K L+D +
Sbjct: 11 GYDRSTAMFSPDGRLFQVEYAMEAAKRGW-TMVGVRARDGVVIVAEKKKTSPLIDIEQLE 69
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
++ + + IG G +D R + AR A +++ YG +IPV L R+I D+ Q+YTQ
Sbjct: 70 KVYMVDEHIGAGFVGFGSDGRVLIDYARQLAIQYKFIYGEKIPVEYLTRQICDLMQLYTQ 129
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+ +RP G +++++ DD +GP ++ +PSG Y SYKA G G A + + R
Sbjct: 130 HGGVRPFGVTLLIVGVDD-SGPKLFVAEPSGQYMSYKAHGLGQG--GGQAIEILQREYRD 186
Query: 218 DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHL 63
D+ + AI L I ++ V+ +E+GV +FR LT+ E+ +++
Sbjct: 187 DIDVEGAILLGIRAVASVMEGKPTPETLEVGVADTRTGRFRKLTKEELLKYI 238
>UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4;
Thermoplasmatales|Rep: Proteasome subunit alpha -
Picrophilus torridus
Length = 234
Score = 146 bits (353), Expect = 8e-34
Identities = 82/231 (35%), Positives = 134/231 (58%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR IT+FSP+GRL+QVEYA +A+ +G T++ ++ D + +++KV RL++ S+
Sbjct: 8 YDRAITVFSPDGRLFQVEYAREAVKKGS-TALGIKFKDGVALISEKKVRSRLVEKTSLEK 66
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ + DR+ V +G++AD+R + AR + YGS + + L +R+AD Q YTQ
Sbjct: 67 IQLIDDRVAAVTSGLVADARVLIDFARISDQQEKVTYGSLMNIENLVKRVADQMQQYTQY 126
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+RP G S ++ A D GP ++ DP+G YK V+ GA AYLEK+ K+ +
Sbjct: 127 GGVRPYGVS-IIFAGLDSIGPRLFDCDPAGTINEYKCVSIGAGKDQVTAYLEKEYKE--N 183
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHL 63
LS D+AI++ I+ L ++ + E EI + K F V T E+ ++L
Sbjct: 184 LSEDEAIRMGIAALKSAVADESSMKEPEIASI-KMGETFHVFTSEEVSKYL 233
>UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;
n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta
subunit - Cenarchaeum symbiosum
Length = 245
Score = 142 bits (345), Expect = 8e-33
Identities = 82/238 (34%), Positives = 129/238 (54%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+DR IT+FSP+GRLYQVEYA++ + +G + +V ++ T V+A + K P RL ++
Sbjct: 7 GYDRAITVFSPDGRLYQVEYAIETVRRGTI-AVGVKSTGGIVIAVEEK-PRRLQISDTIQ 64
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+F + D +G G I D+RSQV AR+ + + + Y + V + + +AD Q +TQ
Sbjct: 65 KIFQVDDHLGVAAAGYIPDARSQVENARFFSQSNRMMYDESVEVEAVAKHLADQCQQFTQ 124
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
A +RP G ++++ DD ++ TDPSG Y SY A+A GA + +LEK K
Sbjct: 125 YAGVRPFGVALIIGGVDDGGKGQLFLTDPSGTYISYDAIAIGAGSEQVTEFLEKSYKPG- 183
Query: 218 DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
S +DA LA + + S I + VS DN +F ++ + E+ A K
Sbjct: 184 --SMEDAAVLAAAAIRIAGEETDTESHIRMARVSADNRRFEMVPDGEVASFAAKAAAK 239
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 142 bits (344), Expect = 1e-32
Identities = 83/238 (34%), Positives = 126/238 (52%)
Frame = -2
Query: 776 GSRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLL 597
G +DR ITIFSP+GRLYQVEYA +A+ +G S+ +R +D V+A +++ L+
Sbjct: 3 GQNQQQAYDRGITIFSPDGRLYQVEYAREAVKRG-TASIGVRTSDGVVLAVDKRIRSPLM 61
Query: 596 DPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADI 417
+ +SV + D IG G +AD+R + AR +A Q +YG + V L + I D
Sbjct: 62 ERSSVEKIHKADDHIGIASAGHVADARQLIDFARRQAQVNQLRYGEPVGVETLTKEITDY 121
Query: 416 SQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
Q YTQ RP G + ++I P +++TDPSG +KA+A GA D YLE+
Sbjct: 122 IQQYTQVGGARPFGVA-LIIGGIVNGEPRLFETDPSGTPYEWKALAVGADRGDIRDYLEE 180
Query: 236 KLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHL 63
+ DL D+ + LA++ L+ V + I + V + F LT+ E + HL
Sbjct: 181 HYDEGMDL--DEGVDLALAALASVNDDELSPEGIGVATVDVETETFGQLTDEEKEAHL 236
>UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6;
Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus
acidocaldarius
Length = 242
Score = 142 bits (343), Expect = 1e-32
Identities = 80/232 (34%), Positives = 123/232 (53%), Gaps = 2/232 (0%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
++ G+DR ITIFSP+G LYQV+YA +A+ +G T++ ++ V+ A+++ +LLD
Sbjct: 6 AAMGYDRAITIFSPDGSLYQVDYAFEAVKRGW-TTLGVKTKSGVVLLAEKRKATQLLDVD 64
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ +F L D +GC G+ +D R + AR +A + Y I + L + I+D+ Q
Sbjct: 65 GIEKIFMLDDHVGCTFAGLASDGRILIDYARSQALQHRLIYDEPISIEYLTKVISDVKQA 124
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ+ +RP G ++++ D P + T+PSG + Y AVA G YLEK K
Sbjct: 125 YTQHGGVRPFGVALIVGGIDKGKQPKLLMTEPSGQFMPYYAVAIGQGGYTATEYLEKNYK 184
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFK--SSEIEIGVVSKDNPKFRVLTETE 78
+ DL I LA+ L L K S +EIG D+ F+ LT E
Sbjct: 185 E--DLDIQSTILLALRALMATLKPGEKLNYSSVEIGYADVDSGTFKKLTTEE 234
>UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like;
n=116; Eukaryota|Rep: Proteasome subunit alpha
type-7-like - Homo sapiens (Human)
Length = 256
Score = 141 bits (341), Expect = 2e-32
Identities = 82/243 (33%), Positives = 140/243 (57%), Gaps = 6/243 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR IT+FSP+G L+QVEYA +A+ +G T+V +RGT+ V+ ++K +L D +V
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGTNIVVLGVEKKSVAKLQDERTVRK 63
Query: 575 LFALTDRIG---CVMT---GMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
+ AL D + V+T G+ AD+R + RAR E + + + V + R IA +
Sbjct: 64 ICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLK 123
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
Q YTQ+ RP G S +++ +DD+ +Y+TDPSG Y ++KA A G +LEK
Sbjct: 124 QKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKN 183
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+ + S +AI+LAI L +V+ K+ IE+ ++ ++ P ++ + E++ ++T I
Sbjct: 184 YTEDAIASDSEAIKLAIKALLEVVQSGGKN--IELAIIRRNQP-LKMFSAKEVELYVTEI 240
Query: 53 AEK 45
++
Sbjct: 241 EKE 243
>UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48;
Eukaryota|Rep: Proteasome subunit alpha type-2 -
Drosophila melanogaster (Fruit fly)
Length = 234
Score = 139 bits (337), Expect = 7e-32
Identities = 83/230 (36%), Positives = 127/230 (55%)
Frame = -2
Query: 743 ITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFAL 564
+T FSP G+L Q+EYAL A++ GG SV + ++ V+A + K L + SV + +
Sbjct: 10 LTTFSPSGKLVQLEYALAAVS-GGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMI 68
Query: 563 TDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMR 384
+ IG V +GM D R V +AR A + Y IPV L +R+A + Q YTQ+ +R
Sbjct: 69 YNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVR 128
Query: 383 PLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTD 204
P G S+++ +D++ P +Y++DPSG Y ++KA A G V+G +LEK+ + DL D
Sbjct: 129 PFGVSLLICGWDNDR-PYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSE--DLELD 185
Query: 203 DAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
DA+ AI L + + IEIG+ D F+ L I +L +I
Sbjct: 186 DAVHTAILTLKEGFEGKMTADNIEIGIC--DQNGFQRLDPASIKDYLASI 233
>UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7;
Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum
aerophilum
Length = 243
Score = 137 bits (332), Expect = 3e-31
Identities = 78/236 (33%), Positives = 133/236 (56%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
AG+DR ITIFSPEG++YQVEYA +A+ +G T V ++ V+ A+++ L D +S+
Sbjct: 7 AGYDRAITIFSPEGKIYQVEYAGEAVKRGWPT-VGVKCKAGVVLTAEKRKISALFDSSSL 65
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
++ + + + +G++AD+R + AR A + ++ Y I V L + + ++ Q YT
Sbjct: 66 EKIYLIDEHVAASPSGLLADARILIDYARDVALSHRFIYDEPIDVEFLTKAVCNLKQQYT 125
Query: 401 QNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR 222
Q RP G + +LIA D G +Y+TDPSG Y Y A A GA++ +LEK K
Sbjct: 126 QFGGARPFGVA-LLIAGVDRHGARLYQTDPSGVYIGYFATAIGAESGTITEFLEKNYK-- 182
Query: 221 SDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
D+ + I+LA+ L+ + + S+ +E+ + + K R +++ E+ LT +
Sbjct: 183 FDMEMGECIELALKALASAVEIT-DSANVEVAYATIEEKKMRKMSQDEVASLLTKL 237
>UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7;
n=3; Ascomycota|Rep: Probable proteasome subunit alpha
type-7 - Schizosaccharomyces pombe (Fission yeast)
Length = 259
Score = 136 bits (330), Expect = 5e-31
Identities = 74/215 (34%), Positives = 124/215 (57%), Gaps = 1/215 (0%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
+G+DR +++FSP+GRL QVEY +A+ +G T++ALRG + V+ +RK +L + ++
Sbjct: 2 SGYDRALSVFSPDGRLLQVEYGQEAVRRG-TTAIALRGNECIVIGVERKNVPKLQNVSNF 60
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
+ + + + G+ AD+R + +AR EA N + + + L R +A + Q YT
Sbjct: 61 QKIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYT 120
Query: 401 QNAEMRPLGCSMMLIAYD-DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKK 225
Q+ +RP G S ++ +D + P VY+T+P+G Y ++KA A G + YLEK K+
Sbjct: 121 QSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKE 180
Query: 224 RSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVV 120
LS D+ I LA+S L +V V S IE+ ++
Sbjct: 181 --GLSRDETIHLAVSSLLEV--VQTASGNIELAIM 211
>UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4;
n=5; Eukaryota|Rep: Probable proteasome subunit alpha
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 248
Score = 136 bits (330), Expect = 5e-31
Identities = 76/227 (33%), Positives = 127/227 (55%), Gaps = 2/227 (0%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD-PA 588
S +D TIFSPEGRLYQVEYAL+AIN G+ ++ + D V+AA++KV +LL+
Sbjct: 2 SRSYDSRTTIFSPEGRLYQVEYALEAINHAGV-ALGIVAKDGIVLAAEKKVTSKLLEQEE 60
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
S L+ + D + C + G+ AD+ + AR + + E+P L RR+ D+ Q
Sbjct: 61 SAEKLYHIGDNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQG 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ +RP G S + +D G +++++PSG Y S++A + G + + + ++ K
Sbjct: 121 YTQYGGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYK 180
Query: 227 KRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKDNPKFRVL 90
D++ D+A +A+ LS+ L S +IE ++KD K +++
Sbjct: 181 --DDINLDEASAMAVKFLSKTLDSNSLTHEKIEFATITKDTTKNKMV 225
>UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2;
Giardia intestinalis|Rep: Proteasome subunit alpha type
- Giardia lamblia ATCC 50803
Length = 214
Score = 135 bits (327), Expect = 1e-30
Identities = 77/212 (36%), Positives = 123/212 (58%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
S +D +T+FSP+G L QVE+A KA+ +G ++VA+R V+A +RK RL DP +
Sbjct: 2 SGKYDSSLTVFSPDGHLIQVEHAHKAVERG-TSAVAVRSAAGIVLAIERKQTARLQDPRA 60
Query: 584 VTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVY 405
+F + D I G+ AD+R + RAR E ++ Y V I+ + +A I Q +
Sbjct: 61 SQKIFDVDDHIIATFAGLTADARVLIDRARLECQAYRMTYDVAPSVEIIAKAVASILQSH 120
Query: 404 TQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKK 225
T RP G S++L A +D G V+ DPSG Y +KA+A G + V +LEKKLK+
Sbjct: 121 THRGGTRPFGVSIIL-AGNDLNGSHVFMCDPSGVYTEWKALAIGNQCVTIIEFLEKKLKE 179
Query: 224 RSDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 129
+T+DA+ LA + LS+++ V+ ++ + ++
Sbjct: 180 GEPQNTNDALSLAKAALSELIDVNDETFQCKV 211
>UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum
pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix
Length = 258
Score = 135 bits (327), Expect = 1e-30
Identities = 71/212 (33%), Positives = 115/212 (54%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR TIFSPEG LYQV YA +A+ +G TS+ ++ + V+AA+++ L+D +
Sbjct: 12 YDRAATIFSPEGDLYQVRYAFEAVKKGW-TSLGIKTNEGVVIAAEKRFIGPLVDIDDIDK 70
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
++ + D IG GM D R + AR + YG PV ++ + +AD+ Q YTQ+
Sbjct: 71 IYKIDDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQH 130
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+RP G +++ + + VY+TDP G Y S+KA+A G+ N EK RSD
Sbjct: 131 GGVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEMFEKHY--RSD 188
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVV 120
+S ++A +LA+ L ++ + E I +
Sbjct: 189 MSLEEATKLALKILYAIIRKTVEDKEKAIATL 220
>UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5;
Magnoliophyta|Rep: Proteasome subunit alpha type-4 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 250
Score = 135 bits (327), Expect = 1e-30
Identities = 71/217 (32%), Positives = 120/217 (55%), Gaps = 2/217 (0%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA- 588
S +D TIFSPEGRLYQVEYA++AI G +++ + D V+ ++KV +LL +
Sbjct: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGNAG-SAIGILSKDGVVLIGEKKVTSKLLQTST 60
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
S ++ + D + C + G+++D+ + AR +A + + Y +PV L + + D Q
Sbjct: 61 SAEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQG 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ +RP G S + +D G +Y +DPSG Y +KA A GA + L++ K
Sbjct: 121 YTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYK 180
Query: 227 KRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVV 120
D + ++A++LA+ L++ + S S ++E+ V
Sbjct: 181 --DDATREEAVELALKVLTKTMDSTSLTSEKLELAEV 215
>UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6;
Eukaryota|Rep: Proteasome subunit alpha type-1 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 134 bits (324), Expect = 3e-30
Identities = 72/241 (29%), Positives = 132/241 (54%), Gaps = 3/241 (1%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D IT FSP GR++Q+EYA++A+ QGG +VAL+ AV+ + ++ L +
Sbjct: 6 YDSDITTFSPSGRIHQIEYAMEAVKQGG-AAVALKSKQFAVLVSLKRSSSEL--GSYQKK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + D +G ++G+ AD+R R E +N+ Y Y S++ V L ++AD QV+TQ
Sbjct: 63 IFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQR 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G +++ Y D+ G +Y+T PSG + YK+++ G+++ YLEK + +
Sbjct: 123 YGRRPYGVGLLVAGY-DQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEE 181
Query: 215 LSTDDAIQLAISCLSQVL-SVD--FKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
+ + I + L + + + D S + IG+V + P F+++ E + +L + +
Sbjct: 182 CTLEQLITHGLRALRETIPNTDDTLNSKNVSIGIVGEGQP-FKIIEEADAQPYLNLLENE 240
Query: 44 D 42
+
Sbjct: 241 E 241
>UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;
Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo
sapiens (Human)
Length = 261
Score = 134 bits (323), Expect = 4e-30
Identities = 79/245 (32%), Positives = 133/245 (54%), Gaps = 4/245 (1%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
S +D TIFSPEGRLYQVEYA++AI G T + + D ++AA+R+ +LLD
Sbjct: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKLLDEVF 60
Query: 584 VTH-LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ ++ L + + C + G+ +D+ R A + +Y IP L + DI Q
Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ RP G S++ I +D G +Y++DPSG Y +KA G + + L++ K
Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNPK--FRVLTETEIDRHLTA 57
+ +++ A+ LAI L++ + V S+E +EI ++++N K RVL + E+++ +
Sbjct: 181 E-GEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
Query: 56 IAEKD 42
E++
Sbjct: 240 HEEEE 244
>UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4;
Eukaryota|Rep: Proteasome subunit alpha type-4 -
Dictyostelium discoideum (Slime mold)
Length = 250
Score = 134 bits (323), Expect = 4e-30
Identities = 77/234 (32%), Positives = 128/234 (54%), Gaps = 6/234 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA-SVT 579
+D+ TIFSPEGR+YQVEYA+ AI G T V + D V+AA++K +LLD + S++
Sbjct: 5 YDQRTTIFSPEGRVYQVEYAMTAIRHAGAT-VGILAKDGIVLAAEKKTTAKLLDSSTSIS 63
Query: 578 H-LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
+F + + + C + G+ +D+ + AR + + Y+Y +PV L +I D Q YT
Sbjct: 64 EKMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYT 123
Query: 401 QNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVD-GNAYLEKKLKK 225
Q +RP G S + +D G +Y++DPSG + +KA + G + + L K
Sbjct: 124 QYGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSNYK- 182
Query: 224 RSDLSTDDAIQLAISCLSQVLS-VDFKSSEIEIGVVSK--DNPKFRVLTETEID 72
D+S +A+QLA+ L++ + + S ++E +K DN + + T E+D
Sbjct: 183 -PDISLKEALQLALKVLTKTMDRSNINSEKLEFSYFTKQGDNVVYHIFTAAELD 235
>UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2;
Eukaryota|Rep: Proteasome subunit alpha type-5 -
Entamoeba histolytica
Length = 247
Score = 132 bits (319), Expect = 1e-29
Identities = 75/241 (31%), Positives = 133/241 (55%), Gaps = 5/241 (2%)
Frame = -2
Query: 752 DRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHL 573
D + FS EGRL+QVEYA +A+ G T + ++ + V+A ++++ L+ +S+ +
Sbjct: 9 DHGVNTFSSEGRLFQVEYATEAMKLGS-TVIGIQTKEGVVLAVEKRISSPLMLGSSIEKI 67
Query: 572 FALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNA 393
+ D IG ++G+ AD+R+ + AR EA N ++ Y I V ++ + I+D+S + + +
Sbjct: 68 IEIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGS 127
Query: 392 E-----MRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
RP G + +LIA DE GP +++TDPSG + + A A GA T + L +K
Sbjct: 128 RKKKVMSRPFGVA-LLIAGVDETGPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYN 186
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
K ++ +A LA+S L QV+ S +E+ +V+ + KF ++ I+ + I E
Sbjct: 187 K--SMTLREAEILALSTLKQVMEEKLNSKNVEVALVTVEKKKFEIMDTAFIENLIGEIKE 244
Query: 47 K 45
+
Sbjct: 245 E 245
>UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2;
Sophophora|Rep: Proteasome subunit alpha type -
Drosophila melanogaster (Fruit fly)
Length = 289
Score = 129 bits (311), Expect = 1e-28
Identities = 77/240 (32%), Positives = 128/240 (53%), Gaps = 2/240 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D T +SP+GRL+QVEYA++A+ QG T V L+GTD AV+AA + D ++
Sbjct: 6 YDNDTTTWSPQGRLFQVEYAMEAVKQGAAT-VGLKGTDYAVLAALCRTSK---DTNTLQR 61
Query: 575 -LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ + D +G + G+ AD+R R E +++ Y +E PV L + + Q TQ
Sbjct: 62 KIMPVDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQ 121
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+ RP G +++ Y DE GP +Y+ P+ + KA+A G+++ YLE+ ++
Sbjct: 122 RYDRRPYGVGLLVAGY-DEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFE 180
Query: 218 DLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 42
D D+ I AI + L S D ++ I + +V KD P F++ TE E +++ + D
Sbjct: 181 DCDMDELICHAIQAIRGSLGSDDVENLTINVAIVGKDVP-FKMFTEAENQKYVKLVKAMD 239
>UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7;
Aconoidasida|Rep: Proteasome subunit alpha type -
Plasmodium yoelii yoelii
Length = 278
Score = 128 bits (309), Expect = 2e-28
Identities = 69/236 (29%), Positives = 131/236 (55%)
Frame = -2
Query: 779 NGSRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRL 600
+ S S +DR IT+FSP+G L QVE+AL+A+ +GG +VA++ ++ AV+A ++K +L
Sbjct: 32 SSSGSKMSYDRAITVFSPDGHLLQVEHALEAVKKGGC-AVAIKSSNFAVLAVEKKNIPKL 90
Query: 599 LDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIAD 420
+P + L L + +G+ AD+R V + R E + PV + + +A
Sbjct: 91 QNPRTTEKLVKLDEHTCLAFSGLNADARILVNKTRLECQRYYLNMDQPAPVDYIAKYVAR 150
Query: 419 ISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLE 240
I Q +T +RP G + ++ + + C+Y+T+PSG Y S+KA A G +LE
Sbjct: 151 IQQKFTHRGGVRPFGIATLITGFKNNKEICIYQTEPSGIYASWKAQAIGKNAKVVQEFLE 210
Query: 239 KKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 72
K ++ ++ ++ + LA+ + +V V+ S +E+ +++++ K+ + E E++
Sbjct: 211 KNYQE--NMEKNECLLLALKAIFEV--VELSSKNVELALLTEEELKY--IDEQEVN 260
>UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9;
Eukaryota|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 271
Score = 128 bits (309), Expect = 2e-28
Identities = 75/246 (30%), Positives = 128/246 (52%), Gaps = 6/246 (2%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA- 588
S +D T FSPEGRLYQVEYAL+AIN T V + + ++ A + + +LLD
Sbjct: 12 SRRYDSRTTTFSPEGRLYQVEYALEAINNAAPT-VGILCKEGVILGADKAIVSKLLDQGK 70
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
S+ ++ + I + G+ AD+ + +AR ++ +QY YG E PV L +I D Q
Sbjct: 71 SLEKIYTIDRHIIAAVAGLTADANILIAQARIDSQRYQYTYGEEQPVEQLVTQICDRKQS 130
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ +RP G S + YD G +Y++DPSG + +KA A G + L+++
Sbjct: 131 YTQFGGLRPFGVSFLFAGYDKNYGYQLYQSDPSGNFSGWKATAIGQNNQTATSLLKQEWN 190
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNP----KFRVLTETEIDRHL 63
+ DL+ + + L L++ + +++ E +++ +N ++L+E EI L
Sbjct: 191 E--DLTLEQGLHLVAKVLTKTMDTTSPTADKFEFSILTHNNESNKCSQKILSEKEIGELL 248
Query: 62 TAIAEK 45
+ ++
Sbjct: 249 EKVQKE 254
>UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1;
Methanocorpusculum labreanum Z|Rep: Proteasome alpha
subunit - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 272
Score = 128 bits (308), Expect = 2e-28
Identities = 78/251 (31%), Positives = 129/251 (51%), Gaps = 5/251 (1%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+DR IT+FSP+GRLYQVEYA +A+ +G T+V ++ V+ ++V RLL+P+S+
Sbjct: 10 GYDRAITMFSPDGRLYQVEYAREAVKRG-TTAVGIKCKTGVVLLVDKRVNSRLLEPSSIE 68
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+F + + IG +G++ D+R V RAR EA + YG + V L +++ D Q YT
Sbjct: 69 KIFRIDEHIGVASSGLVGDARILVDRARIEAQINRVSYGEPVDVETLAKKLCDHMQSYTL 128
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVY---KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
RP G ++++ + Y +TDPSG Y A G E++ K
Sbjct: 129 FGGARPYGTALLIAGAESSPTGTKYHLFETDPSGTLLEYSATGIGIGRPAVIKLFEQEYK 188
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKF--RVLTETEIDRHLTAI 54
+ S ++A+ L + L F + +EIG+ + + K + +ET ++ I
Sbjct: 189 E--TCSAEEAVLLGLKALHTATEGKFDMNTVEIGIAGEYSKKHSSKKESETANGTKISTI 246
Query: 53 AEKD*RVD*IK 21
A + VD +K
Sbjct: 247 AFRKLNVDEVK 257
>UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 283
Score = 92.7 bits (220), Expect(2) = 3e-28
Identities = 51/139 (36%), Positives = 83/139 (59%), Gaps = 2/139 (1%)
Frame = -2
Query: 743 ITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFAL 564
+T FSP G+L Q+EYAL A+NQG +T++ ++ T+ V+A ++K L DP+S++ + +
Sbjct: 9 LTTFSPSGKLVQIEYALNAVNQG-VTALGIKATNGIVLATEKKSSSPLTDPSSLSKISLV 67
Query: 563 TDRIGCVMTGMIADSRSQV*RARYEAANWQYK--YGSEIPVHILCRRIADISQVYTQNAE 390
T IG V GM D R V +AR + ++ YK Y P IL + +A + Q TQ+
Sbjct: 68 TPNIGMVYAGMGPDYRVLVDKAR-KVSHSGYKRIYNEYPPTRILVQDVARVVQEATQSGG 126
Query: 389 MRPLGCSMMLIAYDDEAGP 333
+RP G S+++ +D+ P
Sbjct: 127 VRPYGVSLLIAGWDEGIPP 145
Score = 56.0 bits (129), Expect(2) = 3e-28
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 14/109 (12%)
Frame = -2
Query: 344 EAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQV 165
+ GP +Y+ DPSG Y +KA A G +LEK+ + L +DA+ +A+ L +
Sbjct: 175 KGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYTE--GLELEDAVHIALLTLKET 232
Query: 164 LSVDFKSSEIEIGVV--------------SKDNPKFRVLTETEIDRHLT 60
+ + IEIG+V P+FR L+ EI+ +LT
Sbjct: 233 IEGEMNGDSIEIGIVGPPADHLLGVEGVEGAQGPRFRKLSPQEIEDYLT 281
>UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 251
Score = 127 bits (306), Expect = 4e-28
Identities = 75/232 (32%), Positives = 126/232 (54%), Gaps = 2/232 (0%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
+G+D ++ FSP+GR++QVEYA KA++ G T++A+ V A + V +++ +
Sbjct: 6 SGYDSSVSTFSPDGRVFQVEYANKAVDNSG-TTIAMIYNSGIVFAVDKYVASKMMVAGTN 64
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
+FA+ ++IGC + G + DS V AR E+ N+Q YG+ IP+ +L RIA +T
Sbjct: 65 RRVFAIDNQIGCCVAGFVTDSNKIVSIARSESLNYQKIYGNPIPIRVLAERIAMYMHNFT 124
Query: 401 QNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR 222
+RP GCS++L D + G +Y PSG Y A+A G LEK ++K
Sbjct: 125 LYGSVRPFGCSILLGGLDQDRGVELYCIHPSGSCYKYCAMAVGKGRQFARTDLEKLMEK- 183
Query: 221 SDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSKDNP-KFRVLTETEID 72
+LS +DA+ A + Q K+ E+E+ + + +F ++ E +I+
Sbjct: 184 -NLSEEDALYEAARVIIQSREEGASKNLELEMAFIGPGSDFQFSIVPEKQIN 234
>UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome
(prosome macropain) subunit alpha type 4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Proteasome (prosome macropain) subunit alpha type 4 -
Strongylocentrotus purpuratus
Length = 257
Score = 126 bits (305), Expect = 5e-28
Identities = 77/245 (31%), Positives = 130/245 (53%), Gaps = 4/245 (1%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
S +D TIFSPEGRLYQVEYA++AI G TS+ + +D ++AA+R+ +LLD
Sbjct: 2 SRRYDSKTTIFSPEGRLYQVEYAMEAIGHAG-TSLGILASDGVLLAAERRNTHKLLDDVV 60
Query: 584 VT-HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ ++ L + C ++G+ +D+ R + +Y IP L + DI Q
Sbjct: 61 FSDKIYKLNSDMACSVSGITSDANVLTSELRLAGQRYFLQYQENIPNEQLVSTLCDIKQF 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ RP G S++ + +D G +Y++DPSG Y +KA G + + L+++ K
Sbjct: 121 YTQAGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEYK 180
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDN--PKFRVLTETEIDRHLTA 57
+ D A+ LA+ LS+ L + + E IEI +++++ K R+L E+ + +
Sbjct: 181 E-GDTDLKGALALAVKVLSKTLDMTKVTPEKIEIASLTREDGKTKIRILPVEELQKLIKE 239
Query: 56 IAEKD 42
E++
Sbjct: 240 HEERE 244
>UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 232
Score = 126 bits (303), Expect = 9e-28
Identities = 76/233 (32%), Positives = 124/233 (53%)
Frame = -2
Query: 752 DRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHL 573
D +T FS G+L Q+E ALKA++ GG V ++ + AV+A + K L++ + +
Sbjct: 5 DFSLTTFSSGGKLNQIESALKAVSLGG-QCVGVKAKNGAVIACESKPSSPLVEKVTNLKV 63
Query: 572 FALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNA 393
+ D +G V +G+ D + R + + + G E+P + + A Q YTQ
Sbjct: 64 QKINDNVGIVYSGVNTDFHVILKSLRKASIKYSLRLGVEMPTREVVKHAAHKMQYYTQIG 123
Query: 392 EMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDL 213
+RP G S+++I + +E GP +++ DPSG + ++KA A G ++ +LE++ + D
Sbjct: 124 GVRPFGVSLLIIGW-EELGPTLWQVDPSGTFWAWKATALGKRSDGSRTFLERRYSE--DQ 180
Query: 212 STDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
S DDAI AIS L + + IEIGVV + KFR L+ EI LT +
Sbjct: 181 SVDDAIHTAISTLKEGFDGQLTAELIEIGVVD-ETRKFRTLSTAEIRDFLTEV 232
>UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1;
Babesia bovis|Rep: Proteasome alpha 5 subunit, putative
- Babesia bovis
Length = 250
Score = 125 bits (302), Expect = 1e-27
Identities = 74/234 (31%), Positives = 124/234 (52%), Gaps = 7/234 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR + FSPEGR++QVEYAL AI G T++A+ + + A++ +V L++ S+
Sbjct: 8 YDRGVNTFSPEGRIFQVEYALGAIKLGS-TALAIATKEGVIFASEHRVNSPLMESVSLEK 66
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADI----SQV 408
+ + IGC M+G+IAD+R+ + R E AN ++ Y + + IAD+ S +
Sbjct: 67 IMEIDTHIGCTMSGLIADARTLIDHGRLECANHRFVYNEPLAIRSCVESIADMALDFSDI 126
Query: 407 Y---TQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
+ + RP G ++++ D + GP ++ DPSG YKA A G+ + L++
Sbjct: 127 FDTRKKKTMSRPFGVALLVGGIDID-GPSIWCVDPSGTSIKYKASAIGSAQEGAESVLQE 185
Query: 236 KLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEI 75
+ R D+S DA L + L QV+ + IE+ + + +FR TE EI
Sbjct: 186 RY--RDDMSFRDAELLVLEVLRQVMKDQMTTKNIEMARIKIHDRQFREYTEDEI 237
>UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11;
Eukaryota|Rep: Proteasome subunit alpha type-3 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 124 bits (298), Expect = 4e-27
Identities = 71/244 (29%), Positives = 128/244 (52%), Gaps = 1/244 (0%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S +G+D +++ +SP+G+L+QV+YA KA+ G T VA++ D V+ ++ VP ++L
Sbjct: 2 SSVGSGYDLYVSTYSPDGKLFQVDYANKAVENSG-TLVAIKAKDGVVLGVEKLVPSKMLC 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
S + + +G + G +AD+R + RAR EA N++ YG IP+ +L +RIA +
Sbjct: 61 SGSNRRVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYN 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
++T +RP GCS+ + D+ GP ++ +PSG Y + G LE+
Sbjct: 121 HMHTLYGSVRPFGCSIAITGI-DQYGPQLFLVEPSGSCVGYFGASLGKGKQAAKNELEE- 178
Query: 233 LKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTA 57
+ S+++ +AI+ + V V K E+E+G +S + + E+ A
Sbjct: 179 -IRFSEMTCREAIKEVSRIIYSVHDEVKDKDFELELGWISTETDNVHQIVPKELHDEGEA 237
Query: 56 IAEK 45
A++
Sbjct: 238 YAKQ 241
>UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7;
Trypanosomatidae|Rep: Proteasome subunit alpha type -
Leishmania major
Length = 285
Score = 123 bits (297), Expect = 5e-27
Identities = 71/222 (31%), Positives = 118/222 (53%), Gaps = 8/222 (3%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D T FSPEGRLYQVEYA++AI Q G T + + D V+A ++ VP L D ++
Sbjct: 5 YDSRTTTFSPEGRLYQVEYAVEAIQQAG-TVIGVCTKDGVVLAGEKMVPHPLFDSENMQD 63
Query: 575 -------LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADI 417
++ + + IGC + G+ +D+ + + AR A QY + I + LCR + D
Sbjct: 64 KNISGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRILCDE 123
Query: 416 SQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
Q+YTQ +RP G S +L+ +D G +Y T+PSG Y ++ A A G ++ L+K
Sbjct: 124 KQLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKK 183
Query: 236 KLKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSK 114
+++ +D + LA+ L + + + +E+ V+ K
Sbjct: 184 DW--HENMTLEDGMLLALRVLGKTMDTAKIDLGRVEVAVMRK 223
>UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;
core eudicotyledons|Rep: Proteasome subunit alpha
type-1-A - Arabidopsis thaliana (Mouse-ear cress)
Length = 278
Score = 123 bits (297), Expect = 5e-27
Identities = 77/230 (33%), Positives = 119/230 (51%), Gaps = 1/230 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +T +SP GRL+QVEYA++A+ QG ++ LR V+A K L +
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQGS-AAIGLRSRSHVVLACVNKAQSEL--SSHQRK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + D IG + G+ AD R R E+ N + Y S +PV L +AD +QV TQ
Sbjct: 63 IFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQR 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G +L+ DE+G +Y PSG Y Y+A A G+++ YLE++ + D
Sbjct: 123 SWKRPYGVG-LLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGD 181
Query: 215 LSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSKDNPKFRVLTETEIDR 69
S +D I+ AI + + L + KSS + ++ D P F L + I +
Sbjct: 182 SSREDLIKDAILAVRETLQGETLKSSLCTVAILGVDEP-FHFLDQEAIQK 230
>UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1;
Babesia bovis|Rep: Proteasome subunit alpha type 1 -
Babesia bovis
Length = 257
Score = 123 bits (296), Expect = 7e-27
Identities = 72/236 (30%), Positives = 119/236 (50%), Gaps = 2/236 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +SP+GRL+QVEYA++A+ QG V ++ V+ A R+ +L +
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMEAVKQG-TCCVGIKSQTHIVLCAVRRKSSKLAEYQD--K 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + + I VM+G+ +D++ V R E N ++ YG +I L IA SQ TQ
Sbjct: 63 IFCIGEHIAVVMSGITSDAKMIVNYMRNECLNNKFLYGCDITATKLVSLIAQKSQANTQT 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G +++ YDD G +Y+T PSG Y A A GA+ YLE+K+ +
Sbjct: 123 SSKRPFGVGLLVAGYDDRTGLHLYETCPSGNVVEYNATAFGARCQSAKTYLERKIANFEE 182
Query: 215 LSTDDAIQLAISCLSQVLSVD--FKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+ D I A+ + + D F + + ++ KD P F++LT E ++ +
Sbjct: 183 CNIDSLIYHAVKAVKMTIPSDGEFDVDMVTVCILGKDMP-FKLLTTAETQPYVDKV 237
>UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia
intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia
ATCC 50803
Length = 244
Score = 120 bits (289), Expect = 5e-26
Identities = 69/216 (31%), Positives = 114/216 (52%), Gaps = 2/216 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
FD T+FS +GRL QVEYA+KA+ +A+ D V AQ+K+P +L D +
Sbjct: 4 FDSRTTLFSQDGRLLQVEYAIKAVTIAA-PCLAILAQDGIVFVAQKKLPSKLSDQQTSEK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
++ + I C ++G+ +D+ + AR + W Y IPV +L + I+D+ Q YT +
Sbjct: 63 IYKIDSHIVCAVSGLTSDANILIDEARTYSQKWLAVYDEPIPVEVLVQYISDVKQNYTHH 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+RP G S + +D G +Y+TDPSG Y ++ A + G + + L++ + S
Sbjct: 123 GGLRPYGVSFLFGGWDAHLGFQLYQTDPSGNYSAWVATSIGGSAPEIASALKQNIADSSQ 182
Query: 215 -LSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSK 114
+ +A Q A+S L + + SS+ +EI V K
Sbjct: 183 KILLKEAQQYAVSALIKTTDITKVSSDKMEILTVVK 218
>UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13;
Eukaryota|Rep: Proteasome subunit alpha type-7 -
Trypanosoma brucei brucei
Length = 247
Score = 120 bits (289), Expect = 5e-26
Identities = 70/237 (29%), Positives = 129/237 (54%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR IT+FSP+G L+QVEYA +A+ +G L +V ++G D+ + A ++K +L D +
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVRKG-LCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRK 61
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
++ L + I G+ AD+R V A+ E ++ Y I V +L R +A + Q TQ+
Sbjct: 62 IYKLDEHIYLASAGLSADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQS 121
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G S ++ +++ P ++KT+PSG ++ A A G ++EK +
Sbjct: 122 SGSRPYGVSTIIGGFNENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNY--QDG 179
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
++ D + AI L + +V+ S IE+ V+ + K +++TE+ R + + ++
Sbjct: 180 MTRDRCVHFAIKALLE--AVESGSKNIELLVLERG--KAAYMSDTELHRFVVEVEKE 232
>UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;
Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo
sapiens (Human)
Length = 241
Score = 120 bits (288), Expect = 6e-26
Identities = 65/233 (27%), Positives = 130/233 (55%), Gaps = 5/233 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR + FSPEGRL+QVEYA++AI G T++ ++ ++ +A ++++ L++P+S+
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGS-TAIGIQTSEGVCLAVEKRITSPLMEPSSIEK 66
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ- 399
+ + IGC M+G+IAD+++ + +AR E N + Y + V + + +++++ + +
Sbjct: 67 IVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEE 126
Query: 398 ----NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
A RP G + +L DE GP ++ DPSG + A A G+ + + L++
Sbjct: 127 DADPGAMSRPFGVA-LLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVY 185
Query: 230 KKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 72
K ++ +AI+ ++ L QV+ ++ IE+ V + F + T+ E++
Sbjct: 186 HK--SMTLKEAIKSSLIILKQVMEEKLNATNIELATV-QPGQNFHMFTKEELE 235
>UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4;
Oryza sativa|Rep: Proteasome subunit alpha type-1 -
Oryza sativa subsp. japonica (Rice)
Length = 270
Score = 120 bits (288), Expect = 6e-26
Identities = 72/215 (33%), Positives = 114/215 (53%), Gaps = 1/215 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +T +SP GRL+QVEYA++A+ QG V LR AV+AA K L +
Sbjct: 6 YDTDVTTWSPAGRLFQVEYAMEAVKQGS-ACVGLRSRTHAVLAAANKAASEL--SSHQRK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + D G + G+ AD R R E N + Y + +PV L R+AD +QV TQ
Sbjct: 63 VFRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQR 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G +L+A DE+G +Y PSG Y Y+A A G+++ +LE++ + +D
Sbjct: 123 SWKRPYGVG-LLVAGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYND 181
Query: 215 LSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSK 114
+ + I+ A+S + + L + SS + +V +
Sbjct: 182 YTPEQLIKDALSAIKETLQGEKLTSSNCTVAIVGR 216
>UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1;
Anopheles gambiae str. PEST|Rep: Proteasome subunit
alpha type - Anopheles gambiae str. PEST
Length = 278
Score = 119 bits (287), Expect = 8e-26
Identities = 59/159 (37%), Positives = 93/159 (58%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S G+D + FSP+GR++Q+EYA KA+ G T + LRG D V+A ++ + +L +
Sbjct: 2 SSIGTGYDLSASQFSPDGRVFQIEYAAKAVENSG-TVIGLRGKDGVVLAVEKLITSKLYE 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
P T +F + IG ++GMI D R+ V AR EAA+++ + IP+ L R++
Sbjct: 61 PDCGTRIFTIDTSIGMAISGMITDGRAVVDIARQEAASYRQQNNRPIPLKQLNDRLSSYF 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYC 297
YT + +RP G S++L ++ +E GP +Y DPSG C
Sbjct: 121 HAYTLYSAVRPFGVSVILASWSEEKGPEMYMIDPSGVSC 159
>UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:
NEQ521 - Nanoarchaeum equitans
Length = 250
Score = 119 bits (286), Expect = 1e-25
Identities = 72/238 (30%), Positives = 120/238 (50%), Gaps = 3/238 (1%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+DR T+FSP+GRL QVEYA + Q T++ + +V +K+ ++ + P+S+
Sbjct: 11 GYDRASTLFSPDGRLLQVEYARTTVKQSP-TAIGMLYKTGVLVIGDKKIVEKFVIPSSIE 69
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
++ + D + G+I D R + RAR A ++Y YG I + L + IADI Q YTQ
Sbjct: 70 KVYIVDDHVIAAPAGIIGDGRVLIERARVIAQTYKYFYGHPIDIRGLVKEIADIKQEYTQ 129
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+RP G S++ DD G ++ T+P G + YK G YL K+ +
Sbjct: 130 IGGVRPFGVSIIFAGIDD-TGKHIFVTEPGGMFWEYKLAVIGEGEQKVLDYLGKEYNE-- 186
Query: 218 DLSTDDAIQLAISCLSQVL---SVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+LS AI+L + L + + + +++I V + K + + EI++ L I
Sbjct: 187 NLSLKKAIELGLKALYNFYKENNNELTAEKLDIAYVDEKTKKAKYVDVNEIEKILEKI 244
>UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei rhodesiense
Length = 266
Score = 119 bits (286), Expect = 1e-25
Identities = 73/233 (31%), Positives = 118/233 (50%), Gaps = 2/233 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D T +SP GRL+QVEYA +A+N G +V ++G D V+ A ++ P L
Sbjct: 6 YDTDTTTWSPTGRLFQVEYANEAVNNGS-AAVGVKGADYVVLTALKRNPVSGLSSYQ-EK 63
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
F L + +G ++G++AD R+ R E N++Y + S+ P+ +L + Q + Q
Sbjct: 64 AFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQF 123
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
A RP G +++ YD + GP +Y+T PSG +KA A G ++ YLE+ +
Sbjct: 124 AGKRPFGVGLLIAGYDRQ-GPRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGFPA 182
Query: 215 LSTDDAIQLAISCLSQVLS--VDFKSSEIEIGVVSKDNPKFRVLTETEIDRHL 63
D+ + A+ L S V+ I +V K P F +LTE E ++L
Sbjct: 183 CDLDELVMHALRALGAATSGGVELNIKNTTIAIVGKGTP-FTILTEEEARKYL 234
>UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like,
putative; n=5; Oligohymenophorea|Rep: Proteasome subunit
alpha type 7-like, putative - Tetrahymena thermophila
SB210
Length = 242
Score = 118 bits (284), Expect = 2e-25
Identities = 69/211 (32%), Positives = 114/211 (54%), Gaps = 2/211 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D IT+F G L+QVEYA+ A+NQG L S+ +RGTD V+ ++ L + ++
Sbjct: 3 YDTAITVFGKIGNLFQVEYAMAAVNQG-LCSIGIRGTDCIVMGVEKNPTTILQETRTIRK 61
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ L D +G+ D+R A+ E ++ Y +P++ + R IA + Q YTQ
Sbjct: 62 VQRLDDATCICYSGLTPDARILTNIAKVECQSYSLNYDDRVPINYIARYIASVQQKYTQK 121
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAG--AKTVDGNAYLEKKLKKR 222
+ RP G S ++ +D + P +++TDPSG +KAVA G KTV N LEK ++
Sbjct: 122 SGARPFGISTLVGGFDSKGQPRLFQTDPSGACTEWKAVALGKHRKTVMEN--LEKNYQEE 179
Query: 221 SDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 129
L+ + ++LA L +V+ K+ E+ +
Sbjct: 180 Y-LAEEKCLELACRVLLEVVQSGCKNIELVV 209
>UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2;
Trichomonas vaginalis|Rep: Proteasome subunit alpha type
- Trichomonas vaginalis G3
Length = 251
Score = 117 bits (282), Expect = 3e-25
Identities = 69/238 (28%), Positives = 125/238 (52%), Gaps = 8/238 (3%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S + +DR++ FSP+GRL QVEYA++A+ G ++VA+ + + A ++++ +LL +
Sbjct: 4 SGSEYDRNVNTFSPDGRLLQVEYAIEAVKLGS-SAVAILCPEGVIFAVEKRLSSQLLIAS 62
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
SV ++A+ D +G VM G+ AD R+ V R EA N ++ + I + + + + D++
Sbjct: 63 SVEKVYAIDDHVGVVMAGLAADGRTMVEHMRVEAQNHRFSFDEPIGIKAVTQSVCDLALA 122
Query: 407 YTQ------NAEM-RPLGCSMMLIAYDDEAGPC-VYKTDPSGYYCSYKAVAAGAKTVDGN 252
+ + + +M RP G ++++ E G C ++ TDPSG Y +A A G +
Sbjct: 123 FGEGRRKKGDGQMSRPFGTALLVAGI--ENGKCHLFHTDPSGTYTECRARAIGGGSEGAE 180
Query: 251 AYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETE 78
A L K ++ +A LA+S L QV+ + +E+ KF + T +
Sbjct: 181 ALLRDLYK--DGMTLHEAEDLALSTLRQVIQEKLNENNVEVACARVSTGKFEIYTSEQ 236
>UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 288
Score = 116 bits (280), Expect = 6e-25
Identities = 70/239 (29%), Positives = 125/239 (52%), Gaps = 2/239 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D + +SP+GR++Q+EYA++A+ QG V R + V+A ++ RL
Sbjct: 35 YDTDVVTWSPQGRVFQIEYAMEAVKQGTAV-VGARNDEIVVLACIKRSTSRLAGYQK--K 91
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
L+ + + IG ++G+ AD++ R E N+ + Y S IP++ L R+ SQV TQ
Sbjct: 92 LYKIDNHIGVAVSGITADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQE 151
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G ++L + DE+GP +++T PSG Y ++A G+++ YLEK K+ ++
Sbjct: 152 YGRRPFGVGLLLAGF-DESGPHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKHFKEFAN 210
Query: 215 LSTDDAIQLAISCLSQVLS--VDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
S D I + L LS + +++ ++ + N + L E E ++L I ++
Sbjct: 211 CSKDQLILHTLRALRSSLSSEQEMNQENVDVAILGR-NDIYNELLEEEKIKYLQIINQE 268
>UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 116 bits (280), Expect = 6e-25
Identities = 70/231 (30%), Positives = 124/231 (53%), Gaps = 2/231 (0%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
S +D+ F+P+GRL QVEYA++AINQ G +++ + + ++A +++ LL+ +
Sbjct: 2 SRRYDQKTNTFTPDGRLKQVEYAIEAINQTG-SALGVLTNEGMILATEKQEVSHLLEHSK 60
Query: 584 VTH-LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ ++ + I V++G AD+ + AR AAN +Y++ I + L I D Q
Sbjct: 61 HSEKIYPIDRHIFSVVSGHTADANILINYAREAAANHRYQFQDNIALEQLIINICDYKQN 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
TQ RP G + + YD + G ++ TDPSG Y +KA A G + N+YL++ K
Sbjct: 121 KTQVGGQRPFGTAFLFAGYDKKNGFQLFSTDPSGNYAGWKATAIGKNNLAANSYLKQDYK 180
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDF-KSSEIEIGVVSKDNPKFRVLTETE 78
+ +L+ + + +AI L + + + S+IEI V+S+ + + T E
Sbjct: 181 E--NLTLEQGLDIAIKALVKTMDTSSPQPSKIEIVVISQQGKEVKSKTYNE 229
>UniRef50_P21242 Cluster: Proteasome component C1; n=18;
Eukaryota|Rep: Proteasome component C1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 288
Score = 116 bits (280), Expect = 6e-25
Identities = 69/213 (32%), Positives = 110/213 (51%), Gaps = 1/213 (0%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+D ++FSP+GR +QVEYA+KA+ + G TS+ ++ D V A ++ + +LL P
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAV-ENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ + IGCV +G+I D R V R R EAA+++ Y + IP+ R+ Q +T
Sbjct: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+RP G S + D+ G +Y +PSG Y YK A G A LEK +
Sbjct: 126 YNSVRPFGVS-TIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP 184
Query: 218 D-LSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 123
+ LS +A++ A + + D K + E+ +
Sbjct: 185 EGLSAREAVKQAAKII-YLAHEDNKEKDFELEI 216
>UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1
- Homo sapiens (Human)
Length = 263
Score = 116 bits (280), Expect = 6e-25
Identities = 65/239 (27%), Positives = 125/239 (52%), Gaps = 2/239 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +T++SP+GR++Q+EYA++A+ QG T V L+ AV+ A ++ L A
Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSAT-VGLKSKTHAVLVALKRAQSEL--AAHQKK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ + + IG + G+ AD+R R E + ++ + +PV L I +Q+ TQ
Sbjct: 63 ILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQR 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G +++ YDD GP +++T PS Y +A++ GA++ YLE+ + + +
Sbjct: 123 YGRRPYGVGLLIAGYDD-MGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFME 181
Query: 215 LSTDDAIQLAISCLSQVLSV--DFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
+ ++ ++ + L + L D + + IG+V KD +F + + ++ L + E+
Sbjct: 182 CNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKD-LEFTIYDDDDVSPFLEGLEER 239
>UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2;
Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome
endopeptidase complex - Halorubrum lacusprofundi ATCC
49239
Length = 268
Score = 115 bits (277), Expect = 1e-24
Identities = 68/221 (30%), Positives = 114/221 (51%)
Frame = -2
Query: 776 GSRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLL 597
G +DR ++FSP+GR+YQVEYA +A+++G SV +R D V A + L+
Sbjct: 3 GGNDQQAYDRGTSLFSPDGRIYQVEYAREAVSRGA-PSVGVRTADGVVFVAMSRPSSTLM 61
Query: 596 DPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADI 417
+ S+ L L D +G G +AD+R + AR ++ + +YG + V L + + D
Sbjct: 62 EAESIEKLHKLDDHLGTASAGHVADARQLIDLARRQSQGNRLRYGEPVGVETLTKFVTDH 121
Query: 416 SQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
Q TQ RP G + +LI D P ++ DPSG +KA G D +LE+
Sbjct: 122 IQENTQRGGTRPYGAA-LLIGGIDNGEPRLFAADPSGTPNEWKATVIGGGRSDIQGHLEE 180
Query: 236 KLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSK 114
+ +LS D ++LAI+ L+ +F+ +++ + V++
Sbjct: 181 NWTE--ELSLDAGVELAIAALA-AHDDEFEPTDLAVATVTE 218
>UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1;
Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit -
Trypanosoma brucei
Length = 237
Score = 115 bits (276), Expect = 2e-24
Identities = 78/238 (32%), Positives = 123/238 (51%), Gaps = 2/238 (0%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S +G D+ IFS +GR++QVEYA KA++ G T+VA D VVA ++ + R+L+
Sbjct: 2 SGSGHDQSTDIFSADGRVFQVEYACKAVDNGS-TAVAACCKDGVVVAVEKILTSRMLEEG 60
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
S + A+ + G + G++ D + V RAR EA N + + + I +L RI + V
Sbjct: 61 SNNRIHAVDRQAGICVCGVLPDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHV 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YT + RP GCS+++ +Y D+ GP +Y DPSG Y +A G LEK
Sbjct: 121 YTTHYAYRPFGCSVIIASYADD-GPQLYVADPSGAVAGYYGIALGKGKTVAKTELEK--L 177
Query: 227 KRSDLSTDDAIQLAISCLSQV--LSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLT 60
+ L+ +A++ + L +V S D K E+E+ V + + V E+ H T
Sbjct: 178 DFATLTCSEAVEKLTNILHEVHDKSKD-KIYEVEVAWVCDKSDRTFVHVPKEMVPHPT 234
>UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 233
Score = 113 bits (271), Expect = 7e-24
Identities = 75/232 (32%), Positives = 116/232 (50%), Gaps = 1/232 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D + T FSPEGR+ QVE A+KA+ QG + +V L+ AV+A P +
Sbjct: 6 YDENATTFSPEGRILQVENAMKAVQQG-MPTVGLKSKTHAVIAGVMHSPSEF--SSHQPK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + IG ++G+ AD R R E + + +G+EI V L +A SQ T
Sbjct: 63 IFKIDQHIGVAISGLTADGRGLCKFLRNECLHHTFCFGTEIRVADLADTVALQSQKKTSK 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G +++I + GP +++T PSG + Y A A G + YLE L + D
Sbjct: 123 VGKRPYGVGLLMIGAGVD-GPRLFETCPSGQHWEYNAQAIGRRAQAAKTYLETNLNEFPD 181
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNPKFRVLTETEIDRHL 63
+ D I+ A+ L+ S + S E I +GVV D P F +L E+ +++
Sbjct: 182 CTRDQLIRHALRALNDCKSRESDSLEAIALGVVGIDEP-FTILEGPELQKYI 232
>UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4;
Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN -
Encephalitozoon cuniculi
Length = 232
Score = 113 bits (271), Expect = 7e-24
Identities = 70/236 (29%), Positives = 127/236 (53%), Gaps = 5/236 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
F + + +S EGR++Q+EYA+KA+N G T++ +R + ++ +++K+ L +P SV
Sbjct: 4 FKQSVNTYSSEGRIHQIEYAMKAMNL-GTTTIGVRTKEFVILCSEKKILSTLQNPKSVVK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ + D I +G+ D+++ V R+R + + YG I V L + ++ +S + +
Sbjct: 63 HYKIYDHIVLGFSGISGDTKTIVKRSRDFCISHTHMYGENISVERLLKYLSSLSLRFGEE 122
Query: 395 AE-----MRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
E RP G S+++ +D E P +Y DPSG Y SYKA A G+ LE +
Sbjct: 123 DEAKMIFRRPFGVSLIIAGFDTE--PRLYSLDPSGSYISYKAKAIGSGHEVVEGILENEY 180
Query: 230 KKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHL 63
++ S L D +++ + LS+V+ +E+ VV+++ KF LT E+ +L
Sbjct: 181 EEYSGL--DQSLRKVLCTLSKVMKDKISKDNVEVVVVTQEESKF--LTPEEVSVYL 232
>UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8;
Eukaryota|Rep: Proteasome subunit alpha type -
Alexandrium fundyense (Dinoflagellate)
Length = 254
Score = 112 bits (269), Expect = 1e-23
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 2/214 (0%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
+ AG+D +T FSP+GR++QVEYA KA+ G T+VA+ D + A ++ + ++L
Sbjct: 4 TGAGYDLSVTTFSPDGRVFQVEYAQKAVENSG-TTVAICCKDGVIFAVEKFLLSKMLVQG 62
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ +F + G + G ADSR V RAR EA ++ Y EIP +L R+
Sbjct: 63 TNKRIFPVHRHAGMSIAGFSADSRQIVARARSEAHQYKNSYNEEIPPELLAERLGLFVHA 122
Query: 407 YTQNAEMRPLGCSMMLIAYD-DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
YT +RP GCS++L D D P ++ DP+G Y A G +EK L
Sbjct: 123 YTLYWSIRPFGCSVLLGCVDQDTKKPSLFCVDPAGMVFKYSGTAIGKGKQAAKTEIEKLL 182
Query: 230 KKRSD-LSTDDAIQLAISCLSQVLSVDFKSSEIE 132
++ L+ +A+ L +V K E+E
Sbjct: 183 ANGTESLTCAEALVHVAKILHKVHDEKDKDFELE 216
>UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 238
Score = 111 bits (268), Expect = 2e-23
Identities = 65/217 (29%), Positives = 114/217 (52%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR +T FS +GRL+Q+EYA A + G T +A++ V A +++ +L S +
Sbjct: 3 YDRALTRFSSDGRLFQIEYAAAAAHNG-TTVLAIQAPGIIVAAIEKRDMMKLQKQDSSNN 61
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ L I C TG+ AD+R V +A++EA +++ + IP+ + R IA + YTQ+
Sbjct: 62 MCLLDKHILCAFTGLPADARVLVEKAQFEAQSYRLTFEDAIPIENIARYIATVQLTYTQS 121
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+RP G + ++ +D P +Y+T PSG +KA G Y+EK +
Sbjct: 122 GGVRPFGVTTLICGFDPLDKPHIYETLPSGILSEWKARGIGRFGHPVQEYIEKYYV--DN 179
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNP 105
LS DD ++ I L ++ D + +E+ ++ ++P
Sbjct: 180 LSEDDVKRITIGSLREI--ADCRPKNMEVAIMKPNSP 214
>UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16;
Drosophila|Rep: Proteasome subunit alpha type-7-1B -
Drosophila melanogaster (Fruit fly)
Length = 252
Score = 111 bits (268), Expect = 2e-23
Identities = 63/210 (30%), Positives = 112/210 (53%), Gaps = 1/210 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR +TI+SP+G L QVEYA +A+ +G T + LR +A V+ +++ L + V
Sbjct: 5 YDRAVTIYSPDGHLLQVEYAQEAVRRGS-TVMGLRTNNAIVIGVEKRSVGDLQEERMVRK 63
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ L D + +G+ AD+R V RA+ EA + + + V + R IA + Q YTQ+
Sbjct: 64 ICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQS 123
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G S ++ +D++ P +++TDPSG + ++A G + Y+EK +
Sbjct: 124 NGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILT 183
Query: 215 LSTD-DAIQLAISCLSQVLSVDFKSSEIEI 129
++ + AI+ + L V S++ E+ +
Sbjct: 184 IADEAAAIKHIVRTLVSVSSLNHTQMEVAV 213
>UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia
intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia
ATCC 50803
Length = 250
Score = 109 bits (262), Expect = 9e-23
Identities = 68/239 (28%), Positives = 124/239 (51%), Gaps = 13/239 (5%)
Frame = -2
Query: 743 ITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFAL 564
+T FSP G L Q+ YAL A++ GG S+ ++ + V+ + + L+D +++ + +
Sbjct: 10 LTTFSPSGHLRQITYALAAVD-GGRLSIGIKCANGVVLMCHKAAENPLVDYPTISLVDNV 68
Query: 563 TDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMR 384
+ +G +G AD R+ + R + ++ +PV++L R IA Q YTQ +R
Sbjct: 69 SPSLGITYSGFSADFRNLLNLGRKSYEQYWNEFQESMPVNMLARDIASTMQEYTQRGGVR 128
Query: 383 PLGCSMMLIA------YDDEA-----GPCV-YKTDPSGYYCSYKAVAAGAKTVDGNAYLE 240
P GCS++L ++ EA P + Y+ D SG Y ++KA A G ++ +LE
Sbjct: 129 PFGCSVLLAGKSMATEHETEANGSRINPYILYQVDSSGSYYTWKACANGNQSSQARDFLE 188
Query: 239 KKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD-NPKFRVLTETEIDRH 66
K+ + +S D I + ++CL + + D +EIG++ + +FR+L EI+ +
Sbjct: 189 KRYNE--SVSISDGILIGLTCLHEYVDGDIDGKTVEIGIIGDETGGQFRLLAADEINTY 245
>UniRef50_A6R382 Cluster: Proteasome component C1; n=3;
Pezizomycotina|Rep: Proteasome component C1 -
Ajellomyces capsulatus NAm1
Length = 426
Score = 109 bits (262), Expect = 9e-23
Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 26/200 (13%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+D +IFSP+GR +QVEYA+KA+ GG TS+ +R D V+A ++ + +LL P +
Sbjct: 136 GYDLSNSIFSPDGRNFQVEYAVKAVENGG-TSIGIRCKDGVVLAVEKIISSKLLKPGANK 194
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ + IG V +G++ D R V RAR EA NW+ Y I H+L R+ +Q YT
Sbjct: 195 RIATVDRHIGIVSSGLLPDGRHFVSRARDEADNWRITYKGPISTHVLASRLGGYAQAYTL 254
Query: 398 NAEMRPLGCSMMLIAYDDE--------------------------AGPCVYKTDPSGYYC 297
+ +RP G + ++ +D E GP +Y +PSG Y
Sbjct: 255 YSSVRPFGVTSIIGGWDSELELPVDGEVGAGPKSGAGGKVASAKAGGPGLYMIEPSGLYW 314
Query: 296 SYKAVAAGAKTVDGNAYLEK 237
Y A G A LEK
Sbjct: 315 GYYGAATGKGRQAAKAELEK 334
>UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12;
Magnoliophyta|Rep: Proteasome subunit alpha type-3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 249
Score = 109 bits (261), Expect = 1e-22
Identities = 58/179 (32%), Positives = 94/179 (52%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S G+D +T FSP+GR++Q+EYA KA++ G T V ++ D V+ ++ + +++
Sbjct: 2 SSIGTGYDLSVTTFSPDGRVFQIEYAAKAVDNSG-TVVGIKCKDGIVMGVEKLIASKMML 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
P S + ++ G + G+ AD R V RA+ EA +++ YG +PV L R+A
Sbjct: 61 PGSNRRIHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYV 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
+ T +RP GC ++L YD + GP +Y +PSG Y A G +EK
Sbjct: 121 HLCTLYWWLRPFGCGVILGGYDRD-GPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEK 178
>UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Aspergillus terreus (strain NIH 2624)
Length = 311
Score = 108 bits (260), Expect = 2e-22
Identities = 59/172 (34%), Positives = 93/172 (54%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G+D ++FSP+GR +QVEYA+KA+ GG T++ +R D V+A ++ + +LL P +
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGG-TAIGIRCKDGVVLAVEKIITSKLLKPGANK 65
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ + +G V +G++ D R V RAR EA++W+ Y S IPV L R+ Q YT
Sbjct: 66 RIATVDRHVGIVSSGLVPDGRHFVSRARDEASSWRGVYKSPIPVSALSNRLGSYVQAYTL 125
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYL 243
+ +RP G + ++ +D EA V SG GAK+ Y+
Sbjct: 126 YSSVRPFGITAIIGGWDSEAELAVDGQVGSGPTSGAGGKVEGAKSGGPGLYM 177
>UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative;
n=2; Theileria|Rep: Proteasome subunit alpha type 1,
putative - Theileria parva
Length = 252
Score = 107 bits (257), Expect = 4e-22
Identities = 65/219 (29%), Positives = 109/219 (49%), Gaps = 2/219 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +SP+GRL+QVEYA++++ QG T + A +RK+ +L
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMESVKQGTCCVGIKSNTHLVLCALKRKI-SKLAQVQD--K 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
L+ + + IG M+G+ +D++ + R E + ++ YG +I L +++ SQ TQ
Sbjct: 63 LYKVGEYIGVAMSGITSDAKMIISYMRNECLSNRFLYGCDITASQLVSLVSEKSQANTQV 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G +++ YD+ G +++T PSG + A A GA+ YLE+K+ S+
Sbjct: 123 SSKRPFGVGLLVAGYDETTGLHLFETCPSGNVVEFNATAFGARCQSAKTYLERKIVNFSE 182
Query: 215 LSTDDAIQLAISCLSQVLSVD--FKSSEIEIGVVSKDNP 105
+ I AI L + D F I +GVV K P
Sbjct: 183 SDLNGLIYHAIKALKTTIPNDGEFDVDVISVGVVGKGTP 221
>UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep:
Yarrowia lipolytica chromosome C of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 289
Score = 107 bits (257), Expect = 4e-22
Identities = 73/229 (31%), Positives = 110/229 (48%), Gaps = 2/229 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +SP GRL+QVEYAL+AI QG + T A VVA +R + +
Sbjct: 5 YDNDSVTYSPTGRLFQVEYALEAIKQGSAVVGLVSKTHAVVVALKRNAEEL---GSYQKK 61
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ + + +G + G+ D+R R +A + Q Y + V IAD +Q TQ
Sbjct: 62 IIKVDNHLGVALAGLAPDARVLSNFLRQQAMSSQMVYKRPLAVSRAVYAIADKAQGNTQQ 121
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G +++I + DEAGP +Y+ PSG Y+ A GA++ YLEKK D
Sbjct: 122 YGRRPYGVGLLIIGH-DEAGPHLYEFLPSGSALEYRGAAIGARSQAARTYLEKKFDTFPD 180
Query: 215 LSTDDAIQLAISCLSQVLSVD--FKSSEIEIGVVSKDNPKFRVLTETEI 75
LS ++ I ++ L L+ D I V KD P F +L + ++
Sbjct: 181 LSLEELIVEGLNALRDTLAQDKELTLKNTSIAYVGKDTP-FTLLDDDKV 228
>UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT
C6 - Encephalitozoon cuniculi
Length = 234
Score = 105 bits (253), Expect = 1e-21
Identities = 69/231 (29%), Positives = 114/231 (49%)
Frame = -2
Query: 737 IFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTD 558
IF+ +G+L Q+EY L+A+N G L V + D +V +K+P L+ + T +++
Sbjct: 10 IFNSDGKLLQIEYGLEAVNNG-LPVVTAKSKDM-IVCVSKKIPQDKLEESEATSFHRVSE 67
Query: 557 RIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPL 378
+ +TG+ D+ V R + A + +G E+ ILCR AD Q Q++ R
Sbjct: 68 KCYVAITGLPGDTDYVVKRIKMVANRKAFSFGFEVTPDILCRSFADKVQQLIQSSAERSA 127
Query: 377 GCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDA 198
+ + +D E P +Y+TD SG A AAG K ++EK RSD+ +
Sbjct: 128 AFNASIFGFDKER-PMIYQTDMSGISYPCYATAAGEKHGKMTKFIEKNY--RSDIDDKEL 184
Query: 197 IQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
++A+ L + + D SE+E+ + K L+ E+D+ L IAEK
Sbjct: 185 FEVAVGALLESIGADSGCSEVEVAYL-KVGQDLCHLSAKEVDKILQDIAEK 234
>UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative;
n=5; Plasmodium|Rep: Proteosome subunit alpha type 1,
putative - Plasmodium vivax
Length = 269
Score = 103 bits (248), Expect = 4e-21
Identities = 70/239 (29%), Positives = 116/239 (48%), Gaps = 2/239 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D +SPEGRLYQVEYA +AI QG +VA++ D VV +K +L
Sbjct: 6 YDTDNITYSPEGRLYQVEYANEAIKQG-TCAVAIKSKDFVVVCGLKKRISKL--SFHQEK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
LF + D IG M+G+ +D++ R E + ++ + + + L +++AD Q TQ
Sbjct: 63 LFKIDDYIGVTMSGITSDAKVLTKYMRNECLSHKFLFDENMNIEKLVKKVADKYQQNTQR 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ R G +++ Y E P +++T P+G Y Y A++ GA++ YLEK + D
Sbjct: 123 SSRRAFGVGLIIAGYFKE--PYIFETKPNGSYFEYIALSFGARSHASKTYLEKNVHLFED 180
Query: 215 LSTDDAIQLAISCLSQVLSV--DFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEK 45
S ++ + L LS + I +V KD P + T ++ + AE+
Sbjct: 181 SSLEELTIHCLKALRCSLSSENELTIENTSIAIVGKDKPWQEITTVDLVELLIRVNAEQ 239
>UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3;
Basidiomycota|Rep: Proteasome subunit alpha type -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 299
Score = 103 bits (247), Expect = 6e-21
Identities = 65/211 (30%), Positives = 101/211 (47%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D T FSP+G+L+QVEYAL+A+ QG ++ LR AV+ ++ L
Sbjct: 6 YDSDNTTFSPQGKLFQVEYALEAVKQGS-AAIGLRSNTHAVLLTLKRSTGELATYQK--K 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
L + D +G + G+ +D+R R +A + YG PV L + IAD +Q TQ
Sbjct: 63 LIRIDDHVGVAIAGLTSDARVLSNYMRQKAMQSRMTYGRATPVARLVQSIADRAQTNTQE 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G ++I DE GP +++ P+G Y A + GA++ YLEK +
Sbjct: 123 YGRRPYGVGFLVIG-KDETGPHLFEFSPAGTAFEYYAHSIGARSQSAKTYLEKNYHLFPN 181
Query: 215 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 123
S ++ I +S L L D S + +
Sbjct: 182 ASLEELINHGLSALHDTLQQDKHLSSLNTSI 212
>UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT
C3 - Encephalitozoon cuniculi
Length = 233
Score = 102 bits (245), Expect = 1e-20
Identities = 68/237 (28%), Positives = 116/237 (48%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
G ++ +T+FS EG+L Q + AL+A G L S+ D AV+ + + VP L+ V
Sbjct: 4 GREKPVTLFSSEGKLGQCDNALRAAVNGSL-SIGASAADGAVLMSFKDVPP-LVIREEVR 61
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+F + D IGC +G+ D R QV A + YG V + + + Q YTQ
Sbjct: 62 KVFKICDTIGCTYSGLQPDCRIQVNIGCQIAEEYYDVYGRYPDVDVFTAHFSSVVQEYTQ 121
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
+ RP G ++M+ A P +Y+ DPSG Y + A+G D ++E++L+
Sbjct: 122 KSGYRPFG-TLMIFAGPVRGVPRLYQVDPSGSYQTADVCASGVGYSDARKFVERRLE--- 177
Query: 218 DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
DD I +S + + + ++ +++IGV K F+ T EI+ ++++
Sbjct: 178 --GLDDNIVNCVSSIREFAGKEVRAKDLDIGVYYKTENIFKAFTLDEIEEVFDSLSK 232
>UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus lucimarinus CCE9901
Length = 236
Score = 102 bits (244), Expect = 1e-20
Identities = 61/214 (28%), Positives = 107/214 (50%), Gaps = 2/214 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D+ + +SP+GRL+QVEYA++A+ QG T VA AV+AA ++ +L +
Sbjct: 6 YDQDMLTWSPQGRLHQVEYAMEAVKQGS-TVVACGNKKCAVLAALKRKQSKL--SSMQEK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+FA+ R+G ++G+ D V R E+ ++ YG L + Q+ +
Sbjct: 63 IFAINTRVGVAVSGLSTDGAKLVKLLREESTREEFVYGRSACPGRLAAAASKSLQISMRK 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
+ RP G ++L+ ++ G +++T PSG A G ++ YLEK ++
Sbjct: 123 SSGRPCGVGLVLVGSSEQLGCQIFQTCPSGEVHQMSCTAIGGRSQSARTYLEKNMEALET 182
Query: 215 LSTDDAIQLAISCL--SQVLSVDFKSSEIEIGVV 120
S D+ I +A+ L S V + D S + E+ +V
Sbjct: 183 ASVDEMIMIALRALNESNVDASDLTSDKCEVAIV 216
>UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 247
Score = 99 bits (238), Expect = 7e-20
Identities = 51/167 (30%), Positives = 92/167 (55%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S +G+D T FSP+G+++Q++YA KA+ + T+++++ D V ++ + ++++
Sbjct: 2 SSIGSGYDDSCTTFSPDGKVFQIDYATKAV-ENSATALSIKCIDGVVFGVEKLIISKMIE 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
+S +F + +G G + D+R V +A EA +++ YG IPV +L +IA
Sbjct: 61 KSSNKRIFNVGTHVGITCAGFLPDARKLVKKANEEAESFKENYGMNIPVKVLAEKIAMYM 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAG 273
Q +T +RP GCS +LI D+ G ++ +PSG Y A G
Sbjct: 121 QNHTLYGSLRPFGCS-LLIGGVDQHGYSLHYIEPSGTTYGYFANGIG 166
>UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2;
Caenorhabditis|Rep: Proteasome subunit alpha type-3 -
Caenorhabditis elegans
Length = 250
Score = 99.5 bits (237), Expect = 9e-20
Identities = 69/247 (27%), Positives = 117/247 (47%), Gaps = 3/247 (1%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S G+D + FSP+GR++QVEYA KA++ G T +A+RG + VV A + + +L
Sbjct: 2 SSIGTGYDLAASTFSPDGRIFQVEYAQKAVDNAG-TMIAIRGKNGVVVVADKLISSKLYT 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
+ +F + D +G + G D + A EA W Y +P+ + +A+
Sbjct: 61 DNANPRMFNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYI 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
++T RP G ++++ + G ++ +PSG YKA A G A +EK
Sbjct: 121 HIHTLGIS-RPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEK- 178
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSKD-NPKF-RVLTETEIDRHL 63
K +L + ++ A + V + K+ +IE+G V + N K+ V +E
Sbjct: 179 -LKIEELDVNQLVKEAARIIMVVRDENKDKNVQIEMGWVGEQTNGKYEEVPSEVVTAAEE 237
Query: 62 TAIAEKD 42
AIA+ D
Sbjct: 238 WAIAKLD 244
>UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family
protein; n=5; Oligohymenophorea|Rep: Proteasome A-type
and B-type family protein - Tetrahymena thermophila
SB210
Length = 267
Score = 99.1 bits (236), Expect = 1e-19
Identities = 63/186 (33%), Positives = 101/186 (54%), Gaps = 3/186 (1%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D + +S G+L QV+YA KAI+QG +T + LR AV+ AQ++ +L
Sbjct: 23 YDTDCSTWSTNGKLLQVDYATKAIDQGSIT-IGLRSQKFAVLVAQKRSNSKL--SGYQEK 79
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+F + D+IG + G+ AD+R R E N +Y YGS+ P L +I++ SQ TQ
Sbjct: 80 IFQVDDKIGMGVAGITADARVICKYMRTECLNHKYVYGSQHPAQRLVIKISEKSQHKTQT 139
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL---KK 225
RP G ++IA + + GP +++T PSG + + + G+++ YLE L K
Sbjct: 140 YGKRPYGVGTLIIAQESD-GPKLFQTLPSGDFYEFYGQSIGSRSQAAKTYLENNLELFKD 198
Query: 224 RSDLST 207
+DL+T
Sbjct: 199 CNDLNT 204
>UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative;
n=6; Plasmodium|Rep: 20S proteasome alpha subunit G,
putative - Plasmodium vivax
Length = 253
Score = 97.9 bits (233), Expect = 3e-19
Identities = 53/186 (28%), Positives = 98/186 (52%), Gaps = 2/186 (1%)
Frame = -2
Query: 764 SAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRK--VPDRLLDP 591
SAG+D ++ FSP+GRLYQVEY KAIN T+++L D + + ++++
Sbjct: 5 SAGYDLSVSTFSPDGRLYQVEYIYKAINSNN-TALSLECKDGLLTCCVNSNLLKNKMIKH 63
Query: 590 ASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQ 411
+S + + + + + G+ D+R+ + RA+YEA ++ + + IP+HIL R++
Sbjct: 64 SSYSRIHHINNNVIVTYAGLDGDARNIIDRAKYEANSYYLNFHTNIPLHILANRVSLYLH 123
Query: 410 VYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL 231
+T +RP S++L ++D++ +Y +P+G Y V G +EK+
Sbjct: 124 SFTLYWHLRPFASSIILASFDEKEKGEIYCVEPNGACYKYSGVVIGKNKEMFKTEIEKRN 183
Query: 230 KKRSDL 213
K D+
Sbjct: 184 YKDVDV 189
>UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus tauri
Length = 262
Score = 96.7 bits (230), Expect = 7e-19
Identities = 59/190 (31%), Positives = 98/190 (51%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
+G+D T +SP+GR++QVEYA KA++ GGLT V ++ D V+A ++ VP +L P +
Sbjct: 66 SGYDLSTTTYSPDGRVFQVEYAGKAVDAGGLT-VGVKCVDGVVIACEKLVPSKLHKPGTN 124
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
A+ G +G D + RAR E AN++ YG IP +L R+A ++T
Sbjct: 125 RRTRAVARHAGVGGSGYTPDLAAVADRARAECANYKSFYGDAIPGKVLAERMAHYYHLFT 184
Query: 401 QNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR 222
+RP GCS +L D + G +Y + +G + G +EK K
Sbjct: 185 LYWSVRPFGCSTLLGCKDFD-GYHLYLVEQNGECAKMRGACIGKGKNAAKTEVEK--LKL 241
Query: 221 SDLSTDDAIQ 192
++++ +A++
Sbjct: 242 NEITCAEAVK 251
>UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1;
Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit,
putative - Trypanosoma cruzi
Length = 179
Score = 95.9 bits (228), Expect = 1e-18
Identities = 54/178 (30%), Positives = 94/178 (52%)
Frame = -2
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+V +F L D +GC +G+ D R V AR ++ Y +PV L R+I+ + Q
Sbjct: 7 TVQKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEPMPVSQLVRQISSLYQE 66
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
+TQ+ +RP GCS +L+A D G +Y+ DPSG + ++KA + G + D +LEK+
Sbjct: 67 FTQSGGVRPFGCS-LLVAGADSQGNHLYQVDPSGTFWAWKATSIGKGSTDAKTFLEKRY- 124
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+++ +DA+ A+ L + + ++G VS+ KF + T ++ +L I
Sbjct: 125 -TNEMEIEDAVHTALLTLKEGFDGTMTAENTQVGRVSEG--KFELFTVDQLKDYLDQI 179
>UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Chaetomium globosum (Soil fungus)
Length = 267
Score = 95.9 bits (228), Expect = 1e-18
Identities = 56/201 (27%), Positives = 97/201 (48%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D FSP+GR++QVEYA +A+ QG + T +VA +R + +
Sbjct: 6 YDNDSVTFSPQGRIFQVEYAAEAVKQGSVVVGIASKTHVVLVAIKRNAEEL---SSYQKK 62
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
LF + + +G + G+ +D+R + + + +G +PV L I +Q+ TQ+
Sbjct: 63 LFPIDEHVGIAIAGLTSDARVLSNFMKQQCLGHRLTFGRSMPVRTLVEIIGSKAQINTQH 122
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G +++ DD GP +++ PSG A A GA++ YLEK + K +D
Sbjct: 123 YGKRPYGVGLLVAGVDDH-GPHLFEFQPSGMTEEMVAFAIGARSQMARTYLEKNIDKFAD 181
Query: 215 LSTDDAIQLAISCLSQVLSVD 153
++ I+ + L + L D
Sbjct: 182 CDREELIRHGLRALKESLVQD 202
>UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia
intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia
ATCC 50803
Length = 245
Score = 95.1 bits (226), Expect = 2e-18
Identities = 66/237 (27%), Positives = 114/237 (48%), Gaps = 6/237 (2%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
SS D H +FSP+GR++Q+EYALK++ T++A+R V A +R+ L
Sbjct: 2 SSNSHDTHANVFSPDGRIFQIEYALKSVTLSP-TALAIRTHTGIVFAVERRTSSPLRLQT 60
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ + D + G +DS+ + AR EA + ++ Y +P+ L ++++
Sbjct: 61 RFERIMHVDDHAMACVAGHASDSKLLLQSARTEAQSHRFLYDEFVPLQALSESLSEVFIN 120
Query: 407 YTQNAEM--RPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
+ + + RP GCS +LI D + P ++ +PSG A + GA + L+
Sbjct: 121 FGRGKKKLGRPFGCS-LLIGGLDGSTPRLFCAEPSGSVTEAMARSLGAGSTTAQQTLQDS 179
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD----NPKFRVLTETEI 75
R D++ DDA LA+ L V+ + +E+ +S D P +L+E EI
Sbjct: 180 Y--RDDMTLDDAKLLALEILRDVMESTVRGDNVEMATISYDPVNKAPVKSLLSEEEI 234
>UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia
intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia
ATCC 50803
Length = 292
Score = 94.3 bits (224), Expect = 3e-18
Identities = 59/187 (31%), Positives = 93/187 (49%), Gaps = 10/187 (5%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
+G+D +SP+G+++QV+YALKA+ Q GL V +R + +A Q+ + D +L+ S
Sbjct: 26 SGYDVSCGSYSPDGKIFQVDYALKAVEQHGLC-VGIRTSGGVALAVQKNIHD-ILEIDSA 83
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYT 402
+ + D I + G+ D V +AR A +++ Y +P +L I+ Q+YT
Sbjct: 84 PCFYQIEDSIVIAVAGLQPDGMVLVSKAREVAESYRENYSRIVPTGVLANSISGYMQLYT 143
Query: 401 QNAEMRPLGCSMMLIAYDDEAG---PCVYKT-------DPSGYYCSYKAVAAGAKTVDGN 252
E+RP GCS+++ YD A P KT PSG + A AAG T
Sbjct: 144 HYGEVRPFGCSLLIAGYDSIASADEPTTLKTKYSLYLLQPSGDITNCFATAAGRHTSQAK 203
Query: 251 AYLEKKL 231
LE +
Sbjct: 204 VELENHM 210
>UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 244
Score = 93.9 bits (223), Expect = 5e-18
Identities = 56/195 (28%), Positives = 100/195 (51%)
Frame = -2
Query: 752 DRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHL 573
D +T F+ +G + QVEYA KA++ T + +R D ++ A++K+ +L+ S +
Sbjct: 3 DLSVTTFTQDGYIKQVEYAQKAVSDSE-TILGVRCKDGVILGAEKKLQTKLMVEDSDRRI 61
Query: 572 FALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNA 393
+ + IG ++ G I D R+ V RAR EA ++ + I IL R +T
Sbjct: 62 YNIQKNIGMIVGGRIPDGRNVVHRARKEAQEYEKYFSMPISGRILSERTGQYLHAHTLYG 121
Query: 392 EMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDL 213
RP GCS+++ +YD G ++++D +GY Y A A G + A+ + + DL
Sbjct: 122 AYRPFGCSVIISSYDPIDGLQLHQSDNAGYCLGYYACAQGQGKQEVMAHFGR--RNFRDL 179
Query: 212 STDDAIQLAISCLSQ 168
+ ++A+ I L++
Sbjct: 180 TCEEALPYVILALNK 194
>UniRef50_Q9BZ93 Cluster: Prosomal P27K protein; n=6; Eutheria|Rep:
Prosomal P27K protein - Homo sapiens (Human)
Length = 58
Score = 93.1 bits (221), Expect = 8e-18
Identities = 41/57 (71%), Positives = 49/57 (85%)
Frame = -2
Query: 701 YALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGM 531
YA KAINQGGLTSVA+RG D AV+ Q+KVPD+LLD ++VTHLF +T+ IGCVMTGM
Sbjct: 1 YAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGM 57
>UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 240
Score = 92.7 bits (220), Expect = 1e-17
Identities = 60/215 (27%), Positives = 105/215 (48%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S + +G+D + FSP+GR +QVEYA KA+ + L ++ ++ D ++AA++ + LL
Sbjct: 2 SGAGSGYDFNPITFSPDGRQFQVEYATKAVEKDSL-ALGVKCKDGILLAAEKNLTSTLLT 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
P +F + D I C G D S V ++R A + +G +I V L ++
Sbjct: 61 PGGNPRIFWINDSIACATIGHRPDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQQF 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
+ RP GC+++ +Y D+A +Y +PSG + Y A G + A L+K
Sbjct: 121 HLAHYYQAYRPFGCTVIFASYKDDA---LYAIEPSGAFYGYFASCFGKNSNLARAELQKT 177
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 129
K +++ +A+ + + FK EIE+
Sbjct: 178 EWK--NITVREAVPEVARIIKSLHESQFKKWEIEM 210
>UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia
intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia
ATCC 50803
Length = 255
Score = 91.5 bits (217), Expect = 2e-17
Identities = 69/237 (29%), Positives = 117/237 (49%), Gaps = 6/237 (2%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D + FSP G+L Q+ YA++A + G SV L DA V+ A R+ L +
Sbjct: 3 YDSDVATFSPTGKLNQITYAMEAPSFGS-PSVGLASKDAVVLVAVRRQTTPL--SSFQDK 59
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
LF + IG ++G+ AD+ + R E + Y Y + PV L ++A+ +Q TQ
Sbjct: 60 LFEVDKHIGICISGIYADAYKMLRLLRDECTEYTYVYDTPHPVGPLVAKLAEDAQARTQF 119
Query: 395 AEMRPLGCSMMLIAYD---DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKK 225
RP G S+++ D ++ P +Y P+ + Y+AV+ G + N +L+ + +
Sbjct: 120 WGYRPYGASLLIGGIDTRNNKQTPRLYVLSPNAVFKEYRAVSLGMGSQTINTHLKSHVDE 179
Query: 224 RSDLSTDDAIQLAISCLSQVLSVDFKSSE--IEIGVVSK-DNPKFRVLTETEIDRHL 63
+ S + I LA+ L + D + SE + IGV+ + R+LT+ EI H+
Sbjct: 180 YENASVERLIALALDSLGTGVK-DCRPSEKNLSIGVLDRTTGGVLRILTKEEILPHI 235
>UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 91.1 bits (216), Expect = 3e-17
Identities = 55/214 (25%), Positives = 111/214 (51%), Gaps = 2/214 (0%)
Frame = -2
Query: 767 SSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPA 588
S + +D + +S EGR+YQVEYA KA+ + T + ++ D ++A +++ RLL+
Sbjct: 2 SGSMYDLSVATYSQEGRIYQVEYATKAV-ENSETVIGVKCKDGVILAGEKQKFSRLLEDN 60
Query: 587 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 408
+ ++ + + G + G + D R+ + RA+ E++ +Q Y + ++L R+A
Sbjct: 61 TNKRIYNIDTQTGMAICGKLPDGRNILQRAKAESSQYQDMYAIPVSANVLSDRVAQYVHA 120
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YT + RP G + + +Y+ G ++ +PSG +Y A G G A + + +
Sbjct: 121 YTMYSGARPFGSATFIASYNTFDGYELFMIEPSGNKYAYHACTHG----KGRAVCKSEFE 176
Query: 227 KRS--DLSTDDAIQLAISCLSQVLSVDFKSSEIE 132
+R+ DL+ +A+ + I+ + + +FK + E
Sbjct: 177 RRNFKDLTCQEAL-VYIAKMLILAHEEFKEKKYE 209
>UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 306
Score = 90.2 bits (214), Expect = 6e-17
Identities = 65/219 (29%), Positives = 106/219 (48%), Gaps = 2/219 (0%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+D FSP GRL+QVEYAL+AI QG T V LR V+ A ++ D L +
Sbjct: 79 YDGDTVTFSPTGRLFQVEYALEAIKQGSAT-VGLRSNKYVVLVALKRNADEL--SSYQKK 135
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 396
+ D +G + G+ D+R R + Q Y ++ V + ++D +Q TQ+
Sbjct: 136 IIKCDDHMGLSLAGLAPDARVLSNFLRQQCNYSQLVYARDLSVVKAGQLLSDKAQKNTQS 195
Query: 395 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 216
RP G ++L YD+ +G + + PSG A GA++ YLE+ +++ +
Sbjct: 196 YGGRPYGVGLLLAGYDN-SGAHLLEFQPSGNTLELYGAAIGARSQGAKTYLERVMEEYLE 254
Query: 215 LSTDDA-IQLAISCLSQVLSVDFKSSE-IEIGVVSKDNP 105
+ DA I+ + L L + S++ + I +V KD P
Sbjct: 255 IEDADALIKHGVEALKHSLKDETLSTKNLSIAIVGKDMP 293
>UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis
vinifera|Rep: Proteasome subunit alpha type - Vitis
vinifera (Grape)
Length = 219
Score = 83.8 bits (198), Expect = 5e-15
Identities = 44/117 (37%), Positives = 67/117 (57%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASV 582
A +DR IT+FSP+G L+QVEYAL+A+ +G +V +RGTD V+ ++K +L D +V
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGN-AAVGVRGTDTIVLGVEKKSTAKLQDSRTV 60
Query: 581 THLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQ 411
+ L D I G+ AD+R + RAR E + + + V + R IA + Q
Sbjct: 61 RKIVNLDDHIALACAGLKADARVLINRARIECQSHRLTVEDPVTVEYITRYIAGLQQ 117
>UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative;
n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3,
putative - Theileria parva
Length = 267
Score = 83.4 bits (197), Expect = 7e-15
Identities = 69/253 (27%), Positives = 119/253 (47%), Gaps = 23/253 (9%)
Frame = -2
Query: 761 AGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAA-------QRKVP-D 606
AG+D ++ FSP+GR++QVEYA KA++ T+VA +D V AA Q P
Sbjct: 6 AGYDLSVSTFSPDGRVFQVEYATKAVDSAP-TAVAAVFSDGIVFAADSLACGAQDDSPYA 64
Query: 605 RLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRI 426
+L +FA+ +R+G + G++ D++ V RA+ E ++ +YG++ PV ++ R+
Sbjct: 65 NVLQAKPAWRVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKEYGTKAPVRVIAERV 124
Query: 425 ADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT------------DPSGYYCSYKAV 282
A YT +RP G S++L ++ Y + SG Y +
Sbjct: 125 ALFVHAYTLYWHVRPFGVSILLAGTNENNSRTTYSVLQLFTSYELYCIEGSGACYKYGGM 184
Query: 281 AAGAKTVDGNAYLEK-KLK-KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD- 111
A G LEK LK K+ S D + C + K+S++++ + D
Sbjct: 185 AIGKGKHIAKTELEKLNLKEKKCKESLSDICYIISQCRDE---GSLKTSDVQMAWICPDS 241
Query: 110 NPKFRVLTETEID 72
N F+++ + I+
Sbjct: 242 NNTFQIIPQELIN 254
>UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1;
Rattus norvegicus|Rep: Putative uncharacterized protein
- Rattus norvegicus (Rat)
Length = 99
Score = 83.0 bits (196), Expect = 9e-15
Identities = 46/102 (45%), Positives = 60/102 (58%)
Frame = -2
Query: 542 MTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 363
M G+ ADSR QV RA YEAANW+ K G E PV +LC+RI D+SQVYTQ+ E+R L C M+
Sbjct: 1 MVGITADSRFQVPRAHYEAANWKDKCGYEFPVGVLCKRIDDVSQVYTQDNEVRLL-CCMI 59
Query: 362 LIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 237
+ Y+ + P + C A A K ++LEK
Sbjct: 60 CMGYELKTRPSSVQVGS----CRLYATTAEVKQTQPTSFLEK 97
>UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome
(prosome, macropain) subunit, alpha type, 8 isoform 2;
n=1; Macaca mulatta|Rep: PREDICTED: similar to
proteasome (prosome, macropain) subunit, alpha type, 8
isoform 2 - Macaca mulatta
Length = 261
Score = 81.8 bits (193), Expect = 2e-14
Identities = 42/115 (36%), Positives = 67/115 (58%)
Frame = -2
Query: 755 FDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH 576
+DR IT+FSP+G L+QVEYA +A+ +G T+V +RGT+ V+ ++K +L D +V
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGTNIVVLGVEKKSVAKLQDERTVRK 63
Query: 575 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQ 411
+ AL D + G+ AD+R + RAR E + + + V + R IA + Q
Sbjct: 64 ICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 118
>UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 266
Score = 79.8 bits (188), Expect = 8e-14
Identities = 39/125 (31%), Positives = 67/125 (53%)
Frame = -2
Query: 662 VALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAA 483
V +RG D V+ ++K +L + +V + L D + G+ AD+R + RAR E
Sbjct: 6 VGVRGKDLVVLGVEKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQ 65
Query: 482 NWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGY 303
+ + + V + R +A + Q YTQ+ RP G S +++ +D + P +Y+TDP+G
Sbjct: 66 SHRLTVEDPVTVEYITRFMAQLKQRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGT 125
Query: 302 YCSYK 288
Y S+K
Sbjct: 126 YHSWK 130
Score = 68.1 bits (159), Expect = 3e-10
Identities = 36/121 (29%), Positives = 67/121 (55%)
Frame = -2
Query: 407 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 228
YTQ+ RP G S +++ +D + P +Y+TDP+G Y S+KA A G +LEK
Sbjct: 132 YTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEKHYS 191
Query: 227 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAE 48
S + ++LA+ L +V+ K+ IE+ V+ + P ++ +E+++++T I +
Sbjct: 192 DEVVESESETVKLAVRALLEVVQSGAKN--IELAVMRRGEP-LKMYEVSEVEKYVTEIEK 248
Query: 47 K 45
+
Sbjct: 249 E 249
>UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia
theta|Rep: 26S proteasome SU A5 - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 79.4 bits (187), Expect = 1e-13
Identities = 65/231 (28%), Positives = 106/231 (45%), Gaps = 5/231 (2%)
Frame = -2
Query: 731 SPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRI 552
SPEGRL +EYA +A N G TS ++ D + ++RK + LD + ++ L
Sbjct: 8 SPEGRLKDLEYAQEAANLGS-TSCGIKTKDFIFILSERK-KKKSLDYLNDQKIYVLDKNK 65
Query: 551 GCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEM----- 387
GC ++G+I+DSR + R N + S + I ++ Y N ++
Sbjct: 66 GCCVSGLISDSRKIIDNVRIYCENKYFLINSYPSIEECSNLINNLITSYNTNNDVNKISP 125
Query: 386 RPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLST 207
RPLG S +L ++ + K DPSG Y K +A G + D L++ RS++
Sbjct: 126 RPLGTSFLLFGKSNKKLELI-KVDPSGRYIKDKILAIGEGSKDVLIILQEGY--RSNMKK 182
Query: 206 DDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI 54
+A LA L + +E +S+ N R+L + EI++ L I
Sbjct: 183 IEAKTLAFKTLRAISESILNEKNVEAAQISESN-TLRILFKEEINQILKLI 232
>UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4;
Saccharomycetales|Rep: Proteasome component Y7 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 178
Score = 76.2 bits (179), Expect = 1e-12
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 2/158 (1%)
Frame = -2
Query: 539 TGMIADSRSQV*RARYEA-ANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 363
+GM D R V +AR A N++ Y PV I+ + IA + Q TQ+ +RP G S++
Sbjct: 4 SGMGPDFRVLVDKARKLAQTNYKLIYNEYPPVRIMVQEIAKVMQESTQSGGIRPFGVSLL 63
Query: 362 LIAYDDEAGPC-VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLA 186
+ YD+ +Y+ DPSG Y +KA A G + +LEK+ + +L +DAI +A
Sbjct: 64 VGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEKRWNE--NLQLEDAIHVA 121
Query: 185 ISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 72
+ L + + + ++I V+S + T T ++
Sbjct: 122 LLALKESVDGELIGENLDIAVISDPQQQLLGFTGTNLE 159
>UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT
ALPHA-4 - Encephalitozoon cuniculi
Length = 224
Score = 75.4 bits (177), Expect = 2e-12
Identities = 58/202 (28%), Positives = 92/202 (45%)
Frame = -2
Query: 758 GFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVT 579
GF+ + +FSP+GRL QVEYA +A QG L + ++ V+ +RK +RLL
Sbjct: 2 GFEEQLAVFSPDGRLIQVEYAQQASEQGSLVVFGV-DSEKISVSIERKSGNRLLLEEEKL 60
Query: 578 HLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ 399
+ + +I +G D+ + AR +++ G +I + L R +++ Q YT
Sbjct: 61 FPISESQKIWMSYSGFKPDAYLVMNVARMICFSYKNSTGEDIAIDQLARMLSEYKQRYTV 120
Query: 398 NAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS 219
RP G +L E P Y +P G + + A G K+ YLEK K
Sbjct: 121 VYHQRPFGVRTVLFGL--EPRPVAYVLEPDGNFSEFFCGAIGQKSQKVCEYLEKGEK--- 175
Query: 218 DLSTDDAIQLAISCLSQVLSVD 153
D ++L I L +V+ D
Sbjct: 176 ----GDLVRLTILGLMEVVQSD 193
>UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1;
Guillardia theta|Rep: Similar to proteasome A-type
submit - Guillardia theta (Cryptomonas phi)
Length = 233
Score = 74.9 bits (176), Expect = 2e-12
Identities = 52/224 (23%), Positives = 112/224 (50%)
Frame = -2
Query: 746 HITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFA 567
+++ F+ +G++ Q+EYA KA+ Q T ++++G + + + + +F
Sbjct: 5 NLSSFNSKGKISQIEYASKAVLQSN-TVISVKGNNLLLTLTLDISNKKNIFTQIEPKVFI 63
Query: 566 LTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEM 387
+ I +G+ +D + +AR ++Q+KYG +I L + ++ Q +T ++
Sbjct: 64 INKYIILSASGLKSDIIIVISKARSICRDFQHKYGHQISTASLSKDLSSFLQNFTSSSGF 123
Query: 386 RPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLST 207
RPLG S+ ++ D + GP +++ + SG + G + D Y+ + + S+L T
Sbjct: 124 RPLGVSLNILGIDKD-GPELFEINTSGEINDVNFSSIGKSSKDIKEYI--RARWCSNLET 180
Query: 206 DDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEI 75
++L I+CL+ V K EI I ++ PK ++ ++ ++
Sbjct: 181 KTLLKLVINCLNYYNLVTSKLVEIVIATIN-TQPKIKIFSKEDL 223
>UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE
SUBUNIT C9 - Encephalitozoon cuniculi
Length = 232
Score = 73.3 bits (172), Expect = 7e-12
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 1/213 (0%)
Frame = -2
Query: 734 FSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDR 555
F+ EGRL QVE+A+K +++ G T + +D V+ K P + ++ L+D
Sbjct: 11 FTDEGRLPQVEFAIKNVSRAG-TIIGYVCSDGVVLMGVNKEPTN----GPMEKIYQLSDS 65
Query: 554 IGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLG 375
I CV+ G+ D+ AR +A ++G E P+ LC+ + Q +TQ A RP G
Sbjct: 66 IYCVLCGLFGDAMELKRYARIKAQEVLERFGVECPLTTLCKFVGQRKQAFTQYAGTRPFG 125
Query: 374 CSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAI 195
S + D + TDPSG +K + G N L+ + ++ A
Sbjct: 126 VSFLYAGVID-GKYALMSTDPSGTSNRWKGMCYGENEEAINRGLKNDFPE-DEMDMKTAT 183
Query: 194 QLAISCLSQVLSVDFKSSE-IEIGVVSKDNPKF 99
+ L + + K ++ +EI SKD K+
Sbjct: 184 VEILRLLGKARELGPKEADRLEILHFSKDCKKY 216
>UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1;
Homo sapiens|Rep: Proteasome alpha 6 subunit variant -
Homo sapiens (Human)
Length = 80
Score = 72.9 bits (171), Expect = 9e-12
Identities = 29/61 (47%), Positives = 44/61 (72%)
Frame = -2
Query: 368 MMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQL 189
M+LI D+E GP VYK DP+GYYC +KA AAG K + ++LEKK+KK+ D + + +++
Sbjct: 9 MILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVEV 68
Query: 188 A 186
+
Sbjct: 69 S 69
>UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA,
RIKEN full-length enriched library, clone:C920013M15
product:proteasome (prosome, macropain) subunit, alpha
type 3, full insert sequence; n=13; Euteleostomi|Rep: 2
days neonate thymus thymic cells cDNA, RIKEN full-length
enriched library, clone:C920013M15 product:proteasome
(prosome, macropain) subunit, alpha type 3, full insert
sequence - Mus musculus (Mouse)
Length = 180
Score = 68.1 bits (159), Expect = 3e-10
Identities = 45/144 (31%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Frame = -2
Query: 542 MTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 363
+ G++AD+RS AR EA+N++ +G IP+ L R+A YT + +RP GCS M
Sbjct: 3 VAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFM 62
Query: 362 LIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAI 183
L +Y G +Y DPSG Y A G +EK K +++ D ++
Sbjct: 63 LGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDVVKEVA 120
Query: 182 SCLSQVL-SVDFKSSEIEIGVVSK 114
+ V V K+ E+E+ V +
Sbjct: 121 KIIYIVHDEVKDKAFELELSWVGE 144
>UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia
theta|Rep: 26S proteasome IOTA SU - Guillardia theta
(Cryptomonas phi)
Length = 237
Score = 65.3 bits (152), Expect = 2e-09
Identities = 46/208 (22%), Positives = 92/208 (44%)
Frame = -2
Query: 734 FSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDR 555
F+P GR++Q+EYA+K + G + ++ + + ++ + + L D+
Sbjct: 10 FAPSGRIFQIEYAVK--KKKGSICIGIKNNSFLIFLLYKS--QNSSSESNESDIIFLDDK 65
Query: 554 IGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLG 375
GC+ G+ D Q+ + N+ +Y S+I L + I +Q T + RP
Sbjct: 66 TGCLCNGLAIDVYEQIEEIKNIFFNYYSQYRSKIQTSYLSKLITFKNQYLTHYSFSRPRS 125
Query: 374 CSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAI 195
++++ D+E G ++K D +G + + G K ++ YL KK K S + + ++
Sbjct: 126 TNLIIFNLDNELGGQLFKGDNTGSFILTNECSIGYKDIE-IEYLLKKKKPESFQNIEKSV 184
Query: 194 QLAISCLSQVLSVDFKSSEIEIGVVSKD 111
+ + L + + I I S D
Sbjct: 185 EKLLEVLITSIKDELVIENIRIFFTSGD 212
>UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia
theta|Rep: 26S proteasome SU - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 64.1 bits (149), Expect = 4e-09
Identities = 40/175 (22%), Positives = 84/175 (48%)
Frame = -2
Query: 737 IFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTD 558
++S +GR+ Q+E+AL+ I++ +++ + + A K + FAL
Sbjct: 5 LYSHDGRVEQLEFALELIDKSN-SAIGIIYEKGILFATMEKNKHNS-EKEYQNFTFALEK 62
Query: 557 RIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPL 378
I C+ +G I D+ + + + A ++ + +P+ + ++DI TQ RPL
Sbjct: 63 NIICIASGNIPDANTILFYLKSFADEYKLMFQETVPIEKIVGYLSDIMHKPTQMIYQRPL 122
Query: 377 GCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDL 213
G S ++ +D+ G ++K DPSG + ++A + G + +E+ + +L
Sbjct: 123 GVSFIIGGWDEFRGFQLFKIDPSGNFSGWRATSIGFNNILNQTLIEENYHNKINL 177
>UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia
theta|Rep: 26S proteasome SU alpha7 - Guillardia theta
(Cryptomonas phi)
Length = 241
Score = 64.1 bits (149), Expect = 4e-09
Identities = 55/225 (24%), Positives = 99/225 (44%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
S +G+D TIF+PEG+L Q+EY+ K IN+ + ++ ++ D ++ + D
Sbjct: 2 SSIKSGYDLLPTIFTPEGKLLQLEYSSKCINKSNI-ALGIKCNDGLIIFKEIDSNQYNND 60
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADIS 414
+F L + +G+ D RS R E +Y+YG E+ L ++ +
Sbjct: 61 IIECNMIFCLNHYMAMTSSGITGDFRSLCNRLVDENLIEKYRYGLELNSKYLTHLLSRLF 120
Query: 413 QVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 234
+ + + +RPL C ++L + D + ++ G ++ G+ N LE
Sbjct: 121 HLNSNSWSLRPLACDIIL-GFIDYSSLEIFFISNQGSIIKTNNISTGSACELINFELESI 179
Query: 233 LKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKF 99
K+ +LS I I LS L+ D +S + +K KF
Sbjct: 180 FKE--ELSCRKVILKIIKKLS-ALTRDLQSKYFYVKYFAKKKKKF 221
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/178 (24%), Positives = 87/178 (48%), Gaps = 1/178 (0%)
Frame = -2
Query: 668 TSVALRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 492
T + ++ + V+A ++++ D + + + +T +G G++ D++ + R
Sbjct: 19 TVLGIKAVNGVVIAGEKRLTYDGYVLSKNTRKVHPITKHVGIGFAGLVGDAQFIIRALRM 78
Query: 491 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 312
EA N++ + G EI V R +A I + + ++ PL +++ +D E GP +Y DP
Sbjct: 79 EAENYELQLGREIRV----RGLAKILSLILYSYKLAPLMTEVVVGGFD-EKGPQIYVLDP 133
Query: 311 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 138
G K VA G+ +EK+ R D+ D+A +LA+S + + + D S +
Sbjct: 134 VGSLIEDKYVALGSGGPIALGIIEKEY--REDIDVDEAEKLAVSAIREAIERDAVSGD 189
>UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 200
Score = 61.7 bits (143), Expect = 2e-08
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 2/195 (1%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVPDRLLDPASVT-HLFALTDRIGCVMTGMIADSRSQV*RA 498
G T+V L G D V+AA R+ T + + I + G + D++ V R
Sbjct: 12 GTTTVGLVGKDFVVLAADRRATAGYFIANKQTWKIVEIDSHIAATIAGTVGDAQQLVDRL 71
Query: 497 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 318
R EA ++ G +PV + +A ++ + + RP+ MLI D GP ++
Sbjct: 72 RVEARYYKTITGDSMPV----KSVATLASLIL--FQYRPILSVQMLIGGVDSDGPSLFSV 125
Query: 317 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 138
D G K A G+ + + LE + R DLS ++A+ LA+ ++ L+ D S E
Sbjct: 126 DWLGTVTREKYTATGSGSPYAVSLLEHEY--REDLSLEEAVNLAVKAVNIALARDPGSGE 183
Query: 137 -IEIGVVSKDNPKFR 96
++I ++K+ + +
Sbjct: 184 GVDIATITKEGIRMK 198
>UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1;
Medicago truncatula|Rep: 20S proteasome, A and B
subunits - Medicago truncatula (Barrel medic)
Length = 336
Score = 56.0 bits (129), Expect = 1e-06
Identities = 53/210 (25%), Positives = 101/210 (48%), Gaps = 7/210 (3%)
Frame = -2
Query: 680 QGGLTSVALRGTDAAVVAAQRKV--PDRLLDPASVTHLFALTDRIGCV-----MTGMIAD 522
Q G T++ L+ + V+AA++++ P L P V ++ + + I C+ +TG IA+
Sbjct: 134 QLGTTAIGLKFKEGVVLAAEKRITWPTSPLYPGIVQNIMEIDNNI-CIAVTVTVTGSIAN 192
Query: 521 SRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDE 342
+ V AR A + V +C++++ Y ++ P S LIA D
Sbjct: 193 ASKLVGEARTLALANNISRCQPMVVDSMCQKLS-----YELADQIHPFVVS--LIAGHDN 245
Query: 341 AGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL 162
P +Y +DP G + A A G ++ + LE++ + DL+ + A +A+S L QV+
Sbjct: 246 NRPSLYYSDPFGSFQQCNAKAIGLRSEGADRSLEEQFNQ--DLTLEKAETIALSILKQVM 303
Query: 161 SVDFKSSEIEIGVVSKDNPKFRVLTETEID 72
+ ++I V+ P + + T +E++
Sbjct: 304 GEKVTPNNVDIAKVA---PAYHLYTFSELE 330
>UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2;
Desulfurococcales|Rep: Proteasome beta subunit -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 204
Score = 54.8 bits (126), Expect = 3e-06
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 4/202 (1%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 498
G T+V +RG V+AA+++V + + ++ +TD +G + G+ AD ++
Sbjct: 8 GATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKIL 67
Query: 497 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 318
R E + G I V + R +A I Y + P ++ + + +Y
Sbjct: 68 RAEIEYYNIVTGRRISVRAVARLLATILYSY----KYYPFLSETLVGGLEADGTAKLYVM 123
Query: 317 DPSGYYCS--YKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKS 144
DP G Y A+ +GA G LE K D+S DDA +LAI+ + + D S
Sbjct: 124 DPLGSLIEDDYAAIGSGAPIAIG--ILENGYSK--DMSVDDAKKLAIAAVRAAIERDAMS 179
Query: 143 SE-IEIGVVSKDNPKFRVLTET 81
+ I++ V+ ++ + E+
Sbjct: 180 GDGIDLLVIRREEDSIKAEEES 201
>UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY
SUBUNIT 8 - Encephalitozoon cuniculi
Length = 242
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/211 (23%), Positives = 92/211 (43%), Gaps = 1/211 (0%)
Frame = -2
Query: 740 TIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALT 561
TI++ G++ Q+ YA KA + G T + ++ V+ A++ L S + +
Sbjct: 8 TIYTTTGQIDQLSYAQKAADSGD-TCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIG 66
Query: 560 DRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRP 381
+ IG V TGM +D+ + + + + + ++ + DI +T+ +R
Sbjct: 67 NTIGVVCTGMSSDTFYVGCAIKDYVFHHKENFNEDPTPGMMKVYLNDIFHYFTRGINLRV 126
Query: 380 LGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDD 201
LG + + Y D + ++ TD SG SYKA G T LEK ++ ++
Sbjct: 127 LGANTLTSVYKDGSFSLLH-TDCSGKTLSYKAACIGKGTRRIKTELEK--LDIDTMTIEE 183
Query: 200 AIQLAISCLSQVLSVD-FKSSEIEIGVVSKD 111
+ + + L K +IEIG+ S +
Sbjct: 184 MVDVGVKVLYMAHDPSKDKEFDIEIGIASME 214
>UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome
endopeptidase complex - Candidatus Nitrosopumilus
maritimus SCM1
Length = 210
Score = 52.0 bits (119), Expect = 2e-05
Identities = 48/201 (23%), Positives = 91/201 (45%), Gaps = 2/201 (0%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQ-RKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 498
G T+V ++ D V+ A R + + + + D G + G +AD+++ V
Sbjct: 12 GTTTVGIKAKDGVVLCADMRASAGYFIANNNTMKIQKIDDHAGLTLAGGVADAQNIVDIL 71
Query: 497 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 318
RY + + + I +H L R S ++ QN P +++ YD E GP ++
Sbjct: 72 RYHSNLHRVEKHGPISIHSLARL---CSLIFHQNRGY-PFMADILVGGYDAE-GPALFNI 126
Query: 317 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 138
D G V G+ + LE++ R DL+ ++A ++A+ + + + + +
Sbjct: 127 DMFGSVEKKAYVTTGSGSPVAYGLLEEEY--REDLTVEEAKKIALRAVKAAIVRNIGTGD 184
Query: 137 -IEIGVVSKDNPKFRVLTETE 78
I I ++ KD FR+LTE +
Sbjct: 185 GINIAIMDKDG--FRLLTEEQ 203
>UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 204
Score = 51.6 bits (118), Expect = 2e-05
Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = -2
Query: 668 TSVALRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 492
T+V +R +D V+AA+++V L L S ++ + D++G G++AD ++
Sbjct: 7 TTVGIRVSDGVVLAAEKRVSYGLYLMSKSGKKVYRILDKMGMASAGLMADMQTLA--RIV 64
Query: 491 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 312
EA Y+ S I + +A + + P +++ D+E G +Y DP
Sbjct: 65 EAEMRLYELDSNISPKVWT--VAKLLSYILYERRLFPYYAEIVVGGLDEE-GSHLYSLDP 121
Query: 311 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 135
G VA G+ T + +E KK D+S D+A+ LA+ + + D S + +
Sbjct: 122 IGAIIEDDYVALGSGTQLAISIVESNYKK--DMSLDEALSLALKSVYAAMKRDAASGDGV 179
Query: 134 EIGVVSK 114
++ V+ K
Sbjct: 180 DVLVIGK 186
>UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1628
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/70 (34%), Positives = 41/70 (58%)
Frame = -2
Query: 725 EGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGC 546
+GR++Q+EYA++A+ QG T VAL+ AV+ A ++ P L A + + +G
Sbjct: 704 QGRIHQIEYAMEAVKQGSAT-VALKSKTHAVIVALKRAPSEL--SAHQKKILPIDTHVGV 760
Query: 545 VMTGMIADSR 516
+ G+ AD+R
Sbjct: 761 SIAGLTADAR 770
>UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia
theta|Rep: 26s proteasome SU A6 - Guillardia theta
(Cryptomonas phi)
Length = 235
Score = 46.4 bits (105), Expect = 0.001
Identities = 42/231 (18%), Positives = 102/231 (44%), Gaps = 2/231 (0%)
Frame = -2
Query: 740 TIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALT 561
T+F +G++ Q+E+ALK NQG + + + + + + ++ + ++ + +++
Sbjct: 6 TLFDSDGKILQLEFALKIPNQGKMI-FSFKSINHSYIISE--IHEKKTNNKFFNRFYSID 62
Query: 560 DRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRP 381
+ IG ++G+ D++ + + + V + ++I++ T RP
Sbjct: 63 NNIGLGISGIFFDAKKIFNFCVELNIKIKQAFKNFCSVEYISKKISEAFSNNTLKINQRP 122
Query: 380 LGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDD 201
++ +I + D+ GP +++ G K +G+ L +K + D+
Sbjct: 123 YAINVFIIGFSDK-GPIIFEISTDGLMTYKKTCLSGSSINSYTKELFSIIKNDKKMLNDE 181
Query: 200 AIQLAI-SCLSQVLSVDFKSSEI-EIGVVSKDNPKFRVLTETEIDRHLTAI 54
++ C+ + S S++I + ++ K KF +L + +DR T I
Sbjct: 182 IFMISFYQCIKK--SEKNSSNQIFSLSILGK-KTKFTILNKI-VDRFYTKI 228
>UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome beta subunit -
Pyrobaculum aerophilum
Length = 202
Score = 45.2 bits (102), Expect = 0.002
Identities = 44/196 (22%), Positives = 87/196 (44%), Gaps = 2/196 (1%)
Frame = -2
Query: 668 TSVALRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 492
T+V + D V+A ++V + ++ + D + M+G +AD +S +
Sbjct: 3 TTVGIAVKDGVVLATDKRVTAGYYIAHKRGEKIWKIDDHVAATMSGGVADLQSVLSFLTL 62
Query: 491 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 312
A ++ +Y IP+ L ++ I ++ + + ++ D+E G +Y D
Sbjct: 63 RAHEYKIEYKRPIPISALVNYMSLI--LFYSRPYIYIV--HSIIGGVDEEEGAVLYMVDW 118
Query: 311 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 135
G K +A G+ + LE + R D++ +DA+ LAI + + D S E I
Sbjct: 119 LGTVTKEKYIATGSGSPYAKGALE--VGYREDMTLEDAVDLAIKAVKAAIRNDPGSGEGI 176
Query: 134 EIGVVSKDNPKFRVLT 87
++ V+++ RV T
Sbjct: 177 DVVVITRKEGFKRVFT 192
>UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2;
Oligohymenophorea|Rep: Proteasome subunit beta type -
Tetrahymena thermophila SB210
Length = 227
Score = 44.4 bits (100), Expect = 0.004
Identities = 44/202 (21%), Positives = 80/202 (39%), Gaps = 1/202 (0%)
Frame = -2
Query: 656 LRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANW 477
L G D+ + + DR D H +RI C+ +G AD+++ RY
Sbjct: 38 LVGADSRTTSGSY-IADRAQDKVDYLH-----ERIYCLRSGSAADTQTLCSYVRYYLDVH 91
Query: 476 QYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYC 297
+ V + +++ Y N L ++++ DD GP +Y PSG
Sbjct: 92 SMELQRRPTVKTAAKLFSNLIYQYQDN-----LSAAVIVAGIDDNEGPSIYACQPSGSCI 146
Query: 296 SYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVV 120
+ G+ + +Y++ + DL + A +L + L+ +S D S I + +
Sbjct: 147 KQQVAIGGSGSGFIFSYVDANFRPNMDL--ESAKKLVKTALAHAMSRDGSSGGIIRLVNI 204
Query: 119 SKDNPKFRVLTETEIDRHLTAI 54
+KDN ++ H T I
Sbjct: 205 TKDNVTREFFDHKDLPYHFTNI 226
>UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1;
Spraguea lophii|Rep: 20S proteasome alpha subunit -
Spraguea lophii
Length = 99
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/99 (25%), Positives = 48/99 (48%)
Frame = -2
Query: 680 QGGLTSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 501
Q G T + + D V+ +K + L+ ++D I C + G +D+ +
Sbjct: 5 QNGGTIIGITCNDGVVLFGMKKEKSLI----KYEKLYKISDGIHCCICGNSSDALQMIGY 60
Query: 500 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMR 384
AR +AA ++ ++G IP+ LC+++ I Q +T +R
Sbjct: 61 ARLKAAEFEEEFGIPIPLLTLCKKVGAIKQNFTLGGGLR 99
>UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 195
Score = 44.0 bits (99), Expect = 0.005
Identities = 43/197 (21%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -2
Query: 662 VALRGTDAAVVAAQ-RKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEA 486
+ ++ TD V+ A R + + + + D G + G +AD+++ V RY A
Sbjct: 1 MGIKATDGVVLCADMRASAGYFIANNNTMKIQRIDDHAGLTLAGGVADAQNIVDVLRYHA 60
Query: 485 ANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSG 306
+ + + IP+ L R S ++ QN P +++ + D GP +Y D G
Sbjct: 61 SLHRIRKQGPIPIKSLARL---TSLIFHQNRGY-PFMADILMGGF-DAVGPALYNIDMFG 115
Query: 305 YYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEI 129
V G+ + LE++ R+DL+ D+A +A+ + ++ + + + I +
Sbjct: 116 SVEEKSYVTTGSGSPVAYGTLEEEY--RADLTADEAKGVALRAVKAAITRNIGTGDGINV 173
Query: 128 GVVSKDNPKFRVLTETE 78
V++ + F +LT +
Sbjct: 174 AVINGNG--FELLTREQ 188
>UniRef50_Q9U794 Cluster: Proteasome subunit beta type-1; n=7;
Trypanosomatidae|Rep: Proteasome subunit beta type-1 -
Trypanosoma brucei brucei
Length = 258
Score = 42.3 bits (95), Expect = 0.015
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVP-DRLLDPASVTH-LFALTDRIGCVMTGMIADSRSQV*R 501
G T A+ G++ V+ A ++ D + S T LF LTDRI +GM AD
Sbjct: 52 GGTIAAIAGSNYVVLGADTRLNGDFCIHTRSDTSKLFKLTDRIFLASSGMQADRLQLQQM 111
Query: 500 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 321
+Y +QY G ++P + IA ++ P M++ D++ Y
Sbjct: 112 LKYRIQWYQYNNGGKVP---STKAIAKLTSTMLYQRRFFPYYTFNMIVGIDEKGAGVCYS 168
Query: 320 TDPSG 306
DP G
Sbjct: 169 YDPVG 173
>UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar to
human proteasome (prosome, macropain) subunit, alpha
type, 5(PSMA5),; n=1; Macaca fascicularis|Rep: Testis
cDNA, clone: QtsA-18608, similar to human proteasome
(prosome, macropain) subunit, alpha type, 5(PSMA5), -
Macaca fascicularis (Crab eating macaque) (Cynomolgus
monkey)
Length = 117
Score = 41.1 bits (92), Expect = 0.034
Identities = 24/92 (26%), Positives = 47/92 (51%)
Frame = -2
Query: 347 DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQ 168
DE GP ++ DPSG + A A G+ + + L++ K ++ +AI+ ++ L Q
Sbjct: 23 DEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSSLIILKQ 80
Query: 167 VLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 72
V+ ++ IE+ V + F + T+ E++
Sbjct: 81 VMEEKLNATNIELATV-QPGQNFHMFTKEELE 111
>UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giardia
lamblia ATCC 50803|Rep: Proteasome subunit beta type -
Giardia lamblia ATCC 50803
Length = 254
Score = 38.7 bits (86), Expect = 0.18
Identities = 42/196 (21%), Positives = 86/196 (43%), Gaps = 4/196 (2%)
Frame = -2
Query: 686 INQGGLTSVALRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSRSQ 510
I+ GG T +A+ G D A++A ++ + + +V +F +TD+I +GM AD +
Sbjct: 52 IDNGG-TIIAIAGPDFAMIAGDTRLSEGYNILSRNVRKVFPVTDKIVYAASGMHADVQRL 110
Query: 509 V*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPC 330
+ + E+ + K EI + R ++ + +Y + + P S ++ D E
Sbjct: 111 LKHMKIESTEYYLKTQKEIAIEQFIRLLS--AMMYYRRS--FPWYTSSIVAGIDSEGRGA 166
Query: 329 VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKL--KKRSDLSTDDAIQLAISCLSQVLSV 156
VY D G + +AG L++ + K ++++ + A +L S
Sbjct: 167 VYSYDVIGSTLRTRYGSAGTGNAMICPILDEAILSKNEAEITREFAFELIQSAFRSCAER 226
Query: 155 DFKSSEIEIGV-VSKD 111
D + + + + +S D
Sbjct: 227 DIYTGDSVVAMCISAD 242
>UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum
pernix|Rep: Proteasome beta subunit - Aeropyrum pernix
Length = 203
Score = 38.7 bits (86), Expect = 0.18
Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 1/175 (0%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 498
G T++ +R D V+AA +++ + + +F + DRIG G+ D V
Sbjct: 5 GATALGIRVEDGVVLAADKRMSYGGFILSRNFKKIFVINDRIGIAFAGLYGDMGGLVRIV 64
Query: 497 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 318
+ + G V + + ++ + Y + P ++ D P +Y
Sbjct: 65 EGQMRLASLETGKPATVRNVAKFLSSLLYSY----KFFPFNVEAIVGGIDPGGEPKLYVL 120
Query: 317 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD 153
DP G VAAG LE K+ +S ++A + A+ L ++ D
Sbjct: 121 DPLGSIIEEDYVAAGTGATTAFGLLEHVYKR--GMSLEEAKKAAVEALRASMARD 173
>UniRef50_Q980L4 Cluster: Proteasome subunit; n=4;
Sulfolobaceae|Rep: Proteasome subunit - Sulfolobus
solfataricus
Length = 196
Score = 37.9 bits (84), Expect = 0.32
Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 3/188 (1%)
Frame = -2
Query: 668 TSVALRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 489
T+V L+ D V+A++R++ + ++ G+ D ++ E
Sbjct: 7 TAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVE 66
Query: 488 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 309
++ G I VH + ++ I Y ++ P S +L DE GP +Y DP
Sbjct: 67 IKYYEVSTGKPISVHAAAKLLSVILYQY----KVMPF-ISEILFGGVDEKGPQLYVLDPI 121
Query: 308 GYYC--SYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE- 138
G +Y AV +GA+ G LE + ++S D A QL + + D S +
Sbjct: 122 GSLIEDNYAAVGSGARIAIG--VLESEYD--PNMSLDVATQLITKAIKASIERDITSGDG 177
Query: 137 IEIGVVSK 114
I++ ++ K
Sbjct: 178 IDLAIIDK 185
>UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9;
Magnoliophyta|Rep: Proteasome subunit beta type-2-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 204
Score = 36.3 bits (80), Expect = 0.98
Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Frame = -2
Query: 473 YKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCS 294
YK+ + IP+ ++ T P ++++ YDDE+G +Y D Y +
Sbjct: 67 YKFRNGIPLTTAAAANFTRGELATA-LRKNPYSVNILMAGYDDESGASLYYID---YIAT 122
Query: 293 YKAVAAGAKTVDGNAYLEKKLKK--RSDLSTDDAIQLAISCLSQVLS-VDFKSSEIEIGV 123
V GA G+ + + + RSD+S ++AI+L C+ ++ S + I +
Sbjct: 123 LHKVDKGAFGY-GSYFSLSTMDRHYRSDMSVEEAIELVDKCILEIRSRLVVAPPNFVIKI 181
Query: 122 VSKDNPK 102
V KD +
Sbjct: 182 VDKDGAR 188
>UniRef50_Q8LIW5 Cluster: P0497A05.6 protein; n=6;
Magnoliophyta|Rep: P0497A05.6 protein - Oryza sativa
subsp. japonica (Rice)
Length = 557
Score = 35.9 bits (79), Expect = 1.3
Identities = 21/37 (56%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = -3
Query: 154 TSSPPRLRLVLSAKIILSF--GC*LKLKSTDISRQSL 50
TS P R RLVL+A ++LSF G L LKST+I R L
Sbjct: 46 TSKPGRKRLVLTASVLLSFLIGLPLLLKSTEIHRSPL 82
>UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella
chejuensis KCTC 2396|Rep: Outer membrane protein -
Hahella chejuensis (strain KCTC 2396)
Length = 587
Score = 35.1 bits (77), Expect = 2.3
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = -2
Query: 191 LAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDR 69
LA+S LS + + F S +++ VV +DN + + L E E+DR
Sbjct: 14 LAVSGLSHAIDIPFFSDKLKYEVVVEDNEELKSLVEDELDR 54
>UniRef50_Q0FG88 Cluster: Putative uncharacterized protein; n=1;
alpha proteobacterium HTCC2255|Rep: Putative
uncharacterized protein - alpha proteobacterium HTCC2255
Length = 154
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/71 (28%), Positives = 34/71 (47%)
Frame = -2
Query: 278 AGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKF 99
AG D A E+KL KR+D S +A IS + +L K++E+EI +
Sbjct: 55 AGLLLADRTAASEEKLSKRNDASYSEAPDSEISKHNSILDTKLKAAELEISNLKSQISNQ 114
Query: 98 RVLTETEIDRH 66
+ ++ + D +
Sbjct: 115 HISSDKDTDNN 125
>UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr14 scaffold_54, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 66
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/60 (33%), Positives = 28/60 (46%)
Frame = -2
Query: 275 GAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFR 96
G + +LEK+ D+ DDA+ AI L + S IEIG++ D KFR
Sbjct: 2 GKNVSNAKTFLEKRYT--DDMELDDAVHTAILTLKEGFEGQISSKNIEIGIIGTDR-KFR 58
>UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;
Sulfolobaceae|Rep: Proteasome subunit beta precursor -
Sulfolobus solfataricus
Length = 208
Score = 35.1 bits (77), Expect = 2.3
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 3/166 (1%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSR--SQV* 504
G T+V +R D ++AA R+ + V + +TD+IG G +AD + V
Sbjct: 14 GTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVL 73
Query: 503 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY 324
+ Y N KYG I + + R+A++ + P +++ YDD+ P ++
Sbjct: 74 KNIYH-YNSITKYG-PISIKGIATRLANVLSA----TKYFPYIVQILIGGYDDQ--PRLF 125
Query: 323 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLA 186
D G VA G+ + LE + + ++ D+A LA
Sbjct: 126 NLDYLGDITEENYVATGSGSPVAMGVLEDEYNPK--MTLDEAADLA 169
>UniRef50_UPI0000DB72B7 Cluster: PREDICTED: similar to CG3558-PA,
isoform A; n=2; Apis mellifera|Rep: PREDICTED: similar
to CG3558-PA, isoform A - Apis mellifera
Length = 958
Score = 34.7 bits (76), Expect = 3.0
Identities = 14/48 (29%), Positives = 25/48 (52%)
Frame = -2
Query: 593 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIP 450
PAS+ + L+D + + D+R ++ R +NW Y+Y E+P
Sbjct: 497 PASINYGVRLSDSLYGNYHAYLCDARQKIRACRIACSNWSYQYNGELP 544
>UniRef50_A2WY43 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 507
Score = 34.7 bits (76), Expect = 3.0
Identities = 23/60 (38%), Positives = 33/60 (55%)
Frame = -2
Query: 773 SRSSAGFDRHITIFSPEGRLYQVEYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLD 594
++S G + IT SP+G ++YA+ INQGGL S L + A VPD++LD
Sbjct: 393 TQSMDGVTKFIT--SPKGFAQCLQYAIICINQGGLLS-KLEDPNYMSTAEILNVPDKILD 449
>UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1;
Trichomonas vaginalis G3|Rep: Proteasome subunit beta
type - Trichomonas vaginalis G3
Length = 216
Score = 34.7 bits (76), Expect = 3.0
Identities = 40/195 (20%), Positives = 83/195 (42%), Gaps = 4/195 (2%)
Frame = -2
Query: 674 GLTSVALRGTDAAVVAAQRKVPDRLLDPASVTH-LFALTDRIGCVMTGMIADSR--SQV* 504
G T +A++ TD V+A+ + P T+ + + +I G AD++ ++
Sbjct: 12 GTTLLAIQCTDGVVMASDSRTSSGSFIPNRATNKITEIQPKIFAARCGNAADTQFLARAV 71
Query: 503 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY 324
+ A N + + + + I + Y Q + +++ D AGP VY
Sbjct: 72 KNYLNALNITRENTDDSTILVASNVIRSLIVRYRQYLS------AGVIVGGWDSAGPQVY 125
Query: 323 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKS 144
+ SG K + G+ + AY+++ R D++ ++A + AI+ ++ + D S
Sbjct: 126 SIEVSGMAIKKKIASNGSGSTYIQAYIDQNY--REDMTMEEATKFAIAAVTGAIIRDGSS 183
Query: 143 -SEIEIGVVSKDNPK 102
+ I ++ D K
Sbjct: 184 GGVVNIVQINADGAK 198
>UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Putative
uncharacterized protein - Flavobacteriales bacterium
HTCC2170
Length = 1157
Score = 33.5 bits (73), Expect = 6.9
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = -2
Query: 239 KKLKKRSDLSTDDAIQLAISCLSQ-VLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDR 69
KKL K+ L ++ ++ IS Q L+VDF+ E+G + KDN + + E+++
Sbjct: 662 KKLSKKQSLLSEQKLKEEISAQEQRELNVDFEELANELGELEKDNQDLKKPIDLEVNK 719
>UniRef50_Q6FB05 Cluster: Maf-like protein ACIAD1930; n=2;
Acinetobacter|Rep: Maf-like protein ACIAD1930 -
Acinetobacter sp. (strain ADP1)
Length = 198
Score = 33.5 bits (73), Expect = 6.9
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = -2
Query: 179 CLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLT 60
C S LS+ +S E ++ KFRVLT+ EI+R++T
Sbjct: 107 CFSTGLSIQHLASGFEHTLIEHYQVKFRVLTDAEIERYVT 146
>UniRef50_Q4Q7T3 Cluster: Zn finger protein, putative; n=3;
Leishmania|Rep: Zn finger protein, putative - Leishmania
major
Length = 637
Score = 33.1 bits (72), Expect = 9.1
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Frame = -2
Query: 374 CSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAI 195
C+ L Y+ G + T+ C +A AA A+ D A + L + LST DA+
Sbjct: 43 CNARLALYERVTGAPLEGTETMRDACLAQATAAVAEAADSEAMVPGGLSLSTPLSTHDAL 102
Query: 194 QLAISCLSQ----------VLSVDFKSSEIEIGVVSKDNPK 102
+ + +S+ + SV F S + + V+KD+PK
Sbjct: 103 RPFLPTVSETGTYTCNWCALRSVAFSSRDAFLLHVAKDHPK 143
>UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 485
Score = 33.1 bits (72), Expect = 9.1
Identities = 32/121 (26%), Positives = 54/121 (44%)
Frame = -2
Query: 470 KYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSY 291
KYGS++ + I IS ++ + + L C+ L A +D G + Y+CS
Sbjct: 136 KYGSKLKITTDNYTILSISALFCKIIQTN-LNCA--LSAVND--GIIINAISSIEYFCST 190
Query: 290 KAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 111
+ K V+ N Y+ K L DL + +Q S +S +L + +S E+ + K
Sbjct: 191 GYIGFFCKYVNSNIYILKYLFSYHDLISKAQVQ---SIISTMLKLLITTSSDEVSPIDKR 247
Query: 110 N 108
N
Sbjct: 248 N 248
>UniRef50_A5AB88 Cluster: Contig An08c0230, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An08c0230,
complete genome. precursor - Aspergillus niger
Length = 772
Score = 33.1 bits (72), Expect = 9.1
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
Frame = -2
Query: 749 RHITI--FSPEGRLYQV---EYALKAINQGGLTSVALRGTDAAVVAAQRKVPDRLLDPAS 585
RH+T FSP+ R+ + L+ +N T LRGT A V + PD +
Sbjct: 574 RHLTAVEFSPDSRMVAFGTHDAGLRLLNNATGTFQTLRGTSAEKVNSMTFSPDESILACV 633
Query: 584 VTHLFALTDRIGCVMTGMIADSRSQV 507
V L D C+M ++ R ++
Sbjct: 634 VERDITLWDTTTCMMCSTLSGHRERI 659
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 765,380,927
Number of Sequences: 1657284
Number of extensions: 14522278
Number of successful extensions: 39967
Number of sequences better than 10.0: 143
Number of HSP's better than 10.0 without gapping: 38244
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39816
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 75013275813
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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