Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_F_H18
(772 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 242 6e-63
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 210 4e-53
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 208 1e-52
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 206 5e-52
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 202 1e-50
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 168 1e-40
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 165 8e-40
UniRef50_Q7KT12 Cluster: CG9331-PE, isoform E; n=14; Endopterygo... 164 2e-39
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 161 2e-38
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 157 4e-37
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 155 2e-36
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 153 6e-36
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 150 3e-35
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 147 3e-34
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 144 3e-33
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 135 1e-30
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 130 3e-29
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 130 4e-29
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 130 5e-29
UniRef50_Q0UH86 Cluster: Putative uncharacterized protein; n=1; ... 130 5e-29
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 127 3e-28
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 126 8e-28
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 126 8e-28
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 125 1e-27
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 121 2e-26
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 118 1e-25
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 118 2e-25
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-25
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 115 1e-24
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 114 2e-24
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 113 5e-24
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 113 6e-24
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 112 8e-24
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 112 8e-24
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 111 1e-23
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 111 1e-23
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 110 3e-23
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 107 4e-22
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 4e-22
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 105 9e-22
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 104 2e-21
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 104 3e-21
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 4e-21
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 103 6e-21
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 102 9e-21
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 101 2e-20
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 100 3e-20
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 99 1e-19
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 1e-19
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 98 2e-19
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 98 2e-19
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 97 3e-19
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 4e-19
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 97 4e-19
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 6e-19
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 96 7e-19
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 94 3e-18
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 93 5e-18
UniRef50_Q7PMI6 Cluster: ENSANGP00000021069; n=1; Anopheles gamb... 93 7e-18
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 9e-18
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 93 9e-18
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 92 1e-17
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 92 2e-17
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 4e-17
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 9e-17
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 9e-17
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 89 9e-17
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 89 1e-16
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 88 2e-16
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 2e-16
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 88 2e-16
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 88 3e-16
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 88 3e-16
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 87 3e-16
UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 6e-16
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 87 6e-16
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 86 8e-16
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 8e-16
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 85 1e-15
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 85 2e-15
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 85 2e-15
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 85 2e-15
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 84 3e-15
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 3e-15
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase YN... 84 3e-15
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 4e-15
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 83 1e-14
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 82 1e-14
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 82 1e-14
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 82 1e-14
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 82 1e-14
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 82 2e-14
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 81 3e-14
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 5e-14
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 5e-14
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 80 5e-14
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 80 5e-14
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 80 7e-14
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 80 7e-14
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 9e-14
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 79 9e-14
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 79 9e-14
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 79 1e-13
UniRef50_Q4P4C6 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 79 1e-13
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 79 2e-13
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 79 2e-13
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 79 2e-13
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 78 2e-13
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 78 2e-13
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 78 3e-13
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 4e-13
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 77 4e-13
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 77 5e-13
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 77 6e-13
UniRef50_UPI0000586D88 Cluster: PREDICTED: hypothetical protein,... 76 9e-13
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 76 9e-13
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 9e-13
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 1e-12
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 76 1e-12
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 75 1e-12
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 75 2e-12
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 75 2e-12
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 75 3e-12
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 75 3e-12
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 3e-12
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 75 3e-12
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 75 3e-12
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 75 3e-12
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 75 3e-12
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 74 3e-12
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 74 3e-12
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 74 3e-12
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 5e-12
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 74 5e-12
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 73 6e-12
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 73 6e-12
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 73 8e-12
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 73 8e-12
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 8e-12
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 73 8e-12
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 72 1e-11
UniRef50_Q9A6E7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 2e-11
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 2e-11
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 72 2e-11
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 71 2e-11
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 71 2e-11
UniRef50_Q1E2M0 Cluster: Putative uncharacterized protein; n=3; ... 58 3e-11
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 71 3e-11
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 71 4e-11
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 71 4e-11
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 71 4e-11
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 6e-11
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 70 6e-11
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 6e-11
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 70 7e-11
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 69 1e-10
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 69 1e-10
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 69 1e-10
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 69 1e-10
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 2e-10
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 2e-10
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 69 2e-10
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 2e-10
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 68 2e-10
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q54DP1 Cluster: Gluconate 2-dehydrogenase; n=1; Dictyos... 68 2e-10
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 68 2e-10
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 3e-10
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 67 5e-10
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 67 5e-10
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 67 5e-10
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 67 5e-10
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 67 5e-10
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 67 5e-10
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 67 5e-10
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 67 5e-10
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 5e-10
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 67 5e-10
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 66 7e-10
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 66 7e-10
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 7e-10
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 66 7e-10
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 66 1e-09
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 66 1e-09
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 66 1e-09
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 66 1e-09
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 65 2e-09
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 65 2e-09
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 65 2e-09
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 65 2e-09
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1; Rhi... 64 3e-09
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 64 3e-09
UniRef50_A1W7E2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 64 5e-09
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 64 5e-09
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 64 5e-09
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 5e-09
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 64 5e-09
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 64 5e-09
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 63 6e-09
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 63 8e-09
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 8e-09
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 8e-09
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 62 1e-08
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 62 2e-08
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 62 2e-08
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 61 3e-08
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 61 3e-08
UniRef50_A5V984 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 61 3e-08
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 61 3e-08
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 61 3e-08
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 61 3e-08
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 60 5e-08
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 60 5e-08
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 60 6e-08
UniRef50_Q89Y67 Cluster: Oxidoreductase; n=14; Alphaproteobacter... 60 6e-08
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 60 6e-08
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 60 6e-08
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 6e-08
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 6e-08
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 60 8e-08
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 8e-08
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 8e-08
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 60 8e-08
UniRef50_Q9YCJ2 Cluster: Putative glyoxylate reductase; n=1; Aer... 60 8e-08
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 59 1e-07
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q11BV4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 59 1e-07
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q0V2B9 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 58 2e-07
UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 58 2e-07
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 58 2e-07
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 58 2e-07
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 58 3e-07
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 3e-07
UniRef50_A5AR84 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 57 4e-07
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 6e-07
UniRef50_Q3W8K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 6e-07
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 6e-07
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 57 6e-07
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 7e-07
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 7e-07
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 7e-07
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 7e-07
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 56 7e-07
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 56 1e-06
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 56 1e-06
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 56 1e-06
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 56 1e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 56 1e-06
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 56 1e-06
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 56 1e-06
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 55 2e-06
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 55 2e-06
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 55 2e-06
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 55 2e-06
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 55 2e-06
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 54 3e-06
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 54 3e-06
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 54 3e-06
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 54 4e-06
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 54 4e-06
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 54 5e-06
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 54 5e-06
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 54 5e-06
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 54 5e-06
UniRef50_Q47748 Cluster: D-specific alpha-keto acid dehydrogenas... 54 5e-06
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 54 5e-06
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 53 7e-06
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 53 7e-06
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_A7CWK1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 9e-06
UniRef50_A3S1P6 Cluster: Dehydrogenase; n=1; Prochlorococcus mar... 53 9e-06
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 53 9e-06
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 53 9e-06
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 53 9e-06
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 52 1e-05
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 52 1e-05
UniRef50_Q0HS14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6GPV1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 52 1e-05
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 52 1e-05
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 52 1e-05
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 52 2e-05
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 52 2e-05
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 52 2e-05
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 52 2e-05
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A1RMU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 52 2e-05
UniRef50_Q97IU7 Cluster: Lactate dehydrogenase; n=5; Clostridial... 52 2e-05
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 52 2e-05
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 52 2e-05
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 51 3e-05
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 51 3e-05
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 51 3e-05
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 51 4e-05
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria... 51 4e-05
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 4e-05
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05
UniRef50_A0IKR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 4e-05
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 50 5e-05
UniRef50_Q0S7S0 Cluster: Probable phosphoglycerate dehydrogenase... 50 5e-05
UniRef50_Q03Z77 Cluster: Lactate dehydrogenase related 2-hydroxy... 50 5e-05
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 50 5e-05
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 50 6e-05
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 50 6e-05
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 6e-05
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 50 6e-05
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 50 8e-05
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 8e-05
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 8e-05
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 50 8e-05
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 49 1e-04
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 49 1e-04
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 49 1e-04
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 49 1e-04
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A4AK07 Cluster: Glycerate dehydrogenase; n=1; marine ac... 49 1e-04
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 49 1e-04
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 49 1e-04
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q7Z019 Cluster: Putative D-lactate dehydrogenase; n=1; ... 48 2e-04
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 48 2e-04
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 48 2e-04
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 48 3e-04
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 48 3e-04
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 48 3e-04
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 3e-04
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 48 3e-04
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 48 3e-04
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 48 3e-04
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 48 3e-04
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 48 3e-04
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 48 3e-04
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 48 3e-04
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 47 5e-04
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 5e-04
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 47 5e-04
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 6e-04
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 47 6e-04
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 6e-04
UniRef50_Q0V699 Cluster: Putative uncharacterized protein; n=2; ... 47 6e-04
UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 47 6e-04
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 46 8e-04
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 46 0.001
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q82ZC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 46 0.001
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 46 0.001
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 46 0.001
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 46 0.001
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 46 0.001
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 46 0.001
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 46 0.001
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q1FJY2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A5TSY9 Cluster: Possible dehydrogenase; n=1; Fusobacter... 46 0.001
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 46 0.001
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 45 0.002
UniRef50_Q82ZZ6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 45 0.002
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 45 0.002
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 45 0.002
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q3M599 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q98J55 Cluster: Mlr2095 protein; n=5; Rhizobiales|Rep: ... 44 0.003
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 44 0.004
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 44 0.004
UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3; Mycoplasm... 44 0.004
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 44 0.006
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 44 0.006
UniRef50_Q11GX7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.006
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 44 0.006
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 44 0.006
UniRef50_Q6Z8P7 Cluster: Putative uncharacterized protein P0708B... 44 0.006
UniRef50_A2ZQX8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 43 0.010
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 43 0.010
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 43 0.010
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 43 0.010
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 43 0.010
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.013
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.013
UniRef50_Q1M7M0 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 42 0.017
UniRef50_Q01QI5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.017
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.017
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.017
UniRef50_A4GXJ1 Cluster: D-lactate dehydrogenase; n=4; Lactobaci... 42 0.017
UniRef50_Q1FPN7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.022
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 42 0.022
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 42 0.022
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 42 0.022
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 41 0.030
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 41 0.030
UniRef50_Q2H2H7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.030
UniRef50_Q5V4Z5 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 41 0.030
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 41 0.039
UniRef50_A1WNG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.039
UniRef50_Q89FJ0 Cluster: Bll6710 protein; n=4; Proteobacteria|Re... 40 0.052
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 40 0.052
UniRef50_Q1ISS3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.052
UniRef50_A6VXE9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.052
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.052
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 40 0.068
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 40 0.068
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.068
UniRef50_A6UHC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.068
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.068
UniRef50_Q0TYA3 Cluster: Putative uncharacterized protein; n=2; ... 40 0.068
UniRef50_A1CFW0 Cluster: D-mandelate dehydrogenase, putative; n=... 40 0.068
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 40 0.091
UniRef50_Q2G440 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.091
UniRef50_Q191U4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.091
UniRef50_A1RBK7 Cluster: Putative 2-hydroxyacid-family dehydroge... 40 0.091
UniRef50_A0NJK9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 39 0.12
UniRef50_A5BY55 Cluster: Putative uncharacterized protein; n=2; ... 39 0.12
UniRef50_Q8X0E6 Cluster: Related to D-mandelate dehydrogenase; n... 39 0.12
UniRef50_Q6C5A6 Cluster: Yarrowia lipolytica chromosome E of str... 39 0.12
UniRef50_Q5KLD5 Cluster: Oxidoreductase, putative; n=2; Filobasi... 39 0.12
UniRef50_UPI0000DC2237 Cluster: RIKEN cDNA D030022P06 gene; n=6;... 39 0.16
>UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p -
Drosophila melanogaster (Fruit fly)
Length = 362
Score = 242 bits (593), Expect = 6e-63
Identities = 112/220 (50%), Positives = 152/220 (69%), Gaps = 2/220 (0%)
Frame = +2
Query: 113 IVRNMSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYC 292
I+R MS++ +++YVTR D+ +SG++LL+ C V+ W++ +PVPR+EL++ VAG + +YC
Sbjct: 34 IIRRMSSQ--HKVYVTRPDVDDSGLELLRKSCQVSTWHETNPVPRSELIRVVAGKDALYC 91
Query: 293 SLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXX 472
+LTDK+D E+LDAAGP LK VATISVG+DHIDV EC+KRG+R+G+TPDV
Sbjct: 92 ALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLA 151
Query: 473 XXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
+RR+ EA + GGW SWAP WM G GL G+ VG++GFGRIGQ +A R+ F
Sbjct: 152 LLLATNRRLFEANKQVYNGGWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKP 211
Query: 653 ERIIYFNRSHRPEE-KETGAVKVSFDELLTQSD-FVICCA 766
I Y RS RP+E A V FDE+L +SD V+CCA
Sbjct: 212 TEITYTTRSLRPKEAAAVNARHVDFDEMLRESDLIVVCCA 251
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 210 bits (512), Expect = 4e-53
Identities = 95/211 (45%), Positives = 133/211 (63%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R ++ VTR+ +PE+G+ LLK++CD++ W P+P+ EL+K + + I+C LTDKID E
Sbjct: 377 RPKVLVTRATVPEAGLNLLKNECDLDTWEHTEPIPKPELIKRIKEADAIFCLLTDKIDEE 436
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+L AAG LKV+AT+SVG DH+D+ K R + IGYTP V SRR+
Sbjct: 437 VLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIPIGYTPGVLTDATAELTMALLLATSRRL 496
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
EA G W +W PTWMTGP ++G+ +GIVG GRIG V+ +K+F +I+Y +R+
Sbjct: 497 IEANRAIYRGEWKAWCPTWMTGPKISGSNIGIVGLGRIGLRVSEYLKSFGVAKILYTSRT 556
Query: 680 HRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
+P + GA KV DELL +SDFVI L
Sbjct: 557 EKPAATKLGAQKVDLDELLKESDFVIVTTAL 587
>UniRef50_Q4PP80 Cluster: Putative glyoxylate
reductase/hydroxypyruvate reductase; n=1; Lysiphlebus
testaceipes|Rep: Putative glyoxylate
reductase/hydroxypyruvate reductase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 325
Score = 208 bits (508), Expect = 1e-52
Identities = 95/211 (45%), Positives = 132/211 (62%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R ++ VTR D+PESG+ +LK++ D+ WN+ +P+PR E L V V+GI+C LTDKID E
Sbjct: 3 RQKVLVTRGDIPESGLSILKNKYDLICWNKTTPIPRTEFLSMVKDVDGIFCLLTDKIDEE 62
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+L AG LKVV+T+SVG DH+++ K RG+ +GYTP V SR++
Sbjct: 63 ILSTAGSKLKVVSTMSVGLDHLNLNALKTRGIHVGYTPGVLTDATAELTIGLLLATSRKI 122
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
A H + G W SW+P WM GPGLA +TVGIVG GRIG V +K F +I+Y +R+
Sbjct: 123 IAAEHALRNGEWTSWSPNWMCGPGLANSTVGIVGLGRIGARVGEYLKPFGVNKILYSSRT 182
Query: 680 HRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
+ + K+ VS + LLT+SDF+I L
Sbjct: 183 EKTDAKKFNGQHVSLNTLLTESDFIIVTIAL 213
>UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate
reductase; n=49; Eumetazoa|Rep: Glyoxylate
reductase/hydroxypyruvate reductase - Homo sapiens
(Human)
Length = 328
Score = 206 bits (503), Expect = 5e-52
Identities = 99/211 (46%), Positives = 130/211 (61%), Gaps = 2/211 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKD-QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
+++VTR E V L + C+V W+ P+P EL + VAG +G+ C L+D +D +
Sbjct: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRI 67
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
LDAAG +LKV++T+SVG DH+ + E KKRG+R+GYTPDV RR+P
Sbjct: 68 LDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLP 127
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
EAI E K GGW SW P W+ G GL +TVGI+G GRIGQA+ARR+K F +R +Y R
Sbjct: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP 187
Query: 683 RPEE-KETGAVKVSFDELLTQSDFVICCAXL 772
RPEE E A VS EL QSDF++ L
Sbjct: 188 RPEEAAEFQAEFVSTPELAAQSDFIVVACSL 218
>UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 323
Score = 202 bits (492), Expect = 1e-50
Identities = 98/212 (46%), Positives = 131/212 (61%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKD-QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
+Q+ VTR +P+ +QLLKD C ++ W P+PR ELL V G + I+C LT+KID E
Sbjct: 3 FQVLVTRR-VPDEAIQLLKDANCQLDYWESDEPIPRNELLNRVKGKHAIFCLLTEKIDAE 61
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+LDA GP LKVVAT+SVG+DH++ E +KRG+++G+TP V SRR+
Sbjct: 62 VLDACGPQLKVVATMSVGYDHVNTKEIEKRGLQLGFTPGVLTDATATLNVALLLAVSRRI 121
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
EA EAK GGW +W P WMTG L G+TVG+VGFGRIG AV R+ F + +Y + +
Sbjct: 122 VEAAAEAKNGGWGTWKPMWMTGATLKGSTVGVVGFGRIGIAVCERLAPFGVCKFLYNDIA 181
Query: 680 HRPE-EKETGAVKVSFDELLTQSDFVICCAXL 772
R + K A V D L +SDF+I C L
Sbjct: 182 PREDVSKHLDAKFVDKDTLYAESDFIIACTVL 213
>UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate
reductase/hydroxypyruvate reductase; n=2; Mammalia|Rep:
PREDICTED: glyoxylate reductase/hydroxypyruvate
reductase - Macaca mulatta
Length = 191
Score = 168 bits (409), Expect = 1e-40
Identities = 76/160 (47%), Positives = 102/160 (63%), Gaps = 1/160 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKD-QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
+++VTR PE L + C+V W+ P+P EL + VAG +G+ C L+D++D +
Sbjct: 8 KVFVTRRIPPEGRAALARAADCEVEQWDSDEPIPVKELERGVAGAHGLLCLLSDRVDKRI 67
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
LDAAG +LKV++T+SVG DH+ + E KKRG+R+GYTPDV RR+P
Sbjct: 68 LDAAGANLKVISTLSVGVDHLALDEIKKRGIRVGYTPDVLTDATAELAVSLLLTTCRRLP 127
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQA 622
EAI E K GGW SW P W+ G GL +TVGIVG GRIG+A
Sbjct: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIVGLGRIGEA 167
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 165 bits (402), Expect = 8e-40
Identities = 85/209 (40%), Positives = 125/209 (59%), Gaps = 2/209 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPS-PVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
++ TR+ PE ++ LKD+ D+ +W + + P+PR LKE+ +G++ +LTD+ D E
Sbjct: 2 RLLFTRALDPE-WIEPLKDEHDIRMWTEENIPMPRELFLKELEEADGVFTNLTDRFDVEA 60
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
+ A LKVV+T++VG+D+ID+ E KRGV +G+TP V RR+
Sbjct: 61 FERA-KRLKVVSTMAVGYDNIDIKEATKRGVSVGHTPGVLTEATADLTFALLMATGRRLR 119
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
E+I + W SW P +TG + G T+GI+G GRIGQAVA+R K FN ++Y NRS
Sbjct: 120 ESIDYVRNDQWKSWGPFMLTGQAIYGTTLGIIGMGRIGQAVAKRAKGFNM-TLLYHNRSR 178
Query: 683 RPE-EKETGAVKVSFDELLTQSDFVICCA 766
+ EKE GA S D LL +SD+V+ A
Sbjct: 179 NEQAEKELGATYCSLDHLLARSDYVVLLA 207
>UniRef50_Q7KT12 Cluster: CG9331-PE, isoform E; n=14;
Endopterygota|Rep: CG9331-PE, isoform E - Drosophila
melanogaster (Fruit fly)
Length = 366
Score = 164 bits (399), Expect = 2e-39
Identities = 81/220 (36%), Positives = 128/220 (58%), Gaps = 2/220 (0%)
Frame = +2
Query: 119 RNMSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSL 298
R MSA +++ VT ++P+ G+ LLK+ C++ + Q P+ RAELL+++ GV+G+
Sbjct: 39 RTMSAGKAFKVLVTHPEVPQEGIDLLKENCEI-VQVQSVPINRAELLEKIRGVDGVLWGG 97
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
+ ++ E LDAAGP LK ++T+S G D++DV E K+R + +G+TP V
Sbjct: 98 HEPLNAEALDAAGPQLKSISTMSAGIDYVDVPEVKRRKIPLGHTPTVLNTAVADLAVGLL 157
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
SRR E W ++ W+ G + +TVG GFG IGQA+A+R+ F+ ++
Sbjct: 158 IAASRRFHEGRKTIDNDKWENYHLNWLLGQDIRDSTVGFYGFGGIGQAIAKRLSGFDIDK 217
Query: 659 IIYFNRS--HRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
++Y R H+ E+E A KV FD LL +SDFV+ + L
Sbjct: 218 VLYTTRRRVHKEIEEEFNAKKVDFDTLLAESDFVVIASPL 257
>UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus
vulgaris|Rep: D-lactate dehydrogenase - Octopus vulgaris
(Octopus)
Length = 324
Score = 161 bits (390), Expect = 2e-38
Identities = 79/210 (37%), Positives = 117/210 (55%), Gaps = 4/210 (1%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAGVN--GIYCSLTDKIDT 316
++Y+TR +P G+ L +++ +++ W+ +P EL+K V G G+ C LTD++D
Sbjct: 4 KVYITRR-IPPVGIDLFREKGVEIDFWDSDEAIPHQELVKNVKGKGYAGLLCLLTDQVDA 62
Query: 317 ELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRR 496
E+ +AAGPSLKVV+T+SVG++HID+ CK R + + SRR
Sbjct: 63 EVFEAAGPSLKVVSTLSVGYEHIDLKACKARNIIACNLSKISTDCVSEFAVTLALAVSRR 122
Query: 497 VPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
+ E I + G W W P W+ G A T+G++G GRIG VARR+KAF R+IY +
Sbjct: 123 IEEGIAAVRNGSWGLWKPMWILGSSFANRTIGVLGMGRIGYGVARRMKAFCISRLIYHDI 182
Query: 677 SHRPEEKETGAVKVSFDELLTQSDFV-ICC 763
+E GA V + LL SD + ICC
Sbjct: 183 KESSFAQELGAEFVDLETLLKDSDVICICC 212
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 157 bits (380), Expect = 4e-37
Identities = 78/214 (36%), Positives = 128/214 (59%), Gaps = 5/214 (2%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++++TR ++PE G+++L+D+ +V +W +PR LLK+V V+ + L+++ID E+
Sbjct: 4 KVFITR-EIPEVGIKMLEDEFEVEVWGDEKEIPREILLKKVKEVDALVTMLSERIDKEVF 62
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+ A P L++VA +VG+D+ID+ E KRG+ + TPDV +R V +
Sbjct: 63 ENA-PKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVK 121
Query: 506 AIHEAKTGGW----VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN 673
++G W V+W P W G + G T+GI+G GRIGQA+A+R K FN RI+Y++
Sbjct: 122 GDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNM-RILYYS 180
Query: 674 RSHRPE-EKETGAVKVSFDELLTQSDFVICCAXL 772
R+ + E E+E A ++LL +SDFV+ L
Sbjct: 181 RTRKEEVERELNAEFKPLEDLLRESDFVVLAVPL 214
>UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Rep:
Glyoxylate reductase - Roseiflexus sp. RS-1
Length = 340
Score = 155 bits (375), Expect = 2e-36
Identities = 87/211 (41%), Positives = 122/211 (57%), Gaps = 9/211 (4%)
Frame = +2
Query: 152 YVTRSDMPESGVQLLKDQCDVNLWN-QPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
Y+TR +P++ + ++ C+ LW+ + +PVPR LL+ VA V+GI LTD++DTELL
Sbjct: 6 YITRR-LPQAAIDIVSAACETTLWDDEANPVPRETLLRAVADVDGILTLLTDRVDTELL- 63
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P LKVVA ++VG+D++D+ RGV + TPDV SRRV E
Sbjct: 64 AAAPRLKVVANMAVGYDNVDLPALTARGVLLTNTPDVLTETTADLVWALILAASRRVVEG 123
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
GGW +W+P +M G + GAT+GIVG GRIG AVARR F I+Y NR P
Sbjct: 124 HRLIAAGGWTTWSPMFMVGQDVHGATLGIVGAGRIGSAVARRAVGFGMP-ILYHNRRPSP 182
Query: 689 E-EKETGAV-------KVSFDELLTQSDFVI 757
E + GA+ + D+LL+ +D V+
Sbjct: 183 SLEAQIGAIPGAVIRYAPTLDDLLSTADVVV 213
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 153 bits (370), Expect = 6e-36
Identities = 84/210 (40%), Positives = 123/210 (58%), Gaps = 2/210 (0%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPS-PVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+YVTR +PE + L+++ +V +W+ + VPR LL++ +GI L+D ID EL
Sbjct: 31 VYVTRK-LPEEVLTSLQEKYEVEMWDDENIAVPREILLEKAGEASGILSMLSDPIDRELF 89
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+ + P+LKVVA ++VG D+ID+ ++ V + TPDV +RR+ E
Sbjct: 90 EKS-PNLKVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIE 148
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A + G W SW+P M G + TVGI+G G IG+A ARR K F+ I+Y NRS +
Sbjct: 149 ADKYVREGKWKSWSPLLMAGTDIHHKTVGIIGMGSIGEAFARRAKGFDM-NILYHNRSRK 207
Query: 686 PEEKET-GAVKVSFDELLTQSDFVICCAXL 772
PE +E GA S +ELL+QSD+V+C A L
Sbjct: 208 PEAEEVLGAKYASLEELLSQSDYVVCLAPL 237
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 150 bits (364), Expect = 3e-35
Identities = 79/205 (38%), Positives = 120/205 (58%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+++VT + MP + L + CDV+ W +PR EL+ V GV+GI C LT++ID EL+
Sbjct: 3 KVFVTYN-MPAEQLSRLSEYCDVDAWQGKGSIPRDELMARVEGVDGIICLLTERIDGELI 61
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+++ +LK V+ +SVG DH+DV RG+ +G+TP V +RR+P+
Sbjct: 62 NSS-KNLKAVSCVSVGVDHVDVGTLTARGIPLGHTPGVLVDATADLAFGLLLAAARRIPQ 120
Query: 506 AIHEAKTGGW--VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
+TGGW SW+P G +AG T+GI+G G IGQA+ARR F+ +I ++RS
Sbjct: 121 GDRHVRTGGWQGASWSPKAFLGCSVAGKTLGIIGLGDIGQALARRAAGFDMP-VIAWSRS 179
Query: 680 HRPEEKETGAVKVSFDELLTQSDFV 754
R + G +S +++L QSDFV
Sbjct: 180 GR---EVAGVRTLSLEQVLDQSDFV 201
>UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n=1;
Aedes aegypti|Rep: Glyoxylate/hydroxypyruvate reductase
- Aedes aegypti (Yellowfever mosquito)
Length = 345
Score = 147 bits (356), Expect = 3e-34
Identities = 79/212 (37%), Positives = 119/212 (56%), Gaps = 1/212 (0%)
Frame = +2
Query: 131 AKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKI 310
A R ++ VT SD+P S ++ L+ +CDV + + R E+L+ G GI D++
Sbjct: 27 ANHRPKLLVTCSDVPVSYIETLRRKCDVTVCPGSN---RDEILRATPGAEGILWLTADRL 83
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D +LD AGP LKVV+T++ G D+++ +KR + +G+TP V +
Sbjct: 84 DDAVLDLAGPQLKVVSTLTSGMDYVNAEAFRKRKIALGHTPKVVNNPVADIAVGLMIAAA 143
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYF 670
RR E + W + P WM G + G+TVGIVGFG IGQ +ARR++ F+ R++Y
Sbjct: 144 RRFHEGRMKILNSDWEA-TPQWMLGQDVTGSTVGIVGFGGIGQTIARRLQGFDIGRLLYT 202
Query: 671 NRSHRPEEKETGAVKVSFDELLTQSDFV-ICC 763
R+ +PE + A VSFD LL +SDF+ I C
Sbjct: 203 GRTKKPEAERFAAEYVSFDNLLQESDFIFIVC 234
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 144 bits (348), Expect = 3e-33
Identities = 78/206 (37%), Positives = 116/206 (56%), Gaps = 1/206 (0%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
++ + VTR +P ++ L++ C+V +W + P R EL + V G +G+ L+D+ID E
Sbjct: 87 KHSVLVTRQ-IPGESLKRLREVCEVEVWPEAIPPSREELCRLVKGRHGLLTMLSDRIDGE 145
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
L+D AG L VV+ +VG ++IDV K RGV +G TPDV SR V
Sbjct: 146 LMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHV 205
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
A ++ + G W +W PT G + T+GIVG GRIG+A A+R+ ++Y +RS
Sbjct: 206 LPAGNQVREGEWKTWEPTGWLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLLYTSRS 265
Query: 680 HRPE-EKETGAVKVSFDELLTQSDFV 754
+ + EKE G +V D LL +SDFV
Sbjct: 266 DQGDVEKELGGRRVELDTLLAESDFV 291
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 135 bits (327), Expect = 1e-30
Identities = 74/206 (35%), Positives = 114/206 (55%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
+YQ+ V P + + +C V W++ P+PR L + +A G+ + ++D E
Sbjct: 3 KYQVVVAGKMRP-CALAKISSECHVRQWDKIEPIPRNLLYEWLADAEGLVSTGDVRVDDE 61
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
LL A P L+V+A SVG+D++D+A C +RG+ G TP V +RR+
Sbjct: 62 LL-AHAPRLRVIAQASVGYDNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRI 120
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
E ++ +G W++ G L G T+GIVG GRIG AVARR KA ++IY NRS
Sbjct: 121 HEGWNQVASGRWLNNHDV-PFGIDLYGKTLGIVGMGRIGAAVARRAKACGM-KVIYHNRS 178
Query: 680 HRPEEKETGAVKVSFDELLTQSDFVI 757
R +++ GA V+FD+LL Q+D ++
Sbjct: 179 RRTDDEHLGATYVAFDDLLAQADCIV 204
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 130 bits (315), Expect = 3e-29
Identities = 70/203 (34%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
+Y+TRS +PE + L+ CDV + + R EL+ V G + + LTD +D E+LD
Sbjct: 6 VYITRS-IPEQTIAELRKTCDVEVNPHDRALTREELMNAVKGRDAVITLLTDNVDAEILD 64
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AAGP K++A +VG ++ ++ KRGV + TP V ++R+ E+
Sbjct: 65 AAGPQCKIIANYAVGFNNFNLDAATKRGVIMTNTPGVLDKATATHAWALLLATAKRISES 124
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
+ G W W+P G + G T+GI G GRIG AR+ AF+ ++IY N
Sbjct: 125 ERYVREGKWKGWSPMTFIGQDVDGKTLGIAGLGRIGTMFARKAAAFDM-KVIYTNEQRNF 183
Query: 689 E-EKETGAVKVSFDELLTQSDFV 754
+ EK+ GA V + LL +SDF+
Sbjct: 184 DFEKDHGATFVDKETLLKESDFL 206
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 130 bits (314), Expect = 4e-29
Identities = 73/201 (36%), Positives = 112/201 (55%), Gaps = 2/201 (0%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+PE G++LLKD DV ++++ + EL + V + + L+ K+ E++DAA PSLK
Sbjct: 10 IPEIGLELLKDH-DVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDAA-PSLK 67
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTG 529
+VA G+D+ID ++G+ + TP V +RR+PE +T
Sbjct: 68 IVANYGAGYDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTT 127
Query: 530 GWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE-EKETG 706
G+ WAP + G + G T+GI+G G IG+AVA+R KAF I+Y + +PE E E
Sbjct: 128 GFNGWAPLFFLGREVHGKTIGIIGLGEIGKAVAKRAKAFGM-NILYTGPNRKPEAESELE 186
Query: 707 AVKVSFDELLTQSDFV-ICCA 766
A V+ +ELL +DF+ I CA
Sbjct: 187 ATYVTLEELLQTADFITINCA 207
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 130 bits (313), Expect = 5e-29
Identities = 80/211 (37%), Positives = 112/211 (53%), Gaps = 2/211 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQP-SPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
+I VTR +P+ V+ LK V +W +P+ R L V +L++ ID E+
Sbjct: 3 KILVTRQ-IPQHYVEQLKKIGQVVMWEHDLTPMSRESFLANVEDATACVITLSEHIDEEV 61
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
A LKV+A ++VG D+ID++ KK GV + TP V +RR+
Sbjct: 62 FLRA-QQLKVIANMAVGFDNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRII 120
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
EA + G W SW P ++G + GATVGI G G IG+A ARR++ F+ RIIY NR
Sbjct: 121 EATSYIQEGKWKSWGPYLLSGKDVYGATVGIFGMGDIGKAFARRLQGFDA-RIIYHNRKR 179
Query: 683 RPE-EKETGAVKVSFDELLTQSDFVICCAXL 772
E++ A V+F LL QSDF+IC A L
Sbjct: 180 DLNAERDLNATYVTFKSLLEQSDFIICTAPL 210
>UniRef50_Q0UH86 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 339
Score = 130 bits (313), Expect = 5e-29
Identities = 79/223 (35%), Positives = 112/223 (50%), Gaps = 16/223 (7%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQL--LKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
++ VTR + E+ L K+ ++ W+ P PR+ LL+ G GI L+D+++ E
Sbjct: 5 KVVVTRQLIDEAQTILDGKKEDLEIVQWSSEKPCPRSWLLENAQGATGILVMLSDQVNEE 64
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
L+ AAG LK +A+ SVG DH+D KKR +R+GYTP RR
Sbjct: 65 LVQAAGHQLKAIASFSVGTDHVDREALKKRNIRLGYTPTCLTDAVADLTVMLILMAQRRG 124
Query: 500 PEAIHEAKTGGW--VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN 673
EAI + G W + W P MTGP + GATVG +GFGRI QA R+ F ++ IY
Sbjct: 125 GEAISKVTKGEWPQMPWHPLLMTGPQIRGATVGFLGFGRIAQASLVRLMGFGIKKAIYLT 184
Query: 674 RSHRPEEKE-------TGAVKV----SFDELLTQSDFVIC-CA 766
KE G + + S D+L ++SD V+ CA
Sbjct: 185 SKPGKSVKEDHFGLLKEGKIPIEPAQSADQLASESDVVVVGCA 227
>UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 357
Score = 127 bits (306), Expect = 3e-28
Identities = 62/140 (44%), Positives = 83/140 (59%), Gaps = 2/140 (1%)
Frame = +2
Query: 275 VNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXX 454
V G L++K+D E LDAAG SLKV++T+SVG+DHID+A CK+RGVR+G TP V
Sbjct: 54 VCGAVICLSEKVDAEFLDAAGASLKVISTMSVGYDHIDLALCKERGVRVGNTPRVLDDAV 113
Query: 455 XXXXXXXXXXXSRRVPEAIHEAKTGGWVS--WAPTWMTGPGLAGATVGIVGFGRIGQAVA 628
+R+VP AI + G W W PT TGP + G T+G +GFG I Q++
Sbjct: 114 AEVCLLLALMVTRQVPLAIRTVRQGEWPQNPWTPTCFTGPQIRGKTIGFLGFGNISQSLC 173
Query: 629 RRVKAFNTERIIYFNRSHRP 688
+ + AF RI+Y RP
Sbjct: 174 KLLVAFKPARIVYTTSKPRP 193
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 126 bits (303), Expect = 8e-28
Identities = 74/204 (36%), Positives = 118/204 (57%), Gaps = 1/204 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
+++VTR+ +P + L+++ +V + ++ +P+AELLK V G G+ ++ D+ID E+
Sbjct: 29 KVFVTRT-LPGKALDRLRERGLEVEV-HRGLFLPKAELLKRVEGAVGLIPTVEDRIDAEV 86
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
+D A LKV+A SVG DH+D+ ++RG+R+ +TP V +RRV
Sbjct: 87 MDRA-KGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVV 145
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
E A+ G W +W P + G L G T+G+VG GRIGQAVA+R AF R++Y R+
Sbjct: 146 EGAAYARDGLWRAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGM-RVVYHARTP 204
Query: 683 RPEEKETGAVKVSFDELLTQSDFV 754
+P +S +ELL ++D V
Sbjct: 205 KPLPYPF----LSLEELLKEADVV 224
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 126 bits (303), Expect = 8e-28
Identities = 65/160 (40%), Positives = 91/160 (56%)
Frame = +2
Query: 275 VNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXX 454
V G+ LT +D LLDA P L+VV+ ++VG D++DV C R +R+G TP V
Sbjct: 52 VVGLLTLLTRPVDAALLDAF-PELRVVSNMAVGFDNVDVPACTARSIRVGNTPGVLTDAT 110
Query: 455 XXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARR 634
+R +P A +A+ G W +W+PT G L GAT+G+VG G+IG AVA+R
Sbjct: 111 ADLAMALLLSAARNLPAASLDAREGRWQTWSPTGWLGLELRGATLGVVGLGKIGLAVAQR 170
Query: 635 VKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
+AF + I+Y RS P E GA +V D LL ++D V
Sbjct: 171 ARAFGMD-ILYTRRSDAPAPPELGATRVELDALLARADVV 209
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 125 bits (302), Expect = 1e-27
Identities = 67/205 (32%), Positives = 114/205 (55%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+++VT + +PE G+ +LK++ +V+++ + + E++K + I L D ID E +
Sbjct: 2 RVFVTYA-IPEKGINMLKERFEVDVYTGEEFLSKEEMIKRAEYADAIVTQLRDPIDKEFI 60
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+ + K++A +VG+++ID+ K+RG+ + TP V +RR+ E
Sbjct: 61 YSLKKA-KIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVE 119
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
+ + G +V W P G L G T+G++G GRIGQAVARR F I+Y+NR+
Sbjct: 120 SDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARRALGFGM-NIVYYNRNRL 178
Query: 686 PE--EKETGAVKVSFDELLTQSDFV 754
PE EK+ A V+ DEL+ SD++
Sbjct: 179 PEEIEKQYNAKYVNIDELVEISDYI 203
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 121 bits (292), Expect = 2e-26
Identities = 71/202 (35%), Positives = 108/202 (53%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
+Y+ R+ +P + L++ +V P P PR L++E + + D++D L+D
Sbjct: 5 LYLVRA-LPGGELAPLRELFEVR-GGAPRPPPRERLVEEAREAAVLVPTYIDRVDAALVD 62
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
A P+L+ VA+ VG +H+D+ C++RGV + TP V +RRV E
Sbjct: 63 AL-PALRHVASYGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEG 121
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
+ GGW P WM G + G TVG+VGFGRIGQA ARR + F+T R++Y S R
Sbjct: 122 DRVVRAGGWTEVDPAWMLGTEVTGKTVGVVGFGRIGQAFARRARGFDT-RVLY--TSPR- 177
Query: 689 EEKETGAVKVSFDELLTQSDFV 754
+ A +V + LL ++DFV
Sbjct: 178 DAGVAWAERVGLERLLAEADFV 199
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 118 bits (285), Expect = 1e-25
Identities = 66/205 (32%), Positives = 110/205 (53%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++++ ++ LL+ Q ++ + + + AEL++ VA + + L+ ++D ++L
Sbjct: 3 KVFIAGQLPAQANTLLLQSQLVIDTYTGDNLISHAELIRRVADADFLIIPLSTQVDQDVL 62
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
D A P LK++A G ++ID+A KR + + TP+V + R+ E
Sbjct: 63 DHA-PHLKLIANFGAGTNNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVE 121
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
H +T G+ WAP + G L G T+GI+G G+IGQAVA+R+ AF+ I+Y
Sbjct: 122 GDHLMRTSGFNGWAPLFFLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMP-ILYSQHHRL 180
Query: 686 PEEKET--GAVKVSFDELLTQSDFV 754
P +ET GA VS DELL ++D V
Sbjct: 181 PISRETQLGATFVSQDELLQRADIV 205
>UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3;
Archaea|Rep: Gluconate 2-dehydrogenase - Picrophilus
torridus
Length = 310
Score = 118 bits (284), Expect = 2e-25
Identities = 63/169 (37%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 254 LLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTP 433
L++ + +GI +L+D+ID+E++DAA LKV++T SVG+DHIDV R ++IGYTP
Sbjct: 34 LMESINDADGILITLSDRIDSEIIDAA-KKLKVISTYSVGYDHIDVKYALSRNIKIGYTP 92
Query: 434 DVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW-VSWAPTWMTGPGLAGATVGIVGFGR 610
DV +RR+ + W W P +M G + G T+GI+G GR
Sbjct: 93 DVLTESTADFIFGLIICIARRICSGYETIISNKWEYRWKPDFMLGHDVYGKTLGILGLGR 152
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFVI 757
IG AV RR F+ +IY+NR+ R G +EL ++SDF++
Sbjct: 153 IGHAVMRRASGFDM-NVIYYNRTERDVNGHVG-----LNELFSRSDFIV 195
>UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 333
Score = 116 bits (280), Expect = 5e-25
Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 1/196 (0%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+P + ++ LK Q ++ +W++ P+P A++ + + I CSL I +L+ + P L
Sbjct: 23 LPTTVLEALKQQFELQVWDE-GPMPTAQIAQWAKTTDAILCSLGTPISADLI-RSNPQLS 80
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTG 529
+++ISVG DHID+A + +G+TPDV +RRV EA + G
Sbjct: 81 TISSISVGVDHIDMAAATAASLPVGHTPDVLVDSTADLALALMLAATRRVVEADRFVRGG 140
Query: 530 GW-VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETG 706
W WA + G L+ ATVGIVG G G AV +RV+AF + +I +NR+ E + G
Sbjct: 141 HWSADWATDFFLGTDLSRATVGIVGLGPTGLAVVKRVRAFGAD-VIGWNRT---EREVLG 196
Query: 707 AVKVSFDELLTQSDFV 754
V+ D+L ++D V
Sbjct: 197 VRNVALDDLFAEADIV 212
>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=16; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Silicibacter pomeroyi
Length = 330
Score = 115 bits (277), Expect = 1e-24
Identities = 70/213 (32%), Positives = 105/213 (49%), Gaps = 3/213 (1%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTD 304
M++K R + VTR P + L ++ D +P+ AE +A + I ++TD
Sbjct: 7 MNSKPR--VLVTRR-WPAAVEAQLAERFDTQFNRTDTPLTSAEFRSALARFDAILPTVTD 63
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
K+ E LD P +++A VG+ HID + G+ + TPDV
Sbjct: 64 KLGAEALDVTAPQTRLLANYGVGYSHIDSDAVRAHGITVSNTPDVLSECTADIAMTLMLM 123
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+RR E E + G W W PT + G ++G +GIVGFGRIGQA+A+R +I+
Sbjct: 124 VARRAGEGERELRAGQWTGWRPTHLVGSKVSGKVLGIVGFGRIGQAMAQRAHHGFGMKIL 183
Query: 665 YFNRSHRPEE--KETGAVKV-SFDELLTQSDFV 754
NRS P++ GA +V + D +L Q DFV
Sbjct: 184 VQNRSAVPQDVLDRYGATQVETLDAMLPQCDFV 216
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 114 bits (275), Expect = 2e-24
Identities = 72/206 (34%), Positives = 110/206 (53%), Gaps = 3/206 (1%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R +I +TR + + L + D+ +++ P+PR L++ ++G + + C D ID
Sbjct: 36 RKRILLTRR-LQDFAQARLGRRYDLEVYSGRVPMPRRALIRAISGAHALVCFPYDVIDAG 94
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
++DAA P L+ +AT SVG+DHIDVA + RG+ +GYTPDV RRV
Sbjct: 95 VMDAA-PDLETIATYSVGYDHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRV 153
Query: 500 PEAIHEAKTGGW--VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN 673
E + G W + A ++ G + G T+GI+G GRIG VA+R AF ++IY +
Sbjct: 154 TEGDRIIRAGRWRQIYGADDYL-GTDVGGKTLGILGMGRIGSRVAKRAAAFGM-KVIYHS 211
Query: 674 RSHRPEEKETG-AVKVSFDELLTQSD 748
RS TG +V+ LL +SD
Sbjct: 212 RS------STGPGTRVTLGRLLERSD 231
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 113 bits (272), Expect = 5e-24
Identities = 62/205 (30%), Positives = 108/205 (52%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
++Y+ +PE G+ LLKDQ +V+++ + + L + V + + L+ +D E+
Sbjct: 3 KVYIA-GPIPEVGLNLLKDQGFEVDMYEGTGIIDKETLKQGVKDADALISLLSTSVDKEV 61
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
+DAA +LK++ G +++D+ +++ + + TP +RR+P
Sbjct: 62 IDAAN-NLKIITNYGAGFNNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIP 120
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
E +T G+ WAP + G ++G T+GI+G G IG AVARR KAF+ I+Y
Sbjct: 121 EGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRAKAFDM-NILYTGPHQ 179
Query: 683 R-PEEKETGAVKVSFDELLTQSDFV 754
+ +E+E GA V + LL +DFV
Sbjct: 180 KVDKEREIGAKYVDLETLLKNADFV 204
>UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus
Pelagibacter ubique|Rep: Probable dehydrogenase -
Pelagibacter ubique
Length = 317
Score = 113 bits (271), Expect = 6e-24
Identities = 71/208 (34%), Positives = 104/208 (50%), Gaps = 2/208 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I +TR + ES + K D L +++L++ G + I SLTDK+D E +
Sbjct: 3 KIIITRRLLKESEEKASKT-FDAKLNGNDELYSQSKLIELSEGHDAILTSLTDKMDEETI 61
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
S+KV++ +VG +ID+ KKRG+ + TP+V RRVPE
Sbjct: 62 SKLPDSIKVISNFAVGFGNIDLEAAKKRGIAVTNTPEVLSDATAEIGILLILGACRRVPE 121
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
+ AK W W+ ++ G L G +GI+G GRIGQ +A+ K+ I Y NRS
Sbjct: 122 GVQAAKESSW-KWSADYLIGKQLTGTRLGILGMGRIGQKIAKIAKSLGM-IIHYHNRSKL 179
Query: 686 PEEKETGAV-KVSFDELLTQSDFV-ICC 763
+EKE GA+ S L SD + ICC
Sbjct: 180 SDEKEQGAIYHDSIKSLFGVSDVLSICC 207
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 112 bits (270), Expect = 8e-24
Identities = 69/215 (32%), Positives = 108/215 (50%), Gaps = 5/215 (2%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTD 304
MS K + + +TR +P+ +++ D L + + E++ + + + +TD
Sbjct: 27 MSNKKKPMVVLTRK-LPDPVETRMRELFDARLNIDDHRMSQPEIIAALKEADVLVPCITD 85
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
ID +++ AGP+LK++A G D+IDVA +RG+ + TP+V
Sbjct: 86 VIDAAVIEQAGPNLKLIANFGNGVDNIDVAAAARRGITVTNTPNVLTEDTADMTLALLLS 145
Query: 485 XSRRVPEAIH--EAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
RR+ E + + G W W+PTWM G + G +GIVG GRIG AVARR KAF
Sbjct: 146 VPRRLVEGANVINERHGQWPGWSPTWMLGRRIWGKRLGIVGMGRIGTAVARRAKAFGLS- 204
Query: 659 IIYFNR---SHRPEEKETGAVKVSFDELLTQSDFV 754
I Y NR S + EE+ S D++L + D +
Sbjct: 205 IHYHNRKRVSPQVEEELEATYWDSLDQMLARMDII 239
>UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 323
Score = 112 bits (270), Expect = 8e-24
Identities = 61/192 (31%), Positives = 96/192 (50%), Gaps = 1/192 (0%)
Frame = +2
Query: 194 LKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVG 373
L+ + D+ + + + + + + G ++ + T+ I E++ P LK +AT+SVG
Sbjct: 23 LRQRFDLEVNLEDTVLTPSGIASRAHGAEVLFVTATEAITAEVIRKLQPGLKTIATLSVG 82
Query: 374 HDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPT 553
+DHID+A + G+++ +TPDV RR EA ++G W W PT
Sbjct: 83 YDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVLNACRRGYEADRMVRSGSWPGWGPT 142
Query: 554 WMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAV-KVSFDE 730
+ G GL G +GI G GRIG+A+A R + F I Y NR+ E GA+ + D
Sbjct: 143 QLLGMGLTGRRLGIFGMGRIGRAIATRARGFGL-AIHYHNRTRLSHALEEGAIYHDTLDS 201
Query: 731 LLTQSDFVICCA 766
LL SD + A
Sbjct: 202 LLGASDIFLIAA 213
>UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillus
clausii KSM-K16|Rep: 2-ketogluconate reductase -
Bacillus clausii (strain KSM-K16)
Length = 321
Score = 111 bits (268), Expect = 1e-23
Identities = 67/205 (32%), Positives = 105/205 (51%), Gaps = 2/205 (0%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
+++ RS +P++ + + C + +W++ P+ R L E+A V+G + DTEL+
Sbjct: 6 VFLARS-LPDAALNHISQFCHLRIWDESKPLTREALAHELADVDGAMLTGIGA-DTELVK 63
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
A LKV++T +VG+D DVA ++ + + TP V +RR+
Sbjct: 64 HAS-KLKVISTATVGYDGFDVAGLAEQNIYVTNTPYVLDETVADLLFGLILSGARRIAPL 122
Query: 509 IHEAKTGGWVSWAPTW-MTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
+ K G W + G + T+GIVG GRIG+ + R K +I+Y NRS R
Sbjct: 123 HEQVKAGNWTKQTTAQSLYGQDVYNQTLGIVGMGRIGEKIVHRAKEGFGMKILYHNRSSR 182
Query: 686 PE-EKETGAVKVSFDELLTQSDFVI 757
PE EK+ GA KV ELL Q+D V+
Sbjct: 183 PEVEKKYGAKKVELHELLEQADVVV 207
>UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5;
Burkholderiales|Rep: 2-hydroxyacid dehydrogenase -
Ralstonia solanacearum UW551
Length = 331
Score = 111 bits (268), Expect = 1e-23
Identities = 72/209 (34%), Positives = 109/209 (52%), Gaps = 3/209 (1%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R + VTR+ P+ +L ++ DV + + +EL++ + G G+ + +++ID
Sbjct: 2 RPSVLVTRATFPDIANRL-REHFDVTDNPSDTILSPSELIERLQGKQGVMSTGSERIDAA 60
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
LLDA P LK V + VG++++DVA C RGV + TPDV +RR+
Sbjct: 61 LLDAC-PGLKAVCNVGVGYNNVDVAACTARGVVVTNTPDVLTQTTADFGFALMLATARRI 119
Query: 500 PEAIHEAKTGGW-VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
E+ + G W + M G + GAT+GI+G GRIGQA+ARR ++IY NR
Sbjct: 120 TESERFVRRGEWQKTGIYNQMLGSDIYGATLGILGMGRIGQAIARRAALGFEMQVIYHNR 179
Query: 677 SH-RPE-EKETGAVKVSFDELLTQSDFVI 757
S PE E A V D LL ++D +I
Sbjct: 180 SPLTPETEARAHARYVDKDTLLREADHLI 208
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 110 bits (265), Expect = 3e-23
Identities = 70/205 (34%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLW--NQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
+I+VTR +P +++L+ + L ++ R EL+ +G L+DKID E
Sbjct: 1 RIFVTRR-LPREAMEILERDPHIELRVNSEDRGCTRDELVSGFQWADGALTMLSDKIDRE 59
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
LL+ A P L+VVA +VG+++ID+ +R V + TP +RR+
Sbjct: 60 LLEVA-PRLRVVANYAVGYNNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRL 118
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
E + G + WAP ++ G L G T+GI+G G IG VARR +AF RI+Y R
Sbjct: 119 VEGDGLVRAGLFKGWAPEFLLGMDLHGKTLGIIGLGEIGTCVARRARAFGM-RIVYCARH 177
Query: 680 HRPEEKETGAVKVSFDELLTQSDFV 754
P E A +V ELL +SD V
Sbjct: 178 EAPTASELQAERVELPELLRRSDVV 202
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 107 bits (256), Expect = 4e-22
Identities = 60/174 (34%), Positives = 88/174 (50%), Gaps = 2/174 (1%)
Frame = +2
Query: 239 VPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVR 418
+PR E+L +V V+ I C DK D EL+ A G LKV++ G+D +DV +R +
Sbjct: 11 MPREEVLHKVTDVDAIICHGKDKADAELV-AKGSKLKVISNFGAGYDTVDVKAATERNIW 69
Query: 419 IGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMT--GPGLAGATVG 592
+ TP RR EA + G W + G G T+G
Sbjct: 70 VCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGKTLG 129
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
I+G G IG+A+A+R A + R+IY+ R+ P+E+E GA S D+LL +SDF+
Sbjct: 130 IIGMGNIGKALAKRAAALDM-RVIYYKRTPLPKEEENGATYKSMDDLLAESDFI 182
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 107 bits (256), Expect = 4e-22
Identities = 71/219 (32%), Positives = 112/219 (51%), Gaps = 11/219 (5%)
Frame = +2
Query: 149 IYVTRSDMPE--------SGVQL-LKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLT 301
+Y+TRS P+ +G L + D +W++ + PR L + + + ++
Sbjct: 1 MYLTRSTFPKLLYDTLRNAGFDLEVWDNKGHGMWDRAAAPPRDVLRDAASRCDALVVTIG 60
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
D++D +L A +KV+AT SVG+DHID+ +RG+ +GYTP+V
Sbjct: 61 DRVDDYVLSNA--KVKVIATYSVGYDHIDLDAATRRGIPVGYTPEVLVEAVADLAIGLII 118
Query: 482 XXSRRVPEAIHEAKTG-GWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
+RRV E ++G + W G + G T+GI+G G IG AVARR KAFN
Sbjct: 119 TLARRVIEGDRLVRSGEAYKVWGE--FLGTEVWGKTLGILGLGNIGAAVARRAKAFNM-N 175
Query: 659 IIYFNRSHRP-EEKETGAVKVSFDELLTQSDFVICCAXL 772
+IY++R+ +P E G V +EL QSD+++ L
Sbjct: 176 VIYWSRTRKPWIEVALGLRYVDLNELFRQSDYLVLTVAL 214
>UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2;
Hyphomicrobium methylovorum|Rep: Glycerate dehydrogenase
- Hyphomicrobium methylovorum
Length = 322
Score = 105 bits (253), Expect = 9e-22
Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 4/198 (2%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+PE+ + ++ DV + E+++ V+ + +L +K E++D ++K
Sbjct: 12 LPEAAMARARESYDVIAHGDDPKITIDEMIETAKSVDALLITLNEKCRKEVIDRIPENIK 71
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTG 529
++T S+G DHID+ CK RG+++G P +RR E +T
Sbjct: 72 CISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTR 131
Query: 530 GWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGA 709
W W P + G L T+GI GFG IGQA+A+R + F+ + I YF+ +HR + +
Sbjct: 132 SWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMD-IDYFD-THRASSSDEAS 189
Query: 710 VKVSF----DELLTQSDF 751
+ +F D LL+ S F
Sbjct: 190 YQATFHDSLDSLLSVSQF 207
>UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=15; Firmicutes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Bacillus anthracis
Length = 330
Score = 105 bits (252), Expect = 1e-21
Identities = 68/205 (33%), Positives = 101/205 (49%), Gaps = 1/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++Y+ +P L + CD W Q VPR LL+++ +G+ + I+ ELL
Sbjct: 14 KVYIAEP-VPTFVENYLSEHCDYEKWEQNEKVPRDVLLEKIQDKDGLL-NFGSAINEELL 71
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+AA P+LKVV+ ISVG+D+ D+ K V TP V RRV E
Sbjct: 72 EAA-PNLKVVSNISVGYDNFDLQAMAKHNVIGTNTPYVLDDTVADLVFALMLSAGRRVCE 130
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
K G W + G + +T+GI+G GRIG+AVA+R K ++Y+NR +
Sbjct: 131 LDSYVKNGEWNAEIGKEHFGLDVHHSTIGIIGMGRIGEAVAKRAKFGFDMDVLYYNRRRK 190
Query: 686 PE-EKETGAVKVSFDELLTQSDFVI 757
E E++ A LL QSDF++
Sbjct: 191 EEAEQKFDATYCDLQTLLKQSDFIV 215
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 105 bits (252), Expect = 1e-21
Identities = 65/177 (36%), Positives = 92/177 (51%), Gaps = 2/177 (1%)
Frame = +2
Query: 236 PVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGV 415
P R EL G +LT+++D E+LDAAG L+VVA ++VG+D+IDVA GV
Sbjct: 36 PPTRDELAAGFTGACAAVVTLTERVDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGV 95
Query: 416 RIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKT-GGWVSWAPTWMTGPGL-AGATV 589
+ TP V +RRV + ++ W+ W P +TG + AGAT+
Sbjct: 96 TVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWI-WGPRMLTGLDVSAGATL 154
Query: 590 GIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFVIC 760
GI+G+GRIG+AVARR +AF + + R + V D LL SD V+C
Sbjct: 155 GILGYGRIGRAVARRARAF--DMTVLATSRRRTSGADDDVWFVDTDTLLADSD-VVC 208
>UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to
ENSANGP00000021023; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021023 - Nasonia
vitripennis
Length = 519
Score = 104 bits (250), Expect = 2e-21
Identities = 55/158 (34%), Positives = 82/158 (51%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
TD +D ++ AG LK+++T S G+DH+++ E KKRG+++G+ P V
Sbjct: 257 TDHVDKNII--AGSKLKIISTPSAGYDHMNIQEIKKRGIKVGHAPKVLSGAVAETAVFLL 314
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
+RR E + G V W+ G L TVGIVG G IG+ + +R+K F ++
Sbjct: 315 LGAARRAHEGRLLLEQGK-VENGFQWLLGHDLRNKTVGIVGLGNIGEEIVKRLKPFEIKK 373
Query: 659 IIYFNRSHRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
Y S + + GA V+ D LL +SDFVI C L
Sbjct: 374 FFYTGHSRKKAGDDLGAEFVNLDTLLKESDFVISCVPL 411
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 104 bits (249), Expect = 3e-21
Identities = 73/216 (33%), Positives = 108/216 (50%), Gaps = 8/216 (3%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQP-SP-----VPRAELLKEVAGVNGIYCSLTDKI 310
I+V+R PES + L++ V ++ SP VP+ L+ + + D I
Sbjct: 4 IFVSREGFPESMYKKLEEVGRVEVYRHGGSPWSTRGVPKEVLIDAARRCEALVIFIGDVI 63
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D E+LDA G LK+V+T SVG DHIDV K++GV + +TP V +
Sbjct: 64 DKEVLDA-GEKLKIVSTASVGVDHIDVEYAKRKGVVVAHTPYVLVDAVADLAVGLLIAVT 122
Query: 491 RRVPEAIHEAKTGGWVS-WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
R++ ++G + W + G L G GIVG G IG A+ARR+KAF+ E + Y
Sbjct: 123 RKIALGDRLIRSGAADAVWGS--LMGVNLRGKRAGIVGLGNIGVAIARRLKAFDIE-VAY 179
Query: 668 FNRSHRPE-EKETGAVKVSFDELLTQSDFVICCAXL 772
++R +PE E G + D LL+ SDF+ L
Sbjct: 180 WSRRRKPEVEFALGIEYMELDSLLSSSDFIFLTMAL 215
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 103 bits (248), Expect = 4e-21
Identities = 70/207 (33%), Positives = 97/207 (46%), Gaps = 1/207 (0%)
Frame = +2
Query: 155 VTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAA 334
V +PE ++ L+ V + + P E LK+ G G K++ E L A
Sbjct: 5 VVYKPLPEETIEYLRSHAQVTIVDPKQPGALIEALKDADGAIGTGV----KMNAETL-AD 59
Query: 335 GPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIH 514
LKV++T+SVG D DV KRG+ + TPDV +RR+ E
Sbjct: 60 ASRLKVLSTVSVGFDAFDVDYLNKRGILLTNTPDVLTESTADTAFSLILLTARRLAELAA 119
Query: 515 EAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS-HRPE 691
K G W G + T+GIVG GRIG +VARR ++Y ++ +
Sbjct: 120 FVKAGKWTKKIAEDRFGVDVHHKTLGIVGLGRIGTSVARRAALGFQMNVLYVDQGVNEKA 179
Query: 692 EKETGAVKVSFDELLTQSDFVICCAXL 772
E+E GA +VSFDELL SDFV+ A L
Sbjct: 180 EREYGAKRVSFDELLKTSDFVLLQAPL 206
>UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1;
Oceanobacillus iheyensis|Rep: 2-ketogluconate reductase
- Oceanobacillus iheyensis
Length = 324
Score = 103 bits (246), Expect = 6e-21
Identities = 62/157 (39%), Positives = 80/157 (50%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++D LLD A P LK+V ISVG+D++++ E KRG+ TPDV
Sbjct: 54 RVDGHLLDQA-PHLKIVTNISVGYDNLEIEELTKRGIMATNTPDVLTDTVADTVFGLLLA 112
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
SRR+ E K G W + G + T+GI+G GRIG AVA R +I+
Sbjct: 113 TSRRICELDQYVKLGRWDENIGEHLFGVDVHHKTLGIIGMGRIGLAVAERAHYGFKMKIV 172
Query: 665 YFNRS-HRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
Y NRS H EK A S +ELLT SDFV+ A L
Sbjct: 173 YHNRSTHSYAEKNINATYASLEELLTVSDFVLVMAPL 209
>UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2;
Alphaproteobacteria|Rep: Glycolate reductase - alpha
proteobacterium HTCC2255
Length = 319
Score = 102 bits (245), Expect = 9e-21
Identities = 56/204 (27%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I++TR + ++ ++ + DV + + P + E++ + I ++ ++++
Sbjct: 5 RIWITRK-LSDATLERAQKDYDVVINLEDQPGTKEEIISASFEFDAIVPCHSEVFSSDVV 63
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
GP LK++A SVG DH D+A ++ + + TPDV +R
Sbjct: 64 SKFGPRLKIIANHSVGVDHCDLAALNEKNILVTNTPDVLSDATAEIAMLLMLGAARHAVL 123
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
++G W +W+P++M G L GA +GI+G GR+GQA A++ + F+ + I YFNR+
Sbjct: 124 GDEIVRSGNWKNWSPSFMVGKQLTGARIGIIGMGRVGQAFAKKARGFDMD-IHYFNRTKL 182
Query: 686 PEEKETGA-VKVSFDELLTQSDFV 754
+ GA + + LL SDF+
Sbjct: 183 NDSVSLGASYHDNIESLLKVSDFL 206
>UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular
organisms|Rep: Glyoxylate reductase - Burkholderia
mallei (Pseudomonas mallei)
Length = 342
Score = 101 bits (242), Expect = 2e-20
Identities = 71/215 (33%), Positives = 104/215 (48%), Gaps = 2/215 (0%)
Frame = +2
Query: 119 RNMSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSL 298
R + +I V R P+ ++ LK DV+ WN + L +A +G +
Sbjct: 7 RGATETAMQKILVARPIFPDV-IERLKQYFDVD-WNDGDALAPDALKARLADKDGALTA- 63
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
D ID +L AA P L+VV+ ++VG+++ D+ V TPDV
Sbjct: 64 GDMIDASVL-AAAPRLRVVSNMAVGYNNFDIGAFDAAHVLGTNTPDVLTETTADFGWALM 122
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
+RR+ E+ H + G W W+ G + GAT+G++G GRIGQA+ARR + F R
Sbjct: 123 MAAARRITESEHWLRAGQWRKWSYDSFLGADIHGATLGVLGMGRIGQALARRARGFGM-R 181
Query: 659 IIYFNRSH-RPE-EKETGAVKVSFDELLTQSDFVI 757
+IY NRS PE E A V LL Q+D V+
Sbjct: 182 VIYHNRSRVAPEIEAALNAEYVPKAALLAQADHVV 216
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 100 bits (240), Expect = 3e-20
Identities = 69/205 (33%), Positives = 101/205 (49%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + E+G+ LK DV++ + + R ELL+ + + I K+D EL+
Sbjct: 2 KIIVTEK-ISENGIDYLKKYADVDV---KTNISREELLEVIKDYDAIIVRSATKVDRELI 57
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+ G LKV+ G D+IDV +RG+ + TP +R +P+
Sbjct: 58 EK-GEKLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQ 116
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A H A G + G L G TVGI+G GRIG VA R+ AFN I Y +
Sbjct: 117 AYHAALNG---DFRRDRFKGVELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAY--DPYM 171
Query: 686 PEEK--ETGAVKVSFDELLTQSDFV 754
P+E+ + G +V+ DELL QSDF+
Sbjct: 172 PDERFEKCGVKRVTLDELLEQSDFI 196
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 99.1 bits (236), Expect = 1e-19
Identities = 57/164 (34%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Frame = +2
Query: 266 VAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXX 445
+A + L++ + LD P+L+V+ T SVG +H+ + C+ RG+RI T V
Sbjct: 57 LASAEALIVLLSEPLTEADLDLC-PNLRVIGTYSVGINHLPITSCQSRGIRIVNTQGVLT 115
Query: 446 XXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAV 625
+RRV E ++G W WAP + G GL G T GI+G G IG+A
Sbjct: 116 DATADLALTLLLSLTRRVREGEALVRSGHWKGWAPDLLLGTGLTGKTCGILGSGPIGRAF 175
Query: 626 ARRVKAFNTERIIYFNRSHRPEEKETG---AVKVSFDELLTQSD 748
ARRV A ++I++NR + + G A ++ DELL QSD
Sbjct: 176 ARRVWAIGM-KVIFWNREGNQKPVDFGVDIAARLPLDELLRQSD 218
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 98.7 bits (235), Expect = 1e-19
Identities = 68/204 (33%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Frame = +2
Query: 155 VTRSDMPESGVQLLKDQCDVNLWNQPSPVPRA--ELLKEVAGVNGIYCSLTDKIDTELLD 328
V+ + + G+ ++D+ + + + P R+ EL+ G + + L D I TE L
Sbjct: 5 VSTRPLIDGGLSGVRDEHTLTVCDPPDGSTRSVDELIALADGADVLLSVLADPI-TEALF 63
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
A P L++V+ +VG D+ID+ + V + +TP V +R VP A
Sbjct: 64 EARPGLQMVSQYAVGVDNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAA 123
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH-R 685
+ G + W T + G LA T+GIVG GRIG AVARR F E +IY NR+
Sbjct: 124 DRYVRDGRFERWETTHLMGMELARKTIGIVGMGRIGTAVARRALGFGME-VIYHNRTRAN 182
Query: 686 PE-EKETGAVKVSFDELLTQSDFV 754
P E++ A V ELLT SD V
Sbjct: 183 PTVERQVSARHVGLGELLTTSDVV 206
>UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1;
Bacillus subtilis|Rep: Probable 2-ketogluconate
reductase - Bacillus subtilis
Length = 325
Score = 98.3 bits (234), Expect = 2e-19
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 3/206 (1%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTD--KIDTEL 322
+++T+ +PE + + C +W Q +P L +++ G+ S T I+ EL
Sbjct: 6 VFITKP-IPEEIEAFIGEHCRYEVW-QEDTLPSDVLFEKLKEAEGLLTSGTSGPSINREL 63
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
L+ A P LKVV+ SVG+D+ D+ K+RGV +TP +RRV
Sbjct: 64 LEHA-PKLKVVSNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVA 122
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
E + G W + + G + T+GI+G GRIG+ ARR K ++Y NR
Sbjct: 123 ELDRFVRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHR 182
Query: 683 RPEEKETGAVK-VSFDELLTQSDFVI 757
+ E +++ VK D LL QSDF++
Sbjct: 183 KQETEDSIGVKYAELDTLLEQSDFIL 208
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/208 (31%), Positives = 98/208 (47%), Gaps = 7/208 (3%)
Frame = +2
Query: 152 YVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDA 331
Y+ + +PE G+QLL D V + P L + + L D ID LL
Sbjct: 5 YLVTTAIPEPGLQLLSDAGQVTVLPDPPDYATLAALCASGDYDVVLTQLRDVIDEPLL-- 62
Query: 332 AGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAI 511
A +K V+ +VG+++IDV + G+ +G TP V +RRV E+
Sbjct: 63 ANARVKGVSNYAVGYNNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESD 122
Query: 512 HEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN-RSHRP 688
+ G ++ W P +M G ++GA +G+ GFGRI +AVARR F E + RP
Sbjct: 123 RVVRDGKFLGWEPEFMLGRDVSGAVLGLAGFGRIARAVARRALGFGMEELFSPRPPGDRP 182
Query: 689 EEKE-----TGAVK-VSFDELLTQSDFV 754
E G V+ V +D L+ +SDF+
Sbjct: 183 VSDEELGEFAGKVRQVPWDSLVERSDFL 210
>UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8;
Alphaproteobacteria|Rep: Glycolate reductase -
Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Length = 323
Score = 97.5 bits (232), Expect = 3e-19
Identities = 62/207 (29%), Positives = 101/207 (48%), Gaps = 3/207 (1%)
Frame = +2
Query: 137 GRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAEL--LKEVAGVNGIYCSLTDKI 310
G+ + VTR+ +P + + L DV L P+P +L L G + + TD++
Sbjct: 3 GKPVVLVTRT-LPAAVEERLLGDYDVWLNRDDRPIPPEDLPALARRLGAQAMLVTPTDRL 61
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
+ +++A S+ ++A+ SVG++HID +RG+ + TP V +
Sbjct: 62 ERAVIEALPNSVAIIASFSVGYEHIDHNAAARRGILVTNTPGVLSDATADIALLLMLGAA 121
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYF 670
RR E ++G W P + G L G +GI+G GRIGQA+A R + E I Y
Sbjct: 122 RRASEGERLVRSGYWKGLTPVQLLGRHLHGQRLGILGMGRIGQALAERARPLGLE-IHYH 180
Query: 671 NRSHRPEEKETGAV-KVSFDELLTQSD 748
NR+ E+ GA+ + ++LL SD
Sbjct: 181 NRTPIAEDAAKGAIFHATVEDLLAVSD 207
>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
AMMD)
Length = 320
Score = 97.1 bits (231), Expect = 4e-19
Identities = 55/150 (36%), Positives = 76/150 (50%), Gaps = 1/150 (0%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+ E + A PS+K++A S G+DH+DVA ++RG+ + PD
Sbjct: 61 LQAEHIAALPPSVKIIANASAGYDHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAA 120
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
RR E + G S+ T M G + G T+GIVGFGRIG+AVA+R + F +I+Y
Sbjct: 121 CRRASEYERIVRAGWGKSFGMTDMLGTRVNGKTLGIVGFGRIGRAVAQRARGFGM-KIVY 179
Query: 668 FNRSHRPEEKETGA-VKVSFDELLTQSDFV 754
+R P E E GA D LL Q D V
Sbjct: 180 TDRQPAPPEVEAGARYCADLDTLLPQCDIV 209
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 97.1 bits (231), Expect = 4e-19
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +2
Query: 251 ELLKE-VAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGY 427
+LLK+ + + K+D EL+DAA P LK++A G D++D ++G+ + +
Sbjct: 35 DLLKQKIQNTRALIVRNQTKVDRELIDAA-PELKIIARAGAGLDNVDTEYAHEKGIVVCF 93
Query: 428 TPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFG 607
TPD R++PEA + TGGW TG L G + G++G G
Sbjct: 94 TPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWNRLK---FTGTELYGKSFGLIGLG 150
Query: 608 RIGQAVARRVKAFNTERIIY--FNRSHRPEEKETGAVKVSFDELLTQSDFVIC 760
RIG A R KAF + F ++ P+ K+ A +S D+LL +SD V C
Sbjct: 151 RIGSFTATRAKAFGMNILAADPFLKADAPQLKKLNATLLSLDDLLAESDVVSC 203
>UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pseudomonas putida
W619|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas putida W619
Length = 318
Score = 96.7 bits (230), Expect = 6e-19
Identities = 63/177 (35%), Positives = 86/177 (48%), Gaps = 1/177 (0%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
R L +A +G+ S T +D ELLD A PSLKV+A++S G D+ + + RG+ +
Sbjct: 35 RDGFLAALATADGLIGS-TLPLDAELLDHA-PSLKVIASVSAGFDNYPLGYLRDRGICLT 92
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TPD +RR E + GGW G + G T+GIVG
Sbjct: 93 NTPDAVTETTADTGFMLLMMAARRACELAQLVRDGGWTQGIDASRFGMDVHGKTLGIVGL 152
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPE-EKETGAVKVSFDELLTQSDFVICCAXL 772
GRIG AVARR ++Y S +PE E E A +V +LL ++DFV C L
Sbjct: 153 GRIGAAVARRAHFGFGMPVLYSGNSAKPEYEAEFAARRVPLMQLLGEADFVCVCVPL 209
>UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3;
Cyanobacteria|Rep: Glycerate dehydrogenase - Anabaena
sp. (strain PCC 7120)
Length = 332
Score = 96.3 bits (229), Expect = 7e-19
Identities = 59/205 (28%), Positives = 97/205 (47%), Gaps = 1/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++ +T PE ++LLK C+V + R E+L+ + + D ID L
Sbjct: 4 KVVITNWVHPEV-IELLKPSCEVIANPSKEALSREEILQRAKDAEALMVFMPDTIDEAFL 62
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
P LK++A G+D+ DVA C RG+ P + R++ E
Sbjct: 63 REC-PKLKIIAAALKGYDNFDVAACTHRGIWFTIVPSLLSAPTAEITIGLLIGLGRQMLE 121
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
+TG + W P + + GLA T+GIVG G +G+A+A R+ F + + +
Sbjct: 122 GDRFIRTGKFTGWRPQFYS-LGLANRTLGIVGMGALGKAIAGRLAGFEMQLLYSDPVALP 180
Query: 686 PEEKETGAV-KVSFDELLTQSDFVI 757
PE++ TG + +V F+ L+ SDFV+
Sbjct: 181 PEQEATGNISRVPFETLIESSDFVV 205
>UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=2; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 322
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/209 (29%), Positives = 103/209 (49%), Gaps = 1/209 (0%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++ TR D+ G++LLK D+ L ++P+ +PR E +++ + IY D I+ E+L
Sbjct: 12 VFCTR-DVKPGGMELLKKHFTDIILPSKPNGIPREEFIEKAKKADIIYADRRDVINKEIL 70
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
D P LK++ + G+D+ID+ KR + + T +RRV E
Sbjct: 71 D--NPKLKLITVCAAGYDNIDINYATKRKIIVANTHKSLADTCADTIWSLIMACARRVVE 128
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A K G W +P + G + T+G++G G IG+AVA+R + FN + + FN
Sbjct: 129 ADQFVKNGDWEKTSPQCLWGINVHHKTLGVIGAGHIGRAVAKRGEGFNMK--VLFN---- 182
Query: 686 PEEKETGAVKVSFDELLTQSDFVICCAXL 772
+TG ++LL +SD V+ L
Sbjct: 183 ----DTGPQYTPLEQLLKESDVVVVACPL 207
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 94.3 bits (224), Expect = 3e-18
Identities = 60/205 (29%), Positives = 107/205 (52%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + +P+ G++ L D+ DV +++ P R +L+ ++ +G + + K D E++
Sbjct: 5 KILVTGT-VPKEGLRKLMDRFDVT-YSEDRPFSRDYVLEHLSEYDG-WLLMGQKGDKEMI 61
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
DA G +L++++ +VG DH+D A K++G+ + +P S+R+
Sbjct: 62 DA-GENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLAF 120
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
++G W+ + G L G+T+GI G GRIG VA KAF ++Y +
Sbjct: 121 YDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIGLTVANFAKAFGM-TVVYNDVYRL 179
Query: 686 PE--EKETGAVKVSFDELLTQSDFV 754
PE EKE G + FD+L+ +D +
Sbjct: 180 PEDKEKELGVTYLEFDQLIKTADVI 204
>UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2;
Filobasidiella neoformans|Rep: Glyoxylate reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 345
Score = 93.5 bits (222), Expect = 5e-18
Identities = 52/145 (35%), Positives = 75/145 (51%), Gaps = 8/145 (5%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
+DK+D EL+ A +L+ +++ SVG+DHIDV RG++IG+TP V
Sbjct: 59 SDKVDKELIATANDNLRCISSFSVGYDHIDVKAANARGIKIGHTPGVLSDAVADIAVILV 118
Query: 479 XXXSRRVPEAIHEAKTGGWVS--WAPTWMTG--PGLAGATVGIVGFGRIGQAVARRVKAF 646
RR+ E I+ K+G W WAP G G T+G +GFGRI QA +R+ AF
Sbjct: 119 LSTLRRIGEGINLVKSGNWKQQPWAPFVNCGLSIGHPSLTIGFLGFGRISQATVQRLLAF 178
Query: 647 NTE----RIIYFNRSHRPEEKETGA 709
+ RI+Y + R + E A
Sbjct: 179 TNKEQPPRILYTSSYRRDNQDEIDA 203
>UniRef50_Q7PMI6 Cluster: ENSANGP00000021069; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000021069 - Anopheles gambiae
str. PEST
Length = 311
Score = 93.1 bits (221), Expect = 7e-18
Identities = 66/210 (31%), Positives = 105/210 (50%), Gaps = 2/210 (0%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGI-YCSLTDKIDT 316
R ++ VT + +Q L+ CDV + P RA++L GV+G+ + S K+D
Sbjct: 5 RPRVLVTHHQVQPVALQRLRKDCDVIVPAVDFP-SRAQILDLCPGVDGLLWTSYKMKLDR 63
Query: 317 ELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRR 496
E+LDA G LK ++ G D +DV E +R + +G+TP + + R
Sbjct: 64 EVLDACGAQLKAISLTMNGVDCVDVKELARRNIPLGHTPYIPNRAVADLAVGLMLSVNER 123
Query: 497 VPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
+ T G + + P + G+T+GIVGFG IGQ +A R++AF+ + I+Y
Sbjct: 124 L------LSTAGEI----CYQRQP-IQGSTIGIVGFGGIGQLIASRLQAFDVDCILYCGP 172
Query: 677 SHRPEEKETGAVKVSFDELLTQSDFV-ICC 763
+ A V+F++LL +SDFV I C
Sbjct: 173 RPKASADAFHAQFVAFEQLLVRSDFVFISC 202
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 92.7 bits (220), Expect = 9e-18
Identities = 60/178 (33%), Positives = 88/178 (49%), Gaps = 8/178 (4%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
R EL +++A + I SL+D +D E++ G +LKV+ + G ++ID+ K+ GV +
Sbjct: 33 RQELSRQIATADAILTSLSDPLDAEMI-GQGKNLKVIGQCAAGFNNIDLDAAKQAGVVVT 91
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP V +RR EA + G + T+M G GL GAT+GIVG
Sbjct: 92 STPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIVGL 151
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAV--------KVSFDELLTQSDFV 754
G+IG+A+ARR AF + +N H + AV +V DEL SD V
Sbjct: 152 GQIGEAMARRGAAFGMN--VIYNARHEKDVAAIDAVNLNTQPTRRVELDELFATSDVV 207
>UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospirillum
gryphiswaldense|Rep: Glycolate reductase -
Magnetospirillum gryphiswaldense
Length = 330
Score = 92.7 bits (220), Expect = 9e-18
Identities = 50/155 (32%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Frame = +2
Query: 293 SLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXX 472
+LTD+++ +DA S++++ T SVG +H+D+ ++ G+ + Y P+
Sbjct: 64 TLTDRLEATTIDALPASVRIICTYSVGTNHLDLQAARRHGIALAYAPEAVTEATADTAML 123
Query: 473 XXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
RR E + + G W +W G G +G+VG GRIG+AVARR +AF
Sbjct: 124 LLLAACRRAHEFQAQLRQGRWGAWNAWENLGWDPGGQILGLVGMGRIGRAVARRARAFGM 183
Query: 653 ERIIYFNRSHRPEEKETGAV-KVSFDELLTQSDFV 754
+ I YF R+ E GA S D L S FV
Sbjct: 184 D-IHYFQRNRLESSLEDGATYHSSLDSLFAISRFV 217
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 92.3 bits (219), Expect = 1e-17
Identities = 63/195 (32%), Positives = 91/195 (46%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+ +S V L DQ +V + P R +LL V + + +D E+L AA P LK
Sbjct: 12 LAQSTVAALGDQVEVRWVDGPD---RTKLLAAVPEADALLVRSATTVDAEVL-AAAPKLK 67
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTG 529
+VA VG D++DV RGV + P SR++ EA +A
Sbjct: 68 IVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEA--DASLR 125
Query: 530 GWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGA 709
+ W + +G + G TVG+VG GRIGQ VA R+ AF I Y + G
Sbjct: 126 AHI-WKRSSFSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGI 184
Query: 710 VKVSFDELLTQSDFV 754
+SFD+LL ++DF+
Sbjct: 185 ELMSFDDLLARADFI 199
>UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1;
Bdellovibrio bacteriovorus|Rep: Hxdroxypyruvate
reductase - Bdellovibrio bacteriovorus
Length = 319
Score = 91.9 bits (218), Expect = 2e-17
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 1/151 (0%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
KI E++ A S+K++AT SVG DH+D+A K+RG+ + TPDV
Sbjct: 56 KITAEVIKALPDSVKIIATSSVGFDHLDIAAAKERGILLSNTPDVLTECTADLGMMLLLN 115
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
RR E + + G +++ T M G ++G T+GI+G GRIG+A+A R + F +II
Sbjct: 116 ACRRGREYLSIMQEGWRKTYSQTDMLGLQVSGRTLGILGMGRIGRALADRARGFGM-KII 174
Query: 665 YFNRSHRPEEKETGAVKV-SFDELLTQSDFV 754
Y N P E E AV +F ++L +
Sbjct: 175 YCNNKRLPPELEKDAVYFKNFHDMLPHCQII 205
>UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 320
Score = 91.9 bits (218), Expect = 2e-17
Identities = 58/161 (36%), Positives = 87/161 (54%), Gaps = 4/161 (2%)
Frame = +2
Query: 284 IYCSLTD-KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXX 460
+ CS+ D ++ EL+D A LK+VA +VG+++IDVA C ++G+ + TPD
Sbjct: 46 VLCSMFDFPVNKELIDHAS-KLKMVANYAVGYNNIDVAYCLEKGITVANTPDPVTAPTAN 104
Query: 461 XXXXXXXXXSRRVPEAIHEAKTGG-WVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRV 637
+RR+ E + + G + G + G T+GI+G GRIG+A+ARR
Sbjct: 105 LALGLMLDVARRITECDRKLRREGLGMKVGVLENLGINVTGKTLGIIGMGRIGKALARRA 164
Query: 638 KAFNTERIIYFNRSHRPEEKET--GAVKVSFDELLTQSDFV 754
A E ++Y NR E+ET VS +ELL+QSDFV
Sbjct: 165 NACGME-VLYHNRRQLYVEEETKLNVTYVSKEELLSQSDFV 204
>UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase - Rhodobacterales bacterium
HTCC2654
Length = 301
Score = 91.1 bits (216), Expect = 3e-17
Identities = 53/157 (33%), Positives = 73/157 (46%)
Frame = +2
Query: 242 PRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRI 421
P +E+ + A +G+ S+ +D+ + L V T SVG DHID A +RG+ +
Sbjct: 15 PLSEVTAKDAA-DGLVLSVETPLDSAAIARLPAGLAAVGTYSVGTDHIDRAALAERGIAL 73
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
TPDV RR E+I ++G W W P + G LA T GI G
Sbjct: 74 LSTPDVLSASVAEIAVFLTLGAMRRATESISLVRSGAWTGWTPGQLLGHELASRTAGIFG 133
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAV 712
GRIG+ +A R+ I Y NRS + E GAV
Sbjct: 134 MGRIGREIAARLSGMGM-TIAYHNRSRLKPKDERGAV 169
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 90.6 bits (215), Expect = 4e-17
Identities = 68/202 (33%), Positives = 95/202 (47%), Gaps = 6/202 (2%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAG-VNGIYCSLTDKIDTELLDAAGPSL 346
M ++ LK DV L P P E LKE+ ++GI + +I ++L+ A L
Sbjct: 11 MKSKPLEELKKYTDVVL----KPYPSEEELKEIIPELDGIIIAPVTRITKDILERA-ERL 65
Query: 347 KVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKT 526
KV++ S G+DH+DV E KRG+ + + R++ A +
Sbjct: 66 KVISCQSAGYDHVDVEEATKRGIYVTKVSGLLSEAVAEFALGLLISLMRKIHYADSFIRE 125
Query: 527 GGWVSWAPTWMTGPG---LAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE-- 691
G W S W L G VGIVG G IG+A+ARR+K F E IY+ HR E
Sbjct: 126 GKWESHTFVWREFKEVETLYGKEVGIVGMGAIGKAIARRLKPFGCE--IYYWSRHRKEDI 183
Query: 692 EKETGAVKVSFDELLTQSDFVI 757
E+E A + DELL + D VI
Sbjct: 184 EREVNAKYLDLDELLEEVDIVI 205
>UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidobacteria bacterium
Ellin345|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Acidobacteria bacterium
(strain Ellin345)
Length = 371
Score = 89.4 bits (212), Expect = 9e-17
Identities = 54/184 (29%), Positives = 98/184 (53%), Gaps = 3/184 (1%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVA-GVNGIYCSL 298
MS K +++++ T D+ + ++ L+ DV ++ Q P P++ ++++VA G++G+ +L
Sbjct: 1 MSGK-KFRVFAT-CDIGKPALERLRAAGYDVEVYPQADPPPKSLIIEKVASGIDGLITTL 58
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
DKID E+ +A +LKVVA I+VG D+I+ A+ K V +T DV
Sbjct: 59 RDKIDAEVFEAGKGNLKVVAQIAVGFDNINRADANKYKVPFTHTADVLTEATAEFAFFIM 118
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTW-MTGPGLAGATVGIVGFGRIGQAVARRVKAFNTE 655
+R++ A + W +W P G + G ++ I+G GRIG A+ ++ F+
Sbjct: 119 AAAARKLWTAERNVRDLKWGTWHPFLPFLGDEVTGKSIAIIGTGRIGLAMIKKCSGFDMN 178
Query: 656 RIIY 667
+ Y
Sbjct: 179 ILCY 182
>UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=8; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 335
Score = 89.4 bits (212), Expect = 9e-17
Identities = 66/210 (31%), Positives = 99/210 (47%), Gaps = 5/210 (2%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R +I V R ++P + L+ +V + N P A +A +G+ S + I
Sbjct: 10 RKKILVFR-ELPPDQLARLQAMHEVTVANPRLPGQLAAFHAALASADGMIGS-SYAITAS 67
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
LL A+ P LKV++++SVG D+ D+ RG+ + +TP V SRR+
Sbjct: 68 LL-ASAPQLKVISSVSVGVDNYDLPALAARGIMLCHTPGVLTETTADTIFSLIMASSRRL 126
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR- 676
E + G W + G + G T+GI+GFGRIGQAVARR ++Y +R
Sbjct: 127 VELASHVREGRWTRNIGEDLFGWDVHGKTLGILGFGRIGQAVARRAALGFNMPVLYHSRR 186
Query: 677 ----SHRPEEKETGAVKVSFDELLTQSDFV 754
+H E A FDELL ++D V
Sbjct: 187 PVDVAHELPELAGKATHTPFDELLQRADIV 216
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 89.4 bits (212), Expect = 9e-17
Identities = 57/194 (29%), Positives = 96/194 (49%)
Frame = +2
Query: 173 PESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKV 352
P G+ + K D ++ N P + R ELLK++ + I KID +++D A LK+
Sbjct: 10 PVDGIMIEKLSKDFDIDNSPD-ITRDELLKKIGDYDIIIVRSRTKIDRDIIDNA-KRLKI 67
Query: 353 VATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGG 532
+A +G D IDV +++G++I Y P +R++ + + +
Sbjct: 68 IARAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENTRKND 127
Query: 533 WVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAV 712
+ T + G L+G T+GI+G+GRIG+A+A FN I Y P + TGA
Sbjct: 128 F-----TKLKGIELSGKTLGIIGYGRIGRAIANAFSVFNVRSIAY---DAYPVD-FTGAE 178
Query: 713 KVSFDELLTQSDFV 754
+V+ ++LL SD +
Sbjct: 179 QVTLEDLLRNSDII 192
>UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase;
n=1; Desulfotignum phosphitoxidans|Rep: Putative
2-hydroxy acid dehydrogenase - Desulfotignum
phosphitoxidans
Length = 354
Score = 89.0 bits (211), Expect = 1e-16
Identities = 60/211 (28%), Positives = 99/211 (46%), Gaps = 4/211 (1%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++Y T +P ++LLK C+V N + E+++ + + C + D ID E++
Sbjct: 19 RVYYTHK-IPSEAIKLLKLFCEVIEHNNFESPTKKEIIRNSRNADVLCCFVPDCIDEEII 77
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
A+ P L+++A+ + GHD I+V RG+ + +R +
Sbjct: 78 -ASCPQLRIIASCAAGHDGINVPAATMRGIWVTIVNAETIEPTADLTWALLLSSARGIVP 136
Query: 506 AIHEAKTGGWVSWA-PTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
A ++G W P +G + G T+GI+G G +G+A+ARR FN I Y + H
Sbjct: 137 ADFFVRSGDLKGWCQPPPFSGQNIFGKTLGIIGMGSLGRAIARRAVGFNMTSIYY--QRH 194
Query: 683 RPEEKETGAVKVS---FDELLTQSDFVICCA 766
R E K +K+ +EL SDF IC A
Sbjct: 195 RLEVKYEQDLKIENVVLEELFKTSDF-ICIA 224
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 88.2 bits (209), Expect = 2e-16
Identities = 56/205 (27%), Positives = 101/205 (49%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
RY+++V + + QLL ++ ++ + ++ + + EL+K + V+ + K+ +
Sbjct: 3 RYRVHVN-DPLDKEATQLLMNKEELEVTSEH--LEKDELMKIIPEVDVLVVRSATKVTAD 59
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+++A G +LK++A +G D+IDV + K++G+++ TP +R +
Sbjct: 60 IIEA-GKNLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHI 118
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
A K G W A + G L G T+G++GFG IGQ VA+R AF + I Y
Sbjct: 119 ARATVSLKEGKWEKKA---LKGKELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAY---D 172
Query: 680 HRPEEKETGAVKVSFDELLTQSDFV 754
E + V D L +SDF+
Sbjct: 173 PAKPETDLPVEYVDLDTLFKESDFI 197
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQ---LLK-DQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDK 307
+Y++ +T ES + +LK + C+V P+ EL+ V + + DK
Sbjct: 3 KYKVVITARSFGESSDEPFNILKGNDCEVVKIPVDRPLSAEELIPLVKDADALIVG-NDK 61
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+ ++++A G LKV++ VG+D++D+ KK+G+ + TP+
Sbjct: 62 VTEDVINA-GKKLKVISRYGVGYDNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVL 120
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
+R + K+GGW + G + G T+GI+G G+IG+ VA+R K F+ + Y
Sbjct: 121 ARNLLAVDRIVKSGGWKR-----IMGTEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCY 175
Query: 668 FNRSHRPEEKETGAVKVSFDELLTQSDFV 754
+E G SF+ELL QSD V
Sbjct: 176 DVYPDLKFSEEYGVTYCSFEELLKQSDIV 204
>UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 332
Score = 88.2 bits (209), Expect = 2e-16
Identities = 58/168 (34%), Positives = 84/168 (50%), Gaps = 13/168 (7%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+D+ L+D P L+V+++ VG DHID+A RG+R+G TP V
Sbjct: 59 VDSALMDCY-PELRVISSAGVGVDHIDLAAATIRGIRVGNTPGVVQECTADHAIGLLLAS 117
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
+R++ + G+ + G + G+T+GIVG G +G AVA R K F RI+Y
Sbjct: 118 ARKICSGDSVIRQPGFSKESIFNSFGTKVTGSTLGIVGLGGVGSAVANRAKGFKM-RILY 176
Query: 668 FNRSHRPEEKETGAVKVSF-------------DELLTQSDFVICCAXL 772
NR+ R E+KE V + F DELL +SDFV+ C L
Sbjct: 177 HNRT-RKEDKELETVVLLFYYAFVGAEYCSKLDELLKESDFVVLCCAL 223
>UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase
UNK4.10; n=14; Dikarya|Rep: Putative 2-hydroxyacid
dehydrogenase UNK4.10 - Schizosaccharomyces pombe
(Fission yeast)
Length = 334
Score = 87.8 bits (208), Expect = 3e-16
Identities = 47/146 (32%), Positives = 74/146 (50%)
Frame = +2
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D E++D PS+K + + G++ +DVA C RG+++ + P
Sbjct: 70 DKEIIDNLPPSVKFICHLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGAL 129
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYF 670
R + I E +W G T+GI+G G IG+ +A+R +AF+ +I+Y
Sbjct: 130 RGFNQGIFELHKN---NWNANCKPSHDPEGKTLGILGLGGIGKTMAKRARAFDM-KIVYH 185
Query: 671 NRSHRPEEKETGAVKVSFDELLTQSD 748
NR+ PEE+ GA VSFD+LL +SD
Sbjct: 186 NRTPLPEEEAEGAEFVSFDDLLAKSD 211
>UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75;
Proteobacteria|Rep: 2-ketogluconate reductase -
Escherichia coli O157:H7
Length = 324
Score = 87.8 bits (208), Expect = 3e-16
Identities = 62/197 (31%), Positives = 89/197 (45%), Gaps = 2/197 (1%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+P+ +Q L++ V+ SP + A G+ S + +D LL+ P L+
Sbjct: 11 LPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGS-NENVDAALLEKM-PKLR 68
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTG 529
+TISVG+D+ DV R + + +TP V +RRV E K G
Sbjct: 69 ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128
Query: 530 GWV-SWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVK-AFNTERIIYFNRSHRPEEKET 703
W S P W G + T+GIVG GRIG A+A+R FN + R H+ E+
Sbjct: 129 EWTASIGPDWY-GTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERF 187
Query: 704 GAVKVSFDELLTQSDFV 754
A D LL +SDFV
Sbjct: 188 NARYCDLDTLLQESDFV 204
>UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Rep:
Im:7137941 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 337
Score = 87.4 bits (207), Expect = 3e-16
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 3/158 (1%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+D +LL + P+LK V VG DH+D+ GV++ TP V
Sbjct: 73 VDRDLLQSL-PNLKAVINGGVGVDHLDIPLINSFGVKVSNTPHVVDNATADIGMSLMLAS 131
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
+R++ E H +K + + M G ++GAT+GI+G GRIG +A+R + F+ +I+Y
Sbjct: 132 ARKIIEGQHFSKFRESDDFPESTM-GTDVSGATLGIIGMGRIGYKIAKRAQGFDM-KILY 189
Query: 668 FNRSHRP--EEKETGAVK-VSFDELLTQSDFVICCAXL 772
NR+ RP EE+ GA S ELL +SDFV+ L
Sbjct: 190 HNRNRRPENEERAVGATYCASMTELLQRSDFVMVVVNL 227
>UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Bacteroidetes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Flavobacterium johnsoniae UW101
Length = 325
Score = 86.6 bits (205), Expect = 6e-16
Identities = 62/198 (31%), Positives = 96/198 (48%), Gaps = 4/198 (2%)
Frame = +2
Query: 167 DMPESGVQLLKDQCDVNLWNQPSP--VPRAELLKEVAGVNGIYCSL-TDKIDTELLDAAG 337
++PE+G++LL+++ +NL P+ + R + +K + N + ++ T E
Sbjct: 8 NIPEAGLRLLQEK-GINLTINPTENVLSREDFIK-ICQKNDVLLNVGTQNFFDEDFFQQC 65
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P+LK +A SVG D +++ R + IG TPDV +R+
Sbjct: 66 PNLKGIALFSVGFDSVNIPSANSRKIPIGNTPDVLSRATSDVSFLLMQSVARKSFFNHKR 125
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE-E 694
W S+ P G L G T+GI G GRIG +A++ KA IIY NRS + + E
Sbjct: 126 ILNNDWGSFDPLANLGQELYGKTLGIFGLGRIGFKMAQKCKAAFGMNIIYHNRSRKEDAE 185
Query: 695 KETGAVKVSFDELLTQSD 748
KE A V F+ LL +SD
Sbjct: 186 KELDAKYVDFETLLAESD 203
>UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16;
Bacteria|Rep: Phosphonate dehydrogenase - Pseudomonas
stutzeri (Pseudomonas perfectomarina)
Length = 336
Score = 86.6 bits (205), Expect = 6e-16
Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 1/192 (0%)
Frame = +2
Query: 185 VQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATI 364
+QLL C++ S + R E+L+ + + D++D + L A P L+VV
Sbjct: 16 LQLLAPHCELMTNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQAC-PELRVVGCA 74
Query: 365 SVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSW 544
G D+ DV C RGV + + PD+ R + A ++G + W
Sbjct: 75 LKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGW 134
Query: 545 APTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS-HRPEEKETGAVKVS 721
P + G GL ATVGI+G G IG A+A R++ + + ++ E+ G +V+
Sbjct: 135 QPQFY-GTGLDNATVGILGMGAIGLAMADRLQGWGATLQYHEAKALDTQTEQRLGLRQVA 193
Query: 722 FDELLTQSDFVI 757
EL SDF++
Sbjct: 194 CSELFASSDFIL 205
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 86.2 bits (204), Expect = 8e-16
Identities = 60/206 (29%), Positives = 98/206 (47%), Gaps = 2/206 (0%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
Y++ V+ + P+ G+++L+ + DV P + R E L + +G+ ++D E
Sbjct: 2 YKVLVSDNISPK-GIEILEQEADVTF--NPD-LSREEFLDIIGEYDGLIVRSMTEVDKEA 57
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
LD A +LKV+ G+D+ID+ E KRG+ + TP SR +P
Sbjct: 58 LDKAR-NLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIP 116
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
+A G W G + G T+GI+G GRIG VA R +AF + + N +
Sbjct: 117 QANQALHEG---IWDRKKYMGVEVKGKTLGIIGLGRIGSRVAVRAQAFGMK--VIANDPY 171
Query: 683 RPEEK--ETGAVKVSFDELLTQSDFV 754
P EK + + F E+L +SD++
Sbjct: 172 LPPEKAAKINVPLLGFKEVLKKSDYI 197
>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Silicibacter sp. (strain TM1040)
Length = 322
Score = 86.2 bits (204), Expect = 8e-16
Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 1/195 (0%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTD 304
M+A R ++ +TR M + + + DV + + +P+ E+ + + + + +L D
Sbjct: 1 MAASERRRLLITRP-MTAAVEARARAELDVEIRQETTPLSPEEMRQSLGAFDLVMPTLGD 59
Query: 305 KIDTELLDAAG-PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
++ A P +++A VG +HID + GV + TP
Sbjct: 60 AYSADVFAAVPQPRCRLLANFGVGFNHIDAEAARAAGVEVTNTPGAVTDATADIALTLML 119
Query: 482 XXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERI 661
+RR E ++G W W PT M G L+G +G+VG GRIG A+ARR I
Sbjct: 120 MTARRAGEGERLVRSGQWQGWHPTQMLGLHLSGKRLGVVGLGRIGDAIARRAHFGFGMEI 179
Query: 662 IYFNRSHRPEEKETG 706
Y RS +KETG
Sbjct: 180 SYLARS----DKETG 190
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 85.4 bits (202), Expect = 1e-15
Identities = 62/192 (32%), Positives = 98/192 (51%), Gaps = 5/192 (2%)
Frame = +2
Query: 194 LKDQCDVNLW---NQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATI 364
L+ C+V + ++P+ R +LK +A +G+ + D E++DAA +LKV++T
Sbjct: 20 LRSTCEVTVGPVGHRPND-DRQWVLKNIAKYDGVIVAKMI-FDKEIIDAA-KNLKVISTY 76
Query: 365 SVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSW 544
VG DHID+ +++G+ + P+ +RR+ H + G +++
Sbjct: 77 GVGFDHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNV 136
Query: 545 APTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH-RPE-EKETGAVKV 718
G + G T+GI+G GRIGQ VAR KA +IIY NR +PE E E A V
Sbjct: 137 DEYDSQGYTIEGKTLGILGMGRIGQQVARFAKALGM-KIIYHNRHQLKPELEAELNARYV 195
Query: 719 SFDELLTQSDFV 754
F L+ SDF+
Sbjct: 196 DFASLVKNSDFL 207
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 1/206 (0%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
+++I + S M G ++L ++C++ + + L+ + A V+GI +
Sbjct: 4 KFKILLYES-MHARGTEVLAEKCELVY---ATSLDEKNLIAQAADVDGIIIRANGAVTRA 59
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
L+++A P LKV+ VG D ID+ K+RGV++ +TP ++ +
Sbjct: 60 LIESA-PRLKVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMI 118
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
+TG W A + G L G +G++GFGRIG+ AR + +IY++
Sbjct: 119 RTGDIALRTGDWA--ARNRLIGTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYDVC 176
Query: 680 HRPE-EKETGAVKVSFDELLTQSDFV 754
P EKE A +VS +E+ QSDF+
Sbjct: 177 DYPAVEKELQAKRVSGEEVFEQSDFI 202
>UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1;
Colwellia psychrerythraea 34H|Rep: Putative glyoxylate
reductase - Colwellia psychrerythraea (strain 34H / ATCC
BAA-681) (Vibriopsychroerythus)
Length = 311
Score = 85.0 bits (201), Expect = 2e-15
Identities = 52/161 (32%), Positives = 80/161 (49%), Gaps = 4/161 (2%)
Frame = +2
Query: 284 IYCSLT-DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXX 460
+ CS + D +D + S+K++A I VG+D+ID+A +G+ + TP V
Sbjct: 40 VICSTSLDALDHNFITQLPESIKLIANIGVGYDNIDLAAATAKGIAVTNTP-VVTEDTAD 98
Query: 461 XXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVK 640
SR++ + G W + P G + GA +GI+GFG IGQAVARR K
Sbjct: 99 LAFSLILAASRQLTANEKFLRNGQWSATNPIGCLGKTVHGAKLGIIGFGEIGQAVARRAK 158
Query: 641 AFNTERIIYFNRSHRPEEKETGAVKVSFD---ELLTQSDFV 754
AFN E I+++ R + E V F+ ++L SD +
Sbjct: 159 AFNME--IFYHGPRRKIDAEVSLEAVYFENLTDMLAASDII 197
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 85.0 bits (201), Expect = 2e-15
Identities = 50/170 (29%), Positives = 76/170 (44%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
R EL++EV I K+D E++ AA +LK++ VG D+ID+ +RG+ +
Sbjct: 32 REELIREVPKYEAIVVRSQTKVDAEVIQAA-KNLKIIGRAGVGVDNIDINAATQRGIVVV 90
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
P +R++P+A K G W G L G T G++G
Sbjct: 91 NAPGGNTISTAEHAIALMLAAARKIPQADRSVKEG---KWERKKFMGIELRGKTAGVIGL 147
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GR+G VA+R KA + Y + ++ G V FD LL SD +
Sbjct: 148 GRVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGVKLVDFDTLLASSDVI 197
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 84.6 bits (200), Expect = 2e-15
Identities = 47/133 (35%), Positives = 72/133 (54%), Gaps = 3/133 (2%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L+++++ VG+D +DV K+ GVR+ TPDV + RVPE+
Sbjct: 66 PDLEIISSFGVGYDAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAY 125
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS---HRP 688
+ G W + +T L GATVGI+G GRIG+A+AR +AF+ R++Y RS H+P
Sbjct: 126 VRDGRWETEGAMPLTAE-LTGATVGIIGLGRIGKAIARLAQAFSM-RVVYHGRSEQAHQP 183
Query: 689 EEKETGAVKVSFD 727
+ V ++ D
Sbjct: 184 YQYYADPVAMARD 196
>UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3;
Alphaproteobacteria|Rep: 2-hydroxyacid dehydrogenase -
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 311
Score = 84.2 bits (199), Expect = 3e-15
Identities = 52/146 (35%), Positives = 74/146 (50%)
Frame = +2
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P+L++VA VG D +D+ E K+RG R+ TPDV +R+VP+A
Sbjct: 62 AALPNLEIVAINGVGFDKVDLGEAKRRGFRVSNTPDVLTADVADLALGLVLAQARKVPQA 121
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
+TG W+ T +AG GI G GRIGQA+A+R++ F+ RI Y R+ R
Sbjct: 122 DQHVRTGQWLKGDMGLST--RVAGRRYGIFGLGRIGQAIAKRLEGFDA-RISYTARNRRD 178
Query: 689 EEKETGAVKVSFDELLTQSDFVICCA 766
+ S +EL D +I A
Sbjct: 179 VAYD---YHDSIEELAANCDVLIIAA 201
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 84.2 bits (199), Expect = 3e-15
Identities = 56/172 (32%), Positives = 83/172 (48%)
Frame = +2
Query: 239 VPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVR 418
+P +LL V + + + D + E+++A GP L+V+A VG D+ID+ + RG+
Sbjct: 38 MPADDLLARVPEADALIVGM-DLVTAEVIEA-GPRLRVIAKHGVGVDNIDLDAARARGIP 95
Query: 419 IGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIV 598
+ + P +RR+ A H A G W + GP LAG T+G++
Sbjct: 96 VVFAPGSNSRAVAELTFGLMIAAARRIAAA-HTAVVAG--DWPKLY--GPELAGRTLGVI 150
Query: 599 GFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GFGRIG+ +A +AF + Y E E G VSF E L SDFV
Sbjct: 151 GFGRIGRLLAGYAQAFGMTVVGYDPFLDDGELTERGVRPVSFSECLAMSDFV 202
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 84.2 bits (199), Expect = 3e-15
Identities = 53/194 (27%), Positives = 90/194 (46%)
Frame = +2
Query: 173 PESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKV 352
PE+ L + C+V P+ EL++ + G++ + + D + +++ A P+LK+
Sbjct: 15 PEARAVLEQAGCEVIFNPYDRPLTEDELVELIKGMDALVAGM-DAVTAKVIAAGLPTLKI 73
Query: 353 VATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGG 532
+A VG++ IDVA G+ + TP +R +P+ + GG
Sbjct: 74 IAKHGVGYNTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGG 133
Query: 533 WVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAV 712
W + MTG L G +GI+G G IG VA+R AF + I Y R + + G
Sbjct: 134 W-----SRMTGSELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAYDIRPRQDMIENYGVT 188
Query: 713 KVSFDELLTQSDFV 754
+ + L Q+DF+
Sbjct: 189 YLPMADCLAQADFL 202
>UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase
YNL274C; n=13; Saccharomycetales|Rep: Putative
2-hydroxyacid dehydrogenase YNL274C - Saccharomyces
cerevisiae (Baker's yeast)
Length = 350
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/154 (33%), Positives = 66/154 (42%), Gaps = 2/154 (1%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T + D EL A S+ V G+D IDV KKR +++ PD+
Sbjct: 68 TGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLL 127
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGL--AGATVGIVGFGRIGQAVARRVKAFNT 652
R G W P + G G TVGI+G GRIG+ + R+K F
Sbjct: 128 LGALRNFGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGF 187
Query: 653 ERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
E IY NR P E+E G V F+E L +SD V
Sbjct: 188 ENFIYHNRHQLPSEEEHGCEYVGFEEFLKRSDIV 221
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 83.8 bits (198), Expect = 4e-15
Identities = 46/193 (23%), Positives = 95/193 (49%)
Frame = +2
Query: 176 ESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVV 355
E G+++LK + V + + + + + +L++++ N + ++ E++ AAG +LK++
Sbjct: 11 EEGIKILKSEPGVQV-DIETRLTKEQLIEKIKDYNALIIRSETQVTKEVI-AAGKNLKII 68
Query: 356 ATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW 535
VG D++DV ++G+ + P+ SR +P+A K+G
Sbjct: 69 GRAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSG-- 126
Query: 536 VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK 715
W + G + T+GI+G GRIG + +R ++F E + Y + ++ GA
Sbjct: 127 -KWERSKFMGVEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARL 185
Query: 716 VSFDELLTQSDFV 754
+ DE+ ++DF+
Sbjct: 186 TTLDEIYEKADFI 198
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 82.6 bits (195), Expect = 1e-14
Identities = 63/204 (30%), Positives = 92/204 (45%), Gaps = 1/204 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + + E+G+ LL+D+ +V++ V ELL+ + + + K+ E+L
Sbjct: 2 KILVTEA-ISETGISLLRDEHEVDV----RKVTSEELLEIIPEYDALITRSETKVTAEVL 56
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
A G LKVV VG D+IDVA +RGV + P +R +P+
Sbjct: 57 -ARGTRLKVVGRAGVGVDNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQ 115
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A H G W G L G T+GI+G GRIG VA R +AF + Y
Sbjct: 116 AHHALAREG--RWDRMSFVGTELHGKTLGIIGLGRIGSEVAVRARAFGMRVLAYDPYVPH 173
Query: 686 PEEKETGAVKV-SFDELLTQSDFV 754
+ G V S LL + DF+
Sbjct: 174 SRAEHLGVTLVPSLRGLLPEVDFL 197
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 82.2 bits (194), Expect = 1e-14
Identities = 54/181 (29%), Positives = 79/181 (43%)
Frame = +2
Query: 212 VNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDV 391
+ L P + ++ + E G + + D L A P LK++A VG D+IDV
Sbjct: 26 IELVRVPPDISQSAFVLEARGAQAAIVAFNEIHDAVL--AQLPDLKIIAKHGVGVDNIDV 83
Query: 392 AECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPG 571
KK GV + P+ +R++P + K G W S + G
Sbjct: 84 DAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWPS-----LFGAD 138
Query: 572 LAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDF 751
+ T+GI+G G IG+ VARR F+ + Y R ++ G VS D LL QSDF
Sbjct: 139 VYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPYIDRTYARKNGIEAVSLDALLQQSDF 198
Query: 752 V 754
V
Sbjct: 199 V 199
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 82.2 bits (194), Expect = 1e-14
Identities = 56/204 (27%), Positives = 95/204 (46%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
+ I VT + E G++ L D + +QP P +L + +G+ K+ ++
Sbjct: 2 FNILVT-DKVSEEGLKKLYAHKDFIVEHQPGIAPE-DLKATIGQYDGLIVRNQTKVTKDI 59
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
++A+G +L+V+A VG D+IDV ++G+ + +P SR +P
Sbjct: 60 IEASG-NLRVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIP 118
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
+A H++ G W G L T+GI+G G+IG VA+R KAF + Y
Sbjct: 119 QA-HKSAAAG--KWEREKFKGVELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLT 175
Query: 683 RPEEKETGAVKVSFDELLTQSDFV 754
+ G K + DE+ Q+DF+
Sbjct: 176 EERAAKLGIKKATLDEIAAQADFI 199
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 82.2 bits (194), Expect = 1e-14
Identities = 52/193 (26%), Positives = 90/193 (46%)
Frame = +2
Query: 176 ESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVV 355
ES +++LK+ +V + + + E+ +++ + + + E++DA+ +LKV+
Sbjct: 12 ESAIEILKEAGEVEI---ATGISIEEIKQKIKDADALVVRSGTTVTKEIIDAS-ENLKVI 67
Query: 356 ATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW 535
A VG D++D+ ++GV + PD +R +P+A K G
Sbjct: 68 ARAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKG-- 125
Query: 536 VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK 715
W G + T+GIVG GRIGQ VA+R +AF + Y E G
Sbjct: 126 -EWDRKSFKGMEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPYIPENVASELGIKL 184
Query: 716 VSFDELLTQSDFV 754
+S DEL +S+F+
Sbjct: 185 LSVDELCAESEFI 197
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 82.2 bits (194), Expect = 1e-14
Identities = 58/203 (28%), Positives = 91/203 (44%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + E+GV LL++ DV+ SP +L K+VA + + K+ E+
Sbjct: 84 RILVTEK-LGEAGVNLLREFGDVDCSYDLSP---EDLKKKVAESDALIVRSGTKVTREVF 139
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+AA LKVV VG D++D+ + G + P +R V +
Sbjct: 140 EAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQ 199
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A K G W + G L G T+ ++GFG++G VARR K I + +
Sbjct: 200 ADASIKAG---KWERSKYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPA 256
Query: 686 PEEKETGAVKVSFDELLTQSDFV 754
+ G VSFD+ ++ +DFV
Sbjct: 257 DRARALGVDLVSFDQAISTADFV 279
>UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 387
Score = 81.8 bits (193), Expect = 2e-14
Identities = 50/152 (32%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T +ID ELL A P+L+ + G+D IDVA C GVR+ TP
Sbjct: 88 TGRIDAELLAALPPTLRFICHNGAGYDQIDVAACTAAGVRVSNTPSAVDDATADAGIFLM 147
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
R + + G W+ P G G +GI+G G IG+ +A++ F +
Sbjct: 148 LGALRNFGPGMQSCRNGEWIG-KPAPALGHDPRGKVLGILGMGGIGRNMAKKAAVFGM-K 205
Query: 659 IIYFNRSHRPEEKET--GAVKVSFDELLTQSD 748
I Y+NR+ E E GA V FD LL SD
Sbjct: 206 IRYYNRTRLSAELEADCGAEYVDFDTLLVTSD 237
>UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Congregibacter
litoralis KT71|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Congregibacter litoralis
KT71
Length = 316
Score = 81.4 bits (192), Expect = 2e-14
Identities = 51/152 (33%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Frame = +2
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
D + EL+ + SL ++A + VG D++D+ K+RG+ + TP V
Sbjct: 52 DPVSRELIASFPDSLGLIANLGVGTDNVDLVAAKERGILVSNTP-VVTEDTADLTFALLL 110
Query: 482 XXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERI 661
RRV E + G W A + G + GA +GI+GFG IGQAVA+R + F+ +
Sbjct: 111 ATCRRVGECERALRGGDWAGGAA--LMGRRVHGAKLGIIGFGAIGQAVAQRARGFDMDVG 168
Query: 662 IYFNRSHRPEEKETGA-VKVSFDELLTQSDFV 754
+ R E TGA S D+LL +SD V
Sbjct: 169 YHGPRRKADAEASTGARWYESLDQLLEESDIV 200
>UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=8; Chordata|Rep: Chromosome 21
SCAF14577, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 324
Score = 81.0 bits (191), Expect = 3e-14
Identities = 54/150 (36%), Positives = 74/150 (49%), Gaps = 5/150 (3%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P+LKVVA+ G DH+DVA GV++ +TP V +R + H
Sbjct: 69 PALKVVASGGAGIDHLDVAYINSLGVKVTHTPGVVSSATADIALGLLLASARDIV-TYHR 127
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR---- 685
+ PT M G + G+T+GIVG G IG +A+R + F +I+Y NR R
Sbjct: 128 IAADPKTADLPTMM-GVDVTGSTMGIVGMGDIGYKIAQRGRGFEM-KILYHNRRRRKVSV 185
Query: 686 PEEKETGAVKV-SFDELLTQSDFVICCAXL 772
EE+ GA S DELL +SDFV+ L
Sbjct: 186 KEEQAVGATYCQSLDELLKESDFVVLAVNL 215
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 80.2 bits (189), Expect = 5e-14
Identities = 48/154 (31%), Positives = 73/154 (47%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++D L S+ +AT SVG DHID+ + RG+ + TP +
Sbjct: 56 RVDAAFLAGLPASVGALATYSVGLDHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLA 115
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+RR+ EA + G W + + G LAG T+GI G G IG+ VARR AF R++
Sbjct: 116 ATRRMAEATALLREGRWTDLWSSHILGVELAGRTLGIYGLGDIGRRVARRATAFGM-RLV 174
Query: 665 YFNRSHRPEEKETGAVKVSFDELLTQSDFVICCA 766
Y NR R ++ + +E L +D ++ A
Sbjct: 175 YHNR-RRAVDEAGATFAATAEEFLASADILLLAA 207
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 80.2 bits (189), Expect = 5e-14
Identities = 46/139 (33%), Positives = 70/139 (50%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L++VAT S G DHID+ C+KRG+ + + PD +R + +A
Sbjct: 70 PRLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHER 129
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
A+ G S+A +TG L G T+GIVG GRIG+ VAR F + + Y +
Sbjct: 130 ARQG---SFAYRGLTGFELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAASAAR 186
Query: 698 ETGAVKVSFDELLTQSDFV 754
G V+++++L SD +
Sbjct: 187 PAGVSLVTWEQVLQGSDIL 205
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 80.2 bits (189), Expect = 5e-14
Identities = 46/192 (23%), Positives = 86/192 (44%)
Frame = +2
Query: 179 SGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVA 358
SGV L+++ + + + +P EL + + + K+ ++L+A P LK VA
Sbjct: 14 SGVSRLENESGFAV-DVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAGAPKLKAVA 72
Query: 359 TISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWV 538
+G D++D+ K GV + TP+ +R +P+ ++G
Sbjct: 73 RAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSG--- 129
Query: 539 SWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV 718
W + G + T+G++GFG+IG VA R + I++ R + G V
Sbjct: 130 QWEKKKLQGREVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDPNIARTTIENEGFEYV 189
Query: 719 SFDELLTQSDFV 754
S D+L ++D++
Sbjct: 190 SLDDLFARADYI 201
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 80.2 bits (189), Expect = 5e-14
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +2
Query: 239 VPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVR 418
+ R ELLK + + K+D E++ G +LK++A +G D+ID E KR ++
Sbjct: 47 ITREELLKIIDQYQVLIVRSRTKVDKEII-RYGVNLKIIARAGIGLDNIDTEEASKRNIK 105
Query: 419 IGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIV 598
I Y P +R++ ++++ AK G + + G LAG T+GIV
Sbjct: 106 IVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFKK-----IEGIELAGKTIGIV 160
Query: 599 GFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGA-VKVSFDELLTQSDFV 754
GFGRIG VA+ KA + I Y + + + G V S +ELL SD +
Sbjct: 161 GFGRIGTKVAKVCKALDMNVIAYDVINIKEKANIVGVRVAESLEELLKNSDVI 213
>UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15;
Pseudomonadales|Rep: 2-keto-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 321
Score = 79.8 bits (188), Expect = 7e-14
Identities = 55/198 (27%), Positives = 92/198 (46%), Gaps = 2/198 (1%)
Frame = +2
Query: 185 VQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATI 364
++ LK Q V + + ++ +EV +G+ + ++ E A LK+V+T+
Sbjct: 16 LEQLKQQYQVVVLDPKKGDINEQICQEVVDADGMIGA--GRLLNENNLAPAQHLKIVSTV 73
Query: 365 SVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSW 544
SVG+D+ DV ++ + + +TP V +R+VP+ K G W
Sbjct: 74 SVGYDNYDVQYLNQKKIWLAHTPHVLTETTADLAFTLLVSAARKVPQLDAWTKAGEWKRT 133
Query: 545 APTWMTGPGLAGATVGIVGFGRIGQAVARR-VKAFNTERIIYFNRSHR-PEEKETGAVKV 718
G + G T+GI+G G IG A+ARR + FN I+Y NR + + A
Sbjct: 134 VGAAQFGQDIFGKTLGIIGLGNIGAAIARRGLYGFNM-NILYHNRHEKLVLAQPLNAEYC 192
Query: 719 SFDELLTQSDFVICCAXL 772
S +LL +SDF++ L
Sbjct: 193 SMQDLLQRSDFIVVAVDL 210
>UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1;
Bordetella avium 197N|Rep: Putative reductase precursor
- Bordetella avium (strain 197N)
Length = 315
Score = 79.8 bits (188), Expect = 7e-14
Identities = 59/194 (30%), Positives = 91/194 (46%), Gaps = 1/194 (0%)
Frame = +2
Query: 179 SGVQLLKDQCDV-NLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVV 355
S Q L + DV LW P EL + GV + S + EL++A P LK +
Sbjct: 18 SANQRLAEAYDVIELWKHADR-PLTELGR---GVTALVTSASTGASAELINAL-PDLKAI 72
Query: 356 ATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW 535
+ VG++ I+V +RGV++ TPDV +RR+ + + G W
Sbjct: 73 CSWGVGYETINVEAAHRRGVQVSNTPDVLTDCVADLAWGLLISAARRMGQGERFVRAGQW 132
Query: 536 VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK 715
+ G ++G +G++G GRIG+A+ARR F+ E + Y NR R + A
Sbjct: 133 GQVHGSLPLGMRVSGKKLGVIGLGRIGEAIARRGAGFDME-VRYHNRRQRTDVSYGYAAN 191
Query: 716 VSFDELLTQSDFVI 757
+S EL +DF+I
Sbjct: 192 LS--ELAEWADFLI 203
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 79.4 bits (187), Expect = 9e-14
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 1/185 (0%)
Frame = +2
Query: 203 QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDH 382
Q DV + + P+ A +L E+AG + D I ++D + P LKV++ +G D
Sbjct: 24 QLDVEVVRERGPLSEARML-ELAGQFDAFLCGDDAITAAVIDKSLPRLKVISKYGIGLDK 82
Query: 383 IDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMT 562
IDVA + + + +TP V + + ++GGW T
Sbjct: 83 IDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKR-----KT 137
Query: 563 GPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSF-DELLT 739
G L T+GIVG GRIG+ VA R +AF E I Y K+ +V+ +E+ T
Sbjct: 138 GHELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYDIYWDEAFAKQHNVKRVATKEEIFT 197
Query: 740 QSDFV 754
+D++
Sbjct: 198 SADYI 202
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 79.4 bits (187), Expect = 9e-14
Identities = 52/151 (34%), Positives = 70/151 (46%), Gaps = 1/151 (0%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
KI EL+ A P LK++ VG D+ID+A K G+ + TP
Sbjct: 55 KITQELIQKA-PKLKMIQKTGVGVDNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIIN 113
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
R++ E K G W+SW + + G T GI+GFG IG+ VAR +AF T I
Sbjct: 114 LYRKINILDRETKKGNWMSWEFR-PSSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIY 172
Query: 665 YFNRSHRP-EEKETGAVKVSFDELLTQSDFV 754
Y R P EEK +ELL +SD +
Sbjct: 173 YDLRRLEPAEEKRLNVTYHELNELLQKSDII 203
>UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia
aggregata IAM 12614|Rep: Glycerate dehydrogenase -
Stappia aggregata IAM 12614
Length = 319
Score = 79.4 bits (187), Expect = 9e-14
Identities = 51/181 (28%), Positives = 89/181 (49%), Gaps = 6/181 (3%)
Frame = +2
Query: 170 MPESGVQLLKDQCDV-----NLWNQPSPVPR-AELLKEVAGVNGIYCSLTDKIDTELLDA 331
MP + ++++Q D L+ +P AE+ K++ GV + ++ E L A
Sbjct: 8 MPRPMLPIVQEQLDAAFTVHRLYEADNPEALLAEIGKKIRGVAMAF----GPVNAEFL-A 62
Query: 332 AGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAI 511
P+ ++V++ VG+DHI+ +C V + +TPDV R +A
Sbjct: 63 KVPNAEIVSSFGVGYDHINTDDCLAANVMVTHTPDVLTEEVADTALGLMIMTIREFGQAE 122
Query: 512 HEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE 691
+ G W S P +TG + G T+GI G GRIG+A+A+R +AF I+++ H+ +
Sbjct: 123 QWLRQGNWESKGPYKLTGATMQGRTLGIFGLGRIGKAIAKRAEAFG--MTIHYHGRHKQD 180
Query: 692 E 694
+
Sbjct: 181 D 181
>UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 327
Score = 79.0 bits (186), Expect = 1e-13
Identities = 51/206 (24%), Positives = 94/206 (45%)
Frame = +2
Query: 155 VTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAA 334
V + E ++ L+ + +V + P P ++L + + + + +TD + E L A
Sbjct: 7 VVTQPVHEEVLRKLQAEGEVIMNPGPDPWSPSQLREYLVDADAMMAFMTDSVTKESLLNA 66
Query: 335 GPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIH 514
P LK ++ G+D+ D+ C + GV + + PD+ R V +
Sbjct: 67 -PRLKTISCALKGYDNFDLRACAQAGVSVTFVPDLLTEPTAELAIGLAIAAGRNVLQG-D 124
Query: 515 EAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEE 694
A G+ W P + G GL G+ ++G G++GQA+ R+ F R++ + S R ++
Sbjct: 125 AATRAGYSGWRPA-LYGTGLHGSVASVIGLGKVGQAILARLAGFGCARLLGVDPSVRLDQ 183
Query: 695 KETGAVKVSFDELLTQSDFVICCAXL 772
E V+ DE ++ SD+V L
Sbjct: 184 VEL----VTLDEAVSTSDYVFLAVPL 205
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 79.0 bits (186), Expect = 1e-13
Identities = 50/192 (26%), Positives = 83/192 (43%)
Frame = +2
Query: 179 SGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVA 358
+G+ LLKD +V+ SP EL +++ + + K+ E+ +A+ LKVV
Sbjct: 123 AGLDLLKDFANVDCAYNLSP---EELCTKISLCDALIVRSGTKVSREVFEASSGRLKVVG 179
Query: 359 TISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWV 538
VG D++D+A + G + P +R V +A K+G
Sbjct: 180 RAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSG--- 236
Query: 539 SWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV 718
W G L G T+ ++GFG++G V RR K I + + + G V
Sbjct: 237 KWQRNKYVGVSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAIGVELV 296
Query: 719 SFDELLTQSDFV 754
FDE ++ +DF+
Sbjct: 297 GFDEAISTADFI 308
>UniRef50_Q4P4C6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 381
Score = 79.0 bits (186), Expect = 1e-13
Identities = 55/189 (29%), Positives = 85/189 (44%), Gaps = 11/189 (5%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAEL----LKEVAGVNG-IYCSLTDKIDTELLDAA 334
+P ++ + + +NL + P + AEL L+++ G + I + + + ++AA
Sbjct: 27 LPSPILETFRREGRINLISAPPGLSFAELNEWLLRQLPGADAAIVWPVAGQFGVDQINAA 86
Query: 335 GPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIH 514
LKVV+T SVG + +D C+K G+ +GYTP + RR+
Sbjct: 87 SERLKVVSTYSVGTEAVDRVACRKAGITVGYTPYIGDDSIAEYTIAMLLHFCRRIDYLQS 146
Query: 515 EAKTGGW------VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
G + V PT G AG TVG GFGRI Q A ++ AF RI Y
Sbjct: 147 IVMNGQFAASLRDVLCNPTMHCGVSPAGKTVGFYGFGRIAQKAAEKLLAFGVARIAYTTS 206
Query: 677 SHRPEEKET 703
+ +P ET
Sbjct: 207 TAKPFSAET 215
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 79.0 bits (186), Expect = 1e-13
Identities = 52/172 (30%), Positives = 82/172 (47%)
Frame = +2
Query: 239 VPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVR 418
+ + +L+K + N + KID +++DA G +LK++A VG D++DV K+G+
Sbjct: 30 ISKDDLIKIIKNYNILIFRGRLKIDKDIMDA-GQNLKILARYGVGLDNVDVEYAVKKGIA 88
Query: 419 IGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIV 598
+ P+ +RR+P + K G W G +AG T+GIV
Sbjct: 89 VVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAG---EWPKGKYIGIEIAGKTMGIV 145
Query: 599 GFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GFGRIG+ VA+ K+ + E + G +V +ELL QSD V
Sbjct: 146 GFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKIGGRQVPLEELLRQSDVV 197
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 78.6 bits (185), Expect = 2e-13
Identities = 47/170 (27%), Positives = 79/170 (46%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
+ EL+ E+ +G+ K+ +++ AA P+LK+V G D+ID+ + G+ +
Sbjct: 37 KEELINELQKHDGLIVRSETKVTADVI-AASPNLKLVGRAGTGVDNIDIPAATRNGILVL 95
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP +R V +A K G W G L+G +G+VGF
Sbjct: 96 NTPGGNSVSACELTCAVISALARNVVQAGQSMKEG---RWDRKLYAGRELSGKALGVVGF 152
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GRIG+ VA R+KAF E I Y + + + G K +++ +D++
Sbjct: 153 GRIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNADYI 202
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 78.6 bits (185), Expect = 2e-13
Identities = 57/193 (29%), Positives = 85/193 (44%), Gaps = 1/193 (0%)
Frame = +2
Query: 179 SGVQLLKDQCDVNLWNQPSPVPRAELLKEVAG-VNGIYCSLTDKIDTELLDAAGPSLKVV 355
+ VQ+ KD+ V++ P E L EV G +G+ K+ TE L AA LKVV
Sbjct: 19 TAVQIFKDR-GVDVDYLPDLGKDKEKLLEVIGEYDGLAIRSATKV-TEKLIAAAKKLKVV 76
Query: 356 ATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW 535
+G D++D+ +RG+ + TP +R++PEA + G
Sbjct: 77 GRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAG-- 134
Query: 536 VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK 715
W G + G T+G+VG G IG VA R + + +E G K
Sbjct: 135 -KWEKNRFMGVEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEK 193
Query: 716 VSFDELLTQSDFV 754
V DELL ++DF+
Sbjct: 194 VELDELLARADFI 206
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 78.6 bits (185), Expect = 2e-13
Identities = 49/174 (28%), Positives = 74/174 (42%)
Frame = +2
Query: 233 SPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG 412
+P AE + + IY I ++DA S KV+ SVG D +DV RG
Sbjct: 78 APANEAEFIAAAKNADAIYAKGIP-ITKSIIDAL-ESCKVITLGSVGVDSVDVKAATARG 135
Query: 413 VRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVG 592
+ + PD RR+ E ++G W P + P L G T+G
Sbjct: 136 IPVTNIPDTFIEEVADHAMMLLLAGFRRLVEQDRMVRSGRWAEGRPALLKIPRLMGQTLG 195
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
+ FGR+ +AVA+R F + Y + G + + +E+L+QSDFV
Sbjct: 196 FISFGRVARAVAKRAAPFGLRMMAYDPFIQETLMYDHGVIPATLNEVLSQSDFV 249
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 78.2 bits (184), Expect = 2e-13
Identities = 55/170 (32%), Positives = 73/170 (42%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
R ELL + + I K+D E L AA LKV+A VG D++DV + GV +
Sbjct: 42 RGELLAALPEADAILVRSATKVDAEAL-AAARRLKVIARAGVGLDNVDVRAATQAGVMVV 100
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
P +R + A H A G W TG L TVGIVG
Sbjct: 101 NAPTSNIVSAAELAVALMLAAARHISPA-HAALKNG--EWKRARYTGTELYEKTVGIVGL 157
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GRIG VA+R+ AF + + Y + G V D LL ++DF+
Sbjct: 158 GRIGVLVAQRLSAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTLLAEADFM 207
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 78.2 bits (184), Expect = 2e-13
Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 4/183 (2%)
Frame = +2
Query: 137 GRYQIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAG--VNGIYCSLTDK 307
G+Y++ T+ + LL +Q C V + + + E + + G +G+ LT+
Sbjct: 14 GKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIGDKCDGVIGQLTED 73
Query: 308 IDTELLDAAGPSL-KVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
L A + K + ++VG++++DV K GV +G TP V
Sbjct: 74 WGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLA 133
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+RR+ EA + G + W P G L G TVG++G GRIG A AR + +I
Sbjct: 134 AARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
Query: 665 YFN 673
YF+
Sbjct: 194 YFD 196
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 77.8 bits (183), Expect = 3e-13
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTEL 322
Y++ +T PE G++LL+ +V ++N+P + ELL+ + + I + EL
Sbjct: 2 YKVLITDPIAPE-GIELLQKDPEVEVYNEPD-ISYEELLEIIKDFDAIITRSRTPVTKEL 59
Query: 323 LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVP 502
L+ A LKVV VG D++D+ E KRG+ + TP R
Sbjct: 60 LERA-EKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGH 118
Query: 503 EAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
+A HE+ W G L G +GI+G G IG VA R KAF + + Y
Sbjct: 119 KA-HESMLN--YKWDRKKFMGEELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPYIP 175
Query: 683 RPEEKETGAVKV-SFDELLTQSDFVICCAXL 772
R + ++ G V + ++L + D + A L
Sbjct: 176 REKAEKLGVKLVDNLHDMLREIDVLTIHAPL 206
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 77.4 bits (182), Expect = 4e-13
Identities = 53/204 (25%), Positives = 91/204 (44%), Gaps = 1/204 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++ VT + E GV+LL+ + +V++ SP ELL+ + +G+ K+ E++
Sbjct: 2 RVLVTEK-LAERGVELLRREFEVDVLLGLSP---GELLERIGEYDGLIVRSATKVTAEVI 57
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+AAG LK + +G D+ID+ KRG+ + P+ +RR+P
Sbjct: 58 EAAG-RLKAIGRAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPA 116
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A + G W A G +A T+G+VG G +G VAR + Y
Sbjct: 117 ADASLRRGEWNRAA---FKGVEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPYVSE 173
Query: 686 PEEKETGAVKV-SFDELLTQSDFV 754
+ + S +E+ ++DFV
Sbjct: 174 ERMRSMNVERAGSLEEIFEEADFV 197
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 77.4 bits (182), Expect = 4e-13
Identities = 49/151 (32%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++ EL++ A +LKV+A VG D+IDV +RG+ + P+
Sbjct: 52 RVTRELIEEA-KNLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILA 110
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+R++P+A + G W G LAG T+G++G GRIGQ VA+R KAF E
Sbjct: 111 LARKIPQADRSVRRG---EWDRKRFMGVELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTA 167
Query: 665 YFNRSHRPEEKETGAVKV-SFDELLTQSDFV 754
Y +E G V +ELL ++D V
Sbjct: 168 YDPYIPEKVAEELGVELVDELEELLERADVV 198
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 77.0 bits (181), Expect = 5e-13
Identities = 57/192 (29%), Positives = 89/192 (46%), Gaps = 1/192 (0%)
Frame = +2
Query: 182 GVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVAT 361
G++LL+ + + + + + R +LL + +G+ ID EL++ A LKVV
Sbjct: 16 GIELLESEPNFEV-DIKMGLEREKLLNIIENYDGLIIRSDTNIDIELMNMA-KKLKVVGR 73
Query: 362 ISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS 541
G D+ID+ E KRG+ + TPD SR + + K G W
Sbjct: 74 AGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWD- 132
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV- 718
++M G L T+GI+G GRIG VA R+ AF+ + I Y K K
Sbjct: 133 -RDSFM-GTELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDERFKRFNVEKKD 190
Query: 719 SFDELLTQSDFV 754
+ ++LL +SDF+
Sbjct: 191 TLEDLLKESDFI 202
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 77.0 bits (181), Expect = 5e-13
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 2/170 (1%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
EL+K + +G+ K+ E+L+AA +LKVV +G D++DV K+GV +
Sbjct: 34 ELVKIIPAYDGLVIRSASKVTAEILEAA-ENLKVVGRAGIGLDNVDVPAASKKGVVVMNA 92
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
PD +R +P+A K G W G + G+VG GR
Sbjct: 93 PDGNATTAAEHAVSMMMALTRNIPQATASMKAG---KWEKKKFQGHEVTAKVAGVVGIGR 149
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPEE--KETGAVKVSFDELLTQSDFV 754
IG+ A R ++I F+ H P E ++ G V+ +EL ++D++
Sbjct: 150 IGRIFAERAMGLRM-KVIAFD-PHMPAEQMEKIGVEPVTLEELCQRADYI 197
>UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep:
AFR675Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 353
Score = 76.6 bits (180), Expect = 6e-13
Identities = 51/154 (33%), Positives = 68/154 (44%), Gaps = 2/154 (1%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T D EL + S+ V G+D ID KR +++ P +
Sbjct: 67 TGLFDRELAEHLPASVVAVCQNGAGYDQIDPESFTKRQIQVANVPGLVNAPTADTHVFLL 126
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMT--GPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
R + G W AP T G AG TVG++G G IG+AV +R++ F
Sbjct: 127 LAALRNFCHGQLLLRQGRWPD-APVAGTPFGHDPAGKTVGVLGMGGIGRAVVQRLRPFGF 185
Query: 653 ERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
ERIIY NR+ E E VSF+ELL QSD +
Sbjct: 186 ERIIYHNRNRLSSELECSCEYVSFEELLAQSDIL 219
>UniRef50_UPI0000586D88 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 390
Score = 76.2 bits (179), Expect = 9e-13
Identities = 55/163 (33%), Positives = 85/163 (52%), Gaps = 10/163 (6%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+D ELL + +LKV+AT S G +H+D+ K G+++G+ +
Sbjct: 67 MDEELLRSMS-NLKVLATHSTGTNHLDLPLLWKLGIKVGHARGILDDTCADFVFGLLIAA 125
Query: 488 SRRVPEAI-----HEAKTGGW-VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFN 649
+RR+PE I HE GW S P G ++GA +GI+G G IG VARR F
Sbjct: 126 ARRLPECIAHAQGHEGTEPGWDKSNVP---IGVAVSGARLGILGMGSIGYEVARRATGFK 182
Query: 650 TERIIYFNRSHR--PEEKETGAVK-VSFDELLTQSDF-VICCA 766
+++Y NR+ R EE+E A +S +++L + D+ VI C+
Sbjct: 183 M-KVLYHNRTQRSAAEEREVNATYCLSLEKMLPELDYLVITCS 224
>UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0111:
Phosphoglycerate dehydrogenase and related
dehydrogenases - Magnetospirillum magnetotacticum MS-1
Length = 311
Score = 76.2 bits (179), Expect = 9e-13
Identities = 57/174 (32%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = +2
Query: 248 AELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGY 427
A+LL +A +GI C D+I ++DAA +LKV++ G D ID A +G+ G
Sbjct: 42 ADLLPIIAKYHGIVCG-DDRITKTVIDAAA-NLKVISKWGTGIDSIDSAYAATKGIPTGR 99
Query: 428 TPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFG 607
T D +R +P K G W + G L +T+G+VG G
Sbjct: 100 TLDAFTQPVADTALGYILSFARNLPWMDKMMKAGIWDK-----IPGRALNESTIGVVGVG 154
Query: 608 RIGQAVARRVKAFNTERIIYFNRSHRPE-EKETGAVKVSFDELLTQSDFV-ICC 763
+G AV RR K F + R+ P E G + D LL QSDFV +CC
Sbjct: 155 CMGSAVLRRAKPFGARLLGNDIRTIDPAFVAEVGVEMMDLDSLLEQSDFVSVCC 208
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 76.2 bits (179), Expect = 9e-13
Identities = 57/204 (27%), Positives = 96/204 (47%), Gaps = 1/204 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
QI + D+ ESG L+++ Q S + + + +G+ T E+
Sbjct: 3 QIILIPQDVDESGKNYLQEKGYELRILQDSSIEN--ICNNIGDCSGLLLR-TVPCTKEVF 59
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
DAA P LKV+ VG+D+ID+AE +G+++ YTP ++ +
Sbjct: 60 DAA-PHLKVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVI 118
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A E + G + M G + G T+GI+GFGRIG++VA++ +I+ + R
Sbjct: 119 ADKELRQGNYE--IRNQMPGIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAYGRGLE 176
Query: 686 PEE-KETGAVKVSFDELLTQSDFV 754
+E + + DEL+ QSDF+
Sbjct: 177 IKEVPDYVTIIKEVDELIRQSDFI 200
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 75.8 bits (178), Expect = 1e-12
Identities = 48/151 (31%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
+D ELLDA G LK+V+ VG+DHIDV +G+ + P
Sbjct: 60 VDQELLDA-GKKLKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAEMAFTLLLAL 118
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
SR++ E + ++ G G T+GI G GRIG+ +A + F I+Y
Sbjct: 119 SRKLALYNQEMRQENFLDTGLLENQGQSPVGKTLGIFGMGRIGKTLASYARTFGM-NILY 177
Query: 668 FNRSHRPEEKE--TGAVKVSFDELLTQSDFV 754
NR PE++E G V +LL+Q+D+V
Sbjct: 178 HNRHQLPEDEERALGVSYVPLADLLSQADYV 208
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 75.8 bits (178), Expect = 1e-12
Identities = 59/195 (30%), Positives = 91/195 (46%), Gaps = 2/195 (1%)
Frame = +2
Query: 176 ESGVQLL-KDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKV 352
E GV++ K V++ + SP EL +E++ +G+ K+ E+L A LKV
Sbjct: 15 EDGVRIFQKAGFHVDMKTKLSP---QELAQEISQYDGLVIRSGTKVTREILKNAD-RLKV 70
Query: 353 VATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGG 532
+ G D++D+ +RG+ + TP +RR+P+A K G
Sbjct: 71 IGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAG- 129
Query: 533 WVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKE-TGA 709
W + G L T+GIVG G+IGQ VA+ + II F+ PE E +G
Sbjct: 130 --KWEKSKFMGVELFQKTLGIVGMGKIGQHVAQIARGI-AMNIIAFDPYLTPEVAEKSGV 186
Query: 710 VKVSFDELLTQSDFV 754
VS DEL ++DF+
Sbjct: 187 HPVSLDELFQRADFI 201
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 5/182 (2%)
Frame = +2
Query: 137 GRYQIYVTRSDMPESGVQLLKDQ-CDVNLWNQPSPVPRAELLKEVAG--VNGIYCSLTDK 307
G+Y++ T+ + LL Q C V + Q + E + + G +G+ LT+
Sbjct: 14 GKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIGDKCDGVIGQLTED 73
Query: 308 IDTELLDAAGPSL-KVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
L A + + + ++VG++++DV K GV +G TP V
Sbjct: 74 WGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMA 133
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVAR-RVKAFNTERI 661
+RR+ EA + G + W P G L G TVG++G GRIG A AR V+ F I
Sbjct: 134 AARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
Query: 662 IY 667
Y
Sbjct: 194 YY 195
>UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Porphyromonadaceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Porphyromonas gingivalis
(Bacteroides gingivalis)
Length = 319
Score = 74.9 bits (176), Expect = 2e-12
Identities = 52/159 (32%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
Frame = +2
Query: 284 IYCSLTD-KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXX 460
+ CS+ D I +L+D G SLK++A +VG+++IDV +G+ + TP
Sbjct: 47 VLCSVFDIPIGRDLIDK-GRSLKLIANYAVGYNNIDVTYAASKGIVVTNTPRAVIEPTAD 105
Query: 461 XXXXXXXXXSRRVPEAIHEAKTGG-WVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRV 637
+RR+ E + G V G L G T+GI+GFG IG AVARR
Sbjct: 106 LALALLLSCTRRIAEWDRLFRRDGEMVERGRLCRLGVNLYGKTLGIIGFGNIGAAVARRC 165
Query: 638 KAFNTERIIYFNRSH--RPEEKETGAVKVSFDELLTQSD 748
KAF ++Y R+ EEK G D+L+ ++D
Sbjct: 166 KAFGM-NVLYNKRTRLSEAEEKAQGITFADKDDLIRRAD 203
>UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n=1;
Gluconobacter oxydans|Rep: Putative 2-hydroxyacid
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 310
Score = 74.9 bits (176), Expect = 2e-12
Identities = 49/153 (32%), Positives = 71/153 (46%), Gaps = 1/153 (0%)
Frame = +2
Query: 236 PVPRAELLKEVA-GVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG 412
P E LK +A + GI + +E++DA P+L+V++ VG D I++ E ++R
Sbjct: 29 PYTSLENLKNIAPAIRGITTGGGSGVPSEIMDAL-PNLEVISVNGVGTDRINLDEARRRN 87
Query: 413 VRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVG 592
+ + T + R + + G W S T G L VG
Sbjct: 88 IGVAITQNTLTDDVADMAVALMMAVMRSIVTNDAFVRAGKWPS--ATAPLGRSLTRKKVG 145
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE 691
I GFG IGQA+A+RV AF E + YFN RPE
Sbjct: 146 IAGFGHIGQAIAKRVSAFGME-VAYFNSHARPE 177
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 74.9 bits (176), Expect = 2e-12
Identities = 55/204 (26%), Positives = 86/204 (42%), Gaps = 9/204 (4%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLK 349
+ E+G+ +L+ DV SP AELL +VA + + K+ E+L+A L+
Sbjct: 86 LSEAGLAVLRGFADVECAYGMSP---AELLAKVAQFDALIVRSGTKVTREVLEAGRGRLR 142
Query: 350 VVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKT- 526
VV VG D++D+ + G + P +R V +A K
Sbjct: 143 VVGRAGVGIDNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAV 202
Query: 527 --------GGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSH 682
W T G L G T+ ++GFG++G VARR K I + +
Sbjct: 203 YSRTLTVFTAQGKWQRTKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAP 262
Query: 683 RPEEKETGAVKVSFDELLTQSDFV 754
+ GA VSFDE + ++DF+
Sbjct: 263 ADRARAIGAELVSFDEAIGRADFI 286
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 74.5 bits (175), Expect = 3e-12
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 2/206 (0%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKE-VAGVNGIYCSLTDKIDTE 319
Y+ VT P +G++LL+++ + + + P E+LKE + G + + K+ E
Sbjct: 2 YRALVTDKVHP-AGLELLREKGIEVVEDLEAYKP--EVLKERIKGFDVLIVRSRTKVRRE 58
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+++AA LKV+A G D+ID+ K++G+++ PD +RR
Sbjct: 59 VIEAAD-KLKVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRA 117
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
+ + G W + G LAG T+G+VGFGRIG+ VA++ KA I Y
Sbjct: 118 HYSYRKLLEGEWEK-----VMGFELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYDVVD 172
Query: 680 HRPEEKETGA-VKVSFDELLTQSDFV 754
KE G +ELL +SD V
Sbjct: 173 LSETAKEMGVEFTQDLEELLRKSDVV 198
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 74.5 bits (175), Expect = 3e-12
Identities = 48/188 (25%), Positives = 84/188 (44%)
Frame = +2
Query: 209 DVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHID 388
+V + + + + + +L + V V I ++ +ID E++DAA P+LK + G+D+ID
Sbjct: 27 NVTILDTDNGIEKEKLKQAVREVEVIITAVV-QIDKEIIDAA-PNLKYIMKFGAGYDNID 84
Query: 389 VAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGP 568
+++G+ + TP +R +P E + G W G
Sbjct: 85 FKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNW-----ELSMGI 139
Query: 569 GLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSD 748
+ +GI+GFG IGQA+A+R F E + Y + V ++LL +SD
Sbjct: 140 EIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTFQDQTIADRLNVEFVDLNKLLNESD 199
Query: 749 FVICCAXL 772
V+ L
Sbjct: 200 IVVVSTTL 207
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 74.5 bits (175), Expect = 3e-12
Identities = 53/169 (31%), Positives = 82/169 (48%), Gaps = 1/169 (0%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
++L+ V V+ I KI E++ AA P LKVV VG D++DV +RGV + T
Sbjct: 35 KVLELVKDVHAIAVRSETKITREVI-AAAPQLKVVGRAGVGVDNVDVEAATERGVVVMNT 93
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
P SR V +A + G W + +G L T+G++G GR
Sbjct: 94 PAGNTIATAELTFTHILCGSRPVSQAAASMREGKWDRKS---FSGVELFKKTLGVIGMGR 150
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV-SFDELLTQSDFV 754
IG VARR AF +++ ++ P + V+V + DE+L Q+D++
Sbjct: 151 IGGEVARRAVAFGM-KVLAYDPYLAPSRAKAMQVEVATLDEILAQADYI 198
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 74.5 bits (175), Expect = 3e-12
Identities = 47/150 (31%), Positives = 65/150 (43%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T D ELL SLK + G+D+ID+ C ++G+ + TP
Sbjct: 62 TGPFDAELLSVLPKSLKYICHNGAGYDNIDIPACSEKGIAVSSTPVAVNHATADVGIFLM 121
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
R+ + + G W G G +GI+G G IG+ +A R +AF +
Sbjct: 122 IGALRQAYIPLSALRAG---QWQGKTTLGHDPQGKVLGILGMGGIGREMANRARAFGM-K 177
Query: 659 IIYFNRSHRPEEKETGAVKVSFDELLTQSD 748
I Y NRS E E A VSFDELL +D
Sbjct: 178 IQYHNRSRLSPELEGDAQYVSFDELLANAD 207
>UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: 2-hydroxyacid
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 335
Score = 74.5 bits (175), Expect = 3e-12
Identities = 46/148 (31%), Positives = 68/148 (45%)
Frame = +2
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D EL++ S+K + G+D IDVA C RG+++ +TP
Sbjct: 74 DEELINKLPASVKYICHNGAGYDQIDVAACTARGIQVSHTPQAVDDATATVGAFLAISAM 133
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYF 670
R+ A ++G W + P G T+GI+G G IG A+ARR+ AF+ + I Y
Sbjct: 134 RQFWRAEVNVRSGKWKAGLSP-ARDP--EGKTLGIIGMGGIGSALARRLLAFDMKVIYYN 190
Query: 671 NRSHRPEEKETGAVKVSFDELLTQSDFV 754
R +P S +ELL Q+D V
Sbjct: 191 RRPIQPPPNFPCTYVSSIEELLKQADVV 218
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 74.5 bits (175), Expect = 3e-12
Identities = 43/167 (25%), Positives = 76/167 (45%)
Frame = +2
Query: 254 LLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTP 433
LL + VN + ++ + +AA L +V +G D+ID+ + GV + P
Sbjct: 39 LLNTITDVNALVVRSGTDVNEAVFEAAS-DLIIVGRAGIGVDNIDIDAATEHGVIVANAP 97
Query: 434 DVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRI 613
+ +R +P+A +TG WA + G + G T+G+VG GR+
Sbjct: 98 EGNVRAAAEHTVAMTFAGARSIPQAHARLRTG---EWAKSEYLGTEVNGKTLGVVGLGRV 154
Query: 614 GQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GQ VA+R+++ + + Y + GA V FD L +++F+
Sbjct: 155 GQEVAKRLESLGMDLVAYDPYISEDRAERLGAELVEFDTCLERAEFL 201
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 74.5 bits (175), Expect = 3e-12
Identities = 54/205 (26%), Positives = 98/205 (47%), Gaps = 2/205 (0%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + E +++L++ +V + + + + ELL+++ + + K+ +++
Sbjct: 3 KILVT-DPLHEDAIKILEEVGEVEV---ATGLTKEELLEKIKDADVLVVRSGTKVTRDVI 58
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
+ A LKV+ VG D+IDV ++G+ + PD +R +P+
Sbjct: 59 EKA-EKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQ 117
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A K G W G L G T+G++G GRIGQ V +R KAF II ++
Sbjct: 118 ATASLKRG---EWDRKRFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGM-NIIGYDPYIP 173
Query: 686 PEEKETGAVKV--SFDELLTQSDFV 754
E E+ V++ +EL ++DF+
Sbjct: 174 KEVAESMGVELVDDINELCKRADFI 198
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 74.1 bits (174), Expect = 3e-12
Identities = 54/171 (31%), Positives = 77/171 (45%), Gaps = 3/171 (1%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
R E L+ + + + K+D ELLDAAGP LKV+ VG D+ID+ +RG+ +
Sbjct: 48 REETLRRLPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVDNIDLEYASRRGLLVL 107
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
P+ +R + + + + G W G L T+GIVG
Sbjct: 108 NAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEW----DRKFLGLELTDKTLGIVGL 163
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEK-ETGAVK--VSFDELLTQSD 748
GRIG VA R + + + Y + PE K E V+ S DELL Q D
Sbjct: 164 GRIGSIVADRAQGLHMNVVAY--DPYVPENKFERLGVQRAASLDELLGQVD 212
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 74.1 bits (174), Expect = 3e-12
Identities = 52/170 (30%), Positives = 82/170 (48%), Gaps = 2/170 (1%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAA--GPSLKVVATISVGHDHIDVAECKKRGVRIG 424
+L +++ V+ I KI EL+D A G LK++ VG D+IDV ++ G+++
Sbjct: 34 DLKEKIKKVDCIVIRSATKIRRELIDEAIKGGKLKLIIRGGVGVDNIDVQYAEQNGIKVR 93
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP+ +R + ++ K G W G L G T+GI+G
Sbjct: 94 NTPNASSSSVAEIILAHMFSLARFLNQSNITMKAG---LWKKKDYVGVELEGKTLGIIGM 150
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GRIG +A++ A +IIYF+ + + KV FDELL +SDF+
Sbjct: 151 GRIGSELAKKCTALGM-KIIYFDLMD-IKNIDNNYRKVEFDELLRESDFI 198
>UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Caulobacter sp. K31|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caulobacter
sp. K31
Length = 310
Score = 74.1 bits (174), Expect = 3e-12
Identities = 43/142 (30%), Positives = 66/142 (46%)
Frame = +2
Query: 260 KEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDV 439
+E+AG + ++ D +A P+L ++ I GHD +D E +RGV I + D
Sbjct: 30 EEIAGARAVVIRGSESFDAARFEAM-PALSLICCIGSGHDGVDAVEAARRGVTIATSGDA 88
Query: 440 XXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQ 619
R+V + + G W S A ++ PGL G GIVG G IG+
Sbjct: 89 NAAAVADHALALLLASVRQVVSSQALLRAGDWRSQATRIVSRPGLTGRRAGIVGLGAIGR 148
Query: 620 AVARRVKAFNTERIIYFNRSHR 685
+A R+ +F+ E I Y R+ R
Sbjct: 149 RIAARLSSFDCE-IGYTGRTLR 169
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 74.1 bits (174), Expect = 3e-12
Identities = 49/176 (27%), Positives = 76/176 (43%)
Frame = +2
Query: 227 QPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKK 406
Q + V EL K G+ ++K+ E++D P+LK V G++ ID+ +
Sbjct: 28 QEAGVDLVELAKAHPDTEGMIVR-SEKLTPEVIDLF-PNLKAVVRAGAGYNTIDIQYARS 85
Query: 407 RGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGAT 586
+ + + TP +R E + G W + G L G T
Sbjct: 86 KDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAG---EWKKAQLQGFELTGKT 142
Query: 587 VGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
VGI GFG IGQ +A+R+ F + ++Y + E GA VS +EL SDF+
Sbjct: 143 VGIAGFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGSDFI 198
>UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 353
Score = 74.1 bits (174), Expect = 3e-12
Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 2/156 (1%)
Frame = +2
Query: 293 SLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG--VRIGYTPDVXXXXXXXXX 466
S+T +D EL++ SL+ +A G+D IDV C R V + P
Sbjct: 79 SVTGLVDEELVNVLPNSLRYLAHCGAGYDQIDVDACSARSPPVLVSNVPTAVNDATADVN 138
Query: 467 XXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAF 646
R +I + G W P + G G +GI+G G IG+ + ++ +AF
Sbjct: 139 MFLIIGALRNFNTSILALREGKWKGQPPPKL-GHDPQGKVLGILGMGGIGRNLKKKAEAF 197
Query: 647 NTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
E IIY NR +E GA VSFDELL +SD +
Sbjct: 198 GLE-IIYHNRRKLSDELADGAEYVSFDELLGRSDVI 232
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 73.7 bits (173), Expect = 5e-12
Identities = 60/199 (30%), Positives = 87/199 (43%), Gaps = 4/199 (2%)
Frame = +2
Query: 170 MPESGVQLLKDQCDVNLWNQPSPVP-RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSL 346
M + VQ L DV +P V R LL +AG + + ++D LL+ A P+L
Sbjct: 11 MDPAAVQALTPGFDVRY--EPGWVDQRGALLDALAGADALIVRNRTQVDAALLERA-PAL 67
Query: 347 KVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKT 526
+VV + VG D+IDVA C+ RG+R+ R E
Sbjct: 68 RVVGRLGVGLDNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAG 127
Query: 527 GGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEE---K 697
G W G G T+G++GFG IG+ A +AF R++ + P++
Sbjct: 128 GKWP--RARLSEGREALGKTLGLIGFGDIGRQAAALAQAFGM-RVVAHDPMLAPDDPVWS 184
Query: 698 ETGAVKVSFDELLTQSDFV 754
TG V ++ D LL QSD V
Sbjct: 185 ATGVVCMTLDALLAQSDAV 203
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 73.7 bits (173), Expect = 5e-12
Identities = 51/195 (26%), Positives = 92/195 (47%), Gaps = 2/195 (1%)
Frame = +2
Query: 176 ESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVV 355
E+G +LL++ ++ + P+ + E+ + + +G++ K+D + + A LKV+
Sbjct: 27 ETGEKLLEEYTNIQILKDPT---KNEINQAIQEASGVFVRYPTKLDAQAIGLA-KKLKVI 82
Query: 356 ATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGW 535
+T G D ID++ K GV + P + ++++ KTG +
Sbjct: 83 STSGFGTDAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNY 142
Query: 536 VSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKET--GA 709
+ + L G T+GIVG GRIG AVA + A R++ ++ P + E G
Sbjct: 143 L--IRNQVQPMQLEGKTLGIVGLGRIGSAVASKCSAAFQMRVLAYDPYVLPSQAEAVGGT 200
Query: 710 VKVSFDELLTQSDFV 754
+ + D LL +SDFV
Sbjct: 201 LVENLDYLLAESDFV 215
>UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:
T12C24.9 - Arabidopsis thaliana (Mouse-ear cress)
Length = 323
Score = 73.3 bits (172), Expect = 6e-12
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 2/147 (1%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
PSL+++ SVG DHID+A CK+RG+ I + RR+P A
Sbjct: 73 PSLQILVCTSVGIDHIDLAACKRRGIVITNAGNAFSDDVADCAVGLLISVLRRIPAADRY 132
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
++G W + + G ++G VGIVG G IG VA+R+++F I Y +RS +K
Sbjct: 133 VRSGNWAKFG-DFQLGSKVSGKRVGIVGLGSIGSFVAKRLESFGCV-ISYNSRS----QK 186
Query: 698 ETGAVKVSFD--ELLTQSDFVICCAXL 772
++ + D L +D ++ C L
Sbjct: 187 QSSPYRYYSDILSLAENNDVLVLCCSL 213
>UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n=4;
Trichocomaceae|Rep: Glyoxylate/hydroxypyruvate reductase
- Aspergillus oryzae
Length = 350
Score = 73.3 bits (172), Expect = 6e-12
Identities = 43/134 (32%), Positives = 61/134 (45%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T D EL+ + +LK + G+D +D+ C +RG+RI TP V
Sbjct: 74 TGPFDKELIHSLPLTLKFICLNGAGYDGMDIQTCTERGIRISNTPKVVADATADVAMFLM 133
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
R+ + + G W P G G +GI+G G IGQA+A R +AF +
Sbjct: 134 LGALRQAMIPLVSIRNGQWKGDTP---LGRDPGGKVLGILGMGAIGQAIAHRARAFGL-K 189
Query: 659 IIYFNRSHRPEEKE 700
IIY NRS +KE
Sbjct: 190 IIYHNRSKLARDKE 203
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 72.9 bits (171), Expect = 8e-12
Identities = 45/150 (30%), Positives = 74/150 (49%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
KI +++D+ P LK++AT S G DHIDVA +G+ + P
Sbjct: 54 KISKDVIDSL-PDLKLIATRSTGFDHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLA 112
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+R++ E I + G + + + G LAG T+G++G GRIG A + F + +
Sbjct: 113 LARKLRETIDNVEKG---VYKTSNLRGIELAGKTLGVIGTGRIGARTALLARCFGMDVVC 169
Query: 665 YFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
Y R ++ + G + F+ELL+ SDF+
Sbjct: 170 YDARQNQ-ILIDAGIKYLDFNELLSVSDFI 198
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 72.9 bits (171), Expect = 8e-12
Identities = 45/154 (29%), Positives = 73/154 (47%)
Frame = +2
Query: 233 SPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG 412
+P+ +E KEV G+ + D L +LK+++ + +G D + + CK+RG
Sbjct: 41 TPLEVSEFAKEVDGI------IAGTEDLTPLIHKNRNLKIISRVGIGLDSVPLNLCKERG 94
Query: 413 VRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVG 592
+ + YTPD +R+V A E KTGGW + TG L +T+G
Sbjct: 95 IAVAYTPDAVTMAVAELTIGLMISSTRKVFLAHQELKTGGW-----SRFTGKRLGESTIG 149
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEE 694
IVG GR+G V R + F + I+ + + +E
Sbjct: 150 IVGVGRVGLNVIRILSEFRPKMILINDLKDKKKE 183
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 72.9 bits (171), Expect = 8e-12
Identities = 50/158 (31%), Positives = 78/158 (49%), Gaps = 2/158 (1%)
Frame = +2
Query: 287 YCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXX 466
+C +T I +LL + P L++V +G D ID+ +++GV + T
Sbjct: 55 FCLVTTAITEKLLQES-PKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHT 113
Query: 467 XXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAF 646
RR+ A + G W+ + L+G TVGI+GFG IG+ VA+R++ F
Sbjct: 114 IMLILAALRRLALADQSMREGKWI-YTELRPLCRKLSGKTVGILGFGNIGRNVAQRLQGF 172
Query: 647 NTERIIYFNRSHRPEEKE--TGAVKVSFDELLTQSDFV 754
+ E IIY + P E E A VSFDEL+ +S+ +
Sbjct: 173 DVE-IIYHDPFRAPPEVEDRLKATYVSFDELIKRSNIL 209
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 72.9 bits (171), Expect = 8e-12
Identities = 47/154 (30%), Positives = 69/154 (44%)
Frame = +2
Query: 293 SLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXX 472
++ K D EL++ S K + G+D ID C KRG+ + PD
Sbjct: 63 AVAGKFDAELINHLPESCKYIFHNGAGYDPIDTEACAKRGIIVTNAPDPVTDATADLAVL 122
Query: 473 XXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
R + AI G + G G T+GI+G GRIG+AV +R + F
Sbjct: 123 LLLGALRNLNPAIRSLYAGTFKQGVG---FGHDPQGKTLGILGMGRIGRAVKQRCEPFGI 179
Query: 653 ERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
+ +Y NR + GA VSF++LLT+SD +
Sbjct: 180 -KTVYNNRRPLSADLSAGAEYVSFEKLLTESDII 212
>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 315
Score = 72.1 bits (169), Expect = 1e-11
Identities = 43/139 (30%), Positives = 71/139 (51%)
Frame = +2
Query: 275 VNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXX 454
+ I S K+ L+ A P+L++++ + VG+D +DV +R +R+ +TP V
Sbjct: 45 IRAIVGSGESKVPRSLM-AQLPALEMISIMGVGYDGVDVTAALERNIRVTHTPGVLNDDV 103
Query: 455 XXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARR 634
+RR+P+A ++G W P + ++G +GIVG GRIGQA+A R
Sbjct: 104 ADLAIGLMLSVARRIPQADQYVRSGRWPE-GPMPLARK-VSGERLGIVGLGRIGQAIATR 161
Query: 635 VKAFNTERIIYFNRSHRPE 691
+AF + Y RS + E
Sbjct: 162 AEAFGMS-VAYTARSRKAE 179
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 72.1 bits (169), Expect = 1e-11
Identities = 43/148 (29%), Positives = 69/148 (46%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
+ID LLDA P+ +++ +++VG D +D +RG+ + P
Sbjct: 62 RIDAALLDAM-PNCRLIQSVAVGFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLH 120
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
R + + GGW P + G L+ TV I+GFG IG+AVARR+ F E ++
Sbjct: 121 LLRHYAAGHRKVEQGGW---GPEGLRGRDLSALTVAILGFGNIGRAVARRLDGFGAEIVV 177
Query: 665 YFNRSHRPEEKETGAVKVSFDELLTQSD 748
H P E G V+ +E + ++D
Sbjct: 178 -----HDPFPSEPGRQYVALEEAVARAD 200
>UniRef50_Q9A6E7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenases family protein; n=3;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenases family protein - Caulobacter crescentus
(Caulobacter vibrioides)
Length = 319
Score = 71.7 bits (168), Expect = 2e-11
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L ++A +SVG+D +DV CK G+ + ++ + R + E
Sbjct: 71 PRLGLIACVSVGYDGVDVPWCKAHGIAVTHSTGLNAADVADHAVGLVLAAWRGIVEGDQR 130
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
+ G W S A PGL G G+VG G IG+AVA R+KAF+ ++ ++ P K
Sbjct: 131 LRGGHW-SHAERMAPRPGLRGRKAGVVGLGHIGEAVAARLKAFDM-KVAWW----APRPK 184
Query: 698 ETGAVKV-SFDELLTQSDFVICCA 766
ET + S L SD +I CA
Sbjct: 185 ETDYPRADSLMALARDSDVLIVCA 208
>UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 317
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = +2
Query: 248 AELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGY 427
A L + AGV I + EL+ AA P L++++ VG D ID+A ++RG+R+
Sbjct: 41 AFLAEHGAGVRAIATRGDLGANAELI-AALPKLEIISCYGVGTDAIDLAAARERGIRVTN 99
Query: 428 TPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFG 607
TPDV R + ++G W +T L G VG+VGFG
Sbjct: 100 TPDVLTGDVADLGVGLALAMMRHIGAGDAYVRSGAWSDGDMPLVT--RLYGKRVGVVGFG 157
Query: 608 RIGQAVARRVKAFNTERIIYFNRSHRPE 691
RIG +ARR+ F+ E + YF+ + R +
Sbjct: 158 RIGTTIARRLSGFDVE-LGYFDVAPRTD 184
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 71.7 bits (168), Expect = 2e-11
Identities = 46/207 (22%), Positives = 92/207 (44%), Gaps = 1/207 (0%)
Frame = +2
Query: 137 GRYQIYVTRSD-MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKID 313
G + V SD + G+++LK+ D+++ + + EL++++ G + + ++
Sbjct: 14 GEIDMKVLVSDSLSNEGLEILKEHFDIDVC---TGLCEDELVEKIKGYDALVIRSGTQVT 70
Query: 314 TELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSR 493
+++AA +LK++ VG D++DV K+G+ + P+ SR
Sbjct: 71 QRIIEAAD-NLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSR 129
Query: 494 RVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN 673
+P+A K W G + G T+G++G GRIG VA+R + Y
Sbjct: 130 NIPQANASLKAR---EWKRNKFMGVEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDP 186
Query: 674 RSHRPEEKETGAVKVSFDELLTQSDFV 754
E G + +E+ ++D++
Sbjct: 187 FISEKRAMELGVKLATVNEIAKEADYI 213
>UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex
aeolicus|Rep: D-lactate dehydrogenase - Aquifex aeolicus
Length = 334
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/174 (31%), Positives = 82/174 (47%)
Frame = +2
Query: 233 SPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG 412
S VP EL K A + ++ + DK+ ELL P LK++ T SVG DHID+ CKK+G
Sbjct: 33 SKVPENELKK--AELISVF--VYDKLTEELLSKM-PRLKLIHTRSVGFDHIDLDYCKKKG 87
Query: 413 VRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVG 592
+ + + P +R+ K + + + L T+G
Sbjct: 88 ILVTHIPAYSPESVAEHTFAMILTLVKRLKRIEDRVKKLNFSQ--DSEILARELNRLTLG 145
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
++G GRIG VA AF +++ ++ R + KE G V S DELL +SD +
Sbjct: 146 VIGTGRIGSRVAMYGLAFGM-KVLCYDVVKREDLKEKGCVYTSLDELLKESDVI 198
>UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9301|Rep: Putative
dehydrogenase - Prochlorococcus marinus (strain MIT
9301)
Length = 318
Score = 71.3 bits (167), Expect = 2e-11
Identities = 42/192 (21%), Positives = 89/192 (46%), Gaps = 1/192 (0%)
Frame = +2
Query: 185 VQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATI 364
++LL+ +V P+ +L +G+ + D+ID LD + +L++++
Sbjct: 15 IELLEKNFEVISNQNDKPLTYEKLKFLCKDAHGVMVFMPDRIDKNFLDNS-KNLEIISGA 73
Query: 365 SVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSW 544
G D+ID+ EC KR ++ PD+ SR + ++ + W
Sbjct: 74 LRGFDNIDLEECIKRNIKFTMIPDLLASPTAELTLGLLIGLSRNLLIGDEYVRSEKFKGW 133
Query: 545 APTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY-FNRSHRPEEKETGAVKVS 721
P + + G+ G V ++G G++G VAR++K FN + Y + +E++ +
Sbjct: 134 EPKFFSN-GIEGKNVCLLGMGKLGVEVARKIKGFNVKLFYYDLQKLDSIDEQQLNTKYLE 192
Query: 722 FDELLTQSDFVI 757
++L ++D+++
Sbjct: 193 LNDLFEKADYLV 204
>UniRef50_Q1E2M0 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Coccidioides immitis
Length = 358
Score = 57.6 bits (133), Expect(2) = 3e-11
Identities = 32/69 (46%), Positives = 38/69 (55%)
Frame = +2
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVS 721
W G G T+GI+G G IG+ VARR + F IIY NR P E E A VS
Sbjct: 144 WFGKTTLGHDPRGRTLGILGMGGIGREVARRARVFGMN-IIYHNRRRLPRELEGDATYVS 202
Query: 722 FDELLTQSD 748
FD+LL +SD
Sbjct: 203 FDDLLCKSD 211
Score = 33.5 bits (73), Expect(2) = 3e-11
Identities = 16/51 (31%), Positives = 25/51 (49%)
Frame = +2
Query: 278 NGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
+ + +T D E+L SLK + G+D+IDV C ++G G T
Sbjct: 98 SNVSTKVTGPFDEEMLSVLPNSLKFICHNGAGYDNIDVDACTEKGQWFGKT 148
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 70.9 bits (166), Expect = 3e-11
Identities = 48/191 (25%), Positives = 87/191 (45%)
Frame = +2
Query: 182 GVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVAT 361
G+Q L + D N+ + + + LL + G+ ++ ++++ A +LKV+A
Sbjct: 15 GLQSLLNHSDFNV-DIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEKAS-NLKVIAR 72
Query: 362 ISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS 541
VG D+ID+ +G+ + PD +R +P+A K W
Sbjct: 73 AGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWNR 132
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVS 721
A G L T+G++G GRIG VA+R+++F + + Y + ++ G +
Sbjct: 133 KA---FKGVELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQLGVKLAT 189
Query: 722 FDELLTQSDFV 754
DE+ Q+DFV
Sbjct: 190 IDEIARQADFV 200
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 70.9 bits (166), Expect = 3e-11
Identities = 45/168 (26%), Positives = 84/168 (50%), Gaps = 1/168 (0%)
Frame = +2
Query: 164 SDMPESGVQLLK-DQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGP 340
S ++ ++LLK ++ DV L + + EL ++ G + + + T++I E++ A P
Sbjct: 11 SSTSQTPLELLKSNEIDVILNSHERKITTRELASDI-GNSDVLIAGTERITEEVIKNA-P 68
Query: 341 SLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEA 520
+LK+++ + VG D ++ C K G+++ YTPD SR++
Sbjct: 69 NLKLISRVGVGLDGVNFELCNKYGIKVTYTPDAPTMAVAELCVGIILDLSRKISYTDRNV 128
Query: 521 KTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+ G W + G L G TVGI G GRIG+++ + +FN + ++
Sbjct: 129 RKGVWDRY-----MGNLLYGKTVGIFGMGRIGKSLVHLLSSFNVKFLV 171
>UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic component; n=1; Nitratiruptor
sp. SB155-2|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic component - Nitratiruptor sp.
(strain SB155-2)
Length = 314
Score = 70.5 bits (165), Expect = 4e-11
Identities = 48/151 (31%), Positives = 70/151 (46%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
KID +L+ P+L+ + T S G DHID+ ECKKRG+ +
Sbjct: 50 KIDRLVLELL-PNLRYIQTRSTGFDHIDLEECKKRGIIVSNVQGYAGPPVAEFAFSLLLN 108
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
SR+ AI AK G +V + G L ++GIVG G IG+ +AR F +
Sbjct: 109 ISRKTDIAIARAKEGSFVY---KDLLGFELFEKSIGIVGLGTIGKQMARIASGFGMKTKA 165
Query: 665 YFNRSHRPEEKETGAVKVSFDELLTQSDFVI 757
Y + K+ K S++ELL SD ++
Sbjct: 166 YTHHFDETFCKQYNIEKCSYEELLQTSDVIM 196
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 70.5 bits (165), Expect = 4e-11
Identities = 61/208 (29%), Positives = 95/208 (45%), Gaps = 4/208 (1%)
Frame = +2
Query: 143 YQIYVTRSDMPESGVQLLKD--QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDT 316
Y++ +T + P +G+++L+D + +V++ + SP E LK G+ I S T K+
Sbjct: 2 YRVLITDNLSP-AGLKILEDNPEIEVDIRSGLSPEEVREALKSADGI--IIRSAT-KLTE 57
Query: 317 ELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRR 496
E+L P LK + VG D+ID A + G+ + TP +R
Sbjct: 58 EVLKGQ-PRLKAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARN 116
Query: 497 VPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY--F 670
+ A K G W +TG +AG T+ I+G GRIG +VA R + + I Y F
Sbjct: 117 IGPAYATMKEG---KWERKKLTGTQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPF 173
Query: 671 NRSHRPEEKETGAVKVSFDELLTQSDFV 754
+ R E K DEL+ DF+
Sbjct: 174 MSAERAAEYGIELYK-EVDELVKHCDFL 200
>UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyces
maris DSM 8797|Rep: Putative dehydrogenase -
Planctomyces maris DSM 8797
Length = 322
Score = 70.5 bits (165), Expect = 4e-11
Identities = 62/213 (29%), Positives = 101/213 (47%), Gaps = 3/213 (1%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQLLK-DQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLT 301
MSAK Y++ +T P+ V+ + + D + P A+L++ +GV+ I +
Sbjct: 1 MSAK--YRVLITDRAWPDCEVEKRELARVDAEVIEAPPGADEAKLVECASGVDAI-ATCW 57
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
++ ++DAA P K +A + +G D+IDVA + + PD
Sbjct: 58 AQVTQAVIDAA-PDCKTIARLGIGLDNIDVAYATSLKIPVTNVPDYCIPEVADHAIGLML 116
Query: 482 XXSRRVPEAIHEAKTGGW-VSWAPTWMTGPGLAGA-TVGIVGFGRIGQAVARRVKAFNTE 655
R + + K G + +S AP P G+ T+G+ GFG GQAVA R +AF +
Sbjct: 117 ASLRNIAFLNQQIKQGIYDLSAAPV----PRRVGSLTLGLFGFGLTGQAVAERARAFGMQ 172
Query: 656 RIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
+I N S + TG V+F+ELL +SD +
Sbjct: 173 -VIATNSS--GNDYGTGTRMVAFEELLEESDVI 202
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 70.5 bits (165), Expect = 4e-11
Identities = 47/172 (27%), Positives = 79/172 (45%)
Frame = +2
Query: 239 VPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVR 418
+ RAE+L V G+ ID +L+ A LKV+A G D ID++ RG++
Sbjct: 32 ITRAEILTIVDKYEGLMVRSKTAIDEDLIGRAS-RLKVIARAGAGLDKIDLSAANARGIK 90
Query: 419 IGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIV 598
+ P+ V A E K W A G L VG++
Sbjct: 91 VLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWEVKNFAWKREANR---GVELMDKVVGVI 147
Query: 599 GFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
G+G +G+A A+R+ +F + +I ++R RP+ + A +VS DE+ +++ +
Sbjct: 148 GYGNMGKAFAKRLSSFGCKDVIAYDR--RPDRGDEYARQVSMDEVFERAEII 197
>UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=13; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Brucella abortus
Length = 324
Score = 70.1 bits (164), Expect = 6e-11
Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = +2
Query: 185 VQLLKDQCDVN-LWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVAT 361
VQ L D+ +V + + + ++ +K+V G+ + K+ +L+DA P+L+++
Sbjct: 19 VQRLSDEFNVQRMARGDTALLGSDWVKDVKGIASM-----SKVSADLIDAL-PNLEIIGN 72
Query: 362 ISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS 541
VG+D +D V + TPDV R + +A + G W
Sbjct: 73 FGVGYDAVDARHAGANNVMVTNTPDVLTEEVADTTIGLLIDTVRELSKAQEFLRRGEWGK 132
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
++ L G VGI G GRIG+AVARR++AF I Y NR
Sbjct: 133 QVRYPLSKLSLRGRKVGIFGLGRIGKAVARRIEAFGLP-IAYHNR 176
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 70.1 bits (164), Expect = 6e-11
Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 2/209 (0%)
Frame = +2
Query: 134 KGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKID 313
KG + + D+P+ ++L++ V + + P EL + +G+ K+
Sbjct: 6 KGSVMLVLIADDLPDVCNEILQN-AGVEVLKKTGLKP-PELDAVIKMCDGVIVRSNTKLT 63
Query: 314 TELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSR 493
+L+ + LK + VG D+IDV K+G+ + TP SR
Sbjct: 64 APVLEKS-EKLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSR 122
Query: 494 RVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY-- 667
VP+A K G W TG L G T GI+G GR+G+ VA+R A + I Y
Sbjct: 123 FVPQACASVKEG---KWEKKKFTGQQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDP 179
Query: 668 FNRSHRPEEKETGAVKVSFDELLTQSDFV 754
F + + VK + +LL Q+D++
Sbjct: 180 FITTEISSQYNIHIVK-NLRDLLAQADYI 207
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 70.1 bits (164), Expect = 6e-11
Identities = 51/174 (29%), Positives = 76/174 (43%)
Frame = +2
Query: 233 SPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRG 412
S +P A+L + G G + T + AA P LKV+A VG+D +DV + G
Sbjct: 70 SNIPDADLNALLEGAAGWIVG--QRAVTRDVLAAHPQLKVIARRGVGYDRVDVDAARDLG 127
Query: 413 VRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVG 592
+ RR+ + G W + G L G TVG
Sbjct: 128 RVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW-----RVLVGADLTGKTVG 182
Query: 593 IVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
++GFGRIG+ VARR+ F+ ++ S P+ + G V+ DEL+ +SD V
Sbjct: 183 LIGFGRIGRQVARRLSGFDVTVLV---TSRTPDPEAAGVTFVALDELIARSDVV 233
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 69.7 bits (163), Expect = 7e-11
Identities = 57/200 (28%), Positives = 85/200 (42%), Gaps = 4/200 (2%)
Frame = +2
Query: 167 DMPESGVQLLKD---QCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAG 337
D+ V++L++ + DV + +P + R V +G+ K+ +LLD A
Sbjct: 10 DLSPEAVRILQEAGLEVDVKVGLKPDQLERI-----VGDYDGLAVRSATKVTAQLLDKAA 64
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
LKV+ VG D++D+A +RGV + TP SR V A
Sbjct: 65 -RLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGS 123
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE-E 694
K G W G LAG T+G+VG G IG + R A R++ F+ E
Sbjct: 124 VKAG---KWEKKRFQGHELAGRTLGVVGIGNIGSVLVARAVALGM-RVVAFDPFISAEAA 179
Query: 695 KETGAVKVSFDELLTQSDFV 754
+ GA V D L ++D V
Sbjct: 180 AKLGASLVDLDTLWREADVV 199
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 69.3 bits (162), Expect = 1e-10
Identities = 46/171 (26%), Positives = 80/171 (46%), Gaps = 1/171 (0%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
+ +L+KE+ G+ K+ ++ A P+L+VV G D+ID+ ++GV +
Sbjct: 37 KEKLIKELQNHEGLIVRSETKVTADVF-ACCPNLRVVGRAGTGVDNIDLEAATRKGVIVL 95
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP +R V +A+ K G W +G L+G T+ ++G
Sbjct: 96 NTPGGNSISACELTCALISNLARNVTQAVQSLKDG---RWDRKLYSGFELSGKTLAVLGM 152
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKE-TGAVKVSFDELLTQSDFV 754
GRIG+ V RR++A+ R+I F+ E+ K S DE+ +D++
Sbjct: 153 GRIGREVTRRMQAYGM-RVIAFDPLLTSEDANYLNVEKFSLDEIWPMADYI 202
>UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Acidiphilium cryptum
(strain JF-5)
Length = 332
Score = 69.3 bits (162), Expect = 1e-10
Identities = 45/140 (32%), Positives = 64/140 (45%)
Frame = +2
Query: 269 AGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXX 448
A + GI D L+ A P+L+++A VG+D +D K GV + TPDV
Sbjct: 44 AEIRGIVTRGRRPTDAALI-ARLPALELIANFGVGYDTVDAVAAAKHGVIVTNTPDVLSD 102
Query: 449 XXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVA 628
R +P A + G W+ A + G L G +GI G GRIGQ +A
Sbjct: 103 EMGDFTVGLLLATIRTLPAAERFLRAGKWLHDA--FPLGNSLRGRRIGIAGMGRIGQVIA 160
Query: 629 RRVKAFNTERIIYFNRSHRP 688
RR+ F+ I Y +R+ P
Sbjct: 161 RRLSGFDLP-ISYHSRNRVP 179
>UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome C of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 339
Score = 69.3 bits (162), Expect = 1e-10
Identities = 45/149 (30%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Frame = +2
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D EL+ SLK +A G+D IDV E KRG+++ PD+
Sbjct: 67 DEELISHFPSSLKYIAHQGTGYDQIDVDELNKRGIQLSNCPDIVTKSTADMNIFLMLGAM 126
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGA--TVGIVGFGRIGQAVARRVKAFNTERII 664
R G W + G A + +GI+G G IG+AV R +F E+I+
Sbjct: 127 RNFEAGRRNLIAGKWPAGGLGAGVEAGWAPSRKVLGIIGMGNIGRAVRDRAVSFGFEKIV 186
Query: 665 YFNRSH-RPEEKETGAVKVSFDELLTQSD 748
Y++RS PE ++ S +EL+ SD
Sbjct: 187 YYSRSKLTPELEKDCEYVASLEELVAASD 215
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 68.9 bits (161), Expect = 1e-10
Identities = 47/191 (24%), Positives = 82/191 (42%)
Frame = +2
Query: 182 GVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVAT 361
G+ +LK V++ + + AE++ V + I K+ TE + AG LK++
Sbjct: 42 GIDILKQVAQVDV---KTGLSEAEIIDIVPEYDAIMLRSATKV-TEKIIQAGSQLKIIGR 97
Query: 362 ISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS 541
VG D+IDV ++G+ + +P+ +R +P+A K
Sbjct: 98 AGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKES---K 154
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVS 721
W G + T+G+VG G+IG VA KA + + Y + + G V
Sbjct: 155 WERKQFIGTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVD 214
Query: 722 FDELLTQSDFV 754
D L +++DF+
Sbjct: 215 LDLLFSEADFI 225
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 68.9 bits (161), Expect = 1e-10
Identities = 43/170 (25%), Positives = 77/170 (45%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
+ EL+ E+ G+ K+ ++++AA L+VV G D++D+ ++G+ +
Sbjct: 38 KEELIAELQDCEGLIVRSATKVTADVINAA-EKLQVVGRAGTGVDNVDLEAATRKGILVM 96
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP+ +R++P+A K G W G L G T+GI+G
Sbjct: 97 NTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG---KWERKKFMGTELNGKTLGILGL 153
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
GRIG+ VA R+++F + I Y G ++ +E+ DF+
Sbjct: 154 GRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFI 203
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 60/202 (29%), Positives = 88/202 (43%)
Frame = +2
Query: 149 IYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
IYVT PE +Q L +V L P+ P +E+ EV V I E++
Sbjct: 4 IYVTSPIHPEV-LQALSSVGEVRLGYGPNAAPYSEIQNEVDAV----FLRGGHISAEMI- 57
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P L++VA G+D++D + GV + TP SR+V A
Sbjct: 58 AASPKLRIVARHGAGYDNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLA 117
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
+ + W + +TG L G T+G++GFG IG+ VA +AF + +
Sbjct: 118 TDQTRNNIWAQDRLS-LTGIELEGRTLGLIGFGDIGRHVAPVAEAFGMKVLATDPAYDTS 176
Query: 689 EEKETGAVKVSFDELLTQSDFV 754
+K V D LLTQ+D V
Sbjct: 177 FDKRL----VDLDTLLTQADVV 194
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 68.5 bits (160), Expect = 2e-10
Identities = 42/155 (27%), Positives = 67/155 (43%)
Frame = +2
Query: 308 IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXX 487
I +++ DA P L++V G ++++V E KRG+ +
Sbjct: 85 ISSKVFDAM-PKLRIVGVSRAGLENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAE 143
Query: 488 SRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
R + A + K GGW P L G VG+VGFG IG+ VA+++ F R++Y
Sbjct: 144 CRNIARAHYSIKNGGWRKEFSNSDWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVY 203
Query: 668 FNRSHRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
+ G + V + L +SDF+ A L
Sbjct: 204 DPFVDEETIRGAGCIPVDKETLFKESDFISLHARL 238
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 68.5 bits (160), Expect = 2e-10
Identities = 50/185 (27%), Positives = 78/185 (42%)
Frame = +2
Query: 200 DQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHD 379
D D + + P A + + V G + + ++ E+++AA SLKVV +G D
Sbjct: 23 DAVDATVETIAAKEPEA-VARAVDGADALIVDAGTQVTAEVIEAAD-SLKVVGRAGIGMD 80
Query: 380 HIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWM 559
+I V GV + PD RR+P K G W WA
Sbjct: 81 NIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKRGEW-KWA-VGQ 138
Query: 560 TGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLT 739
LAG+TVG+V FG++ A +++ F+ + I Y + + G V+ + LL
Sbjct: 139 PIRRLAGSTVGLVAFGKLASRFAAKLRGFDIDVIAYDPYAPEYRMGDLGVESVTLETLLG 198
Query: 740 QSDFV 754
SD V
Sbjct: 199 DSDIV 203
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAA---GPSLKVVATISVGHDHIDVAECKKRGVRI 421
ELL ++ + + K+ E++DAA G LK++ VG D+IDV + +G+ +
Sbjct: 34 ELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGLTV 93
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
TP+ SR + A + G W A TG + G T+G++G
Sbjct: 94 NNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKA---YTGTEIFGKTLGLIG 150
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
FGRI + VA+R +A ++IY + + ++ + LL ++DFV
Sbjct: 151 FGRIAREVAKRAEALGM-KVIYNDICGKVVGYDSYEFYDDINGLLREADFV 200
>UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3;
Bacteria|Rep: Glycerate dehydrogenase - Treponema
denticola
Length = 322
Score = 68.1 bits (159), Expect = 2e-10
Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 6/193 (3%)
Frame = +2
Query: 194 LKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKI--DTELLDAAGPSLKVVATIS 367
LK ++ ++++ S E KE V LT+K+ E++D+ P LK + ++
Sbjct: 25 LKSVSNLTIYDKTSAEELLERCKEADAV------LTNKVVFSKEIMDSL-PRLKYIGVLA 77
Query: 368 VGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWA 547
G++ +D+ + + + + P V E E G W S +
Sbjct: 78 TGYNVVDIEAARAKNICVTNIPSYSTDSVAQLVFALIFHFYWHVKEHSDEVMGGKW-SAS 136
Query: 548 PTWMTGP----GLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK 715
P + L+ T+GIVGFG IGQAVA+ A N ++IYFNRS + + A +
Sbjct: 137 PHFCYHSFDIRELSDKTMGIVGFGNIGQAVAKIALAMNM-KVIYFNRSKKNIKGLEEAKQ 195
Query: 716 VSFDELLTQSDFV 754
VS DEL + SD +
Sbjct: 196 VSLDELFSSSDII 208
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 3/155 (1%)
Frame = +2
Query: 311 DTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXS 490
D +D AGP+L +A +G D+ID+A +RG+ + TPD +
Sbjct: 59 DGAWMDRAGPTLMAIARPGIGVDNIDLAAATERGILVINTPDGPTESTAEHAVALVLALA 118
Query: 491 RRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYF 670
++V A H +T G W+ + G + G T+G+VG GRIG+ VA+ + R+ +
Sbjct: 119 KQVVAADHRFRTAG---WSAARLRGVEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAY 175
Query: 671 NRSHRPEE-KETGAVKV-SFDELLTQSDFV-ICCA 766
+ E V V + D LL QS+F+ + CA
Sbjct: 176 DPLAPAEAFAALDVVHVETLDNLLPQSEFLTLHCA 210
>UniRef50_Q54DP1 Cluster: Gluconate 2-dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Gluconate
2-dehydrogenase - Dictyostelium discoideum AX4
Length = 334
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
E + + NG+ S+ KID +L A P L+ V+ ISVG+D+ D+ R + + +T
Sbjct: 47 EFYEAIKTANGLIGSVF-KIDENVLSKA-PFLECVSAISVGYDNYDLVVLNDRKIPLMHT 104
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
P+V +R++ + G W G + VGI+G GR
Sbjct: 105 PNVLNDSMADIMMGLMITVARKLAYCDKRMRNGEWNGPLDKSWFGLEVHHKKVGIIGMGR 164
Query: 611 IGQAVARRVKAFNTERIIYFNRS-HRPEEKETGAVKVSFDELLTQSDFV 754
IG+ +A+R + + Y++RS H E+ A D +L+ SDF+
Sbjct: 165 IGEVLAKRCRMGFDMEVAYYSRSRHLKVEELYDAKHQDLDTILSTSDFI 213
>UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl274c;
n=1; Paracoccidioides brasiliensis|Rep: Hydroxyacid
dehydrogenase protein Ynl274c - Paracoccidioides
brasiliensis
Length = 299
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/152 (32%), Positives = 67/152 (44%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T D ELL SLK + G+D+ID+ K+G+ + TP
Sbjct: 39 TGPFDAELLGVLPKSLKFICHNGAGYDNIDIPSFTKKGIEVSSTPRAVNNATADIAVFLM 98
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
R+ W+ G G +GI+G G +G A+ R +AF R
Sbjct: 99 IGALRQA-----------WIPQQAIRALGHDPQGKVLGILGMGGVGMAL--RAQAFGM-R 144
Query: 659 IIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
IIY NR+ E+E G V VSFD+LLTQSD +
Sbjct: 145 IIYHNRNRINPEQE-GMVYVSFDDLLTQSDII 175
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 67.7 bits (158), Expect = 3e-10
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 3/198 (1%)
Frame = +2
Query: 170 MPESGVQLLK--DQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPS 343
M E G+ +L+ + DV++ +QP +L + V I S T +I EL++ A P
Sbjct: 9 MHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAV--IVRSRT-RITAELIENA-PR 64
Query: 344 LKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAK 523
LKV+ G D+IDV RG + TP +R +P+A +
Sbjct: 65 LKVIGRAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMR 124
Query: 524 TGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKE- 700
G W G L T+GI+G G+IG VA R + + ++ + PE
Sbjct: 125 EG---RWDKKRFMGTELFHQTLGIIGLGKIGSIVADRALSMKMD-VLGHDPYIIPEAAAI 180
Query: 701 TGAVKVSFDELLTQSDFV 754
G V DELL +SDF+
Sbjct: 181 LGVEWVPLDELLARSDFL 198
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 67.3 bits (157), Expect = 4e-10
Identities = 48/163 (29%), Positives = 75/163 (46%), Gaps = 2/163 (1%)
Frame = +2
Query: 278 NGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXX 457
+G+ +I ++LDAA P L V + G D+ID+ + GV + P +
Sbjct: 45 HGLAVRYPAQITADVLDAA-PQLLAVLSSGRGVDNIDIPAASRAGVVVANNPGLGGKPVS 103
Query: 458 XXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRV 637
+R + +A TG W T L G T+GIVG G +G +ARR
Sbjct: 104 EHALGLLIMITRDLTAVARDAMTGAWEKRLTTRRVE--LTGGTLGIVGCGNVGGWMARRA 161
Query: 638 KAFNTERIIYFNRSHRPEE-KETGAVKV-SFDELLTQSDFVIC 760
A R++ ++ E+ + GA KV + D+LL ++DFV C
Sbjct: 162 SAGFQMRVLAYDPYVSAEQMAQVGATKVDNLDKLLAEADFVSC 204
>UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8;
Bradyrhizobiaceae|Rep: 2-hydroxyacid dehydrogenase -
Bradyrhizobium japonicum
Length = 317
Score = 66.9 bits (156), Expect = 5e-10
Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 2/150 (1%)
Frame = +2
Query: 236 PVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGV 415
PV E+ G+ + + E +D P+L + G+D +D+ R +
Sbjct: 32 PVREVFSADELGGIRAMLTGGGTPLGAEAMDLF-PNLGAIVCYGTGYDGVDLKAAAARDI 90
Query: 416 RIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGP--GLAGATV 589
+G++P +RR+ A ++G W + P+ M P G+ G +
Sbjct: 91 AVGHSPGANAASVADIAMTLMLATTRRILVADQYVRSGDWAASKPSPMMRPQAGMPGRRI 150
Query: 590 GIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
G+ G G IG+ +A R AF +E + YF+RS
Sbjct: 151 GVYGMGEIGRKIAARCAAFESE-VGYFSRS 179
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 66.9 bits (156), Expect = 5e-10
Identities = 46/166 (27%), Positives = 70/166 (42%)
Frame = +2
Query: 257 LKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPD 436
L+ + + + KID ELL A L+++ T + G DHID+ +K GV + +TP
Sbjct: 38 LEHLVSAHALIIRSRTKIDEELLKKAR-QLQLIVTCTSGFDHIDLEATQKWGVTVMHTPT 96
Query: 437 VXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIG 616
+ A K G W +TG LAG GIVG GRIG
Sbjct: 97 ANIESAAQLTWGLVLSCVNNIQAAHKMVKAG---EWNRDQITGIELAGRNYGIVGLGRIG 153
Query: 617 QAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
VA +AF + Y + ++S++E+L +D +
Sbjct: 154 SRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSYEEVLKTADVI 199
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 66.9 bits (156), Expect = 5e-10
Identities = 46/174 (26%), Positives = 79/174 (45%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
++ +T S P+ G LL+ +V +PS P+ EL +A N + + E+L
Sbjct: 14 KVLITDSVHPQCGRLLLQHGFEVT--EKPSLSPK-ELHAIIADYNILIVRSATSLPAEVL 70
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
A L+++ G D+ID+ ++G+ + TP +R +P+
Sbjct: 71 -AKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQ 129
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY 667
A+ + K G W G L G T+ ++G GR+G+ VA R++AF I Y
Sbjct: 130 AMADLKQGNWNKHL---YAGIELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAY 180
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 66.9 bits (156), Expect = 5e-10
Identities = 46/174 (26%), Positives = 77/174 (44%)
Frame = +2
Query: 236 PVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGV 415
P+ EL + V+ + + D + + + A P LK +A VG D+ID+ + G+
Sbjct: 38 PMTFDELSARLGDVDAVIAGV-DTWNERVFNLA-PRLKAIARFGVGVDNIDIDAAHRHGI 95
Query: 416 RIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGI 595
+ P RR+P +H+A GG +W G L G VG+
Sbjct: 96 AVTNAPGGNANAVAELTLGLILSAMRRIPY-LHDALRGG--AWDR--FVGQELIGRRVGL 150
Query: 596 VGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFVI 757
+GFG I + +AR++ F+ E I Y + + G DE+L+ SD ++
Sbjct: 151 LGFGNIARKIARKLCGFDVEVIAYDKFPDQVAATKLGVRMCEMDEVLSSSDILV 204
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 66.9 bits (156), Expect = 5e-10
Identities = 54/153 (35%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
TD E+L A +LKV+A + VG D ID K+ GV I TP +
Sbjct: 57 TDPFTREVL-AGDRNLKVIARVGVGTDSIDHDAAKEFGVGISVTPGMNAETVADQTLAMI 115
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
RRV K G W T L TVG++G G IG+AV RR+ F R
Sbjct: 116 LGLMRRVVTQDQAVKAGRWDRVGEA--TPTELYRKTVGLIGAGIIGKAVIRRLLGFGV-R 172
Query: 659 IIYFNRSHRPEEKETGAVKV-SFDELLTQSDFV 754
++YF+ EK GA + S D+LL SD V
Sbjct: 173 VLYFDAM---VEKVHGAERCGSLDQLLGSSDIV 202
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 66.9 bits (156), Expect = 5e-10
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Frame = +2
Query: 155 VTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAA 334
V + ++ + L K N+ + +LL+++ G + + +D +L+ A
Sbjct: 4 VVAEKIAKAAIDLFKQDPTWNVVTPDQVAQKEQLLEQLKGADALIVRSAVFVDAAMLEHA 63
Query: 335 GPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIH 514
L+V+ VG D+I++ ++G+ + TP +R +P A
Sbjct: 64 D-QLRVIGRAGVGVDNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATE 122
Query: 515 EAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEE 694
G W + + G L G T+GIVG GRIG VARR +F ++ + P
Sbjct: 123 TMHAGKWEKKS---LQGTELRGKTLGIVGLGRIGLEVARRAASFGM-TLVAHDPYVSPAI 178
Query: 695 KETGAVKVS-FDELLTQSDFV 754
++++ DE+L +D++
Sbjct: 179 AHDAKIRLADRDEVLAVADYI 199
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Frame = +2
Query: 299 TDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXX 478
T K D +++DA P+LKV+A VG+D +DV +RG+ + TP
Sbjct: 51 TQKFDADIMDAM-PNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSEL 109
Query: 479 XXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
S+ + + W ++ G + G TVGI+GFGRIGQ VA+++ F+ +
Sbjct: 110 LAISKNLYQDSKAIHDDNW-NYRKAH-PGRDIEGKTVGILGFGRIGQQVAKKLSGFDV-K 166
Query: 659 IIYFNRSHRPEEKETGAVK-VSFDELLTQSDFVI 757
+I F+ P K+ V+ V + + +D+V+
Sbjct: 167 VIAFD----PFAKDVPGVELVDRETIFKTADYVM 196
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/154 (29%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = +2
Query: 296 LTDK-IDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXX 472
+TD D DA P+LK++A VG+D+I V K GV + TP
Sbjct: 50 MTDMAFDKNWFDAL-PNLKLIARRGVGYDNIPVESATKHGVWVTNTPGANAIAVAELAVT 108
Query: 473 XXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
R+V +A + + G +++ P + G L+G +G++G+G+I Q + + + F
Sbjct: 109 LILTVLRKVNQATNSVQKGEALTY-PASLMGHNLSGKIIGLIGYGQIAQNLEKILHGFGA 167
Query: 653 ERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
++Y S E G VS+D LL QSD +
Sbjct: 168 HVLVY---SRTKRETLYGQF-VSYDTLLAQSDII 197
>UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Paracoccus
denitrificans PD1222|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Paracoccus
denitrificans (strain Pd 1222)
Length = 314
Score = 66.9 bits (156), Expect = 5e-10
Identities = 35/118 (29%), Positives = 58/118 (49%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P+L+++A VG D +D+AE ++RG+ + TPDV RR+ E
Sbjct: 57 PALRLIAVNGVGVDAVDLAEARRRGIAVTTTPDVLSLAVAEMALGLALAAGRRIAEGDRF 116
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE 691
+ G W S + G L GI+G+GRIG+ +A ++ E ++Y R +P+
Sbjct: 117 VRAGQWSSGGKLGL-GLSLLERRAGILGYGRIGRRLADLLRGMGME-VLYTARHEKPD 172
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 2/141 (1%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L+ V S+G+D++D+ KK G+ + P + E
Sbjct: 60 PRLRFVQVASIGYDNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAE 119
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY--FNRSHRPE 691
++G W P L G T GIVG G IG+A+A R+ F IIY R E
Sbjct: 120 IRSGRW----PRITRSSDLMGKTFGIVGMGSIGRALAARLLPFKV-AIIYNDTKRMSEAE 174
Query: 692 EKETGAVKVSFDELLTQSDFV 754
E+E GA VS D LL+ SD +
Sbjct: 175 EEEYGATFVSLDRLLSDSDVI 195
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 66.5 bits (155), Expect = 7e-10
Identities = 50/200 (25%), Positives = 87/200 (43%)
Frame = +2
Query: 155 VTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAA 334
V+ + ++L+ ++ L N+ S E+LK+ + + E+++AA
Sbjct: 51 VSEEKIKNIALKLMDKDHELILHNEKSE--DIEVLKKRVETADVLILANMPLKKEVIEAA 108
Query: 335 GPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIH 514
+LK+++ G DHI++ C+K + + + R +
Sbjct: 109 -TNLKMISVAFTGIDHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLND 167
Query: 515 EAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEE 694
E + G + LAG T+G++G G IG V R KAF ++Y NRS +
Sbjct: 168 EVRNGNTKQGYSQY----DLAGKTLGVIGAGDIGTEVIRIGKAFGCNVLVY-NRSEKQHI 222
Query: 695 KETGAVKVSFDELLTQSDFV 754
KE GA + + DE+L SD V
Sbjct: 223 KELGATQTTLDEVLKNSDIV 242
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 66.5 bits (155), Expect = 7e-10
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 3/176 (1%)
Frame = +2
Query: 248 AELLKEVAGVNGIYCSLTDKIDTELLDAAGPS--LKVVATISVGHDHIDVAECKKRGVRI 421
AEL+ + G +G + D T + AAG LK VG D++D A + G+ I
Sbjct: 40 AELVDLLPGFDGWI--IGDDPATRAVFAAGVRGRLKAAVKWGVGVDNVDFAAARALGIPI 97
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
TP + +R E + GGW G LAG TV +VG
Sbjct: 98 ANTPAMFGAEVADVAVSYVTALARETFSVDREVRAGGWPK-----PCGVSLAGKTVALVG 152
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFVI-CCA 766
FG IG+A ARR+ A R+I ++ + PE + E L ++DF++ CA
Sbjct: 153 FGDIGKATARRLVAAEM-RVIAYDPRYVPEAGSEAVEPALWPERLGEADFIVFTCA 207
>UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 309
Score = 66.5 bits (155), Expect = 7e-10
Identities = 49/145 (33%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
PS+++VAT VG+D++ + K ++ TP V RR+PE+
Sbjct: 62 PSIRLVATCGVGYDNLPLPYLKANNIKASNTPGVLNDAVCELAIGMMLSLMRRIPESQEY 121
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
K+ W S AP +T LAG VGI G GRIGQ +A+R++ F +I Y S +K
Sbjct: 122 VKSSAW-SKAPFKLT-TTLAGKRVGIAGMGRIGQDLAQRLEPFKV-KIAYTGPS---PKK 175
Query: 698 ETGAVKVSFDELLTQSD--FVICCA 766
S EL SD F+ C A
Sbjct: 176 VPYTYYQSIQELAKASDVLFLACPA 200
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 66.5 bits (155), Expect = 7e-10
Identities = 42/138 (30%), Positives = 61/138 (44%)
Frame = +2
Query: 341 SLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEA 520
SLK+V VG D+ID+ E K GV + P+ R +P+A
Sbjct: 62 SLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISV 121
Query: 521 KTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKE 700
K+ W T G L G T+GIVG GRIG +A+R AF ++ K+
Sbjct: 122 KSR---EWNRTAYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPFLTEERAKK 178
Query: 701 TGAVKVSFDELLTQSDFV 754
G +F+E+L +D +
Sbjct: 179 IGVNSRTFEEVLESADII 196
>UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1;
Aegilops tauschii|Rep: Putative uncharacterized protein
- Aegilops tauschii (Tausch's goatgrass) (Aegilops
squarrosa)
Length = 573
Score = 66.1 bits (154), Expect = 9e-10
Identities = 41/127 (32%), Positives = 58/127 (45%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++D LDA PSL+ V S G DH+D+ EC++RGV + V
Sbjct: 314 RVDAAFLDAV-PSLRCVLFNSAGLDHVDLLECERRGVAVANATGVYSADVADYAVGLLID 372
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
RRV + + G W T L VGI+G G IG A+A R++AFN +
Sbjct: 373 VLRRVSASDRHVRRGHWPERGGHGFT---LGRKRVGIIGLGSIGSAIATRLEAFNC-AVS 428
Query: 665 YFNRSHR 685
Y +R +
Sbjct: 429 YHSRRQK 435
>UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 327
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/158 (34%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
K+ LLD +LK V T S G DH+D+ +K +++ V
Sbjct: 65 KLSPGLLDRM-VNLKAVVTPSSGTDHLDLDLLRKYNIKVYSAGGVNNDACADMVFNMLLS 123
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMT----GPGLAGATVGIVGFGRIGQAVARRVKAFNT 652
+RR PE I S A +T G + G+T+GIVG G IG VARR F
Sbjct: 124 VARRNPEVIQLTHRFAAQSEALVELTVQVLGHEVTGSTLGIVGMGGIGYEVARRAVGFKM 183
Query: 653 ERIIYFNRSHRP--EEKETGAVKV-SFDELLTQSDFVI 757
+ +Y++RS RP EE E A S DELL DF++
Sbjct: 184 -KTLYYSRSRRPAAEEDEVKASYCSSLDELLPHVDFLV 220
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++ ++ DAA P L +V G + IDVA +RGV + P
Sbjct: 51 QVQADVFDAA-PGLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVA 109
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
RR+P+ + + G W T+ GL G T+G+ G G IG+ VARR +A R++
Sbjct: 110 LDRRIPDNVALLRAGKWDK--KTFSEAQGLYGRTLGVAGVGSIGREVARRAQALGM-RVV 166
Query: 665 YFNRSHRPEEKETGAVKVSFD--ELLTQSDFV 754
++RS + + V+ + D L +SDF+
Sbjct: 167 AWSRSLDDRQAKLLGVERAPDLAALARESDFL 198
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/168 (28%), Positives = 75/168 (44%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
RA+ L +A +GI +ID EL+DA G LK +A G D+ID A +R + +
Sbjct: 35 RAQTLAAIADYDGIAVRTKFRIDRELIDA-GTKLKFIARAGAGLDNIDEAVALERNIHLI 93
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
P+ A E + G W G L G TVGI+G+
Sbjct: 94 NAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKG---KWDREGNRGYELKGKTVGIIGY 150
Query: 605 GRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSD 748
G +G ++AR++ F + I Y ++ + A +VS +E++ SD
Sbjct: 151 GFMGSSLARKLSGFGVQVIAY--DKYKTGFSDQYAREVSMEEIVKLSD 196
>UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula marina
DSM 3645|Rep: Dehydrogenase - Blastopirellula marina DSM
3645
Length = 321
Score = 65.7 bits (153), Expect = 1e-09
Identities = 42/142 (29%), Positives = 72/142 (50%)
Frame = +2
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P+LK+VA + +G D+IDVA C ++ + + PD +R++
Sbjct: 66 AASPNLKIVARLGIGLDNIDVAYCTQQKIPVTNIPDYCVIEVAEHTLALLLACARKIAMY 125
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
HE ++G + A M ++G T+GIVG G+IG +A R A ++I +RS +
Sbjct: 126 HHETQSGTYDLQAGPLMR--RVSGQTLGIVGLGQIGVLLAERALALGL-KVIATSRSGK- 181
Query: 689 EEKETGAVKVSFDELLTQSDFV 754
G V + +L++SD++
Sbjct: 182 --TMPGVETVDLERILSESDYI 201
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 65.7 bits (153), Expect = 1e-09
Identities = 38/141 (26%), Positives = 63/141 (44%)
Frame = +2
Query: 245 RAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIG 424
+ EL+ E+ +G+ K+ +++ A G +LK++ G D+ID GV +
Sbjct: 38 KEELVSEIPKYDGLIVRSATKVSEDVIKA-GKNLKIIGRAGTGVDNIDTVAASLHGVLVM 96
Query: 425 YTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGF 604
TP +R +P+A K G W G L G T+ I+G
Sbjct: 97 NTPGGNTLSAAEHTCALISSLARHIPQASASTKEG---KWERKQFMGNELFGKTLAIIGL 153
Query: 605 GRIGQAVARRVKAFNTERIIY 667
GRIG+ VA R++++ + I Y
Sbjct: 154 GRIGREVALRMQSYGVKTIGY 174
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 65.3 bits (152), Expect = 2e-09
Identities = 42/175 (24%), Positives = 78/175 (44%)
Frame = +2
Query: 230 PSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKR 409
P+ + E K V ++ +K+ E L+AA P+LK++ G D ID+ R
Sbjct: 36 PNGLREREDFKAVLAEAHVWVVGINKVYAEDLEAA-PNLKLIIKHGTGVDSIDLKAAAAR 94
Query: 410 GVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATV 589
G+ + P +R++ A + G W + + G + G T+
Sbjct: 95 GITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGT-----VMGKDVYGKTL 149
Query: 590 GIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
G++G G+IG+ V RR F+ + Y H EKE + +E+++++D++
Sbjct: 150 GVLGLGQIGKGVIRRASGFDMNILGYDLVHHSQFEKEYRVRAATLEEIMSEADYI 204
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 65.3 bits (152), Expect = 2e-09
Identities = 42/139 (30%), Positives = 67/139 (48%)
Frame = +2
Query: 230 PSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKR 409
P + R + L++ + G+ ++ LL+ P+L+V++T VG+D I VA + R
Sbjct: 27 PEDIARDDGLRQ--SIRGLITRSNYQVPLALLELL-PALQVISTCGVGYDGIPVAYAQAR 83
Query: 410 GVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATV 589
G+ + +TP V R +P + + G W A T LAG V
Sbjct: 84 GIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRDGRWSDSAYPLTT--SLAGKAV 141
Query: 590 GIVGFGRIGQAVARRVKAF 646
GIVG GRIG+ +A R++ F
Sbjct: 142 GIVGLGRIGRGIAARLQPF 160
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 65.3 bits (152), Expect = 2e-09
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 2/176 (1%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
+LL+ ++GV I + ++L A P L+ V G ++D+ + GV + Y
Sbjct: 59 QLLESLSGVQ-IAATQMAPFTADVL-AKSPDLRFVGVCRGGPVNVDLQAATEAGVVVSYA 116
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS-WAPTWMTGPGLAGATVGIVGFG 607
P RR+P + E K+G W + G L G+TVG+VG+G
Sbjct: 117 PGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYENAGIELEGSTVGLVGYG 176
Query: 608 RIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVK-VSFDELLTQSDFVICCAXL 772
IG+ VAR + AF ++ + +PE+ V+ V +ELL +S V A L
Sbjct: 177 AIGRIVARVLAAFGA-HVLVADPFVKPEDATADGVELVELEELLRRSSVVSLHARL 231
>UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Rhodobacterales|Rep: Putative
D-isomer specific 2-hydroxyacid dehydrogenase -
Rhodobacterales bacterium HTCC2150
Length = 313
Score = 65.3 bits (152), Expect = 2e-09
Identities = 43/146 (29%), Positives = 72/146 (49%)
Frame = +2
Query: 248 AELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGY 427
A L + AG+ + + D I +++ AA P +K+++ VG+D ID +RG+ + +
Sbjct: 34 AWLAQNGAGIEYVLTNGHDGIKPDVM-AALPDVKLISCYGVGYDAIDTTTAVERGITVTH 92
Query: 428 TPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFG 607
TP+V R + + G W + T +T VGI+G G
Sbjct: 93 TPNVLNDEVATTTIMLMLACYRNLINDDAYVRAGKWEAEGNTPLTRSA-DNRRVGILGLG 151
Query: 608 RIGQAVARRVKAFNTERIIYFNRSHR 685
RIGQA+A ++ AFN+E I Y +R+ +
Sbjct: 152 RIGQAIADKLAAFNSE-ISYHSRNQK 176
>UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase
C1773.17c; n=3; Schizosaccharomyces pombe|Rep: Putative
2-hydroxyacid dehydrogenase C1773.17c -
Schizosaccharomyces pombe (Fission yeast)
Length = 340
Score = 65.3 bits (152), Expect = 2e-09
Identities = 45/148 (30%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Frame = +2
Query: 317 ELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRR 496
E+L P+ K+ T + G++++DV + GV + TP+ R
Sbjct: 75 EMLGPLLPTCKLFVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRG 134
Query: 497 VPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
EA + G W G VGI+G G IG++ A+++ E I+Y NR
Sbjct: 135 AREAEQSLRLG---KWRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILPLGCE-IVYHNR 190
Query: 677 SH--RPEEKETGAVKVSFDELLTQSDFV 754
+ EEK GA VSFDELL+ SD +
Sbjct: 191 NRLEAEEEKRLGASFVSFDELLSSSDVI 218
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/183 (25%), Positives = 80/183 (43%)
Frame = +2
Query: 206 CDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHI 385
C+V L P E+++ + + + DK+ +++ LK++A VG D I
Sbjct: 29 CEVVLNPFGRPFTNEEIIRYASDADALIVG-NDKVPGDVIKKC-KRLKIIAKHGVGVDSI 86
Query: 386 DVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTG 565
DV + G+ + P +R + +A + K G W+ G
Sbjct: 87 DVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIK-----PVG 141
Query: 566 PGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQS 745
L+ T+GI+G G IG AVA+R ++ I+ ++ P G V DELL+++
Sbjct: 142 ISLSKKTIGIIGVGTIGTAVAKRATGYDM-NILGYDIKKNPLALGLGVKYVGLDELLSEA 200
Query: 746 DFV 754
DF+
Sbjct: 201 DFI 203
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 64.9 bits (151), Expect = 2e-09
Identities = 50/203 (24%), Positives = 86/203 (42%)
Frame = +2
Query: 146 QIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELL 325
+I VT + E G+ L+ V++ + + +A L+ + + + ++ E+L
Sbjct: 3 RILVTEP-IAEEGLARLRAAAHVDV---RTDLDKAGLIAILPEYDALIVRSATRVTAEVL 58
Query: 326 DAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPE 505
AAG L+VV G D+ID+ ++G+ + P +R +P+
Sbjct: 59 -AAGTRLRVVGRAGTGVDNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQ 117
Query: 506 AIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
A H + G W G + T+G+VG GRIG VARR + + Y
Sbjct: 118 A-HSSVVAG--KWERNRFMGFEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDPVVST 174
Query: 686 PEEKETGAVKVSFDELLTQSDFV 754
+ GA +E+L Q+D V
Sbjct: 175 ERAAQLGATLAPLEEVLAQADIV 197
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 64.9 bits (151), Expect = 2e-09
Identities = 47/145 (32%), Positives = 70/145 (48%), Gaps = 5/145 (3%)
Frame = +2
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P+LKV++ VG +IDVA +RG+ + TP +RR+
Sbjct: 90 AACPTLKVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWM 149
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIY---FNRS 679
E + G W S A G L+G T+G++GFG++GQ VAR A + + + F+ +
Sbjct: 150 DAELRAGRW-SRA---QDGLELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDPAFDPA 205
Query: 680 HRPEEKETGAVKV--SFDELLTQSD 748
P V++ S DELL SD
Sbjct: 206 CAPGPGAVAGVRMLGSVDELLPLSD 230
>UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
glyoxylate reductase - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 315
Score = 64.5 bits (150), Expect = 3e-09
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 1/148 (0%)
Frame = +2
Query: 245 RAELLKEVAGVNG-IYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRI 421
R LL++ ++ + C+ ID LL P+LK+ A S G+D +D+ +RG+++
Sbjct: 36 RDALLQQAGPISSALVCNGHVTIDEALLSKL-PALKLAACSSAGYDQMDLEAMTRRGIKL 94
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
T +V RR+PE ++G W +T +G GIVG
Sbjct: 95 TNTSEVLCDDVADMALLLMLAARRRLPEGDRYVRSGDWGQKGMMPLT-TSTSGKKAGIVG 153
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHR 685
GRIG A+A+R +A I Y+ R+ +
Sbjct: 154 LGRIGMAIAKRCEAVGL-TIGYYGRTKK 180
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 64.5 bits (150), Expect = 3e-09
Identities = 46/152 (30%), Positives = 73/152 (48%), Gaps = 2/152 (1%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
KID +++ A+ LK +A VG+D+IDV +RG+ +
Sbjct: 66 KIDDQVIGAS-QKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFA 124
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
+R +P KTG W A T G L G ++G++GFG IG+ + V+ + E I
Sbjct: 125 VAREIPHLDARIKTGHWDK-ATT--KGAQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRI 181
Query: 665 YFNRSHRPEEKE-TGAVKV-SFDELLTQSDFV 754
+ + P + E +GA + S DE+LT SD +
Sbjct: 182 F--DPYMPADAEISGAERAGSLDEILTASDVI 211
>UniRef50_A1W7E2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=11; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Acidovorax sp. (strain
JS42)
Length = 328
Score = 64.5 bits (150), Expect = 3e-09
Identities = 45/143 (31%), Positives = 64/143 (44%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L+ V++ VG D +D A ++ G R+GYTP V +R + A
Sbjct: 69 PRLRFVSSFGVGFDALDQAALQECGARVGYTPGVLDDCVADMAFALLLDAARSLSAADRF 128
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
+ G W + +G +GI G GRIG AVARR F+ + + Y NR RP E
Sbjct: 129 VRRGDWS--RQRFGVHTRASGKRLGIFGMGRIGAAVARRAAGFDMQ-VGYHNR--RPVEG 183
Query: 698 ETGAVKVSFDELLTQSDFVICCA 766
S EL +DF++ A
Sbjct: 184 SPHQYLPSLMELARWADFLVITA 206
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 63.7 bits (148), Expect = 5e-09
Identities = 37/142 (26%), Positives = 65/142 (45%)
Frame = +2
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
A P LKV+A VG+D++D+ + G+R+ TP V +RR+
Sbjct: 66 ATSPMLKVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTV 125
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
+ GGW A G L G ++G++G+G G+A+A A ++ + +H
Sbjct: 126 LAGVDDGGWPREA-----GTELRGKSLGVIGYGPSGKAIAALGVALGMRVLV--STAHPD 178
Query: 689 EEKETGAVKVSFDELLTQSDFV 754
E+ +G FD + +D++
Sbjct: 179 SEQSSGIEFADFDTTIKAADYL 200
>UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase and
related dehydrogenases; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1052: Lactate dehydrogenase
and related dehydrogenases - Magnetospirillum
magnetotacticum MS-1
Length = 167
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/140 (25%), Positives = 64/140 (45%)
Frame = +2
Query: 122 NMSAKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLT 301
NMS+ R + V +P++ +++ D L + +P+ + L + + + ++T
Sbjct: 23 NMSSLKRKPLVVVTRRLPDAVETRMRELFDTRLNHDDAPLSQEALAAAIREADVLVPTVT 82
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
D+I+ LL AGP+L+++A G DHIDV +RG+ + TP V
Sbjct: 83 DEINAGLLAQAGPNLRLIANFGNGVDHIDVGAALERGITVTNTPGVLTEDTADMTMALIL 142
Query: 482 XXSRRVPEAIHEAKTGGWVS 541
+RR+ E W +
Sbjct: 143 AVARRIAEGARIIPEDEWTN 162
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 63.7 bits (148), Expect = 5e-09
Identities = 49/205 (23%), Positives = 86/205 (41%)
Frame = +2
Query: 140 RYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTE 319
R +I VT + + +S V LL D D++++ P P + A + + T+
Sbjct: 11 RRRILVTHTQIAQSAVDLLNDH-DIDVFFSPPYDPSDVVAARAAELRIDAMMVRQGRITD 69
Query: 320 LLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRV 499
+ A P LKV+ VG D+ID+A + RG+ + + + +
Sbjct: 70 EVIGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEI 129
Query: 500 PEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
K G W PT++ G GA +G+VG+G IG+ AR +A E +++ +
Sbjct: 130 QPLNAAVKGGAWPK--PTFI-GKDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPYA 186
Query: 680 HRPEEKETGAVKVSFDELLTQSDFV 754
E + A + +L D +
Sbjct: 187 PEAAEADGFAAAADLEAMLPALDIL 211
>UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; marine gamma
proteobacterium HTCC2143|Rep: D-isomer specific
2-hydroxyacid dehydrogenase family protein - marine
gamma proteobacterium HTCC2143
Length = 312
Score = 63.7 bits (148), Expect = 5e-09
Identities = 39/142 (27%), Positives = 64/142 (45%)
Frame = +2
Query: 221 WNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAEC 400
W QPS A + + + V + + +K+D +L A P+L+++A+IS G +ID+ EC
Sbjct: 27 WIQPSENIDATIERHGSDVEILLSASIEKLDKAML-ARFPNLRMIASISAGFSNIDLEEC 85
Query: 401 KKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAG 580
+ RG+ + P + R+P++ W+ P L
Sbjct: 86 RSRGIAVTNAPGMNSGDVADLAVTLLTSLLLRIPQSQSYIMNDQWIGKTPP--LRHSLRN 143
Query: 581 ATVGIVGFGRIGQAVARRVKAF 646
VGIVG G IG+ V R+ F
Sbjct: 144 MPVGIVGLGSIGRDVVTRLTPF 165
>UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 527
Score = 63.7 bits (148), Expect = 5e-09
Identities = 49/164 (29%), Positives = 70/164 (42%), Gaps = 2/164 (1%)
Frame = +2
Query: 269 AGVNGIYCSLTDKIDTELLDAAGPS-LKVVATISVGHDHIDVAECKKRGVRIGYTPDVXX 445
AG I + D++D+ ++ A S K+VA G+D +D+ G+ + P
Sbjct: 43 AGFPAISAFVNDQLDSTIMRALAESGTKLVALRCSGYDRVDIKAATANGITVTRVPAYSP 102
Query: 446 XXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAV 625
RR P A + G ++ T G G+ G TVGIVG GRIG V
Sbjct: 103 EAIVEYTVGMLIALDRRTPHAWQRVRAG---NFDLTGFVGHGIHGKTVGIVGTGRIGAGV 159
Query: 626 ARRVK-AFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
AR K F E ++ + ++ G V F ELL SD V
Sbjct: 160 ARVFKNGFQCE-VLANDLYPNATLEQHGVRYVEFKELLKSSDIV 202
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 63.7 bits (148), Expect = 5e-09
Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 2/170 (1%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
ELL+ + + K+ LL AA LKVVA VG D++DV E K G+ + +
Sbjct: 41 ELLQIIPEYEALVVRSETKVTGNLLRAA-KQLKVVARAGVGVDNVDVEEATKLGIVVVNS 99
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
P +R +PEA K+G W + G + G T+ I+G G+
Sbjct: 100 PSGNIGAAAEHTIALLIAMARNIPEACSSLKSG---KWERSKFVGVEVKGKTLSIIGLGK 156
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV--SFDELLTQSDFV 754
+G VAR K + + P + +V + S ELL +DF+
Sbjct: 157 VGLTVARLAKGLGM-NVNALDPYASPAVAVSASVTLVSSLSELLPTADFL 205
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 63.3 bits (147), Expect = 6e-09
Identities = 44/168 (26%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Frame = +2
Query: 260 KEVAGVNGIYCSLTDKIDTEL---LDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
+E+ + G Y +L + T++ + AG L+V+ VG D+ID+ G+ +
Sbjct: 33 EELISIIGEYDALLVRSQTQVTADIINAGKKLQVIGRAGVGVDNIDLKTATGNGIIVVNA 92
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
P +R +P A K+G W G L G T+GIVG G
Sbjct: 93 PTGNTISATEHTLALMLAMARHIPRANASLKSG---QWKRNEFVGSELKGKTLGIVGLGN 149
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
IG +A+R A I Y K+ + F++LL ++DF+
Sbjct: 150 IGSEIAKRALALEMRVIGYDPFISMERAKKLQVELLPFEDLLKRADFI 197
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 63.3 bits (147), Expect = 6e-09
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 2/152 (1%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
K+ E+L+ A LK+VA +G D+IDV K +G+ + TP
Sbjct: 53 KVTKEILEHAD-KLKIVARAGMGLDNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLD 111
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
R + K W + G L+ T GI+GFG +G+ +A+ +K F T ++
Sbjct: 112 IYRHITRGTIGLKNE---QWEKKQLEGFELSQKTFGIIGFGYVGKNLAQLLKGFQTNTLV 168
Query: 665 Y--FNRSHRPEEKETGAVKVSFDELLTQSDFV 754
Y F S E+K +VS +ELL SD +
Sbjct: 169 YDVFEIS-AEEQKNYNVRQVSLEELLQNSDII 199
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 62.9 bits (146), Expect = 8e-09
Identities = 50/202 (24%), Positives = 85/202 (42%), Gaps = 1/202 (0%)
Frame = +2
Query: 152 YVTRSD-MPESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLD 328
+V SD + E G++ L++ ++ + P EL ++ + I ++ L++
Sbjct: 4 HVLISDPLSEEGLKPLQEAENIEVVINPG-WNEQELSDQIDSFDAILVRSQTQVTRALIE 62
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
A +LK++ VG D+ID+ + GV + P+ SR +P+A
Sbjct: 63 KAS-NLKIIGRAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQA 121
Query: 509 IHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRP 688
H K W G L T+GIVG GRIG VA R K I Y
Sbjct: 122 YHALKQK---QWDRKRFVGVELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEE 178
Query: 689 EEKETGAVKVSFDELLTQSDFV 754
+ ++ G + +++L DF+
Sbjct: 179 KAEQMGVQYGTLEDVLRAGDFI 200
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 62.9 bits (146), Expect = 8e-09
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P LKV++ VG D +D+A + + + TP V +R
Sbjct: 69 PDLKVISRYGVGFDAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRA 128
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
++G W +T P + G+T+GIVG GRIGQAVA R ++ ++ E
Sbjct: 129 VRSGEW----ERELT-PRVWGSTIGIVGLGRIGQAVATRAIGMGM-HVLAYDPFPNEEFA 182
Query: 698 ETGAVK-VSFDELLTQSDFV 754
+T +K +S +ELL QSD+V
Sbjct: 183 KTHQIKLLSLEELLKQSDYV 202
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 62.9 bits (146), Expect = 8e-09
Identities = 42/152 (27%), Positives = 66/152 (43%)
Frame = +2
Query: 317 ELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRR 496
E+++A+ P LK++A VG D++D+ + V + TP +RR
Sbjct: 55 EMIEAS-PRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRR 113
Query: 497 VPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNR 676
+ A + G W + G L+G T+GIVGFG IG+ VA F +
Sbjct: 114 IIPAANRVLAGTWAEGRGD-LVGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDPI 172
Query: 677 SHRPEEKETGAVKVSFDELLTQSDFVICCAXL 772
+ + + GAV V D L +D + A L
Sbjct: 173 ATAADAEAAGAVLVELDTLYDGADIITLHAPL 204
>UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=10; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 334
Score = 62.5 bits (145), Expect = 1e-08
Identities = 39/148 (26%), Positives = 65/148 (43%)
Frame = +2
Query: 242 PRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRI 421
P A L + + G+ + + L++ P+L++VA +G D +D+ + RG+ +
Sbjct: 56 PDALLDRVATRIRGVVTGGANGLSAALMNRL-PALEIVAISGIGTDAVDLDRARARGIHV 114
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
TPDV R + + G W A T + G +GIVG
Sbjct: 115 TTTPDVLTDDVADMAMGLILMTLRDLGAGERIVRAGRWGKTAQPLATQ--VTGKRLGIVG 172
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHR 685
GR+G+A+A+R +AF + R HR
Sbjct: 173 LGRVGRAIAQRAQAFRMPVSYFGPREHR 200
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 62.5 bits (145), Expect = 1e-08
Identities = 40/150 (26%), Positives = 66/150 (44%)
Frame = +2
Query: 305 KIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXX 484
++ E+L A P L+++AT S G+DHID+ C+ G+ + PD
Sbjct: 53 RLTAEVL-AQFPRLRLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLA 111
Query: 485 XSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERII 664
SR + + G ++ + G L G T+G++G GRIG+ V K F + +
Sbjct: 112 VSRHIVTGAERTRRG---DFSQHGLRGFELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVA 168
Query: 665 YFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
Y + G + LL+Q+D V
Sbjct: 169 YDLFPDAAVAEHLGYEYLDLHVLLSQADVV 198
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 62.1 bits (144), Expect = 1e-08
Identities = 60/212 (28%), Positives = 87/212 (41%), Gaps = 4/212 (1%)
Frame = +2
Query: 131 AKGRYQIYVTRSDMPESGVQLLKDQCDVNLWNQPSPVPRAE---LLKEVAGVNGIYCSLT 301
A + +I+VT++ + + LL + D+ L + + + LLK A V+G+ T
Sbjct: 2 ATNKKKIFVTQT-LSQGARTLLTQRDDIELVEFANLISAKDFQALLKSHAPVHGVALGAT 60
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
+TEL A +KVV I VG+D +DV +R V +
Sbjct: 61 AFGETEL--EASKDMKVVTRIGVGYDAVDVPALSRRKVPLMVAGSANSPSVAEQALFMML 118
Query: 482 XXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERI 661
++R E K G W M L G TV I+GFGRIG A+R A
Sbjct: 119 TLAKRAQEMHSCVKDGKWAD--RLGMLPFDLYGKTVLIIGFGRIGTRTAKRCLAMEMRVQ 176
Query: 662 IYFNRSHRPEEKETGAVKVS-FDELLTQSDFV 754
+Y E K G V+ D L +DFV
Sbjct: 177 VYDPYKPAAEIKAAGYEPVADLDAALPHADFV 208
>UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermofilum pendens Hrk
5|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermofilum pendens (strain Hrk 5)
Length = 320
Score = 62.1 bits (144), Expect = 1e-08
Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 1/167 (0%)
Frame = +2
Query: 260 KEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDV 439
K AG+ ++ + + AAG LK V + G D++D+ +RGV++ +
Sbjct: 34 KGFAGIEEADVAIAFILPRDAAQAAG-RLKFVQVPAAGADNLDLEYLFERGVKVATSKGC 92
Query: 440 XXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQ 619
++RV E E K G W S+ L G+TV IVG+G IG+
Sbjct: 93 NARAVAEHAFALILALAKRVVEQDGEVKRGLWRSFTEENFLAD-LDGSTVTIVGYGNIGR 151
Query: 620 AVARRVKAFNTERIIYFNRSHRPEEKETGAVKVS-FDELLTQSDFVI 757
VAR KAFN R++ ++ + V E L+Q+DFV+
Sbjct: 152 EVARIAKAFNM-RVLAVKKNPEKDSLADEVYPVERLAEALSQADFVV 197
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 61.7 bits (143), Expect = 2e-08
Identities = 43/171 (25%), Positives = 71/171 (41%)
Frame = +2
Query: 242 PRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRI 421
P A+L+K + + ++KI E++D P LK++ G + ID+ +K + +
Sbjct: 32 PLADLVKANSDAE-VLIVRSEKITPEIIDLL-PQLKLIVRAGAGFNTIDIKYARKHDIDV 89
Query: 422 GYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVG 601
TP SR + A + G W + G L G TVGI+G
Sbjct: 90 MNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKG---DWEKSKFMGRELTGKTVGILG 146
Query: 602 FGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKVSFDELLTQSDFV 754
G IGQ + +R+ F + + Y + G + D + +SDFV
Sbjct: 147 LGHIGQLLVKRLAGFEMKVLGYDPMLSPALADKLGVELTTVDRIFAESDFV 197
>UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibacter
mediatlanticus TB-2|Rep: D-lactate dehydrogenase -
Caminibacter mediatlanticus TB-2
Length = 310
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
E+L++ + I T KID ++L+ P+LK + T S G DH+D+ E KRG+
Sbjct: 36 EVLEKPMNFDVISVFYTSKIDKDVLNKL-PNLKYIQTRSTGVDHLDLVEIYKRGIIASNV 94
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
R++ AI K W + G + G T+GI+G G
Sbjct: 95 VGYAGPCVGEFAYGLLLEAIRKLYVAIVRLK---WGCREYEDLKGIEIEGKTIGILGLGT 151
Query: 611 IGQAVARRVKAFNTERIIYFNRSHRPE-EKETGAVKVSFDELLTQSDFV 754
IG +A+ K FN + I NRS++ E + + D +L +SDF+
Sbjct: 152 IGTQMAKIAKGFNA-KTIGLNRSYKKEFDDLVDEFTQNLDYVLEKSDFL 199
>UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii
AK1|Rep: Dehydrogenase - Vibrio shilonii AK1
Length = 337
Score = 61.7 bits (143), Expect = 2e-08
Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 4/214 (1%)
Frame = +2
Query: 125 MSAKGRYQIYVTRSDMPESGVQ---LLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCS 295
M+A+ ++++YV+ D P+ ++ L +V + + EL K+ + Y
Sbjct: 1 MTAETKFKVYVSDYDYPDLEIERSVLEPIGAEVIGLKCKTGIGLGELAKDADAILQQYAK 60
Query: 296 LTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXX 475
+ + E LD + K++ +G D +DV C G+++ PD
Sbjct: 61 IP-RTTIEQLD----NCKIICRYGIGVDILDVEACYDHGIKVSNVPDYCIDEVADHSISL 115
Query: 476 XXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTE 655
RR+P G W W + +T G++GFGRI Q +A+++ A
Sbjct: 116 GLTLFRRIPAYNKFTHEGQW-HWDIDGLVPKRFRSSTWGLIGFGRIAQNIAKKMTALGF- 173
Query: 656 RIIYFNRSHRPEEKET-GAVKVSFDELLTQSDFV 754
++I F+ T G KV D L++ SD V
Sbjct: 174 KVISFDPYVSGSYMNTFGVEKVDLDTLISTSDVV 207
>UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 413
Score = 61.7 bits (143), Expect = 2e-08
Identities = 43/159 (27%), Positives = 69/159 (43%), Gaps = 6/159 (3%)
Frame = +2
Query: 296 LTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXX 475
+T + D EL+ +L+ + G+D +DV +G++ P
Sbjct: 132 VTGRFDAELVSQLPSTLRYIVHNGAGYDQLDVQALSDKGIQASNVPTAVDDATSDVALYL 191
Query: 476 XXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTE 655
RR P A + G + S A +++ G T+GIVG G IG+A A +
Sbjct: 192 LLGALRRFPRAKAQMNAGKFNS-AFSFLDARDPRGKTLGIVGAGGIGRAFAHKASHALGV 250
Query: 656 RIIYFNRSHRPEEKETGAVK------VSFDELLTQSDFV 754
++IY NR+ + E+ A K + +ELL QSD V
Sbjct: 251 KVIYHNRNQLSSDVESQAAKGGMKYAKTLEELLQQSDIV 289
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 61.3 bits (142), Expect = 3e-08
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 2/198 (1%)
Frame = +2
Query: 185 VQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATI 364
++ LK V+ + P + L +++ G + I S+ D E + +L ++A
Sbjct: 43 IERLKALGQVDRFELPHDMRGKALAEKLMGYSIIIASVKPYYDREFFEYKDETL-LIARH 101
Query: 365 SVGHDHIDVAECKKRGVRIGYTPD-VXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVS 541
+G+D ID+ K+G + V R+V EA + K G W
Sbjct: 102 GIGYDAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKWHE 161
Query: 542 WAPTWMTGPGLAGATVGIVGFGRIGQAVARRVK-AFNTERIIYFNRSHRPEEKETGAVKV 718
A G + G T GI+G G IG VA +K F E I Y + E + A V
Sbjct: 162 RAN--FIGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDPNLSKEEIIKREARPV 219
Query: 719 SFDELLTQSDFVICCAXL 772
S +ELL SD + A L
Sbjct: 220 SLEELLRSSDIISLNASL 237
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 61.3 bits (142), Expect = 3e-08
Identities = 41/147 (27%), Positives = 64/147 (43%)
Frame = +2
Query: 314 TELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSR 493
T + A P L V++ VG++ +DV + G + R
Sbjct: 67 TRAVFEALPDLAVISRRGVGYEKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISIGR 126
Query: 494 RVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFN 673
R EA K G W + G L VGIVGFGRIG+++ARR+ F E ++
Sbjct: 127 RFQEAQSAMKAGKW-----NILVGTELYRRKVGIVGFGRIGRSLARRLSGFEAEILVCAP 181
Query: 674 RSHRPEEKETGAVKVSFDELLTQSDFV 754
R + + G V+F+ LL ++D++
Sbjct: 182 RLASEDIETFGLRHVAFETLLKEADYI 208
>UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocystis
pacifica SIR-1|Rep: Putative dehydrogenase -
Plesiocystis pacifica SIR-1
Length = 337
Score = 61.3 bits (142), Expect = 3e-08
Identities = 45/164 (27%), Positives = 70/164 (42%), Gaps = 1/164 (0%)
Frame = +2
Query: 248 AELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGY 427
A +L +A + I ++D + L A + + SVG++H+D+ + RG+ +
Sbjct: 42 AAVLPALADADAIIVWSRFELDADAL-ATLERCRGIVCASVGYEHVDLEAARARGIPVCN 100
Query: 428 TPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFG 607
PD +R++ + G W W M L G ++G+VGFG
Sbjct: 101 VPDYGTEEVADHATALLLGLARKLAVLDRSVREGQW-DWQLGGMP-TRLRGQSLGVVGFG 158
Query: 608 RIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV-SFDELL 736
RIG A RR +AF E + EK G + S DELL
Sbjct: 159 RIGAAFTRRAQAFGLEPAFFDPHVPSGVEKVLGVRRCESLDELL 202
>UniRef50_A5V984 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Sphingomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 309
Score = 61.3 bits (142), Expect = 3e-08
Identities = 44/148 (29%), Positives = 68/148 (45%)
Frame = +2
Query: 212 VNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDV 391
+ LW + P PR +A V+ + + ++ EL++ P L ++A +VG+D +DV
Sbjct: 28 IALWEEKDP-PR------LAEVSALIMAGEFRLPPELVERM-PKLGLIACFTVGYDGVDV 79
Query: 392 AECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPG 571
A + RG+++ + D RR+ + G W A +TG
Sbjct: 80 AAVRARGIQVCHAHDANNEDVADHAIGMILAERRRIFSGDRMLRAGEWKPGAKL-ITG-S 137
Query: 572 LAGATVGIVGFGRIGQAVARRVKAFNTE 655
L GA +GIVG G IG AVARR E
Sbjct: 138 LDGARIGIVGLGSIGAAVARRADVMRME 165
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 61.3 bits (142), Expect = 3e-08
Identities = 35/139 (25%), Positives = 61/139 (43%)
Frame = +2
Query: 251 ELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYT 430
ELL + +GI ++ + + AA LKV+ +G D++D ++G+ + T
Sbjct: 35 ELLACIDQYDGIAIRSATRLPAQAI-AAASRLKVIGRAGIGVDNVDTPAASQKGIIVMNT 93
Query: 431 PDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGATVGIVGFGR 610
P +R +P A K G W + G LAG T G++G G
Sbjct: 94 PFGNAITTAELGVTLAMAAARHIPAATASTKAG---KWEKSRFMGRELAGKTAGVIGLGN 150
Query: 611 IGQAVARRVKAFNTERIIY 667
+G+ VA+R+ + + + Y
Sbjct: 151 VGRLVAQRLAGLDMKVVAY 169
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 61.3 bits (142), Expect = 3e-08
Identities = 41/177 (23%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = +2
Query: 230 PSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVATISVGHDH-IDVAECKK 406
P + E+++ +AGV+ + + +++ +A +LKV++ VG+ + +DV KK
Sbjct: 41 PGVLKEDEIIEALAGVDAYIPGGEEVVTEKIIASAKNTLKVISFNGVGYGYYVDVPAAKK 100
Query: 407 RGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWVSWAPTWMTGPGLAGAT 586
+ + P +++P E K+G W + ++ T
Sbjct: 101 HNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHKYI-----SQDVSDKT 155
Query: 587 VGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPE-EKETGAVKVSFDELLTQSDFV 754
+GIVG G IG+ VA+++ +I+Y++R+ + E+E A V +L SD +
Sbjct: 156 IGIVGMGSIGRLVAKKMYYGFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSDVI 212
>UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=7;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Silicibacter pomeroyi
Length = 313
Score = 60.9 bits (141), Expect = 3e-08
Identities = 37/116 (31%), Positives = 53/116 (45%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P L V+A VG+D IDVA RG+ + TP V RR+ +
Sbjct: 64 PGLGVIANFGVGYDAIDVAAATARGITVTNTPGVLNDDVADLAVTMLLMQCRRMEQGGAW 123
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHR 685
+ G W + + +G G+VG GRIG+ +A R+ AF + I YF RS +
Sbjct: 124 VREGHWET--ANFPLNRKASGGVAGVVGLGRIGREIADRLAAFKMD-IHYFARSEK 176
>UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=13;
Staphylococcus|Rep: NAD-dependent formate dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 389
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/145 (31%), Positives = 62/145 (42%)
Frame = +2
Query: 338 PSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHE 517
P+LK+V T VG DH+D+ + + + R E +
Sbjct: 125 PNLKLVITAGVGSDHVDLQAASEHNIGVVEVTGSNTISVAEHAVMDLLILLRNYEEGHRQ 184
Query: 518 AKTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEK 697
AK G W + + L T+GI GFGRIGQ VA R+ FN Y + + E
Sbjct: 185 AKDGEW-NLSKVGNHVHELQIKTIGIFGFGRIGQLVAERLAPFNVTIQHYDPINQKDNEH 243
Query: 698 ETGAVKVSFDELLTQSDFVICCAXL 772
T V+FDEL++ SD V A L
Sbjct: 244 ST---FVNFDELVSTSDAVTIHAPL 265
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 60.9 bits (141), Expect = 3e-08
Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
Frame = +2
Query: 329 AAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEA 508
AA P+L++VA+ G+++I+ + RGVR+ + PD SR +
Sbjct: 65 AALPALELVASFGAGYENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAML 124
Query: 509 IHEAKTGGWVSW-APTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
K G W + AP PG+ G T+GIVG G IGQ +A +A R+ Y RS
Sbjct: 125 DRGLKAGQWDALRAPR----PGVRGKTLGIVGLGNIGQRLAALAEAVGM-RVAYLRRS 177
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/192 (23%), Positives = 84/192 (43%)
Frame = +2
Query: 179 SGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAAGPSLKVVA 358
+G++L + + QP + LLK + + + + EL+ AA LK++A
Sbjct: 12 AGLKLFDEAEGITADYQPG-ITHDNLLKIINNYDALIVRGGTTVSEELIFAA-KRLKIIA 69
Query: 359 TISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKTGGWV 538
+G ++I + +G+ + TP +R +P+A HE+ + G
Sbjct: 70 RAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQA-HESMSQG-- 126
Query: 539 SWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETGAVKV 718
W T G + T+G++G G+IG+ V + + +Y GA KV
Sbjct: 127 KWQSTEFLGSDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLYDPYLSEEVITRLGASKV 186
Query: 719 SFDELLTQSDFV 754
S ++LL+ +DF+
Sbjct: 187 SLEDLLSTADFI 198
>UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pseudomonas putida
W619|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas putida W619
Length = 312
Score = 60.9 bits (141), Expect = 3e-08
Identities = 38/113 (33%), Positives = 55/113 (48%)
Frame = +2
Query: 341 SLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEA 520
+L ++A VG D ID+ + K RG+R+ T D+ R+V A
Sbjct: 74 NLSLIAVNGVGVDGIDLDQVKARGIRVETTIDILTDAVADHAVALLLSLLRQVCVADRFV 133
Query: 521 KTGGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRS 679
+ G W A + G L G VGI+G GRIGQA+A R+ F ++ Y NR+
Sbjct: 134 RAGMWREGAFPSL-GTTLRGLRVGIIGLGRIGQAIASRLLPFGV-KLAYHNRN 184
>UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:
Predicted protein - Ajellomyces capsulatus NAm1
Length = 316
Score = 60.9 bits (141), Expect = 3e-08
Identities = 47/155 (30%), Positives = 68/155 (43%), Gaps = 4/155 (2%)
Frame = +2
Query: 302 DKIDTELLDAAGPSLKVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXX 481
+ D ELL P K++A+ S G++ DV + + T +
Sbjct: 73 EPFDEELLGPLAPHCKIIASGSAGYNEFDVDWMTRSKIWFCNTRNAVSEATADMSMFLIL 132
Query: 482 XXSRRVPEAIHEAKTGGWVSW-APTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTER 658
+ A A+ G W PT P G T+GIVG G IG+ +AR+ AFN +
Sbjct: 133 AVLKNATVAERSAREGRWKDGLVPT--KDP--RGLTLGIVGMGSIGKHLARKALAFNL-K 187
Query: 659 IIYFNRSHRPEEKE---TGAVKVSFDELLTQSDFV 754
I Y+NR+ P + E + S DELL+ SD V
Sbjct: 188 IKYYNRTQLPADVEAQYSATYCASLDELLSVSDIV 222
>UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Halorubrum
lacusprofundi ATCC 49239
Length = 324
Score = 60.9 bits (141), Expect = 3e-08
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 2/196 (1%)
Frame = +2
Query: 173 PESGVQLLKDQCDVNLWNQPSPVPRAELLKEVAGVNGIYCSLTDKIDTELLDAA--GPSL 346
PE+ ++L + D + + + + E L E A G +TD IDT + D A L
Sbjct: 14 PETYREVLDEAVDEPVEIEVAQLGSTERLIEAAA--GADAVVTD-IDTPVTDEALGRLDL 70
Query: 347 KVVATISVGHDHIDVAECKKRGVRIGYTPDVXXXXXXXXXXXXXXXXSRRVPEAIHEAKT 526
+ V +VG D++DV +RGV + PD R +
Sbjct: 71 RAVVRAAVGVDNVDVGAAAERGVTVTRAPDYCTDEVAIHSVSLLLACLRSLKAYDDHVVD 130
Query: 527 GGWVSWAPTWMTGPGLAGATVGIVGFGRIGQAVARRVKAFNTERIIYFNRSHRPEEKETG 706
GW SW ++ +TVG V FG I + A ++ F+ + + Y E E G
Sbjct: 131 DGW-SWE-VGRPIRRVSASTVGFVSFGPIARRAAEQIAGFDADLVAYDPFVEADEMAEYG 188
Query: 707 AVKVSFDELLTQSDFV 754
K FDEL ++D V
Sbjct: 189 VEKADFDELFDRADHV 204
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 767,226,330
Number of Sequences: 1657284
Number of extensions: 15305557
Number of successful extensions: 49915
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 46372
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 49396
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 64615845515
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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