Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_F_E20
(835 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 340 5e-93
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 340 5e-93
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 340 5e-93
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 340 5e-93
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 340 5e-93
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 340 5e-93
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 340 5e-93
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 340 5e-93
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 340 5e-93
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 340 5e-93
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 312 8e-85
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 312 8e-85
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 312 8e-85
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 312 8e-85
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 312 8e-85
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 312 8e-85
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 312 8e-85
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 284 3e-76
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 247 3e-65
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 102 1e-21
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 55 3e-07
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 40 0.015
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 340 bits (835), Expect = 5e-93
Identities = 158/220 (71%), Positives = 184/220 (83%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAG 750
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAG
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 243 SPFEHCHVVTTTTHKTLRG--CR 263
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 87 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 146
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 147 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 206
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 207 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 240
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 245 SPFKHADIVTTTTHKTLRG 263
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 78 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 137
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 138 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 197
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 198 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 231
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 236 SPFKHADIVTTTTHKTLRG 254
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 266 SPFKHADIVTTTTHKTLRG 284
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 266 SPFKHADIVTTTTHKTLRG 284
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 266 SPFKHADIVTTTTHKTLRG 284
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 266 SPFKHADIVTTTTHKTLRG 284
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 312 bits (767), Expect = 8e-85
Identities = 141/214 (65%), Positives = 178/214 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 266 SPFKHADIVTTTTHKTLRG 284
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 284 bits (696), Expect = 3e-76
Identities = 134/214 (62%), Positives = 168/214 (78%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++ LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSA 217
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 218 YARLIDYARMREVCDEVKAHLLADMAHISGLVAA 251
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 256 SPFKHADIVTTTTHKTLRG 274
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 247 bits (605), Expect = 3e-65
Identities = 111/159 (69%), Positives = 135/159 (84%)
Frame = +1
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIM
Sbjct: 79 QRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 138
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLII
Sbjct: 139 GLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLII 198
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAA 747
AG S Y+R +DY R RE+ D A+L+ADMAH+SGLVAA
Sbjct: 199 AGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA 237
Score = 37.9 bits (84), Expect = 0.045
Identities = 15/19 (78%), Positives = 18/19 (94%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRG 815
+PF++ DIVTTTTHKTLRG
Sbjct: 242 SPFKHADIVTTTTHKTLRG 260
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 102 bits (245), Expect = 1e-21
Identities = 47/66 (71%), Positives = 56/66 (84%)
Frame = +1
Query: 553 VDPKSGLIDYDKLAETAKLFKPRLIIAGMSCYSRCLDYKRFREIADANGAYLMADMAHVS 732
V+P +G I+YD+L E A+LF P+LIIAG SCYSR L+Y R R+IAD NGAYLMADMAH+S
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS 60
Query: 733 GLVAAG 750
GLVAAG
Sbjct: 61 GLVAAG 66
Score = 40.3 bits (90), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 759 APFEYCDIVTTTTHKTLRGPSCR 827
+PFE+C +VTTTTHKTLRG CR
Sbjct: 70 SPFEHCHVVTTTTHKTLRG--CR 90
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 55.2 bits (127), Expect = 3e-07
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +1
Query: 274 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQP 384
RYYGG E+IDE+E L Q R+L+AY+L + WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 39.5 bits (88), Expect = 0.015
Identities = 16/30 (53%), Positives = 26/30 (86%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASE 195
+L ++DPE+++++ +EKDRQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 127,339,324
Number of Sequences: 237096
Number of extensions: 2780316
Number of successful extensions: 9167
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 8876
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9166
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10482413384
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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