Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P29_F_B12
(832 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 313 4e-84
UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 231 2e-59
UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 224 2e-57
UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 207 3e-52
UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 206 5e-52
UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 200 3e-50
UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 187 3e-46
UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 180 3e-44
UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 152 9e-36
UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 145 1e-33
UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 145 1e-33
UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 137 4e-31
UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 135 1e-30
UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 129 7e-29
UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 123 5e-27
UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 123 5e-27
UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 123 6e-27
UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 116 7e-25
UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 116 1e-24
UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 115 1e-24
UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 115 2e-24
UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 113 4e-24
UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 111 2e-23
UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 108 1e-22
UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 108 2e-22
UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 107 4e-22
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 106 6e-22
UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 106 8e-22
UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 106 8e-22
UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 104 2e-21
UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 104 2e-21
UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 101 3e-20
UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 99 2e-19
UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 64 3e-19
UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 97 4e-19
UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 97 4e-19
UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 97 5e-19
UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 97 6e-19
UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 96 8e-19
UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 94 4e-18
UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 94 4e-18
UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 93 6e-18
UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 93 6e-18
UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 93 8e-18
UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 93 1e-17
UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 92 1e-17
UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 92 2e-17
UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 92 2e-17
UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 92 2e-17
UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 91 2e-17
UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 91 4e-17
UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 91 4e-17
UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 90 7e-17
UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 89 2e-16
UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 88 3e-16
UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 88 3e-16
UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 87 5e-16
UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 87 5e-16
UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 87 7e-16
UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 87 7e-16
UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 87 7e-16
UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 86 9e-16
UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 86 9e-16
UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 85 2e-15
UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 85 2e-15
UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 85 2e-15
UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 85 2e-15
UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 85 3e-15
UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15
UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 83 1e-14
UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 83 1e-14
UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 82 1e-14
UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 82 1e-14
UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 82 2e-14
UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 79 1e-13
UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 77 5e-13
UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 76 1e-12
UniRef50_Q9BZ93 Cluster: Prosomal P27K protein; n=6; Eutheria|Re... 76 1e-12
UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 76 1e-12
UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 76 1e-12
UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 75 2e-12
UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 75 2e-12
UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 75 2e-12
UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 74 4e-12
UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 74 5e-12
UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 73 7e-12
UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1... 73 9e-12
UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 72 2e-11
UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 71 3e-11
UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 71 5e-11
UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 68 3e-10
UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 68 3e-10
UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 66 1e-09
UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 64 4e-09
UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 63 7e-09
UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 63 9e-09
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 62 1e-08
UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 62 2e-08
UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 62 2e-08
UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 61 3e-08
UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1; ... 59 1e-07
UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 58 2e-07
UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 58 2e-07
UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 56 8e-07
UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 56 1e-06
UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 56 1e-06
UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1; ... 54 4e-06
UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 54 6e-06
UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 51 4e-05
UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 50 5e-05
UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 49 1e-04
UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 49 1e-04
UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 45 0.003
UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2; Olig... 44 0.004
UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 44 0.005
UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1; Spra... 43 0.011
UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 43 0.011
UniRef50_Q9U794 Cluster: Proteasome subunit beta type-1; n=7; Tr... 43 0.011
UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 41 0.033
UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 41 0.033
UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar... 41 0.044
UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 39 0.13
UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 38 0.23
UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 36 0.94
UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giar... 36 1.2
UniRef50_Q980L4 Cluster: Proteasome subunit; n=4; Sulfolobaceae|... 36 1.2
UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9; ... 36 1.2
UniRef50_UPI0000DB72B7 Cluster: PREDICTED: similar to CG3558-PA,... 35 2.9
UniRef50_Q0FG88 Cluster: Putative uncharacterized protein; n=1; ... 35 2.9
UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole gen... 35 2.9
UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella ch... 34 3.8
UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;... 34 5.0
UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1; Tric... 33 6.6
UniRef50_Q54Q21 Cluster: Putative uncharacterized protein; n=1; ... 33 8.8
UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.8
>UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69;
Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo
sapiens (Human)
Length = 246
Score = 313 bits (768), Expect = 4e-84
Identities = 142/213 (66%), Positives = 174/213 (81%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ GLTSVA RG D AV+ Q+KVPD+LLD ++VTHLF +T+ IGCVMTGM ADSRSQV R
Sbjct: 34 QGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQR 93
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
ARYEAANW+YKYG EIPV +LC+RIADISQVYTQNAEMRPLGC M+LI D+E GP VYK
Sbjct: 94 ARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYK 153
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
DP+GYYC +KA AAG K + ++LEKK+KK+ D + + ++ AI+CLS VLS+DFK S
Sbjct: 154 CDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPS 213
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
EIE+GVV+ +NP FR+LTE EID HL A+AE+D
Sbjct: 214 EIEVGVVTVENPKFRILTEAEIDAHLVALAERD 246
Score = 70.1 bits (164), Expect = 6e-11
Identities = 32/35 (91%), Positives = 33/35 (94%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
M+R SSAGFDRHITIFSPEGRLYQVEYA KAINQG
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQG 35
>UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15;
Eukaryota|Rep: Proteasome subunit alpha type-6-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 231 bits (565), Expect = 2e-59
Identities = 111/212 (52%), Positives = 151/212 (71%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
AG+TS+ RG D+ V Q+KVPD+LLD +SVTHLF +T IG V TG+ AD+RS V +A
Sbjct: 35 AGITSIGVRGKDSVCVVTQKKVPDKLLDQSSVTHLFPITKYIGLVATGITADARSLVQQA 94
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
R +AA +++ YG E+PV IL + IAD SQVYTQ+A MRPLG M++ D+E GP +YK
Sbjct: 95 RNQAAEFRFTYGYEMPVDILAKWIADKSQVYTQHAYMRPLGVVAMVMGVDEENGPLLYKC 154
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
DP+G++ +KA +AG K + +LEKK+K+ + D+ +Q AIS L VL DFK++E
Sbjct: 155 DPAGHFYGHKATSAGMKEQEAVNFLEKKMKENPSFTFDETVQTAISALQSVLQEDFKATE 214
Query: 729 IEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
IE+GVV +NP FR LT EI+ HLTAI+E+D
Sbjct: 215 IEVGVVRAENPEFRALTTEEIEEHLTAISERD 246
Score = 59.3 bits (137), Expect = 1e-07
Identities = 26/41 (63%), Positives = 31/41 (75%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAINQGWVDICG 208
M+R S AG+DRHITIFSPEGRL+QVEYA KA+ + G
Sbjct: 1 MSRGSGAGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIG 41
>UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9;
Bilateria|Rep: Proteasome subunit alpha type-6 -
Caenorhabditis elegans
Length = 246
Score = 224 bits (547), Expect = 2e-57
Identities = 98/210 (46%), Positives = 151/210 (71%)
Frame = +3
Query: 195 LTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
LT+VA +G DAAV+A Q++VPD L+ +VT ++ ++ +GC GMI D++ Q+ RA+
Sbjct: 37 LTAVAVKGADAAVIAVQKRVPDSLIVADTVTSVYQISQSVGCCAIGMIPDAKFQIKRAQG 96
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
EAA+W+YK G ++P +L +++AD++Q YTQNAEMR LGC+++ I+YDDE GP VY+ DP
Sbjct: 97 EAASWKYKNGYDMPCELLAKKMADLNQYYTQNAEMRSLGCALLFISYDDEKGPEVYRVDP 156
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIE 734
+GYY K V+ G K + ++LEKK+KK+S+L++ +AI+LAI L L +D +S ++E
Sbjct: 157 AGYYRGMKGVSVGVKQLPATSFLEKKIKKKSELTSTEAIELAIEALQTSLGIDVRSKDLE 216
Query: 735 IGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
+ VV+KDN F LT +++ HL IA +D
Sbjct: 217 VVVVTKDNSKFTKLTSDQVEHHLNQIANRD 246
Score = 64.5 bits (150), Expect = 3e-09
Identities = 29/33 (87%), Positives = 31/33 (93%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAIN 184
M+R SSAGFDRHITIFSPEGR+YQVEYA KAIN
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRVYQVEYAFKAIN 33
>UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome
undetermined scaffold_17, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 245
Score = 207 bits (505), Expect = 3e-52
Identities = 95/212 (44%), Positives = 144/212 (67%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
+GLTS+ +GTD + +++VPD+L+D SVT+LF ++++IG + TG+ +D+R+ V R
Sbjct: 34 SGLTSIGVKGTDTVCLITEKRVPDKLIDEKSVTNLFNVSEKIGALTTGIPSDARALVTRM 93
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
RYEA ++ K G PV +L +R+AD++Q TQ +MR G +L YDDE GP +YK
Sbjct: 94 RYEAGEFRLKNGYYCPVDVLSKRMADLAQTNTQYYQMRSYGVETILCQYDDELGPLLYKL 153
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
DPSG+Y YKA A+G K + YLEK++KK++DL+ D+ I LAI L V+S DFK ++
Sbjct: 154 DPSGHYSGYKATASGVKEQEAINYLEKQIKKKADLNYDETIMLAIQTLQNVISQDFKPTD 213
Query: 729 IEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
IE+G+V+K + F LT ++D +L IA +D
Sbjct: 214 IEVGIVTKQDKKFHKLTNEQVDHYLNLIANRD 245
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/27 (70%), Positives = 23/27 (85%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAI 181
S G + +IT+FSPEGRLYQVEYA KA+
Sbjct: 5 SQGHEFYITLFSPEGRLYQVEYAFKAV 31
>UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3;
Eukaryota|Rep: Proteasome subunit alpha type - Emiliania
huxleyi
Length = 264
Score = 206 bits (503), Expect = 5e-52
Identities = 106/223 (47%), Positives = 147/223 (65%), Gaps = 11/223 (4%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
+GLTSV RG D VV QRKVPD+L DP SVT+++A+T IG VMTG++ D+R+ V +
Sbjct: 35 SGLTSVGVRGADPCVVLTQRKVPDKLYDPESVTNMYAITPNIGLVMTGIVPDARASVKKL 94
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG---PCV 539
R EAA +++ G +IPV L +R AD +QVYTQ+A MRPLG +M++I D E P +
Sbjct: 95 REEAAKFKFNNGYDIPVSYLAKRAADTAQVYTQHANMRPLGIAMIIIGIDVEGEKKVPQL 154
Query: 540 YKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRS--------DLSTDDAIQLAISCLS 695
++ DP+GYY YKA +AGAK + N +LEK+ K + LS DD +QLA++CL
Sbjct: 155 FRCDPAGYYVGYKATSAGAKEQEANNFLEKRFKPPAGSNVAVDPKLSHDDTVQLALACLQ 214
Query: 696 QVLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
VL D K+++IE VV DN F L+ E++ LTA+AE+D
Sbjct: 215 NVLGADLKANDIEACVVRHDNLAFTRLSADELETQLTALAERD 257
Score = 63.3 bits (147), Expect = 7e-09
Identities = 29/32 (90%), Positives = 30/32 (93%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAI 181
MAR SSAG+DRHITIFSPEGRLYQVEYA KAI
Sbjct: 1 MARGSSAGYDRHITIFSPEGRLYQVEYAFKAI 32
>UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha1 -
Cryptosporidium parvum Iowa II
Length = 252
Score = 200 bits (488), Expect = 3e-50
Identities = 100/218 (45%), Positives = 141/218 (64%), Gaps = 6/218 (2%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVP------DRLLDPASVTHLFALTDRIGCVMTGMIADSR 350
+ +T++A +G D + ++KVP D+LLDPA VT L+ + IG VM G+ D R
Sbjct: 35 SNITAIAIKGKDTVCIVCEKKVPNQQGQQDKLLDPAYVTSLYKVRKHIGAVMLGLAPDCR 94
Query: 351 SQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG 530
S + + R A + ++ G EIPV L +IAD++Q+YTQ+A MR LG S M I+ DDE G
Sbjct: 95 SIISKCREIAGKFAFEKGVEIPVSYLSHKIADVNQLYTQHASMRLLGASGMFISIDDEDG 154
Query: 531 PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV 710
P +YK DP+GY+ SY+A A G K +GN LEK +K S ++ I +I CL +L V
Sbjct: 155 PSLYKIDPAGYFASYRACAVGTKEREGNNALEKIIKNEPLNSCEEVISASIDCLKTLLGV 214
Query: 711 DFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
DFK+ +IE+GVV+KD P FR+L+ EID +LT IAE+D
Sbjct: 215 DFKAEDIEVGVVTKDMPEFRLLSVEEIDNYLTNIAERD 252
Score = 48.4 bits (110), Expect = 2e-04
Identities = 20/32 (62%), Positives = 26/32 (81%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAI 181
M+R S + DRHITIFSPEG+LYQ+EY +A+
Sbjct: 1 MSRLSQSLHDRHITIFSPEGKLYQIEYTFRAV 32
>UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Ustilago maydis (Smut fungus)
Length = 305
Score = 187 bits (455), Expect = 3e-46
Identities = 88/182 (48%), Positives = 124/182 (68%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
AGLTS+A RG D +VV Q+KVPD+L+D +SVT++F LT IGC+MTG +AD+R+QV RA
Sbjct: 32 AGLTSIAVRGKDCSVVVGQKKVPDKLIDASSVTNIFNLTPEIGCIMTGRVADARAQVQRA 91
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
+ EAA+++YKYG I +L +R+A+++QVYTQ A MRP G SM+L+ D E GP ++K
Sbjct: 92 KMEAADFKYKYGYAITPDLLAKRMANMNQVYTQRAAMRPYGVSMILVGIDAERGPQIFKI 151
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
DP+GYY ++A AAG K + +LEK+ KK S +T DA + + D + E
Sbjct: 152 DPAGYYVGFRATAAGVKQTEATNFLEKQFKKSSTTTTGDAASAVPEAPAGASATDAAALE 211
Query: 729 IE 734
E
Sbjct: 212 AE 213
Score = 50.8 bits (116), Expect = 4e-05
Identities = 21/29 (72%), Positives = 26/29 (89%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAIN 184
S + +DR++TIFSP+GRLYQVEYA KAIN
Sbjct: 2 SRSSYDRYLTIFSPDGRLYQVEYAFKAIN 30
>UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 242
Score = 180 bits (439), Expect = 3e-44
Identities = 84/210 (40%), Positives = 138/210 (65%)
Frame = +3
Query: 195 LTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
LT+V +AA + Q+K+PDRL+DP++VTHL ++ +GC M+G+ AD + R++Y
Sbjct: 34 LTTVGVCSDEAACIITQKKLPDRLVDPSTVTHLHRISKHVGCCMSGIYADGKVIAQRSQY 93
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
A+ +Q YG E+PV ++ ++ AD +Q+ TQ+A MRP G S M I +D+ +GP ++++DP
Sbjct: 94 YASKFQLDYGYEMPVSLVAKKTADFAQMLTQHAYMRPFGVSSMFIGWDEVSGPQLWRSDP 153
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIE 734
+G +++ AAG K + LEKK K +L+ D + A+ CL V S +FK+++IE
Sbjct: 154 AGSVAAFRGCAAGEKEQEAFNNLEKK-KITKELTVDQVVCQALDCLQTVTSSEFKATDIE 212
Query: 735 IGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
I +V+KDN F +L++ EI+ +L +EKD
Sbjct: 213 IAIVTKDNKLFHLLSQQEIEHYLVLASEKD 242
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/27 (77%), Positives = 24/27 (88%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKA 178
+ G+DR +TIFSPEGRLYQVEYALKA
Sbjct: 2 AGTGYDRQLTIFSPEGRLYQVEYALKA 28
>UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3;
Piroplasmida|Rep: Proteasome subunit alpha type -
Theileria annulata
Length = 276
Score = 152 bits (369), Expect = 9e-36
Identities = 90/240 (37%), Positives = 135/240 (56%), Gaps = 30/240 (12%)
Frame = +3
Query: 195 LTSVAXRGTDAAVVAAQRKVP------DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQ 356
LT +A + A V AQ+K+P D LLD +SVT L+ +TD I ++ G+ D S
Sbjct: 37 LTGLAIKDDSAIAVVAQKKLPAQQGNQDVLLDTSSVTSLYHITDEIFALLVGLPGDCLSI 96
Query: 357 V*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPC 536
+ +AR A ++ YKYG IP +LC++I+D++QVYTQ+A MR C+ ++++ + + GP
Sbjct: 97 LYKARQVALDYSYKYGINIPASVLCQKISDLNQVYTQHAYMRLHACTGLILSIEPDVGPK 156
Query: 537 VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAI--------------- 671
+YK D SG++ YKA GAK + LEK LK+R +S DA+
Sbjct: 157 IYKFDSSGWFAGYKACGIGAKEQESENALEKTLKRREAMSLQDAMKSNLHVNTEVHQLSQ 216
Query: 672 ----QLAISCLSQVLSVD-----FKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
++ I L ++ +D +S IE+ V SKDNP FR L+E EI+ +LT I E D
Sbjct: 217 GQETKVTIEALRCMIDIDAFTKGLGASSIEVAVASKDNPFFRQLSEEEIETYLTHITESD 276
Score = 56.4 bits (130), Expect = 8e-07
Identities = 23/32 (71%), Positives = 30/32 (93%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAI 181
M+R S +G+DRHITIFSPEG+L+Q+EYALKA+
Sbjct: 1 MSRASHSGYDRHITIFSPEGKLFQLEYALKAV 32
>UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza
sativa|Rep: Proteasome subunit alpha type - Oryza sativa
subsp. japonica (Rice)
Length = 253
Score = 145 bits (352), Expect = 1e-33
Identities = 77/192 (40%), Positives = 119/192 (61%), Gaps = 1/192 (0%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
AG+TSV RG D+ V RK D+L DP ++T+LFA+TDRIG + TGM D R+ A
Sbjct: 49 AGITSVGVRGDDSVYVLTHRK-EDKLHDPTTITNLFAITDRIGLLATGMPGDGRAIAQEA 107
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG-PCVYK 545
R AA +++K+G ++ +L + IAD +Q+ TQ+A++RP G M+ D+E G P ++
Sbjct: 108 RNAAAEFRFKWGYKMSPCMLAQWIADRAQIRTQHAQIRPYGVVSMIFGIDEEKGTPELFT 167
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
DP+G + ++KA +AG K + +LE+++K + LS+ LA S L VL DF +
Sbjct: 168 CDPAGQFFAHKATSAGPKEKEVMNFLEERMKSKPSLSSGTTKGLAKSALKHVLEGDFYAR 227
Query: 726 EIEIGVVSKDNP 761
E E+G + K +P
Sbjct: 228 EFELGFIKKGDP 239
Score = 38.3 bits (85), Expect = 0.23
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQGWVDICG 208
A ++R IT+FSPEGRL Q++YA A+ + G
Sbjct: 21 ADYERFITLFSPEGRLCQLDYAFNAVKLAGITSVG 55
>UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 241
Score = 145 bits (351), Expect = 1e-33
Identities = 76/215 (35%), Positives = 129/215 (60%), Gaps = 2/215 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+A +T+VA + +A VA Q+KV D+L+DP++VTH++ +TD +G + G+ +D V
Sbjct: 30 QAEVTAVAVKSKNAVCVAVQKKVSDKLIDPSTVTHMYRITDNVGACLVGLPSDVNFIVML 89
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGP-CVY 542
R A N++YK G IPV IL + +++ Q+ +Q +RP S +L D + +Y
Sbjct: 90 LRSFANNFEYKQGFSIPVSILAQMLSERHQLESQLVYVRPSAVSAILFGLDGPSDSFALY 149
Query: 543 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDA-IQLAISCLSQVLSVDFK 719
K +PSGY ++AVA G K ++ + LEKK++ D T +A + +S L V VDF+
Sbjct: 150 KIEPSGYSNGFRAVACGVKEIEAMSALEKKME---DFETPEATAEFTLSTLQTVCGVDFE 206
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
+ ++E+ ++++DN F L +++ L A+AEKD
Sbjct: 207 AQDVEVSLLTRDNSKFSKLPNDKVNEILHAVAEKD 241
Score = 45.6 bits (103), Expect = 0.002
Identities = 19/32 (59%), Positives = 26/32 (81%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQGWV 196
S+G DR++T+FS EGRL+QVEY+ KA+ Q V
Sbjct: 2 SSGADRYLTVFSAEGRLWQVEYSFKAVKQAEV 33
>UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;
Eukaryota|Rep: Alpha 2 subunit of 20S proteasome -
Ostreococcus tauri
Length = 270
Score = 137 bits (331), Expect = 4e-31
Identities = 76/208 (36%), Positives = 112/208 (53%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
AG TS+ + D V+A ++K+P L+D ++V + LTD IG +GM D R A
Sbjct: 66 AGATSLGIKAVDGVVLATEKKLPSTLVDASTVKKIATLTDDIGIAYSGMGPDFRVLTRMA 125
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
R E + Y IPV L R A + Q +TQ +RP G S+++ Y DE+GP +Y+
Sbjct: 126 RKETQTYYRTYKESIPVSQLVRETATVMQEFTQQGGVRPFGVSLLMAGY-DESGPSLYQV 184
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
DPSG Y ++KA A G V+ +LEK+ D+ +DAI AI L + +
Sbjct: 185 DPSGSYFAWKASAIGKNMVNAKTFLEKRYS--DDIELEDAIHTAILTLKEGFDGQISADN 242
Query: 729 IEIGVVSKDNPXFRVLTETEIDRHLTAI 812
IEIG+V D FR+L+ +EI +L +
Sbjct: 243 IEIGIVGADR-KFRILSTSEIADYLEEV 269
>UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5;
Plasmodium|Rep: Proteasome subunit alpha, putative -
Plasmodium falciparum (isolate 3D7)
Length = 284
Score = 135 bits (326), Expect = 1e-30
Identities = 89/248 (35%), Positives = 128/248 (51%), Gaps = 38/248 (15%)
Frame = +3
Query: 195 LTSVAXRGTDAAVVAAQRKVP------DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQ 356
+TSV +G + AV+ +Q+K+ D+LLD ++T+++ +TD IGC M GM D S
Sbjct: 37 ITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSM 96
Query: 357 V*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSM------------ 500
V +AR EA+ + Y G + LCR I D QVYTQ+A MR CS
Sbjct: 97 VYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSNIYIYIYMNICTC 156
Query: 501 ------------MLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR 644
M+I D+ P ++K DPSG+ Y+A G K + + LE+ L+KR
Sbjct: 157 VFIFLHKCVKCGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKR 216
Query: 645 SDLSTDDAIQ--------LAISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDRH 800
+ I LAI L +L+ D K+SEIE+ +VS N F ++E EID +
Sbjct: 217 KKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKEIDNY 276
Query: 801 LTAIAEKD 824
LT IAE+D
Sbjct: 277 LTYIAERD 284
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/48 (45%), Positives = 31/48 (64%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAINQGWVDICGXTRYRCS 229
M R S + +DRH+TIFSP+G LYQ+EYA+KA+ + G C+
Sbjct: 1 MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCA 48
>UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei brucei
Length = 266
Score = 129 bits (312), Expect = 7e-29
Identities = 76/219 (34%), Positives = 123/219 (56%), Gaps = 7/219 (3%)
Frame = +3
Query: 183 TRAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV* 362
T AGL +VA R DA +V Q VPD+L+ P ++T L+ + D G +TG D ++ V
Sbjct: 30 TYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPETITSLYNVNDNTGVCITGRAPDGKALVQ 89
Query: 363 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYD--DEAG-- 530
+AR EA+ ++Y+YG + V +L + D++QV TQ A MR +G M + + DE G
Sbjct: 90 KARNEASEYKYRYGMPMLVSVLAKPWQDMAQVRTQQAGMRLMGTIMTFVGMEQNDEDGAW 149
Query: 531 -PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKR--SDLSTDDAIQLAISCLSQV 701
P +Y DP+G + A A G K ++ A+LEKK K LS +A +A++ L
Sbjct: 150 IPQIYCVDPAG-GAAVHACAVGKKQIEACAFLEKKQKNAPFHTLSQKEAAMIALAALQSA 208
Query: 702 LSVDFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAE 818
L ++S +E+G + D+ F +++ E+ + LT +A+
Sbjct: 209 LGESLRASGVEVGRCTADDHHFLRVSDREVKKWLTPLAK 247
Score = 50.8 bits (116), Expect = 4e-05
Identities = 21/28 (75%), Positives = 25/28 (89%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAI 181
S AGFD++IT+FSPEG LYQVEYA KA+
Sbjct: 2 SRAGFDKYITVFSPEGSLYQVEYAFKAV 29
>UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29;
Archaea|Rep: Proteasome subunit alpha - Methanococcus
jannaschii
Length = 261
Score = 123 bits (297), Expect = 5e-27
Identities = 66/212 (31%), Positives = 119/212 (56%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G T++ D V+A R++ +L+ S+ +F + D + +G++AD+R + R
Sbjct: 33 RRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR EA ++ YG EI + +L ++I DI Q YTQ+ +RP G S +LIA D+ +++
Sbjct: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVS-LLIAGIDKNEARLFE 151
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG YKA A G+ LEK+ R D++ D+ ++LAI+ L++ + D K
Sbjct: 152 TDPSGALIEYKATAIGSGRPVVMELLEKEY--RDDITLDEGLELAITALTKA-NEDIKPE 208
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
+++ +++ + F+ + EI + + + +K
Sbjct: 209 NVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240
Score = 47.2 bits (107), Expect = 5e-04
Identities = 19/29 (65%), Positives = 25/29 (86%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQG 190
+ +DR IT+FSPEGRLYQVEYA +A+ +G
Sbjct: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRG 35
>UniRef50_P23638 Cluster: Proteasome component Y13; n=3;
Saccharomycetaceae|Rep: Proteasome component Y13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 258
Score = 123 bits (297), Expect = 5e-27
Identities = 65/168 (38%), Positives = 96/168 (57%), Gaps = 1/168 (0%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTH-LFALTDRIGCVMTGMIADSRSQV*RARY 374
T++ +D V+AA+RKV LL+ + T L+ L D+I + G+ AD+ + AR
Sbjct: 34 TAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARI 93
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
A N+ Y +IPV IL RR++DI Q YTQ+ +RP G S + YDD G +Y ++P
Sbjct: 94 HAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNP 153
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQ 698
SG Y +KA++ GA T L+ K D+ DDAI+LA+ LS+
Sbjct: 154 SGNYTGWKAISVGANTSAAQTLLQMDYK--DDMKVDDAIELALKTLSK 199
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/28 (67%), Positives = 23/28 (82%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAIN 184
S +D TIFSPEGRLYQVEYAL++I+
Sbjct: 3 SRRYDSRTTIFSPEGRLYQVEYALESIS 30
>UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54;
Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo
sapiens (Human)
Length = 234
Score = 123 bits (296), Expect = 6e-27
Identities = 74/208 (35%), Positives = 111/208 (53%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G SV + + V+A ++K L D SV + +T IG V +GM D R V RAR
Sbjct: 32 GAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRAR 91
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
A + Y IP L +R+A + Q YTQ+ +RP G S+++ + +E P ++++D
Sbjct: 92 KLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGW-NEGRPYLFQSD 150
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG Y ++KA A G V+G +LEK+ + DL +DAI AI L + I
Sbjct: 151 PSGAYFAWKATAMGKNYVNGKTFLEKRYNE--DLELEDAIHTAILTLKESFEGQMTEDNI 208
Query: 732 EIGVVSKDNPXFRVLTETEIDRHLTAIA 815
E+G+ ++ FR LT TE+ +L AIA
Sbjct: 209 EVGICNE--AGFRRLTPTEVKDYLAAIA 234
Score = 34.3 bits (75), Expect = 3.8
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQG 190
G+ +T FSP G+L Q+EYAL A+ G
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGG 32
>UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8;
Euryarchaeota|Rep: Proteasome subunit alpha -
Methanococcus maripaludis
Length = 259
Score = 116 bits (279), Expect = 7e-25
Identities = 63/212 (29%), Positives = 113/212 (53%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G T+V + D V+A R++ +L+D +S+ +F + D I +G++AD+R + R
Sbjct: 34 RRGTTAVGIKCKDGVVLAVDRRITSKLIDVSSIEKIFQIDDHIVAATSGLVADARVLIDR 93
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR EA + YG I V L ++I DI Q YTQ+ RP G ++++ D + +++
Sbjct: 94 ARIEAQMNRVSYGEAITVEALAKKICDIKQAYTQHGGARPFGLALLITGIDRHSAR-LFE 152
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG YKA A G+ LE K + +++ + ++LA+ LS+ + + K
Sbjct: 153 TDPSGALIEYKATAIGSGRPIAMEVLESKYDE--NMTVSEGMELALYALSKT-TEELKPE 209
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
I++ ++ ++ EI++ + A+ EK
Sbjct: 210 NIDMAIIKDSGKLVEKISVDEIEKIVKAVYEK 241
Score = 50.4 bits (115), Expect = 5e-05
Identities = 21/30 (70%), Positives = 27/30 (90%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQG 190
++G+DR ITIFSPEGRLYQVEYA +A+ +G
Sbjct: 7 ASGYDRAITIFSPEGRLYQVEYAREAVRRG 36
>UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1;
Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha
subunit - Hyperthermus butylicus (strain DSM 5456 / JCM
9403)
Length = 243
Score = 116 bits (278), Expect = 1e-24
Identities = 64/206 (31%), Positives = 108/206 (52%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T V R D V+ A++K L+D + ++ + + IG G +D R +
Sbjct: 36 KRGWTMVGVRARDGVVIVAEKKKTSPLIDIEQLEKVYMVDEHIGAGFVGFGSDGRVLIDY 95
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR A +++ YG +IPV L R+I D+ Q+YTQ+ +RP G +++++ DD +GP ++
Sbjct: 96 ARQLAIQYKFIYGEKIPVEYLTRQICDLMQLYTQHGGVRPFGVTLLIVGVDD-SGPKLFV 154
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
+PSG Y SYKA G G A + + R D+ + AI L I ++ V+
Sbjct: 155 AEPSGQYMSYKAHGLGQG--GGQAIEILQREYRDDIDVEGAILLGIRAVASVMEGKPTPE 212
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHL 803
+E+GV FR LT+ E+ +++
Sbjct: 213 TLEVGVADTRTGRFRKLTKEELLKYI 238
Score = 46.4 bits (105), Expect = 9e-04
Identities = 17/29 (58%), Positives = 24/29 (82%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQGW 193
G+DR +FSP+GRL+QVEYA++A +GW
Sbjct: 11 GYDRSTAMFSPDGRLFQVEYAMEAAKRGW 39
>UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia
intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia
ATCC 50803
Length = 247
Score = 115 bits (277), Expect = 1e-24
Identities = 69/213 (32%), Positives = 110/213 (51%), Gaps = 4/213 (1%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
+GL+ VA R D V+ +Q + DRL+D A+ T + + + C++ G IAD R + R
Sbjct: 33 SGLSHVAIRCLDGVVLVSQLQSADRLVDTANNTFIHEINETSACMICGRIADGRRVIDRV 92
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG-PCVYK 545
R EA ++ K+ + ILC R+ADI+Q+YTQ A RP G + +D E ++K
Sbjct: 93 RSEAVDFFRKWNYQPTADILCTRLADINQIYTQEAWQRPFGNIAVFAGWDPEQDRSLLFK 152
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD---LSTDDAIQLAISCLSQVLSVDF 716
TDP+G Y A+A G K V+ L ++K + ST + A+ V+S
Sbjct: 153 TDPAGTNTGYFAIAVGVKEVELADALTVQVKSFPNGICESTQKGLDCALKIFQNVISTGL 212
Query: 717 KSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIA 815
++E+ + +K + LT E+DR L +A
Sbjct: 213 TGDDVEVAIYTKTG--LKRLTPIEVDRRLGELA 243
Score = 42.7 bits (96), Expect = 0.011
Identities = 15/28 (53%), Positives = 25/28 (89%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAI 181
++ GFD+ +T+F+PEG+L+QVEYA +A+
Sbjct: 3 TTEGFDQALTVFNPEGKLFQVEYAFRAV 30
>UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24;
Bilateria|Rep: Proteasome subunit alpha type-7 -
Carassius auratus (Goldfish)
Length = 251
Score = 115 bits (276), Expect = 2e-24
Identities = 69/213 (32%), Positives = 113/213 (53%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T+V RG D V+ ++K +L + +V + AL + + G+ AD+R + R
Sbjct: 29 KKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVRKICALDEHVCMAFAGLTADARIVINR 88
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR E + + + V + R IA + Q YTQ+ RP G S +++ +D + P +Y+
Sbjct: 89 ARVECQSHRLTVEDPVTVEYITRYIATLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 148
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG Y ++KA A G +LEK + S +DAI+LAI L +V+ K+
Sbjct: 149 TDPSGTYHAWKANAIGRSAKTVREFLEKNYTDEAIASDNDAIKLAIKALLEVVQSGGKN- 207
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
IE+ V+ ++ P ++L EI+ L A EK+
Sbjct: 208 -IELAVIRRNQP-LKILESKEIET-LVAEIEKE 237
Score = 43.2 bits (97), Expect = 0.008
Identities = 17/30 (56%), Positives = 25/30 (83%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQG 190
+A +DR IT+FSP+G L+QVEYA +A+ +G
Sbjct: 2 AARYDRAITVFSPDGHLFQVEYAQEAVKKG 31
>UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48;
Eukaryota|Rep: Proteasome subunit alpha type-2 -
Drosophila melanogaster (Fruit fly)
Length = 234
Score = 113 bits (273), Expect = 4e-24
Identities = 70/207 (33%), Positives = 108/207 (52%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G SV ++ V+A + K L + SV + + + IG V +GM D R V +AR
Sbjct: 32 GAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIYNHIGMVYSGMGPDYRLLVKQAR 91
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
A + Y IPV L +R+A + Q YTQ+ +RP G S+++ +D++ P +Y++D
Sbjct: 92 KIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRPFGVSLLICGWDNDR-PYLYQSD 150
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG Y ++KA A G V+G +LEK+ + DL DDA+ AI L + + I
Sbjct: 151 PSGAYFAWKATAMGKNAVNGKTFLEKRYSE--DLELDDAVHTAILTLKEGFEGKMTADNI 208
Query: 732 EIGVVSKDNPXFRVLTETEIDRHLTAI 812
EIG+ D F+ L I +L +I
Sbjct: 209 EIGIC--DQNGFQRLDPASIKDYLASI 233
>UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4;
Thermoplasmatales|Rep: Proteasome subunit alpha -
Picrophilus torridus
Length = 234
Score = 111 bits (268), Expect = 2e-23
Identities = 66/206 (32%), Positives = 111/206 (53%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T++ + D + +++KV RL++ S+ + + DR+ V +G++AD+R +
Sbjct: 32 KKGSTALGIKFKDGVALISEKKVRSRLVEKTSLEKIQLIDDRVAAVTSGLVADARVLIDF 91
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR + YGS + + L +R+AD Q YTQ +RP G S ++ A D GP ++
Sbjct: 92 ARISDQQEKVTYGSLMNIENLVKRVADQMQQYTQYGGVRPYGVS-IIFAGLDSIGPRLFD 150
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
DP+G YK V+ GA AYLEK+ K+ +LS D+AI++ I+ L ++ +
Sbjct: 151 CDPAGTINEYKCVSIGAGKDQVTAYLEKEYKE--NLSEDEAIRMGIAALKSAVADESSMK 208
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHL 803
E EI + K F V T E+ ++L
Sbjct: 209 EPEIASI-KMGETFHVFTSEEVSKYL 233
Score = 44.8 bits (101), Expect = 0.003
Identities = 17/33 (51%), Positives = 26/33 (78%)
Frame = +2
Query: 92 RESSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
++ +DR IT+FSP+GRL+QVEYA +A+ +G
Sbjct: 2 QQGQMAYDRAITVFSPDGRLFQVEYAREAVKKG 34
>UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like;
n=116; Eukaryota|Rep: Proteasome subunit alpha
type-7-like - Homo sapiens (Human)
Length = 256
Score = 108 bits (260), Expect = 1e-22
Identities = 67/218 (30%), Positives = 118/218 (54%), Gaps = 6/218 (2%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIG---CVMT---GMIADS 347
+ G T+V RGT+ V+ ++K +L D +V + AL D + V+T G+ AD+
Sbjct: 29 KKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAVLTIFIGLTADA 88
Query: 348 RSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEA 527
R + RAR E + + + V + R IA + Q YTQ+ RP G S +++ +DD+
Sbjct: 89 RVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDG 148
Query: 528 GPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLS 707
+Y+TDPSG Y ++KA A G +LEK + + S +AI+LAI L +V+
Sbjct: 149 ISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQ 208
Query: 708 VDFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
K+ IE+ ++ ++ P ++ + E++ ++T I ++
Sbjct: 209 SGGKN--IELAIIRRNQP-LKMFSAKEVELYVTEIEKE 243
Score = 41.9 bits (94), Expect = 0.019
Identities = 16/27 (59%), Positives = 23/27 (85%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR IT+FSP+G L+QVEYA +A+ +G
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKG 31
>UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2;
Giardia intestinalis|Rep: Proteasome subunit alpha type
- Giardia lamblia ATCC 50803
Length = 214
Score = 108 bits (259), Expect = 2e-22
Identities = 63/182 (34%), Positives = 101/182 (55%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G ++VA R V+A +RK RL DP + +F + D I G+ AD+R + RAR
Sbjct: 31 GTSAVAVRSAAGIVLAIERKQTARLQDPRASQKIFDVDDHIIATFAGLTADARVLIDRAR 90
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
E ++ Y V I+ + +A I Q +T RP G S++L A +D G V+ D
Sbjct: 91 LECQAYRMTYDVAPSVEIIAKAVASILQSHTHRGGTRPFGVSIIL-AGNDLNGSHVFMCD 149
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG Y +KA+A G + V +LEKKLK+ +T+DA+ LA + LS+++ V+ ++ +
Sbjct: 150 PSGVYTEWKALAIGNQCVTIIEFLEKKLKEGEPQNTNDALSLAKAALSELIDVNDETFQC 209
Query: 732 EI 737
++
Sbjct: 210 KV 211
Score = 37.5 bits (83), Expect = 0.41
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQG 190
S +D +T+FSP+G L QVE+A KA+ +G
Sbjct: 2 SGKYDSSLTVFSPDGHLIQVEHAHKAVERG 31
>UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6;
Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus
acidocaldarius
Length = 242
Score = 107 bits (256), Expect = 4e-22
Identities = 63/203 (31%), Positives = 98/203 (48%), Gaps = 2/203 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T++ + V+ A+++ +LLD + +F L D +GC G+ +D R +
Sbjct: 34 KRGWTTLGVKTKSGVVLLAEKRKATQLLDVDGIEKIFMLDDHVGCTFAGLASDGRILIDY 93
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR +A + Y I + L + I+D+ Q YTQ+ +RP G ++++ D P +
Sbjct: 94 ARSQALQHRLIYDEPISIEYLTKVISDVKQAYTQHGGVRPFGVALIVGGIDKGKQPKLLM 153
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFK-- 719
T+PSG + Y AVA G YLEK K+ DL I LA+ L L K
Sbjct: 154 TEPSGQFMPYYAVAIGQGGYTATEYLEKNYKE--DLDIQSTILLALRALMATLKPGEKLN 211
Query: 720 SSEIEIGVVSKDNPXFRVLTETE 788
S +EIG D+ F+ LT E
Sbjct: 212 YSSVEIGYADVDSGTFKKLTTEE 234
Score = 50.8 bits (116), Expect = 4e-05
Identities = 19/35 (54%), Positives = 28/35 (80%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
++ G+DR ITIFSP+G LYQV+YA +A+ +GW +
Sbjct: 6 AAMGYDRAITIFSPDGSLYQVDYAFEAVKRGWTTL 40
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 106 bits (255), Expect = 6e-22
Identities = 66/215 (30%), Positives = 104/215 (48%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G S+ R +D V+A +++ L++ +SV + D IG G +AD+R +
Sbjct: 34 KRGTASIGVRTSDGVVLAVDKRIRSPLMERSSVEKIHKADDHIGIASAGHVADARQLIDF 93
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR +A Q +YG + V L + I D Q YTQ RP G + ++I P +++
Sbjct: 94 ARRQAQVNQLRYGEPVGVETLTKEITDYIQQYTQVGGARPFGVA-LIIGGIVNGEPRLFE 152
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG +KA+A GA D YLE+ + DL D+ + LA++ L+ V +
Sbjct: 153 TDPSGTPYEWKALAVGADRGDIRDYLEEHYDEGMDL--DEGVDLALAALASVNDDELSPE 210
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKDXG 830
I + V + F LT+ E + HL D G
Sbjct: 211 GIGVATVDVETETFGQLTDEEKEAHLAEADLLDTG 245
Score = 46.8 bits (106), Expect = 7e-04
Identities = 20/31 (64%), Positives = 25/31 (80%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+DR ITIFSP+GRLYQVEYA +A+ +G I
Sbjct: 10 YDRGITIFSPDGRLYQVEYAREAVKRGTASI 40
>UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7;
n=3; Ascomycota|Rep: Probable proteasome subunit alpha
type-7 - Schizosaccharomyces pombe (Fission yeast)
Length = 259
Score = 106 bits (254), Expect = 8e-22
Identities = 60/188 (31%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G T++A RG + V+ +RK +L + ++ + + + + G+ AD+R + +
Sbjct: 28 RRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMVDNHVCLAFAGLNADARILIDK 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYD-DEAGPCVY 542
AR EA N + + + L R +A + Q YTQ+ +RP G S ++ +D + P VY
Sbjct: 88 ARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVRPFGVSTLIAGFDVGDNTPRVY 147
Query: 543 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKS 722
+T+P+G Y ++KA A G + YLEK K+ LS D+ I LA+S L +V V S
Sbjct: 148 QTEPAGIYNAWKATAIGRASKAAREYLEKNWKE--GLSRDETIHLAVSSLLEV--VQTAS 203
Query: 723 SEIEIGVV 746
IE+ ++
Sbjct: 204 GNIELAIM 211
Score = 41.1 bits (92), Expect = 0.033
Identities = 15/29 (51%), Positives = 24/29 (82%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQG 190
+G+DR +++FSP+GRL QVEY +A+ +G
Sbjct: 2 SGYDRALSVFSPDGRLLQVEYGQEAVRRG 30
>UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2;
Eukaryota|Rep: Proteasome subunit alpha type-5 -
Entamoeba histolytica
Length = 247
Score = 106 bits (254), Expect = 8e-22
Identities = 61/217 (28%), Positives = 115/217 (52%), Gaps = 5/217 (2%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T + + + V+A ++++ L+ +S+ + + D IG ++G+ AD+R+ +
Sbjct: 32 KLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKIIEIDDHIGAAVSGLTADARTLIDN 91
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAE-----MRPLGCSMMLIAYDDEAG 530
AR EA N ++ Y I V ++ + I+D+S + + + RP G + +LIA DE G
Sbjct: 92 ARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSRKKKVMSRPFGVA-LLIAGVDETG 150
Query: 531 PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV 710
P +++TDPSG + + A A GA T + L +K K ++ +A LA+S L QV+
Sbjct: 151 PRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNK--SMTLREAEILALSTLKQVMEE 208
Query: 711 DFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
S +E+ +V+ + F ++ I+ + I E+
Sbjct: 209 KLNSKNVEVALVTVEKKKFEIMDTAFIENLIGEIKEE 245
Score = 33.1 bits (72), Expect = 8.8
Identities = 14/26 (53%), Positives = 18/26 (69%)
Frame = +2
Query: 113 DRHITIFSPEGRLYQVEYALKAINQG 190
D + FS EGRL+QVEYA +A+ G
Sbjct: 9 DHGVNTFSSEGRLFQVEYATEAMKLG 34
>UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;
n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta
subunit - Cenarchaeum symbiosum
Length = 245
Score = 104 bits (250), Expect = 2e-21
Identities = 66/212 (31%), Positives = 103/212 (48%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G +V + T V+A + K P RL ++ +F + D +G G I D+RSQV
Sbjct: 32 RRGTIAVGVKSTGGIVIAVEEK-PRRLQISDTIQKIFQVDDHLGVAAAGYIPDARSQVEN 90
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR+ + + + Y + V + + +AD Q +TQ A +RP G ++++ DD ++
Sbjct: 91 ARFFSQSNRMMYDESVEVEAVAKHLADQCQQFTQYAGVRPFGVALIIGGVDDGGKGQLFL 150
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG Y SY A+A GA + +LEK K S +DA LA + + S
Sbjct: 151 TDPSGTYISYDAIAIGAGSEQVTEFLEKSYKPG---SMEDAAVLAAAAIRIAGEETDTES 207
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
I + VS DN F ++ + E+ A K
Sbjct: 208 HIRMARVSADNRRFEMVPDGEVASFAAKAAAK 239
Score = 48.8 bits (111), Expect = 2e-04
Identities = 18/32 (56%), Positives = 27/32 (84%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
G+DR IT+FSP+GRLYQVEYA++ + +G + +
Sbjct: 7 GYDRAITVFSPDGRLYQVEYAIETVRRGTIAV 38
>UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum
pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix
Length = 258
Score = 104 bits (250), Expect = 2e-21
Identities = 55/187 (29%), Positives = 95/187 (50%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G TS+ + + V+AA+++ L+D + ++ + D IG GM D R +
Sbjct: 36 KKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKIYKIDDHIGVAFAGMGGDGRILIDY 95
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR + YG PV ++ + +AD+ Q YTQ+ +RP G +++ + + VY+
Sbjct: 96 ARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQHGGVRPFGVALIFAGVNPDGTTKVYR 155
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDP G Y S+KA+A G+ N EK RSD+S ++A +LA+ L ++ +
Sbjct: 156 TDPGGQYFSFKAIAIGSGEQVANEMFEKHY--RSDMSLEEATKLALKILYAIIRKTVEDK 213
Query: 726 EIEIGVV 746
E I +
Sbjct: 214 EKAIATL 220
Score = 46.4 bits (105), Expect = 9e-04
Identities = 18/31 (58%), Positives = 23/31 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+DR TIFSPEG LYQV YA +A+ +GW +
Sbjct: 12 YDRAATIFSPEGDLYQVRYAFEAVKKGWTSL 42
>UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 232
Score = 101 bits (241), Expect = 3e-20
Identities = 61/203 (30%), Positives = 103/203 (50%)
Frame = +3
Query: 204 VAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAA 383
V + + AV+A + K L++ + + + D +G V +G+ D + R +
Sbjct: 34 VGVKAKNGAVIACESKPSSPLVEKVTNLKVQKINDNVGIVYSGVNTDFHVILKSLRKASI 93
Query: 384 NWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGY 563
+ + G E+P + + A Q YTQ +RP G S+++I + +E GP +++ DPSG
Sbjct: 94 KYSLRLGVEMPTREVVKHAAHKMQYYTQIGGVRPFGVSLLIIGW-EELGPTLWQVDPSGT 152
Query: 564 YCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 743
+ ++KA A G ++ +LE++ + D S DDAI AIS L + + IEIGV
Sbjct: 153 FWAWKATALGKRSDGSRTFLERRYSE--DQSVDDAIHTAISTLKEGFDGQLTAELIEIGV 210
Query: 744 VSKDNPXFRVLTETEIDRHLTAI 812
V + FR L+ EI LT +
Sbjct: 211 VD-ETRKFRTLSTAEIRDFLTEV 232
>UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6;
Eukaryota|Rep: Proteasome subunit alpha type-1 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 98.7 bits (235), Expect = 2e-19
Identities = 56/216 (25%), Positives = 110/216 (50%), Gaps = 3/216 (1%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +VA + AV+ + ++ L + +F + D +G ++G+ AD+R
Sbjct: 30 KQGGAAVALKSKQFAVLVSLKRSSSEL--GSYQKKIFVVDDHVGIAISGLTADARMLCNY 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E +N+ Y Y S++ V L ++AD QV+TQ RP G +++ Y D+ G +Y+
Sbjct: 88 MRNECSNYNYVYESQMRVERLVTKVADKHQVHTQRYGRRPYGVGLLVAGY-DQLGAHIYQ 146
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVD--F 716
T PSG + YK+++ G+++ YLEK + + + + I + L + + + D
Sbjct: 147 TCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEECTLEQLITHGLRALRETIPNTDDTL 206
Query: 717 KSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
S + IG+V + P F+++ E + +L + ++
Sbjct: 207 NSKNVSIGIVGEGQP-FKIIEEADAQPYLNLLENEE 241
Score = 41.1 bits (92), Expect = 0.033
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D IT FSP GR++Q+EYA++A+ QG
Sbjct: 6 YDSDITTFSPSGRIHQIEYAMEAVKQG 32
>UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 283
Score = 63.7 bits (148), Expect(2) = 3e-19
Identities = 37/116 (31%), Positives = 64/116 (55%), Gaps = 2/116 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G+T++ + T+ V+A ++K L DP+S++ + +T IG V GM D R V +AR
Sbjct: 31 GVTALGIKATNGIVLATEKKSSSPLTDPSSLSKISLVTPNIGMVYAGMGPDYRVLVDKAR 90
Query: 372 YEAANWQYK--YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGP 533
+ ++ YK Y P IL + +A + Q TQ+ +RP G S+++ +D+ P
Sbjct: 91 -KVSHSGYKRIYNEYPPTRILVQDVARVVQEATQSGGVRPYGVSLLIAGWDEGIPP 145
Score = 54.8 bits (126), Expect(2) = 3e-19
Identities = 25/75 (33%), Positives = 40/75 (53%)
Frame = +3
Query: 522 EAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQV 701
+ GP +Y+ DPSG Y +KA A G +LEK+ + L +DA+ +A+ L +
Sbjct: 175 KGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYTE--GLELEDAVHIALLTLKET 232
Query: 702 LSVDFKSSEIEIGVV 746
+ + IEIG+V
Sbjct: 233 IEGEMNGDSIEIGIV 247
Score = 38.7 bits (86), Expect = 0.18
Identities = 15/23 (65%), Positives = 19/23 (82%)
Frame = +2
Query: 122 ITIFSPEGRLYQVEYALKAINQG 190
+T FSP G+L Q+EYAL A+NQG
Sbjct: 9 LTTFSPSGKLVQIEYALNAVNQG 31
>UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4;
Eukaryota|Rep: Proteasome subunit alpha type-4 -
Dictyostelium discoideum (Slime mold)
Length = 250
Score = 97.5 bits (232), Expect = 4e-19
Identities = 61/208 (29%), Positives = 107/208 (51%), Gaps = 6/208 (2%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPA-SVTH-LFALTDRIGCVMTGMIADSRSQV* 362
AG T V D V+AA++K +LLD + S++ +F + + + C + G+ +D+ +
Sbjct: 31 AGAT-VGILAKDGIVLAAEKKTTAKLLDSSTSISEKMFKIDEHVVCAVAGITSDANILIN 89
Query: 363 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY 542
AR + + Y+Y +PV L +I D Q YTQ +RP G S + +D G +Y
Sbjct: 90 YARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQYGGLRPFGVSFLYAGWDRHYGFQLY 149
Query: 543 KTDPSGYYCSYKAVAAGAKTVD-GNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLS-VDF 716
++DPSG + +KA + G + + L K D+S +A+QLA+ L++ + +
Sbjct: 150 QSDPSGNFAGWKATSIGGENSQVAQSVLRSNYK--PDISLKEALQLALKVLTKTMDRSNI 207
Query: 717 KSSEIEIGVVSK--DNPXFRVLTETEID 794
S ++E +K DN + + T E+D
Sbjct: 208 NSEKLEFSYFTKQGDNVVYHIFTAAELD 235
Score = 41.5 bits (93), Expect = 0.025
Identities = 17/24 (70%), Positives = 21/24 (87%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAI 181
+D+ TIFSPEGR+YQVEYA+ AI
Sbjct: 5 YDQRTTIFSPEGRVYQVEYAMTAI 28
>UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5;
Magnoliophyta|Rep: Proteasome subunit alpha type-4 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 250
Score = 97.5 bits (232), Expect = 4e-19
Identities = 51/185 (27%), Positives = 96/185 (51%), Gaps = 2/185 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPA-SVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
+++ D V+ ++KV +LL + S ++ + D + C + G+++D+ + AR
Sbjct: 33 SAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKMYKIDDHVACAVAGIMSDANILINTARV 92
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
+A + + Y +PV L + + D Q YTQ +RP G S + +D G +Y +DP
Sbjct: 93 QAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDP 152
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEI 731
SG Y +KA A GA + L++ K D + ++A++LA+ L++ + S S ++
Sbjct: 153 SGNYGGWKAAAVGANNQAAQSILKQDYK--DDATREEAVELALKVLTKTMDSTSLTSEKL 210
Query: 732 EIGVV 746
E+ V
Sbjct: 211 ELAEV 215
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/27 (70%), Positives = 22/27 (81%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAI 181
S +D TIFSPEGRLYQVEYA++AI
Sbjct: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAI 28
>UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2;
Sophophora|Rep: Proteasome subunit alpha type -
Drosophila melanogaster (Fruit fly)
Length = 289
Score = 97.1 bits (231), Expect = 5e-19
Identities = 61/215 (28%), Positives = 107/215 (49%), Gaps = 2/215 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTH-LFALTDRIGCVMTGMIADSRSQV* 362
+ G +V +GTD AV+AA + D ++ + + D +G + G+ AD+R
Sbjct: 30 KQGAATVGLKGTDYAVLAALCRTSK---DTNTLQRKIMPVDDHVGMSIAGLTADARVVCQ 86
Query: 363 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY 542
R E +++ Y +E PV L + + Q TQ + RP G +++ Y DE GP +Y
Sbjct: 87 YMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGVGLLVAGY-DEQGPHIY 145
Query: 543 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVDFK 719
+ P+ + KA+A G+++ YLE+ ++ D D+ I AI + L S D +
Sbjct: 146 QVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAIRGSLGSDDVE 205
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEKD 824
+ I + +V KD P F++ TE E +++ + D
Sbjct: 206 NLTINVAIVGKDVP-FKMFTEAENQKYVKLVKAMD 239
Score = 39.9 bits (89), Expect = 0.076
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D T +SP+GRL+QVEYA++A+ QG
Sbjct: 6 YDNDTTTWSPQGRLFQVEYAMEAVKQG 32
>UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7;
Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum
aerophilum
Length = 243
Score = 96.7 bits (230), Expect = 6e-19
Identities = 57/209 (27%), Positives = 107/209 (51%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +V + V+ A+++ L D +S+ ++ + + + +G++AD+R +
Sbjct: 33 KRGWPTVGVKCKAGVVLTAEKRKISALFDSSSLEKIYLIDEHVAASPSGLLADARILIDY 92
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
AR A + ++ Y I V L + + ++ Q YTQ RP G + +LIA D G +Y+
Sbjct: 93 ARDVALSHRFIYDEPIDVEFLTKAVCNLKQQYTQFGGARPFGVA-LLIAGVDRHGARLYQ 151
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
TDPSG Y Y A A GA++ +LEK K D+ + I+LA+ L+ + + S+
Sbjct: 152 TDPSGVYIGYFATAIGAESGTITEFLEKNYK--FDMEMGECIELALKALASAVEIT-DSA 208
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAI 812
+E+ + + R +++ E+ LT +
Sbjct: 209 NVEVAYATIEEKKMRKMSQDEVASLLTKL 237
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/30 (70%), Positives = 27/30 (90%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQGW 193
AG+DR ITIFSPEG++YQVEYA +A+ +GW
Sbjct: 7 AGYDRAITIFSPEGKIYQVEYAGEAVKRGW 36
>UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1;
Babesia bovis|Rep: Proteasome subunit alpha type 1 -
Babesia bovis
Length = 257
Score = 96.3 bits (229), Expect = 8e-19
Identities = 59/211 (27%), Positives = 99/211 (46%), Gaps = 2/211 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G V + V+ A R+ +L + +F + + I VM+G+ +D++ V
Sbjct: 30 KQGTCCVGIKSQTHIVLCAVRRKSSKLAEYQD--KIFCIGEHIAVVMSGITSDAKMIVNY 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E N ++ YG +I L IA SQ TQ + RP G +++ YDD G +Y+
Sbjct: 88 MRNECLNNKFLYGCDITATKLVSLIAQKSQANTQTSSKRPFGVGLLVAGYDDRTGLHLYE 147
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD--FK 719
T PSG Y A A GA+ YLE+K+ + + D I A+ + + D F
Sbjct: 148 TCPSGNVVEYNATAFGARCQSAKTYLERKIANFEECNIDSLIYHAVKAVKMTIPSDGEFD 207
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAI 812
+ + ++ KD P F++LT E ++ +
Sbjct: 208 VDMVTVCILGKDMP-FKLLTTAETQPYVDKV 237
Score = 37.1 bits (82), Expect = 0.54
Identities = 14/27 (51%), Positives = 21/27 (77%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +SP+GRL+QVEYA++A+ QG
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMEAVKQG 32
>UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1;
Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit,
putative - Trypanosoma cruzi
Length = 179
Score = 93.9 bits (223), Expect = 4e-18
Identities = 53/178 (29%), Positives = 93/178 (52%)
Frame = +3
Query: 279 SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQV 458
+V +F L D +GC +G+ D R V AR ++ Y +PV L R+I+ + Q
Sbjct: 7 TVQKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEPMPVSQLVRQISSLYQE 66
Query: 459 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 638
+TQ+ +RP GCS +L+A D G +Y+ DPSG + ++KA + G + D +LEK+
Sbjct: 67 FTQSGGVRPFGCS-LLVAGADSQGNHLYQVDPSGTFWAWKATSIGKGSTDAKTFLEKRY- 124
Query: 639 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAI 812
+++ +DA+ A+ L + + ++G VS+ F + T ++ +L I
Sbjct: 125 -TNEMEIEDAVHTALLTLKEGFDGTMTAENTQVGRVSEGK--FELFTVDQLKDYLDQI 179
>UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;
Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo
sapiens (Human)
Length = 261
Score = 93.9 bits (223), Expect = 4e-18
Identities = 58/213 (27%), Positives = 108/213 (50%), Gaps = 4/213 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTH-LFALTDRIGCVMTGMIADSRSQV*RARY 374
T + D ++AA+R+ +LLD + ++ L + + C + G+ +D+ R
Sbjct: 33 TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRL 92
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
A + +Y IP L + DI Q YTQ RP G S++ I +D G +Y++DP
Sbjct: 93 IAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDP 152
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 731
SG Y +KA G + + L++ K+ +++ A+ LAI L++ + V S+E +
Sbjct: 153 SGNYGGWKATCIGNNSAAAVSMLKQDYKE-GEMTLKSALALAIKVLNKTMDVSKLSAEKV 211
Query: 732 EIGVVSKDN--PXFRVLTETEIDRHLTAIAEKD 824
EI ++++N RVL + E+++ + E++
Sbjct: 212 EIATLTRENGKTVIRVLKQKEVEQLIKKHEEEE 244
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/27 (70%), Positives = 22/27 (81%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAI 181
S +D TIFSPEGRLYQVEYA++AI
Sbjct: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAI 28
>UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1;
Babesia bovis|Rep: Proteasome alpha 5 subunit, putative
- Babesia bovis
Length = 250
Score = 93.5 bits (222), Expect = 6e-18
Identities = 58/209 (27%), Positives = 103/209 (49%), Gaps = 7/209 (3%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T++A + + A++ +V L++ S+ + + IGC M+G+IAD+R+ +
Sbjct: 32 KLGSTALAIATKEGVIFASEHRVNSPLMESVSLEKIMEIDTHIGCTMSGLIADARTLIDH 91
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADI----SQVY---TQNAEMRPLGCSMMLIAYDDE 524
R E AN ++ Y + + IAD+ S ++ + RP G ++++ D +
Sbjct: 92 GRLECANHRFVYNEPLAIRSCVESIADMALDFSDIFDTRKKKTMSRPFGVALLVGGIDID 151
Query: 525 AGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL 704
GP ++ DPSG YKA A G+ + L+++ R D+S DA L + L QV+
Sbjct: 152 -GPSIWCVDPSGTSIKYKASAIGSAQEGAESVLQERY--RDDMSFRDAELLVLEVLRQVM 208
Query: 705 SVDFKSSEIEIGVVSKDNPXFRVLTETEI 791
+ IE+ + + FR TE EI
Sbjct: 209 KDQMTTKNIEMARIKIHDRQFREYTEDEI 237
Score = 40.7 bits (91), Expect = 0.044
Identities = 17/27 (62%), Positives = 21/27 (77%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR + FSPEGR++QVEYAL AI G
Sbjct: 8 YDRGVNTFSPEGRIFQVEYALGAIKLG 34
>UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4;
n=5; Eukaryota|Rep: Probable proteasome subunit alpha
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 248
Score = 93.5 bits (222), Expect = 6e-18
Identities = 53/180 (29%), Positives = 95/180 (52%), Gaps = 2/180 (1%)
Frame = +3
Query: 222 DAAVVAAQRKVPDRLLDPA-SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYK 398
D V+AA++KV +LL+ S L+ + D + C + G+ AD+ + AR +
Sbjct: 41 DGIVLAAEKKVTSKLLEQEESAEKLYHIGDNMLCAVAGLTADANILINYARRVGQQYLQT 100
Query: 399 YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYK 578
+ E+P L RR+ D+ Q YTQ +RP G S + +D G +++++PSG Y S++
Sbjct: 101 FNEEMPCEQLVRRVCDLKQGYTQYGGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQ 160
Query: 579 AVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKD 755
A + G + + + ++ K D++ D+A +A+ LS+ L S +IE ++KD
Sbjct: 161 ANSIGGNSTSVQSLMRQEYK--DDINLDEASAMAVKFLSKTLDSNSLTHEKIEFATITKD 218
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/32 (68%), Positives = 24/32 (75%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQGWV 196
S +D TIFSPEGRLYQVEYAL+AIN V
Sbjct: 2 SRSYDSRTTIFSPEGRLYQVEYALEAINHAGV 33
>UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia
intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia
ATCC 50803
Length = 244
Score = 93.1 bits (221), Expect = 8e-18
Identities = 54/185 (29%), Positives = 94/185 (50%), Gaps = 2/185 (1%)
Frame = +3
Query: 204 VAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAA 383
+A D V AQ+K+P +L D + ++ + I C ++G+ +D+ + AR +
Sbjct: 34 LAILAQDGIVFVAQKKLPSKLSDQQTSEKIYKIDSHIVCAVSGLTSDANILIDEARTYSQ 93
Query: 384 NWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGY 563
W Y IPV +L + I+D+ Q YT + +RP G S + +D G +Y+TDPSG
Sbjct: 94 KWLAVYDEPIPVEVLVQYISDVKQNYTHHGGLRPYGVSFLFGGWDAHLGFQLYQTDPSGN 153
Query: 564 YCSYKAVAAGAKTVDGNAYLEKKLKKRSD-LSTDDAIQLAISCLSQVLSVDFKSSE-IEI 737
Y ++ A + G + + L++ + S + +A Q A+S L + + SS+ +EI
Sbjct: 154 YSAWVATSIGGSAPEIASALKQNIADSSQKILLKEAQQYAVSALIKTTDITKVSSDKMEI 213
Query: 738 GVVSK 752
V K
Sbjct: 214 LTVVK 218
Score = 36.7 bits (81), Expect = 0.71
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAI 181
FD T+FS +GRL QVEYA+KA+
Sbjct: 4 FDSRTTLFSQDGRLLQVEYAIKAV 27
>UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 251
Score = 92.7 bits (220), Expect = 1e-17
Identities = 60/201 (29%), Positives = 100/201 (49%), Gaps = 2/201 (0%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T++A V A + V +++ + +FA+ ++IGC + G + DS V AR E
Sbjct: 36 TTIAMIYNSGIVFAVDKYVASKMMVAGTNRRVFAIDNQIGCCVAGFVTDSNKIVSIARSE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
+ N+Q YG+ IP+ +L RIA +T +RP GCS++L D + G +Y PS
Sbjct: 96 SLNYQKIYGNPIPIRVLAERIAMYMHNFTLYGSVRPFGCSILLGGLDQDRGVELYCIHPS 155
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD-FKSSEIE 734
G Y A+A G LEK ++K +LS +DA+ A + Q K+ E+E
Sbjct: 156 GSCYKYCAMAVGKGRQFARTDLEKLMEK--NLSEEDALYEAARVIIQSREEGASKNLELE 213
Query: 735 IGVVSKDNP-XFRVLTETEID 794
+ + + F ++ E +I+
Sbjct: 214 MAFIGPGSDFQFSIVPEKQIN 234
Score = 39.1 bits (87), Expect = 0.13
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+G+D ++ FSP+GR++QVEYA KA++ I
Sbjct: 6 SGYDSSVSTFSPDGRVFQVEYANKAVDNSGTTI 38
>UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;
core eudicotyledons|Rep: Proteasome subunit alpha
type-1-A - Arabidopsis thaliana (Mouse-ear cress)
Length = 278
Score = 92.3 bits (219), Expect = 1e-17
Identities = 62/205 (30%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G ++ R V+A K L + +F + D IG + G+ AD R
Sbjct: 30 KQGSAAIGLRSRSHVVLACVNKAQSEL--SSHQRKIFKVDDHIGVAIAGLTADGRVLSRY 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E+ N + Y S +PV L +AD +QV TQ + RP G +L+ DE+G +Y
Sbjct: 88 MRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRPYGVG-LLVGGLDESGAHLYY 146
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD-FKS 722
PSG Y Y+A A G+++ YLE++ + D S +D I+ AI + + L + KS
Sbjct: 147 NCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSSREDLIKDAILAVRETLQGETLKS 206
Query: 723 SEIEIGVVSKDNPXFRVLTETEIDR 797
S + ++ D P F L + I +
Sbjct: 207 SLCTVAILGVDEP-FHFLDQEAIQK 230
Score = 39.9 bits (89), Expect = 0.076
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +T +SP GRL+QVEYA++A+ QG
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQG 32
>UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 288
Score = 91.9 bits (218), Expect = 2e-17
Identities = 59/214 (27%), Positives = 105/214 (49%), Gaps = 2/214 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G V R + V+A ++ RL L+ + + IG ++G+ AD++
Sbjct: 59 KQGTAVVGARNDEIVVLACIKRSTSRLAGYQK--KLYKIDNHIGVAVSGITADAKVICNY 116
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E N+ + Y S IP++ L R+ SQV TQ RP G ++L + DE+GP +++
Sbjct: 117 LRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQEYGRRPFGVGLLLAGF-DESGPHLFE 175
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLS--VDFK 719
T PSG Y ++A G+++ YLEK K+ ++ S D I + L LS +
Sbjct: 176 TCPSGNCFEYYSIAIGSRSQASKTYLEKHFKEFANCSKDQLILHTLRALRSSLSSEQEMN 235
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
+++ ++ + N + L E E ++L I ++
Sbjct: 236 QENVDVAILGR-NDIYNELLEEEKIKYLQIINQE 268
Score = 40.3 bits (90), Expect = 0.058
Identities = 18/44 (40%), Positives = 30/44 (68%)
Frame = +2
Query: 59 LIFDIRINRMARESSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
L+F I I+ M R +D + +SP+GR++Q+EYA++A+ QG
Sbjct: 21 LVFLISISIMYRNQ---YDTDVVTWSPQGRVFQIEYAMEAVKQG 61
>UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9;
Eukaryota|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 271
Score = 91.9 bits (218), Expect = 2e-17
Identities = 53/206 (25%), Positives = 103/206 (50%), Gaps = 6/206 (2%)
Frame = +3
Query: 222 DAAVVAAQRKVPDRLLDPA-SVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYK 398
+ ++ A + + +LLD S+ ++ + I + G+ AD+ + +AR ++ +QY
Sbjct: 51 EGVILGADKAIVSKLLDQGKSLEKIYTIDRHIIAAVAGLTADANILIAQARIDSQRYQYT 110
Query: 399 YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYK 578
YG E PV L +I D Q YTQ +RP G S + YD G +Y++DPSG + +K
Sbjct: 111 YGEEQPVEQLVTQICDRKQSYTQFGGLRPFGVSFLFAGYDKNYGYQLYQSDPSGNFSGWK 170
Query: 579 AVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKD 755
A A G + L+++ + DL+ + + L L++ + +++ E +++ +
Sbjct: 171 ATAIGQNNQTATSLLKQEWNE--DLTLEQGLHLVAKVLTKTMDTTSPTADKFEFSILTHN 228
Query: 756 NP----XFRVLTETEIDRHLTAIAEK 821
N ++L+E EI L + ++
Sbjct: 229 NESNKCSQKILSEKEIGELLEKVQKE 254
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/30 (70%), Positives = 23/30 (76%)
Frame = +2
Query: 95 ESSAGFDRHITIFSPEGRLYQVEYALKAIN 184
E S +D T FSPEGRLYQVEYAL+AIN
Sbjct: 10 EMSRRYDSRTTTFSPEGRLYQVEYALEAIN 39
>UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei rhodesiense
Length = 266
Score = 91.9 bits (218), Expect = 2e-17
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 2/206 (0%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G +V +G D V+ A ++ P L F L + +G ++G++AD R+ R
Sbjct: 32 GSAAVGVKGADYVVLTALKRNPVSGLSSYQ-EKAFKLDEHVGMAISGLVADGRALSRFLR 90
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
E N++Y + S+ P+ +L + Q + Q A RP G +++ YD + GP +Y+T
Sbjct: 91 TECMNYRYMHDSDAPLVMLADIVGAKHQRHIQFAGKRPFGVGLLIAGYDRQ-GPRLYQTV 149
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLS--VDFKSS 725
PSG +KA A G ++ YLE+ + D+ + A+ L S V+
Sbjct: 150 PSGDVFDFKATAMGLRSQAARTYLERHFRGFPACDLDELVMHALRALGAATSGGVELNIK 209
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHL 803
I +V K P F +LTE E ++L
Sbjct: 210 NTTIAIVGKGTP-FTILTEEEARKYL 234
Score = 36.7 bits (81), Expect = 0.71
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D T +SP GRL+QVEYA +A+N G
Sbjct: 6 YDTDTTTWSPTGRLFQVEYANEAVNNG 32
>UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11;
Eukaryota|Rep: Proteasome subunit alpha type-3 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 1/209 (0%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T VA + D V+ ++ VP ++L S + + +G + G +AD+R + RAR E
Sbjct: 36 TLVAIKAKDGVVLGVEKLVPSKMLCSGSNRRVHHIDTHVGVAIAGFLADARQLITRARSE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A N++ YG IP+ +L +RIA + ++T +RP GCS+ + D+ GP ++ +PS
Sbjct: 96 AKNYKSTYGQPIPIKVLSQRIASYNHMHTLYGSVRPFGCSIAITGI-DQYGPQLFLVEPS 154
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIE 734
G Y + G LE+ + S+++ +AI+ + V V K E+E
Sbjct: 155 GSCVGYFGASLGKGKQAAKNELEE--IRFSEMTCREAIKEVSRIIYSVHDEVKDKDFELE 212
Query: 735 IGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
+G +S + + E+ A A++
Sbjct: 213 LGWISTETDNVHQIVPKELHDEGEAYAKQ 241
Score = 37.1 bits (82), Expect = 0.54
Identities = 14/30 (46%), Positives = 25/30 (83%), Gaps = 1/30 (3%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAI-NQG 190
+G+D +++ +SP+G+L+QV+YA KA+ N G
Sbjct: 6 SGYDLYVSTYSPDGKLFQVDYANKAVENSG 35
>UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like,
putative; n=5; Oligohymenophorea|Rep: Proteasome subunit
alpha type 7-like, putative - Tetrahymena thermophila
SB210
Length = 242
Score = 90.6 bits (215), Expect = 4e-17
Identities = 55/184 (29%), Positives = 94/184 (51%), Gaps = 2/184 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
GL S+ RGTD V+ ++ L + ++ + L D +G+ D+R A+
Sbjct: 29 GLCSIGIRGTDCIVMGVEKNPTTILQETRTIRKVQRLDDATCICYSGLTPDARILTNIAK 88
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
E ++ Y +P++ + R IA + Q YTQ + RP G S ++ +D + P +++TD
Sbjct: 89 VECQSYSLNYDDRVPINYIARYIASVQQKYTQKSGARPFGISTLVGGFDSKGQPRLFQTD 148
Query: 552 PSGYYCSYKAVAAG--AKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
PSG +KAVA G KTV N LEK ++ L+ + ++LA L +V+ K+
Sbjct: 149 PSGACTEWKAVALGKHRKTVMEN--LEKNYQEEY-LAEEKCLELACRVLLEVVQSGCKNI 205
Query: 726 EIEI 737
E+ +
Sbjct: 206 ELVV 209
Score = 37.9 bits (84), Expect = 0.31
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+D IT+F G L+QVEYA+ A+NQG I
Sbjct: 3 YDTAITVFGKIGNLFQVEYAMAAVNQGLCSI 33
>UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13;
Eukaryota|Rep: Proteasome subunit alpha type-7 -
Trypanosoma brucei brucei
Length = 247
Score = 90.6 bits (215), Expect = 4e-17
Identities = 55/212 (25%), Positives = 107/212 (50%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R GL +V +G D+ + A ++K +L D + ++ L + I G+ AD+R V
Sbjct: 27 RKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKIYKLDEHIYLASAGLSADARVVVNH 86
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
A+ E ++ Y I V +L R +A + Q TQ++ RP G S ++ +++ P ++K
Sbjct: 87 AQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSSGSRPYGVSTIIGGFNENGQPQLWK 146
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
T+PSG ++ A A G ++EK + ++ D + AI L + +V+ S
Sbjct: 147 TEPSGTSSAWNAAAIGRNDKVVLEFMEKNY--QDGMTRDRCVHFAIKALLE--AVESGSK 202
Query: 726 EIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
IE+ V+ + + +++TE+ R + + ++
Sbjct: 203 NIELLVLERGKAAY--MSDTELHRFVVEVEKE 232
Score = 41.9 bits (94), Expect = 0.019
Identities = 16/27 (59%), Positives = 23/27 (85%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR IT+FSP+G L+QVEYA +A+ +G
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVRKG 29
>UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7;
Aconoidasida|Rep: Proteasome subunit alpha type -
Plasmodium yoelii yoelii
Length = 278
Score = 89.8 bits (213), Expect = 7e-17
Identities = 50/203 (24%), Positives = 104/203 (51%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +VA + ++ AV+A ++K +L +P + L L + +G+ AD+R V +
Sbjct: 64 KKGGCAVAIKSSNFAVLAVEKKNIPKLQNPRTTEKLVKLDEHTCLAFSGLNADARILVNK 123
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E + PV + + +A I Q +T +RP G + ++ + + C+Y+
Sbjct: 124 TRLECQRYYLNMDQPAPVDYIAKYVARIQQKFTHRGGVRPFGIATLITGFKNNKEICIYQ 183
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSS 725
T+PSG Y S+KA A G +LEK ++ ++ ++ + LA+ + +V V+ S
Sbjct: 184 TEPSGIYASWKAQAIGKNAKVVQEFLEKNYQE--NMEKNECLLLALKAIFEV--VELSSK 239
Query: 726 EIEIGVVSKDNPXFRVLTETEID 794
+E+ +++++ + + E E++
Sbjct: 240 NVELALLTEEE--LKYIDEQEVN 260
Score = 41.9 bits (94), Expect = 0.019
Identities = 17/31 (54%), Positives = 24/31 (77%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
S +DR IT+FSP+G L QVE+AL+A+ +G
Sbjct: 36 SKMSYDRAITVFSPDGHLLQVEHALEAVKKG 66
>UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4;
Oryza sativa|Rep: Proteasome subunit alpha type-1 -
Oryza sativa subsp. japonica (Rice)
Length = 270
Score = 88.6 bits (210), Expect = 2e-16
Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 1/190 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G V R AV+AA K L + +F + D G + G+ AD R
Sbjct: 30 KQGSACVGLRSRTHAVLAAANKAASEL--SSHQRKVFRVADHAGVALAGLTADGRVLSRF 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E N + Y + +PV L R+AD +QV TQ + RP G +L+A DE+G +Y
Sbjct: 88 LRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRSWKRPYGVG-LLVAGLDESGAHLYY 146
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD-FKS 722
PSG Y Y+A A G+++ +LE++ + +D + + I+ A+S + + L + S
Sbjct: 147 NCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYTPEQLIKDALSAIKETLQGEKLTS 206
Query: 723 SEIEIGVVSK 752
S + +V +
Sbjct: 207 SNCTVAIVGR 216
Score = 39.9 bits (89), Expect = 0.076
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +T +SP GRL+QVEYA++A+ QG
Sbjct: 6 YDTDVTTWSPAGRLFQVEYAMEAVKQG 32
>UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1;
Anopheles gambiae str. PEST|Rep: Proteasome subunit
alpha type - Anopheles gambiae str. PEST
Length = 278
Score = 87.8 bits (208), Expect = 3e-16
Identities = 43/124 (34%), Positives = 70/124 (56%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T + RG D V+A ++ + +L +P T +F + IG ++GMI D R+ V AR E
Sbjct: 36 TVIGLRGKDGVVLAVEKLITSKLYEPDCGTRIFTIDTSIGMAISGMITDGRAVVDIARQE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
AA+++ + IP+ L R++ YT + +RP G S++L ++ +E GP +Y DPS
Sbjct: 96 AASYRQQNNRPIPLKQLNDRLSSYFHAYTLYSAVRPFGVSVILASWSEEKGPEMYMIDPS 155
Query: 558 GYYC 569
G C
Sbjct: 156 GVSC 159
Score = 36.7 bits (81), Expect = 0.71
Identities = 16/31 (51%), Positives = 23/31 (74%), Gaps = 1/31 (3%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAI-NQGWV 196
G+D + FSP+GR++Q+EYA KA+ N G V
Sbjct: 7 GYDLSASQFSPDGRVFQIEYAAKAVENSGTV 37
>UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1;
Methanocorpusculum labreanum Z|Rep: Proteasome alpha
subunit - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 272
Score = 87.8 bits (208), Expect = 3e-16
Identities = 52/192 (27%), Positives = 90/192 (46%), Gaps = 3/192 (1%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T+V + V+ ++V RLL+P+S+ +F + + IG +G++ D+R V R
Sbjct: 35 KRGTTAVGIKCKTGVVLLVDKRVNSRLLEPSSIEKIFRIDEHIGVASSGLVGDARILVDR 94
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY- 542
AR EA + YG + V L +++ D Q YT RP G ++++ + Y
Sbjct: 95 ARIEAQINRVSYGEPVDVETLAKKLCDHMQSYTLFGGARPYGTALLIAGAESSPTGTKYH 154
Query: 543 --KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDF 716
+TDPSG Y A G E++ K+ S ++A+ L + L F
Sbjct: 155 LFETDPSGTLLEYSATGIGIGRPAVIKLFEQEYKE--TCSAEEAVLLGLKALHTATEGKF 212
Query: 717 KSSEIEIGVVSK 752
+ +EIG+ +
Sbjct: 213 DMNTVEIGIAGE 224
Score = 47.2 bits (107), Expect = 5e-04
Identities = 19/28 (67%), Positives = 25/28 (89%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQG 190
G+DR IT+FSP+GRLYQVEYA +A+ +G
Sbjct: 10 GYDRAITMFSPDGRLYQVEYAREAVKRG 37
>UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7;
Trypanosomatidae|Rep: Proteasome subunit alpha type -
Leishmania major
Length = 285
Score = 87.0 bits (206), Expect = 5e-16
Identities = 51/185 (27%), Positives = 93/185 (50%), Gaps = 8/185 (4%)
Frame = +3
Query: 222 DAAVVAAQRKVPDRLLDPASVTH-------LFALTDRIGCVMTGMIADSRSQV*RARYEA 380
D V+A ++ VP L D ++ ++ + + IGC + G+ +D+ + + AR A
Sbjct: 41 DGVVLAGEKMVPHPLFDSENMQDKNISGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSA 100
Query: 381 ANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSG 560
QY + I + LCR + D Q+YTQ +RP G S +L+ +D G +Y T+PSG
Sbjct: 101 LRHQYTFQEPIAIEDLCRILCDEKQLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSG 160
Query: 561 YYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL-SVDFKSSEIEI 737
Y ++ A A G ++ L+K +++ +D + LA+ L + + + +E+
Sbjct: 161 DYSAWSAYAIGQNDQVAHSLLKKDW--HENMTLEDGMLLALRVLGKTMDTAKIDLGRVEV 218
Query: 738 GVVSK 752
V+ K
Sbjct: 219 AVMRK 223
Score = 42.3 bits (95), Expect = 0.014
Identities = 18/26 (69%), Positives = 21/26 (80%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQ 187
+D T FSPEGRLYQVEYA++AI Q
Sbjct: 5 YDSRTTTFSPEGRLYQVEYAVEAIQQ 30
>UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;
Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo
sapiens (Human)
Length = 241
Score = 87.0 bits (206), Expect = 5e-16
Identities = 49/208 (23%), Positives = 109/208 (52%), Gaps = 5/208 (2%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T++ + ++ +A ++++ L++P+S+ + + IGC M+G+IAD+++ + +
Sbjct: 32 KLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDK 91
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQ-----NAEMRPLGCSMMLIAYDDEAG 530
AR E N + Y + V + + +++++ + + A RP G + +L DE G
Sbjct: 92 ARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVA-LLFGGVDEKG 150
Query: 531 PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV 710
P ++ DPSG + A A G+ + + L++ K ++ +AI+ ++ L QV+
Sbjct: 151 PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSSLIILKQVMEE 208
Query: 711 DFKSSEIEIGVVSKDNPXFRVLTETEID 794
++ IE+ V + F + T+ E++
Sbjct: 209 KLNATNIELATV-QPGQNFHMFTKEELE 235
Score = 41.9 bits (94), Expect = 0.019
Identities = 17/27 (62%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR + FSPEGRL+QVEYA++AI G
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLG 34
>UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome
(prosome macropain) subunit alpha type 4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Proteasome (prosome macropain) subunit alpha type 4 -
Strongylocentrotus purpuratus
Length = 257
Score = 86.6 bits (205), Expect = 7e-16
Identities = 56/213 (26%), Positives = 105/213 (49%), Gaps = 4/213 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTH-LFALTDRIGCVMTGMIADSRSQV*RARY 374
TS+ +D ++AA+R+ +LLD + ++ L + C ++G+ +D+ R
Sbjct: 33 TSLGILASDGVLLAAERRNTHKLLDDVVFSDKIYKLNSDMACSVSGITSDANVLTSELRL 92
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
+ +Y IP L + DI Q YTQ RP G S++ + +D G +Y++DP
Sbjct: 93 AGQRYFLQYQENIPNEQLVSTLCDIKQFYTQAGGKRPFGVSILYMGWDKHYGFQLYQSDP 152
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 731
SG Y +KA G + + L+++ K+ D A+ LA+ LS+ L + + E I
Sbjct: 153 SGNYGGWKATCIGNNSAAAISMLKQEYKE-GDTDLKGALALAVKVLSKTLDMTKVTPEKI 211
Query: 732 EIGVVSKDN--PXFRVLTETEIDRHLTAIAEKD 824
EI +++++ R+L E+ + + E++
Sbjct: 212 EIASLTREDGKTKIRILPVEELQKLIKEHEERE 244
Score = 42.7 bits (96), Expect = 0.011
Identities = 19/27 (70%), Positives = 22/27 (81%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAI 181
S +D TIFSPEGRLYQVEYA++AI
Sbjct: 2 SRRYDSKTTIFSPEGRLYQVEYAMEAI 28
>UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 238
Score = 86.6 bits (205), Expect = 7e-16
Identities = 52/190 (27%), Positives = 94/190 (49%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G T +A + V A +++ +L S ++ L I C TG+ AD+R V +A+
Sbjct: 29 GTTVLAIQAPGIIVAAIEKRDMMKLQKQDSSNNMCLLDKHILCAFTGLPADARVLVEKAQ 88
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
+EA +++ + IP+ + R IA + YTQ+ +RP G + ++ +D P +Y+T
Sbjct: 89 FEAQSYRLTFEDAIPIENIARYIATVQLTYTQSGGVRPFGVTTLICGFDPLDKPHIYETL 148
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG +KA G Y+EK +LS DD ++ I L ++ D + +
Sbjct: 149 PSGILSEWKARGIGRFGHPVQEYIEKYYV--DNLSEDDVKRITIGSLREI--ADCRPKNM 204
Query: 732 EIGVVSKDNP 761
E+ ++ ++P
Sbjct: 205 EVAIMKPNSP 214
Score = 35.1 bits (77), Expect = 2.2
Identities = 14/27 (51%), Positives = 20/27 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR +T FS +GRL+Q+EYA A + G
Sbjct: 3 YDRALTRFSSDGRLFQIEYAAAAAHNG 29
>UniRef50_P21242 Cluster: Proteasome component C1; n=18;
Eukaryota|Rep: Proteasome component C1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 288
Score = 86.6 bits (205), Expect = 7e-16
Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 1/185 (0%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G TS+ + D V A ++ + +LL P + + IGCV +G+I D R V R R
Sbjct: 34 GTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHIGCVYSGLIPDGRHLVNRGR 93
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
EAA+++ Y + IP+ R+ Q +T +RP G S + D+ G +Y +
Sbjct: 94 EEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVS-TIFGGVDKNGAHLYMLE 152
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD-LSTDDAIQLAISCLSQVLSVDFKSSE 728
PSG Y YK A G A LEK + + LS +A++ A + + D K +
Sbjct: 153 PSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII-YLAHEDNKEKD 211
Query: 729 IEIGV 743
E+ +
Sbjct: 212 FELEI 216
Score = 39.9 bits (89), Expect = 0.076
Identities = 16/32 (50%), Positives = 23/32 (71%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
G+D ++FSP+GR +QVEYA+KA+ G I
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSI 38
>UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT
C6 - Encephalitozoon cuniculi
Length = 234
Score = 86.2 bits (204), Expect = 9e-16
Identities = 59/210 (28%), Positives = 98/210 (46%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
GL V + D +V +K+P L+ + T ++++ +TG+ D+ V R +
Sbjct: 30 GLPVVTAKSKDM-IVCVSKKIPQDKLEESEATSFHRVSEKCYVAITGLPGDTDYVVKRIK 88
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
A + +G E+ ILCR AD Q Q++ R + + +D E P +Y+TD
Sbjct: 89 MVANRKAFSFGFEVTPDILCRSFADKVQQLIQSSAERSAAFNASIFGFDKER-PMIYQTD 147
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
SG A AAG K ++EK RSD+ + ++A+ L + + D SE+
Sbjct: 148 MSGISYPCYATAAGEKHGKMTKFIEKNY--RSDIDDKELFEVAVGALLESIGADSGCSEV 205
Query: 732 EIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
E+ + K L+ E+D+ L IAEK
Sbjct: 206 EVAYL-KVGQDLCHLSAKEVDKILQDIAEK 234
>UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:
NEQ521 - Nanoarchaeum equitans
Length = 250
Score = 86.2 bits (204), Expect = 9e-16
Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 3/208 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T++ +V +K+ ++ + P+S+ ++ + D + G+I D R + RAR
Sbjct: 40 TAIGMLYKTGVLVIGDKKIVEKFVIPSSIEKVYIVDDHVIAAPAGIIGDGRVLIERARVI 99
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A ++Y YG I + L + IADI Q YTQ +RP G S++ DD G ++ T+P
Sbjct: 100 AQTYKYFYGHPIDIRGLVKEIADIKQEYTQIGGVRPFGVSIIFAGIDD-TGKHIFVTEPG 158
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVL---SVDFKSSE 728
G + YK G YL K+ + +LS AI+L + L + + + +
Sbjct: 159 GMFWEYKLAVIGEGEQKVLDYLGKEYNE--NLSLKKAIELGLKALYNFYKENNNELTAEK 216
Query: 729 IEIGVVSKDNPXFRVLTETEIDRHLTAI 812
++I V + + + EI++ L I
Sbjct: 217 LDIAYVDEKTKKAKYVDVNEIEKILEKI 244
Score = 38.7 bits (86), Expect = 0.18
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQ 187
G+DR T+FSP+GRL QVEYA + Q
Sbjct: 11 GYDRASTLFSPDGRLLQVEYARTTVKQ 37
>UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1;
Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit -
Trypanosoma brucei
Length = 237
Score = 85.4 bits (202), Expect = 2e-15
Identities = 61/195 (31%), Positives = 97/195 (49%), Gaps = 3/195 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G T+VA D VVA ++ + R+L+ S + A+ + G + G++ D + V RAR
Sbjct: 32 GSTAVAACCKDGVVVAVEKILTSRMLEEGSNNRIHAVDRQAGICVCGVLPDGLAVVSRAR 91
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
EA N + + + I +L RI + VYT + RP GCS+++ +Y D+ GP +Y D
Sbjct: 92 GEAENSRDIFSTPILGSLLASRIGEFMHVYTTHYAYRPFGCSVIIASYADD-GPQLYVAD 150
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQV--LSVDFKSS 725
PSG Y +A G LEK + L+ +A++ + L +V S D K
Sbjct: 151 PSGAVAGYYGIALGKGKTVAKTELEK--LDFATLTCSEAVEKLTNILHEVHDKSKD-KIY 207
Query: 726 EIEIG-VVSKDNPXF 767
E+E+ V K + F
Sbjct: 208 EVEVAWVCDKSDRTF 222
Score = 39.1 bits (87), Expect = 0.13
Identities = 16/31 (51%), Positives = 23/31 (74%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
S +G D+ IFS +GR++QVEYA KA++ G
Sbjct: 2 SGSGHDQSTDIFSADGRVFQVEYACKAVDNG 32
>UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia
intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia
ATCC 50803
Length = 250
Score = 85.4 bits (202), Expect = 2e-15
Identities = 56/216 (25%), Positives = 106/216 (49%), Gaps = 13/216 (6%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G S+ + + V+ + + L+D +++ + ++ +G +G AD R+ + R
Sbjct: 32 GRLSIGIKCANGVVLMCHKAAENPLVDYPTISLVDNVSPSLGITYSGFSADFRNLLNLGR 91
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIA------YDDEA-- 527
+ ++ +PV++L R IA Q YTQ +RP GCS++L ++ EA
Sbjct: 92 KSYEQYWNEFQESMPVNMLARDIASTMQEYTQRGGVRPFGCSVLLAGKSMATEHETEANG 151
Query: 528 ---GPCV-YKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLS 695
P + Y+ D SG Y ++KA A G ++ +LEK+ + +S D I + ++CL
Sbjct: 152 SRINPYILYQVDSSGSYYTWKACANGNQSSQARDFLEKRYNE--SVSISDGILIGLTCLH 209
Query: 696 QVLSVDFKSSEIEIGVVSKD-NPXFRVLTETEIDRH 800
+ + D +EIG++ + FR+L EI+ +
Sbjct: 210 EYVDGDIDGKTVEIGIIGDETGGQFRLLAADEINTY 245
>UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 85.4 bits (202), Expect = 2e-15
Identities = 56/203 (27%), Positives = 104/203 (51%), Gaps = 2/203 (0%)
Frame = +3
Query: 222 DAAVVAAQRKVPDRLLDPASVTHLFALTDR-IGCVMTGMIADSRSQV*RARYEAANWQYK 398
+ ++A +++ LL+ + + DR I V++G AD+ + AR AAN +Y+
Sbjct: 41 EGMILATEKQEVSHLLEHSKHSEKIYPIDRHIFSVVSGHTADANILINYAREAAANHRYQ 100
Query: 399 YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYK 578
+ I + L I D Q TQ RP G + + YD + G ++ TDPSG Y +K
Sbjct: 101 FQDNIALEQLIINICDYKQNKTQVGGQRPFGTAFLFAGYDKKNGFQLFSTDPSGNYAGWK 160
Query: 579 AVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDF-KSSEIEIGVVSKD 755
A A G + N+YL++ K+ +L+ + + +AI L + + + S+IEI V+S+
Sbjct: 161 ATAIGKNNLAANSYLKQDYKE--NLTLEQGLDIAIKALVKTMDTSSPQPSKIEIVVISQQ 218
Query: 756 NPXFRVLTETEIDRHLTAIAEKD 824
V ++T ++ + ++ +K+
Sbjct: 219 GK--EVKSKTYNEKEVLSLLQKN 239
Score = 37.9 bits (84), Expect = 0.31
Identities = 16/29 (55%), Positives = 22/29 (75%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAINQ 187
S +D+ F+P+GRL QVEYA++AINQ
Sbjct: 2 SRRYDQKTNTFTPDGRLKQVEYAIEAINQ 30
>UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4;
Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN -
Encephalitozoon cuniculi
Length = 232
Score = 85.0 bits (201), Expect = 2e-15
Identities = 57/209 (27%), Positives = 105/209 (50%), Gaps = 5/209 (2%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G T++ R + ++ +++K+ L +P SV + + D I +G+ D+++ V R+R
Sbjct: 30 GTTTIGVRTKEFVILCSEKKILSTLQNPKSVVKHYKIYDHIVLGFSGISGDTKTIVKRSR 89
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEM-----RPLGCSMMLIAYDDEAGPC 536
+ + YG I V L + ++ +S + + E RP G S+++ +D E P
Sbjct: 90 DFCISHTHMYGENISVERLLKYLSSLSLRFGEEDEAKMIFRRPFGVSLIIAGFDTE--PR 147
Query: 537 VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDF 716
+Y DPSG Y SYKA A G+ LE + ++ S L D +++ + LS+V+
Sbjct: 148 LYSLDPSGSYISYKAKAIGSGHEVVEGILENEYEEYSGL--DQSLRKVLCTLSKVMKDKI 205
Query: 717 KSSEIEIGVVSKDNPXFRVLTETEIDRHL 803
+E+ VV+++ F LT E+ +L
Sbjct: 206 SKDNVEVVVVTQEESKF--LTPEEVSVYL 232
Score = 36.3 bits (80), Expect = 0.94
Identities = 14/31 (45%), Positives = 22/31 (70%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
F + + +S EGR++Q+EYA+KA+N G I
Sbjct: 4 FKQSVNTYSSEGRIHQIEYAMKAMNLGTTTI 34
>UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT
C3 - Encephalitozoon cuniculi
Length = 233
Score = 84.6 bits (200), Expect = 3e-15
Identities = 56/209 (26%), Positives = 97/209 (46%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G S+ D AV+ + + VP L+ V +F + D IGC +G+ D R QV
Sbjct: 31 GSLSIGASAADGAVLMSFKDVPP-LVIREEVRKVFKICDTIGCTYSGLQPDCRIQVNIGC 89
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
A + YG V + + + Q YTQ + RP G ++M+ A P +Y+ D
Sbjct: 90 QIAEEYYDVYGRYPDVDVFTAHFSSVVQEYTQKSGYRPFG-TLMIFAGPVRGVPRLYQVD 148
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG Y + A+G D ++E++L+ DD I +S + + + ++ ++
Sbjct: 149 PSGSYQTADVCASGVGYSDARKFVERRLE-----GLDDNIVNCVSSIREFAGKEVRAKDL 203
Query: 732 EIGVVSKDNPXFRVLTETEIDRHLTAIAE 818
+IGV K F+ T EI+ ++++
Sbjct: 204 DIGVYYKTENIFKAFTLDEIEEVFDSLSK 232
>UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1;
Rattus norvegicus|Rep: Putative uncharacterized protein
- Rattus norvegicus (Rat)
Length = 99
Score = 83.0 bits (196), Expect = 8e-15
Identities = 46/102 (45%), Positives = 60/102 (58%)
Frame = +3
Query: 324 MTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 503
M G+ ADSR QV RA YEAANW+ K G E PV +LC+RI D+SQVYTQ+ E+R L C M+
Sbjct: 1 MVGITADSRFQVPRAHYEAANWKDKCGYEFPVGVLCKRIDDVSQVYTQDNEVRLL-CCMI 59
Query: 504 LIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 629
+ Y+ + P + C A A K ++LEK
Sbjct: 60 CMGYELKTRPSSVQVGS----CRLYATTAEVKQTQPTSFLEK 97
>UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 233
Score = 82.6 bits (195), Expect = 1e-14
Identities = 59/205 (28%), Positives = 95/205 (46%), Gaps = 1/205 (0%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G+ +V + AV+A P + +F + IG ++G+ AD R R
Sbjct: 32 GMPTVGLKSKTHAVIAGVMHSPSEF--SSHQPKIFKIDQHIGVAISGLTADGRGLCKFLR 89
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
E + + +G+EI V L +A SQ T RP G +++I + GP +++T
Sbjct: 90 NECLHHTFCFGTEIRVADLADTVALQSQKKTSKVGKRPYGVGLLMIGAGVD-GPRLFETC 148
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE- 728
PSG + Y A A G + YLE L + D + D I+ A+ L+ S + S E
Sbjct: 149 PSGQHWEYNAQAIGRRAQAAKTYLETNLNEFPDCTRDQLIRHALRALNDCKSRESDSLEA 208
Query: 729 IEIGVVSKDNPXFRVLTETEIDRHL 803
I +GVV D P F +L E+ +++
Sbjct: 209 IALGVVGIDEP-FTILEGPELQKYI 232
Score = 39.5 bits (88), Expect = 0.10
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D + T FSPEGR+ QVE A+KA+ QG
Sbjct: 6 YDENATTFSPEGRILQVENAMKAVQQG 32
>UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16;
Drosophila|Rep: Proteasome subunit alpha type-7-1B -
Drosophila melanogaster (Fruit fly)
Length = 252
Score = 82.6 bits (195), Expect = 1e-14
Identities = 49/185 (26%), Positives = 91/185 (49%), Gaps = 1/185 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G T + R +A V+ +++ L + V + L D + +G+ AD+R V R
Sbjct: 29 RRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSR 88
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
A+ EA + + + V + R IA + Q YTQ+ RP G S ++ +D++ P +++
Sbjct: 89 AQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQ 148
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTD-DAIQLAISCLSQVLSVDFKS 722
TDPSG + ++A G + Y+EK + ++ + AI+ + L V S++
Sbjct: 149 TDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQ 208
Query: 723 SEIEI 737
E+ +
Sbjct: 209 MEVAV 213
Score = 39.1 bits (87), Expect = 0.13
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR +TI+SP+G L QVEYA +A+ +G
Sbjct: 5 YDRAVTIYSPDGHLLQVEYAQEAVRRG 31
>UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative;
n=2; Theileria|Rep: Proteasome subunit alpha type 1,
putative - Theileria parva
Length = 252
Score = 82.2 bits (194), Expect = 1e-14
Identities = 47/159 (29%), Positives = 79/159 (49%), Gaps = 2/159 (1%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
L+ + + IG M+G+ +D++ + R E + ++ YG +I L +++ SQ TQ
Sbjct: 63 LYKVGEYIGVAMSGITSDAKMIISYMRNECLSNRFLYGCDITASQLVSLVSEKSQANTQV 122
Query: 471 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 650
+ RP G +++ YD+ G +++T PSG + A A GA+ YLE+K+ S+
Sbjct: 123 SSKRPFGVGLLVAGYDETTGLHLFETCPSGNVVEFNATAFGARCQSAKTYLERKIVNFSE 182
Query: 651 LSTDDAIQLAISCLSQVLSVD--FKSSEIEIGVVSKDNP 761
+ I AI L + D F I +GVV K P
Sbjct: 183 SDLNGLIYHAIKALKTTIPNDGEFDVDVISVGVVGKGTP 221
Score = 35.9 bits (79), Expect = 1.2
Identities = 13/27 (48%), Positives = 21/27 (77%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +SP+GRL+QVEYA++++ QG
Sbjct: 6 YDTDCITWSPQGRLFQVEYAMESVKQG 32
>UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2;
Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome
endopeptidase complex - Halorubrum lacusprofundi ATCC
49239
Length = 268
Score = 82.2 bits (194), Expect = 1e-14
Identities = 53/187 (28%), Positives = 89/187 (47%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G SV R D V A + L++ S+ L L D +G G +AD+R + AR
Sbjct: 36 GAPSVGVRTADGVVFVAMSRPSSTLMEAESIEKLHKLDDHLGTASAGHVADARQLIDLAR 95
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
++ + +YG + V L + + D Q TQ RP G + +LI D P ++ D
Sbjct: 96 RQSQGNRLRYGEPVGVETLTKFVTDHIQENTQRGGTRPYGAA-LLIGGIDNGEPRLFAAD 154
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEI 731
PSG +KA G D +LE+ + +LS D ++LAI+ L+ +F+ +++
Sbjct: 155 PSGTPNEWKATVIGGGRSDIQGHLEENWTE--ELSLDAGVELAIAALA-AHDDEFEPTDL 211
Query: 732 EIGVVSK 752
+ V++
Sbjct: 212 AVATVTE 218
Score = 41.9 bits (94), Expect = 0.019
Identities = 16/35 (45%), Positives = 25/35 (71%)
Frame = +2
Query: 86 MARESSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
M +DR ++FSP+GR+YQVEYA +A+++G
Sbjct: 2 MGGNDQQAYDRGTSLFSPDGRIYQVEYAREAVSRG 36
>UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1
- Homo sapiens (Human)
Length = 263
Score = 81.8 bits (193), Expect = 2e-14
Identities = 51/214 (23%), Positives = 101/214 (47%), Gaps = 2/214 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +V + AV+ A ++ L A + + + IG + G+ AD+R
Sbjct: 30 KQGSATVGLKSKTHAVLVALKRAQSELA--AHQKKILHVDNHIGISIAGLTADARLLCNF 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E + ++ + +PV L I +Q+ TQ RP G +++ YDD GP +++
Sbjct: 88 MRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDD-MGPHIFQ 146
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV--DFK 719
T PS Y +A++ GA++ YLE+ + + + + ++ ++ + L + L D
Sbjct: 147 TCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQDLT 206
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
+ + IG+V KD F + + ++ L + E+
Sbjct: 207 TKNVSIGIVGKD-LEFTIYDDDDVSPFLEGLEER 239
Score = 41.5 bits (93), Expect = 0.025
Identities = 13/27 (48%), Positives = 24/27 (88%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +T++SP+GR++Q+EYA++A+ QG
Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQG 32
>UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 266
Score = 79.0 bits (186), Expect = 1e-13
Identities = 39/125 (31%), Positives = 66/125 (52%)
Frame = +3
Query: 204 VAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAA 383
V RG D V+ ++K +L + +V + L D + G+ AD+R + RAR E
Sbjct: 6 VGVRGKDLVVLGVEKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQ 65
Query: 384 NWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGY 563
+ + + V + R +A + Q YTQ+ RP G S +++ +D + P +Y+TDP+G
Sbjct: 66 SHRLTVEDPVTVEYITRFMAQLKQRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGT 125
Query: 564 YCSYK 578
Y S+K
Sbjct: 126 YHSWK 130
Score = 68.1 bits (159), Expect = 3e-10
Identities = 36/121 (29%), Positives = 67/121 (55%)
Frame = +3
Query: 459 YTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 638
YTQ+ RP G S +++ +D + P +Y+TDP+G Y S+KA A G +LEK
Sbjct: 132 YTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEKHYS 191
Query: 639 KRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAE 818
S + ++LA+ L +V+ K+ IE+ V+ + P ++ +E+++++T I +
Sbjct: 192 DEVVESESETVKLAVRALLEVVQSGAKN--IELAVMRRGEP-LKMYEVSEVEKYVTEIEK 248
Query: 819 K 821
+
Sbjct: 249 E 249
>UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep:
Yarrowia lipolytica chromosome C of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 289
Score = 77.0 bits (181), Expect = 5e-13
Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 219 TDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYK 398
T A VVA +R + + + + + +G + G+ D+R R +A + Q
Sbjct: 41 THAVVVALKRNAEEL---GSYQKKIIKVDNHLGVALAGLAPDARVLSNFLRQQAMSSQMV 97
Query: 399 YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYK 578
Y + V IAD +Q TQ RP G +++I + DEAGP +Y+ PSG Y+
Sbjct: 98 YKRPLAVSRAVYAIADKAQGNTQQYGRRPYGVGLLIIGH-DEAGPHLYEFLPSGSALEYR 156
Query: 579 AVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD--FKSSEIEIGVVSK 752
A GA++ YLEKK DLS ++ I ++ L L+ D I V K
Sbjct: 157 GAAIGARSQAARTYLEKKFDTFPDLSLEELIVEGLNALRDTLAQDKELTLKNTSIAYVGK 216
Query: 753 DNPXFRVLTETEI 791
D P F +L + ++
Sbjct: 217 DTP-FTLLDDDKV 228
Score = 38.3 bits (85), Expect = 0.23
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +SP GRL+QVEYAL+AI QG
Sbjct: 5 YDNDSVTYSPTGRLFQVEYALEAIKQG 31
>UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative;
n=5; Plasmodium|Rep: Proteosome subunit alpha type 1,
putative - Plasmodium vivax
Length = 269
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/214 (25%), Positives = 97/214 (45%), Gaps = 2/214 (0%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +VA + D VV +K +L LF + D IG M+G+ +D++
Sbjct: 30 KQGTCAVAIKSKDFVVVCGLKKRISKL--SFHQEKLFKIDDYIGVTMSGITSDAKVLTKY 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E + ++ + + + L +++AD Q TQ + R G +++ Y E P +++
Sbjct: 88 MRNECLSHKFLFDENMNIEKLVKKVADKYQQNTQRSSRRAFGVGLIIAGYFKE--PYIFE 145
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV--DFK 719
T P+G Y Y A++ GA++ YLEK + D S ++ + L LS +
Sbjct: 146 TKPNGSYFEYIALSFGARSHASKTYLEKNVHLFEDSSLEELTIHCLKALRCSLSSENELT 205
Query: 720 SSEIEIGVVSKDNPXFRVLTETEIDRHLTAIAEK 821
I +V KD P + T ++ + AE+
Sbjct: 206 IENTSIAIVGKDKPWQEITTVDLVELLIRVNAEQ 239
Score = 38.3 bits (85), Expect = 0.23
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D +SPEGRLYQVEYA +AI QG
Sbjct: 6 YDTDNITYSPEGRLYQVEYANEAIKQG 32
>UniRef50_Q9BZ93 Cluster: Prosomal P27K protein; n=6; Eutheria|Rep:
Prosomal P27K protein - Homo sapiens (Human)
Length = 58
Score = 76.2 bits (179), Expect = 1e-12
Identities = 33/50 (66%), Positives = 41/50 (82%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGM 335
+ GLTSVA RG D AV+ Q+KVPD+LLD ++VTHLF +T+ IGCVMTGM
Sbjct: 8 QGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGM 57
>UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8;
Eukaryota|Rep: Proteasome subunit alpha type -
Alexandrium fundyense (Dinoflagellate)
Length = 254
Score = 75.8 bits (178), Expect = 1e-12
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T+VA D + A ++ + ++L + +F + G + G ADSR V RAR E
Sbjct: 36 TTVAICCKDGVIFAVEKFLLSKMLVQGTNKRIFPVHRHAGMSIAGFSADSRQIVARARSE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYD-DEAGPCVYKTDP 554
A ++ Y EIP +L R+ YT +RP GCS++L D D P ++ DP
Sbjct: 96 AHQYKNSYNEEIPPELLAERLGLFVHAYTLYWSIRPFGCSVLLGCVDQDTKKPSLFCVDP 155
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD-LSTDDAIQLAISCLSQVLSVDFKSSEI 731
+G Y A G +EK L ++ L+ +A+ L +V K E+
Sbjct: 156 AGMVFKYSGTAIGKGKQAAKTEIEKLLANGTESLTCAEALVHVAKILHKVHDEKDKDFEL 215
Query: 732 E 734
E
Sbjct: 216 E 216
Score = 42.7 bits (96), Expect = 0.011
Identities = 21/38 (55%), Positives = 28/38 (73%), Gaps = 2/38 (5%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAI-NQG-WVDIC 205
+ AG+D +T FSP+GR++QVEYA KA+ N G V IC
Sbjct: 4 TGAGYDLSVTTFSPDGRVFQVEYAQKAVENSGTTVAIC 41
>UniRef50_A6R382 Cluster: Proteasome component C1; n=3;
Pezizomycotina|Rep: Proteasome component C1 -
Ajellomyces capsulatus NAm1
Length = 426
Score = 75.8 bits (178), Expect = 1e-12
Identities = 51/172 (29%), Positives = 75/172 (43%), Gaps = 26/172 (15%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G TS+ R D V+A ++ + +LL P + + + IG V +G++ D R V RAR
Sbjct: 163 GGTSIGIRCKDGVVLAVEKIISSKLLKPGANKRIATVDRHIGIVSSGLLPDGRHFVSRAR 222
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDE--------- 524
EA NW+ Y I H+L R+ +Q YT + +RP G + ++ +D E
Sbjct: 223 DEADNWRITYKGPISTHVLASRLGGYAQAYTLYSSVRPFGVTSIIGGWDSELELPVDGEV 282
Query: 525 -----------------AGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEK 629
GP +Y +PSG Y Y A G A LEK
Sbjct: 283 GAGPKSGAGGKVASAKAGGPGLYMIEPSGLYWGYYGAATGKGRQAAKAELEK 334
Score = 40.3 bits (90), Expect = 0.058
Identities = 17/32 (53%), Positives = 23/32 (71%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
G+D +IFSP+GR +QVEYA+KA+ G I
Sbjct: 136 GYDLSNSIFSPDGRNFQVEYAVKAVENGGTSI 167
>UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Aspergillus terreus (strain NIH 2624)
Length = 311
Score = 75.4 bits (177), Expect = 2e-12
Identities = 44/144 (30%), Positives = 70/144 (48%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G T++ R D V+A ++ + +LL P + + + +G V +G++ D R V RAR
Sbjct: 34 GGTAIGIRCKDGVVLAVEKIITSKLLKPGANKRIATVDRHVGIVSSGLVPDGRHFVSRAR 93
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
EA++W+ Y S IPV L R+ Q YT + +RP G + ++ +D EA V
Sbjct: 94 DEASSWRGVYKSPIPVSALSNRLGSYVQAYTLYSSVRPFGITAIIGGWDSEAELAVDGQV 153
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYL 623
SG GAK+ Y+
Sbjct: 154 GSGPTSGAGGKVEGAKSGGPGLYM 177
Score = 39.1 bits (87), Expect = 0.13
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQG 190
G+D ++FSP+GR +QVEYA+KA+ G
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENG 34
>UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4;
Saccharomycetales|Rep: Proteasome component Y7 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 178
Score = 75.4 bits (177), Expect = 2e-12
Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 2/158 (1%)
Frame = +3
Query: 327 TGMIADSRSQV*RARYEA-ANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 503
+GM D R V +AR A N++ Y PV I+ + IA + Q TQ+ +RP G S++
Sbjct: 4 SGMGPDFRVLVDKARKLAQTNYKLIYNEYPPVRIMVQEIAKVMQESTQSGGIRPFGVSLL 63
Query: 504 LIAYDDEAGPC-VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLA 680
+ YD+ +Y+ DPSG Y +KA A G + +LEK+ + +L +DAI +A
Sbjct: 64 VGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEKRWNE--NLQLEDAIHVA 121
Query: 681 ISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEID 794
+ L + + + ++I V+S T T ++
Sbjct: 122 LLALKESVDGELIGENLDIAVISDPQQQLLGFTGTNLE 159
>UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 244
Score = 74.9 bits (176), Expect = 2e-12
Identities = 45/167 (26%), Positives = 82/167 (49%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T + R D ++ A++K+ +L+ S ++ + IG ++ G I D R+ V RAR E
Sbjct: 30 TILGVRCKDGVILGAEKKLQTKLMVEDSDRRIYNIQKNIGMIVGGRIPDGRNVVHRARKE 89
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A ++ + I IL R +T RP GCS+++ +YD G ++++D +
Sbjct: 90 AQEYEKYFSMPISGRILSERTGQYLHAHTLYGAYRPFGCSVIISSYDPIDGLQLHQSDNA 149
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQ 698
GY Y A A G + A+ + + DL+ ++A+ I L++
Sbjct: 150 GYCLGYYACAQGQGKQEVMAHFGR--RNFRDLTCEEALPYVILALNK 194
>UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus lucimarinus CCE9901
Length = 236
Score = 74.1 bits (174), Expect = 4e-12
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 2/189 (1%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T VA AV+AA ++ +L + +FA+ R+G ++G+ D V
Sbjct: 30 KQGSTVVACGNKKCAVLAALKRKQSKL--SSMQEKIFAINTRVGVAVSGLSTDGAKLVKL 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R E+ ++ YG L + Q+ + + RP G ++L+ ++ G +++
Sbjct: 88 LREESTREEFVYGRSACPGRLAAAASKSLQISMRKSSGRPCGVGLVLVGSSEQLGCQIFQ 147
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCL--SQVLSVDFK 719
T PSG A G ++ YLEK ++ S D+ I +A+ L S V + D
Sbjct: 148 TCPSGEVHQMSCTAIGGRSQSARTYLEKNMEALETASVDEMIMIALRALNESNVDASDLT 207
Query: 720 SSEIEIGVV 746
S + E+ +V
Sbjct: 208 SDKCEVAIV 216
Score = 39.1 bits (87), Expect = 0.13
Identities = 17/34 (50%), Positives = 26/34 (76%), Gaps = 1/34 (2%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG-WVDICG 208
+D+ + +SP+GRL+QVEYA++A+ QG V CG
Sbjct: 6 YDQDMLTWSPQGRLHQVEYAMEAVKQGSTVVACG 39
>UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12;
Magnoliophyta|Rep: Proteasome subunit alpha type-3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 249
Score = 73.7 bits (173), Expect = 5e-12
Identities = 42/144 (29%), Positives = 69/144 (47%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T V + D V+ ++ + +++ P S + ++ G + G+ AD R V RA+ E
Sbjct: 36 TVVGIKCKDGIVMGVEKLIASKMMLPGSNRRIHSVHRHAGMAVAGLAADGRQIVARAKSE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A +++ YG +PV L R+A + T +RP GC ++L YD + GP +Y +PS
Sbjct: 96 ARSYESVYGDAVPVKELSERVASYVHLCTLYWWLRPFGCGVILGGYDRD-GPQLYMIEPS 154
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEK 629
G Y A G +EK
Sbjct: 155 GISYRYFGAAIGKGKQAAKTEIEK 178
Score = 40.7 bits (91), Expect = 0.044
Identities = 17/31 (54%), Positives = 24/31 (77%), Gaps = 1/31 (3%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAI-NQGWV 196
G+D +T FSP+GR++Q+EYA KA+ N G V
Sbjct: 7 GYDLSVTTFSPDGRVFQIEYAAKAVDNSGTV 37
>UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family
protein; n=5; Oligohymenophorea|Rep: Proteasome A-type
and B-type family protein - Tetrahymena thermophila
SB210
Length = 267
Score = 73.3 bits (172), Expect = 7e-12
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G ++ R AV+ AQ++ +L +F + D+IG + G+ AD+R R
Sbjct: 49 GSITIGLRSQKFAVLVAQKRSNSKL--SGYQEKIFQVDDKIGMGVAGITADARVICKYMR 106
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTD 551
E N +Y YGS+ P L +I++ SQ TQ RP G ++IA + + GP +++T
Sbjct: 107 TECLNHKYVYGSQHPAQRLVIKISEKSQHKTQTYGKRPYGVGTLIIAQESD-GPKLFQTL 165
Query: 552 PSGYYCSYKAVAAGAKTVDGNAYLEKKL---KKRSDLST 659
PSG + + + G+++ YLE L K +DL+T
Sbjct: 166 PSGDFYEFYGQSIGSRSQAAKTYLENNLELFKDCNDLNT 204
Score = 34.7 bits (76), Expect = 2.9
Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Frame = +2
Query: 59 LIFDIRINRMARESSAG-FDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+I +I+ N+ S+ +D + +S G+L QV+YA KAI+QG + I
Sbjct: 5 VINNIKSNKQQMSSNINLYDTDCSTWSTNGKLLQVDYATKAIDQGSITI 53
>UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1;
Homo sapiens|Rep: Proteasome alpha 6 subunit variant -
Homo sapiens (Human)
Length = 80
Score = 72.9 bits (171), Expect = 9e-12
Identities = 29/61 (47%), Positives = 44/61 (72%)
Frame = +3
Query: 498 MMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQL 677
M+LI D+E GP VYK DP+GYYC +KA AAG K + ++LEKK+KK+ D + + +++
Sbjct: 9 MILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVEV 68
Query: 678 A 680
+
Sbjct: 69 S 69
>UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3;
Basidiomycota|Rep: Proteasome subunit alpha type -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 299
Score = 71.7 bits (168), Expect = 2e-11
Identities = 44/151 (29%), Positives = 69/151 (45%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
L + D +G + G+ +D+R R +A + YG PV L + IAD +Q TQ
Sbjct: 63 LIRIDDHVGVAIAGLTSDARVLSNYMRQKAMQSRMTYGRATPVARLVQSIADRAQTNTQE 122
Query: 471 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 650
RP G ++I DE GP +++ P+G Y A + GA++ YLEK +
Sbjct: 123 YGRRPYGVGFLVIG-KDETGPHLFEFSPAGTAFEYYAHSIGARSQSAKTYLEKNYHLFPN 181
Query: 651 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 743
S ++ I +S L L D S + +
Sbjct: 182 ASLEELINHGLSALHDTLQQDKHLSSLNTSI 212
Score = 40.3 bits (90), Expect = 0.058
Identities = 16/27 (59%), Positives = 22/27 (81%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D T FSP+G+L+QVEYAL+A+ QG
Sbjct: 6 YDSDNTTFSPQGKLFQVEYALEAVKQG 32
>UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia
intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia
ATCC 50803
Length = 255
Score = 71.3 bits (167), Expect = 3e-11
Identities = 58/210 (27%), Positives = 99/210 (47%), Gaps = 6/210 (2%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G SV DA V+ A R+ L + LF + IG ++G+ AD+ + R
Sbjct: 29 GSPSVGLASKDAVVLVAVRRQTTPL--SSFQDKLFEVDKHIGICISGIYADAYKMLRLLR 86
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYD---DEAGPCVY 542
E + Y Y + PV L ++A+ +Q TQ RP G S+++ D ++ P +Y
Sbjct: 87 DECTEYTYVYDTPHPVGPLVAKLAEDAQARTQFWGYRPYGASLLIGGIDTRNNKQTPRLY 146
Query: 543 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKS 722
P+ + Y+AV+ G + N +L+ + + + S + I LA+ L + D +
Sbjct: 147 VLSPNAVFKEYRAVSLGMGSQTINTHLKSHVDEYENASVERLIALALDSLGTGVK-DCRP 205
Query: 723 SE--IEIGVVSK-DNPXFRVLTETEIDRHL 803
SE + IGV+ + R+LT+ EI H+
Sbjct: 206 SEKNLSIGVLDRTTGGVLRILTKEEILPHI 235
>UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 247
Score = 70.5 bits (165), Expect = 5e-11
Identities = 38/132 (28%), Positives = 68/132 (51%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T+++ + D V ++ + ++++ +S +F + +G G + D+R V +A E
Sbjct: 36 TALSIKCIDGVVFGVEKLIISKMIEKSSNKRIFNVGTHVGITCAGFLPDARKLVKKANEE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A +++ YG IPV +L +IA Q +T +RP GCS +LI D+ G ++ +PS
Sbjct: 96 AESFKENYGMNIPVKVLAEKIAMYMQNHTLYGSLRPFGCS-LLIGGVDQHGYSLHYIEPS 154
Query: 558 GYYCSYKAVAAG 593
G Y A G
Sbjct: 155 GTTYGYFANGIG 166
Score = 35.9 bits (79), Expect = 1.2
Identities = 12/26 (46%), Positives = 21/26 (80%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAI 181
+G+D T FSP+G+++Q++YA KA+
Sbjct: 6 SGYDDSCTTFSPDGKVFQIDYATKAV 31
>UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA,
RIKEN full-length enriched library, clone:C920013M15
product:proteasome (prosome, macropain) subunit, alpha
type 3, full insert sequence; n=13; Euteleostomi|Rep: 2
days neonate thymus thymic cells cDNA, RIKEN full-length
enriched library, clone:C920013M15 product:proteasome
(prosome, macropain) subunit, alpha type 3, full insert
sequence - Mus musculus (Mouse)
Length = 180
Score = 68.1 bits (159), Expect = 3e-10
Identities = 45/144 (31%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Frame = +3
Query: 324 MTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMM 503
+ G++AD+RS AR EA+N++ +G IP+ L R+A YT + +RP GCS M
Sbjct: 3 VAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFM 62
Query: 504 LIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAI 683
L +Y G +Y DPSG Y A G +EK K +++ D ++
Sbjct: 63 LGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDVVKEVA 120
Query: 684 SCLSQVL-SVDFKSSEIEIGVVSK 752
+ V V K+ E+E+ V +
Sbjct: 121 KIIYIVHDEVKDKAFELELSWVGE 144
>UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Chaetomium globosum (Soil fungus)
Length = 267
Score = 67.7 bits (158), Expect = 3e-10
Identities = 38/141 (26%), Positives = 68/141 (48%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
LF + + +G + G+ +D+R + + + +G +PV L I +Q+ TQ+
Sbjct: 63 LFPIDEHVGIAIAGLTSDARVLSNFMKQQCLGHRLTFGRSMPVRTLVEIIGSKAQINTQH 122
Query: 471 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 650
RP G +++ DD GP +++ PSG A A GA++ YLEK + K +D
Sbjct: 123 YGKRPYGVGLLVAGVDDH-GPHLFEFQPSGMTEEMVAFAIGARSQMARTYLEKNIDKFAD 181
Query: 651 LSTDDAIQLAISCLSQVLSVD 713
++ I+ + L + L D
Sbjct: 182 CDREELIRHGLRALKESLVQD 202
Score = 37.9 bits (84), Expect = 0.31
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQGWV 196
+D FSP+GR++QVEYA +A+ QG V
Sbjct: 6 YDNDSVTFSPQGRIFQVEYAAEAVKQGSV 34
>UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2;
Caenorhabditis|Rep: Proteasome subunit alpha type-3 -
Caenorhabditis elegans
Length = 250
Score = 66.1 bits (154), Expect = 1e-09
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 1/186 (0%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T +A RG + VV A + + +L + +F + D +G + G D + A E
Sbjct: 36 TMIAIRGKNGVVVVADKLISSKLYTDNANPRMFNVNDNVGVAVAGNYPDGFALKNYAYGE 95
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
A W Y +P+ + +A+ ++T RP G ++++ + G ++ +PS
Sbjct: 96 AMKWLKDYREPMPIQNIANSVAEYIHIHTLGIS-RPFGAGAFFMSWNKQTGGRLFLVEPS 154
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD-FKSSEIE 734
G YKA A G A +EK K +L + ++ A + V + K+ +IE
Sbjct: 155 GLNYEYKAWAVGKHRQAAKAEIEK--LKIEELDVNQLVKEAARIIMVVRDENKDKNVQIE 212
Query: 735 IGVVSK 752
+G V +
Sbjct: 213 MGWVGE 218
Score = 36.7 bits (81), Expect = 0.71
Identities = 14/26 (53%), Positives = 21/26 (80%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAIN 184
G+D + FSP+GR++QVEYA KA++
Sbjct: 7 GYDLAASTFSPDGRIFQVEYAQKAVD 32
>UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 64.1 bits (149), Expect = 4e-09
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 2/181 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T + + D ++A +++ RLL+ + ++ + + G + G + D R+ + RA+ E
Sbjct: 34 TVIGVKCKDGVILAGEKQKFSRLLEDNTNKRIYNIDTQTGMAICGKLPDGRNILQRAKAE 93
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
++ +Q Y + ++L R+A YT + RP G + + +Y+ G ++ +PS
Sbjct: 94 SSQYQDMYAIPVSANVLSDRVAQYVHAYTMYSGARPFGSATFIASYNTFDGYELFMIEPS 153
Query: 558 GYYCSYKAVAAGAKTVDGNAYLEKKLKKRS--DLSTDDAIQLAISCLSQVLSVDFKSSEI 731
G +Y A G G A + + ++R+ DL+ +A+ + I+ + + +FK +
Sbjct: 154 GNKYAYHACTHG----KGRAVCKSEFERRNFKDLTCQEAL-VYIAKMLILAHEEFKEKKY 208
Query: 732 E 734
E
Sbjct: 209 E 209
Score = 35.1 bits (77), Expect = 2.2
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAI 181
S + +D + +S EGR+YQVEYA KA+
Sbjct: 2 SGSMYDLSVATYSQEGRIYQVEYATKAV 29
>UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 240
Score = 63.3 bits (147), Expect = 7e-09
Identities = 44/172 (25%), Positives = 77/172 (44%)
Frame = +3
Query: 222 DAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKY 401
D ++AA++ + LL P +F + D I C G D S V ++R A + +
Sbjct: 44 DGILLAAEKNLTSTLLTPGGNPRIFWINDSIACATIGHRPDCYSIVEQSRNRAETFTSNF 103
Query: 402 GSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKA 581
G +I V L ++ + RP GC+++ +Y D+A +Y +PSG + Y A
Sbjct: 104 GIKITVPQLASEVSQQFHLAHYYQAYRPFGCTVIFASYKDDA---LYAIEPSGAFYGYFA 160
Query: 582 VAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 737
G + A L+K K +++ +A+ + + FK EIE+
Sbjct: 161 SCFGKNSNLARAELQKTEWK--NITVREAVPEVARIIKSLHESQFKKWEIEM 210
Score = 35.5 bits (78), Expect = 1.6
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAINQ 187
+ +G+D + FSP+GR +QVEYA KA+ +
Sbjct: 4 AGSGYDFNPITFSPDGRQFQVEYATKAVEK 33
>UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia
intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia
ATCC 50803
Length = 292
Score = 62.9 bits (146), Expect = 9e-09
Identities = 44/154 (28%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Frame = +3
Query: 204 VAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAA 383
V R + +A Q+ + D +L+ S + + D I + G+ D V +AR A
Sbjct: 58 VGIRTSGGVALAVQKNIHD-ILEIDSAPCFYQIEDSIVIAVAGLQPDGMVLVSKAREVAE 116
Query: 384 NWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG---PCVYKT-- 548
+++ Y +P +L I+ Q+YT E+RP GCS+++ YD A P KT
Sbjct: 117 SYRENYSRIVPTGVLANSISGYMQLYTHYGEVRPFGCSLLIAGYDSIASADEPTTLKTKY 176
Query: 549 -----DPSGYYCSYKAVAAGAKTVDGNAYLEKKL 635
PSG + A AAG T LE +
Sbjct: 177 SLYLLQPSGDITNCFATAAGRHTSQAKVELENHM 210
Score = 35.9 bits (79), Expect = 1.2
Identities = 13/28 (46%), Positives = 22/28 (78%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQ 187
+G+D +SP+G+++QV+YALKA+ Q
Sbjct: 26 SGYDVSCGSYSPDGKIFQVDYALKAVEQ 53
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 62.5 bits (145), Expect = 1e-08
Identities = 44/178 (24%), Positives = 86/178 (48%), Gaps = 1/178 (0%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
T + + + V+A ++++ D + + + +T +G G++ D++ + R
Sbjct: 19 TVLGIKAVNGVVIAGEKRLTYDGYVLSKNTRKVHPITKHVGIGFAGLVGDAQFIIRALRM 78
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
EA N++ + G EI V R +A I + + ++ PL +++ +D E GP +Y DP
Sbjct: 79 EAENYELQLGREIRV----RGLAKILSLILYSYKLAPLMTEVVVGGFD-EKGPQIYVLDP 133
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
G K VA G+ +EK+ R D+ D+A +LA+S + + + D S +
Sbjct: 134 VGSLIEDKYVALGSGGPIALGIIEKEY--REDIDVDEAEKLAVSAIREAIERDAVSGD 189
>UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus tauri
Length = 262
Score = 62.1 bits (144), Expect = 2e-08
Identities = 43/162 (26%), Positives = 74/162 (45%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
AG +V + D V+A ++ VP +L P + A+ G +G D + RA
Sbjct: 93 AGGLTVGVKCVDGVVIACEKLVPSKLHKPGTNRRTRAVARHAGVGGSGYTPDLAAVADRA 152
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
R E AN++ YG IP +L R+A ++T +RP GCS +L D + G +Y
Sbjct: 153 RAECANYKSFYGDAIPGKVLAERMAHYYHLFTLYWSVRPFGCSTLLGCKDFD-GYHLYLV 211
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQ 674
+ +G + G +EK K ++++ +A++
Sbjct: 212 EQNGECAKMRGACIGKGKNAAKTEVEK--LKLNEITCAEAVK 251
Score = 39.1 bits (87), Expect = 0.13
Identities = 15/33 (45%), Positives = 25/33 (75%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQGWVDI 202
+G+D T +SP+GR++QVEYA KA++ G + +
Sbjct: 66 SGYDLSTTTYSPDGRVFQVEYAGKAVDAGGLTV 98
>UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative;
n=6; Plasmodium|Rep: 20S proteasome alpha subunit G,
putative - Plasmodium vivax
Length = 253
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/132 (23%), Positives = 67/132 (50%)
Frame = +3
Query: 258 DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRR 437
++++ +S + + + + + G+ D+R+ + RA+YEA ++ + + IP+HIL R
Sbjct: 58 NKMIKHSSYSRIHHINNNVIVTYAGLDGDARNIIDRAKYEANSYYLNFHTNIPLHILANR 117
Query: 438 IADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNA 617
++ +T +RP S++L ++D++ +Y +P+G Y V G
Sbjct: 118 VSLYLHSFTLYWHLRPFASSIILASFDEKEKGEIYCVEPNGACYKYSGVVIGKNKEMFKT 177
Query: 618 YLEKKLKKRSDL 653
+EK+ K D+
Sbjct: 178 EIEKRNYKDVDV 189
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/28 (67%), Positives = 23/28 (82%)
Frame = +2
Query: 101 SAGFDRHITIFSPEGRLYQVEYALKAIN 184
SAG+D ++ FSP+GRLYQVEY KAIN
Sbjct: 5 SAGYDLSVSTFSPDGRLYQVEYIYKAIN 32
>UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia
theta|Rep: 26S proteasome SU A5 - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 61.3 bits (142), Expect = 3e-08
Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 5/212 (2%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RAR 371
G TS + D + ++RK + LD + ++ L GC ++G+I+DSR + R
Sbjct: 26 GSTSCGIKTKDFIFILSERK-KKKSLDYLNDQKIYVLDKNKGCCVSGLISDSRKIIDNVR 84
Query: 372 YEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEM-----RPLGCSMMLIAYDDEAGPC 536
N + S + I ++ Y N ++ RPLG S +L ++
Sbjct: 85 IYCENKYFLINSYPSIEECSNLINNLITSYNTNNDVNKISPRPLGTSFLLFGKSNKKLEL 144
Query: 537 VYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDF 716
+ K DPSG Y K +A G + D L++ RS++ +A LA L +
Sbjct: 145 I-KVDPSGRYIKDKILAIGEGSKDVLIILQEGY--RSNMKKIEAKTLAFKTLRAISESIL 201
Query: 717 KSSEIEIGVVSKDNPXFRVLTETEIDRHLTAI 812
+E +S+ N R+L + EI++ L I
Sbjct: 202 NEKNVEAAQISESN-TLRILFKEEINQILKLI 232
>UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 200
Score = 59.3 bits (137), Expect = 1e-07
Identities = 50/190 (26%), Positives = 87/190 (45%), Gaps = 2/190 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRLLDPASVT-HLFALTDRIGCVMTGMIADSRSQV*RA 368
G T+V G D V+AA R+ T + + I + G + D++ V R
Sbjct: 12 GTTTVGLVGKDFVVLAADRRATAGYFIANKQTWKIVEIDSHIAATIAGTVGDAQQLVDRL 71
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
R EA ++ G +PV + +A ++ + + RP+ MLI D GP ++
Sbjct: 72 RVEARYYKTITGDSMPV----KSVATLASLIL--FQYRPILSVQMLIGGVDSDGPSLFSV 125
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
D G K A G+ + + LE + R DLS ++A+ LA+ ++ L+ D S E
Sbjct: 126 DWLGTVTREKYTATGSGSPYAVSLLEHEY--REDLSLEEAVNLAVKAVNIALARDPGSGE 183
Query: 729 -IEIGVVSKD 755
++I ++K+
Sbjct: 184 GVDIATITKE 193
>UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1;
Guillardia theta|Rep: Similar to proteasome A-type
submit - Guillardia theta (Cryptomonas phi)
Length = 233
Score = 58.4 bits (135), Expect = 2e-07
Identities = 40/167 (23%), Positives = 83/167 (49%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
+F + I +G+ +D + +AR ++Q+KYG +I L + ++ Q +T +
Sbjct: 61 VFIINKYIILSASGLKSDIIIVISKARSICRDFQHKYGHQISTASLSKDLSSFLQNFTSS 120
Query: 471 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 650
+ RPLG S+ ++ D + GP +++ + SG + G + D Y+ + + S+
Sbjct: 121 SGFRPLGVSLNILGIDKD-GPELFEINTSGEINDVNFSSIGKSSKDIKEYI--RARWCSN 177
Query: 651 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEI 791
L T ++L I+CL+ V K EI I ++ P ++ ++ ++
Sbjct: 178 LETKTLLKLVINCLNYYNLVTSKLVEIVIATIN-TQPKIKIFSKEDL 223
>UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 306
Score = 58.4 bits (135), Expect = 2e-07
Identities = 47/194 (24%), Positives = 87/194 (44%), Gaps = 2/194 (1%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G +V R V+ A ++ D L + + D +G + G+ D+R
Sbjct: 103 KQGSATVGLRSNKYVVLVALKRNADEL--SSYQKKIIKCDDHMGLSLAGLAPDARVLSNF 160
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
R + Q Y ++ V + ++D +Q TQ+ RP G ++L YD+ +G + +
Sbjct: 161 LRQQCNYSQLVYARDLSVVKAGQLLSDKAQKNTQSYGGRPYGVGLLLAGYDN-SGAHLLE 219
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDA-IQLAISCLSQVLSVDFKS 722
PSG A GA++ YLE+ +++ ++ DA I+ + L L + S
Sbjct: 220 FQPSGNTLELYGAAIGARSQGAKTYLERVMEEYLEIEDADALIKHGVEALKHSLKDETLS 279
Query: 723 SE-IEIGVVSKDNP 761
++ + I +V KD P
Sbjct: 280 TKNLSIAIVGKDMP 293
Score = 39.1 bits (87), Expect = 0.13
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+D FSP GRL+QVEYAL+AI QG
Sbjct: 79 YDGDTVTFSPTGRLFQVEYALEAIKQG 105
>UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia
theta|Rep: 26S proteasome SU - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 56.4 bits (130), Expect = 8e-07
Identities = 30/120 (25%), Positives = 59/120 (49%)
Frame = +3
Query: 294 FALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNA 473
FAL I C+ +G I D+ + + + A ++ + +P+ + ++DI TQ
Sbjct: 58 FALEKNIICIASGNIPDANTILFYLKSFADEYKLMFQETVPIEKIVGYLSDIMHKPTQMI 117
Query: 474 EMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDL 653
RPLG S ++ +D+ G ++K DPSG + ++A + G + +E+ + +L
Sbjct: 118 YQRPLGVSFIIGGWDEFRGFQLFKIDPSGNFSGWRATSIGFNNILNQTLIEENYHNKINL 177
>UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative;
n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3,
putative - Theileria parva
Length = 267
Score = 56.0 bits (129), Expect = 1e-06
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 16/207 (7%)
Frame = +3
Query: 222 DAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYK 398
D+ AQ P +L +FA+ +R+G + G++ D++ V RA+ E ++ +
Sbjct: 51 DSLACGAQDDSPYANVLQAKPAWRVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKE 110
Query: 399 YGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT---------- 548
YG++ PV ++ R+A YT +RP G S++L ++ Y
Sbjct: 111 YGTKAPVRVIAERVALFVHAYTLYWHVRPFGVSILLAGTNENNSRTTYSVLQLFTSYELY 170
Query: 549 --DPSGYYCSYKAVAAGAKTVDGNAYLEK-KLK-KRSDLSTDDAIQLAISCLSQVLSVDF 716
+ SG Y +A G LEK LK K+ S D + C +
Sbjct: 171 CIEGSGACYKYGGMAIGKGKHIAKTELEKLNLKEKKCKESLSDICYIISQCRDE---GSL 227
Query: 717 KSSEIEIGVVSKD-NPXFRVLTETEID 794
K+S++++ + D N F+++ + I+
Sbjct: 228 KTSDVQMAWICPDSNNTFQIIPQELIN 254
Score = 40.3 bits (90), Expect = 0.058
Identities = 15/27 (55%), Positives = 23/27 (85%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAIN 184
AG+D ++ FSP+GR++QVEYA KA++
Sbjct: 6 AGYDLSVSTFSPDGRVFQVEYATKAVD 32
>UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE
SUBUNIT C9 - Encephalitozoon cuniculi
Length = 232
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/140 (28%), Positives = 62/140 (44%)
Frame = +3
Query: 174 KQ*TRAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRS 353
K +RAG T + +D V+ K P + ++ L+D I CV+ G+ D+
Sbjct: 25 KNVSRAG-TIIGYVCSDGVVLMGVNKEPTN----GPMEKIYQLSDSIYCVLCGLFGDAME 79
Query: 354 QV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGP 533
AR +A ++G E P+ LC+ + Q +TQ A RP G S + D
Sbjct: 80 LKRYARIKAQEVLERFGVECPLTTLCKFVGQRKQAFTQYAGTRPFGVSFLYAGVID-GKY 138
Query: 534 CVYKTDPSGYYCSYKAVAAG 593
+ TDPSG +K + G
Sbjct: 139 ALMSTDPSGTSNRWKGMCYG 158
>UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1;
Medicago truncatula|Rep: 20S proteasome, A and B
subunits - Medicago truncatula (Barrel medic)
Length = 336
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/208 (24%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKV--PDRLLDPASVTHLFALTDRIGCV-----MTGMIADSR 350
G T++ + + V+AA++++ P L P V ++ + + I C+ +TG IA++
Sbjct: 136 GTTAIGLKFKEGVVLAAEKRITWPTSPLYPGIVQNIMEIDNNI-CIAVTVTVTGSIANAS 194
Query: 351 SQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG 530
V AR A + V +C++++ Y ++ P S LIA D
Sbjct: 195 KLVGEARTLALANNISRCQPMVVDSMCQKLS-----YELADQIHPFVVS--LIAGHDNNR 247
Query: 531 PCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSV 710
P +Y +DP G + A A G ++ + LE++ + DL+ + A +A+S L QV+
Sbjct: 248 PSLYYSDPFGSFQQCNAKAIGLRSEGADRSLEEQFNQ--DLTLEKAETIALSILKQVMGE 305
Query: 711 DFKSSEIEIGVVSKDNPXFRVLTETEID 794
+ ++I V+ P + + T +E++
Sbjct: 306 KVTPNNVDIAKVA---PAYHLYTFSELE 330
>UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2;
Desulfurococcales|Rep: Proteasome beta subunit -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 204
Score = 53.6 bits (123), Expect = 6e-06
Identities = 50/202 (24%), Positives = 89/202 (44%), Gaps = 4/202 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
G T+V RG V+AA+++V + + ++ +TD +G + G+ AD ++
Sbjct: 8 GATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKIL 67
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
R E + G I V + R +A I Y + P ++ + + +Y
Sbjct: 68 RAEIEYYNIVTGRRISVRAVARLLATILYSY----KYYPFLSETLVGGLEADGTAKLYVM 123
Query: 549 DPSGYYCS--YKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKS 722
DP G Y A+ +GA G LE K D+S DDA +LAI+ + + D S
Sbjct: 124 DPLGSLIEDDYAAIGSGAPIAIG--ILENGYSK--DMSVDDAKKLAIAAVRAAIERDAMS 179
Query: 723 SE-IEIGVVSKDNPXFRVLTET 785
+ I++ V+ ++ + E+
Sbjct: 180 GDGIDLLVIRREEDSIKAEEES 201
>UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome
endopeptidase complex - Candidatus Nitrosopumilus
maritimus SCM1
Length = 210
Score = 50.8 bits (116), Expect = 4e-05
Identities = 48/201 (23%), Positives = 90/201 (44%), Gaps = 2/201 (0%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQ-RKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
G T+V + D V+ A R + + + + D G + G +AD+++ V
Sbjct: 12 GTTTVGIKAKDGVVLCADMRASAGYFIANNNTMKIQKIDDHAGLTLAGGVADAQNIVDIL 71
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
RY + + + I +H L R S ++ QN P +++ YD E GP ++
Sbjct: 72 RYHSNLHRVEKHGPISIHSLARL---CSLIFHQNRGY-PFMADILVGGYDAE-GPALFNI 126
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE 728
D G V G+ + LE++ R DL+ ++A ++A+ + + + + +
Sbjct: 127 DMFGSVEKKAYVTTGSGSPVAYGLLEEEY--REDLTVEEAKKIALRAVKAAIVRNIGTGD 184
Query: 729 -IEIGVVSKDNPXFRVLTETE 788
I I ++ KD FR+LTE +
Sbjct: 185 GINIAIMDKDG--FRLLTEEQ 203
>UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 204
Score = 50.4 bits (115), Expect = 5e-05
Identities = 47/187 (25%), Positives = 86/187 (45%), Gaps = 2/187 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
T+V R +D V+AA+++V L L S ++ + D++G G++AD ++
Sbjct: 7 TTVGIRVSDGVVLAAEKRVSYGLYLMSKSGKKVYRILDKMGMASAGLMADMQTLA--RIV 64
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
EA Y+ S I + +A + + P +++ D+E G +Y DP
Sbjct: 65 EAEMRLYELDSNISPKVWT--VAKLLSYILYERRLFPYYAEIVVGGLDEE-GSHLYSLDP 121
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 731
G VA G+ T + +E KK D+S D+A+ LA+ + + D S + +
Sbjct: 122 IGAIIEDDYVALGSGTQLAISIVESNYKK--DMSLDEALSLALKSVYAAMKRDAASGDGV 179
Query: 732 EIGVVSK 752
++ V+ K
Sbjct: 180 DVLVIGK 186
>UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome
(prosome, macropain) subunit, alpha type, 8 isoform 2;
n=1; Macaca mulatta|Rep: PREDICTED: similar to
proteasome (prosome, macropain) subunit, alpha type, 8
isoform 2 - Macaca mulatta
Length = 261
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/90 (30%), Positives = 45/90 (50%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
+ G T+V RGT+ V+ ++K +L D +V + AL D + G+ AD+R + R
Sbjct: 29 KKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAGLTADARVVINR 88
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQ 455
AR E + + + V + R IA + Q
Sbjct: 89 ARVECQSHKLTVEDPVTVEYITRFIATLKQ 118
Score = 41.9 bits (94), Expect = 0.019
Identities = 16/27 (59%), Positives = 23/27 (85%)
Frame = +2
Query: 110 FDRHITIFSPEGRLYQVEYALKAINQG 190
+DR IT+FSP+G L+QVEYA +A+ +G
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKG 31
>UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis
vinifera|Rep: Proteasome subunit alpha type - Vitis
vinifera (Grape)
Length = 219
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/90 (31%), Positives = 43/90 (47%)
Frame = +3
Query: 186 RAGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
R G +V RGTD V+ ++K +L D +V + L D I G+ AD+R + R
Sbjct: 28 RKGNAAVGVRGTDTIVLGVEKKSTAKLQDSRTVRKIVNLDDHIALACAGLKADARVLINR 87
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQ 455
AR E + + + V + R IA + Q
Sbjct: 88 ARIECQSHRLTVEDPVTVEYITRYIAGLQQ 117
Score = 45.2 bits (102), Expect = 0.002
Identities = 18/29 (62%), Positives = 25/29 (86%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQG 190
A +DR IT+FSP+G L+QVEYAL+A+ +G
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKG 30
>UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome beta subunit -
Pyrobaculum aerophilum
Length = 202
Score = 44.8 bits (101), Expect = 0.003
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 2/196 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARY 374
T+V D V+A ++V + ++ + D + M+G +AD +S +
Sbjct: 3 TTVGIAVKDGVVLATDKRVTAGYYIAHKRGEKIWKIDDHVAATMSGGVADLQSVLSFLTL 62
Query: 375 EAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDP 554
A ++ +Y IP+ L ++ I ++ + + ++ D+E G +Y D
Sbjct: 63 RAHEYKIEYKRPIPISALVNYMSLI--LFYSRPYIYIV--HSIIGGVDEEEGAVLYMVDW 118
Query: 555 SGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-I 731
G K +A G+ + LE + R D++ +DA+ LAI + + D S E I
Sbjct: 119 LGTVTKEKYIATGSGSPYAKGALE--VGYREDMTLEDAVDLAIKAVKAAIRNDPGSGEGI 176
Query: 732 EIGVVSKDNPXFRVLT 779
++ V+++ RV T
Sbjct: 177 DVVVITRKEGFKRVFT 192
>UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2;
Oligohymenophorea|Rep: Proteasome subunit beta type -
Tetrahymena thermophila SB210
Length = 227
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 1/172 (0%)
Frame = +3
Query: 300 LTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEM 479
L +RI C+ +G AD+++ RY + V + +++ Y N
Sbjct: 62 LHERIYCLRSGSAADTQTLCSYVRYYLDVHSMELQRRPTVKTAAKLFSNLIYQYQDN--- 118
Query: 480 RPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLST 659
L ++++ DD GP +Y PSG + G+ + +Y++ + DL
Sbjct: 119 --LSAAVIVAGIDDNEGPSIYACQPSGSCIKQQVAIGGSGSGFIFSYVDANFRPNMDL-- 174
Query: 660 DDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNPXFRVLTETEIDRHLTAI 812
+ A +L + L+ +S D S I + ++KDN ++ H T I
Sbjct: 175 ESAKKLVKTALAHAMSRDGSSGGIIRLVNITKDNVTREFFDHKDLPYHFTNI 226
>UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT
ALPHA-4 - Encephalitozoon cuniculi
Length = 224
Score = 44.0 bits (99), Expect = 0.005
Identities = 41/160 (25%), Positives = 67/160 (41%)
Frame = +3
Query: 234 VAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEI 413
V+ +RK +RLL + + +I +G D+ + AR +++ G +I
Sbjct: 43 VSIERKSGNRLLLEEEKLFPISESQKIWMSYSGFKPDAYLVMNVARMICFSYKNSTGEDI 102
Query: 414 PVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAG 593
+ L R +++ Q YT RP G +L E P Y +P G + + A G
Sbjct: 103 AIDQLARMLSEYKQRYTVVYHQRPFGVRTVLFGL--EPRPVAYVLEPDGNFSEFFCGAIG 160
Query: 594 AKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD 713
K+ YLEK K D ++L I L +V+ D
Sbjct: 161 QKSQKVCEYLEKGEK-------GDLVRLTILGLMEVVQSD 193
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +2
Query: 107 GFDRHITIFSPEGRLYQVEYALKAINQGWVDICGXTRYRCSCSGSSTQGPR 259
GF+ + +FSP+GRL QVEYA +A QG + + G + S S G R
Sbjct: 2 GFEEQLAVFSPDGRLIQVEYAQQASEQGSLVVFGVDSEKISVSIERKSGNR 52
>UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1;
Spraguea lophii|Rep: 20S proteasome alpha subunit -
Spraguea lophii
Length = 99
Score = 42.7 bits (96), Expect = 0.011
Identities = 19/64 (29%), Positives = 37/64 (57%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
L+ ++D I C + G +D+ + AR +AA ++ ++G IP+ LC+++ I Q +T
Sbjct: 36 LYKISDGIHCCICGNSSDALQMIGYARLKAAEFEEEFGIPIPLLTLCKKVGAIKQNFTLG 95
Query: 471 AEMR 482
+R
Sbjct: 96 GGLR 99
>UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 195
Score = 42.7 bits (96), Expect = 0.011
Identities = 43/194 (22%), Positives = 86/194 (44%), Gaps = 2/194 (1%)
Frame = +3
Query: 213 RGTDAAVVAAQ-RKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANW 389
+ TD V+ A R + + + + D G + G +AD+++ V RY A+
Sbjct: 4 KATDGVVLCADMRASAGYFIANNNTMKIQRIDDHAGLTLAGGVADAQNIVDVLRYHASLH 63
Query: 390 QYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYC 569
+ + IP+ L R S ++ QN P +++ + D GP +Y D G
Sbjct: 64 RIRKQGPIPIKSLARL---TSLIFHQNRGY-PFMADILMGGF-DAVGPALYNIDMFGSVE 118
Query: 570 SYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVV 746
V G+ + LE++ R+DL+ D+A +A+ + ++ + + + I + V+
Sbjct: 119 EKSYVTTGSGSPVAYGTLEEEY--RADLTADEAKGVALRAVKAAITRNIGTGDGINVAVI 176
Query: 747 SKDNPXFRVLTETE 788
+ + F +LT +
Sbjct: 177 NGNG--FELLTREQ 188
>UniRef50_Q9U794 Cluster: Proteasome subunit beta type-1; n=7;
Trypanosomatidae|Rep: Proteasome subunit beta type-1 -
Trypanosoma brucei brucei
Length = 258
Score = 42.7 bits (96), Expect = 0.011
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 2/148 (1%)
Frame = +3
Query: 123 LLSFHLREDCIKLNMH*KQ*TRAGLTSVAXRGTDAAVVAAQRKVP-DRLLDPASVTH-LF 296
+L+ LR+ H T G T A G++ V+ A ++ D + S T LF
Sbjct: 29 VLTLPLRQGAKGHPQHWSPYTDNGGTIAAIAGSNYVVLGADTRLNGDFCIHTRSDTSKLF 88
Query: 297 ALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAE 476
LTDRI +GM AD +Y +QY G ++P + IA ++
Sbjct: 89 KLTDRIFLASSGMQADRLQLQQMLKYRIQWYQYNNGGKVP---STKAIAKLTSTMLYQRR 145
Query: 477 MRPLGCSMMLIAYDDEAGPCVYKTDPSG 560
P M++ D++ Y DP G
Sbjct: 146 FFPYYTFNMIVGIDEKGAGVCYSYDPVG 173
>UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia
intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia
ATCC 50803
Length = 245
Score = 41.1 bits (92), Expect = 0.033
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAI 181
SS D H +FSP+GR++Q+EYALK++
Sbjct: 2 SSNSHDTHANVFSPDGRIFQIEYALKSV 29
>UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2;
Trichomonas vaginalis|Rep: Proteasome subunit alpha type
- Trichomonas vaginalis G3
Length = 251
Score = 41.1 bits (92), Expect = 0.033
Identities = 16/31 (51%), Positives = 24/31 (77%)
Frame = +2
Query: 98 SSAGFDRHITIFSPEGRLYQVEYALKAINQG 190
S + +DR++ FSP+GRL QVEYA++A+ G
Sbjct: 4 SGSEYDRNVNTFSPDGRLLQVEYAIEAVKLG 34
>UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar to
human proteasome (prosome, macropain) subunit, alpha
type, 5(PSMA5),; n=1; Macaca fascicularis|Rep: Testis
cDNA, clone: QtsA-18608, similar to human proteasome
(prosome, macropain) subunit, alpha type, 5(PSMA5), -
Macaca fascicularis (Crab eating macaque) (Cynomolgus
monkey)
Length = 117
Score = 40.7 bits (91), Expect = 0.044
Identities = 24/92 (26%), Positives = 47/92 (51%)
Frame = +3
Query: 519 DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQ 698
DE GP ++ DPSG + A A G+ + + L++ K ++ +AI+ ++ L Q
Sbjct: 23 DEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSSLIILKQ 80
Query: 699 VLSVDFKSSEIEIGVVSKDNPXFRVLTETEID 794
V+ ++ IE+ V + F + T+ E++
Sbjct: 81 VMEEKLNATNIELATV-QPGQNFHMFTKEELE 111
>UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum
pernix|Rep: Proteasome beta subunit - Aeropyrum pernix
Length = 203
Score = 39.1 bits (87), Expect = 0.13
Identities = 38/176 (21%), Positives = 68/176 (38%), Gaps = 1/176 (0%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVP-DRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*R 365
AG T++ R D V+AA +++ + + +F + DRIG G+ D V
Sbjct: 4 AGATALGIRVEDGVVLAADKRMSYGGFILSRNFKKIFVINDRIGIAFAGLYGDMGGLVRI 63
Query: 366 ARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYK 545
+ + G V + + ++ + Y + P ++ D P +Y
Sbjct: 64 VEGQMRLASLETGKPATVRNVAKFLSSLLYSY----KFFPFNVEAIVGGIDPGGEPKLYV 119
Query: 546 TDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD 713
DP G VAAG LE K+ +S ++A + A+ L ++ D
Sbjct: 120 LDPLGSIIEEDYVAAGTGATTAFGLLEHVYKR--GMSLEEAKKAAVEALRASMARD 173
>UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY
SUBUNIT 8 - Encephalitozoon cuniculi
Length = 242
Score = 38.3 bits (85), Expect = 0.23
Identities = 41/190 (21%), Positives = 78/190 (41%), Gaps = 1/190 (0%)
Frame = +3
Query: 189 AGLTSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
+G T + + V+ A++ L S + + + IG V TGM +D+
Sbjct: 28 SGDTCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIGNTIGVVCTGMSSDTFYVGCAI 87
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
+ + + + + ++ + DI +T+ +R LG + + Y D + ++ T
Sbjct: 88 KDYVFHHKENFNEDPTPGMMKVYLNDIFHYFTRGINLRVLGANTLTSVYKDGSFSLLH-T 146
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVD-FKSS 725
D SG SYKA G T LEK ++ ++ + + + L K
Sbjct: 147 DCSGKTLSYKAACIGKGTRRIKTELEK--LDIDTMTIEEMVDVGVKVLYMAHDPSKDKEF 204
Query: 726 EIEIGVVSKD 755
+IEIG+ S +
Sbjct: 205 DIEIGIASME 214
>UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia
theta|Rep: 26S proteasome SU alpha7 - Guillardia theta
(Cryptomonas phi)
Length = 241
Score = 36.3 bits (80), Expect = 0.94
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +2
Query: 104 AGFDRHITIFSPEGRLYQVEYALKAINQ 187
+G+D TIF+PEG+L Q+EY+ K IN+
Sbjct: 6 SGYDLLPTIFTPEGKLLQLEYSSKCINK 33
Score = 34.3 bits (75), Expect = 3.8
Identities = 36/159 (22%), Positives = 65/159 (40%)
Frame = +3
Query: 291 LFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQN 470
+F L + +G+ D RS R E +Y+YG E+ L ++ + + + +
Sbjct: 67 IFCLNHYMAMTSSGITGDFRSLCNRLVDENLIEKYRYGLELNSKYLTHLLSRLFHLNSNS 126
Query: 471 AEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSD 650
+RPL C ++L + D + ++ G ++ G+ N LE K+ +
Sbjct: 127 WSLRPLACDIIL-GFIDYSSLEIFFISNQGSIIKTNNISTGSACELINFELESIFKE--E 183
Query: 651 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXF 767
LS I I LS L+ D +S + +K F
Sbjct: 184 LSCRKVILKIIKKLS-ALTRDLQSKYFYVKYFAKKKKKF 221
>UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giardia
lamblia ATCC 50803|Rep: Proteasome subunit beta type -
Giardia lamblia ATCC 50803
Length = 254
Score = 35.9 bits (79), Expect = 1.2
Identities = 40/192 (20%), Positives = 82/192 (42%), Gaps = 4/192 (2%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSRSQV*RA 368
G T +A G D A++A ++ + + +V +F +TD+I +GM AD + +
Sbjct: 55 GGTIIAIAGPDFAMIAGDTRLSEGYNILSRNVRKVFPVTDKIVYAASGMHADVQRLLKHM 114
Query: 369 RYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKT 548
+ E+ + K EI + R ++ + +Y + + P S ++ D E VY
Sbjct: 115 KIESTEYYLKTQKEIAIEQFIRLLS--AMMYYRRS--FPWYTSSIVAGIDSEGRGAVYSY 170
Query: 549 DPSGYYCSYKAVAAGAKTVDGNAYLEKKL--KKRSDLSTDDAIQLAISCLSQVLSVDFKS 722
D G + +AG L++ + K ++++ + A +L S D +
Sbjct: 171 DVIGSTLRTRYGSAGTGNAMICPILDEAILSKNEAEITREFAFELIQSAFRSCAERDIYT 230
Query: 723 SEIEIGV-VSKD 755
+ + + +S D
Sbjct: 231 GDSVVAMCISAD 242
>UniRef50_Q980L4 Cluster: Proteasome subunit; n=4;
Sulfolobaceae|Rep: Proteasome subunit - Sulfolobus
solfataricus
Length = 196
Score = 35.9 bits (79), Expect = 1.2
Identities = 43/188 (22%), Positives = 78/188 (41%), Gaps = 3/188 (1%)
Frame = +3
Query: 198 TSVAXRGTDAAVVAAQRKVPDRLLDPASVTHLFALTDRIGCVMTGMIADSRSQV*RARYE 377
T+V + D V+A++R++ + ++ G+ D ++ E
Sbjct: 7 TAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVE 66
Query: 378 AANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPS 557
++ G I VH + ++ I Y ++ P S +L DE GP +Y DP
Sbjct: 67 IKYYEVSTGKPISVHAAAKLLSVILYQY----KVMPF-ISEILFGGVDEKGPQLYVLDPI 121
Query: 558 GYYC--SYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSE- 728
G +Y AV +GA+ G LE + ++S D A QL + + D S +
Sbjct: 122 GSLIEDNYAAVGSGARIAIG--VLESEYD--PNMSLDVATQLITKAIKASIERDITSGDG 177
Query: 729 IEIGVVSK 752
I++ ++ K
Sbjct: 178 IDLAIIDK 185
>UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9;
Magnoliophyta|Rep: Proteasome subunit beta type-2-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 204
Score = 35.9 bits (79), Expect = 1.2
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
Frame = +3
Query: 393 YKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCS 572
YK+ + IP+ ++ T P ++++ YDDE+G +Y D Y +
Sbjct: 67 YKFRNGIPLTTAAAANFTRGELATA-LRKNPYSVNILMAGYDDESGASLYYID---YIAT 122
Query: 573 YKAVAAGAKTVDGNAYLEKKLKK--RSDLSTDDAIQLAISCLSQVLS-VDFKSSEIEIGV 743
V GA G+ + + + RSD+S ++AI+L C+ ++ S + I +
Sbjct: 123 LHKVDKGAFGY-GSYFSLSTMDRHYRSDMSVEEAIELVDKCILEIRSRLVVAPPNFVIKI 181
Query: 744 VSKD 755
V KD
Sbjct: 182 VDKD 185
>UniRef50_UPI0000DB72B7 Cluster: PREDICTED: similar to CG3558-PA,
isoform A; n=2; Apis mellifera|Rep: PREDICTED: similar
to CG3558-PA, isoform A - Apis mellifera
Length = 958
Score = 34.7 bits (76), Expect = 2.9
Identities = 14/48 (29%), Positives = 25/48 (52%)
Frame = +3
Query: 273 PASVTHLFALTDRIGCVMTGMIADSRSQV*RARYEAANWQYKYGSEIP 416
PAS+ + L+D + + D+R ++ R +NW Y+Y E+P
Sbjct: 497 PASINYGVRLSDSLYGNYHAYLCDARQKIRACRIACSNWSYQYNGELP 544
>UniRef50_Q0FG88 Cluster: Putative uncharacterized protein; n=1;
alpha proteobacterium HTCC2255|Rep: Putative
uncharacterized protein - alpha proteobacterium HTCC2255
Length = 154
Score = 34.7 bits (76), Expect = 2.9
Identities = 20/71 (28%), Positives = 34/71 (47%)
Frame = +3
Query: 588 AGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXF 767
AG D A E+KL KR+D S +A IS + +L K++E+EI +
Sbjct: 55 AGLLLADRTAASEEKLSKRNDASYSEAPDSEISKHNSILDTKLKAAELEISNLKSQISNQ 114
Query: 768 RVLTETEIDRH 800
+ ++ + D +
Sbjct: 115 HISSDKDTDNN 125
>UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr14 scaffold_54, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 66
Score = 34.7 bits (76), Expect = 2.9
Identities = 19/62 (30%), Positives = 28/62 (45%)
Frame = +3
Query: 591 GAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPXFR 770
G + +LEK+ D+ DDA+ AI L + S IEIG++ D +
Sbjct: 2 GKNVSNAKTFLEKRYT--DDMELDDAVHTAILTLKEGFEGQISSKNIEIGIIGTDRKFRQ 59
Query: 771 VL 776
VL
Sbjct: 60 VL 61
>UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella
chejuensis KCTC 2396|Rep: Outer membrane protein -
Hahella chejuensis (strain KCTC 2396)
Length = 587
Score = 34.3 bits (75), Expect = 3.8
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +3
Query: 675 LAISCLSQVLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDR 797
LA+S LS + + F S +++ VV +DN + L E E+DR
Sbjct: 14 LAVSGLSHAIDIPFFSDKLKYEVVVEDNEELKSLVEDELDR 54
>UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;
Sulfolobaceae|Rep: Proteasome subunit beta precursor -
Sulfolobus solfataricus
Length = 208
Score = 33.9 bits (74), Expect = 5.0
Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 3/166 (1%)
Frame = +3
Query: 192 GLTSVAXRGTDAAVVAAQRKVPDRL-LDPASVTHLFALTDRIGCVMTGMIADSR--SQV* 362
G T+V R D ++AA R+ + V + +TD+IG G +AD + V
Sbjct: 14 GTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVL 73
Query: 363 RARYEAANWQYKYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVY 542
+ Y N KYG I + + R+A++ + P +++ YDD+ P ++
Sbjct: 74 KNIYH-YNSITKYG-PISIKGIATRLANVLSA----TKYFPYIVQILIGGYDDQ--PRLF 125
Query: 543 KTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLA 680
D G VA G+ + LE + + ++ D+A LA
Sbjct: 126 NLDYLGDITEENYVATGSGSPVAMGVLEDEYNPK--MTLDEAADLA 169
>UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Putative
uncharacterized protein - Flavobacteriales bacterium
HTCC2170
Length = 1157
Score = 33.5 bits (73), Expect = 6.6
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +3
Query: 627 KKLKKRSDLSTDDAIQLAISCLSQ-VLSVDFKSSEIEIGVVSKDNPXFRVLTETEIDR 797
KKL K+ L ++ ++ IS Q L+VDF+ E+G + KDN + + E+++
Sbjct: 662 KKLSKKQSLLSEQKLKEEISAQEQRELNVDFEELANELGELEKDNQDLKKPIDLEVNK 719
>UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1;
Trichomonas vaginalis G3|Rep: Proteasome subunit beta
type - Trichomonas vaginalis G3
Length = 216
Score = 33.5 bits (73), Expect = 6.6
Identities = 19/71 (26%), Positives = 36/71 (50%)
Frame = +3
Query: 519 DEAGPCVYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQ 698
D AGP VY + SG K + G+ + AY+++ R D++ ++A + AI+ ++
Sbjct: 118 DSAGPQVYSIEVSGMAIKKKIASNGSGSTYIQAYIDQNY--REDMTMEEATKFAIAAVTG 175
Query: 699 VLSVDFKSSEI 731
+ D S +
Sbjct: 176 AIIRDGSSGGV 186
>UniRef50_Q54Q21 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1050
Score = 33.1 bits (72), Expect = 8.8
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Frame = -1
Query: 331 PVMTHPILSVRANR*VTEAGSSSLSGTLR*AATTAASVPRXATDVNPALVYCFQCIFNL- 155
P+MT P+L + N T SSS+S +L + ++ + + ++ VN A VY N+
Sbjct: 601 PLMTSPLLEMYQNPTSTFKPSSSVSSSLSSSTSSTTTTTKTSSTVNQASVYQVSPNVNIN 660
Query: 154 -IQSSLR 137
IQS L+
Sbjct: 661 SIQSQLQ 667
>UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 485
Score = 33.1 bits (72), Expect = 8.8
Identities = 32/121 (26%), Positives = 54/121 (44%)
Frame = +3
Query: 396 KYGSEIPVHILCRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCVYKTDPSGYYCSY 575
KYGS++ + I IS ++ + + L C+ L A +D G + Y+CS
Sbjct: 136 KYGSKLKITTDNYTILSISALFCKIIQTN-LNCA--LSAVND--GIIINAISSIEYFCST 190
Query: 576 KAVAAGAKTVDGNAYLEKKLKKRSDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 755
+ K V+ N Y+ K L DL + +Q S +S +L + +S E+ + K
Sbjct: 191 GYIGFFCKYVNSNIYILKYLFSYHDLISKAQVQ---SIISTMLKLLITTSSDEVSPIDKR 247
Query: 756 N 758
N
Sbjct: 248 N 248
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 741,796,503
Number of Sequences: 1657284
Number of extensions: 13865704
Number of successful extensions: 37562
Number of sequences better than 10.0: 136
Number of HSP's better than 10.0 without gapping: 36002
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37493
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 72143915536
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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