Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_pT_M05
(827 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 155 1e-37
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 155 1e-37
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 149 9e-36
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 149 9e-36
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 149 9e-36
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 149 9e-36
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 149 9e-36
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 146 6e-35
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 146 6e-35
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 146 6e-35
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 146 6e-35
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 134 4e-31
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 134 4e-31
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 134 4e-31
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 134 5e-31
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 129 1e-29
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 129 1e-29
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 129 1e-29
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 95 2e-19
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 95 2e-19
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 87 6e-17
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 87 6e-17
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 87 6e-17
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 79 3e-14
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 79 3e-14
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 67 8e-11
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 67 8e-11
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 66 1e-10
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 65 3e-10
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 65 3e-10
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 65 3e-10
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 65 3e-10
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 65 3e-10
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 65 3e-10
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 65 3e-10
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 65 3e-10
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 59 2e-08
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 58 4e-08
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 58 5e-08
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 54 8e-07
AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant pro... 40 0.008
DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor pote... 31 3.9
BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein. 31 3.9
AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein. 31 3.9
AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor pote... 31 3.9
AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor pote... 31 3.9
AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation cha... 31 3.9
AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor pote... 31 3.9
AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor pote... 31 3.9
AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein. 31 3.9
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 30 8.9
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 155 bits (377), Expect = 1e-37
Identities = 91/250 (36%), Positives = 137/250 (54%), Gaps = 6/250 (2%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF+ + Y +GG SG HV TN KR+ VKGKR++R +V+ S N+GD F
Sbjct: 97 FRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVF 156
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIV--DKYSSDVDVQKFF 471
+L L I + G ++ + E+LKA+ A +RD++ GR ++ ++ DK ++ ++ K
Sbjct: 157 LLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVL 216
Query: 470 -TALG--SGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQEN 303
LG S +K VPDE ++ + S ++L +SD+ G++ VT + ++P Q+
Sbjct: 217 QDTLGRRSIIKPTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDL 269
Query: 302 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEP 123
L+ + YILD IYVW GK AT EK AM+KA + K+YPS V V E
Sbjct: 270 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 329
Query: 122 AAFKQYFFTW 93
A FKQ F W
Sbjct: 330 AMFKQLFQKW 339
Score = 65.3 bits (152), Expect = 3e-10
Identities = 64/250 (25%), Positives = 111/250 (44%), Gaps = 6/250 (2%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGD 651
F + F+ L EGG N R+FQ+ G K + + +V +S+N D
Sbjct: 478 FMAIFKGKLVIFEGGTSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 534
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
F+L + Y++ G+ + E+ A A+ + D G + V + + +F+
Sbjct: 535 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD------GSENTV---AEGQEPAEFW 585
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQ 291
LG G D+ + + + L E S+ TG+ VT ++ F Q++L+P
Sbjct: 586 DLLG-GKTPYANDKRLQQEILDVQSR------LFECSNKTGQFVVTEITD-FTQDDLNPT 637
Query: 290 NAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEP 123
+ +LDT +++WIG +A A EK A+ AQ+ L+ +PS + + Q EP
Sbjct: 638 DVMLLDTWD-QVFLWIGAEANATEKESALATAQQYLH--THPSGRDPDTPILIIKQGFEP 694
Query: 122 AAFKQYFFTW 93
F +F W
Sbjct: 695 PIFTGWFLAW 704
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 155 bits (377), Expect = 1e-37
Identities = 91/250 (36%), Positives = 137/250 (54%), Gaps = 6/250 (2%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF+ + Y +GG SG HV TN KR+ VKGKR++R +V+ S N+GD F
Sbjct: 104 FRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVF 163
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIV--DKYSSDVDVQKFF 471
+L L I + G ++ + E+LKA+ A +RD++ GR ++ ++ DK ++ ++ K
Sbjct: 164 LLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVL 223
Query: 470 -TALG--SGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQEN 303
LG S +K VPDE ++ + S ++L +SD+ G++ VT + ++P Q+
Sbjct: 224 QDTLGRRSIIKPTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDL 276
Query: 302 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEP 123
L+ + YILD IYVW GK AT EK AM+KA + K+YPS V V E
Sbjct: 277 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 336
Query: 122 AAFKQYFFTW 93
A FKQ F W
Sbjct: 337 AMFKQLFQKW 346
Score = 65.3 bits (152), Expect = 3e-10
Identities = 64/250 (25%), Positives = 111/250 (44%), Gaps = 6/250 (2%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGD 651
F + F+ L EGG N R+FQ+ G K + + +V +S+N D
Sbjct: 485 FMAIFKGKLVIFEGGTSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
F+L + Y++ G+ + E+ A A+ + D G + V + + +F+
Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD------GSENTV---AEGQEPAEFW 592
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQ 291
LG G D+ + + + L E S+ TG+ VT ++ F Q++L+P
Sbjct: 593 DLLG-GKTPYANDKRLQQEILDVQSR------LFECSNKTGQFVVTEITD-FTQDDLNPT 644
Query: 290 NAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEP 123
+ +LDT +++WIG +A A EK A+ AQ+ L+ +PS + + Q EP
Sbjct: 645 DVMLLDTWD-QVFLWIGAEANATEKESALATAQQYLH--THPSGRDPDTPILIIKQGFEP 701
Query: 122 AAFKQYFFTW 93
F +F W
Sbjct: 702 PIFTGWFLAW 711
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 149 bits (362), Expect = 9e-36
Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGDCF
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
++ L +IY + G E+LKA A +R + GR ++ +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 297
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 296 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 119 AFKQYFFTWRD 87
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = -1
Query: 731 RMFQVKGKRD--VRVRQVDPQIASMNKGDCFVLSL-DNDIYVFVGEKAKNVEKLKAISFA 561
R+FQV+ R+ +VD S+N D FVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 560 NQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 381
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 380 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 201
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 200 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 93
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 149 bits (362), Expect = 9e-36
Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGDCF
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
++ L +IY + G E+LKA A +R + GR ++ +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 297
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 296 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 119 AFKQYFFTWRD 87
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = -1
Query: 731 RMFQVKGKRD--VRVRQVDPQIASMNKGDCFVLSL-DNDIYVFVGEKAKNVEKLKAISFA 561
R+FQV+ R+ +VD S+N D FVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 560 NQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 381
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 380 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 201
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 200 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 93
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 149 bits (362), Expect = 9e-36
Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGDCF
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
++ L +IY + G E+LKA A +R + GR ++ +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 297
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 296 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 119 AFKQYFFTWRD 87
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = -1
Query: 731 RMFQVKGKRD--VRVRQVDPQIASMNKGDCFVLSLD-NDIYVFVGEKAKNVEKLKAISFA 561
R+FQV+ R+ +VD S+N D FVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLSQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 560 NQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 381
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 380 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 201
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 200 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 93
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 149 bits (362), Expect = 9e-36
Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGDCF
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
++ L +IY + G E+LKA A +R + GR ++ +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 297
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 296 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 119 AFKQYFFTWRD 87
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 149 bits (362), Expect = 9e-36
Identities = 91/251 (36%), Positives = 132/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGDCF
Sbjct: 153 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 212
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
++ L +IY + G E+LKA A +R + GR ++ +V++ S ++ K
Sbjct: 213 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 270
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 297
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 271 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 324
Query: 296 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 325 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 384
Query: 119 AFKQYFFTWRD 87
FKQ+F WRD
Sbjct: 385 IFKQFFKDWRD 395
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 146 bits (355), Expect = 6e-35
Identities = 92/274 (33%), Positives = 138/274 (50%), Gaps = 5/274 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L N+I+ + G + E+LKA + +RD + GR +V + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 291
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 290 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 114
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 113 KQYFFTWRDFGMSHSRVI*KLKAQ--NKEKVP*D 18
KQ+F WRD + + L + N E+VP D
Sbjct: 390 KQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFD 423
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 212 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 146 bits (355), Expect = 6e-35
Identities = 92/274 (33%), Positives = 138/274 (50%), Gaps = 5/274 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L N+I+ + G + E+LKA + +RD + GR +V + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 291
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 290 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 114
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 113 KQYFFTWRDFGMSHSRVI*KLKAQ--NKEKVP*D 18
KQ+F WRD + + L + N E+VP D
Sbjct: 390 KQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFD 423
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 212 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 146 bits (355), Expect = 6e-35
Identities = 92/274 (33%), Positives = 138/274 (50%), Gaps = 5/274 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 106 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 165
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L N+I+ + G + E+LKA + +RD + GR +V + ++ + +
Sbjct: 166 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 222
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 291
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 223 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 278
Query: 290 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 114
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 279 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 338
Query: 113 KQYFFTWRDFGMSHSRVI*KLKAQ--NKEKVP*D 18
KQ+F WRD + + L + N E+VP D
Sbjct: 339 KQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFD 372
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 508 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 567
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 568 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 614
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 615 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 670
Query: 212 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 671 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 714
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 146 bits (355), Expect = 6e-35
Identities = 92/274 (33%), Positives = 138/274 (50%), Gaps = 5/274 (1%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L N+I+ + G + E+LKA + +RD + GR +V + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 291
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 290 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 114
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 113 KQYFFTWRDFGMSHSRVI*KLKAQ--NKEKVP*D 18
KQ+F WRD + + L + N E+VP D
Sbjct: 390 KQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFD 423
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 212 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 134 bits (324), Expect = 4e-31
Identities = 82/250 (32%), Positives = 129/250 (51%), Gaps = 4/250 (1%)
Frame = -1
Query: 827 LFXSYFQTPLTYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGD 651
LF SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGD 164
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
CF+L L +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 165 CFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLS 297
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 -----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLI 278
Query: 296 PQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 279 SDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESP 338
Query: 119 AFKQYFFTWR 90
FKQ+F W+
Sbjct: 339 IFKQFFKDWK 348
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 134 bits (324), Expect = 4e-31
Identities = 82/250 (32%), Positives = 129/250 (51%), Gaps = 4/250 (1%)
Frame = -1
Query: 827 LFXSYFQTPLTYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGD 651
LF SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGD 164
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
CF+L L +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 165 CFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLS 297
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 -----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLI 278
Query: 296 PQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 279 SDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESP 338
Query: 119 AFKQYFFTWR 90
FKQ+F W+
Sbjct: 339 IFKQFFKDWK 348
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 134 bits (324), Expect = 4e-31
Identities = 82/250 (32%), Positives = 129/250 (51%), Gaps = 4/250 (1%)
Frame = -1
Query: 827 LFXSYFQTPLTYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGD 651
LF SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGD 164
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
CF+L L +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 165 CFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLS 297
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 -----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLI 278
Query: 296 PQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 279 SDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESP 338
Query: 119 AFKQYFFTWR 90
FKQ+F W+
Sbjct: 339 IFKQFFKDWK 348
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 134 bits (323), Expect = 5e-31
Identities = 82/250 (32%), Positives = 129/250 (51%), Gaps = 4/250 (1%)
Frame = -1
Query: 827 LFXSYFQTPLTYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGD 651
LF SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGD 164
Query: 650 CFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFF 471
CF+L L +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 165 CFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL 224
Query: 470 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLS 297
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 -----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLI 278
Query: 296 PQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 120
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 279 SDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESP 338
Query: 119 AFKQYFFTWR 90
FKQ+F W+
Sbjct: 339 IFKQFFKDWK 348
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 124/245 (50%), Gaps = 1/245 (0%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GD F
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 288
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 287 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 108
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 107 YFFTW 93
F W
Sbjct: 345 LFQKW 349
Score = 70.9 bits (166), Expect = 5e-12
Identities = 73/266 (27%), Positives = 118/266 (44%), Gaps = 6/266 (2%)
Frame = -1
Query: 818 SYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDCF 645
S F+ + +GG S N++ T G R+FQV+G + + +V + +N D F
Sbjct: 490 SIFKGRMVVYQGGT-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVF 546
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
VL + Y++ G+ E+ A A+ + R + +V + + F+ A
Sbjct: 547 VLKTQSCCYLWCGKGCSGDEREMAKMVADTI------SRTEKQVVVEGQEPAN---FWMA 597
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNA 285
LG P +T +E N L E S+ TG+ T + F Q++L +
Sbjct: 598 LGGKA----PYANTKRLQEE---NLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDV 649
Query: 284 YILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAA 117
++LD + ++ WIGK A EK A T AQE L K +PS + V Q EP
Sbjct: 650 FLLD-VWDQVFFWIGKHANEEEKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPT 706
Query: 116 FKQYFFTWRDFGMSHSRVI*KLKAQN 39
F +F W F S+++ LKA++
Sbjct: 707 FTGWFLAWDPFKWSNTKSYEDLKAES 732
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 124/245 (50%), Gaps = 1/245 (0%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GD F
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 288
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 287 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 108
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 107 YFFTW 93
F W
Sbjct: 345 LFQKW 349
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 124/245 (50%), Gaps = 1/245 (0%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GD F
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L L I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 288
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 287 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 108
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 107 YFFTW 93
F W
Sbjct: 345 LFQKW 349
Score = 70.5 bits (165), Expect = 7e-12
Identities = 73/265 (27%), Positives = 117/265 (44%), Gaps = 6/265 (2%)
Frame = -1
Query: 818 SYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDCF 645
S F+ + +GG S N++ T G R+FQV+G + + +V + +N D F
Sbjct: 490 SIFKGRMVVYQGGT-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVF 546
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
VL + Y++ G+ E+ A A+ + R + +V + + F+ A
Sbjct: 547 VLKTQSCCYLWCGKGCSGDEREMAKMVADTI------SRTEKQVVVEGQEPAN---FWMA 597
Query: 464 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNA 285
LG P +T +E N L E S+ TG+ T + F Q++L +
Sbjct: 598 LGGKA----PYANTKRLQEE---NLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDV 649
Query: 284 YILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAA 117
++LD + ++ WIGK A EK A T AQE L K +PS + V Q EP
Sbjct: 650 FLLD-VWDQVFFWIGKHANEEEKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPT 706
Query: 116 FKQYFFTWRDFGMSHSRVI*KLKAQ 42
F +F W F S+++ LKA+
Sbjct: 707 FTGWFLAWDPFKWSNTKSYEDLKAE 731
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 95.5 bits (227), Expect = 2e-19
Identities = 44/107 (41%), Positives = 64/107 (59%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 106 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 165
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDK 504
+L L N+I+ + G + E+LKA + +RD + GR +V + ++
Sbjct: 166 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 212
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 95.5 bits (227), Expect = 2e-19
Identities = 44/107 (41%), Positives = 64/107 (59%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GDCF
Sbjct: 117 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 176
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDK 504
+L L N+I+ + G + E+LKA + +RD + GR +V + ++
Sbjct: 177 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 223
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 87.4 bits (207), Expect = 6e-17
Identities = 67/257 (26%), Positives = 122/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ F
Sbjct: 590 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 648
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L DIYV+ G +A KA FA ++ + G+ ++ ++ ++ +F+ A
Sbjct: 649 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 705
Query: 464 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 318
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 706 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 764
Query: 317 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 138
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 765 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 823
Query: 137 QNTEPAAFKQYFFTWRD 87
+ TE FK F W D
Sbjct: 824 EGTEAQVFKAKFKNWDD 840
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 87.4 bits (207), Expect = 6e-17
Identities = 67/257 (26%), Positives = 122/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ F
Sbjct: 589 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 647
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L DIYV+ G +A KA FA ++ + G+ ++ ++ ++ +F+ A
Sbjct: 648 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 704
Query: 464 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 318
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 705 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 763
Query: 317 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 138
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 764 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 822
Query: 137 QNTEPAAFKQYFFTWRD 87
+ TE FK F W D
Sbjct: 823 EGTEAQVFKAKFKNWDD 839
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 87.4 bits (207), Expect = 6e-17
Identities = 67/257 (26%), Positives = 122/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ F
Sbjct: 590 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 648
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L DIYV+ G +A KA FA ++ + G+ ++ ++ ++ +F+ A
Sbjct: 649 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 705
Query: 464 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 318
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 706 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 764
Query: 317 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 138
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 765 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 823
Query: 137 QNTEPAAFKQYFFTWRD 87
+ TE FK F W D
Sbjct: 824 EGTEAQVFKAKFKNWDD 840
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 78.6 bits (185), Expect = 3e-14
Identities = 52/177 (29%), Positives = 85/177 (48%), Gaps = 3/177 (1%)
Frame = -1
Query: 608 GEKAKNVEKLKAISFANQVRDQDHHG-RGKVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 435
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGCRVGSL-- 64
Query: 434 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKP-FKQENLSPQNAYILDTISGN 258
++ + + +NV L V + + V L+ P Q+ L ++ YILD
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK 122
Query: 257 IYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
IYVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 42.3 bits (95), Expect = 0.002
Identities = 57/235 (24%), Positives = 99/235 (42%), Gaps = 11/235 (4%)
Frame = -1
Query: 764 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKN 591
+H + + R+FQV+G + R +V + +S+N D F+L + Y++ G+
Sbjct: 328 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 387
Query: 590 VEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQ-----KFFTALGSGVKDLVPDES 426
DQ R V ++ + + + ++ F+ ALG P S
Sbjct: 388 --------------DQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRA----PYPS 429
Query: 425 TGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVW 246
+E + L E S G + + + F QE+L + +LDT I++W
Sbjct: 430 NKRLPEEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLW 484
Query: 245 IGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 93
+G+ A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 485 LGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 535
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 78.6 bits (185), Expect = 3e-14
Identities = 52/177 (29%), Positives = 85/177 (48%), Gaps = 3/177 (1%)
Frame = -1
Query: 608 GEKAKNVEKLKAISFANQVRDQDHHG-RGKVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 435
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL-- 64
Query: 434 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKP-FKQENLSPQNAYILDTISGN 258
++ + + +NV L V + + V L+ P Q+ L ++ YILD
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK 122
Query: 257 IYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
IYVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 42.3 bits (95), Expect = 0.002
Identities = 57/235 (24%), Positives = 99/235 (42%), Gaps = 11/235 (4%)
Frame = -1
Query: 764 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKN 591
+H + + R+FQV+G + R +V + +S+N D F+L + Y++ G+
Sbjct: 328 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 387
Query: 590 VEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQ-----KFFTALGSGVKDLVPDES 426
DQ R V ++ + + + ++ F+ ALG P S
Sbjct: 388 --------------DQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRA----PYPS 429
Query: 425 TGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVW 246
+E + L E S G + + + F QE+L + +LDT I++W
Sbjct: 430 NKRLPEEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLW 484
Query: 245 IGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 93
+G+ A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 485 LGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 535
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 62 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 121
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 122 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 168
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 169 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 224
Query: 212 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 225 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 268
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 66.9 bits (156), Expect = 8e-11
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 5/124 (4%)
Frame = -1
Query: 374 LSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAM 204
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+ A+
Sbjct: 31 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 90
Query: 203 TKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ--NKEK 30
A + + +YP QV+ + + E FKQ+F WRD + + L + N E+
Sbjct: 91 KTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVER 150
Query: 29 VP*D 18
VP D
Sbjct: 151 VPFD 154
Score = 54.4 bits (125), Expect = 5e-07
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 2/188 (1%)
Frame = -1
Query: 746 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKA 573
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 290 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 349
Query: 572 ISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 393
+R Q V + + D F+ ALG S D++ + +
Sbjct: 350 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 396
Query: 392 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 213
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 397 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 452
Query: 212 QAMTKAQE 189
+A+T ++
Sbjct: 453 EALTSGED 460
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 66.1 bits (154), Expect = 1e-10
Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = -1
Query: 365 VSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKA 195
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM A
Sbjct: 7 VSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTA 66
Query: 194 QELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
+E L NY Q+ + + E FKQ+F WRD
Sbjct: 67 EEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 102
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = -1
Query: 731 RMFQVKGKRD--VRVRQVDPQIASMNKGDCFVLSL-DNDIYVFVGEKAKNVEKLKAISFA 561
R+FQV+ R+ +VD S+N D FVL L N Y++VG+ A E+ A A
Sbjct: 264 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 323
Query: 560 NQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 381
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 324 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 368
Query: 380 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 201
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 369 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 425
Query: 200 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 93
A+ L + + + Q EP F +F W
Sbjct: 426 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/176 (28%), Positives = 81/176 (46%), Gaps = 2/176 (1%)
Frame = -1
Query: 608 GEKAKNVEKLKAISFANQVRDQDHHG-RGKVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 435
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL-- 64
Query: 434 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNI 255
++ + + +NV L V + GK + L ++ YILD I
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEK-GK------------DLLQEEDFYILDQGGFKI 109
Query: 254 YVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 87
YVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 110 YVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 165
Score = 42.3 bits (95), Expect = 0.002
Identities = 57/235 (24%), Positives = 99/235 (42%), Gaps = 11/235 (4%)
Frame = -1
Query: 764 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKN 591
+H + + R+FQV+G + R +V + +S+N D F+L + Y++ G+
Sbjct: 314 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 373
Query: 590 VEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQ-----KFFTALGSGVKDLVPDES 426
DQ R V ++ + + + ++ F+ ALG P S
Sbjct: 374 --------------DQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRA----PYPS 415
Query: 425 TGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVW 246
+E + L E S G + + + F QE+L + +LDT I++W
Sbjct: 416 NKRLPEEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLW 470
Query: 245 IGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 93
+G+ A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 471 LGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 521
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 64.9 bits (151), Expect = 3e-10
Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 728 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVR 549
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 548 DQDHHGRGKV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 378
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 377 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 210
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 209 AMTKAQELLN 180
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 59.3 bits (137), Expect = 2e-08
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 2/200 (1%)
Frame = -1
Query: 680 PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKY 501
P+ ++N D FVL + Y++VG A EK A +R Q V + +
Sbjct: 8 PKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVAEGS 61
Query: 500 SSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSK 321
D F+ ALG S D++ + + L S+ G+ + +
Sbjct: 62 EPD----GFWEALGGKAAYRT---SPRLKDKKMDAHPPR---LFACSNKIGRFVIEEVPG 111
Query: 320 PFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL--NAKNYPSWVQVT 147
QE+L+ + +LDT ++VW+GK + EK++A+T A+ + + N +T
Sbjct: 112 ELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPIT 170
Query: 146 RVLQNTEPAAFKQYFFTWRD 87
V Q EP +F +F W D
Sbjct: 171 VVKQGFEPPSFVGWFLGWDD 190
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 58.0 bits (134), Expect = 4e-08
Identities = 34/122 (27%), Positives = 64/122 (52%)
Frame = -1
Query: 824 FXSYFQTPLTYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCF 645
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ F
Sbjct: 577 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 635
Query: 644 VLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTA 465
+L DIYV+ G +A KA FA ++ + G+ ++ ++ ++ +F+ A
Sbjct: 636 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 692
Query: 464 LG 459
LG
Sbjct: 693 LG 694
Score = 37.1 bits (82), Expect = 0.077
Identities = 25/77 (32%), Positives = 40/77 (51%)
Frame = -1
Query: 344 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYP 165
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +N
Sbjct: 617 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 672
Query: 164 SWVQVTRVLQNTEPAAF 114
++T ++Q E F
Sbjct: 673 GKAEITLLVQGQELPEF 689
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 57.6 bits (133), Expect = 5e-08
Identities = 30/66 (45%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Frame = -1
Query: 827 LFXSYFQTPLTYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGD 651
LF SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGD 164
Query: 650 CFVLSL 633
CF+L L
Sbjct: 165 CFILDL 170
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = -1
Query: 731 RMFQVKGKRD--VRVRQVDPQIASMNKGDCFVLSL-DNDIYVFVGEKAKNVEKLKAISFA 561
R+FQV+ R+ +VD S+N D FVL L N Y++VG+ A E+ A A
Sbjct: 192 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 251
Query: 560 NQVRDQDHHGRGKVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 381
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 252 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 296
Query: 380 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 201
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 297 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 353
Query: 200 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 93
A+ L + + + Q EP F +F W
Sbjct: 354 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 391
>AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant
protein.
Length = 326
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 317 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQV 150
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 194 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 248
Query: 149 TRVLQNTEPAAFKQYFFTW 93
V Q EP F +FFTW
Sbjct: 249 VLVKQGHEPPTFIGWFFTW 267
>DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein.
Length = 1553
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein.
Length = 846
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor
potential-related channel 7, a novel putative Ca2+
channel p protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation
channel protein.
Length = 1449
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2,
striatum sh protein.
Length = 1289
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 197 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 240
>AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2, long
form ( protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.9
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 384 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 256
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3,
precursor protein.
Length = 956
Score = 30.3 bits (65), Expect = 8.9
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = -1
Query: 689 QVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHG 531
Q+DP +N+G V ++++D + VG A N + AN V D D+ G
Sbjct: 741 QIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHANTVTDDDYAG 793
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,214,103
Number of Sequences: 237096
Number of extensions: 2273288
Number of successful extensions: 5058
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 4779
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5012
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10370898348
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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