Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_pT_D14
(809 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 181 2e-45
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 180 4e-45
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 180 4e-45
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 180 4e-45
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 180 4e-45
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 165 2e-40
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 151 2e-36
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 8.6
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 8.6
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 8.6
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 181 bits (441), Expect = 2e-45
Identities = 95/251 (37%), Positives = 135/251 (53%), Gaps = 1/251 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 103 DDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 161
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 162 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 221
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 222 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 281
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 282 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 341
Query: 90 KKLLDITYNRQ 58
L Y R+
Sbjct: 342 LGLARKIYKRR 352
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 180 bits (439), Expect = 4e-45
Identities = 95/251 (37%), Positives = 135/251 (53%), Gaps = 1/251 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 96 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 154
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 155 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 214
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 215 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 274
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 275 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 334
Query: 90 KKLLDITYNRQ 58
L Y R+
Sbjct: 335 LGLARKIYKRR 345
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 180 bits (439), Expect = 4e-45
Identities = 95/251 (37%), Positives = 135/251 (53%), Gaps = 1/251 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 170 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 228
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 229 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 288
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 289 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 348
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 349 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 408
Query: 90 KKLLDITYNRQ 58
L Y R+
Sbjct: 409 LGLARKIYKRR 419
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 180 bits (439), Expect = 4e-45
Identities = 95/251 (37%), Positives = 135/251 (53%), Gaps = 1/251 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 169 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 227
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 228 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 287
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 407
Query: 90 KKLLDITYNRQ 58
L Y R+
Sbjct: 408 LGLARKIYKRR 418
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 180 bits (439), Expect = 4e-45
Identities = 95/251 (37%), Positives = 135/251 (53%), Gaps = 1/251 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 169 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 227
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 228 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 287
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 407
Query: 90 KKLLDITYNRQ 58
L Y R+
Sbjct: 408 LGLARKIYKRR 418
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 165 bits (400), Expect = 2e-40
Identities = 91/250 (36%), Positives = 126/250 (50%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S RG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF
Sbjct: 98 DDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYLNLIELFL 156
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
++ + T +GQ LD +T + D FT R LP++ V
Sbjct: 157 QSSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAAAXXXXGIVX 216
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
EK + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L VQ L R T
Sbjct: 217 EKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRATPE 276
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 91
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 277 QYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 336
Query: 90 KKLLDITYNR 61
L Y R
Sbjct: 337 LGLARQIYKR 346
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 151 bits (367), Expect = 2e-36
Identities = 81/229 (35%), Positives = 121/229 (52%), Gaps = 1/229 (0%)
Frame = -3
Query: 807 DDIMDGSSVXRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFN 628
DDIMD S +G WY++ +G+ A D++L+ + ++ K R P Y+ + ELF
Sbjct: 71 DDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYLNLMELFQ 129
Query: 627 ETLWSTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 451
+ + T +GQ LD +T + D T R + LPV+ + ++ D
Sbjct: 130 QNSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAAAMYMSRMDD 189
Query: 450 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 271
+K + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+WL VQ L + T
Sbjct: 190 KKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVVQCLLQATPE 249
Query: 270 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 124
Q + K Y E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 250 QYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 8.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 341 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 249
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 341 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 249
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 341 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 249
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,619,812
Number of Sequences: 237096
Number of extensions: 2300150
Number of successful extensions: 4247
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4233
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10036353240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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