Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_pT_A07
(846 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 117 5e-26
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 117 5e-26
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 117 5e-26
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 117 5e-26
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 117 5e-26
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 103 1e-21
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 103 1e-21
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 9.2
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 9.2
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 9.2
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 117 bits (282), Expect = 5e-26
Identities = 57/131 (43%), Positives = 77/131 (58%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 215 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 274
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 275 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 334
Query: 84 KKLLDITYNRQ 52
L Y R+
Sbjct: 335 LGLARKIYKRR 345
Score = 94.3 bits (224), Expect = 5e-19
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A ND+ L+ + ++ K
Sbjct: 82 GWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYC 140
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R +
Sbjct: 141 REQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFY 200
Query: 487 LPVSLGLLLAENVDEK 440
LP++ + +A EK
Sbjct: 201 LPIAAAMYMAGIDGEK 216
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 117 bits (282), Expect = 5e-26
Identities = 57/131 (43%), Positives = 77/131 (58%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 222 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 281
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 282 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 341
Query: 84 KKLLDITYNRQ 52
L Y R+
Sbjct: 342 LGLARKIYKRR 352
Score = 95.1 bits (226), Expect = 3e-19
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A ND+ L+ + ++ K
Sbjct: 89 GWCVELLQAFFLVADDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYC 147
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R +
Sbjct: 148 REQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFY 207
Query: 487 LPVSLGLLLAENVDEK 440
LP++ + +A EK
Sbjct: 208 LPIAAAMYMAGIDGEK 223
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 117 bits (282), Expect = 5e-26
Identities = 57/131 (43%), Positives = 77/131 (58%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 289 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 348
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 349 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 408
Query: 84 KKLLDITYNRQ 52
L Y R+
Sbjct: 409 LGLARKIYKRR 419
Score = 94.3 bits (224), Expect = 5e-19
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A ND+ L+ + ++ K
Sbjct: 156 GWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYC 214
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R +
Sbjct: 215 REQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFY 274
Query: 487 LPVSLGLLLAENVDEK 440
LP++ + +A EK
Sbjct: 275 LPIAAAMYMAGIDGEK 290
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 117 bits (282), Expect = 5e-26
Identities = 57/131 (43%), Positives = 77/131 (58%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 407
Query: 84 KKLLDITYNRQ 52
L Y R+
Sbjct: 408 LGLARKIYKRR 418
Score = 94.3 bits (224), Expect = 5e-19
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A ND+ L+ + ++ K
Sbjct: 155 GWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYC 213
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R +
Sbjct: 214 REQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFY 273
Query: 487 LPVSLGLLLAENVDEK 440
LP++ + +A EK
Sbjct: 274 LPIAAAMYMAGIDGEK 289
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 117 bits (282), Expect = 5e-26
Identities = 57/131 (43%), Positives = 77/131 (58%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 407
Query: 84 KKLLDITYNRQ 52
L Y R+
Sbjct: 408 LGLARKIYKRR 418
Score = 94.3 bits (224), Expect = 5e-19
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A ND+ L+ + ++ K
Sbjct: 155 GWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYC 213
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R +
Sbjct: 214 REQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFY 273
Query: 487 LPVSLGLLLAENVDEK 440
LP++ + +A EK
Sbjct: 274 LPIAAAMYMAGIDGEK 289
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 103 bits (246), Expect = 1e-21
Identities = 53/130 (40%), Positives = 71/130 (54%)
Frame = -1
Query: 444 KKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 265
+K + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L VQ L R T
Sbjct: 217 EKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRATPE 276
Query: 264 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLF 85
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 277 QYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVF 336
Query: 84 KKLLDITYNR 55
L Y R
Sbjct: 337 LGLARQIYKR 346
Score = 91.1 bits (216), Expect = 5e-18
Identities = 47/136 (34%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GWCVE+ QA+ +V DDIMD S RG CWY++P VG+ A +D+ L+ + ++ K
Sbjct: 84 GWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYC 142
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF ++ ++T +GQ LD +T + D FT R
Sbjct: 143 REQPYYLNLIELFLQSSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSY 202
Query: 487 LPVSLGLLLAENVDEK 440
LP++ V EK
Sbjct: 203 LPIAAAXXXXGIVXEK 218
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 103 bits (246), Expect = 1e-21
Identities = 52/122 (42%), Positives = 69/122 (56%)
Frame = -1
Query: 483 PFPLVYY*LKMWMKKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 304
P Y +M KK + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+
Sbjct: 177 PVAAAMYMSRMDDKKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCS 236
Query: 303 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 124
WL VQ L + T Q + K Y E V R+K LYE+L LP ++ EK Y +++
Sbjct: 237 WLVVQCLLQATPEQYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGL 296
Query: 123 IE 118
IE
Sbjct: 297 IE 298
Score = 75.8 bits (178), Expect = 2e-13
Identities = 40/136 (29%), Positives = 69/136 (50%), Gaps = 1/136 (0%)
Frame = -3
Query: 844 GWCVEMFQAYCIVXDDIMDGSSVXRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFXKTNF 665
GW ++ QA+ +V DDIMD S +G WY++ +G+ A ND++L+ + ++ K
Sbjct: 57 GWYAQLLQAFFLVADDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYC 115
Query: 664 RTNPNYIKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYN 488
R P Y+ + ELF + ++T +GQ LD +T + D T R +
Sbjct: 116 REQPYYLNLMELFQQNSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFY 175
Query: 487 LPVSLGLLLAENVDEK 440
LPV+ + ++ D+K
Sbjct: 176 LPVAAAMYMSRMDDKK 191
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 9.2
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 335 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 243
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 9.2
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 335 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 243
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 9.2
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 335 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 243
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,659,355
Number of Sequences: 237096
Number of extensions: 2488701
Number of successful extensions: 4274
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4142
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4267
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10705443456
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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