Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_N18
(855 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY290821-1|AAP42280.1| 348|Homo sapiens LYK5 protein protein. 174 3e-43
AK075005-1|BAC11349.1| 348|Homo sapiens protein ( Homo sapiens ... 174 3e-43
AK074771-1|BAC11197.1| 394|Homo sapiens protein ( Homo sapiens ... 174 3e-43
AF308302-1|AAG48269.1| 431|Homo sapiens serologically defined b... 174 3e-43
BC043641-1|AAH43641.1| 234|Homo sapiens LYK5 protein protein. 164 4e-40
BC090871-1|AAH90871.1| 377|Homo sapiens ALS2CR2 protein protein. 138 2e-32
BC008302-1|AAH08302.1| 418|Homo sapiens amyotrophic lateral scl... 138 2e-32
AY093697-1|AAM19143.1| 418|Homo sapiens ILP-interacting protein... 138 2e-32
AK027637-1|BAB55254.1| 418|Homo sapiens protein ( Homo sapiens ... 138 2e-32
AC007282-3|AAY14692.1| 418|Homo sapiens unknown protein. 138 2e-32
AB038950-1|BAB32500.1| 418|Homo sapiens amyotrophic lateral scl... 138 2e-32
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 120 9e-27
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 120 9e-27
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 120 9e-27
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 109 2e-23
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 109 2e-23
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 107 5e-23
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 100 1e-20
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 90 1e-17
AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-li... 86 2e-16
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 85 2e-16
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 85 4e-16
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 85 4e-16
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 85 4e-16
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 85 4e-16
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 85 4e-16
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 85 4e-16
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 85 4e-16
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 85 4e-16
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 85 4e-16
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 85 4e-16
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 84 5e-16
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 84 5e-16
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 84 5e-16
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 84 5e-16
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 84 7e-16
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 84 7e-16
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 84 7e-16
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 84 7e-16
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 83 9e-16
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 83 9e-16
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 83 1e-15
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 83 1e-15
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 83 1e-15
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 83 1e-15
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 83 1e-15
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 83 1e-15
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 83 1e-15
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 83 1e-15
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 82 2e-15
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 82 2e-15
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 82 2e-15
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 82 2e-15
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 82 2e-15
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 82 2e-15
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 82 2e-15
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 82 2e-15
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 82 2e-15
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 82 2e-15
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 82 2e-15
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 82 2e-15
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 82 2e-15
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 82 2e-15
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 81 4e-15
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 81 5e-15
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 79 2e-14
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 78 5e-14
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 75 3e-13
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 75 3e-13
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 75 3e-13
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 75 3e-13
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 75 3e-13
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 75 3e-13
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 75 4e-13
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 75 4e-13
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 74 6e-13
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 74 6e-13
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 74 6e-13
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 74 6e-13
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 74 6e-13
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 74 6e-13
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 74 6e-13
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 74 6e-13
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 74 6e-13
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 74 6e-13
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 74 6e-13
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 74 6e-13
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 74 6e-13
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 74 6e-13
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 74 6e-13
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 74 6e-13
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 74 8e-13
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 74 8e-13
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 74 8e-13
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 73 1e-12
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 73 1e-12
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 73 1e-12
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 73 1e-12
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 73 1e-12
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 73 1e-12
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 72 2e-12
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 72 2e-12
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 71 5e-12
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 71 7e-12
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 71 7e-12
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 71 7e-12
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 71 7e-12
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 71 7e-12
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 71 7e-12
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 71 7e-12
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 71 7e-12
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 71 7e-12
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 71 7e-12
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 71 7e-12
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 71 7e-12
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 71 7e-12
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 71 7e-12
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 71 7e-12
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 71 7e-12
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 71 7e-12
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 71 7e-12
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 71 7e-12
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 71 7e-12
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 70 9e-12
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 69 2e-11
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 69 2e-11
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 69 2e-11
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 69 2e-11
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 69 2e-11
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 69 3e-11
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 69 3e-11
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 69 3e-11
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 69 3e-11
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 69 3e-11
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 68 5e-11
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 68 5e-11
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 68 5e-11
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 68 5e-11
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 68 5e-11
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 67 7e-11
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 67 7e-11
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 67 7e-11
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 67 7e-11
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 67 7e-11
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 67 7e-11
AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein. 67 7e-11
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 66 1e-10
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 66 1e-10
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 66 1e-10
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 66 1e-10
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 66 1e-10
AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinas... 66 1e-10
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 66 1e-10
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 66 1e-10
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 66 1e-10
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 66 1e-10
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 66 1e-10
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 66 1e-10
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 66 2e-10
BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacti... 66 2e-10
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 66 2e-10
AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kin... 66 2e-10
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 66 2e-10
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 66 2e-10
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 66 2e-10
AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK... 66 2e-10
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 66 2e-10
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 65 3e-10
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 65 3e-10
AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein. 65 4e-10
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 64 5e-10
BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein pr... 64 6e-10
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 63 1e-09
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 63 1e-09
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 63 1e-09
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 63 1e-09
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 63 1e-09
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 63 1e-09
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 63 1e-09
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 63 1e-09
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 63 1e-09
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 63 1e-09
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 63 1e-09
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 63 1e-09
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 63 1e-09
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 63 1e-09
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 63 1e-09
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 63 1e-09
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 63 1e-09
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 63 1e-09
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 63 1e-09
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 63 1e-09
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 63 1e-09
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 61 4e-09
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 60 8e-09
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 60 8e-09
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 60 8e-09
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 60 8e-09
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 60 8e-09
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 60 8e-09
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 60 8e-09
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 60 8e-09
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 60 8e-09
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 60 8e-09
AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein. 60 8e-09
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 60 8e-09
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 60 1e-08
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 60 1e-08
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 60 1e-08
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 60 1e-08
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 60 1e-08
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 60 1e-08
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 60 1e-08
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 60 1e-08
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 60 1e-08
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 59 2e-08
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 59 2e-08
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 59 2e-08
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 59 2e-08
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 59 2e-08
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 59 2e-08
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 59 2e-08
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 59 2e-08
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 59 2e-08
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 59 2e-08
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 59 2e-08
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 59 2e-08
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 58 3e-08
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 58 3e-08
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 58 3e-08
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 58 3e-08
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 58 3e-08
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 58 3e-08
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 58 3e-08
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 58 3e-08
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 58 3e-08
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 58 3e-08
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 58 5e-08
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 58 5e-08
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 58 5e-08
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 58 5e-08
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 58 5e-08
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 58 5e-08
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 58 5e-08
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 58 5e-08
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 58 5e-08
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 58 5e-08
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 57 7e-08
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 57 7e-08
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 57 7e-08
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 57 7e-08
AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis ... 57 7e-08
AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis... 57 7e-08
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 57 7e-08
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 57 7e-08
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 57 9e-08
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 57 9e-08
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 57 9e-08
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 57 9e-08
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 57 9e-08
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 57 9e-08
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 57 9e-08
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 57 9e-08
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 57 9e-08
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 57 9e-08
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 57 9e-08
BC112933-1|AAI12934.1| 387|Homo sapiens EPHA10 protein protein. 56 2e-07
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 56 2e-07
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 55 3e-07
AY834276-1|AAV97884.1| 1042|Homo sapiens mitogen-activated prote... 55 3e-07
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 55 4e-07
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 55 4e-07
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 55 4e-07
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 55 4e-07
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 55 4e-07
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 55 4e-07
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 54 5e-07
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 54 5e-07
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 54 5e-07
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 54 5e-07
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 54 5e-07
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 54 5e-07
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 54 5e-07
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 54 5e-07
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 54 5e-07
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 54 5e-07
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 54 5e-07
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 54 5e-07
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 54 5e-07
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 54 5e-07
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 54 5e-07
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 54 5e-07
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 54 5e-07
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 54 5e-07
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 54 5e-07
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 54 5e-07
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 54 5e-07
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 54 5e-07
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 54 5e-07
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 54 5e-07
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 54 5e-07
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 54 5e-07
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 54 5e-07
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 54 5e-07
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 54 5e-07
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 54 5e-07
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 54 5e-07
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 54 7e-07
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 54 7e-07
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 54 7e-07
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 54 7e-07
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 54 7e-07
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 54 7e-07
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 54 7e-07
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 54 7e-07
BC034417-1|AAH34417.1| 168|Homo sapiens YSK4 protein protein. 54 7e-07
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 54 7e-07
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 54 7e-07
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 54 7e-07
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 54 7e-07
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 54 7e-07
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 54 7e-07
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 54 7e-07
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 54 7e-07
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 54 7e-07
AC016725-3|AAY14999.1| 168|Homo sapiens unknown protein. 54 7e-07
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 54 9e-07
AK026727-1|BAB15538.1| 168|Homo sapiens protein ( Homo sapiens ... 53 2e-06
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 52 2e-06
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 52 2e-06
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 52 2e-06
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 52 2e-06
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 52 2e-06
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 52 2e-06
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 52 2e-06
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 52 2e-06
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 52 2e-06
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 52 2e-06
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 52 2e-06
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 52 2e-06
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 52 3e-06
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 52 3e-06
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 52 3e-06
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 52 3e-06
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 52 3e-06
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 52 3e-06
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 52 3e-06
AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis... 52 4e-06
AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis... 52 4e-06
AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis ... 52 4e-06
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 52 4e-06
D45906-1|BAA08312.1| 638|Homo sapiens LIMK-2 protein. 51 5e-06
CR456513-1|CAG30399.1| 638|Homo sapiens LIMK2 protein. 51 5e-06
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 51 5e-06
BC013051-1|AAH13051.1| 686|Homo sapiens LIM domain kinase 2 pro... 51 5e-06
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 51 5e-06
AC002073-3|AAB54055.1| 733|Homo sapiens Lim kinase protein. 51 5e-06
AC002073-2|AAB54056.1| 638|Homo sapiens Lim Kinase protein. 51 5e-06
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 51 5e-06
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 51 6e-06
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 51 6e-06
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 51 6e-06
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 51 6e-06
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 51 6e-06
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 51 6e-06
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 51 6e-06
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 51 6e-06
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 51 6e-06
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 51 6e-06
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 51 6e-06
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 51 6e-06
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 51 6e-06
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 51 6e-06
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 51 6e-06
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 51 6e-06
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 51 6e-06
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 51 6e-06
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 51 6e-06
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 51 6e-06
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 6e-06
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 51 6e-06
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 51 6e-06
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 51 6e-06
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 51 6e-06
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 51 6e-06
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 51 6e-06
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 51 6e-06
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 51 6e-06
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 51 6e-06
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 51 6e-06
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 51 6e-06
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 6e-06
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 51 6e-06
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 51 6e-06
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 51 6e-06
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 51 6e-06
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 51 6e-06
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 51 6e-06
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 51 6e-06
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 51 6e-06
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 50 8e-06
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 50 8e-06
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 50 8e-06
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 50 8e-06
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 50 1e-05
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 50 1e-05
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 50 1e-05
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 50 1e-05
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 50 1e-05
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 50 1e-05
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 50 1e-05
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 50 1e-05
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 50 1e-05
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 50 1e-05
BC040526-1|AAH40526.1| 1497|Homo sapiens TEX14 protein protein. 50 1e-05
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 50 1e-05
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 50 1e-05
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 50 1e-05
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 50 1e-05
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 50 1e-05
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 50 1e-05
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 50 1e-05
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 50 1e-05
U31601-1|AAC50226.1| 1094|Homo sapiens JAK3B protein. 49 2e-05
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 49 2e-05
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 49 2e-05
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 49 2e-05
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 48 3e-05
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 48 3e-05
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 48 3e-05
Y12337-1|CAA73006.1| 289|Homo sapiens myotonic dystrophy protei... 48 3e-05
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 48 3e-05
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 48 3e-05
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 48 3e-05
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 48 3e-05
L37378-1|AAA74451.1| 1108|Homo sapiens guanylyl cyclase protein. 48 3e-05
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 48 3e-05
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 48 3e-05
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 48 3e-05
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 48 3e-05
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 48 3e-05
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 48 3e-05
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 48 3e-05
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 48 3e-05
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 48 3e-05
AL031387-4|CAB41303.1| 1108|Homo sapiens guanylate cyclase 2F, r... 48 3e-05
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 48 3e-05
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 48 3e-05
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 48 3e-05
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 48 3e-05
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 48 3e-05
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 48 3e-05
Z25426-1|CAA80913.1| 113|Homo sapiens protein-serine/threonine ... 48 4e-05
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 48 4e-05
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 48 4e-05
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 48 4e-05
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 48 4e-05
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 48 4e-05
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 48 4e-05
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 48 4e-05
BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein. 48 4e-05
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 48 4e-05
>AY290821-1|AAP42280.1| 348|Homo sapiens LYK5 protein protein.
Length = 348
Score = 174 bits (424), Expect = 3e-43
Identities = 90/222 (40%), Positives = 135/222 (60%), Gaps = 1/222 (0%)
Frame = +1
Query: 163 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 339
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 27 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 87 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 146
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H P + L
Sbjct: 147 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDF--PKYSVKVL 204
Query: 700 MWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
WLSPEVL+QNL+GYD +SDIYS G+ P + P
Sbjct: 205 PWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMP 246
Score = 34.3 bits (75), Expect = 0.57
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 779 SACELANGAVPFAEVPTTLMFTXKV 853
+ACELANG VPF ++P T M K+
Sbjct: 231 TACELANGHVPFKDMPATQMLLEKL 255
>AK075005-1|BAC11349.1| 348|Homo sapiens protein ( Homo sapiens
cDNA FLJ90524 fis, clone NT2RP4000962, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 348
Score = 174 bits (424), Expect = 3e-43
Identities = 90/222 (40%), Positives = 135/222 (60%), Gaps = 1/222 (0%)
Frame = +1
Query: 163 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 339
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 27 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 87 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 146
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H P + L
Sbjct: 147 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDF--PKYSVKVL 204
Query: 700 MWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
WLSPEVL+QNL+GYD +SDIYS G+ P + P
Sbjct: 205 PWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMP 246
Score = 34.3 bits (75), Expect = 0.57
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 779 SACELANGAVPFAEVPTTLMFTXKV 853
+ACELANG VPF ++P T M K+
Sbjct: 231 TACELANGHVPFKDMPATQMLLEKL 255
>AK074771-1|BAC11197.1| 394|Homo sapiens protein ( Homo sapiens
cDNA FLJ90290 fis, clone NT2RP1001020, weakly similar to
SERINE/THREONINE-PROTEIN KINASE PAK-BETA (EC 2.7.1.-).
).
Length = 394
Score = 174 bits (424), Expect = 3e-43
Identities = 90/222 (40%), Positives = 135/222 (60%), Gaps = 1/222 (0%)
Frame = +1
Query: 163 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 339
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 27 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 87 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 146
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H P + L
Sbjct: 147 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDF--PKYSVKVL 204
Query: 700 MWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
WLSPEVL+QNL+GYD +SDIYS G+ P + P
Sbjct: 205 PWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMP 246
Score = 34.3 bits (75), Expect = 0.57
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 779 SACELANGAVPFAEVPTTLMFTXKV 853
+ACELANG VPF ++P T M K+
Sbjct: 231 TACELANGHVPFKDMPATQMLLEKL 255
>AF308302-1|AAG48269.1| 431|Homo sapiens serologically defined
breast cancer antigen NY-BR-96 protein.
Length = 431
Score = 174 bits (424), Expect = 3e-43
Identities = 90/222 (40%), Positives = 135/222 (60%), Gaps = 1/222 (0%)
Frame = +1
Query: 163 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 339
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 64 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 123
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 124 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 183
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H P + L
Sbjct: 184 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDF--PKYSVKVL 241
Query: 700 MWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
WLSPEVL+QNL+GYD +SDIYS G+ P + P
Sbjct: 242 PWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMP 283
Score = 34.3 bits (75), Expect = 0.57
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 779 SACELANGAVPFAEVPTTLMFTXKV 853
+ACELANG VPF ++P T M K+
Sbjct: 268 TACELANGHVPFKDMPATQMLLEKL 292
>BC043641-1|AAH43641.1| 234|Homo sapiens LYK5 protein protein.
Length = 234
Score = 164 bits (398), Expect = 4e-40
Identities = 88/222 (39%), Positives = 132/222 (59%), Gaps = 1/222 (0%)
Frame = +1
Query: 163 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 339
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 6 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 65
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 66 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 125
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H P + L
Sbjct: 126 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDF--PKYSVKVL 183
Query: 700 MWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
WLSPEVL+Q GYD +SDIYS G+ P + P
Sbjct: 184 PWLSPEVLQQ---GYDAKSDIYSVGITACELANGHVPFKDMP 222
Score = 31.5 bits (68), Expect = 4.0
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = +2
Query: 779 SACELANGAVPFAEVPTT 832
+ACELANG VPF ++P T
Sbjct: 207 TACELANGHVPFKDMPAT 224
>BC090871-1|AAH90871.1| 377|Homo sapiens ALS2CR2 protein protein.
Length = 377
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>BC008302-1|AAH08302.1| 418|Homo sapiens amyotrophic lateral
sclerosis 2 (juvenile) chromosome region, candidate 2
protein.
Length = 418
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AY093697-1|AAM19143.1| 418|Homo sapiens ILP-interacting protein
ILPIPA protein.
Length = 418
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AK027637-1|BAB55254.1| 418|Homo sapiens protein ( Homo sapiens
cDNA FLJ14731 fis, clone NT2RP3001938, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 418
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AC007282-3|AAY14692.1| 418|Homo sapiens unknown protein.
Length = 418
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AB038950-1|BAB32500.1| 418|Homo sapiens amyotrophic lateral
sclerosis 2 protein.
Length = 418
Score = 138 bits (334), Expect = 2e-32
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 3/214 (1%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKE 342
+++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 54 NVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHF 113
Query: 343 LHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQ 522
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L ++ L
Sbjct: 114 FRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLN 173
Query: 523 YLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLM 702
YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++ P +
Sbjct: 174 YLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDF--PQFSTSVQP 231
Query: 703 WLSPEVLEQNLKGYDERSDIYSFGVLC--LRTGQ 798
WLSPE+L Q+L GY+ +SDIYS G+ L +GQ
Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 120 bits (288), Expect = 9e-27
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 10/228 (4%)
Frame = +1
Query: 172 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 351
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 513
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 514 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPD 681
L+YLHK IHR V+A ++L+G +G +++ +A + G + RK + P
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTP-- 190
Query: 682 HDNANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++DI+SFG+ + P + P
Sbjct: 191 ------CWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYP 231
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 120 bits (288), Expect = 9e-27
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 10/228 (4%)
Frame = +1
Query: 172 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 351
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 513
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 514 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPD 681
L+YLHK IHR V+A ++L+G +G +++ +A + G + RK + P
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTP-- 190
Query: 682 HDNANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++DI+SFG+ + P + P
Sbjct: 191 ------CWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYP 231
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 120 bits (288), Expect = 9e-27
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 10/228 (4%)
Frame = +1
Query: 172 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 351
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 513
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 514 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPD 681
L+YLHK IHR V+A ++L+G +G +++ +A + G + RK + P
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTP-- 190
Query: 682 HDNANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++DI+SFG+ + P + P
Sbjct: 191 ------CWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYP 231
>AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase SPAK
protein.
Length = 547
Score = 109 bits (261), Expect = 2e-23
Identities = 68/226 (30%), Positives = 118/226 (52%), Gaps = 10/226 (4%)
Frame = +1
Query: 178 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 357
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 65 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 122
Query: 358 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 519
++ Y SFV EL++V L+S GS DI+ G + E A +L++VL+ L
Sbjct: 123 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 182
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPDHD 687
YLH+ IHR ++A ++L+G +G +++ +A + G + RK + P
Sbjct: 183 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP---- 238
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++D++SFG+ + P + P
Sbjct: 239 ----CWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAAPYHKYP 279
>AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein.
Length = 363
Score = 109 bits (261), Expect = 2e-23
Identities = 68/226 (30%), Positives = 118/226 (52%), Gaps = 10/226 (4%)
Frame = +1
Query: 178 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 357
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 63 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 120
Query: 358 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 519
++ Y SFV EL++V L+S GS DI+ G + E A +L++VL+ L
Sbjct: 121 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 180
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPDHD 687
YLH+ IHR ++A ++L+G +G +++ +A + G + RK + P
Sbjct: 181 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP---- 236
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++D++SFG+ + P + P
Sbjct: 237 ----CWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAAPYHKYP 277
>AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kinase
protein.
Length = 547
Score = 107 bits (257), Expect = 5e-23
Identities = 67/226 (29%), Positives = 117/226 (51%), Gaps = 10/226 (4%)
Frame = +1
Query: 178 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 357
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 65 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 122
Query: 358 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 519
++ Y SFV EL++V L+S GS DI+ G + E A + ++VL+ L
Sbjct: 123 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATIFKEVLEGL 182
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPDHD 687
YLH+ IHR ++A ++L+G +G +++ +A + G + RK + P
Sbjct: 183 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP---- 238
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
W++PEV+EQ ++GYD ++D++SFG+ + P + P
Sbjct: 239 ----CWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAAPYHKYP 279
>AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein.
Length = 467
Score = 99.5 bits (237), Expect = 1e-20
Identities = 58/178 (32%), Positives = 95/178 (53%), Gaps = 10/178 (5%)
Frame = +1
Query: 322 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELA 483
++ + HH NI+ Y SFV EL++V L+S GS DI+ +G + E
Sbjct: 3 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 62
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQ 651
A +LR+VL+ L+YLHK IHR V+A ++L+G +G +++ +A + G +
Sbjct: 63 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 122
Query: 652 RKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSP 825
RK + P W++PEV+EQ ++GYD ++DI+SFG+ + P + P
Sbjct: 123 RKTFVGTP--------CWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYP 171
>U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor
kinase protein.
Length = 833
Score = 89.8 bits (213), Expect = 1e-17
Identities = 61/197 (30%), Positives = 99/197 (50%), Gaps = 1/197 (0%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ A K + VA+K ++ + +TL Q+++L K HANI+ Y S++ ++L++
Sbjct: 31 VFKARDKVSGDLVALKMVKMEPDDDVSTL-QKEILILKTCRHANIVAYHGSYLWLQKLWI 89
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
GS +DI +SEL + V R+VLQ L YLH Q IHR ++ +++LI
Sbjct: 90 CMEFCGAGSLQDIYQ--VTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILIND 147
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-GYDERSDI 762
G RL+ S + R+L + P W++PEV LK GY+E DI
Sbjct: 148 AGEVRLADF--GISAQIGATLARRLSFIGTP-------YWMAPEVAAVALKGGYNELCDI 198
Query: 763 YSFGVLCLRTGQRGGPV 813
+S G+ + + P+
Sbjct: 199 WSLGITAIELAELQPPL 215
>AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-like
kinase protein.
Length = 476
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/183 (30%), Positives = 94/183 (51%), Gaps = 10/183 (5%)
Frame = +1
Query: 208 SDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVH 387
S AVV +AL KP +VAIKR +++ + + +++ + H N++ Y SFV
Sbjct: 22 SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVV 81
Query: 388 GRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQALQYLHKQLYIH 549
EL++V L+S GS DI+ G + E A +L++VL+ L YLH+ IH
Sbjct: 82 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 141
Query: 550 RSVRASHVLIGANGVARLSGLRTAASMMVRG----QRQRKLHLLPPPDHDNANLMWLSPE 717
R ++A ++L+G +G +++ +A + G + RK + P W++PE
Sbjct: 142 RDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTP--------CWMAPE 193
Query: 718 VLE 726
V+E
Sbjct: 194 VME 196
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/201 (25%), Positives = 100/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ + A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADI-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 84.6 bits (200), Expect = 4e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V++A +VAIK+ + + + K LI ++L KEL + NI+ +L S++ G EL+V
Sbjct: 263 VFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 321
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ +VL+G
Sbjct: 322 VMEYLAGGSLTDVVTE--TACMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGM 379
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 380 EGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 428
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 429 SLGIMAI 435
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 215
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 216 SLGITAIELA-RGEPPHSELH 235
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 215
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 216 SLGITAIELA-RGEPPHSELH 235
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 215
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 216 SLGITAIELA-RGEPPHSELH 235
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/201 (25%), Positives = 99/201 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIKQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPH 828
S G+ + RG P H
Sbjct: 204 SLGITAIELA-RGEPPHSELH 223
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/187 (28%), Positives = 102/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+A+ +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 342
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ ++L+G
Sbjct: 343 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGM 399
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 400 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 448
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 449 SLGIMAI 455
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/187 (28%), Positives = 102/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+A+ +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 342
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ ++L+G
Sbjct: 343 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGM 399
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 400 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 448
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 449 SLGIMAI 455
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V++A +VAIK+ + + + K LI ++L KEL + NI+ +L S++ G EL+V
Sbjct: 263 VFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 321
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ +VL+G
Sbjct: 322 VMEYLAGGSLTDVVTETC---MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGM 378
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 379 EGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 427
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 428 SLGIMAI 434
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/187 (28%), Positives = 102/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+A+ +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 342
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ ++L+G
Sbjct: 343 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGM 399
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 400 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 448
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 449 SLGIMAI 455
>AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 282 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 340
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 341 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 397
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 398 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 446
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 447 SLGIMAI 453
>AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 297 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 355
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 356 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 412
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 413 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 461
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 462 SLGIMAI 468
>AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 282 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 340
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 341 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 397
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 398 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 446
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 447 SLGIMAI 453
>AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 297 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 355
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 356 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 412
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 413 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 461
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 462 SLGIMAI 468
>AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 282 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 340
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 341 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 397
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 398 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 446
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 447 SLGIMAI 453
>AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 297 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 355
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 356 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 412
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 413 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 461
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 462 SLGIMAI 468
>AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3
protein.
Length = 544
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 282 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 340
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 341 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 397
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 398 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 446
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 447 SLGIMAI 453
>AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3
protein.
Length = 544
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 282 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 340
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 341 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 397
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 398 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 446
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 447 SLGIMAI 453
>AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3
protein.
Length = 559
Score = 83.8 bits (198), Expect = 7e-16
Identities = 55/187 (29%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+AL +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 297 VYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 355
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL +LH IHR +++ ++L+G
Sbjct: 356 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 412
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 413 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 461
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 462 SLGIMAI 468
>U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein.
Length = 846
Score = 83.4 bits (197), Expect = 9e-16
Identities = 58/205 (28%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N A+K ++ G + +LIQQ++ KE H NI+ Y S++
Sbjct: 27 GSGTYGDVYKARNVHTGELAAVKIIKLEPGDD-FSLIQQEIFMVKECKHCNIVAYFGSYL 85
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 86 SREKLWICMEYCGGGSLQDIYHVTGP--LSELQIAYVCRETLQGLAYLHTKGKMHRDIKG 143
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV--LEQNLK 738
+++L+ +G +L+ AA + +++ P W++PEV +E+N
Sbjct: 144 ANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTP---------YWMAPEVAAVEKN-G 193
Query: 739 GYDERSDIYSFGVLCLRTGQRGGPV 813
GY++ DI++ G+ + G+ P+
Sbjct: 194 GYNQLCDIWAVGITAIELGELQPPM 218
>BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated protein
kinase kinase kinase kinase 5 protein.
Length = 846
Score = 83.4 bits (197), Expect = 9e-16
Identities = 58/205 (28%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N A+K ++ G + +LIQQ++ KE H NI+ Y S++
Sbjct: 27 GSGTYGDVYKARNVHTGELAAVKIIKLEPGDD-FSLIQQEIFMVKECKHCNIVAYFGSYL 85
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 86 SREKLWICMEYCGGGSLQDIYHVTGP--LSELQIAYVCRETLQGLAYLHTKGKMHRDIKG 143
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV--LEQNLK 738
+++L+ +G +L+ AA + +++ P W++PEV +E+N
Sbjct: 144 ANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTP---------YWMAPEVAAVEKN-G 193
Query: 739 GYDERSDIYSFGVLCLRTGQRGGPV 813
GY++ DI++ G+ + G+ P+
Sbjct: 194 GYNQLCDIWAVGITAIELGELQPPM 218
>X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein.
Length = 426
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 107/220 (48%), Gaps = 4/220 (1%)
Frame = +1
Query: 193 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 360
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 361 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 540
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 541 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEV 720
IHR ++A++VL+ G +L+ A + Q +R + P W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEV 186
Query: 721 LEQNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
++Q+ YD ++DI+S G+ + +G P H V
Sbjct: 187 IKQS--AYDFKADIWSLGITAIELA-KGEPPNSDLHPMRV 223
>U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein.
Length = 545
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/187 (28%), Positives = 101/187 (54%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY+A+ +VAIK+ + + + K LI ++L +E + NI+ YL S++ G EL+V
Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQ-QPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 342
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL+ LH IHR +++ ++L+G
Sbjct: 343 VMEYLAGGSLTDVVTETC---MDEGQIAAVCRECLQALESLHSNQVIHRDIKSDNILLGM 399
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
+G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 400 DGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 448
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 449 SLGIMAI 455
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein.
Length = 873
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ NG +L+ +A + +++ P W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTP---------YWMAPEVAAVERKGG 190
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y++ D+++ G+ + + P+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPM 214
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein.
Length = 873
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ NG +L+ +A + +++ P W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTP---------YWMAPEVAAVERKGG 190
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y++ D+++ G+ + + P+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPM 214
>AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein.
Length = 894
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ NG +L+ +A + +++ P W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTP---------YWMAPEVAAVERKGG 190
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y++ D+++ G+ + + P+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPM 214
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase
related protein kinase protein.
Length = 884
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 13 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 71
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 72 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 129
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ NG +L+ +A + +++ P W++PEV K G
Sbjct: 130 ANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTP---------YWMAPEVAAVERKGG 180
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y++ D+++ G+ + + P+
Sbjct: 181 YNQLCDLWAVGITAIELAELQPPM 204
>AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein.
Length = 712
Score = 82.2 bits (194), Expect = 2e-15
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ NG +L+ +A + +++ P W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTP---------YWMAPEVAAVERKGG 190
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y++ D+++ G+ + + P+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPM 214
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/205 (25%), Positives = 100/205 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV++Q+ YD ++DI+
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSKADIW 203
Query: 766 SFGVLCLRTGQRGGPVRRSPHDPHV 840
S G+ + +G P H V
Sbjct: 204 SLGITAIELA-KGEPPNSDMHPMRV 227
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 81.4 bits (192), Expect = 4e-15
Identities = 55/187 (29%), Positives = 100/187 (53%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V++A +VAIK+ + + + K LI ++L KEL + NI+ +L S++ G EL+V
Sbjct: 232 VFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 290
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V M + + R + D + E A V R+ LQAL++LH IHR +++ +VL+G
Sbjct: 291 V---MEYLAGRSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGM 347
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + ++ ++ ++ P W++PEV+ + K Y + DI+
Sbjct: 348 EGSVKLTDFGFCA--QITPEQSKRSTMVGTP-------YWMAPEVVTR--KAYGPKVDIW 396
Query: 766 SFGVLCL 786
S G++ +
Sbjct: 397 SLGIMAI 403
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 81.0 bits (191), Expect = 5e-15
Identities = 56/185 (30%), Positives = 97/185 (52%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V++A KVAIK+ + + + K LI ++L KEL + NI+ +L S++ G EL+V
Sbjct: 21 VFTATDVALGQKVAIKQINLQK-QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 79
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ VL+G
Sbjct: 80 VVEYLARGSLTDVVTETC---MDEAQIAAVCRESLQALEFLHANQVIHRDIKSDSVLLGM 136
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G +L+ A + Q +R + P W++PEV+ + K Y + +++
Sbjct: 137 EGSVKLTDFGFCAQITPE-QSKRSTVIRTP--------YWMAPEVVTR--KAYGPKVNVW 185
Query: 766 SFGVL 780
S G++
Sbjct: 186 SLGIM 190
>BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein.
Length = 812
Score = 79.0 bits (186), Expect = 2e-14
Identities = 52/204 (25%), Positives = 97/204 (47%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
GA Y +YK +T A+K +D G + ++L QQ++ +E H N++ Y+ S++
Sbjct: 23 GAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSL-QQEITILRECRHPNVVAYIGSYL 81
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
L++ GS ++I P + E A V R+ L+ L +LH Q IHR ++
Sbjct: 82 RNDRLWICMEFCGGGSLQEIYHATGP--LEERQIAYVCREALKGLHHLHSQGKIHRDIKG 139
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ G +L+ + + ++R P W++PEV K G
Sbjct: 140 ANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTP---------YWMAPEVAAVERKGG 190
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y+E D+++ G+ + G+ P+
Sbjct: 191 YNELCDVWALGITAIELGELQPPL 214
>U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein.
Length = 819
Score = 77.8 bits (183), Expect = 5e-14
Identities = 52/204 (25%), Positives = 97/204 (47%), Gaps = 5/204 (2%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
GA Y +YK +T A+K +D G + ++L QQ++ +E H N++ Y+ S++
Sbjct: 22 GAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSL-QQEITILRECRHPNVVAYIGSYL 80
Query: 385 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 564
L++ GS ++I P + E A V R+ L+ L +LH Q IHR ++
Sbjct: 81 RNDRLWICMEFCGGGSLQEIYHATGP--LEERQIAYVCRERLKGLHHLHSQGKIHRDIKG 138
Query: 565 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLK-G 741
+++L+ G +L+ + + ++R P W++PEV K G
Sbjct: 139 ANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTP---------YWMAPEVAAVERKGG 189
Query: 742 YDERSDIYSFGVLCLRTGQRGGPV 813
Y+E D+++ G+ + G+ P+
Sbjct: 190 YNELCDVWALGITAIELGELQPPL 213
>BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 462 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 520
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 521 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 577
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 578 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 626
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 627 WSLGIMVI 634
>AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 462 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 520
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 521 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 577
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 578 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 626
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 627 WSLGIMVI 634
>AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 462 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 520
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 521 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 577
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 578 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 626
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 627 WSLGIMVI 634
>AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 462 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 520
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 521 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 577
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 578 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 626
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 627 WSLGIMVI 634
>AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5
protein.
Length = 719
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 462 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 520
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 521 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 577
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 578 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 626
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 627 WSLGIMVI 634
>AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein.
Length = 753
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K +VA+K+ + R +++ L+ +V+ ++ HH N++ +S++ G EL+
Sbjct: 496 IVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELW 554
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VL+AL YLH Q IHR +++ +L+
Sbjct: 555 VVMEFLEGGALTDIVTH---TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLT 611
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
++G +LS A + +++ L P W++PEV+ + Y DI
Sbjct: 612 SDGRIKLSDFGFCAQVSKEVPKRKSLVGTP---------YWMAPEVISR--LPYGTEVDI 660
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 661 WSLGIMVI 668
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/154 (28%), Positives = 80/154 (51%)
Frame = +1
Query: 367 YLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
Y S++ +L+++ + GS D+L+ P + E A +LR++L+ L YLH + I
Sbjct: 2 YYGSYLKDTKLWIIMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKI 58
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLE 726
HR ++A++VL+ +G +L+ A + Q +R + P W++PEV++
Sbjct: 59 HRDIKAANVLLSEHGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIK 109
Query: 727 QNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPH 828
Q+ YD ++DI+S G+ + RG P H
Sbjct: 110 QS--AYDSKADIWSLGITAIELA-RGEPPHSELH 140
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/154 (28%), Positives = 80/154 (51%)
Frame = +1
Query: 367 YLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
Y S++ +L+++ + GS D+L+ P + E A +LR++L+ L YLH + I
Sbjct: 2 YYGSYLKDTKLWIIMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKI 58
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLE 726
HR ++A++VL+ +G +L+ A + Q +R + P W++PEV++
Sbjct: 59 HRDIKAANVLLSEHGEVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIK 109
Query: 727 QNLKGYDERSDIYSFGVLCLRTGQRGGPVRRSPH 828
Q+ YD ++DI+S G+ + RG P H
Sbjct: 110 QS--AYDSKADIWSLGITAIELA-RGEPPHSELH 140
>U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase
kinase kinase 5 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulating
kinase 1 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 227 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 285
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 286 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 345
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 346 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 397
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 398 IWSLGCTVIEMATGR 412
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 227 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 285
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 286 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 345
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 346 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 397
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 398 IWSLGCTVIEMATGR 412
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 130 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 188
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 189 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 248
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 249 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 300
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 301 IWSLGCTVIEMATGR 315
>BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 555 IWSLGCTVIEMATGR 569
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 555 IWSLGCTVIEMATGR 569
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 661 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 719
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 720 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 779
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 780 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 831
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 832 IWSLGCTVIEMATGR 846
>AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 863 DIWSLGCTIIEMATGK 878
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 555 IWSLGCTVIEMATGR 569
>AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 variant protein.
Length = 1455
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 773 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 831
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 832 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 891
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE++++ +GY + +
Sbjct: 892 NTYSGVLKISDFGTS---------KRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 942
Query: 757 DIYSFG--VLCLRTGQ 798
DI+S G ++ + TG+
Sbjct: 943 DIWSLGCTIIEMATGK 958
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 565 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 623
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 624 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 683
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 684 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 735
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 736 IWSLGCTVIEMATGR 750
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regulating
kinase 2 protein.
Length = 1288
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 661 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 719
Query: 403 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 720 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 779
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSD 759
SGL + G +R + P + L +++PE+++Q +GY + +D
Sbjct: 780 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 831
Query: 760 IYSFG--VLCLRTGQ 798
I+S G V+ + TG+
Sbjct: 832 IWSLGCTVIEMATGR 846
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + +++ L P W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSLVGTP---------YWMAPEVISRSL--YATEVDI 584
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 585 WSLGIMVI 592
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + +++ L P W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSLVGTP---------YWMAPEVISRSL--YATEVDI 584
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 585 WSLGIMVI 592
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/188 (27%), Positives = 96/188 (51%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + +++ L P W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSLVGTP---------YWMAPEVISRSL--YATEVDI 584
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 585 WSLGIMVI 592
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 210 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 269
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 270 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 327
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 328 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 374
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 375 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 409
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 73.3 bits (172), Expect = 1e-12
Identities = 58/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 41 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 100
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 101 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 158
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W++
Sbjct: 159 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWMA 205
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 206 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 240
>BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 72.1 bits (169), Expect = 2e-12
Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W +
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWTA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 72.1 bits (169), Expect = 2e-12
Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 4/215 (1%)
Frame = +1
Query: 181 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 351
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 352 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 531
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 532 KQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLS 711
IHR V+A ++L+ G+ +L +A+ ++ P + W +
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSAS-------------IMAPANSFVGTPYWTA 190
Query: 712 PEVLEQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
PEV+ +G YD + D++S G+ C+ +R P+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
>AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 70.9 bits (166), Expect = 5e-12
Identities = 53/199 (26%), Positives = 92/199 (46%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLTYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + PP + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MAPPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKRP 223
>BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein.
Length = 625
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein.
Length = 664
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein.
Length = 247
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein.
Length = 1615
Score = 70.5 bits (165), Expect = 7e-12
Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/195 (24%), Positives = 96/195 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 68 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 124
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 125 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 183
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 184 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 232
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 233 SLGITAIEMAEGKPP 247
>AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ16645 fis, clone TESTI4031745, moderately
similar to Mitogen-activated protein kinase kinase
kinase 5 (EC ).
Length = 788
Score = 70.1 bits (164), Expect = 9e-12
Identities = 46/186 (24%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S L T+ +R + P + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDLGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 757 DIYSFG 774
DI+S G
Sbjct: 308 DIWSLG 313
>BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 69.3 bits (162), Expect = 2e-11
Identities = 64/229 (27%), Positives = 107/229 (46%), Gaps = 12/229 (5%)
Frame = +1
Query: 163 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 339
PD +D +++T I + + G V+ L K N K A+K +D + I+ K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAGYNILK 70
Query: 340 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 495
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 496 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPP 675
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+ +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRRNTSVGT 188
Query: 676 PDHDNANLMWLSPEVL--EQNL-KGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ EQ L YD R D +S G+ + G P+
Sbjct: 189 P-------FWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPL 230
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/176 (25%), Positives = 84/176 (47%), Gaps = 5/176 (2%)
Frame = +1
Query: 262 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 426
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 268 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 327
Query: 427 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 606
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 328 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 385
Query: 607 GLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A + G +L + W++PEV+ N GY +SDI+S G
Sbjct: 386 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 436
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/176 (25%), Positives = 84/176 (47%), Gaps = 5/176 (2%)
Frame = +1
Query: 262 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 426
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 973 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 1032
Query: 427 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 606
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 1033 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 1090
Query: 607 GLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A + G +L + W++PEV+ N GY +SDI+S G
Sbjct: 1091 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 1141
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/176 (25%), Positives = 84/176 (47%), Gaps = 5/176 (2%)
Frame = +1
Query: 262 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 426
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 1086 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 1145
Query: 427 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 606
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 1146 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 1203
Query: 607 GLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A + G +L + W++PEV+ N GY +SDI+S G
Sbjct: 1204 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 1254
>AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protein
kinase MST4a protein.
Length = 354
Score = 69.3 bits (162), Expect = 2e-11
Identities = 45/176 (25%), Positives = 87/176 (49%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDER 753
G +L+ A + Q +R + P W++PEV++Q+ YD +
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--AYDSK 199
>AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 68.5 bits (160), Expect = 3e-11
Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDFGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 757 DIYSFG 774
DI+S G
Sbjct: 308 DIWSLG 313
>AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 68.5 bits (160), Expect = 3e-11
Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDFGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 757 DIYSFG 774
DI+S G
Sbjct: 268 DIWSLG 273
>AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 68.5 bits (160), Expect = 3e-11
Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDFGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 757 DIYSFG 774
DI+S G
Sbjct: 308 DIWSLG 313
>AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 68.5 bits (160), Expect = 3e-11
Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDFGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 757 DIYSFG 774
DI+S G
Sbjct: 268 DIWSLG 273
>AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens
cDNA FLJ16518 fis, clone NT2RI3007443, moderately
similar to MITOGEN-ACTIVATED PROTEIN KINASE KINASE
KINASE 5 (EC ).
Length = 748
Score = 68.5 bits (160), Expect = 3e-11
Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 2/186 (1%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 403 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 580 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+GV ++S T+ +R + P + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDFGTS---------KRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 757 DIYSFG 774
DI+S G
Sbjct: 268 DIWSLG 273
>BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1
(zebrafish) protein.
Length = 1332
Score = 67.7 bits (158), Expect = 5e-11
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 14/213 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 381
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 382 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 543
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 544 IHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL 723
IHR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVI 200
Query: 724 --EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSDI+S G+ + + P+
Sbjct: 201 ACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
>AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related
kinase isoform beta protein.
Length = 1312
Score = 67.7 bits (158), Expect = 5e-11
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 14/213 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 381
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 382 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 543
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 544 IHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL 723
IHR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVI 200
Query: 724 --EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSDI+S G+ + + P+
Sbjct: 201 ACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
>AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase
protein.
Length = 898
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/199 (26%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-2
protein.
Length = 1303
Score = 67.7 bits (158), Expect = 5e-11
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 14/213 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 381
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 382 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 543
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 544 IHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL 723
IHR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVI 200
Query: 724 --EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSDI+S G+ + + P+
Sbjct: 201 ACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
>AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related
kinase MINK-1 protein.
Length = 1295
Score = 67.7 bits (158), Expect = 5e-11
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 14/213 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 381
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 382 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 543
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 544 IHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL 723
IHR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVI 200
Query: 724 --EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSDI+S G+ + + P+
Sbjct: 201 ACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 67.3 bits (157), Expect = 7e-11
Identities = 53/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
N + ++ A R K + DH N W +PE L + Y +SD++
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 766 SFGVLCLRTGQRG 804
SFG+L RG
Sbjct: 372 SFGILLHEMFSRG 384
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 67.3 bits (157), Expect = 7e-11
Identities = 53/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
N + ++ A R K + DH N W +PE L + Y +SD++
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 766 SFGVLCLRTGQRG 804
SFG+L RG
Sbjct: 372 SFGILLHEMFSRG 384
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 67.3 bits (157), Expect = 7e-11
Identities = 47/195 (24%), Positives = 95/195 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 205
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 206 SLGITSIEMAEGKPP 220
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 67.3 bits (157), Expect = 7e-11
Identities = 47/195 (24%), Positives = 95/195 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 205
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 206 SLGITSIEMAEGKPP 220
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 67.3 bits (157), Expect = 7e-11
Identities = 53/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
N + ++ A R K + DH N W +PE L + Y +SD++
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 766 SFGVLCLRTGQRG 804
SFG+L RG
Sbjct: 372 SFGILLHEMFSRG 384
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 67.3 bits (157), Expect = 7e-11
Identities = 47/195 (24%), Positives = 95/195 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P W++PEV+++ GY+ +DI+
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FWMAPEVIQE--IGYNCVADIW 205
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 206 SLGITSIEMAEGKPP 220
>AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein.
Length = 451
Score = 67.3 bits (157), Expect = 7e-11
Identities = 53/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
N + ++ A R K + DH N W +PE L + Y +SD++
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 766 SFGVLCLRTGQRG 804
SFG+L RG
Sbjct: 372 SFGILLHEMFSRG 384
>BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein.
Length = 1001
Score = 66.5 bits (155), Expect = 1e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 160 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 206
Query: 757 DIYSFGVLCLRTGQRGGPV 813
D++S G+ C+ +R P+
Sbjct: 207 DVWSLGITCIELAERKPPL 225
>BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 244 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 302
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 303 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 359
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 360 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 408
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 409 WSLGIMVI 416
>BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 498
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 499 WSLGIMVI 506
>BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 498
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 499 WSLGIMVI 506
>BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 426
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 169 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 227
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 228 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 284
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 285 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 333
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 334 WSLGIMVI 341
>AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinase
transcript variant 5 protein.
Length = 462
Score = 66.5 bits (155), Expect = 1e-10
Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 1/169 (0%)
Frame = +1
Query: 271 KRYFVDRG-KEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDIL 447
K+ F + K + ++ V K L H NI+ YL + + + + + GS I+
Sbjct: 227 KKIFSENSLKSEEPILWTKVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII 286
Query: 448 DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAAS 627
+R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L A
Sbjct: 287 NRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARR 344
Query: 628 MMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG 774
+ G +L + W++PEV+ N GY +SDI+S G
Sbjct: 345 LAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 388
>AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase
TAO1 protein.
Length = 1001
Score = 66.5 bits (155), Expect = 1e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 160 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 206
Query: 757 DIYSFGVLCLRTGQRGGPV 813
D++S G+ C+ +R P+
Sbjct: 207 DVWSLGITCIELAERKPPL 225
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/153 (28%), Positives = 77/153 (50%)
Frame = +1
Query: 382 VHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVR 561
+ G +L+++ + GS D+L R P E A +L+++L+ L YLH + IHR ++
Sbjct: 13 MQGSKLWIIMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIK 69
Query: 562 ASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG 741
A++VL+ G +L+ A + Q +R + P W++PEV++Q+
Sbjct: 70 AANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFVGTP--------FWMAPEVIQQS--A 118
Query: 742 YDERSDIYSFGVLCLRTGQRGGPVRRSPHDPHV 840
YD ++DI+S G+ + +G P H V
Sbjct: 119 YDSKADIWSLGITAIELA-KGEPPNSDMHPMRV 150
>AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein.
Length = 591
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 498
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 499 WSLGIMVI 506
>AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein.
Length = 1001
Score = 66.5 bits (155), Expect = 1e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 160 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 206
Query: 757 DIYSFGVLCLRTGQRGGPV 813
D++S G+ C+ +R P+
Sbjct: 207 DVWSLGITCIELAERKPPL 225
>AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase
protein.
Length = 591
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 498
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 499 WSLGIMVI 506
>AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein.
Length = 1005
Score = 66.5 bits (155), Expect = 1e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 46 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 105
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 106 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 163
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 164 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 210
Query: 757 DIYSFGVLCLRTGQRGGPV 813
D++S G+ C+ +R P+
Sbjct: 211 DVWSLGITCIELAERKPPL 229
>AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein.
Length = 467
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/188 (26%), Positives = 92/188 (48%)
Frame = +1
Query: 223 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 402
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 210 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 268
Query: 403 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 582
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 269 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 325
Query: 583 ANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDI 762
+G +LS A + R++ L P W++PE++ + Y DI
Sbjct: 326 HDGRVKLSDFGFCAQVSKEVPRRKSLVGTP---------YWMAPELISR--LPYGPEVDI 374
Query: 763 YSFGVLCL 786
+S G++ +
Sbjct: 375 WSLGIMVI 382
>BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 65.7 bits (153), Expect = 2e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A + VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacting
kinase protein.
Length = 1360
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein.
Length = 898
Score = 65.7 bits (153), Expect = 2e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A + VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kinase
HGK protein.
Length = 1239
Score = 65.7 bits (153), Expect = 2e-10
Identities = 55/212 (25%), Positives = 97/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V +E+ ++ ++L +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFI 90
Query: 385 ------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
H +L++V GS D++ + E A + R++L+ L +LH I
Sbjct: 91 KKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSD++S G+ + + P+
Sbjct: 202 CDENPDATYDYRSDLWSCGITAIEMAEGAPPL 233
>AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 65.7 bits (153), Expect = 2e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A + VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 8 protein.
Length = 1268
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 7 protein.
Length = 1297
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 6 protein.
Length = 1323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 5 protein.
Length = 1276
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 4 protein.
Length = 1352
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 3 protein.
Length = 1305
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 2 protein.
Length = 1331
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 1 protein.
Length = 1360
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 233
>AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein.
Length = 898
Score = 65.7 bits (153), Expect = 2e-10
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 3/199 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
VY A + VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 400 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 579
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 580 GANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKG-YDERS 756
G +L+ +A+ + P + W++PEV+ +G YD +
Sbjct: 156 TEPGQVKLADFGSAS-------------MASPANSFVGTPYWMAPEVILAMDEGQYDGKV 202
Query: 757 DIYSFGVLCLRTGQRGGPV 813
DI+S G+ C+ +R P+
Sbjct: 203 DIWSLGITCIELAERKPPL 221
>AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK
protein.
Length = 1165
Score = 65.7 bits (153), Expect = 2e-10
Identities = 55/212 (25%), Positives = 97/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V +E+ ++ ++L +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFI 90
Query: 385 ------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
H +L++V GS D++ + E A + R++L+ L +LH I
Sbjct: 91 KKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVI 150
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 201
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD RSD++S G+ + + P+
Sbjct: 202 CDENPDATYDYRSDLWSCGITAIEMAEGAPPL 233
>AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein.
Length = 1385
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Frame = +1
Query: 217 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 384
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 57 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 115
Query: 385 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 546
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 116 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 175
Query: 547 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL- 723
HR ++ +VL+ N +L +A + R +R + P W++PEV+
Sbjct: 176 HRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIA 226
Query: 724 -EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
++N YD +SD++S G+ + + P+
Sbjct: 227 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL 258
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 65.3 bits (152), Expect = 3e-10
Identities = 47/195 (24%), Positives = 95/195 (48%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIY 765
G A+L+ A + ++ + P ++PEV+++ GY+ +DI+
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTVIGTP---------FLMAPEVIQE--IGYNCVADIW 208
Query: 766 SFGVLCLRTGQRGGP 810
S G+ + + P
Sbjct: 209 SLGITAIEMAEGKPP 223
>AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein.
Length = 968
Score = 65.3 bits (152), Expect = 3e-10
Identities = 54/216 (25%), Positives = 100/216 (46%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D++ ++ I+ E DG VY A K A K +E + +++ ++L
Sbjct: 29 DLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATC 88
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H I+ L ++ H +L+++ G+ D + G++E +V R +L+AL
Sbjct: 89 D--HPYIVKLLGAYYHDGKLWIMIEFCPGGAV-DAIMLELDRGLTEPQIQVVCRQMLEAL 145
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
+LH + IHR ++A +VL+ G RL+ +A + L L D
Sbjct: 146 NFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA---------KNLKTLQKRDSFIGTP 196
Query: 700 MWLSPEVLE-QNLKG--YDERSDIYSFGVLCLRTGQ 798
W++PEV+ + +K YD ++DI+S G+ + Q
Sbjct: 197 YWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQ 232
>AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein.
Length = 1175
Score = 64.9 bits (151), Expect = 4e-10
Identities = 52/205 (25%), Positives = 93/205 (45%), Gaps = 9/205 (4%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV------H 387
VY + AIK V +E+ ++ ++L +K HH NI Y +F+ H
Sbjct: 2 VYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFIKKSPPGH 60
Query: 388 GRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRAS 567
+L++V GS D++ + E A + R++L+ L +LH IHR ++
Sbjct: 61 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ 120
Query: 568 HVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVL--EQNLKG 741
+VL+ N +L +A + R +R + P W++PEV+ ++N
Sbjct: 121 NVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIGTP--------YWMAPEVIACDENPDA 171
Query: 742 -YDERSDIYSFGVLCLRTGQRGGPV 813
YD RSD++S G+ + + P+
Sbjct: 172 TYDYRSDLWSCGITAIEMAEGAPPL 196
>BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase 10
protein.
Length = 968
Score = 64.5 bits (150), Expect = 5e-10
Identities = 55/216 (25%), Positives = 100/216 (46%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D++ ++ I+ E DG VY A K VA K +E + +++ ++L
Sbjct: 29 DLDPNEVWEIVGELGDGAFGKVYKAKNKETGALVAAKVIETKSEEELEDYIVEIEILATC 88
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H I+ L ++ H +L+++ G+ D + G++E V R +L+AL
Sbjct: 89 D--HPYIVKLLGAYYHDGKLWIMIEFCPGGAV-DAIMLELDRGLTEPQIQEVCRQMLEAL 145
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
+LH + IHR ++A +VL+ G RL+ +A + L L D
Sbjct: 146 NFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA---------KNLKTLQKRDSFIGTP 196
Query: 700 MWLSPEVLE-QNLKG--YDERSDIYSFGVLCLRTGQ 798
W++PEV+ + +K YD ++DI+S G+ + Q
Sbjct: 197 YWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQ 232
>BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein
protein.
Length = 1582
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/171 (25%), Positives = 77/171 (45%), Gaps = 9/171 (5%)
Frame = +1
Query: 328 LTRKELHHANILPYLASFV------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACA 489
L RK H NI+ + +F +L++V L + GS D++ + + E A
Sbjct: 96 LLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMTSNQSLKEGWIA 155
Query: 490 IVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLL 669
+ R++LQ L +LH IHR ++ +VL+ N +L +A + R+
Sbjct: 156 YICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGT 215
Query: 670 PPPDHDNANLMWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ E + YD RSD++S G+ + + P+
Sbjct: 216 P---------YWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEMAEGAPPL 257
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Frame = +1
Query: 319 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 498
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 499 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 663
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG-VLC 783
++ P W++PEVL L YDE++D+++FG VLC
Sbjct: 217 VVGSP-------YWMAPEVLRGEL--YDEKADVFAFGIVLC 248
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Frame = +1
Query: 319 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 498
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 499 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 663
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG-VLC 783
++ P W++PEVL L YDE++D+++FG VLC
Sbjct: 217 VVGSP-------YWMAPEVLRGEL--YDEKADVFAFGIVLC 248
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Frame = +1
Query: 319 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 498
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 499 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 663
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG-VLC 783
++ P W++PEVL L YDE++D+++FG VLC
Sbjct: 217 VVGSP-------YWMAPEVLRGEL--YDEKADVFAFGIVLC 248
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Frame = +1
Query: 319 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 498
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 499 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 663
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG-VLC 783
++ P W++PEVL L YDE++D+++FG VLC
Sbjct: 217 VVGSP-------YWMAPEVLRGEL--YDEKADVFAFGIVLC 248
>AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens
cDNA FLJ90247 fis, clone NT2RM2001902, highly similar to
Homo sapiens mRNA for PAK4 protein. ).
Length = 240
Score = 63.3 bits (147), Expect = 1e-09
Identities = 44/166 (26%), Positives = 81/166 (48%)
Frame = +1
Query: 289 RGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG 468
R +++ L+ +V+ ++ H N++ S++ G EL+VV + G+ DI+
Sbjct: 4 RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTH---TR 60
Query: 469 ISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQR 648
++E A V VLQAL LH Q IHR +++ +L+ +G +LS A + R
Sbjct: 61 MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPR 120
Query: 649 QRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVLCL 786
++ L P W++PE++ + Y DI+S G++ +
Sbjct: 121 RKSLVGTP---------YWMAPELISR--LPYGPEVDIWSLGIMVI 155
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 256 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 313
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 314 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 373
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 374 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 421
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 422 VWAFGVL 428
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 256 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 313
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 314 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 373
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 374 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 421
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 422 VWAFGVL 428
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 275 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 332
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 333 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 392
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 393 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 440
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 441 VWAFGVL 447
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 468 VWAFGVL 474
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 256 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 313
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 314 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 373
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 374 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 421
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 422 VWAFGVL 428
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 275 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 332
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 333 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 392
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 393 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 440
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 441 VWAFGVL 447
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 468 VWAFGVL 474
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 315 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 372
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 373 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 432
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 433 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 480
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 481 VWAFGVL 487
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 275 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 332
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 333 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 392
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 393 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 440
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 441 VWAFGVL 447
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 453 VWAFGVL 459
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 468 VWAFGVL 474
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 453 VWAFGVL 459
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 468 VWAFGVL 474
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 453 VWAFGVL 459
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 275 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 332
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 333 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 392
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 393 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 440
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 441 VWAFGVL 447
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 275 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 332
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 333 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 392
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 393 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 440
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 441 VWAFGVL 447
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 256 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 313
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 314 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 373
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 374 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 421
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 422 VWAFGVL 428
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 468 VWAFGVL 474
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 453 VWAFGVL 459
>AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-1
protein.
Length = 244
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Frame = +1
Query: 319 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 498
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 15 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEXLLSS--PEPLSWPVRLHLA 72
Query: 499 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 663
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 73 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 132
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFG-VLC 783
++ P W++PEVL L YDE++D+++FG VLC
Sbjct: 133 VVGSP-------YWMAPEVLRGEL--YDEKADVFAFGIVLC 164
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 75 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 132
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 133 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 192
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 193 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 240
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 241 VWAFGVL 247
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 405
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 293 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 350
Query: 406 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 585
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 351 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 410
Query: 586 NGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNAN--LMWLSPEVLEQNLKGYDERSD 759
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 411 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 458
Query: 760 IYSFGVL 780
+++FGVL
Sbjct: 459 VWAFGVL 465
>AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein.
Length = 302
Score = 61.3 bits (142), Expect = 4e-09
Identities = 52/191 (27%), Positives = 90/191 (47%), Gaps = 6/191 (3%)
Frame = +1
Query: 226 VYSALYKPNNTKVAIKR---YFVDRGKEKATLIQQ-DVLTRKELHHANILPYLASFVHGR 393
VY A + VA+K+ + + K +A I++ D+L K+L+H N++ Y ASF+
Sbjct: 48 VYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLL--KQLNHPNVIKYYASFIEDN 105
Query: 394 ELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIVLRDVLQALQYLHKQLYIHRSVRAS 567
EL +V L G ++ + + I E + AL+++H + +HR ++ +
Sbjct: 106 ELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPA 165
Query: 568 HVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYD 747
+V I A GV +L L + L P ++SPE + +N GY+
Sbjct: 166 NVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTP---------YYMSPERIHEN--GYN 214
Query: 748 ERSDIYSFGVL 780
+SDI+S G L
Sbjct: 215 FKSDIWSLGCL 225
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 39 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 98
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 99 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 155
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 156 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 206
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 207 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 242
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein.
Length = 1260
Score = 60.5 bits (140), Expect = 8e-09
Identities = 44/171 (25%), Positives = 79/171 (46%), Gaps = 9/171 (5%)
Frame = +1
Query: 328 LTRKELHHANILPYLASFV------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACA 489
+ +K HH NI Y +F+ H +L++V GS D++ + E A
Sbjct: 12 MLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIA 71
Query: 490 IVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLL 669
+ R++L+ L +LH IHR ++ +VL+ N +L +A + R +R +
Sbjct: 72 YISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSA-QLDRTVGRRNTFIG 130
Query: 670 PPPDHDNANLMWLSPEVL--EQNLKG-YDERSDIYSFGVLCLRTGQRGGPV 813
P W++PEV+ ++N YD RSD++S G+ + + P+
Sbjct: 131 TP--------YWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPL 173
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 60.5 bits (140), Expect = 8e-09
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = +1
Query: 166 DINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQDVLTRK 339
D+N II E DG VY A K + A K +E + +++ D+L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASC 86
Query: 340 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 519
+ H NI+ L +F + L+++ + G+ D + ++E +V + L AL
Sbjct: 87 D--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTESQIQVVCKQTLDAL 143
Query: 520 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANL 699
YLH IHR ++A ++L +G +L+ +A QR+ P
Sbjct: 144 NYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP--------- 194
Query: 700 MWLSPEVL---EQNLKGYDERSDIYSFGVLCLRTGQ 798
W++PEV+ + YD ++D++S G+ + +
Sbjct: 195 YWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 protein.
Length = 740
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 599
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDD 624
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 115 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 169
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 170 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 226
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 227 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 257
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 variant protein.
Length = 806
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 500 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 555
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 556 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 612
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 613 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 665
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 666 DIWSLGVLLYTMLTGYTPFANGPDD 690
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 182 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 236
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 237 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 293
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 294 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 324
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 60.1 bits (139), Expect = 1e-08
Identities = 59/205 (28%), Positives = 98/205 (47%), Gaps = 1/205 (0%)
Frame = +1
Query: 220 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 399
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 420 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 475
Query: 400 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 576
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 476 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 532
Query: 577 IGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERS 756
+ +R + Q + + LL P + AN +++PEVL++ +GYD
Sbjct: 533 Y-VDESGNPESIRICDFGFAK-QLRAENGLLMTPCY-TAN--FVAPEVLKR--QGYDAAC 585
Query: 757 DIYSFGVLCLRTGQRGGPVRRSPHD 831
DI+S GVL P P D
Sbjct: 586 DIWSLGVLLYTMLTGYTPFANGPDD 610
Score = 36.3 bits (80), Expect = 0.14
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +1
Query: 307 TLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI-SELA 483
T +++D+L E++H I+ +F +LY++ + G D+ R E + +E
Sbjct: 101 TKMERDILV--EVNHPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLSKEVMFTEED 155
Query: 484 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 663
L ++ AL +LH I+R ++ ++L+ G +L+ + + ++K +
Sbjct: 156 VKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESI---DHEKKAY 212
Query: 664 LLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
+ +++PEV+ N +G+ + +D +SFGVL
Sbjct: 213 SFC------GTVEYMAPEVV--NRRGHTQSADWWSFGVL 243
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 59.7 bits (138), Expect = 1e-08
Identities = 57/180 (31%), Positives = 91/180 (50%), Gaps = 6/180 (3%)
Frame = +1
Query: 259 KVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRE-LYVVSPLMSFGSC 435
KVA+K D +A L + V+T +L H+N++ L V + LY+V+ M+ GS
Sbjct: 218 KVAVKCIKND-ATAQAFLAEASVMT--QLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSL 274
Query: 436 RDILDRYFPEGISELACAIVLR---DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 606
D L G S L +L+ DV +A++YL ++HR + A +VL+ + VA++S
Sbjct: 275 VDYLRS---RGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVS 331
Query: 607 --GLRTAASMMVRGQRQRKLHLLPPPDHDNANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
GL AS G+ LP + W +PE L + K + +SD++SFG+L
Sbjct: 332 DFGLTKEASTQDTGK-------LP--------VKWTAPEALRE--KKFSTKSDVWSFGIL 374
>CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 204
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 205 ----YYMSPERIHEN--GYNFKSDIWSLGCL 229
>CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 204
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 205 ----YYMSPERIHEN--GYNFKSDIWSLGCL 229
>BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 132 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 190
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 191 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 245
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 246 ----YYMSPERIHEN--GYNFKSDIWSLGCL 270
>AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 211
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 212 ----YYMSPERIHEN--GYNFKSDIWSLGCL 236
>AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 132 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 190
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 191 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 245
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 246 ----YYMSPERIHEN--GYNFKSDIWSLGCL 270
>AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6
protein.
Length = 338
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 123 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 181
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 182 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 236
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 237 ----YYMSPERIHEN--GYNFKSDIWSLGCL 261
>AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-1512
protein.
Length = 306
Score = 58.8 bits (136), Expect = 2e-08
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = +1
Query: 337 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 507
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 508 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLPPPDHD 687
A++++H + +HR ++ ++V I A GV +L L + L+ P
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDL--GLGRFFSSETTAAHSLVGTP--- 204
Query: 688 NANLMWLSPEVLEQNLKGYDERSDIYSFGVL 780
++SPE + +N GY+ +SDI+S G L
Sbjct: 205 ----YYMSPERIHEN--GYNFKSDIWSLGCL 229
>U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein.
Length = 633
Score = 58.4 bits (135), Expect = 3e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 9/184 (4%)
Frame = +1
Query: 259 KVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCR 438
+V + + + +E ++V + L H N+L ++ + L ++ + G+ R
Sbjct: 349 EVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLR 408
Query: 439 DIL---DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSG 609
I+ D +P ++ A +D+ + YLH IHR + + + L+ N ++
Sbjct: 409 GIIKSMDSQYPWS-QRVSFA---KDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVAD 464
Query: 610 LRTAASMMVRGQRQRKLHLLPPPDHDN-----ANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A M+ + L L PD N W++PE++ N + YDE+ D++SFG
Sbjct: 465 FGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI--NGRSYDEKVDVFSFG 522
Query: 775 -VLC 783
VLC
Sbjct: 523 IVLC 526
>U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein.
Length = 647
Score = 58.4 bits (135), Expect = 3e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 9/184 (4%)
Frame = +1
Query: 259 KVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCR 438
+V + + + +E ++V + L H N+L ++ + L ++ + G+ R
Sbjct: 363 EVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLR 422
Query: 439 DIL---DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSG 609
I+ D +P ++ A +D+ + YLH IHR + + + L+ N ++
Sbjct: 423 GIIKSMDSQYPWS-QRVSFA---KDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVAD 478
Query: 610 LRTAASMMVRGQRQRKLHLLPPPDHDN-----ANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A M+ + L L PD N W++PE++ N + YDE+ D++SFG
Sbjct: 479 FGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI--NGRSYDEKVDVFSFG 536
Query: 775 -VLC 783
VLC
Sbjct: 537 IVLC 540
>U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced
LIM-kinase1 protein.
Length = 633
Score = 58.4 bits (135), Expect = 3e-08
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 9/184 (4%)
Frame = +1
Query: 259 KVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCR 438
+V + + + +E ++V + L H N+L ++ + L ++ + G+ R
Sbjct: 349 EVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLR 408
Query: 439 DIL---DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSG 609
I+ D +P ++ A +D+ + YLH IHR + + + L+ N ++
Sbjct: 409 GIIKSMDSQYPWS-QRVSFA---KDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVAD 464
Query: 610 LRTAASMMVRGQRQRKLHLLPPPDHDN-----ANLMWLSPEVLEQNLKGYDERSDIYSFG 774
A M+ + L L PD N W++PE++ N + YDE+ D++SFG
Sbjct: 465 FGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI--NGRSYDEKVDVFSFG 522
Query: 775 -VLC 783
VLC
Sbjct: 523 IVLC 526
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,398,007
Number of Sequences: 237096
Number of extensions: 2897865
Number of successful extensions: 12249
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10769
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11600
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10872716010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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