Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_L24
(807 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D50929-1|BAA09488.2| 1388|Homo sapiens KIAA0139 protein. 298 1e-80
U78311-1|AAB80695.1| 1382|Homo sapiens translation initiation fa... 298 2e-80
U58046-1|AAB41584.1| 1382|Homo sapiens p167 protein. 298 2e-80
BC114429-1|AAI14430.1| 1382|Homo sapiens eukaryotic translation ... 298 2e-80
BC107776-1|AAI07777.1| 640|Homo sapiens EIF3A protein protein. 298 2e-80
BC064926-1|AAH64926.1| 636|Homo sapiens EIF3A protein protein. 298 2e-80
BC054342-1|AAH54342.1| 812|Homo sapiens EIF3A protein protein. 298 2e-80
BC033769-1|AAH33769.1| 634|Homo sapiens EIF3A protein protein. 298 2e-80
AL355598-2|CAI14127.1| 1382|Homo sapiens eukaryotic translation ... 298 2e-80
AK131255-1|BAD18434.1| 957|Homo sapiens protein ( Homo sapiens ... 206 7e-53
AY282495-1|AAP22284.1| 2764|Homo sapiens bromodomain PHD finger ... 33 0.92
AB032251-1|BAA89208.1| 2781|Homo sapiens bromodomain PHD finger ... 33 1.2
AF065482-1|AAC17181.1| 519|Homo sapiens sorting nexin 2 protein. 30 8.6
>D50929-1|BAA09488.2| 1388|Homo sapiens KIAA0139 protein.
Length = 1388
Score = 298 bits (732), Expect = 1e-80
Identities = 140/224 (62%), Positives = 176/224 (78%)
Frame = +2
Query: 134 KMARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLEL 313
+M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLEL
Sbjct: 6 EMPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLEL 63
Query: 314 CVDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDD 493
CVDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +D
Sbjct: 64 CVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIED 123
Query: 494 LDNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDI 673
LDN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDI
Sbjct: 124 LDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDI 183
Query: 674 ARMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
A+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 184 AQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 227
>U78311-1|AAB80695.1| 1382|Homo sapiens translation initiation
factor 3 large subunit protein.
Length = 1382
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>U58046-1|AAB41584.1| 1382|Homo sapiens p167 protein.
Length = 1382
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>BC114429-1|AAI14430.1| 1382|Homo sapiens eukaryotic translation
initiation factor 3, subunit A protein.
Length = 1382
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>BC107776-1|AAI07777.1| 640|Homo sapiens EIF3A protein protein.
Length = 640
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>BC064926-1|AAH64926.1| 636|Homo sapiens EIF3A protein protein.
Length = 636
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>BC054342-1|AAH54342.1| 812|Homo sapiens EIF3A protein protein.
Length = 812
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>BC033769-1|AAH33769.1| 634|Homo sapiens EIF3A protein protein.
Length = 634
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>AL355598-2|CAI14127.1| 1382|Homo sapiens eukaryotic translation
initiation factor 3, subunit 10 theta, 150/170kDa
protein.
Length = 1382
Score = 298 bits (731), Expect = 2e-80
Identities = 140/223 (62%), Positives = 175/223 (78%)
Frame = +2
Query: 137 MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELC 316
M Y QRPENALKRANEF+++ K ALD L +V ++KK W + + EPIM KYLELC
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHR-TW-QKIHEPIMLKYLELC 58
Query: 317 VDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDL 496
VDLRKSH+AKEGL+QY+N+ Q VN+ SLE V+R YL+MAEE+TE A+ S Q V+D +DL
Sbjct: 59 VDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDL 118
Query: 497 DNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIA 676
DN+ TPES+LLSAVSGED QDR+DR +LTPWVKFLWESY QCL+LLR N+ VE LYHDIA
Sbjct: 119 DNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIA 178
Query: 677 RMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSIS 805
+ AF+FCL+Y+RK EFRKLCD LR HL I + Q+ ++++
Sbjct: 179 QQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLN 221
>AK131255-1|BAD18434.1| 957|Homo sapiens protein ( Homo sapiens
cDNA FLJ16186 fis, clone BRTHA2007060, moderately
similar to EUKARYOTIC TRANSLATION INITIATION FACTOR 3
SUBUNIT 10. ).
Length = 957
Score = 206 bits (503), Expect = 7e-53
Identities = 101/208 (48%), Positives = 143/208 (68%), Gaps = 2/208 (0%)
Frame = +2
Query: 155 RPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELCVDLRKS 334
+PENALKRA E +++ + AL TL ++ +K++ W ++ LE IMFKY+ELCVD+RK
Sbjct: 6 KPENALKRAEELINVGQKQDALQTLHDLITSKRYRA-WQKT-LERIMFKYVELCVDMRKG 63
Query: 335 HVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETAR--ALSTQAVIDTDDLDNLA 508
AK+GL QYR + Q VNV SLE+VI+ +++++ E+ E AR A + + +D DDL+
Sbjct: 64 RFAKDGLIQYRIICQQVNVSSLEEVIKHFMQLSTEKAEQARSQAQALEEALDVDDLEADK 123
Query: 509 TPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIARMAF 688
PE ++LS VSGE +DRSDR +TPW KFLWE+Y LE+LR N+ +E LY A AF
Sbjct: 124 RPEDLMLSYVSGEKGKDRSDRETVTPWFKFLWETYRTVLEILRNNSKLEALYAMTAHRAF 183
Query: 689 QFCLKYSRKTEFRKLCDKLRKHLEDICK 772
QFC +Y R TE R+LC+ +R HL ++ K
Sbjct: 184 QFCKQYKRTTELRRLCEIIRNHLANLNK 211
>AY282495-1|AAP22284.1| 2764|Homo sapiens bromodomain PHD finger
transcription factor protein.
Length = 2764
Score = 33.5 bits (73), Expect = 0.92
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +2
Query: 65 SVFSPKPT*NRRNCV-NEVESDIKKMARYGQRPENALKRANE-FMDLDKPARALDTLQEV 238
S+ SP+ ++N + N++E + +A GQ P + + N+ F+D K A A D +
Sbjct: 1158 SIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLI 1217
Query: 239 FRNKK 253
+NKK
Sbjct: 1218 CKNKK 1222
>AB032251-1|BAA89208.1| 2781|Homo sapiens bromodomain PHD finger
transcription factor protein.
Length = 2781
Score = 33.1 bits (72), Expect = 1.2
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +2
Query: 65 SVFSPKPT*NRRNCV-NEVESDIKKMARYGQRPENALKRANE-FMDLDKPARALDTLQEV 238
S+ SP+ ++N + N++E + +A GQ P + + N+ F+D K A A D +
Sbjct: 1032 SIRSPETKCPKQNSIENDIEEKVSDLASRGQEPTKSKTKGNDFFIDDSKLASADDIGTLI 1091
Query: 239 FRNKK 253
+NKK
Sbjct: 1092 CKNKK 1096
>AF065482-1|AAC17181.1| 519|Homo sapiens sorting nexin 2 protein.
Length = 519
Score = 30.3 bits (65), Expect = 8.6
Identities = 25/81 (30%), Positives = 40/81 (49%)
Frame = +2
Query: 263 NWSESVLEPIMFKYLELCVDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEER 442
N S++ E ++ L LRK HV+ E LF +R S N + + L +E+
Sbjct: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALFCHRKEL-SANTAAFAK-SAAMLGNSEDH 357
Query: 443 TETARALSTQAVIDTDDLDNL 505
T +RALS A ++ + +D L
Sbjct: 358 TALSRALSQLAEVE-EKIDQL 377
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 135,912,854
Number of Sequences: 237096
Number of extensions: 3362954
Number of successful extensions: 6648
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6302
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6637
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9980595722
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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