Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_L12
(933 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 330 2e-89
UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|R... 279 1e-73
UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium t... 270 3e-71
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 268 1e-70
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 262 7e-69
UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Re... 247 3e-64
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 241 2e-62
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 236 5e-61
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ... 235 9e-61
UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=... 232 1e-59
UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Re... 220 5e-56
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas... 217 3e-55
UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium t... 216 8e-55
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 214 2e-54
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 212 9e-54
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 210 4e-53
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad... 210 5e-53
UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Re... 206 5e-52
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 205 1e-51
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 202 1e-50
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 183 7e-45
UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella ve... 181 3e-44
UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmi... 175 1e-42
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo... 150 4e-35
UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella chej... 117 5e-25
UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;... 116 7e-25
UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1; ... 110 6e-23
UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate deh... 101 3e-20
UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;... 98 3e-19
UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21; Amniota|... 88 3e-16
UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep: Zgc:1... 85 2e-15
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 73 8e-12
UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD (so... 72 2e-11
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 66 2e-09
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 65 2e-09
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 60 6e-08
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 59 1e-07
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 59 1e-07
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 56 1e-06
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 56 1e-06
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 55 2e-06
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 54 4e-06
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 53 9e-06
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 53 1e-05
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 52 2e-05
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 52 3e-05
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 49 2e-04
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 49 2e-04
UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to tetratrico... 47 6e-04
UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 47 8e-04
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 46 0.002
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 45 0.003
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 45 0.003
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 44 0.004
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 44 0.004
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 44 0.006
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 44 0.007
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 44 0.007
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 44 0.007
UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein NCU048... 43 0.013
UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4; Euteleost... 42 0.017
UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1; ... 42 0.017
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 42 0.030
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 41 0.052
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 40 0.12
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.16
UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium salinarum|... 38 0.48
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 38 0.48
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 36 1.1
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 36 1.1
UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep... 36 1.5
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 36 1.5
UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep... 36 1.5
UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genom... 36 1.9
UniRef50_O97299 Cluster: Putative uncharacterized protein MAL3P7... 36 1.9
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 36 1.9
UniRef50_Q9BYR4 Cluster: Keratin-associated protein 4-3; n=53; M... 36 1.9
UniRef50_Q827S2 Cluster: Putative aminodeoxychorismate lyase; n=... 35 2.6
UniRef50_Q2RQ78 Cluster: Putative uncharacterized protein; n=1; ... 35 2.6
UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7; ... 35 2.6
UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P... 35 2.6
UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidas... 35 2.6
UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein fa... 35 3.4
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 35 3.4
UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococ... 34 4.5
UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Ce... 34 4.5
UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin as... 34 5.9
UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep... 34 5.9
UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1; ... 34 5.9
UniRef50_Q1JTH9 Cluster: Hyothetical protein; n=4; root|Rep: Hyo... 34 5.9
UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34; Prote... 34 5.9
UniRef50_UPI00006CFE65 Cluster: hypothetical protein TTHERM_0069... 33 7.9
UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep: ... 33 7.9
UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3; Sordariom... 33 7.9
UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila mela... 33 7.9
UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47; Craniat... 33 7.9
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase,
cytoplasmic - Homo sapiens (Human)
Length = 334
Score = 330 bits (812), Expect = 2e-89
Identities = 160/256 (62%), Positives = 193/256 (75%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 339
M+EPIRV+VTGAAGQIAYSLLY I +G+VFG QP+ L LLDI PMMGVL+GV+MEL DC
Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC 60
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
ALPLL V+ T + AFKD+ A LVG+MPR+EGMERKDLL ANV+IFK QG ALDK A
Sbjct: 61 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA 120
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
+K VKV+VVGNPANTN L SK APSIPKENF+ +TRLD NRA++Q+A K+GV DVK
Sbjct: 121 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN 180
Query: 700 VIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXX 879
VIIWGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RGAAVI
Sbjct: 181 VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL 240
Query: 880 XXXXXXXXXXXXHMKN 927
H+++
Sbjct: 241 SSAMSAAKAICDHVRD 256
>UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|Rep:
Malate dehydrogenase - Caenorhabditis elegans
Length = 336
Score = 279 bits (683), Expect = 1e-73
Identities = 136/236 (57%), Positives = 170/236 (72%), Gaps = 1/236 (0%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 339
M+ P+RV+VTGAAGQI YS++ +IA G VFG +QPV L LLD+ +LEGVV EL DC
Sbjct: 1 MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDC 60
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
ALP L V+ + + AF + AFLVGAMPR+EGMERKDLLAANV+IFK QG+AL + A
Sbjct: 61 ALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKDLLAANVKIFKSQGKALAEYA 120
Query: 520 RKDVKVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 696
+ KV+VVGNPANTNA I +KYA IP +NF+AMTRLD NRA +QLA K G + +VK
Sbjct: 121 KPTTKVIVVGNPANTNAFIAAKYAAGKIPAKNFSAMTRLDHNRALAQLALKTGTTIGNVK 180
Query: 697 RVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
VIIWGNHS TQFPD ++A G + + D+A+L+G F+ TVQKRG +I
Sbjct: 181 NVIIWGNHSGTQFPDVTHATVNKNGTETDAYAAVGDNAFLQGPFIATVQKRGGVII 236
>UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 356
Score = 270 bits (663), Expect = 3e-71
Identities = 132/251 (52%), Positives = 167/251 (66%)
Frame = +1
Query: 169 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 348
P+RV VTGAAG I Y+L++ I G + GP Q + L LL++ LEG +MEL DCA P
Sbjct: 26 PVRVTVTGAAGNIGYALVHMIGQGRLLGPNQQIILTLLELPMAKDQLEGTMMELRDCAFP 85
Query: 349 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 528
+L + T ++ F A LVGA PR GMERKDLLAAN RIFKEQG+AL+K A K+
Sbjct: 86 ILKEIRGTTQYDQGFMGCEIAILVGAKPRGPGMERKDLLAANARIFKEQGEALEKYASKN 145
Query: 529 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 708
VKVLVVGNPANTNALI +++APSIPK NFTA+TRLDQNRAQS +A ++ V+DV+ +II
Sbjct: 146 VKVLVVGNPANTNALITAQFAPSIPKSNFTALTRLDQNRAQSIIAQRVSANVEDVRNIII 205
Query: 709 WGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXXX 888
WGNHS+TQF D S A G ++V ++ DDA+L+ AFV V KRG A+I
Sbjct: 206 WGNHSTTQFADVSQATVQQNGISQTVRGLVADDAWLQKAFVEQVAKRGGAIIEKRKASSA 265
Query: 889 XXXXXXXXXHM 921
H+
Sbjct: 266 ASAASAVCDHI 276
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 268 bits (658), Expect = 1e-70
Identities = 131/254 (51%), Positives = 169/254 (66%)
Frame = +1
Query: 166 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 345
+P++V+VTGAAGQI Y+++ IA G + G QPV LHLLD+ L GV MEL D AL
Sbjct: 25 KPVKVLVTGAAGQIGYAIVAMIAKGLMLGADQPVVLHLLDLPVAANALNGVRMELIDAAL 84
Query: 346 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
PLL GV+ T++ EAFK V A L+G PR++GMERKDL++ NV I+K Q AL + A
Sbjct: 85 PLLRGVVATSDEAEAFKGVNVAILIGGWPRRDGMERKDLISKNVTIYKSQASALQQHAAP 144
Query: 526 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
+ KVLVV NPANTNAL+ ++AP+IP +N T +TRLD NRA Q+A K+ V V DVK I
Sbjct: 145 NCKVLVVANPANTNALVLKEFAPAIPAKNITCLTRLDHNRALGQVAEKLNVHVGDVKNAI 204
Query: 706 IWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXX 885
IWGNHSSTQFPDAS+A ++ V E+I D+ +L+ FVT VQ+RGAAVI
Sbjct: 205 IWGNHSSTQFPDASHATVSTDRGERPVRELIADEIWLREEFVTDVQQRGAAVIKARKQSS 264
Query: 886 XXXXXXXXXXHMKN 927
HM++
Sbjct: 265 SLSAASAACDHMRD 278
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 262 bits (643), Expect = 7e-69
Identities = 138/256 (53%), Positives = 168/256 (65%), Gaps = 2/256 (0%)
Frame = +1
Query: 166 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAP--MMGVLEGVVMELADC 339
+P+RV VTGAAGQI Y+LL++IASG + G QPV L LL+I L+GV+MEL DC
Sbjct: 4 KPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDC 63
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
A PLLAG+ ++P AFKD A LVGA PR GMER DLLAAN +IF QG+AL+ A
Sbjct: 64 AFPLLAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVA 123
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
++VKVLVVGNPANTNA I K AP +P +NFTAM RLD NRA SQLAAK G V D+K+
Sbjct: 124 SRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQLAAKGGFKVGDIKK 183
Query: 700 VIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXX 879
+ +WGNHS T + D A V G KSV + IND A+ K F+ TV KRGAA+I
Sbjct: 184 LTVWGNHSPTMYAD--YRFATVDG--KSVKDAINDPAWYKDVFLPTVGKRGAAIIAARGL 239
Query: 880 XXXXXXXXXXXXHMKN 927
HM++
Sbjct: 240 SSAASAANAAIDHMRD 255
>UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Rep:
Malate dehydrogenase - Frankia sp. (strain CcI3)
Length = 329
Score = 247 bits (605), Expect = 3e-64
Identities = 125/251 (49%), Positives = 163/251 (64%)
Frame = +1
Query: 169 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 348
P+ V VTGAAGQI Y+LL++IASG + G PV L LL+I + EG +EL D A P
Sbjct: 5 PVNVTVTGAAGQIGYALLFRIASGQLLGADTPVKLRLLEIPQAVRAAEGTALELEDSAFP 64
Query: 349 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 528
LLAGV + + AF+ A LVGA PR +GMER DLL+AN IFK QG+A++ A +D
Sbjct: 65 LLAGVDVFDDAKRAFEGTNVALLVGARPRTKGMERGDLLSANGGIFKPQGEAINSGAAED 124
Query: 529 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 708
++VLVVGNPANTNALI +AP +P E FTAMTRLD NRA +QLA K+GVP ++K++ I
Sbjct: 125 IRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLDHNRAIAQLAKKLGVPSAEIKKITI 184
Query: 709 WGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXXX 888
WGNHS+TQ+PD +A VGG +S +E + D A++ F+ V KRGA +I
Sbjct: 185 WGNHSATQYPDIFHAE--VGG--RSGAEAVGDQAWIADEFIPRVAKRGAEIIEVRGASSA 240
Query: 889 XXXXXXXXXHM 921
H+
Sbjct: 241 ASAASAAIDHI 251
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 241 bits (589), Expect = 2e-62
Identities = 135/266 (50%), Positives = 164/266 (61%), Gaps = 10/266 (3%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMG--VLEGVVMELA 333
M P+RV VTGAAGQI Y+LL++IASGA+ G QPV L LL+I L+GV+MEL
Sbjct: 1 MKAPVRVAVTGAAGQIGYALLFRIASGAMLGADQPVILQLLEIPDEKAQKALKGVMMELE 60
Query: 334 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 513
DCA PLL ++ T +P AFKD A LVGA PR GMERKDLL AN +IF QG+A+ K
Sbjct: 61 DCAFPLLHSMIATGDPAVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGK 120
Query: 514 AARKDVKVLVVGNPANTNALICSKYAPS---IPKENFTAMTRLDQNRAQSQLAAKIGVPV 684
A +VKVLVVGNPANTNA I K A + +NFTAM RLD NRA SQLA K G PV
Sbjct: 121 YANPNVKVLVVGNPANTNAYIAMKSAMKHGRVKAKNFTAMLRLDHNRALSQLATKTGKPV 180
Query: 685 KDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEII-----NDDAYLKGAFVTTVQKR 849
K+V +WGNHS T +PD A A GA+ V E++ DA+ K F+ TV KR
Sbjct: 181 ASFKKVAVWGNHSPTMYPDVRFATA--DGAK--VPELLKLGTAEGDAWNKDTFIPTVGKR 236
Query: 850 GAAVIXXXXXXXXXXXXXXXXXHMKN 927
GAA+I H+++
Sbjct: 237 GAAIIEARGLSSAASAASAAVDHIRD 262
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 236 bits (578), Expect = 5e-61
Identities = 123/255 (48%), Positives = 159/255 (62%)
Frame = +1
Query: 157 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
K + I V VTGAAGQI Y+ L + +G FG ++ + L LLD+ +L+GV +EL D
Sbjct: 41 KENDEINVCVTGAAGQIGYAFLPLLLTGQCFGDKK-INLRLLDVPQAESILQGVELELQD 99
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
A PLL + +N F+DV A +G PRK GMERKDLL N IFK+QGQALD
Sbjct: 100 GAYPLLKSIKTGSNESILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTV 159
Query: 517 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 696
A+K K LVV NPANTN LI ++ A SIPK+NF+A+TRLD NRA SQ+A K G + DVK
Sbjct: 160 AKKTCKSLVVANPANTNCLILAETAKSIPKQNFSALTRLDHNRAISQIALKAGCSITDVK 219
Query: 697 RVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXX 876
VIIWGNHS+TQ+PD ++ ++G K + + IND+AYL AF+ VQKRG V+
Sbjct: 220 NVIIWGNHSTTQYPDVNHG-TVLG---KRIRQFINDEAYLNNAFIERVQKRGGEVLAARK 275
Query: 877 XXXXXXXXXXXXXHM 921
H+
Sbjct: 276 NSSVMSAANAVKDHL 290
>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
putative - Leishmania major
Length = 324
Score = 235 bits (576), Expect = 9e-61
Identities = 132/232 (56%), Positives = 152/232 (65%), Gaps = 1/232 (0%)
Frame = +1
Query: 172 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 351
++V VTGAAGQI Y+L+ IA GA+ GP PV L LLDI P + L GV EL DCA PL
Sbjct: 4 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 63
Query: 352 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDV 531
L V+ TA+P AF VA A + GA PRK GMERKDLL N RIFKEQG+A+ A D
Sbjct: 64 LDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASDC 123
Query: 532 KVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 708
+V+VVGNPANTNALI K A + + TAMTRLD NRA S LA K GVPV V+ VII
Sbjct: 124 RVVVVGNPANTNALILLKSAQGKLNPRHVTAMTRLDHNRALSLLARKAGVPVSQVRNVII 183
Query: 709 WGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
WGNHSSTQ PD +AV +G E I DDA L FV V+ RGA +I
Sbjct: 184 WGNHSSTQVPDTDSAV--IG--TTPAREAIKDDA-LDDDFVQVVRGRGAEII 230
>UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=2;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 1 - Entamoeba histolytica
Length = 355
Score = 232 bits (567), Expect = 1e-59
Identities = 122/255 (47%), Positives = 162/255 (63%)
Frame = +1
Query: 163 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCA 342
++P+ V+VTGAAGQI Y+LL+ IA G +FGP Q V+LHL DI M+ +EGV MELADC
Sbjct: 22 SKPLHVLVTGAAGQIGYNLLFLIAHGLMFGPNQTVYLHLYDI--MVEAMEGVKMELADCC 79
Query: 343 LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAAR 522
PL+ GV+ + E AFKDV A LV MPRK GMERK+L+ N RI KEQ AL A
Sbjct: 80 FPLVKGVVASNKTEVAFKDVECAILVAGMPRKVGMERKELIGINTRIMKEQALALKNFAN 139
Query: 523 KDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 702
V+VLVV NPANTNAL+ + A I + T +TRLDQNRA +Q+A+K+ V+DV
Sbjct: 140 PHVRVLVVANPANTNALVVANNA-GIDVKQITCLTRLDQNRAIAQIASKLNCKVEDVSDA 198
Query: 703 IIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXX 882
+WGNHS Q PD S+AV K V++++ ++++L+ +F TVQ+RGA VI
Sbjct: 199 FVWGNHSEKQCPDISHAVVQTPNGPKRVADLV-EESWLE-SFNKTVQERGAKVIEMRKAS 256
Query: 883 XXXXXXXXXXXHMKN 927
H ++
Sbjct: 257 SAASAAKAIVDHFRD 271
>UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Rep:
Malate dehydrogenase - Mastigamoeba balamuthi
(Phreatamoeba balamuthi)
Length = 382
Score = 220 bits (537), Expect = 5e-56
Identities = 117/239 (48%), Positives = 149/239 (62%), Gaps = 5/239 (2%)
Frame = +1
Query: 163 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIA--PMMGVLEGVVMELAD 336
A P+ V +TG AGQIAYSL + IA G + G QPV L LLD+ E VVMEL D
Sbjct: 44 AAPLHVTLTGGAGQIAYSLAFLIARGQMLGLYQPVVLRLLDLPRPEKQRAQEAVVMELKD 103
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
CA LL V+ TA+P EAF LVG+ PR G R+DLLA N IFK QG+A+
Sbjct: 104 CAFGLLRDVVATADPREAFAGAHVVVLVGSSPRAAGQLRRDLLAQNAAIFKAQGKAVSDY 163
Query: 517 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 696
A DV+VLVV NPANTN L+ S+ AP+IP+ + + MTRLD NR+++Q+A ++GV ++V
Sbjct: 164 ADPDVRVLVVANPANTNCLVFSRCAPNIPRTHVSCMTRLDHNRSKAQIAERVGVETRNVH 223
Query: 697 RVIIWGNHSSTQFPDASNAVA---IVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
I+WGNHS TQ+PD A GA +INDD ++ FV TVQ+RG VI
Sbjct: 224 NAIVWGNHSGTQYPDLRFARVDDFPTKGASTPARALINDDEWVFKTFVPTVQQRGYKVI 282
>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
precursor; n=62; cellular organisms|Rep: Malate
dehydrogenase [NADP], chloroplast precursor - Zea mays
(Maize)
Length = 432
Score = 217 bits (530), Expect = 3e-55
Identities = 120/231 (51%), Positives = 148/231 (64%)
Frame = +1
Query: 172 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 351
+ V V+GAAG I+ LL+++ASG VFG QP+ L LL LEGV MEL D PL
Sbjct: 90 VNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPL 149
Query: 352 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDV 531
L V +P F+DV A L+GA PR GMER LL N +IF +QG+AL+ A ++
Sbjct: 150 LREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRND 209
Query: 532 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 711
+VLVVGNP NTNALIC K AP+IP +NF A+TRLD+NRA+ QLA K GV V V IW
Sbjct: 210 EVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIW 269
Query: 712 GNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
GNHS+TQ PD NA I G + V E+I D +L+ F TVQKRG +I
Sbjct: 270 GNHSTTQVPDFLNA-KIDG---RPVKEVIKDTKWLEEEFTLTVQKRGGVLI 316
>UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 360
Score = 216 bits (527), Expect = 8e-55
Identities = 109/240 (45%), Positives = 145/240 (60%)
Frame = +1
Query: 202 QIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANP 381
++ YSL++++ASG + GP QPV LHL+D+ M L GVVME+ DCA PL+ G++ T N
Sbjct: 51 KLGYSLIFRVASGEMLGPNQPVILHLIDLPFAMAALNGVVMEIQDCAFPLVQGIVATDNQ 110
Query: 382 EEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPAN 561
FKDV A +VGA PR GMER DLL N +IF E G+ ++ A +D+KV+VVGNP N
Sbjct: 111 SVGFKDVNYALMVGAKPRGPGMERGDLLKDNGKIFTETGKYINDHASRDIKVVVVGNPCN 170
Query: 562 TNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPD 741
TN LI + IPKENFTAMTRLD NRAQ QLA K+GV D++++ I+GNHS T P
Sbjct: 171 TNCLILANQIKDIPKENFTAMTRLDHNRAQHQLADKLGVHTSDIRKIAIFGNHSPTMVPY 230
Query: 742 ASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXXHM 921
A K+ + D ++ F+ TVQ+RGA +I H+
Sbjct: 231 IDQMTA------KNHKATV-DQQWVTQTFIPTVQQRGAEIIKARKLSSAASAGNAAMNHI 283
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 214 bits (523), Expect = 2e-54
Identities = 115/233 (49%), Positives = 150/233 (64%)
Frame = +1
Query: 166 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 345
E +RV VTG GQIAY+ L+ +A G VFG + V L + D+ L GV MEL D A
Sbjct: 5 EVVRVAVTGGKGQIAYNFLFALAHGDVFGVDRGVDLRIYDVPGTERALSGVRMELDDGAY 64
Query: 346 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
PLL + T + +AF + AAFL+GA+PR GMER DLL N +IF QG AL+ AA++
Sbjct: 65 PLLHRLRVTTSLNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR 124
Query: 526 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
D K+ VVGNP NTN I K+AP + ++NF AM RLDQNR S LA + VP+++V RV+
Sbjct: 125 DAKIFVVGNPVNTNCWIAMKHAPRLHRKNFHAMLRLDQNRMHSMLAHRAEVPLEEVSRVV 184
Query: 706 IWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
IWGNHS+ Q PD + A I G K +E+I D +L+ V +VQ RG+AVI
Sbjct: 185 IWGNHSAKQVPDFTQA-RISG---KPAAEVIGDRDWLENILVHSVQNRGSAVI 233
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 212 bits (518), Expect = 9e-54
Identities = 117/218 (53%), Positives = 145/218 (66%), Gaps = 1/218 (0%)
Frame = +1
Query: 214 SLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAF 393
+L ++IA G + G ++ VFLH L+I M LEG VMEL DCA P +AG++ T EEAF
Sbjct: 1 ALTFRIAKGDLCGDRK-VFLHHLEIPFGMKALEGCVMELQDCAFPNVAGIVWTDKIEEAF 59
Query: 394 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 573
KDV AFLVG+ PRK+GM+R DLLA N IF QG+AL A+KDVKVLVVGNPANTN L
Sbjct: 60 KDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDVKVLVVGNPANTNCL 119
Query: 574 ICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNA 753
I AP++ K+N+ AMTRLD NR LAAK GV + V VI+WGNHS+TQ PDA +A
Sbjct: 120 IAQASAPNLSKKNWCAMTRLDHNRMVGALAAKFGVTPEKVHNVIVWGNHSNTQVPDAYHA 179
Query: 754 -VAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
V + G K ++ D YL+ F + RG AVI
Sbjct: 180 TVDLPEGTVKVADKL--DAEYLEKEFAPMIATRGGAVI 215
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 210 bits (513), Expect = 4e-53
Identities = 112/259 (43%), Positives = 156/259 (60%), Gaps = 3/259 (1%)
Frame = +1
Query: 160 MAEPI-RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
M +P+ RV ++GAAGQI YS+L++IA+G + G QPV + +L++ + EGV MEL D
Sbjct: 1 MTKPVLRVCISGAAGQICYSVLFRIAAGDMLGYDQPVHIVMLEVPAALKAAEGVAMELVD 60
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
CA PLL+G T++ EAFKDV L GA PRK GMER +LL+ N IF+ QG A+++
Sbjct: 61 CAFPLLSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQIQGAAINEH 120
Query: 517 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 696
A+ ++LV+GNPANTNAL+ S IPK N TAM+RLD NRA Q+A K+GV +
Sbjct: 121 AKPTCRILVIGNPANTNALVLSTQLTKIPKTNVTAMSRLDHNRAVGQVAGKLGVRTNRIS 180
Query: 697 RVIIWGNHSSTQFPDASNAVAIVGGA--QKSVSEIINDDAYLKGAFVTTVQKRGAAVIXX 870
V + GNHS+T P V G ++ V ++ D ++KG FV V+ RG AVI
Sbjct: 181 NVWVAGNHSNTMVPIVDCGVIYDEGLKDKQPVKPMLPAD-WIKGEFVPCVRGRGTAVIEA 239
Query: 871 XXXXXXXXXXXXXXXHMKN 927
H+++
Sbjct: 240 RGHSSSASAANAAIDHVRD 258
>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 339
Score = 210 bits (512), Expect = 5e-53
Identities = 106/255 (41%), Positives = 150/255 (58%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 339
M EP RV++TGAAGQI Y L + IASG ++G ++PV LHL DI L + MEL DC
Sbjct: 1 MVEPARVLITGAAGQIGYVLSHWIASGELYG-ERPVILHLFDIPVAQNRLTALTMELQDC 59
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
A P LAG + T PE+AFKD+ AFLV ++P K G R DL+ +N IFK G+ L + A
Sbjct: 60 AFPHLAGYVATTEPEQAFKDIDCAFLVASVPMKSGQIRSDLIGSNSIIFKNTGEWLSQYA 119
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
+ VKVLV+GNP NTNA I +A ++ ENF++++ LDQNRA +A K+GV V D+
Sbjct: 120 KPTVKVLVIGNPDNTNAEIALLHAKNLKPENFSSLSLLDQNRAYHAIAEKLGVKVTDLHD 179
Query: 700 VIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXX 879
+++WGNH + D + A G + V++++ D+ Y + F + RG ++
Sbjct: 180 IVVWGNHGESMVADLTQATFEKDGKIQKVTDVL-DEKYREETFFKFISHRGWDIVEYRGF 238
Query: 880 XXXXXXXXXXXXHMK 924
HMK
Sbjct: 239 SSAASPTKASIQHMK 253
>UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Rep:
Malate dehydrogenase - Trypanosoma cruzi
Length = 332
Score = 206 bits (504), Expect = 5e-52
Identities = 114/231 (49%), Positives = 145/231 (62%), Gaps = 1/231 (0%)
Frame = +1
Query: 175 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
+VVV+GAAG++ Y+LL IA G + GP Q + L+LLDI M LEG+ EL DCA PLL
Sbjct: 9 KVVVSGAAGKVGYALLPLIAGGRMLGPNQHLQLNLLDIEAAMKCLEGIRAELMDCAFPLL 68
Query: 355 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 534
V+ T P AF++V A L G+ P K G R+DLL N IF E G+ L + A KD
Sbjct: 69 DRVVITHQPAVAFENVDIAILCGSFPAKPGTLRRDLLQKNAAIFSEHGRLLGELASKDCH 128
Query: 535 VLVVGNPANTNALICSKYA-PSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 711
V VVGNP NTNAL+ + I +N +A+TRLD NR+ + +A + V+DVK IIW
Sbjct: 129 VCVVGNPVNTNALVLLNASNGKIKPKNVSALTRLDHNRSLALVAERANAHVRDVKNCIIW 188
Query: 712 GNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 864
GNHS TQ PD ++A V G V E I DDAYL G F+TTVQ+RG +I
Sbjct: 189 GNHSGTQVPDVNSAT--VKGV--PVREAIKDDAYLDGEFMTTVQQRGYEII 235
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 205 bits (500), Expect = 1e-51
Identities = 108/234 (46%), Positives = 149/234 (63%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 339
M +P+ V+VTGAAGQI Y L ++IA+G +FG ++ V LHLL+I+P M LE VVMEL DC
Sbjct: 1 MTQPLHVLVTGAAGQIGYVLAFRIANGDLFG-ERDVVLHLLEISPAMKALEAVVMELHDC 59
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
P L V+ T++ EEAF+DV AFLVG+ P+K + D N I+ E G+AL A
Sbjct: 60 TFPHLLHVIGTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFA 119
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
+ VKVLV+G P NTNAL+ A ++ +NF AMTRLD NRA +A K+GV V +
Sbjct: 120 KPTVKVLVIGMPTNTNALVAMTAAVNLSPKNFCAMTRLDHNRAVYSIAQKLGVHHSKVYK 179
Query: 700 VIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAV 861
V+IWGN SS+Q PD SNA + + E ++++ Y+ F + + +RG V
Sbjct: 180 VVIWGNRSSSQIPDVSNAEYQDETGRHHILEKVSEE-YVNTEFSSDLAQRGNKV 232
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 202 bits (493), Expect = 1e-50
Identities = 102/253 (40%), Positives = 148/253 (58%)
Frame = +1
Query: 166 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 345
E +++ +TG AG +A + + SG VFG Q L LL++ + LEG+ M++ DCA
Sbjct: 5 EELKIAITGGAGNLASAFYPLLGSGQVFGSTQKFSLQLLELPEKLQELEGIKMQIQDCAF 64
Query: 346 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
PLL V +++P AFKD A +GAMPRK GMER DLL N IF +QGQ L++ A+
Sbjct: 65 PLLNNVTVSSDPAIAFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKS 124
Query: 526 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
VKVLVV NP+NTN + IP++NFT++ +LD NR S LA + + +K+VI
Sbjct: 125 TVKVLVVANPSNTNCATLAHQCTKIPQQNFTSLMQLDHNRCVSTLAREANTTIDQIKKVI 184
Query: 706 IWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXX 885
IWGNHS TQ+PD ++ +I+ G K SE + D +L+ A + VQ+RG ++
Sbjct: 185 IWGNHSLTQYPDMTH--SIING--KQASETFSKD-FLRNALIQQVQQRGGQILQLSRGAS 239
Query: 886 XXXXXXXXXXHMK 924
H++
Sbjct: 240 TISGAIAVKDHLR 252
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 183 bits (445), Expect = 7e-45
Identities = 102/258 (39%), Positives = 143/258 (55%)
Frame = +1
Query: 154 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 333
+ EP+ V++TGAAGQI Y+L + I G +F V LHL D+ M L+G+ MEL
Sbjct: 10 VNRTEPLHVLITGAAGQIGYNLCFLIGRGFLFDCD--VILHLYDLNDM--ALKGLSMELT 65
Query: 334 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 513
DC LP L G++ T AF +V A +V +PRK GM+R DL+ N ++ + G+AL
Sbjct: 66 DCCLPKLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGT 125
Query: 514 AARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 693
+ KDV+V+VV NPANTNA + K IP E+ TA+TRLDQNRA + +A ++G + V
Sbjct: 126 YSNKDVRVVVVANPANTNAYVICK-TSGIPPEHITALTRLDQNRATAFVANEVGCQPEFV 184
Query: 694 KRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVIXXX 873
+I+WGNHS+T PD S + K ++ I D AF V+ RG VI
Sbjct: 185 HNIIVWGNHSNTMQPDLSYSYLADQNGIKPLANCIED----FDAFTEKVRCRGEEVISTR 240
Query: 874 XXXXXXXXXXXXXXHMKN 927
H+K+
Sbjct: 241 KASSAGSAAHAICQHIKD 258
>UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 181 bits (440), Expect = 3e-44
Identities = 92/240 (38%), Positives = 145/240 (60%), Gaps = 10/240 (4%)
Frame = +1
Query: 157 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
K P+RV V+ A+G +AY +L + G VFG Q+ V ++LLD L+GV E+ D
Sbjct: 127 KKINPLRVCVSKASGPLAYGMLASLVQGEVFGFQEEVSIYLLDTPENQEALQGVAYEIED 186
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
CA PL GV T++P AFKD + L+ EG ++K+ L ++ ++F++ G+AL+
Sbjct: 187 CAWPLFRGVHITSDPAVAFKDASVVVLLDGKAINEGTDKKEYLLSHAKLFRDYGKALEAH 246
Query: 517 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 696
A+ D KVL G PAN + I SK+APSI K+NF +++R+++NRA+ +A ++ V +K
Sbjct: 247 AKPDCKVLTAGGPANFSTFIASKFAPSIQKKNFVSLSRIEENRAKGLIAKRLNVNTAGIK 306
Query: 697 RVIIWGNHSSTQFPDASNA------VAIVG----GAQKSVSEIINDDAYLKGAFVTTVQK 846
+I+WGN +PDAS+A AI G G + V E+++D+ +L G FV ++K
Sbjct: 307 DLIVWGNPGFNHYPDASHARVDGFDGAIWGPHVPGFTRPVPEMVHDNKWLSGEFVEVLKK 366
>UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase).; n=1;
Takifugu rubripes|Rep: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase). -
Takifugu rubripes
Length = 382
Score = 175 bits (427), Expect = 1e-42
Identities = 91/135 (67%), Positives = 104/135 (77%), Gaps = 1/135 (0%)
Frame = +1
Query: 157 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
+ AEPIRV+VTGAAGQIAYSLL+ IA G VFG QP+ L LLDI M+ VLEGVVMEL D
Sbjct: 90 RQAEPIRVLVTGAAGQIAYSLLFSIAKGDVFGKDQPIILLLLDITAMLPVLEGVVMELQD 149
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
CALPLL ++ T E AFKD+ AA LVG+MPRKEGMERKDLL ANV IFK QG AL+K
Sbjct: 150 CALPLLRDIIATDMEEVAFKDLDAAILVGSMPRKEGMERKDLLKANVAIFKSQGSALEKF 209
Query: 517 ARKDVKVLV-VGNPA 558
++K VKV + G PA
Sbjct: 210 SKKTVKVAMRCGVPA 224
Score = 85.0 bits (201), Expect = 2e-15
Identities = 38/91 (41%), Positives = 55/91 (60%)
Frame = +1
Query: 655 QLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVT 834
++A + GVP VK VIIWGNHSSTQ+PD + + + G++ + + I D+A+LKG F+
Sbjct: 215 KVAMRCGVPATHVKNVIIWGNHSSTQYPDVHHCMVNMSGSELTCFDAIKDEAWLKGEFIA 274
Query: 835 TVQKRGAAVIXXXXXXXXXXXXXXXXXHMKN 927
TVQ+RGAAVI HM++
Sbjct: 275 TVQQRGAAVIKARKLSSAMSAAKAICDHMRD 305
>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
acosta|Rep: Malate dehydrogenase - Hypotrichomonas
acosta
Length = 318
Score = 150 bits (364), Expect = 4e-35
Identities = 75/178 (42%), Positives = 110/178 (61%)
Frame = +1
Query: 217 LLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFK 396
+ ++IA+G + G ++ V LHLL++ + EG+ +EL DCA L + T EEA K
Sbjct: 1 MAFRIANGDLLGNRR-VCLHLLELPVALKACEGLALELEDCAFQNLEKTIVTDKLEEACK 59
Query: 397 DVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALI 576
D+ AFLV ++P K G R +LL N IFK G+AL + A+ V+ LVVGNP N+N L+
Sbjct: 60 DIDIAFLVASVPLKPGEHRVNLLTKNTPIFKAIGEALSEYAKPTVRALVVGNPVNSNCLV 119
Query: 577 CSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASN 750
AP + ENF+ M LD NR+ S++A+ + VP+ V V +WGNH+ TQ PD ++
Sbjct: 120 AMLNAPKLSAENFSCMCTLDHNRSVSRIASHLKVPIDHVYHVAVWGNHAETQVPDITH 177
>UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella
chejuensis KCTC 2396|Rep: Malate dehydrogenase - Hahella
chejuensis (strain KCTC 2396)
Length = 193
Score = 117 bits (281), Expect = 5e-25
Identities = 67/161 (41%), Positives = 89/161 (55%)
Frame = +1
Query: 445 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 624
M+R L N IF EQG+AL K A+ VK LVVGNPANTNALI A +P F+A+
Sbjct: 1 MDRMQQLQENPSIFVEQGKALGKVAKDTVKTLVVGNPANTNALIAWANARYLPHHQFSAL 60
Query: 625 TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIIND 804
RLD NRA L+ KIG+ + +KR+ IWGNH+ST FPDAS+ + I G + D
Sbjct: 61 MRLDHNRALGFLSRKIGINPRRIKRLTIWGNHASTLFPDASH-LRIDG----QPIRMALD 115
Query: 805 DAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXXHMKN 927
+ + + VQ+RG AVI H+++
Sbjct: 116 MNWYRDIMIDQVQQRGTAVISCKGRTSSSSAAQAIIDHLRD 156
>UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5362-PA - Nasonia vitripennis
Length = 358
Score = 116 bits (280), Expect = 7e-25
Identities = 78/220 (35%), Positives = 114/220 (51%), Gaps = 5/220 (2%)
Frame = +1
Query: 175 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
RVV+T A IA SL Y+I S +FG Q + L L D +L+ V +E+ CA LL
Sbjct: 19 RVVITEATSFIARSLAYRILSDEIFGADQEIVLSLYDSGEQAMLLQTVAIEITACAPNLL 78
Query: 355 AGVLPTANPEEAFKDVAAAFLVGA-----MPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
V+ +++ AF F +G + + ++ +V K+ AL+K A
Sbjct: 79 KDVVYSSDTSLAFAGADWVFFIGKSRDYNFSKSQELQDDPFFIESVLETKKMAIALEKFA 138
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
+ DVK++ +GN T+A + S+YAPSIPK N T +T + Q A S +A K G DVK
Sbjct: 139 KIDVKIITLGN---TSARLISEYAPSIPKNNITGVTLVLQRLAASAIAKKTGRLPSDVKN 195
Query: 700 VIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 819
+IIWG +S + FP +A +KSV I DD + K
Sbjct: 196 LIIWGTNSRSVFPYCGHAKF---SDEKSVINEICDDKWFK 232
>UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1;
Branchiostoma floridae|Rep: Putative uncharacterized
protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 522
Score = 110 bits (264), Expect = 6e-23
Identities = 71/244 (29%), Positives = 126/244 (51%), Gaps = 9/244 (3%)
Frame = +1
Query: 157 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
+ ++P+ V V AA AY +L + +G + ++ + LHL D + L+G+ ME+ D
Sbjct: 127 RQSKPLHVCVINAARSPAYHVLPSLVNGKILREEE-IALHLHDSEENLEKLKGLEMEVFD 185
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
+ P L + T + AF++ A ++ + + + V +K +A+++
Sbjct: 186 LSFPFLKEISVTTDLPTAFQNAHIAIVLDDFDQGGKEDAIGDMETKVSFYKRVAEAINQT 245
Query: 517 ARKDVKVLVVGN-PANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 693
A KD++VLV G P N+ I + PSIP++N A+ ++ + +A+S LA ++ V V
Sbjct: 246 ASKDIRVLVAGTGPLNSLVSILIDHTPSIPRQNIAAVAQVKERQAKSLLAKRLTVNSAGV 305
Query: 694 KRVIIWGNHSSTQFPDASNA------VAIVG--GAQKSVSEIINDDAYLKGAFVTTVQKR 849
VI+WGN T + D S A AI G SVSE+++D+ +L+G F+ +Q R
Sbjct: 306 CDVIVWGNVGGTTYTDVSRARVHGYDGAIWGPPSYSCSVSEMVHDNKWLEGEFLEQLQSR 365
Query: 850 GAAV 861
+
Sbjct: 366 SHTI 369
>UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble); n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble) - Monodelphis domestica
Length = 655
Score = 101 bits (242), Expect = 3e-20
Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 1/200 (0%)
Frame = +1
Query: 157 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
+M P++V +TGA+ Y L+ +ASG VFG ++ + ++LL L G+VME D
Sbjct: 261 EMINPLQVWITGASCPTCYHLIPILASGEVFGLEEEISINLLSSTYNEDNLRGLVMESED 320
Query: 337 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 516
ALPLL + EAF + ++ + E +D + I + G +DK
Sbjct: 321 LALPLLRNISLCTEINEAFLEAHVIVILNDIIEDESEPLEDRIRDRFPICQLYGSLIDKN 380
Query: 517 ARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 693
A ++VKV+V G N + ++ PS+ N A+ + +N A++ LA K+ V
Sbjct: 381 ANENVKVIVAGKTFLNLTTSLIIQHTPSVNPRNIIAVAMIVENEAKAMLARKLKTLPSYV 440
Query: 694 KRVIIWGNHSSTQFPDASNA 753
K VIIWGN + ++ D A
Sbjct: 441 KDVIIWGNITGFRYIDLKKA 460
>UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 553
Score = 97.9 bits (233), Expect = 3e-19
Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 11/247 (4%)
Frame = +1
Query: 154 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 333
+ + P++V +T ++ IAY ++ +IA G V G V + LL +EG ME+
Sbjct: 120 LSRSTPLQVCITNSSSPIAYHMVNEIARGDVLGHDNEVSIRLLTKPEDKDYVEGQCMEVF 179
Query: 334 DCALPLLAGVLPTANPEEAFKDVAAAFLVG--AMPRKEGMERKDLLAANVRIFKEQGQAL 507
D A PLL GV + A V A + + +E + + F G+ L
Sbjct: 180 DLACPLLRGVKVYTDATAALTGVHVAVFLDEFCLMEEENAKLGGVSQEGCAQFALYGRIL 239
Query: 508 DKAARKDVKVLVVG-NPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPV 684
++ A +DVKVL+ G N +AL+ AP I ++N RL +NRA++ +A KI V
Sbjct: 240 NQYAEQDVKVLIGGRGKLNFSALMLKHNAPRIARQNIIITPRLQENRAKAAIARKINVNT 299
Query: 685 KDVKRVIIWGNHSSTQFPDASNA------VAIVGGA--QKSVSEIINDDAYLKGAFVTTV 840
V +IIWGN D S A AI G + + V+E+++D+ +L+ + +
Sbjct: 300 AGVADLIIWGNIGGITHFDISQARVYKYEGAIWGPSSFSRPVTEVVHDEKWLQTEYPQLL 359
Query: 841 QKRGAAV 861
Q A+
Sbjct: 360 QNHPDAL 366
>UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21;
Amniota|Rep: Malate dehydrogenase 1B - Homo sapiens
(Human)
Length = 518
Score = 88.2 bits (209), Expect = 3e-16
Identities = 57/192 (29%), Positives = 92/192 (47%), Gaps = 1/192 (0%)
Frame = +1
Query: 169 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 348
P++V +T A+ Y+L+ + SG VFG + + L D L+ +V+E D A P
Sbjct: 131 PLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASP 190
Query: 349 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 528
+L V EEAF+ ++ KE +D L + V + + G ++K A +
Sbjct: 191 VLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLEDCLRSRVPLCRLYGYLIEKNAHES 250
Query: 529 VKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
V+V+V G N ++ +YAP I N A+ + A++ LA K+ +K VI
Sbjct: 251 VRVIVGGRTFVNLKTVLLMRYAPRI-AHNIIAVALGVEGEAKAILARKLKTAPSYIKDVI 309
Query: 706 IWGNHSSTQFPD 741
IWGN S + D
Sbjct: 310 IWGNISGNNYVD 321
>UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep:
Zgc:153922 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 447
Score = 85.0 bits (201), Expect = 2e-15
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 9/245 (3%)
Frame = +1
Query: 154 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 333
+K P+ + ++ A + YSL+ + + +F + LHL+D + +L+ + ME
Sbjct: 126 LKSLRPLHIWISSALNPVCYSLIPHLFTPGLFSGLPILSLHLMDTSGSEEMLQALKMETV 185
Query: 334 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 513
D A+P L N E+ KD A F GQ ++
Sbjct: 186 DLAIPRLHEPAGEYNDEQNDKDQVAEH-----------------------FHRYGQLIET 222
Query: 514 AARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKD 690
A+KDV+VLV G+ N + + APSI NF AMT + A++QLA K+ V D
Sbjct: 223 NAQKDVRVLVAGDFFINMKCSLLIENAPSIDSRNFVAMTTQLEYEARTQLAQKLSVKTSD 282
Query: 691 VKRVIIWGNHSSTQFPDASNAV------AIVG--GAQKSVSEIINDDAYLKGAFVTTVQK 846
+ VI+WGN S + D A AI G G + V E+I D +LK F + + K
Sbjct: 283 ITNVIVWGNISGSFHIDLQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWLKTDFRSLLHK 342
Query: 847 RGAAV 861
A +
Sbjct: 343 HRATI 347
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 73.3 bits (172), Expect = 8e-12
Identities = 60/193 (31%), Positives = 85/193 (44%)
Frame = +1
Query: 175 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
++ + GAAG I S + Q A+ P L L D P LEGV E+ C L
Sbjct: 8 KLTIVGAAGMIG-SNMAQTAAMMRLTPN----LCLYD--PFAVGLEGVAEEIRHCGFEGL 60
Query: 355 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 534
+ T++ +EA D G PRKEGM R+DLL N I + G+ +
Sbjct: 61 -NLTFTSDIKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKH 119
Query: 535 VLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWG 714
V+++ NPA+ L+ Y+ P + T + LD R QS+LA G+ V +G
Sbjct: 120 VIIIFNPADITGLVTLIYSGLKPSQ-VTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTYG 178
Query: 715 NHSSTQFPDASNA 753
H AS A
Sbjct: 179 GHGEQMAVFASTA 191
>UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD
(soluble); n=1; Takifugu rubripes|Rep: malate
dehydrogenase 1B, NAD (soluble) - Takifugu rubripes
Length = 441
Score = 72.1 bits (169), Expect = 2e-11
Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 15/242 (6%)
Frame = +1
Query: 184 VTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGV 363
++ A + L+ + S VF + +HLLD+ VL + EL AL LL V
Sbjct: 122 ISSALSSTSQFLMSSLISADVFPNISTIDVHLLDLDGDEEVLHHLKNELEHQALHLLHQV 181
Query: 364 LPTANPEEAFKDVAAAFLVGAM------PRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
+ E+AF+ L+ + E +K + A ++E G+ +D +K
Sbjct: 182 TIHTDLEQAFQKADVIILLDELWCDDIATVDERELKKQKIDAISERYREYGRLIDTQTKK 241
Query: 526 DVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 702
+VKV+V G N + Y SI A+ +N A++ +A K+ V DV+ V
Sbjct: 242 EVKVIVSGESFVNLRCSLLLDYTHSIHSHQIVALATQLENEARAIVAKKLNVRPADVRDV 301
Query: 703 IIWGNHSSTQFPDASNA-VAIVGGAQKS-------VSEIINDDAYLKGAFVTTVQKRGAA 858
I+WGN S + + D V G K IIND +++ F V+ R AA
Sbjct: 302 IVWGNISGSFYVDLQKTKVFNYDGPVKGPEFFSLPAQNIINDRTWIETDFQELVRSRRAA 361
Query: 859 VI 864
V+
Sbjct: 362 VV 363
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 65.7 bits (153), Expect = 2e-09
Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = +1
Query: 385 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANT 564
E D + + +PRK GM R DLL N RI + + + K A V V+VV NP +
Sbjct: 83 EVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAV-VIVVSNPLDE 141
Query: 565 NALICSKYAPSIPKENFTAMT-RLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPD 741
+ ++ PK LD R +A ++GVP++ V R + G+H T P
Sbjct: 142 MTAL-TQLVTGFPKNRVMGQAGMLDTARFSHFVAEELGVPIRAV-RTLTLGSHGDTMVPV 199
Query: 742 ASNAVAIVGGAQKSVSEII 798
S + G Q+ +++++
Sbjct: 200 PSQCFVTIDGEQRRLADLV 218
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 65.3 bits (152), Expect = 2e-09
Identities = 57/183 (31%), Positives = 84/183 (45%), Gaps = 1/183 (0%)
Frame = +1
Query: 175 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
++ + GAAG I S + Q A P + L D P LEGV EL CA +
Sbjct: 8 KLTIVGAAGMIG-SNMAQTALMMKLTPN----ICLYD--PYAPALEGVAEELYHCAFEGV 60
Query: 355 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 534
+ T++ +EA G RK GM R+DLL N I + G+ + + DVK
Sbjct: 61 -NLTYTSDIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYC-PDVK 118
Query: 535 -VLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 711
V+VV NPA+ LI YA P + + + LD R Q++L + +P ++ +
Sbjct: 119 HVVVVFNPADITGLIVLLYAGLKPSQ-VSTLAALDSTRLQNELVKYLHIPASEIVNCRTY 177
Query: 712 GNH 720
G H
Sbjct: 178 GGH 180
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 60.5 bits (140), Expect = 6e-08
Identities = 64/224 (28%), Positives = 95/224 (42%), Gaps = 7/224 (3%)
Frame = +1
Query: 145 YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 324
YG K+ +V V GAAG I L I + LHL DIA + +GV
Sbjct: 75 YG-FKINASYKVAVLGAAGGIGQPLSLLIKMSPLVST-----LHLYDIANV----KGVAA 124
Query: 325 ELADCALPLLAGVLPTANPEE---AFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQ 495
+L+ C P + V P E KDV + +PRK GM R DL N I K
Sbjct: 125 DLSHCNTP--SQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTL 182
Query: 496 GQALDKAARKDVKVLVVGNPANTN----ALICSKYAPSIPKENFTAMTRLDQNRAQSQLA 663
+A+ + + + ++ NP N+ A + K PK+ F +T LD RA + ++
Sbjct: 183 VEAVAENC-PNAFIHIISNPVNSTVPIAAEVLKKKGVYDPKKLF-GVTTLDVVRANTFVS 240
Query: 664 AKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEI 795
K + + DV +I G+ T P S V + + E+
Sbjct: 241 QKKNLKLIDVDVPVIGGHAGITILPLLSKTKPSVNFTDEEIQEL 284
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 59.3 bits (137), Expect = 1e-07
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 3/159 (1%)
Frame = +1
Query: 271 LHLLDIAPMMGVLEGVVMELADCA--LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 444
L L D+ P G+ +G ++L + L + +L T N E KD + + RKEG
Sbjct: 28 LILYDVVP--GIPQGKALDLKHFSTILGVNRNILGT-NQIEDIKDADIIVITAGVQRKEG 84
Query: 445 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 624
M R+DL+ N +I K +++ K V+ V NP + + K++ ++P E M
Sbjct: 85 MTREDLIGVNGKIMKSVAESVKLHCSK-AFVICVSNPLDIMVNVFHKFS-NLPHEKICGM 142
Query: 625 TR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 738
LD +R S +A K+ V +DV VI+ G H P
Sbjct: 143 AGILDTSRYCSLIADKLKVSAEDVNAVIL-GGHGDLMVP 180
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/123 (30%), Positives = 59/123 (47%)
Frame = +1
Query: 385 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANT 564
E K + +PR+EGM R+DLL N++I K+ A+ + A KD ++VV NP +T
Sbjct: 84 EELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYA-KDSIIIVVSNPVDT 142
Query: 565 NALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDA 744
K P+ LD R ++ + KIG+ D+ R ++ G H P
Sbjct: 143 LTYATIKLTGFEPRRVIGMAGVLDSARFKNFVKEKIGISNADI-RTLVLGTHGDLMVPVT 201
Query: 745 SNA 753
S++
Sbjct: 202 SHS 204
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 56.4 bits (130), Expect = 1e-06
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +1
Query: 388 AFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPA 558
+ KDVA + +V PR G R DL N RI + + A D K+++V NP
Sbjct: 67 SLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIA-PDTKIIMVTNPV 125
Query: 559 NTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 738
+ + KY+ P + F T LD R +S +A+ V V +V II G H + P
Sbjct: 126 DVMTCVALKYSGLKPNQVFGLGTHLDSMRLKSLIASYFKVHVSEVHTRII-GEHGDSMVP 184
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 56.0 bits (129), Expect = 1e-06
Identities = 54/197 (27%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +1
Query: 160 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 339
MA P ++ + GA GQI +L + +A + + L DIA G EG +++A+
Sbjct: 1 MARP-KIALIGA-GQIGGTLAHLVALKELGD------VVLFDIAE--GTPEGKALDIAES 50
Query: 340 ALPLLAGVLPTANPEEAFKDVAAA---FLVGAMPRKEGMERKDLLAANVRIFKEQGQALD 510
G +++ D+A A + +PRK GM R DLL N+++ K G+ +
Sbjct: 51 GPS--EGFDAKLKGTQSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIR 108
Query: 511 KAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVK 687
A D V+ + NP + +++ +P M LD R + LA + V +K
Sbjct: 109 DNA-PDAFVICITNPLDAMVWALQQFS-GLPANKVCGMAGVLDSARFRHFLAEEFNVSMK 166
Query: 688 DVKRVIIWGNHSSTQFP 738
DV ++ G H T P
Sbjct: 167 DVTAFVL-GGHGDTMVP 182
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%)
Frame = +1
Query: 373 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 552
+N KD + +PRK GM R DLLA N +I + G+A+ K + V+ + N
Sbjct: 217 SNDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAI-KQYCPNAFVICITN 275
Query: 553 PANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 729
P + I + +P M LD R ++ L+ ++ V V D+ ++ G H T
Sbjct: 276 PLDVMVYILREKC-GLPPHKVCGMAGVLDSARLRTFLSERLNVSVDDI-HALVMGGHGDT 333
Query: 730 QFP 738
P
Sbjct: 334 MVP 336
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 54.4 bits (125), Expect = 4e-06
Identities = 40/121 (33%), Positives = 55/121 (45%)
Frame = +1
Query: 415 LVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAP 594
L +PRK R DL N RI K + + + A + + +LVV NP + + KY+
Sbjct: 79 LTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAI-LLVVTNPVDIMTTVALKYSG 137
Query: 595 SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGA 774
+P F T LD R ++ LA V V ++ II G H T P S VGG
Sbjct: 138 MMPHRVFGLGTHLDSMRLKACLAEFFNVHVSEIHTRII-GEHGDTMVPMWS--ATTVGGI 194
Query: 775 Q 777
Q
Sbjct: 195 Q 195
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 53.2 bits (122), Expect = 9e-06
Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 3/196 (1%)
Frame = +1
Query: 172 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 351
+++ V GA G + S+ Y +A V + L+DI + + + + A C +
Sbjct: 1 MKISVIGA-GNVGASIAYALAMRGVCDE-----IALVDIFGDVARAKAIDIAQAGC---V 51
Query: 352 LAGVLPTANPEEAFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKAAR 522
G L TA ++ F + A+ +V PRKEG R+DLL N ++ K+ Q + K A
Sbjct: 52 FCGCLSTAGGDD-FALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAP 110
Query: 523 KDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 702
+ V++V NP + +Y+ LD R + ++A+ + KDV
Sbjct: 111 NAI-VIIVTNPLDVMVWTVLRYSGFDRSRVIGMAGELDSARCRYEIASLKDISAKDVSAK 169
Query: 703 IIWGNHSSTQFPDASN 750
++ G H+ A N
Sbjct: 170 VL-GAHNDKMIVSAKN 184
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 52.8 bits (121), Expect = 1e-05
Identities = 40/138 (28%), Positives = 61/138 (44%), Gaps = 1/138 (0%)
Frame = +1
Query: 361 VLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVL 540
V P E + + PR+ GM R+DLL AN+RI + + A D V+
Sbjct: 73 VTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYA-PDAIVI 131
Query: 541 VVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGN 717
VV NP + + K + PK M LD R ++ ++ ++ V KD+ +I G
Sbjct: 132 VVTNPVDVMTYVAYKLL-NFPKNRVMGMAGVLDSARFKTFISEELMVSPKDIHAYVI-GG 189
Query: 718 HSSTQFPDASNAVAIVGG 771
H P S ++ VGG
Sbjct: 190 HGDEMVPLIS--ISNVGG 205
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 52.4 bits (120), Expect = 2e-05
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 3/195 (1%)
Frame = +1
Query: 163 AEPIRVVVTGAA---GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 333
++P++VV+ GA AY+LL A+ + L+D+ EG VM+L
Sbjct: 10 SKPVKVVIVGAGYVGSTTAYTLLMNRAAAEIV---------LIDVDK--DKTEGEVMDLV 58
Query: 334 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 513
A P L A E K + L +K G R +L +N IFKE + +
Sbjct: 59 HAA-PFLHQTRIWAGDYEDCKGASVIILTAGANQKPGQSRMELAQSNWGIFKEIVPKVVQ 117
Query: 514 AARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 693
A D +LV NP + K++ + T LD R +L + + + +
Sbjct: 118 HASPDALLLVSANPVDVMTYAAVKFSGFPAHSVIGSGTSLDSARFAGELGKHLNIDPRSL 177
Query: 694 KRVIIWGNHSSTQFP 738
V+I G H ++ P
Sbjct: 178 HAVVI-GEHGESELP 191
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 52.0 bits (119), Expect = 2e-05
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 1/123 (0%)
Frame = +1
Query: 373 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 552
AN A + + +PRK GM R DLL N+++ ++ G + K A + V+ + N
Sbjct: 63 ANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYA-PEAFVICITN 121
Query: 553 PANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 729
P + K++ +P M LD R + L+ + V V+DV ++ G H +
Sbjct: 122 PLDAMVWALQKFS-GLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVL-GGHGDS 179
Query: 730 QFP 738
P
Sbjct: 180 MVP 182
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 51.6 bits (118), Expect = 3e-05
Identities = 63/204 (30%), Positives = 93/204 (45%), Gaps = 20/204 (9%)
Frame = +1
Query: 172 IRVVVTGAAGQIAY--SLLYQIASGAVFGPQQPVF-LHLLDIAPMMGVLEGVVMELADCA 342
+RV V GAAG I SLL + V G L L D+A L GV +L+
Sbjct: 24 VRVAVLGAAGGIGQPLSLLLKTQLAQVLGDANASLELALYDVAA--DALAGVAADLSHVN 81
Query: 343 LPL-LAGVLPTANP-EEAFKDV---AAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQA 504
P+ ++ +P++ EEA ++ A+ ++ A +PRK GM R DL+ N I K +
Sbjct: 82 TPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKG 141
Query: 505 LDKAA-RKDVKVLVVGNPANTNALIC---------SKYAPSIPKE-NFTAMTRLDQNRAQ 651
+ A + V VLV+ NP N+ + +K AP E +T+LD RA
Sbjct: 142 IAGACDLEKVFVLVISNPVNSLVPVMVRQLIRHAEAKQAPHAGVERRVFGVTQLDMVRA- 200
Query: 652 SQLAAKIGVPVKDVKRVIIWGNHS 723
S +G +V V + G HS
Sbjct: 201 SAFVRSLGELGNEVPSVPVIGGHS 224
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 48.8 bits (111), Expect = 2e-04
Identities = 53/205 (25%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Frame = +1
Query: 151 NIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHL-LDIAPM-MGVLEGVVM 324
N + E +++ V GAAG I SL + S A F H+ L + + + G
Sbjct: 40 NAQEKEILKISVLGAAGGIGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAA 99
Query: 325 ELADCALPLLAGV-LP---TANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKE 492
+L+ P+ P + + + + +PRK GM R DL+ N +I K
Sbjct: 100 DLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKS 159
Query: 493 QGQALDK-AARKDVKVLVVGNPAN------TNALICS-KYAPSIPKENFTAMTRLDQNRA 648
G+ + K V VLV+ NP N TN LI S S + +T+LD R+
Sbjct: 160 LGEDIAKYCDLNKVHVLVISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVRS 219
Query: 649 QSQLAAKIGVPVKDVKRVIIWGNHS 723
+ + G + + G HS
Sbjct: 220 STFVQQLNGFKSNTSPVIPVIGGHS 244
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 48.8 bits (111), Expect = 2e-04
Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 1/141 (0%)
Frame = +1
Query: 394 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 573
KD + +P+K G R DL+ N +IFK+ + + + + L+ NP +
Sbjct: 72 KDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGI-FLIATNPVDILTY 130
Query: 574 ICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASN 750
+ K + +PKE T LD R + L + V ++V I+ G H T+ P S+
Sbjct: 131 VTWKES-GLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIV-GEHGDTELPVWSH 188
Query: 751 AVAIVGGAQKSVSEIINDDAY 813
A G QK + + N++ Y
Sbjct: 189 ATI---GVQKLETILANNEQY 206
>UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to
tetratricopeptide repeat domain 21B; n=1; Apis
mellifera|Rep: PREDICTED: similar to tetratricopeptide
repeat domain 21B - Apis mellifera
Length = 1491
Score = 47.2 bits (107), Expect = 6e-04
Identities = 32/93 (34%), Positives = 48/93 (51%)
Frame = +1
Query: 145 YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 324
Y IK E + +VT +IA S LY+I + VFG Q VF+ L +++ LE + +
Sbjct: 1214 YPRIKK-EILEKLVTDGTTEIARSFLYRILTDDVFGKNQCVFVSLYELSTKTMFLESLAI 1272
Query: 325 ELADCALPLLAGVLPTANPEEAFKDVAAAFLVG 423
EL + LL+G+ + N E FKD +G
Sbjct: 1273 ELYSFSPKLLSGISYSNNVFE-FKDADVVICIG 1304
>UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1;
Medicago truncatula|Rep: Putative uncharacterized
protein - Medicago truncatula (Barrel medic)
Length = 165
Score = 47.2 bits (107), Expect = 6e-04
Identities = 27/62 (43%), Positives = 34/62 (54%)
Frame = +1
Query: 199 GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTAN 378
GQI +L IA G + G Q V LH+LDI P + L+GV MEL D + V +AN
Sbjct: 24 GQIGDALAPMIARGMMLGTNQHVILHMLDIEPTLEALKGVKMELIDVDVAAAGYVDKSAN 83
Query: 379 PE 384
E
Sbjct: 84 IE 85
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 46.8 bits (106), Expect = 8e-04
Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 1/189 (0%)
Frame = +1
Query: 175 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
++ + G +G + + + GA+ + + L DI GV + A +P+L
Sbjct: 4 KIAIIGGSGNVGSHIAFL---GAMRHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPIL 60
Query: 355 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 534
+ N E + + PR M R DLL N I +E + + A + +
Sbjct: 61 ---IKGCNSYEEIAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSL- 116
Query: 535 VLVVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIW 711
++VV NP + L+ +++ KE M LD R + +G K ++ +I
Sbjct: 117 LIVVSNPLDAMCLVAKQWS-KFEKERVIGMAGILDSARLTYESKVMLGDFNKHIQSYVI- 174
Query: 712 GNHSSTQFP 738
G+HS P
Sbjct: 175 GSHSDDMLP 183
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 45.6 bits (103), Expect = 0.002
Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 2/158 (1%)
Frame = +1
Query: 271 LHLLDIAPMMGVLEGVVMELADC--ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 444
LHL+ + G V++++D A + + +A+ E + G +PR
Sbjct: 29 LHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVYGSRIVVITAG-VPRTAD 87
Query: 445 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 624
M+R DL N RI + + + + A + +LVV NP + + +Y+ P F
Sbjct: 88 MDRDDLAFKNGRIVADYARQIARFAPDSI-ILVVTNPVDVMTYVALRYSGFHPSRVFGLG 146
Query: 625 TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 738
LD R ++ +A V V +V +I G H P
Sbjct: 147 NHLDSLRLKNYMARHFNVHVSEVHTRVI-GQHGPYMVP 183
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 44.8 bits (101), Expect = 0.003
Identities = 34/139 (24%), Positives = 61/139 (43%)
Frame = +1
Query: 277 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 456
L D+ P + + A AL + +L T N ++ + PRK GM R+
Sbjct: 31 LYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDD-ISGADIVVITAGKPRKPGMSRR 89
Query: 457 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 636
DL N +I + + L K K ++V NP + A + KY+ + + +++
Sbjct: 90 DLFIDNAKIMIDLAKKLPK-KNKGAMYIMVANPVDMMASVFMKYS---GENTISTGNQVE 145
Query: 637 QNRAQSQLAAKIGVPVKDV 693
R +S +A K+ +P +V
Sbjct: 146 TMRMRSYIAKKLNIPAYEV 164
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 44.8 bits (101), Expect = 0.003
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +1
Query: 310 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFL-VGAMPRKEGMERKDLLAANVRIF 486
EG M+L L+ G+ A A + L GA + R LL N IF
Sbjct: 43 EGEAMDLMH-GQQLVGGITCRAVEYAALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIF 101
Query: 487 KEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAA 666
+E LDK A + V V NP + IC + + + T LD R ++ L
Sbjct: 102 REIIIQLDKHAPNAILV-VATNPVDVLTYICQELSSRPNRRILGTGTLLDTARFRALLGR 160
Query: 667 KIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEII 798
GV + V I+ G H ++ P SNA +GG QK E +
Sbjct: 161 HYGVDPRSVHAYIL-GEHGDSEVPIWSNAT--IGG-QKIRGETV 200
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 44.4 bits (100), Expect = 0.004
Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 11/242 (4%)
Frame = +1
Query: 169 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 348
P +V V G G++ + Y +A V G + V L+D P G+ +GV+ ++ A
Sbjct: 5 PYKVAVIGT-GRVGATFAYTMA--IVPGVARMV---LVDAVP--GLSKGVMEDIKHAAAV 56
Query: 349 LLAGVLPTANPEEAFKDVAAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
+ A + + + A A ++ A PRK M R+DL N +I ++ G L +
Sbjct: 57 FRRSIQVEAYDDVSKVENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKL-RDRNP 115
Query: 526 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
+V+ NP + +I S + T T LD R +S ++ + P+ + +
Sbjct: 116 GAFYMVITNPVDVMTMILSDVIGNKGTVIGTG-TSLDTYRFRSAVSELLNEPIAAIDGYV 174
Query: 706 IWGNHSSTQFPDASNAVAIVG----------GAQKSVSEIINDDAYLKGAFVTTVQKRGA 855
+ G H F A + V + G G S S I + Y+K T + K+GA
Sbjct: 175 V-GEHGEEAFV-AWSTVTVKGVPIDEYIKEKGLDLSRSRI---EEYVKEVAATIIAKQGA 229
Query: 856 AV 861
+
Sbjct: 230 TI 231
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 44.4 bits (100), Expect = 0.004
Identities = 46/215 (21%), Positives = 89/215 (41%)
Frame = +1
Query: 166 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 345
+PI++ + GA G + S LY + + ++DI P +G + D +
Sbjct: 2 KPIKIALIGA-GNVGNSFLYAAMNQGLASEYG-----IIDINPDFA--DGNAFDFEDASA 53
Query: 346 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 525
L + + + KD + P+K G R +L+A N+RI +E + ++
Sbjct: 54 SLPFPISVSRYEYKDLKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFS 113
Query: 526 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 705
+ + +V NP + + ++ + T LD R Q +A + V V+ +
Sbjct: 114 GISI-IVANPVDIITRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVSPNSVQAYV 172
Query: 706 IWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDA 810
+ G H + F SN + I G + S++ D+
Sbjct: 173 M-GEHGDSSFVAYSN-IKIAGECFCAYSKLTGIDS 205
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 44.0 bits (99), Expect = 0.006
Identities = 53/194 (27%), Positives = 82/194 (42%), Gaps = 2/194 (1%)
Frame = +1
Query: 178 VVVTGAAGQ-IAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 354
+V GA G IAYS+L Q L L+DI +EG VM+L +P +
Sbjct: 25 IVGAGAVGMAIAYSMLIQNTFDE---------LVLVDIDRRK--VEGEVMDLVH-GIPFV 72
Query: 355 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQ-GQALDKAARKDV 531
+ A + V + ++EG R L+ NV IF+ G+ ++ +
Sbjct: 73 EPSVVRAGTLADCRGVDVVVITAGARQREGETRLSLVQRNVEIFRGLIGEIMEHCP--NA 130
Query: 532 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 711
+LVV NP + + K A P + T LD R + LA ++ V + + II
Sbjct: 131 ILLVVSNPVDVMTYVAMKLAGLPPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYII- 189
Query: 712 GNHSSTQFPDASNA 753
G H ++ P S A
Sbjct: 190 GEHGDSEVPVWSRA 203
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 43.6 bits (98), Expect = 0.007
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 1/155 (0%)
Frame = +1
Query: 310 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMP-RKEGMERKDLLAANVRIF 486
EG ++L A + + + ++ KD ++P R R ++ N+ I
Sbjct: 39 EGDALDLTHAAALVDSNIKISSGEIADSKDSDVIIFTASVPFRYPNQTRLEMGIDNMPIL 98
Query: 487 KEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAA 666
++ L KA+ + V++V NP + A + PK T +D R ++ L+
Sbjct: 99 RDWMPGLAKASPNAI-VVMVSNPVDALAYETIRLTGFDPKRVIGTGTLVDSIRYRALLST 157
Query: 667 KIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGG 771
++ + +D+ R I G H TQF A++++A+ GG
Sbjct: 158 ELKIHAQDI-RAYILGEHGDTQF--AASSIAMTGG 189
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 43.6 bits (98), Expect = 0.007
Identities = 39/153 (25%), Positives = 65/153 (42%)
Frame = +1
Query: 277 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 456
L+DIA + V E + + A + ++ A+ K + + RK GM R
Sbjct: 30 LVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGAD-YSLLKGSEIIVVTAGLARKPGMTRL 88
Query: 457 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 636
DL N I K+ + + + A + K+LVV NP + I K + E F +LD
Sbjct: 89 DLAHKNAGIIKDIAKKIVENAPES-KILVVTNPMDVMTYIMWKESGKPRNEVFGMGNQLD 147
Query: 637 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQF 735
R + +L ++++R I G H + F
Sbjct: 148 SQRLKERL---YNAGARNIRRAWIIGEHGDSMF 177
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 43.6 bits (98), Expect = 0.007
Identities = 42/148 (28%), Positives = 60/148 (40%)
Frame = +1
Query: 310 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFK 489
EG M+L A PL + KD A + +K G R DLL AN+ IFK
Sbjct: 59 EGEAMDLNHAA-PLSHETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFK 117
Query: 490 EQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAK 669
E + + K KD +LV NP + K + + T +D R Q +
Sbjct: 118 EILREVTKYT-KDAILLVATNPVDVLTYATLKLTGFPAERVIGSGTIIDTARFQYLIGKL 176
Query: 670 IGVPVKDVKRVIIWGNHSSTQFPDASNA 753
G+ + V II G H ++ S+A
Sbjct: 177 YGLDPQSVNADII-GEHGDSELAVWSHA 203
>UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein
NCU04826.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU04826.1 - Neurospora crassa
Length = 1422
Score = 42.7 bits (96), Expect = 0.013
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = -2
Query: 548 PTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAV 369
PTT T+ + ++ + ++ A R ++PS G +PT+ +A S SS A
Sbjct: 160 PTTAASTTTASHRTRPSSSEIDSKSTTASRRTSAVPSSTGASPTKPSARVSSTTSSTTAA 219
Query: 368 GRTPAKSGRAQSANSMTTPSSTP 300
R PA S S T S TP
Sbjct: 220 ARKPASSSTVSPRTSTTGVSRTP 242
>UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4;
Euteleostomi|Rep: L-lactate dehydrogenase - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 42.3 bits (95), Expect = 0.017
Identities = 43/180 (23%), Positives = 75/180 (41%), Gaps = 1/180 (0%)
Frame = +1
Query: 271 LHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGME 450
L L+D+ M L+G +M+L +L L + + + + ++EG
Sbjct: 49 LALVDV--MEDRLKGELMDLQHGSLFLKTSKIVADKDYSVTANSRLVVVTAGVRQQEGES 106
Query: 451 RKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM-T 627
R +L+ NV +FK + K + + ++VV NP + + K + +PK T
Sbjct: 107 RLNLVQRNVNVFKSIIPQIIKYS-PNCTLIVVSNPVDVLTYVTWKLS-GLPKHRVIGSGT 164
Query: 628 RLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDD 807
LD R + +A ++G+ ++ G H T P S A QK +I DD
Sbjct: 165 NLDSARFRYLMAERLGIHASSFNGWVL-GEHGDTSVPVWSGANVAGVNLQKLNPDIGTDD 223
>UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1;
Burkholderia ambifaria MC40-6|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 543
Score = 42.3 bits (95), Expect = 0.017
Identities = 37/184 (20%), Positives = 82/184 (44%), Gaps = 2/184 (1%)
Frame = -1
Query: 720 MVSPDDYSLNIFNWYSNFSSKLGLSPVLIKTSHGSEIFFWNRWSIFRTY*SICIGW--VA 547
+V+P L+ + + +L V+++ H E+ R R + + +G VA
Sbjct: 356 VVAPHGELLDRCDRLARLRGELRQRAVVVEAQHCGEVLL--RQIRCRLHGDVRVGVRRVA 413
Query: 546 NNKDLHIFTSRFVQSLALLFEDAHISSKKILPLHTFLSGHXXXXXXXXXXXXXXFRICCR 367
+++ LH+ FVQ AL ED + +++L H + RI
Sbjct: 414 DDQHLHVAARDFVQRGALDREDLGVRRQQVLAFHALRARTCADQQSDVCILECHLRIVGD 473
Query: 366 KNPSQKWQSTVGQLHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTS 187
+ ++ + + +LH + F R ++++++DRL+ ++ + R+ ++ VC+L+
Sbjct: 474 HDAREQRERAIVELHHDAFDGGLGLREVEQLQDDRLVLAEQVAVRDAEQQGVCDLTCGAG 533
Query: 186 YNNS 175
N+
Sbjct: 534 DGNA 537
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 41.5 bits (93), Expect = 0.030
Identities = 42/161 (26%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Frame = +1
Query: 277 LLDIAPMMGVLEGVVMELADCALPLLAGV-LPTANPEEAFKDVAAAFLVGAMPRKEGME- 450
L D+ P M G ++L A GV + AN + + + + + G
Sbjct: 38 LFDVVPNMPA--GKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95
Query: 451 ----RKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFT 618
RKDLL NV+I +E G A+ K V+ + NP + + + A +P
Sbjct: 96 QEWSRKDLLPVNVKILREVGAAI-KQFCPHAFVINITNPLDV-MVAALREAAGLPAARVC 153
Query: 619 AMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 738
M LD R + LA ++GV +DV+ +++ G H P
Sbjct: 154 GMAGVLDSARFRRLLADRLGVSPRDVQAMVL-GVHGDNMVP 193
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 40.7 bits (91), Expect = 0.052
Identities = 45/177 (25%), Positives = 73/177 (41%)
Frame = +1
Query: 277 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 456
++D+ P +++ V++LAD A + + + EEA + GA R EG R
Sbjct: 34 IVDVNP--DIVQAQVLDLADAA-SISHTPIRAGSAEEAGQADIVVITAGAKQR-EGEPRT 89
Query: 457 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 636
L+ N R+ + + + R D +LVV NP + I + P + + T LD
Sbjct: 90 KLIERNFRVLQSIIGGM-QPIRPDAVILVVANPVDILTHIAKTLSGLPPNQVIGSGTYLD 148
Query: 637 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDD 807
R + L V + V ++ G H +Q A A +I G S E D
Sbjct: 149 TTRLRVHLGDVFDVNPQSVHAFVL-GEHGDSQM-IAWEAASIGGQPLTSFPEFAKLD 203
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 39.5 bits (88), Expect = 0.12
Identities = 36/139 (25%), Positives = 55/139 (39%)
Frame = +1
Query: 340 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 519
A P+ G D L +K G R DLL N IF+E + +AA
Sbjct: 48 AAPVSHGTRVWHGGHSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAA 107
Query: 520 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 699
D +LV NP + + ++ AP P + T LD R + +A GV
Sbjct: 108 -PDAVLLVTSNPVDLLTDLATQLAPGQPV--IGSGTVLDSARFRHLMAQHAGVDGTHAHG 164
Query: 700 VIIWGNHSSTQFPDASNAV 756
++ G H ++ S+A+
Sbjct: 165 YVL-GEHGDSEVLAWSSAM 182
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 39.1 bits (87), Expect = 0.16
Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 1/158 (0%)
Frame = +1
Query: 322 MELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQ 501
M++AD + V+ KD + +PR G R D+L +V ++
Sbjct: 47 MDIADSVSFFNSSVIVRCGDYSDCKDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVS 106
Query: 502 ALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKEN-FTAMTRLDQNRAQSQLAAKIGV 678
L+K K + ++ + NPA+ A K A +PK F+ T LD R + +A +
Sbjct: 107 NLNKIEIKGI-IITITNPADIIADFVRK-ATGLPKNRVFSTGTSLDTARMRRTVADLCNI 164
Query: 679 PVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSE 792
+ V + G H + SN + I G K + E
Sbjct: 165 APQSVIGFAM-GEHGDSSMVPFSN-LTIFGKNYKHLKE 200
>UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium
salinarum|Rep: Vng6368h - Halobacterium salinarium
(Halobacterium halobium)
Length = 141
Score = 37.5 bits (83), Expect = 0.48
Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Frame = -2
Query: 548 PTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAA-TSLKASSGFA 372
PT F RA++ + T + +RS S P+ P+ + A AS+
Sbjct: 3 PTMPRFPCSRASMMERSRKLSSSTTYSRKRSTASRPTPATTQPSTSSIAWKKTPASTSTH 62
Query: 371 VGRTPAKSGRAQSANSMTTPSSTPIIGAISR 279
TP++ GR SAN +PSSTP + I +
Sbjct: 63 SPPTPSRQGRPSSANRNRSPSSTPALSRICK 93
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 37.5 bits (83), Expect = 0.48
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Frame = +1
Query: 394 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 573
KD + + K G R D++ N++IF+ + K + + +LVV NP +
Sbjct: 72 KDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSI-LLVVSNPVDILTY 130
Query: 574 ICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQ 732
I K + PKE T LD +R + L+ + ++V II G H ++
Sbjct: 131 ITYKLS-GFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNVHTYII-GEHGDSE 182
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 36.3 bits (80), Expect = 1.1
Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 3/127 (2%)
Frame = +1
Query: 427 MPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICS---KYAPS 597
+PRK GM+R+DL+ N + E A + + + NP N I + K +
Sbjct: 105 LPRKPGMKREDLVDVNASVACEVAFAASEVC-PGAMLAFITNPINVIVPIVATILKAKGT 163
Query: 598 IPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQ 777
+T LD RAQ+ +A + V + V +I G+ T P S G
Sbjct: 164 YDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCDPPFKGTD 223
Query: 778 KSVSEII 798
K +I
Sbjct: 224 KEREALI 230
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 36.3 bits (80), Expect = 1.1
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 1/121 (0%)
Frame = +1
Query: 373 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 552
A E KD + K G R DL+ N IFK + K + K + +LVV N
Sbjct: 64 AGDYEDTKDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSI-LLVVSN 122
Query: 553 PANTNALICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 729
P + + K + P+E T LD +R + L + V++V I+ G H +
Sbjct: 123 PVDILTYVTYKLS-GFPQERVIGSGTVLDTSRFRYLLGEHFKIDVRNVHTYIL-GEHGDS 180
Query: 730 Q 732
+
Sbjct: 181 E 181
>UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep:
Predicted protein - Gossypium hirsutum (Upland cotton)
(Gossypium mexicanum)
Length = 253
Score = 35.9 bits (79), Expect = 1.5
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Frame = +1
Query: 277 LLDIAPMMGVLEGV--VMELADCA-LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGM 447
L+++A + GVL G+ VM+ ADC L L GVL NP ++ +A ++ RK G
Sbjct: 173 LVEVA-LKGVLAGLERVMKAADCVRLKALKGVLDVLNPSQSLDFLAGICMLQIQIRKWGQ 231
Query: 448 ERKDLLAANVRIFKE 492
R + +N I E
Sbjct: 232 NRDNQKGSNPIILGE 246
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 35.9 bits (79), Expect = 1.5
Identities = 28/126 (22%), Positives = 47/126 (37%)
Frame = +1
Query: 361 VLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVL 540
++ AN + PR+ GM R DLL AN ++ + + ++ V V+
Sbjct: 55 IVRVANEPSDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVM 114
Query: 541 VVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNH 720
V NP + K + P + LD R S + K+G + ++ G H
Sbjct: 115 -VSNPLDAMVYTAIKESGLSPLQVLGMAGILDSARMASFIFEKLGYGSDQIVASVM-GGH 172
Query: 721 SSTQFP 738
P
Sbjct: 173 GDDMVP 178
>UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep:
Malate dehydrogenase - Phenylobacterium immobile
Length = 25
Score = 35.9 bits (79), Expect = 1.5
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +1
Query: 169 PIRVVVTGAAGQIAYSLLYQIA 234
PIRV VTGAAG I Y LL++IA
Sbjct: 4 PIRVAVTGAAGNIGYHLLFRIA 25
>UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 199
Score = 35.5 bits (78), Expect = 1.9
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +1
Query: 178 VVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
+V G G + IA G QP+ LH+LDI P VL G V+ + D
Sbjct: 101 LVAVGMGGGTSSGEAPMIARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 153
Score = 33.5 bits (73), Expect = 7.9
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +1
Query: 229 IASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 336
IA G QP+ LH+LDI P VL G V+ + D
Sbjct: 13 IARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 48
>UniRef50_O97299 Cluster: Putative uncharacterized protein
MAL3P7.37; n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein MAL3P7.37 - Plasmodium
falciparum (isolate 3D7)
Length = 1542
Score = 35.5 bits (78), Expect = 1.9
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = -1
Query: 324 HDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNSYRFSHFD 154
HDN + Y H +N K E +R+ + K ++N +K V +T NN+Y + D
Sbjct: 204 HDNNYNYFHVGKNEKMKERERINKKKKIGKKNNRRKHVLR-KNNTDGNNNYNDDNND 259
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 35.5 bits (78), Expect = 1.9
Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 1/186 (0%)
Frame = +1
Query: 310 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFK 489
EG V +L D A A + T +A +D + +PRK G R DL+ N +I +
Sbjct: 44 EGDVKDLEDVAAFTNATNIHTGEYADA-RDADIVVITAGVPRKPGESRLDLINRNTKILE 102
Query: 490 EQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM-TRLDQNRAQSQLAA 666
+ + A+ + ++ NP + + + + P+ T LD R + LA
Sbjct: 103 SIVKPV-VASGFNGCFVISSNPVDILTSMTQRLS-GFPRHRVIGTGTSLDTARLRVALAQ 160
Query: 667 KIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQK 846
K+ V V ++ G H + + + + I K+V+ + DD + K V+
Sbjct: 161 KLNVATTAVDAAVL-GEHGDSSIVN-FDEIMINAQPLKTVTTV--DDQF-KAEIEQAVRG 215
Query: 847 RGAAVI 864
+G +I
Sbjct: 216 KGGQII 221
>UniRef50_Q9BYR4 Cluster: Keratin-associated protein 4-3; n=53;
Mammalia|Rep: Keratin-associated protein 4-3 - Homo
sapiens (Human)
Length = 195
Score = 35.5 bits (78), Expect = 1.9
Identities = 49/171 (28%), Positives = 59/171 (34%), Gaps = 8/171 (4%)
Frame = +3
Query: 177 SCCNW-CCRTNCILTS--LSNCVWSSFWTSTTCLPPPS*YCAYDGCT*RCCHGVGRLCSA 347
SCC CCRT C S +S+C S S+ C P C C CC + C
Sbjct: 28 SCCQTTCCRTTCCRPSCCISSCCRPSCCISSCCKPS---CCRTTCCRPSCC--ISSCCRP 82
Query: 348 TFGWGSSYSKS*RSFQRXXXXFPSWCYAQKGRYGEEGSSCC--*CAHLQRARPGFGQSGS 521
+ S S R PS C + R SSCC C RP S
Sbjct: 83 SCCISSCCKP---SCCRTTCCRPSCCISSCCRPSCCISSCCKPSCCQTTCCRPSCCISSC 139
Query: 522 *R--CEGPCCWQPSQYKCSNMF*ICSIYSKR-KFHCHDSS*SKQGSVPTCC 665
R C P C +P+ S C + S R F C + P CC
Sbjct: 140 YRPQCCQPSCCRPACCISSCCHPSCCVSSCRCPFSCPTTCCRTTCFHPICC 190
>UniRef50_Q827S2 Cluster: Putative aminodeoxychorismate lyase; n=2;
Streptomyces|Rep: Putative aminodeoxychorismate lyase -
Streptomyces avermitilis
Length = 605
Score = 35.1 bits (77), Expect = 2.6
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 298 MGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLV-GAMPRKEGMERKDLLAAN 474
+GV +G +A+ L G+ AN ++ KD FL P +GM+ KD+L
Sbjct: 383 LGVKKGTTKGVAEKEWSTL-GLPDWANTDKDIKDPLEGFLYPSTYPVSKGMKPKDVLKEM 441
Query: 475 VRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNR 645
V + K++ AL A+ K L + NP + + K +F + R+ NR
Sbjct: 442 VNLAKDKYAALGIQAK--AKDLNLKNPLQVLTVASLVQSEGNSKNDFEKVARVVYNR 496
>UniRef50_Q2RQ78 Cluster: Putative uncharacterized protein; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: Putative
uncharacterized protein - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 696
Score = 35.1 bits (77), Expect = 2.6
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = -2
Query: 680 GTPILAASWD*ALF*SRRVMAVKFSFGIDGAYLEHIRAFVLAGLPTTRTFTSLRAALSKA 501
GTP++A W AL RR +FG+D A + A+V L R RAA +
Sbjct: 605 GTPVVA--WQGALMRDRRAAFWCAAFGLDEAVVRTAEAYVRQALAFGRDRAKRRAAAERL 662
Query: 500 WPCSLKMRTLAARRSFLSIPSFLGIAP 420
C+ R R ++ SFL P
Sbjct: 663 --CAAAPRLFGDPRGLSALVSFLADGP 687
>UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 571
Score = 35.1 bits (77), Expect = 2.6
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +3
Query: 300 GCT*RCCHGVGRLCSATFGWGSSY 371
GC CC GVG + S T GWGSSY
Sbjct: 539 GCGGGCCGGVGFVESPTCGWGSSY 562
>UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P1.39;
n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein MAL13P1.39 - Plasmodium
falciparum (isolate 3D7)
Length = 6088
Score = 35.1 bits (77), Expect = 2.6
Identities = 21/56 (37%), Positives = 29/56 (51%)
Frame = -1
Query: 327 LHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNSYRFSH 160
L DN FK + R NIKK+ E+R SKN +N KK + N+ Y + S+
Sbjct: 1044 LQDNYFKKLYDR-NIKKMMEERENASKNIFAKNKKKKIILNILKKVYYRYEHNLSN 1098
>UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidase;
n=2; Neurospora crassa|Rep: Related to glucan 1,
4-alpha-glucosidase - Neurospora crassa
Length = 701
Score = 35.1 bits (77), Expect = 2.6
Identities = 29/93 (31%), Positives = 43/93 (46%)
Frame = +1
Query: 325 ELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQA 504
EL +C P++ TA PE + AAA A RKE M +LA V + + +A
Sbjct: 383 ELEECGSPVVPW---TARPELSNAVAAAAAAAAAAERKEAMVGVPVLAVPVPPSRARTRA 439
Query: 505 LDKAARKDVKVLVVGNPANTNALICSKYAPSIP 603
+A + V+ +V GN A A + P +P
Sbjct: 440 QTQA--QSVQTVVTGNKAAAVAAAVALQIPQLP 470
>UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein
family 5 precursor; n=1; Roseiflexus castenholzii DSM
13941|Rep: Extracellular solute-binding protein family 5
precursor - Roseiflexus castenholzii DSM 13941
Length = 564
Score = 34.7 bits (76), Expect = 3.4
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 15/111 (13%)
Frame = +1
Query: 301 GVLEGVVMELADCALPLLAGVLPTANP--EEAFK---DVAAAFL--VGAMPRKEGMERKD 459
G++E V + + A L+ V P P E+ ++ + AA L G +P +G+ KD
Sbjct: 344 GIIESVYFNMVEPAYGPLSRVFPEYEPALEQMYEYNPEKAAQLLEEAGWLPGPDGVRVKD 403
Query: 460 LLAANVRIFKEQG--------QALDKAARKDVKVLVVGNPANTNALICSKY 588
V I + +G QA +A D KVL P+NT A+ KY
Sbjct: 404 GRRLEVTIVENKGWNDWVYVLQANLQAIGFDAKVLTTQGPSNTEAIASGKY 454
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 34.7 bits (76), Expect = 3.4
Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 3/122 (2%)
Frame = +1
Query: 382 EEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPAN 561
E A + MPR GM+R L+AAN + + A+ A+ + + + NP N
Sbjct: 85 ESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPR-AHLAFITNPVN 143
Query: 562 TNALICSKYA---PSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQ 732
++ + +T LD R++ + + + DV +I G+ T
Sbjct: 144 MIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITI 203
Query: 733 FP 738
P
Sbjct: 204 LP 205
>UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococcus
geothermalis DSM 11300|Rep: Peptidase M23B precursor -
Deinococcus geothermalis (strain DSM 11300)
Length = 330
Score = 34.3 bits (75), Expect = 4.5
Identities = 25/59 (42%), Positives = 33/59 (55%)
Frame = -2
Query: 479 RTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSST 303
RT+AAR +PS G+ P RK+AA+S A RTPA + RA S + PS+T
Sbjct: 157 RTVAAR-----LPSSEGVTPDRKSAASS-------AARRTPAATVRAASIRVTSAPSAT 203
>UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Cell
wall surface anchor family protein; n=3; Dictyostelium
discoideum|Rep: Similar to Streptococcus pneumoniae. Cell
wall surface anchor family protein - Dictyostelium
discoideum (Slime mold)
Length = 1806
Score = 34.3 bits (75), Expect = 4.5
Identities = 23/61 (37%), Positives = 30/61 (49%)
Frame = -2
Query: 419 TRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTA 240
T AA T+ ++S F TP+ S S +S+TT ST + GA S TG G T
Sbjct: 1220 TTTAATTATPSTSLFGSTTTPSTSS---STSSLTTTPSTGLFGASSSTTPSTGLFGSATT 1276
Query: 239 P 237
P
Sbjct: 1277 P 1277
>UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin
associated protein 9.2; n=1; Homo sapiens|Rep:
PREDICTED: similar to keratin associated protein 9.2 -
Homo sapiens
Length = 301
Score = 33.9 bits (74), Expect = 5.9
Identities = 17/54 (31%), Positives = 20/54 (37%), Gaps = 2/54 (3%)
Frame = +3
Query: 168 TYKSCCNWCCRTNCILTSLSNCVWSSFWTSTTCLPPP--S*YCAYDGCT*RCCH 323
T CC+ CC+ C T+ T TTC P C C CCH
Sbjct: 75 TMTHCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPSCCVPSCCQPCCH 128
>UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep:
LOC568298 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 258
Score = 33.9 bits (74), Expect = 5.9
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Frame = -2
Query: 548 PTTRT-FTSLRAALSKAWPCSLKMRTLAARRSFL--SIPSFLGIAPTRKAAATSLKASSG 378
PTT+T F S S +P S + LAA + F + + G +P A S A +
Sbjct: 25 PTTQTTFGSSTFTTSSNFPASTP-QALAAPKPFAFGAAGASSGASPFTFGTAASTSAPA- 82
Query: 377 FAVGRTPAKSGRAQ--SANSMTTPSSTPIIGAISR 279
F PA G + S + TTPS+TP+ GA ++
Sbjct: 83 FGTNSQPAFGGVSSGFSFGNTTTPSATPVFGATTQ 117
>UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 621
Score = 33.9 bits (74), Expect = 5.9
Identities = 32/117 (27%), Positives = 48/117 (41%)
Frame = -2
Query: 530 TSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAK 351
TS+ W + K L + +S P+ P A +++ ASS TP
Sbjct: 469 TSVVETKKMEWGPADKKSVLPVETTVVSPPTTTTTTPV--APTSNVAASSSSTATATPTT 526
Query: 350 SGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI**RSEYAICPAAPVTT 180
+ Q+A S PS+ S+ PK +P + +S+ A PAAPVTT
Sbjct: 527 TTTTQTAASTNAPSNKKSTTQSSQ---------PKKSPSKVEDKSKTAPTPAAPVTT 574
>UniRef50_Q1JTH9 Cluster: Hyothetical protein; n=4; root|Rep:
Hyothetical protein - Toxoplasma gondii RH
Length = 1821
Score = 33.9 bits (74), Expect = 5.9
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Frame = +3
Query: 75 LFHSSSESAKXXXXXXXXXXXXXXXXYQNG*TYKSC----CNWCCRTNCILTSLSNCVWS 242
LF S S S+ +G ++ SC C+ C ++C +S S C +S
Sbjct: 558 LFSSCSSSSWSGCSFSSCSSSSCSSSSCSGCSFSSCSSSSCSGCSSSSCSSSSWSGCSFS 617
Query: 243 SFWTSTTCLPPPS*YCAYDGCT*RCCHGVGRLCSATFGW-GSSYS 374
S +S++C C++ C+ C G ++ W G S+S
Sbjct: 618 S-CSSSSCSG-----CSFSSCSSSSCSGCSSSSCSSSSWSGCSFS 656
>UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34;
Proteobacteria|Rep: Ornithine cyclodeaminase 1 -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 329
Score = 33.9 bits (74), Expect = 5.9
Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 5/109 (4%)
Frame = -2
Query: 599 IDGAYLEHIR---AFVLAGLPTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLG 429
+D YL +R A +A +R +S+ A L++ LA R +
Sbjct: 106 LDNGYLTDVRTAAAGAVAARRLSREDSSVAAVFGAGMQARLQLEALALVRPIREARIWAR 165
Query: 428 IAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSM--TTPSSTPIIGA 288
A +AAA +L GFAV A+ + TTPS TP++ A
Sbjct: 166 DAAKAEAAAIALGGKLGFAVKAETDPRAAITGADIIVTTTPSETPVLKA 214
>UniRef50_UPI00006CFE65 Cluster: hypothetical protein
TTHERM_00691510; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00691510 - Tetrahymena
thermophila SB210
Length = 1176
Score = 33.5 bits (73), Expect = 7.9
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Frame = -1
Query: 345 QSTVGQLHDNTFKYTHHRRNIKKVEEDRLLRSKN-CSRRNLIKK*VCNLSGSTSYNNSYR 169
Q ++ Q++ + KY H+ N + EED + SKN S N IK L+ ++ N YR
Sbjct: 66 QQSIQQINQSYNKYVLHQNNQQNDEEDNMNFSKNILSLHNTIKTNQSQLANQSAIQN-YR 124
Query: 168 FS 163
+S
Sbjct: 125 YS 126
>UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep:
Beta-lactamase - Vibrio angustum S14
Length = 318
Score = 33.5 bits (73), Expect = 7.9
Identities = 18/44 (40%), Positives = 26/44 (59%)
Frame = +1
Query: 607 ENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 738
EN T + ++ A+ QL A+IGV V D K ++G HS +FP
Sbjct: 54 ENITVNSAIEH--AEKQLGARIGVSVFDGKGKQLFGYHSDQRFP 95
>UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1;
Rhodococcus sp. RHA1|Rep: Putative uncharacterized
protein - Rhodococcus sp. (strain RHA1)
Length = 362
Score = 33.5 bits (73), Expect = 7.9
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = -2
Query: 836 VVTNAPFKYASSLIISETDF*APPTIATAFEASGNWVDEWFPQMITLLT 690
VV P +S+ +I + ++ AP IA + E +W+ +FPQ+I LT
Sbjct: 126 VVIKVPRNVSSNALI-DAEWAAPTEIAASAEGGNDWLRAYFPQLIDHLT 173
>UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3;
Sordariomycetes|Rep: Related to DOS1 protein -
Neurospora crassa
Length = 452
Score = 33.5 bits (73), Expect = 7.9
Identities = 18/59 (30%), Positives = 30/59 (50%)
Frame = -2
Query: 464 RRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGA 288
R + +S L IA T+ AA+ + ASSG + + S + S + TTP++ + A
Sbjct: 90 RTTLISRTRALSIATTQAAASAAAAASSGVTAASSSSSSSSSASKDEQTTPTTVKDLSA 148
>UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1;
Methanosarcina mazei|Rep: Putative uncharacterized
protein - Methanosarcina mazei (Methanosarcina frisia)
Length = 324
Score = 33.5 bits (73), Expect = 7.9
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 7/108 (6%)
Frame = +1
Query: 142 LYGNIKMAEPIRVVVTGAAGQIAYSLLYQIAS--GAVFGPQQPV----FLHLLDIAPMMG 303
L GN+K+ P+ V+ + A + + L +I + AV +PV F +L P+
Sbjct: 215 LLGNLKLLIPLGVIASALASLLYFRGLARIKAQTAAVLSLIEPVSSICFCCILLGEPLQS 274
Query: 304 -VLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 444
+ G ++ LA AL + + PE+ F+DV A F MP + G
Sbjct: 275 NTVGGCLLILAGAALIGSSTSIQQGIPEKYFRDVWARFFQPYMPLRPG 322
>UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila
melanogaster|Rep: Protein trithorax - Drosophila
melanogaster (Fruit fly)
Length = 3726
Score = 33.5 bits (73), Expect = 7.9
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Frame = -2
Query: 518 AALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRA 339
AA KA S RT +A S S G +P + A+S ASSG + G++ AKS A
Sbjct: 157 AASGKA--LSKSSRTFSASTSVTSSGRSSGSSPDGNSGASSDGASSGISCGKSTAKSTEA 214
Query: 338 QSAN-SMTTPSST 303
S + TT + T
Sbjct: 215 SSGKLAKTTGAGT 227
>UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47;
Craniata|Rep: Homeobox protein Hox-D13 - Homo sapiens
(Human)
Length = 335
Score = 33.5 bits (73), Expect = 7.9
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Frame = -2
Query: 461 RSFLSIPSFLGI-----APTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTP 300
R FLS P F G A AAA + A+SGFA T ++G + S++S ++ P
Sbjct: 33 RGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARP 91
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 853,387,031
Number of Sequences: 1657284
Number of extensions: 17418678
Number of successful extensions: 54773
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 51809
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54656
length of database: 575,637,011
effective HSP length: 101
effective length of database: 408,251,327
effective search space used: 85324527343
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -