Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_K07
(779 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC110833-1|AAI10834.1| 952|Homo sapiens POLR1B protein protein. 175 1e-43
AK128044-1|BAC87247.1| 1135|Homo sapiens protein ( Homo sapiens ... 175 1e-43
AK001678-1|BAA91831.1| 336|Homo sapiens protein ( Homo sapiens ... 175 1e-43
AC012442-2|AAX81999.1| 1135|Homo sapiens unknown protein. 175 1e-43
AK022533-1|BAB14082.1| 1079|Homo sapiens protein ( Homo sapiens ... 106 8e-23
BC046238-1|AAH46238.1| 1133|Homo sapiens polymerase (RNA) III (D... 54 6e-07
AY092084-1|AAM18214.1| 1133|Homo sapiens RNA polymerase III subu... 54 6e-07
X63563-1|CAA45124.1| 1174|Homo sapiens RNA polymerase II 140 kDa... 49 2e-05
BC023503-1|AAH23503.2| 1174|Homo sapiens polymerase (RNA) II (DN... 49 2e-05
>BC110833-1|AAI10834.1| 952|Homo sapiens POLR1B protein protein.
Length = 952
Score = 175 bits (427), Expect = 1e-43
Identities = 87/215 (40%), Positives = 131/215 (60%), Gaps = 1/215 (0%)
Frame = +2
Query: 137 KKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFE 316
+ L PSL + + P Y P + LQ L H++SFNY + +GL A+ + P EF
Sbjct: 8 RNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQAIPPFEFA 67
Query: 317 LPSGEKVKVTIDEAAFAKPNVPMDTVGVKSQVVLPTECRQRAATYKGELKIRVTLCIDGR 496
E++ TI +A + P VP T+ K V P ECR R +TY+G+L + ++G
Sbjct: 68 FKD-ERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVNGI 125
Query: 497 SV-TIERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLXRMLLVT 673
S I++ LGY+PIM+KSK+C+L +L P+ LIE +E A+E GGYF+I G E++ RML++
Sbjct: 126 SKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMP 185
Query: 674 RRNYPVAIKRSGWKMRGNLFSXYGVLVRCVTSDQT 778
RRN+P+A+ R WK RG ++ YGV + CV + +
Sbjct: 186 RRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHS 220
>AK128044-1|BAC87247.1| 1135|Homo sapiens protein ( Homo sapiens
cDNA FLJ46164 fis, clone TESTI4002799, highly similar
to DNA-directed RNA polymerase I 135 kDa polypeptide (EC
2.7.7.6). ).
Length = 1135
Score = 175 bits (427), Expect = 1e-43
Identities = 87/215 (40%), Positives = 131/215 (60%), Gaps = 1/215 (0%)
Frame = +2
Query: 137 KKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFE 316
+ L PSL + + P Y P + LQ L H++SFNY + +GL A+ + P EF
Sbjct: 8 RNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQAIPPFEFA 67
Query: 317 LPSGEKVKVTIDEAAFAKPNVPMDTVGVKSQVVLPTECRQRAATYKGELKIRVTLCIDGR 496
E++ TI +A + P VP T+ K V P ECR R +TY+G+L + ++G
Sbjct: 68 FKD-ERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVNGI 125
Query: 497 SV-TIERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLXRMLLVT 673
S I++ LGY+PIM+KSK+C+L +L P+ LIE +E A+E GGYF+I G E++ RML++
Sbjct: 126 SKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMP 185
Query: 674 RRNYPVAIKRSGWKMRGNLFSXYGVLVRCVTSDQT 778
RRN+P+A+ R WK RG ++ YGV + CV + +
Sbjct: 186 RRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHS 220
>AK001678-1|BAA91831.1| 336|Homo sapiens protein ( Homo sapiens
cDNA FLJ10816 fis, clone NT2RP4000997, highly similar to
DNA-DIRECTED RNA POLYMERASE I 135 KD POLYPEPTIDE (EC
2.7.7.6). ).
Length = 336
Score = 175 bits (427), Expect = 1e-43
Identities = 87/215 (40%), Positives = 131/215 (60%), Gaps = 1/215 (0%)
Frame = +2
Query: 137 KKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFE 316
+ L PSL + + P Y P + LQ L H++SFNY + +GL A+ + P EF
Sbjct: 8 RNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQAIPPFEFA 67
Query: 317 LPSGEKVKVTIDEAAFAKPNVPMDTVGVKSQVVLPTECRQRAATYKGELKIRVTLCIDGR 496
E++ TI +A + P VP T+ K V P ECR R +TY+G+L + ++G
Sbjct: 68 FKD-ERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVNGI 125
Query: 497 SV-TIERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLXRMLLVT 673
S I++ LGY+PIM+KSK+C+L +L P+ LIE +E A+E GGYF+I G E++ RML++
Sbjct: 126 SKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMP 185
Query: 674 RRNYPVAIKRSGWKMRGNLFSXYGVLVRCVTSDQT 778
RRN+P+A+ R WK RG ++ YGV + CV + +
Sbjct: 186 RRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHS 220
>AC012442-2|AAX81999.1| 1135|Homo sapiens unknown protein.
Length = 1135
Score = 175 bits (427), Expect = 1e-43
Identities = 87/215 (40%), Positives = 131/215 (60%), Gaps = 1/215 (0%)
Frame = +2
Query: 137 KKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFE 316
+ L PSL + + P Y P + LQ L H++SFNY + +GL A+ + P EF
Sbjct: 8 RNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQAIPPFEFA 67
Query: 317 LPSGEKVKVTIDEAAFAKPNVPMDTVGVKSQVVLPTECRQRAATYKGELKIRVTLCIDGR 496
E++ TI +A + P VP T+ K V P ECR R +TY+G+L + ++G
Sbjct: 68 FKD-ERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVNGI 125
Query: 497 SV-TIERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLXRMLLVT 673
S I++ LGY+PIM+KSK+C+L +L P+ LIE +E A+E GGYF+I G E++ RML++
Sbjct: 126 SKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMP 185
Query: 674 RRNYPVAIKRSGWKMRGNLFSXYGVLVRCVTSDQT 778
RRN+P+A+ R WK RG ++ YGV + CV + +
Sbjct: 186 RRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHS 220
>AK022533-1|BAB14082.1| 1079|Homo sapiens protein ( Homo sapiens
cDNA FLJ12471 fis, clone NT2RM1000894, highly similar to
DNA-DIRECTED RNA POLYMERASE I 135 KD POLYPEPTIDE (EC
2.7.7.6). ).
Length = 1079
Score = 106 bits (255), Expect = 8e-23
Identities = 45/91 (49%), Positives = 68/91 (74%)
Frame = +2
Query: 506 IERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLXRMLLVTRRNY 685
I++ LGY+PIM+KSK+C+L +L P+ LIE +E A+E GGYF+I G E++ RML++ RRN+
Sbjct: 74 IKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNF 133
Query: 686 PVAIKRSGWKMRGNLFSXYGVLVRCVTSDQT 778
P+A+ R WK RG ++ YGV + CV + +
Sbjct: 134 PIAMIRPKWKTRGPGYTQYGVSMHCVREEHS 164
Score = 40.3 bits (90), Expect = 0.008
Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Frame = +2
Query: 137 KKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAI-ADL 298
+ L PSL + + P Y P + LQ L H++SFNY + +GL A+ AD+
Sbjct: 8 RNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQADI 62
>BC046238-1|AAH46238.1| 1133|Homo sapiens polymerase (RNA) III (DNA
directed) polypeptide B protein.
Length = 1133
Score = 54.0 bits (124), Expect = 6e-07
Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Frame = +2
Query: 218 LQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFELPSGEKVKVTIDEAAFAKP-NVPMDTV 394
++ L HIDSFNY ++ +K + + EKV D + K N+ +
Sbjct: 36 VKGLVKQHIDSFNYFINVEIKKI----------MKANEKVTSDADPMWYLKYLNIYVGLP 85
Query: 395 GVK-----SQVVLPTECRQRAATYKGELKIRVTLCIDG-RSVTIERSLGYLPIMIKSKMC 556
V+ ++ V P ECR R TY + + + R + +G +PIM++S C
Sbjct: 86 DVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNC 145
Query: 557 HLADLSPEELIEKNEHADEWGGYFVIKGHERL 652
L +P E + NE + GGYF++KG E++
Sbjct: 146 VLTGKTPAEFAKLNECPLDPGGYFIVKGVEKV 177
>AY092084-1|AAM18214.1| 1133|Homo sapiens RNA polymerase III subunit
RPC2 protein.
Length = 1133
Score = 54.0 bits (124), Expect = 6e-07
Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Frame = +2
Query: 218 LQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFELPSGEKVKVTIDEAAFAKP-NVPMDTV 394
++ L HIDSFNY ++ +K + + EKV D + K N+ +
Sbjct: 36 VKGLVKQHIDSFNYFINVEIKKI----------MKANEKVTSDADPMWYLKYLNIYVGLP 85
Query: 395 GVK-----SQVVLPTECRQRAATYKGELKIRVTLCIDG-RSVTIERSLGYLPIMIKSKMC 556
V+ ++ V P ECR R TY + + + R + +G +PIM++S C
Sbjct: 86 DVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNC 145
Query: 557 HLADLSPEELIEKNEHADEWGGYFVIKGHERL 652
L +P E + NE + GGYF++KG E++
Sbjct: 146 VLTGKTPAEFAKLNECPLDPGGYFIVKGVEKV 177
>X63563-1|CAA45124.1| 1174|Homo sapiens RNA polymerase II 140 kDa
subunit protein.
Length = 1174
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Frame = +2
Query: 413 VLPTECRQRAATYKGELKIRVTLCI--DGRSVTIERS----LGYLPIMIKSKMCHLADLS 574
++P E R R TY L + +T + +G + +G +PIM++S C L L+
Sbjct: 108 MMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLT 167
Query: 575 PEELIEKNEHADEWGGYFVIKGHER--LXRMLLVTRRNYPVAIKRSGWKMRG 724
+L E NE + GGYF+I G E+ + + + T Y A K S + G
Sbjct: 168 DRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTG 219
>BC023503-1|AAH23503.2| 1174|Homo sapiens polymerase (RNA) II (DNA
directed) polypeptide B, 140kDa protein.
Length = 1174
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Frame = +2
Query: 413 VLPTECRQRAATYKGELKIRVTLCI--DGRSVTIERS----LGYLPIMIKSKMCHLADLS 574
++P E R R TY L + +T + +G + +G +PIM++S C L L+
Sbjct: 108 MMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLT 167
Query: 575 PEELIEKNEHADEWGGYFVIKGHER--LXRMLLVTRRNYPVAIKRSGWKMRG 724
+L E NE + GGYF+I G E+ + + + T Y A K S + G
Sbjct: 168 DRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTG 219
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,757,030
Number of Sequences: 237096
Number of extensions: 2237073
Number of successful extensions: 4040
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3891
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4028
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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