Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_F16
(733 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 152 1e-35
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 149 5e-35
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 141 1e-32
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 103 5e-21
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 84 3e-15
UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2; ... 84 4e-15
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 79 1e-13
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 77 3e-13
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 72 2e-11
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 71 4e-11
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 68 3e-10
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 66 8e-10
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 66 1e-09
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 66 1e-09
UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to Tyrosine-p... 65 1e-09
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 65 1e-09
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 65 1e-09
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 64 3e-09
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 64 3e-09
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 64 3e-09
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 64 4e-09
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 64 4e-09
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 63 6e-09
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 63 6e-09
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 63 6e-09
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 63 6e-09
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 63 6e-09
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 62 1e-08
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 62 1e-08
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 62 1e-08
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 62 1e-08
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 62 1e-08
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 62 2e-08
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;... 61 2e-08
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 61 2e-08
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 61 2e-08
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 61 2e-08
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 61 2e-08
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 61 2e-08
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 61 3e-08
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 60 5e-08
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 59 1e-07
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 59 1e-07
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 58 2e-07
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 58 2e-07
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 58 2e-07
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 58 2e-07
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 58 2e-07
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 58 2e-07
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 58 2e-07
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 58 2e-07
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 58 2e-07
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 58 3e-07
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 58 3e-07
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 57 4e-07
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 57 4e-07
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 57 4e-07
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 57 4e-07
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 57 5e-07
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 57 5e-07
UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s... 57 5e-07
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 56 7e-07
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 56 7e-07
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 56 7e-07
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 56 7e-07
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 56 9e-07
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 56 9e-07
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 56 1e-06
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 56 1e-06
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 56 1e-06
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 55 2e-06
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 55 2e-06
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 55 2e-06
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 55 2e-06
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 55 2e-06
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 54 3e-06
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 54 3e-06
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 54 3e-06
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 54 4e-06
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 54 4e-06
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 54 5e-06
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 54 5e-06
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 54 5e-06
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 53 6e-06
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 53 6e-06
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 53 6e-06
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 53 6e-06
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 53 6e-06
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 53 6e-06
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 53 8e-06
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 53 8e-06
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 53 8e-06
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 53 8e-06
UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella ve... 53 8e-06
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 52 1e-05
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 52 1e-05
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 52 1e-05
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 52 1e-05
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 52 1e-05
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 52 2e-05
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 52 2e-05
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 51 3e-05
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 51 3e-05
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 51 3e-05
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 51 3e-05
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 51 3e-05
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 51 3e-05
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 51 3e-05
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 51 3e-05
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 51 3e-05
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 51 3e-05
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ... 50 4e-05
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 50 4e-05
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 50 4e-05
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;... 50 4e-05
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 50 4e-05
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 50 4e-05
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 50 6e-05
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;... 50 6e-05
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 50 6e-05
UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 50 6e-05
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 50 6e-05
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 50 6e-05
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 50 8e-05
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 50 8e-05
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 50 8e-05
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 50 8e-05
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;... 49 1e-04
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 49 1e-04
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 49 1e-04
UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s... 49 1e-04
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 49 1e-04
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 49 1e-04
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 49 1e-04
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 49 1e-04
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 49 1e-04
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 49 1e-04
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 49 1e-04
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 49 1e-04
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 49 1e-04
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 48 2e-04
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 48 2e-04
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 48 2e-04
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 48 2e-04
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 48 3e-04
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 47 4e-04
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 47 4e-04
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 47 4e-04
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 47 4e-04
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 47 5e-04
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 47 5e-04
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 47 5e-04
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 47 5e-04
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 46 7e-04
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 46 7e-04
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 46 7e-04
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 46 7e-04
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 46 7e-04
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 46 0.001
UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:... 46 0.001
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 46 0.001
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 46 0.001
UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a... 46 0.001
UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain... 46 0.001
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 46 0.001
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 46 0.001
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 46 0.001
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 46 0.001
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 46 0.001
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 45 0.002
UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin... 45 0.002
UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:1... 45 0.002
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 45 0.002
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 45 0.002
UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91... 45 0.002
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 45 0.002
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 45 0.002
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 45 0.002
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 45 0.002
UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A... 45 0.002
UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|R... 45 0.002
UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ... 44 0.003
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 44 0.003
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 44 0.003
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 44 0.003
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 44 0.003
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 44 0.003
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 44 0.003
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 44 0.003
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 44 0.004
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 44 0.004
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 44 0.005
UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VII... 44 0.005
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 44 0.005
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 44 0.005
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 44 0.005
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 44 0.005
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 44 0.005
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 44 0.005
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 43 0.007
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 43 0.007
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 43 0.007
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 43 0.007
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 43 0.007
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 43 0.007
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 43 0.007
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 43 0.007
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 43 0.007
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 43 0.007
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 43 0.007
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 43 0.007
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 43 0.007
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 43 0.009
UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;... 43 0.009
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 43 0.009
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 43 0.009
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 43 0.009
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 42 0.012
UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol... 42 0.012
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 42 0.012
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 42 0.012
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 42 0.012
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 42 0.012
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 42 0.016
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 42 0.016
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 42 0.016
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.016
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 42 0.016
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 42 0.016
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 42 0.016
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 42 0.021
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 42 0.021
UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome s... 42 0.021
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 42 0.021
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 42 0.021
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 42 0.021
UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ... 42 0.021
UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;... 41 0.027
UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n... 41 0.027
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 41 0.027
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 41 0.027
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 41 0.027
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 41 0.027
UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;... 41 0.027
UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31... 41 0.027
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 41 0.027
UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell lin... 41 0.036
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 41 0.036
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 41 0.036
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 41 0.036
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 41 0.036
UniRef50_Q7Z4S9 Cluster: SH2 domain-containing protein 6; n=7; E... 41 0.036
UniRef50_A6ND14 Cluster: Uncharacterized protein SH2D6; n=10; Eu... 41 0.036
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 41 0.036
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 41 0.036
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 40 0.048
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 40 0.048
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 40 0.048
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 40 0.048
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 40 0.048
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 40 0.048
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 40 0.048
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.048
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 40 0.048
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 40 0.063
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 40 0.063
UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic... 40 0.063
UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep: Beta... 40 0.063
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 40 0.083
UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;... 40 0.083
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 40 0.083
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 40 0.083
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 40 0.083
UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;... 39 0.11
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 39 0.11
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 39 0.11
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 39 0.11
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 39 0.15
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 39 0.15
UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j... 39 0.15
UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ... 39 0.15
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 39 0.15
UniRef50_Q8JI35 Cluster: Blnk; n=2; Danio rerio|Rep: Blnk - Dani... 38 0.19
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 38 0.19
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 38 0.19
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 38 0.25
UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Re... 38 0.25
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 38 0.33
UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Re... 38 0.33
UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1... 38 0.33
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 38 0.33
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 37 0.44
UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37... 37 0.44
UniRef50_Q5C1M0 Cluster: SJCHGC08700 protein; n=1; Schistosoma j... 37 0.59
UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ... 37 0.59
UniRef50_Q6C233 Cluster: Yarrowia lipolytica chromosome F of str... 37 0.59
UniRef50_UPI0000F2148D Cluster: PREDICTED: similar to signal tra... 36 0.77
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 36 0.77
UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep: LO... 36 0.77
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 36 0.77
UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1... 36 1.0
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 36 1.0
UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor... 36 1.4
UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus... 36 1.4
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 36 1.4
UniRef50_Q4SNX7 Cluster: Chromosome 15 SCAF14542, whole genome s... 36 1.4
UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit... 36 1.4
UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.4
UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.4
UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.4
UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1... 36 1.4
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 35 1.8
UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R... 35 1.8
UniRef50_Q9XWW5 Cluster: Putative uncharacterized protein; n=2; ... 35 1.8
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.8
UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2... 35 1.8
UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote... 35 1.8
UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s... 35 2.4
UniRef50_Q06AL4 Cluster: Suppressor of cytokine signaling 1; n=5... 35 2.4
UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ... 35 2.4
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 35 2.4
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 34 3.1
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 34 3.1
UniRef50_Q6AM15 Cluster: Related to phosphate ABC transporter, p... 34 3.1
UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat... 34 4.1
UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat... 34 4.1
UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling... 34 4.1
UniRef50_Q9U3B5 Cluster: Putative uncharacterized protein; n=3; ... 34 4.1
UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;... 33 5.5
UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,... 33 5.5
UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2... 33 5.5
UniRef50_UPI0000DD7D9A Cluster: PREDICTED: hypothetical protein;... 33 7.2
UniRef50_UPI00005A9692 Cluster: PREDICTED: similar to cytochrome... 33 7.2
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 33 7.2
UniRef50_Q97J64 Cluster: Uncharacterized CBS domain-containing p... 33 7.2
UniRef50_Q14K90 Cluster: DivIVA protein; n=2; Corynebacterium|Re... 33 7.2
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 33 7.2
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 33 7.2
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_O01798 Cluster: Defective spermatogenesis protein 8; n=... 33 7.2
UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik... 33 9.5
UniRef50_Q1CZN9 Cluster: Kelch domain protein; n=1; Myxococcus x... 33 9.5
UniRef50_Q026N0 Cluster: Putative uncharacterized protein; n=3; ... 33 9.5
UniRef50_A5ZV83 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 33 9.5
UniRef50_Q0UXM4 Cluster: Putative uncharacterized protein; n=2; ... 33 9.5
UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi... 33 9.5
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 152 bits (368), Expect = 1e-35
Identities = 67/144 (46%), Positives = 102/144 (70%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFHG ++ KEAE +++KGKNGS+LVRES + PG+YVLSVR +V+HV+IR Q KY
Sbjct: 110 ERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKY 169
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDR 638
DVG GEQF+ L L++H+R PM+ET+G V+ L P + TR+ A I +V+ ++
Sbjct: 170 DVGGGEQFETLTDLVDHYRKNPMVETTGYVVHLKVPFNATRISASGIRNRVEVLEKETKS 229
Query: 639 QKMECNTGFDGEFQSLKLLEXRHV 710
++ GF+ EF++L+LL+ +H+
Sbjct: 230 RENSKKAGFEEEFEALQLLDNKHL 253
Score = 77.0 bits (181), Expect = 4e-13
Identities = 35/100 (35%), Positives = 62/100 (62%), Gaps = 2/100 (2%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFH +S EAE L++ G +G FL R S+++PG++ LSVR G V+H+ I+ + +
Sbjct: 4 RRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDFF 63
Query: 459 DVGSGEQFDDLVGLIEHFRS--YPMIETSGDVLRLLQPVS 572
D+ GE+F L L++H+ + E +G ++ L P++
Sbjct: 64 DLYGGEKFATLAELVQHYTEGRNQLKERNGQMIELKYPLN 103
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 149 bits (362), Expect = 5e-35
Identities = 74/160 (46%), Positives = 110/160 (68%), Gaps = 10/160 (6%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV----------RGRVSH 428
++WFHG +S KEAE L+ EKGK+GSFLVRESQ+HPG++VLSVR + +V+H
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTH 169
Query: 429 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQK 608
V+IR Q KYDVG GE+FD L L+EH++ PM+ET G VL+L QP++ TR+ A +I+ +
Sbjct: 170 VMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESR 229
Query: 609 VQEMQGIEDRQKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
V+E+ + + + GF EF++L+ E + +++ EG
Sbjct: 230 VRELSKLAETTD-KVKQGFWEEFETLQQQECKLLYSRKEG 268
Score = 83.4 bits (197), Expect = 5e-15
Identities = 37/100 (37%), Positives = 67/100 (67%), Gaps = 2/100 (2%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFH ++ EAE+L++ +G +GSFL R S+++PG++ LSVR G V+H+ I+ + Y
Sbjct: 4 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63
Query: 459 DVGSGEQFDDLVGLIEHFRSY--PMIETSGDVLRLLQPVS 572
D+ GE+F L L++++ + + E +GDV+ L P++
Sbjct: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 141 bits (342), Expect = 1e-32
Identities = 73/150 (48%), Positives = 100/150 (66%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFHG +S KEAE LI+E+GKNGSFLVRESQ+ PG++VLSVR +V+HV+IR Q KY
Sbjct: 109 ERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKY 168
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDR 638
DVG GE F L LI+H++ PM+ET G V+ L QP + TR+ A I+ +V+++
Sbjct: 169 DVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQL------ 222
Query: 639 QKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
GF EF+SL+ + R F+ EG
Sbjct: 223 ----VKGGFWEEFESLQ-QDSRDTFSRNEG 247
Score = 75.8 bits (178), Expect = 1e-12
Identities = 36/98 (36%), Positives = 61/98 (62%), Gaps = 1/98 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFH +S EAE L+ E+G +GSFL R S ++PG + LSVR V+H+ I+ + +
Sbjct: 4 RRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFF 63
Query: 459 DVGSGEQFDDLVGLIEHF-RSYPMIETSGDVLRLLQPV 569
D+ GE+F L L++++ + + E +G + L QP+
Sbjct: 64 DLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPL 101
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 103 bits (247), Expect = 5e-21
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 9/159 (5%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG---------RVSHV 431
++W+HG MS +AE+L+ KG+ +FLVRES + PG++VLSV RV+H+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHI 167
Query: 432 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKV 611
+ + +Y VG E FD L L+EHF+ + E SG + L QP TR+ A DI+ +V
Sbjct: 168 KVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRV 227
Query: 612 QEMQGIEDRQKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
E+ ++ + GF EF+SL+ E +++ +EG
Sbjct: 228 LELNKKQESED-TAKAGFWEEFESLQKQEVKNLHQRLEG 265
Score = 72.1 bits (169), Expect = 1e-11
Identities = 34/99 (34%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+WFH +S +AE+L+ +G +GSFL R S+ + G++ LSVRV +V+H+ I+ + YD
Sbjct: 3 RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62
Query: 462 VGSGEQFDDLVGLIEHFRSYPMI--ETSGDVLRLLQPVS 572
+ GE+F L L+E++ + + G ++ L P++
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLN 101
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 84.2 bits (199), Expect = 3e-15
Identities = 40/104 (38%), Positives = 67/104 (64%)
Frame = +3
Query: 417 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHD 596
RV ++I + KYDVG GE+FD L L+EH++ PM+ET G VL+L QP++ TR+ A +
Sbjct: 137 RVVFIIINKHDLKYDVGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAE 196
Query: 597 IDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
I+ +V+E+ + + + GF EF++L+ E + +++ EG
Sbjct: 197 IESRVRELSKLAEATD-KVKQGFWEEFETLQQQECKLLYSRKEG 239
Score = 63.7 bits (148), Expect = 4e-09
Identities = 26/61 (42%), Positives = 44/61 (72%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+WFH ++ EAE+L++ +G +GSFL R S+++PG++ LSVR G V+H+ I+ + YD
Sbjct: 5 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64
Query: 462 V 464
+
Sbjct: 65 L 65
>UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2;
Aedes aegypti|Rep: Protein tyrosine phosphatase n11 -
Aedes aegypti (Yellowfever mosquito)
Length = 511
Score = 83.8 bits (198), Expect = 4e-15
Identities = 43/99 (43%), Positives = 62/99 (62%)
Frame = +3
Query: 432 LIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKV 611
+IR NKYDVG G++F+ L LIEH++ PM+ET G V+ L QP + TR+ A ID +V
Sbjct: 1 MIRWHENKYDVGGGQKFNTLCDLIEHYKRNPMVETCGTVVHLRQPFNATRITAAGIDARV 60
Query: 612 QEMQGIEDRQKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
+++Q E+ GF EF+SL+ E R+ F+ EG
Sbjct: 61 EQLQR-ENGSHCYGKGGFWEEFESLQQQECRYTFSRREG 98
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 78.6 bits (185), Expect = 1e-13
Identities = 38/100 (38%), Positives = 61/100 (61%)
Frame = +3
Query: 429 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQK 608
V + + KYDVG GE+FD L L+EH++ PM+E SG V+ L QP + TR+ A +I+ +
Sbjct: 202 VALLQPDGKYDVGGGERFDTLTDLVEHYKKNPMVEKSGAVVHLKQPFNATRINAANIENR 261
Query: 609 VQEMQGIEDRQKMECNTGFDGEFQSLKLLEXRHVFTTIEG 728
V+E+ + D + + GF EF+ L+ E + ++ EG
Sbjct: 262 VRELNKMADHSE-KAKQGFWEEFEMLQQQECKLLYPRKEG 300
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/99 (34%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+WFH +S EAE L++ +G +GSFL R S+++PG++ LSVR V+H+ I+ + YD
Sbjct: 3 RWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYD 62
Query: 462 VGSGEQFDDLVGLIEHFRSYP--MIETSGDVLRLLQPVS 572
+ GE+F L++++ + E + +V+ L P++
Sbjct: 63 LYGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLN 101
Score = 64.9 bits (151), Expect = 2e-09
Identities = 27/42 (64%), Positives = 36/42 (85%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV 404
++W+HG ++ KEAE L+ EKGK GSFLVRESQ+ PG++VLSV
Sbjct: 108 ERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 77.4 bits (182), Expect = 3e-13
Identities = 58/163 (35%), Positives = 81/163 (49%), Gaps = 6/163 (3%)
Frame = +3
Query: 207 VLAVPAAGAIVSTVLKELSK-AFMLKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQA 377
VL+ P A + SK A LK WFHG +S ++AE L+ KNG FLVRESQ
Sbjct: 80 VLSAPQPVADNDAAMNHASKGAVQLKTMPWFHGRISREDAEKLLTPP-KNGRFLVRESQN 138
Query: 378 HPGEYVLSVRVRGRVSHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLR 554
+PG+Y L V GRV + +RR + V E FD+L+ L+EH++ E G R
Sbjct: 139 YPGDYTLCVSYDGRVENYRVRRNEKGLVTVDDDEYFDNLIKLVEHYQK----EADGLCTR 194
Query: 555 LLQPV--SGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEF 677
L PV G L D++ ++ I ++ + GEF
Sbjct: 195 LKAPVDKEGQHLFVVDVNDFKEKGWAIPKASLLKKSLIGKGEF 237
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 71.7 bits (168), Expect = 2e-11
Identities = 31/99 (31%), Positives = 59/99 (59%)
Frame = +3
Query: 261 SKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 440
S F + WFHG ++ +++E ++ G++G FL+RES+ PG++ +SV+ RV H +
Sbjct: 283 SVGFYDRDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVT 342
Query: 441 RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRL 557
R K+ +G +F+ L L++H++ P+ + L+L
Sbjct: 343 RSDKKFCIGQ-RKFESLDDLVDHYKRSPIFSSDDGELKL 380
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 70.5 bits (165), Expect = 4e-11
Identities = 53/184 (28%), Positives = 90/184 (48%), Gaps = 11/184 (5%)
Frame = +3
Query: 174 PAALSACMDASVLAVPAAGAIVSTVLKELSKAFMLKK-----------WFHGVMSAKEAE 320
P+A+ D++ ++ AG + ++ L + A ++ WFHG + +EAE
Sbjct: 330 PSAIGGAFDSNGVSWVGAGGVPTSSLSPTAAAAAQRRAEVNAKLNAMPWFHGRIKREEAE 389
Query: 321 SLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGL 500
+L+ + ++G FLVRES PG+Y L V +V H I+ NK + E FD+L L
Sbjct: 390 NLLKPR-EDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAENKLTIDDDEYFDNLGQL 448
Query: 501 IEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQ 680
+EH+ +++ G +L++ + D E++ +ED Q E N G GEF
Sbjct: 449 VEHY----TLDSDGLCTKLMKALPKEEFCVKDFQDNGWEIK-MEDLQLKE-NIG-KGEFG 501
Query: 681 SLKL 692
+ L
Sbjct: 502 DVML 505
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 67.7 bits (158), Expect = 3e-10
Identities = 34/93 (36%), Positives = 50/93 (53%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG +S AE+L+M ++GS+L+R S GEY LSV+ + V H I +Y
Sbjct: 14 WYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQYQF 73
Query: 465 GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQ 563
G G F L +EHF + P+I +L L+
Sbjct: 74 GMG-VFQSLQEFVEHFANQPLIGGESGILTALR 105
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 66.1 bits (154), Expect = 8e-10
Identities = 39/100 (39%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 455
W+HG +S + E+L+ E+G+ +GSFLVRES + G++VLSV VSH IRR
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQIRRHSEDAF 68
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSG 575
+ + + L LIEH+ + I + G L L PV G
Sbjct: 69 FSIDENTKIHGLESLIEHYVNTKGILSEG--LSLTVPVKG 106
Score = 43.2 bits (97), Expect = 0.007
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
W+HG + EAE+ I + K+G+FLVR S + E VL++ + +IR+Q +
Sbjct: 286 WYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK-ERVLTLINESLFYNYIIRKQDDYLF 344
Query: 462 VGSGEQFDDLVGLIEHFRSYP 524
+ +G + L +IE++ P
Sbjct: 345 IDNGPYLESLEHIIEYYSFIP 365
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 65.7 bits (153), Expect = 1e-09
Identities = 36/97 (37%), Positives = 52/97 (53%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
L WFHG ++ +AE L+ + G FLVRES PG+Y L V G+V H I + K
Sbjct: 15 LMPWFHGKITRNQAEQLLCPP-ETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGK 73
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
+ E F++L+ L+EH+ + G RLL+P
Sbjct: 74 LTIDEEEYFENLMQLVEHYTK----DADGLCTRLLKP 106
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 65.7 bits (153), Expect = 1e-09
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 458
WFHG +S + AE ++ ++G NG F+VRES + G++VLSV + V H IRR + +
Sbjct: 9 WFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRRHGDDAFF 68
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDI 599
+ L LIEH+R E+S ++ LQ V + HD+
Sbjct: 69 SIDDHMPIHGLDSLIEHYR-----ESSNGLVTRLQTVCQSGPPPHDV 110
>UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to
Tyrosine-protein phosphatase non-receptor type 11
(Protein-tyrosine phosphatase SYP) (PTP-1D) (SH-PTP2)
(SHP-2) (Shp2); n=1; Macaca mulatta|Rep: PREDICTED:
similar to Tyrosine-protein phosphatase non-receptor
type 11 (Protein-tyrosine phosphatase SYP) (PTP-1D)
(SH-PTP2) (SHP-2) (Shp2) - Macaca mulatta
Length = 162
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/69 (42%), Positives = 45/69 (65%)
Frame = +3
Query: 414 GRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAH 593
G+ + L+ + KYDVG GE+FD L L EH++ PM+ET VL+ QP++ T + A
Sbjct: 92 GKEAEKLLTDKELKYDVGGGERFDSLTDLAEHYKKNPMVETLSAVLQFKQPLNTTCINAA 151
Query: 594 DIDQKVQEM 620
+I+ +VQE+
Sbjct: 152 EIESRVQEL 160
Score = 32.7 bits (71), Expect = 9.5
Identities = 12/20 (60%), Positives = 16/20 (80%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEK 338
+KWFHG +S KEAE L+ +K
Sbjct: 83 EKWFHGHLSGKEAEKLLTDK 102
>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4200-PA - Tribolium castaneum
Length = 1233
Score = 65.3 bits (152), Expect = 1e-09
Identities = 40/105 (38%), Positives = 60/105 (57%), Gaps = 8/105 (7%)
Frame = +3
Query: 279 KKWFHGVMS--AKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-- 440
+KWFHG ++ +EAE L+ +G+FLVR S GEY LS G+V+H IR
Sbjct: 573 EKWFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSK 632
Query: 441 --RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+QH +Y + + FD L LI H+R+ P++ T+ + L +PV
Sbjct: 633 PDKQHTRYYLTDAKYFDSLYSLITHYRNCPLV-TAEFSITLQEPV 676
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/83 (27%), Positives = 45/83 (54%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++W+H +A+ ++ G+FLVR S+ Y +S R ++ H I+ + Y
Sbjct: 685 EEWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLY 744
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+G+ E F+ LV LI ++ ++P+
Sbjct: 745 TIGNVE-FESLVELINYYENHPL 766
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/97 (36%), Positives = 54/97 (55%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
L WFHG ++ ++AE L+ + G FLVRES +PG+Y L V G+V H I +K
Sbjct: 79 LMPWFHGKITREQAERLLYPP-ETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASK 137
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
+ F++L+ L+EH+ S + G RL++P
Sbjct: 138 LSIDEEVYFENLMQLVEHYTS----DADGLCTRLIKP 170
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-- 455
WFHG +S ++AESL++E G+ NG+FLVRES + G+YVLSV G V+H IR+
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68
Query: 456 YDVGSGEQFDDLVGLIEHFR 515
+ + L LIE+++
Sbjct: 69 FSIDDETTIHGLETLIEYYQ 88
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
W+HG + EA +L+ + G +GSFLVR S+ H G VL+V H I+++ N
Sbjct: 283 WYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQIQKRRNFLF 342
Query: 462 VGSGEQFDDLVGLIEHFRSYP 524
+ +G L +IEH+R P
Sbjct: 343 IDNGPYLPSLEHVIEHYRCMP 363
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 64.1 bits (149), Expect = 3e-09
Identities = 26/84 (30%), Positives = 54/84 (64%), Gaps = 1/84 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRE-SQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
++W+H +S +AE ++M ++G+FLVR+ S++H Y +S R G++ H I+++
Sbjct: 617 REWYHSSLSRVQAEHMLMRVPRDGAFLVRKRSESH--SYAISFRAEGKIKHCRIQQEGRL 674
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPM 527
+ +GS +F+ LV L+ ++ +P+
Sbjct: 675 FMLGSSAEFESLVDLVNYYEKHPL 698
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 13/96 (13%)
Frame = +3
Query: 279 KKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 431
++WFHG + + AE L+ + K+G+FLVRES+ G+Y LS GRV H
Sbjct: 500 ERWFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHC 559
Query: 432 LIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 527
I RQ + ++ + FD L L+ H+R P+
Sbjct: 560 RIHSRQESGSTRFYLTDNLVFDSLYRLMCHYRDTPL 595
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/114 (33%), Positives = 61/114 (53%)
Frame = +3
Query: 228 GAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 407
G ++S V +E+ + + W+HG + E + L+ K+G FLVR+SQ PG YVLSV
Sbjct: 509 GLVLSPVGQEVERPLEQQTWYHGAIPRLEVQQLLT---KDGDFLVRKSQEKPG-YVLSVH 564
Query: 408 VRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
G H L++ + N Y + GE F + LI+ +++ T + L +PV
Sbjct: 565 WSGACKHFLVQNKDNMYCL-DGESFHTIPQLIQQYQTSQQHVTKKSEVVLRRPV 617
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 63.7 bits (148), Expect = 4e-09
Identities = 28/106 (26%), Positives = 62/106 (58%), Gaps = 1/106 (0%)
Frame = +3
Query: 258 LSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
L+ F W++G ++ +AE + E+G G FL+R+S++ P ++ +S++ +G+ H +
Sbjct: 19 LTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKV 78
Query: 438 RRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIET-SGDVLRLLQPVS 572
+ + Y +G +F + L+EH++ P+ + G+ L L++ +S
Sbjct: 79 QLKETVYCIGQ-RKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS 123
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 63.7 bits (148), Expect = 4e-09
Identities = 31/79 (39%), Positives = 47/79 (59%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HGV+ E E ++ K G +LVR+S PG+YVLSV G+VSH +I + Y +
Sbjct: 9 WYHGVLKRVETEGILNGKPP-GVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67
Query: 465 GSGEQFDDLVGLIEHFRSY 521
G + F DL +IE ++ +
Sbjct: 68 GD-QTFPDLPSIIEFYKKH 85
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 63.3 bits (147), Expect = 6e-09
Identities = 28/85 (32%), Positives = 49/85 (57%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K WFHG +S +EA + + G G FL+R S +PG+Y LS R + I++Q +Y
Sbjct: 235 KVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQKQQRQY 294
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIE 533
+G G ++ L +++H++ +I+
Sbjct: 295 VMG-GRYYNSLDAIVDHYKKEEIID 318
Score = 53.6 bits (123), Expect = 5e-06
Identities = 28/77 (36%), Positives = 42/77 (54%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+HG + + AE + K GS+LVRES+ PG YVLS + ++H + +
Sbjct: 67 EWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAVCGDFY 126
Query: 462 VGSGEQFDDLVGLIEHF 512
VG G QF L LI ++
Sbjct: 127 VG-GRQFQTLPELIGYY 142
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 63.3 bits (147), Expect = 6e-09
Identities = 23/83 (27%), Positives = 51/83 (61%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++W+H ++ +AE ++M ++G+FLVR+ H Y +S R G++ H I+++ +
Sbjct: 685 REWYHSSLTRVQAEHMLMRVPRDGAFLVRKRSEH-NSYAISFRAEGKIKHCRIQQEGRLF 743
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+GS +F+ L+ L+ ++ +P+
Sbjct: 744 MLGSSAEFESLMDLVSYYEKHPL 766
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 13/96 (13%)
Frame = +3
Query: 279 KKWFHGVMSA-----KEAESLIMEK----GKNGSFLVRESQAHPGEYVLSVRVRGRVSHV 431
++WFHG + + AE L+ E K+G+FLVRES+ G+Y LS GRV H
Sbjct: 568 ERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHC 627
Query: 432 LIR-RQHN---KYDVGSGEQFDDLVGLIEHFRSYPM 527
I RQ + ++ + FD L LI H+R P+
Sbjct: 628 RIHSRQESGSTRFYLTDNLVFDSLYRLICHYRDTPL 663
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 63.3 bits (147), Expect = 6e-09
Identities = 39/122 (31%), Positives = 63/122 (51%)
Frame = +3
Query: 243 TVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 422
T+ ++ S + WFHG +S + AESL+M + ++G FLVRES PG+Y L V + +V
Sbjct: 87 TLPRDASGQLIPMPWFHGKISRELAESLLMPR-EDGLFLVRESAHFPGDYTLCVCFQDQV 145
Query: 423 SHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDID 602
H ++ ++ K + F L L++H+ + G RL +PV R ID
Sbjct: 146 DHYRMQGKNGKLTIDEEVYFSSLEELVQHYEK----DADGLCTRLRKPVVKQGGREFKID 201
Query: 603 QK 608
+
Sbjct: 202 AR 203
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 63.3 bits (147), Expect = 6e-09
Identities = 31/116 (26%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +3
Query: 219 PAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 398
PA +S S F ++W++G ++ +AE + E+G G FL+R+S++ P ++ +
Sbjct: 263 PAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSV 322
Query: 399 SVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETS-GDVLRLLQ 563
S++ G+ H ++ N Y +G +F + L+EH++ P+ + G+ L L++
Sbjct: 323 SLKASGKNKHFKVQLVDNVYCIGQ-RRFHTMDELVEHYKKAPIFTSEHGEKLYLVR 377
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 63.3 bits (147), Expect = 6e-09
Identities = 38/111 (34%), Positives = 56/111 (50%)
Frame = +3
Query: 237 VSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRG 416
+S ++ K + W+HG + EA+ L+ K G FLVRES PGEYVLSV G
Sbjct: 444 LSDMISISEKPLAEQDWYHGAIPRIEAQELLK---KQGDFLVRESHGKPGEYVLSVYSDG 500
Query: 417 RVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+ H +I+ N Y G F ++ LI+H + + T + LL P+
Sbjct: 501 QRRHFIIQYVDNMYRF-EGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPI 550
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 62.5 bits (145), Expect = 1e-08
Identities = 24/81 (29%), Positives = 50/81 (61%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF+ +S +AE +M ++G+FL+R+ + P + ++ + G+V H I+++ +Y +
Sbjct: 632 WFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLL 691
Query: 465 GSGEQFDDLVGLIEHFRSYPM 527
G+ F+ LV L+ +FR+ P+
Sbjct: 692 GTTTYFESLVELVSYFRNRPL 712
Score = 46.4 bits (105), Expect = 7e-04
Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 11/92 (11%)
Frame = +3
Query: 285 WFHGVMS--AKEAESLIMEK-----GKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR- 440
WFHG M + AE LI E G++G+FLVR S Y LS GRV H +R
Sbjct: 517 WFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWRNGRVQHCRVRV 576
Query: 441 -RQHNK--YDVGSGEQFDDLVGLIEHFRSYPM 527
Q + Y + + F L+ LI+H+R P+
Sbjct: 577 GNQGGRPYYFLTANLHFPSLISLIQHYRENPL 608
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/105 (25%), Positives = 63/105 (60%), Gaps = 1/105 (0%)
Frame = +3
Query: 261 SKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 440
S F K+W++G ++ +AE + ++G G FL+R+S++ P ++ +S++ + + H ++
Sbjct: 289 SGRFAGKEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQ 348
Query: 441 RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIET-SGDVLRLLQPVS 572
+ + Y +G +F + L+EH++ P+ + GD L L++ ++
Sbjct: 349 LKESLYCIGQ-RKFHSMEELVEHYKKAPIFTSEQGDKLYLVKALA 392
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 62.5 bits (145), Expect = 1e-08
Identities = 29/78 (37%), Positives = 46/78 (58%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG ++ EAE L+ + ++G FLVRES PG+Y L V + +V H ++ NK +
Sbjct: 479 WFHGSITRDEAEHLLQPR-EDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTI 537
Query: 465 GSGEQFDDLVGLIEHFRS 518
E F++L L+ H+ +
Sbjct: 538 DDEEYFENLGQLVAHYEA 555
>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1 - Homo sapiens (Human)
Length = 1290
Score = 62.5 bits (145), Expect = 1e-08
Identities = 26/83 (31%), Positives = 51/83 (61%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K+W+H ++ +AE ++M ++G+FLVR+ + P Y +S R G++ H ++++
Sbjct: 666 KEWYHASLTRAQAEHMLMRVPRDGAFLVRK-RNEPNSYAISFRAEGKIKHCRVQQEGQTV 724
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+G+ E FD LV LI ++ +P+
Sbjct: 725 MLGNSE-FDSLVDLISYYEKHPL 746
Score = 53.6 bits (123), Expect = 5e-06
Identities = 45/132 (34%), Positives = 65/132 (49%), Gaps = 17/132 (12%)
Frame = +3
Query: 252 KELSKAFML---KKWFHGVMSAKE-----AESLIMEK-----GKNGSFLVRESQAHPGEY 392
KE+S + L +KWFHG + A AE L+ E +GSFLVRES+ G+Y
Sbjct: 536 KEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDY 595
Query: 393 VLSVRVRGRVSHVLIRRQHN----KYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLL 560
LS G+V H I + + K+ + FD L LI H++ P + + +RL
Sbjct: 596 TLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVP-LRCNEFEMRLS 654
Query: 561 QPVSGTRLRAHD 596
+PV T AH+
Sbjct: 655 EPVPQT--NAHE 664
>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
Zgc:158474 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 906
Score = 62.1 bits (144), Expect = 1e-08
Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 4/113 (3%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
+WFHG +S +A L++ G +G FLVR+S+ GEYVL+ +G+ H+ + +
Sbjct: 714 QWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEDG 773
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPM-IETSG-DVLRLLQPVSGTRLRAHDIDQK 608
F + ++EHFR +P+ +E+ G + L+ V T +R D+ +
Sbjct: 774 QCRVQHLWFQSIFDMLEHFRVHPIPLESGGASDVTLISFVGATNVRQPDLTSR 826
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 379 WYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 437
Query: 462 VGSGEQFDDLVGLIEH 509
V S +F+ L L+ H
Sbjct: 438 VSSESRFNTLAELVHH 453
>UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;
n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase
protein 2 - Caenorhabditis elegans
Length = 668
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/150 (30%), Positives = 77/150 (51%), Gaps = 6/150 (4%)
Frame = +3
Query: 255 ELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 434
E + L +W+HG + A A L+ + KNG++L+R SQ PG V+S + G+V H+
Sbjct: 124 EEQRRTQLYRWWHGNLPASSANKLLQTE-KNGTYLLRASQHIPGALVISAKTEGQVVHLT 182
Query: 435 IRRQHN--KYDV-GSGEQFDDLVGLIEHFRSYPMIE--TSGDVLRLLQPVSGTRLRAH-D 596
I + + ++++ G +F LI+ + P++E + VL L +P+ T + A
Sbjct: 183 IYQDPSTGRFNIDGDRTKFQSAWLLIDSYSKNPIVEKGEASRVLYLEEPLFNTFIEADLF 242
Query: 597 IDQKVQEMQGIEDRQKMECNTGFDGEFQSL 686
+D+ + I R+ ME TG EF L
Sbjct: 243 VDRFEIIRRPINPRESME-KTGISEEFDRL 271
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/103 (28%), Positives = 57/103 (55%), Gaps = 9/103 (8%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-RGRVSHVLIRR-QHNKYD 461
F+ ++ ++AE L+ E G++G FL+R S+++P + +SVRV ++ H+ + + + +
Sbjct: 11 FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70
Query: 462 VGSGE-----QFDDLVGLIEHFRSYP--MIETSGDVLRLLQPV 569
+ E QF + L E + +P + E +G L L +PV
Sbjct: 71 IFEDERTTPNQFGSITELAEFYMEFPEKLREKNGLFLELKKPV 113
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 466 WYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 524
Query: 462 VGSGEQFDDLVGLIEH 509
V S +F+ L L+ H
Sbjct: 525 VSSESRFNTLAELVHH 540
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 116 WYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 174
Query: 462 VGSGEQFDDLVGLIEH 509
V S +F+ L L+ H
Sbjct: 175 VSSESRFNTLAELVHH 190
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 61.3 bits (142), Expect = 2e-08
Identities = 30/93 (32%), Positives = 50/93 (53%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG ++ AE+L++ G +GS+L+R+S G Y LSVR + V H + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 465 GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQ 563
G E F L ++HF + P+I + L +L+
Sbjct: 95 GFNE-FSSLKDFVKHFANQPLIGSETGTLMVLK 126
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 13 WYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 71
Query: 462 VGSGEQFDDLVGLIEH 509
V S +F+ L L+ H
Sbjct: 72 VSSESRFNTLAELVHH 87
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 127 WYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 185
Query: 462 VGSGEQFDDLVGLIEH 509
V S +F+ L L+ H
Sbjct: 186 VSSESRFNTLAELVHH 201
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/96 (27%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K W++G ++ + ++++ G +G FL+R+S+ + G+Y +S++ GR H + + N Y
Sbjct: 446 KSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMY 505
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM-IETSGDVLRLLQ 563
+G +F L L++H++ P+ G+ L L++
Sbjct: 506 CIGQ-RKFHSLDQLVDHYQRAPIYTNKQGEKLYLVR 540
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 60.1 bits (139), Expect = 5e-08
Identities = 39/95 (41%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ-HNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 254 WYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF 312
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
V +F+ L L+ H S P E G + LL P
Sbjct: 313 VTQEAKFNTLAELVHH-HSVPH-EGHGLITPLLYP 345
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 59.3 bits (137), Expect = 1e-07
Identities = 32/76 (42%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 76 WYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 134
Query: 462 VGSGEQFDDLVGLIEH 509
V +F+ L L+ H
Sbjct: 135 VSPESRFNTLAELVHH 150
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 58.8 bits (136), Expect = 1e-07
Identities = 23/83 (27%), Positives = 46/83 (55%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K W+H + AE ++ +G+FLVR++ Y +S R G++ H +I+++ +
Sbjct: 670 KPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLF 729
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+G+ QF+ LV L+ ++ P+
Sbjct: 730 TIGNA-QFESLVELVNYYEKKPL 751
Score = 56.0 bits (129), Expect = 9e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 8/91 (8%)
Frame = +3
Query: 279 KKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-- 440
+KWFHG + ++AE L+ E +G+FLVRES G++ LS + V+H IR
Sbjct: 558 EKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSK 617
Query: 441 --RQHNKYDVGSGEQFDDLVGLIEHFRSYPM 527
R KY + FD L LI H++ YP+
Sbjct: 618 QERGQTKYYLIDNLAFDSLYSLITHYQKYPL 648
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 58.4 bits (135), Expect = 2e-07
Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KYD 461
W+HG +S AE L+ G NGSFLVRES++ PG+ +S+R GRV H I + K
Sbjct: 175 WYHGRISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSDGKMY 233
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
V + F+ L L+ H + M+ G + +LL P
Sbjct: 234 VTTESIFNTLAELVHH---HSML-ADGLITQLLYP 264
>UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG17367-PB, isoform B - Tribolium castaneum
Length = 488
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +3
Query: 219 PAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEY 392
P+ G +S + ++ + + WFHG + EA +L++ G G FLVR+S+ GE+
Sbjct: 301 PSTGDNIS-METDIGQTLKKEFWFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEF 359
Query: 393 VLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPM-IETSGD 545
VL+ +GR H+ + F + ++EHFR P+ +E+ G+
Sbjct: 360 VLTFNFQGRAKHLRMTINDQGQCRVQHFWFQSIYEMLEHFRQQPIPLESGGN 411
>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
(Human)
Length = 756
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 2/88 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIME--KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG++S +A L++ G +G FLVR+S+ GEYVL+ +G+ H+ +
Sbjct: 527 WFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQ 586
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSG 542
F + ++EHFR +P+ SG
Sbjct: 587 CRVQHLWFQSIFDMLEHFRVHPIPLESG 614
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 58.4 bits (135), Expect = 2e-07
Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Frame = +3
Query: 228 GAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEK-GKNGSFLVRESQAHPGEYVLSV 404
G I S + E K+ ++WF G + EAE ++ + + GSFL+R+S+ PG++ LSV
Sbjct: 104 GYIPSNYVAEY-KSLDAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSV 162
Query: 405 RVRGRVSHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
+ + RV H +RR + V F L L++H++ IET G +LL P
Sbjct: 163 KDQDRVRHYRVRRLEDGSLFVTRRSTFQILHELVDHYK----IETDGLCCKLLYP 213
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/97 (32%), Positives = 48/97 (49%)
Frame = +3
Query: 222 AAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 401
AAGA+ L WFHG +S +EA + + ++G FLVRES HPG+YVL
Sbjct: 101 AAGALREREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLC 159
Query: 402 VRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHF 512
V V H + + + F +L+ ++EH+
Sbjct: 160 VSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHY 196
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
K WFHG M K+A I + G K+G FL+R S P VLS+ G V + I +
Sbjct: 349 KPWFHGSMDRKKALESIQKHGAKDGQFLLRSSANKPDTMVLSMAANGTVFNFEINTKMES 408
Query: 456 YDVGSGEQFDDLVGLIEHFRSY 521
+ + G FD L LI+H+ Y
Sbjct: 409 FYIDDGPYFDTLEQLIDHYSRY 430
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KY 458
WFHG ++ A ++ G G+FLVRES + G+YV+S+ G H I+ + Y
Sbjct: 76 WFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGLPQHFQIQCMGDFYY 135
Query: 459 DVGSGEQFDDLVGLIEHFR 515
+ +G F L LI ++R
Sbjct: 136 KIDNGPLFQGLDQLINYYR 154
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-QHNKYD 461
W+HG + AE L+ G NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 174 WYHGRICRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSEGKMF 232
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
V + +F+ L L+ H + M+ G + +LL P
Sbjct: 233 VTTESKFNTLAELVHH---HSML-ADGLITQLLYP 263
>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
str. PEST
Length = 1230
Score = 58.0 bits (134), Expect = 2e-07
Identities = 25/83 (30%), Positives = 50/83 (60%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K+W+H + +++E ++ + ++G+FLVR S+ +V+S R G+ H IR + Y
Sbjct: 680 KEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEGRLY 739
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
++G G +F+ LV L+ + +P+
Sbjct: 740 EMG-GMEFESLVDLVNFYSKHPL 761
Score = 47.2 bits (107), Expect = 4e-04
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 8/87 (9%)
Frame = +3
Query: 279 KKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 446
+ WFHG +S +EAE L+ + +G+FLVRES G+Y LS +G+ +H I+ +
Sbjct: 568 ENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIKLK 627
Query: 447 HN----KYDVGSGEQFDDLVGLIEHFR 515
+ KY + F+ L LI ++R
Sbjct: 628 QDKGVTKYYLMENVLFESLYSLIMYYR 654
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 58.0 bits (134), Expect = 2e-07
Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 7/115 (6%)
Frame = +3
Query: 198 DASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQ 374
+A +A G I S + + + ++W+ G M K+AE L++ G + G FLVRES+
Sbjct: 130 EARSIATGKNGYIPSNYVAP-ADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESE 188
Query: 375 AHPGEYVLSVR----VRG-RVSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHFRSY 521
G Y LS+R +RG V H IR+ N Y + + QFD L L++H+ +
Sbjct: 189 TTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH 243
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 57.6 bits (133), Expect = 3e-07
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
Frame = +3
Query: 219 PAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 398
P A + S+ S A + WFH ++S + E L+ K +G+FLVRES PG++ L
Sbjct: 129 PGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGK-PDGTFLVRESTNFPGDFTL 187
Query: 399 SVRVRGRVSHVLIRR-QHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+ G+V H I + + E F +L L+ H++ + G RL+ P+
Sbjct: 188 CMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKR----DADGLCHRLVTPI 241
>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
(Human)
Length = 632
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 3/89 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNK 455
WFHG +S +A L++ G +G F++R+S+ PGEYVL+ +G+ H+ L H +
Sbjct: 417 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 476
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSG 542
V F ++ ++ HF ++P+ SG
Sbjct: 477 CHV-QHLWFQSVLDMLRHFHTHPIPLESG 504
>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
transduction protein lnk-realted; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to signal
transduction protein lnk-realted - Nasonia vitripennis
Length = 458
Score = 57.2 bits (132), Expect = 4e-07
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Frame = +3
Query: 255 ELSKAFMLKKWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSH 428
+LS + WFHG + +A L++ +G+FLVR+S+ GEYVL+ +GR H
Sbjct: 260 DLSSSLREYPWFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKH 319
Query: 429 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSG 542
+ + + F + +++HFR P+ SG
Sbjct: 320 LRMTLTDQGHCRVQHLSFPAIYDMLDHFRQNPIPLESG 357
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 57.2 bits (132), Expect = 4e-07
Identities = 34/90 (37%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
WF G M+ A S +M N GSFLVR S++ YVLSVR + H I + +++
Sbjct: 134 WFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGDQFY 193
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVL 551
V + +F +V +IEH++S+P+ + GD+L
Sbjct: 194 VDALFKFSSIVEVIEHYQSHPL--SIGDLL 221
>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
n=2; Endopterygota|Rep: Signal transduction protein
lnk-realted - Aedes aegypti (Yellowfever mosquito)
Length = 564
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG ++ EA L++ G +G FLVR+S+ GE+VL+ +G+ H+ +
Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTLNDLGQ 478
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSG 542
F + ++EHFR +P+ SG
Sbjct: 479 CRVQHLWFPSITEMLEHFRQHPIPLESG 506
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 57.2 bits (132), Expect = 4e-07
Identities = 29/85 (34%), Positives = 45/85 (52%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
K WFHG +S +EA +L+M G+ SFLVR S PG+Y L R + I N
Sbjct: 349 KIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQ 408
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIE 533
+ G ++ + +I+H+R ++E
Sbjct: 409 FMMGGRYYNSIGDIIDHYRKEQIVE 433
Score = 54.4 bits (125), Expect = 3e-06
Identities = 34/98 (34%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKY 458
+W+HG + AE + + GK+GS+L+RES PG +VLS + V+H I Y
Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
+G G +F L LI ++ S+ G+ +LL PV+
Sbjct: 240 YIG-GRRFSSLSDLIGYY-SHVSCLLKGE--KLLYPVA 273
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+HG + AE + + + GS+LVRES PG YVLS R ++H I Y
Sbjct: 76 QWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 135
Query: 462 VGSGEQFDDLVGLIEHF 512
+G G QF+ L+ L+ ++
Sbjct: 136 IG-GRQFNSLMDLVAYY 151
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/98 (29%), Positives = 50/98 (51%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFH ++ EA ++++ G GSFLVR S PG+Y L + ++ I ++ +Y +
Sbjct: 246 WFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 304
Query: 465 GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGT 578
G G F+ L +I +R ++E V ++ GT
Sbjct: 305 G-GRTFECLDAVINRYRKEQIVEGHTLVQAMVTEPDGT 341
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 56.8 bits (131), Expect = 5e-07
Identities = 30/77 (38%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 458
W+HG +S +AE L+ G+ +GSFLVR+S GEYVLS+ +G+ H +I R
Sbjct: 9 WYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRHPDGSV 68
Query: 459 DVGSGEQFDDLVGLIEH 509
+ G +FD + LI++
Sbjct: 69 AIQDGAKFDSPIELIQY 85
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKY 458
WFHG +S +E+E + G ++G FLVRE + + L V V+ + H L+ +
Sbjct: 163 WFHGAISREESEQRMKAFGLRDGLFLVRE-RTEVNSFALCVAVKNDIYHYLLEMNTLGQL 221
Query: 459 DVGSGEQFDDLVGLIEHFRSYP 524
+ +G +F++L+ +++H+ P
Sbjct: 222 SIENGRKFENLLQVVDHYSRTP 243
>UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo
sapiens (Human)
Length = 428
Score = 56.8 bits (131), Expect = 5e-07
Identities = 32/95 (33%), Positives = 56/95 (58%), Gaps = 8/95 (8%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIR--RQH 449
+W+ G S + E M++ K+GSFLVR+ E YVL+V +V +V IR ++
Sbjct: 308 EWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERN 367
Query: 450 NKYDVGSG----EQFDDLVGLIEHFRSYPMIETSG 542
++ +G+G E+FD + +IEH++++P+I G
Sbjct: 368 QQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDG 402
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 56.4 bits (130), Expect = 7e-07
Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Frame = +3
Query: 240 STVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGR 419
S+ L L + + W+HG +S + E L+ G GSFLVR S++ PG+ ++VR GR
Sbjct: 63 SSPLSLLEPSLLSYSWYHGAVSRQAGEHLL-RSGITGSFLVRASESAPGQLSVTVRHLGR 121
Query: 420 VSHVLIRR-QHNKYDVGSGEQFDDLVGLIEH 509
V H I + + + +F +V LIEH
Sbjct: 122 VYHYRISQDSRGLFYITEAHRFPTVVQLIEH 152
>UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c); n=8;
Theria|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c) -
Homo sapiens (Human)
Length = 473
Score = 56.4 bits (130), Expect = 7e-07
Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 1/96 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H+L+
Sbjct: 378 WFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT 434
Query: 465 GSGEQFDDLVGLIE-HFRSYPMIETSGDVLRLLQPV 569
+F+ + LI H ++ I ++G L L QPV
Sbjct: 435 -KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPV 469
>UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46;
Tetrapoda|Rep: SHC-transforming protein 1 - Homo sapiens
(Human)
Length = 583
Score = 56.4 bits (130), Expect = 7e-07
Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 1/96 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H+L+
Sbjct: 488 WFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT 544
Query: 465 GSGEQFDDLVGLIE-HFRSYPMIETSGDVLRLLQPV 569
+F+ + LI H ++ I ++G L L QPV
Sbjct: 545 -KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPV 579
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 56.4 bits (130), Expect = 7e-07
Identities = 30/96 (31%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
W+ G +S + AE ++M++ G+FL+RES++ PGE+ +SV +V H ++R KY
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+ E+F+ L L++ +R+ + + LR +P+
Sbjct: 120 LWE-EKFNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 56.0 bits (129), Expect = 9e-07
Identities = 29/95 (30%), Positives = 53/95 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+ G +S + AE L++ G+ G FLVR+S+++PG+ +S+R R H ++ +
Sbjct: 301 WYFGRISRERAEDLLLH-GREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVDGLLKI 359
Query: 465 GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
G+ F D+ LI H+ + P+ + + L L P+
Sbjct: 360 GN-RTFVDMNALINHYTTSPIFSSPTEKLFLTGPL 393
>UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus
norvegicus|Rep: SH2B adapter protein 3 - Rattus
norvegicus (Rat)
Length = 368
Score = 56.0 bits (129), Expect = 9e-07
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 3/126 (2%)
Frame = +3
Query: 159 LGVLAPAALSACMDASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEK 338
LGVL A L + G ++ ++ WFHG +S A L+ +
Sbjct: 77 LGVLGHVAPLRVTTTIFLPGASPGVMLDPACQKTDHFLSCYPWFHGPISRVRAAQLVQLQ 136
Query: 339 GKN--GSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLVGLIEH 509
G + G FLVR+S++ GEYVL+ ++GR H+ L+ + + V F +V ++ H
Sbjct: 137 GPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERGQCRV-QHLHFPSVVDMLRH 195
Query: 510 FRSYPM 527
F+ P+
Sbjct: 196 FQRSPI 201
>UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2
domain protein C1) (Src homology 2
domain-containing-transforming protein C1).; n=2;
Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain
protein C1) (Src homology 2
domain-containing-transforming protein C1). - Takifugu
rubripes
Length = 526
Score = 55.6 bits (128), Expect = 1e-06
Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 2/149 (1%)
Frame = +3
Query: 129 MSKDNPRLSRLGVLAPAALSACMDASVLAVPA-AGAIVSTVLKELSKAFMLKKWFHGVMS 305
+ K PR++ G + A L V +G ++ L + + WFHG +S
Sbjct: 379 VDKPRPRVASNGNMHRDAFDMKPFDDALGVSGHSGTSSASAAPPLVQQLQCEAWFHGGLS 438
Query: 306 AKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFD 485
KEAE L+ ++G FLVRES PG+YVL+ + G+ H+L+ +F+
Sbjct: 439 RKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRT-KDHRFE 494
Query: 486 DLVGLIE-HFRSYPMIETSGDVLRLLQPV 569
+ LI H + I ++G + L QPV
Sbjct: 495 SVSHLISYHMDNRLPIISAGSEVCLKQPV 523
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 55.6 bits (128), Expect = 1e-06
Identities = 30/79 (37%), Positives = 42/79 (53%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+HG + AES + K GS+LVRES PG YVLS R ++H I +
Sbjct: 83 EWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFY 142
Query: 462 VGSGEQFDDLVGLIEHFRS 518
+G G QF L L+ ++ S
Sbjct: 143 IG-GRQFISLSDLVGYYTS 160
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/83 (31%), Positives = 44/83 (53%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFH + EA ++++ G GSFLVR S PG+Y L + ++ I ++ +Y +
Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 311
Query: 465 GSGEQFDDLVGLIEHFRSYPMIE 533
G G F+ L +I +R ++E
Sbjct: 312 G-GRTFECLDAVINRYRKEQIVE 333
>UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34;
Euteleostomi|Rep: SHC-transforming protein 3 - Homo
sapiens (Human)
Length = 594
Score = 55.6 bits (128), Expect = 1e-06
Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 6/127 (4%)
Frame = +3
Query: 207 VLAVPAAGAIVSTVLKELSKAFMLKK-----WFHGVMSAKEAESLIMEKGKNGSFLVRES 371
VL+ A+ +S V A ML++ W+ G MS KEAE L+ K+G FLVR+S
Sbjct: 468 VLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLE---KDGDFLVRKS 524
Query: 372 QAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLI-EHFRSYPMIETSGDV 548
+PG +VL+ G+ H+L+ FD + LI H S I ++G
Sbjct: 525 TTNPGSFVLTGMHNGQAKHLLLVDPEGTIRT-KDRVFDSISHLINHHLESSLPIVSAGSE 583
Query: 549 LRLLQPV 569
L L QPV
Sbjct: 584 LCLQQPV 590
>UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 520
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFHG MS KE E L+ +G FLVRES +YVLS G H+L+ K
Sbjct: 421 EEWFHGPMSRKEGEPLL---SNDGDFLVRESTTAKDQYVLSGMQNGTPKHLLLVDPQGKV 477
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM-IETSGDVLRLLQPV 569
++FD + LI + R+ + I ++G + L PV
Sbjct: 478 RT-KDKEFDSVSHLINYHRNNRLPIISAGSAVHLKTPV 514
>UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n=4;
Euteleostomi|Rep: UPI00015A3F46 UniRef100 entry - Danio
rerio
Length = 217
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S A L++ G +G F++R+S+ PGEYVL+ +G+ H+ + +
Sbjct: 117 WFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSVNDSGQ 176
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSG 542
F + ++ HF ++P+ SG
Sbjct: 177 CHVHHLWFQTVADMLRHFHTHPIPLESG 204
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 55.2 bits (127), Expect = 2e-06
Identities = 36/97 (37%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK-YD 461
W+ G +S EA++ + + K+G FLVR+S G+YVLSV +VSH +I NK +
Sbjct: 14 WYFGPVSRHEAQNRLQGQ-KHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKRFK 72
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
+G E F+ L L+E F Y ++T+ L++P S
Sbjct: 73 IGDRE-FEHLPALLE-FYKYHYLDTT----TLIEPAS 103
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
W+HG +S AE L+ NGSFLVRES++ PG+ +S+R GRV H I K
Sbjct: 173 WYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 462 VGSGEQFDDLVGLIEH 509
V + +F L L+ H
Sbjct: 232 VTAESRFSTLAELVHH 247
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 54.8 bits (126), Expect = 2e-06
Identities = 23/54 (42%), Positives = 37/54 (68%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
KW+HG +S + A+ L+ + ++G+FLVRES G++VLS+ +G V H +RR
Sbjct: 9 KWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRR 62
>UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor
receptor bound protein 14; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to growth factor receptor bound
protein 14 - Tribolium castaneum
Length = 655
Score = 54.4 bits (125), Expect = 3e-06
Identities = 32/93 (34%), Positives = 55/93 (59%), Gaps = 8/93 (8%)
Frame = +3
Query: 261 SKAFMLKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
S + + WFH MS +A +L+ + G +G FLVRES+++PG +VL+ + G+V H I
Sbjct: 525 SGVHITQPWFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVLHAQI 584
Query: 438 R------RQHNKYDVGSG-EQFDDLVGLIEHFR 515
R+ + + + SG +F DL+ L+E ++
Sbjct: 585 TPILDPVREAHVFSLDSGVTKFYDLLQLVEFYQ 617
>UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 480
Score = 54.4 bits (125), Expect = 3e-06
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Frame = +3
Query: 261 SKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 440
S+ + WFHG +S KEAE L+ ++G FLVRES PG+YVL+ + G+ H+L+
Sbjct: 377 SQQLQCEAWFHGGLSRKEAERLLT---RDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLV 433
Query: 441 RQHNKYDVGSGEQFDDLVGLIE-HFRSYPMIETSGDVLRLLQPV 569
+F+ + LI H + I ++G + L QPV
Sbjct: 434 DPEGVVRT-KDHRFESVSHLISYHMDNRLPIISAGSEVCLKQPV 476
>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
Amniota|Rep: GRB2-related adapter protein 2 - Homo
sapiens (Human)
Length = 330
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/79 (35%), Positives = 47/79 (59%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
KWFH +S +AE+L+M K + G F++R SQ+ PG++ +SVR V H + R +
Sbjct: 57 KWFHEGLSRHQAENLLMGK-EVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 462 VGSGEQFDDLVGLIEHFRS 518
E+F L L++++R+
Sbjct: 116 FLWTEKFPSLNKLVDYYRT 134
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKYD 461
WFHGV+ EAE + + G FL+RE + G YV+ + +G V H L +
Sbjct: 161 WFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESNNQGQLS 220
Query: 462 VGSGEQFDDLVGLIEHF 512
+ SG FD+L+ ++ +
Sbjct: 221 IKSGRSFDNLMAVVNFY 237
Score = 49.6 bits (113), Expect = 8e-05
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 446
L +WFHG ++ AE+ + +G++L+RES + G YVLSV +V H I+RQ
Sbjct: 6 LLRWFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQRQP 65
Query: 447 HNKYDVGSGEQFDDLVGLIEHFRS 518
+ G QF V L+ H ++
Sbjct: 66 SGMVGIADGPQFPGPVELVNHHKT 89
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 458
WFHG +S +E+E +++ K NG FL+R ++ + G Y L + G+V H I + + K
Sbjct: 168 WFHGKISREESEQIVLIGSKTNGKFLIR-ARDNNGSYALCLLHEGKVLHYRIDKDKTGKL 226
Query: 459 DVGSGEQFDDLVGLIEHF 512
+ G++FD L L+EH+
Sbjct: 227 SIPEGKKFDTLWQLVEHY 244
>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
protein, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
protein, partial - Strongylocentrotus purpuratus
Length = 926
Score = 53.6 bits (123), Expect = 5e-06
Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR----RQHN 452
WFHG +S ++AE LI E NG FLVR+S + PG +VL+VR +G H ++ + H+
Sbjct: 126 WFHGGISREKAEKLIRE---NGDFLVRDSISKPGNFVLTVRWKGVSMHFVVNKVVLKAHS 182
Query: 453 KYD----VGSGEQFDDLVGLIEHF--RSYPMIETSGDVLRLLQPVSGT 578
Y E FD + LI+ + P+ + SG V++ PV+ T
Sbjct: 183 PYASVQYQFEKECFDAIPSLIKFYVGNCRPVSQASGAVIQ--HPVNRT 228
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 53.6 bits (123), Expect = 5e-06
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKY 458
W++G ++ +AE L++ + K+GSFLVR S++H EY +S R G+V H I+R Y
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309
Query: 459 DVGSGEQFDDLVGLIEHFR 515
V F L LI +++
Sbjct: 310 FVSDRISFATLGELISYYQ 328
Score = 50.0 bits (114), Expect = 6e-05
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKY 458
WF G ++ +A+S L+ + G+FL+R S+ YVLSVR +V H +++ N++
Sbjct: 69 WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128
Query: 459 DVGSGEQFDDLVGLIEHFR 515
V G +F L L+++++
Sbjct: 129 YVEPGRRFSSLAELVDYYQ 147
Score = 39.9 bits (89), Expect = 0.063
Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +3
Query: 318 ESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYDVGSGEQFDDLV 494
E + + G+FL+R S+ YVLSVR +V H +++ N++ V G +F L
Sbjct: 726 EPPVAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLA 785
Query: 495 GLIEHFR 515
L+++++
Sbjct: 786 ELVDYYQ 792
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH-NKYD 461
W+HG +S ++E+ I+ G GSFLVRES+ G+Y +SVR GRV H I + K
Sbjct: 194 WYHGKISRSDSEA-ILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF 252
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
+ +F L L+ H + G + L+ P S
Sbjct: 253 ITQEVKFRTLGELVHHH----SVHADGLICLLMYPAS 285
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--QHNKY 458
W+ G MS ++A L+M + + G FLVR+S + G++VL VR +VSH +I + Q ++
Sbjct: 13 WYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQGDQI 72
Query: 459 DVGSGEQ-FDDLVGLIEHFR 515
G+Q F D+ L+ ++
Sbjct: 73 RYRIGDQIFPDIPNLLAFYK 92
>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Grb14 - Strongylocentrotus purpuratus
Length = 756
Score = 53.2 bits (122), Expect = 6e-06
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
Frame = +3
Query: 273 MLKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-Q 446
M + WFH ++ E +L ++G +G FL+RESQ PG +VLS +V H I +
Sbjct: 656 MTQPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINMVE 715
Query: 447 HNKYDV-GSGEQFDDLVGLIEHFR 515
Y + G +F DL+ L+E ++
Sbjct: 716 DGVYTIDDGGTRFTDLIQLVEFYQ 739
>UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Gallus gallus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Gallus gallus
Length = 506
Score = 53.2 bits (122), Expect = 6e-06
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S +A L+ G G FLVR+S+ GEYVL+ +GR H+ +
Sbjct: 388 WFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLSLTERGQ 447
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+F + ++ HF YP+
Sbjct: 448 CRVQHLRFSSITEMLHHFHRYPI 470
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 53.2 bits (122), Expect = 6e-06
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 10/109 (9%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+ G +S +EA SL+ + ++G FLVR+S PG+YVLSV +VSH +I +
Sbjct: 13 WYWGRLSRQEAVSLLQGQ-RHGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSNRQS 71
Query: 465 GSG----------EQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTR 581
G G ++FD L L+E ++ + + D L++P+S ++
Sbjct: 72 GPGLAPPRFRIGDQEFDALPALLEFYKIHYL-----DTTTLIEPISKSK 115
>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
Drosophila melanogaster (Fruit fly)
Length = 723
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Frame = +3
Query: 255 ELSKAFMLKKWFHGVMSAKEAESLIM--EKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 428
+L+ + WFHG ++ EA +++ + +G FLVR+S+ GE+VL+ +GR H
Sbjct: 432 DLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKH 491
Query: 429 VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSG 542
+ + F + ++EHFR P+ SG
Sbjct: 492 LRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESG 529
>UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16;
Euteleostomi|Rep: SH2B adapter protein 2 - Mus musculus
(Mouse)
Length = 621
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNK 455
WFHG +S +A L++ G +G F++R+S+ PGE VL+ +G+ H+ L H +
Sbjct: 409 WFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQ 468
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSG 542
V F + ++ HF ++P+ SG
Sbjct: 469 CHV-QHLWFQSVFDMLRHFHTHPIPLESG 496
>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SH2 domain containing 4B - Tribolium
castaneum
Length = 412
Score = 52.8 bits (121), Expect = 8e-06
Identities = 35/108 (32%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Frame = +3
Query: 258 LSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
L ++ ++ WFHG+++ EAE L++++ GSFLVR S+ G Y +S R + + H L+
Sbjct: 300 LDRSNNVESWFHGLITRSEAEKLLLDR-PYGSFLVRLSERIWG-YAISYRAKEKCKHYLV 357
Query: 438 RRQHNKYDVGSGE-QFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGT 578
+G+ + + + L LIE+ R +P+ T G+ L P S T
Sbjct: 358 SAGLKYQFLGNNQIEHETLRDLIEYHRVHPL--TGGEKLVEACPRSAT 403
>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
to Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K) - Apis mellifera
Length = 1256
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/98 (26%), Positives = 56/98 (57%), Gaps = 1/98 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+ G ++ E +++ +G+FLVR++ + GEY L++R G + I +++ KY
Sbjct: 838 EWYWGDITRDEVNEKMIDS-PDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRNGKYG 896
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPVS 572
F ++ L++H+R+ + + + + ++LL PVS
Sbjct: 897 FSEPYNFHSVIELVDHYRNCSLAQYNSTLDIKLLYPVS 934
Score = 35.9 bits (79), Expect = 1.0
Identities = 17/53 (32%), Positives = 32/53 (60%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
K W + S +A+ ++ ++ +G+FL+R S+ G+Y LS+ G V+H +I
Sbjct: 1126 KTWLYLECSRSDADRILADR-PDGTFLIRTSRT--GQYALSIMCNGTVNHCII 1175
>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
protein similar to vertebrate phospholipase C, gamma 2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 270
Score = 52.8 bits (121), Expect = 8e-06
Identities = 35/103 (33%), Positives = 55/103 (53%), Gaps = 11/103 (10%)
Frame = +3
Query: 240 STVLKELSKAFMLKKWFHGVMSAKE--AESLIME--KGKNGS---FLVRESQAHPGEYVL 398
ST +K+ S+ + + WFHG ++ AE L+ + KG +G+ FLVRES G Y +
Sbjct: 39 STQIKDSSELHLSEPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCI 98
Query: 399 SVRVRGRVSHVLI----RRQHNKYDVGSGEQFDDLVGLIEHFR 515
S+ RGR+ H I H + + S E F + LI+++R
Sbjct: 99 SLWTRGRIQHYRIFCFPENGHKIFFLKSKECFPSMCALIDYYR 141
Score = 49.6 bits (113), Expect = 8e-05
Identities = 24/78 (30%), Positives = 42/78 (53%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF+ MS EAE ++ ++G+FL+R+ + LS+R G + H I R+ +KY +
Sbjct: 171 WFYSNMSRAEAEDCLLRIPRDGAFLIRKRNER-DTFALSIRSEGDIKHYKIFRKSSKYVL 229
Query: 465 GSGEQFDDLVGLIEHFRS 518
+F L ++ FR+
Sbjct: 230 ADAYEFFSLEDMVSCFRN 247
>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
Length = 1283
Score = 52.8 bits (121), Expect = 8e-06
Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVSHVLIR-R 443
K WFH +S EAE ++ + +G+FL+R S+ A Y +S R G+V H I
Sbjct: 653 KAWFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVD 712
Query: 444 QHNKYDVGSGEQFDDLVGLIEHFRSYPM 527
+ +Y +GS FD L L++++ + P+
Sbjct: 713 ESGQYCIGSA-IFDSLTELVQYYEANPL 739
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 7/90 (7%)
Frame = +3
Query: 279 KKWFHGVMSAKE--AESLIME-KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ- 446
+KWFHG ++ AE L+ + K NG+FLVRES G+Y LS G+ +H I +
Sbjct: 542 EKWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKS 601
Query: 447 ---HNKYDVGSGEQFDDLVGLIEHFRSYPM 527
++ + FD + LI H++S P+
Sbjct: 602 EGGKTRFYLIDQTLFDSIYELIMHYKSNPL 631
>UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 236
Score = 52.8 bits (121), Expect = 8e-06
Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
W+H ++ +E L+M G G++L+R SQ H Y +S R V H LI Y
Sbjct: 22 WYHPSLTRNASEVLLMTNGVEGNYLLRSSQTH-DMYTVSARSMDSVKHFPLIPDGKGGYK 80
Query: 462 VGSGEQFDDLVGLIEHFRSYPMI 530
G G+ F ++ L+EHFR+ P++
Sbjct: 81 FGIGD-FANIAELMEHFRNIPVL 102
>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9
SCAF8684, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 966
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/154 (31%), Positives = 67/154 (43%), Gaps = 14/154 (9%)
Frame = +3
Query: 279 KKWFHGVMSAKE-----AESLI----MEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSH 428
+KWFHG + A AE L+ ME G +GSFLVRES+ G+Y LS GRV H
Sbjct: 627 EKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWRSGRVQH 686
Query: 429 VLIRRQHN----KYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHD 596
I + K+ + FD L LI H++ + + ++L +PV T AH+
Sbjct: 687 CRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQQV-ALRCNEFEMKLTEPVPQT--NAHE 743
Query: 597 IDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLE 698
+ + M DG F K E
Sbjct: 744 SKEWYHANLSRSQAENMLMRVPRDGAFLVRKRAE 777
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHN 452
+ +W+HG + AE + + GS+L+RES PG +VLS + + V+H I
Sbjct: 182 MPRWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCG 241
Query: 453 KYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
Y +G G +F L LI ++ SY G+ +LL PV+
Sbjct: 242 DYYIG-GRRFSSLSDLIGYY-SYVSCLLKGE--KLLSPVA 277
Score = 49.2 bits (112), Expect = 1e-04
Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 3/83 (3%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNK 455
K W+HG ++ KEA +L+M G+ SFLVR S PG+Y L R + I +N+
Sbjct: 357 KVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKISPTSNNQ 416
Query: 456 YDVGSG--EQFDDLVGLIEHFRS 518
Y +G +++ + L HF+S
Sbjct: 417 YMMGGRYYNRYEPICMLGHHFQS 439
>UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant; n=9;
Tetrapoda|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant - Homo
sapiens (Human)
Length = 377
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/51 (49%), Positives = 34/51 (66%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
WFHG +S +EAE+L+ NG FLVRES PG+YVL+ G+ H+L+
Sbjct: 267 WFHGKLSRREAEALLQ---LNGDFLVRESTTTPGQYVLTGLQSGQPKHLLL 314
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/79 (31%), Positives = 49/79 (62%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W G ++ E ++L+++K + G+FLVR+S+ PG+ VL V +VSH +I R+ +++ +
Sbjct: 18 WHFGGITRSETDNLLIQK-RPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVI 76
Query: 465 GSGEQFDDLVGLIEHFRSY 521
G + F L ++ +R +
Sbjct: 77 GD-QIFSTLPDILNFYRGH 94
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 458
WFHG ++ + +E + + NG FLVR+ + G Y L + G+V H + R Q K
Sbjct: 163 WFHGAITREGSEPRLQNGSRINGRFLVRQRDTN-GSYALCLLHEGQVMHYRVDRDQAGKL 221
Query: 459 DVGSGEQFDDLVGLIEHFRSYP 524
+ G++FD L L+EH+ P
Sbjct: 222 SIPEGKKFDTLWQLVEHYSYKP 243
>UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Xenopus tropicalis|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Xenopus tropicalis
Length = 321
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S +A L+ +G G FLVR+S+ GEYVL+ +GR H+ +
Sbjct: 223 WFHGPISRVKAAQLVQSQGVEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLTLTERGQ 282
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+F ++ ++++FR P+
Sbjct: 283 CHVQHLRFRSVLEMLQYFRLQPI 305
>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA
- Drosophila melanogaster (Fruit fly)
Length = 1236
Score = 51.6 bits (118), Expect = 2e-05
Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Frame = +3
Query: 279 KKWFHGVMSA--KEAESLIMEKGK--NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 446
+ WFHG + KEA+ L+ + +G+FLVRES G+Y LS R R +H I+ +
Sbjct: 587 ENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLK 646
Query: 447 HN----KYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
H KY + FD L LI ++R M+ +S + L +PV
Sbjct: 647 HENGSIKYYLVENFVFDSLYSLIVYYRK-NMLRSSEFSIILKEPV 690
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/103 (28%), Positives = 51/103 (49%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
++WFH + ++AE + + GSFLVR S +V+S + ++ H I ++ Y
Sbjct: 699 QEWFHPNTTKEQAEQGLYRL-EIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLY 757
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLR 587
+ + F+ LV LI ++ P+ ++L PVS LR
Sbjct: 758 GIDT-MNFESLVSLINYYTRNPLYRN----VKLSHPVSQELLR 795
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/76 (36%), Positives = 40/76 (52%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 467
F G M EAE M + +G+FLVRES GEY LSVR R H+ I + + +
Sbjct: 661 FAGKMDRTEAEQETMGRS-DGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCLT 719
Query: 468 SGEQFDDLVGLIEHFR 515
+ FD + L+ ++R
Sbjct: 720 QSKVFDSIPELVAYYR 735
>UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|Rep:
MGC80721 protein - Xenopus laevis (African clawed frog)
Length = 508
Score = 51.2 bits (117), Expect = 3e-05
Identities = 33/97 (34%), Positives = 55/97 (56%), Gaps = 10/97 (10%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQ----AHPGEYVLSVRVRGRVSHVLIRRQ- 446
+W+ G +S EAE+ + ++G+FLVR S +HP YVL V R +V ++ IR+
Sbjct: 394 QWYTGNISRSEAETALRSINQDGTFLVRNSSKSTASHP--YVLMVLYRNKVYNIQIRQDQ 451
Query: 447 -HNKYDVGSG----EQFDDLVGLIEHFRSYPMIETSG 542
+N Y +GSG E F ++ +I++F P++ G
Sbjct: 452 TNNVYMLGSGLRGQETFASVMEIIDYFHKTPLLLIDG 488
>UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate
lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel
protein similar to vertebrate lymphocyte adaptor protein
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 279
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNG--SFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S A L+ G +G +FLVR+S+ G+YVL+ +GR H+ +
Sbjct: 119 WFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSLTEWGQ 178
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
+F ++ ++ HFR+ P+
Sbjct: 179 CRVQHLRFPSVMDMLSHFRNCPI 201
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/51 (45%), Positives = 36/51 (70%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
W+HG MS ++AE+L+ G++G FLVR+S +PG+YVL+ G H+L+
Sbjct: 406 WYHGRMSRRDAENLL---GRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLL 453
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 51.2 bits (117), Expect = 3e-05
Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Frame = +3
Query: 255 ELSKAFMLKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSV----RVRG- 416
E + + WF M+ KEAE + G + G+FL+R S+ PG Y LSV RG
Sbjct: 173 EPADVLQAEDWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGF 232
Query: 417 RVSHVLIRRQHNK-YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAH 593
V H IR N Y + + F L L+ H+ S + G V RLL P +
Sbjct: 233 NVKHYRIRTLDNDGYYISTRITFHTLHDLVNHYTS----QADGLVCRLLNPCPRQKPVMF 288
Query: 594 DIDQKVQEMQGIEDRQKMECNTGFDGE 674
+I + V E+ + + + G GE
Sbjct: 289 EISKDVWEIPRRSIKLERKLGNGQFGE 315
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 50.8 bits (116), Expect = 3e-05
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG +S EAES++ ++G FLVRESQ PG+YVL+ H+L+
Sbjct: 346 WFHGSVSRAEAESMLT---RDGDFLVRESQGSPGQYVLTGMNNNTPKHLLLIDPEGVVRT 402
Query: 465 GSGEQFDDLVGLIEHFRSYPMIETSGD-VLRLLQPV 569
FD + L+ H + S D VL L P+
Sbjct: 403 -KDRVFDSVSHLVNHHCDNVLPIISADSVLVLRYPI 437
>UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound
protein 7 (GRB7 adapter protein) (Epidermal growth
factor receptor GRB-7) (B47).; n=1; Takifugu
rubripes|Rep: Growth factor receptor-bound protein 7
(GRB7 adapter protein) (Epidermal growth factor receptor
GRB-7) (B47). - Takifugu rubripes
Length = 485
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +3
Query: 249 LKELSKAFMLKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVS 425
L L + + WFHG +S KEA+ LI ++G +G FL+RESQ H +VLS+ + ++
Sbjct: 372 LSSLVAVHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHGQCFVLSLSHQLKIK 431
Query: 426 HVLI 437
H L+
Sbjct: 432 HYLV 435
>UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG16480;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG16480 - Caenorhabditis
briggsae
Length = 487
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE---YVLSVRVRG---RVSHVLIRRQ 446
WFHG++ +E + L++ KNG FLVR S+ G+ +LSV H +IR
Sbjct: 67 WFHGLLPREEVQLLLL---KNGDFLVRMSEPSSGQARHLILSVMQNESSQEAMHYVIRNA 123
Query: 447 HNKYDVGSGEQFDDLVGLIEHFRSYPMIE 533
K+ + E FD L+ LI H + + E
Sbjct: 124 DGKFSITGKENFDSLIELINHHKQNKLHE 152
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
W+HG +S +AE+L + K S+LVR S+ ++ LS++ H+ L R ++NKY
Sbjct: 380 WYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKNNKYV 438
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
+G + F + ++ H+ S + + + LL PV+
Sbjct: 439 LGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVA 476
>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
n=13; Mammalia|Rep: SH2 domain-containing adapter
protein D - Homo sapiens (Human)
Length = 340
Score = 50.8 bits (116), Expect = 3e-05
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
WFHG ++ +AESL+ K GS+LVR S+ +P + LS+R H+ R + N+
Sbjct: 240 WFHGPLNRADAESLL-SLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQVV 298
Query: 462 VGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G F + L+ H+ S P+ + L LL PV
Sbjct: 299 LGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPV 335
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG +S +AE+L+ K S+LVR SQ +Y LS+R H+ + + KY +
Sbjct: 410 WYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVL 468
Query: 465 G-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
G + FD + +I ++ + + + L LL PV+
Sbjct: 469 GQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVA 505
>UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3;
Xenopus tropicalis|Rep: Putative uncharacterized protein
- Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 379
Score = 50.4 bits (115), Expect = 4e-05
Identities = 32/106 (30%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +3
Query: 258 LSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
L+ + W+HG +S EAE ++ K GSF++R Q EY +SVR H+ +
Sbjct: 272 LNPPLQTQVWYHGKLSKLEAEK-YLQNCKPGSFVIRIEQ--DIEYFMSVRGSHSTQHLKV 328
Query: 438 RRQHNKYDV--GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+ N++ + SG F ++ L+EH+ +P++ + + L L PV
Sbjct: 329 KCIENEHFMLGESGPSFTCILELVEHYMKHPLLLQNEEQLFLQCPV 374
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 50.4 bits (115), Expect = 4e-05
Identities = 32/104 (30%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN---- 452
W+ G MS ++A L++ + ++G FLVR+S G++VL VR +VSH +I + +
Sbjct: 12 WYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPSGDEC 71
Query: 453 -KYDVGSGEQFDDLVGLIEHFRSYPMIET--SGDVLRLLQPVSG 575
Y +G + F DL L+ ++ + + T ++R L+ V G
Sbjct: 72 FVYRIGD-QTFADLPDLLSFYKLHYLDTTPLRRPMVRRLEKVIG 114
>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
Protein vav-2 - Homo sapiens (Human)
Length = 878
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/84 (23%), Positives = 47/84 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF G M ++ ++L+ +G++L+RE A + +S++ V H+ + + N +
Sbjct: 673 WFAGNMERQQTDNLLKSHA-SGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHI 731
Query: 465 GSGEQFDDLVGLIEHFRSYPMIET 536
++FD L+ L+E+++ + + E+
Sbjct: 732 TEAKKFDSLLELVEYYQCHSLKES 755
>UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;
Theria|Rep: SH2 domain-containing protein 1B - Homo
sapiens (Human)
Length = 132
Score = 50.4 bits (115), Expect = 4e-05
Identities = 32/104 (30%), Positives = 59/104 (56%), Gaps = 6/104 (5%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 461
++HG ++ ++ E+L++++G +G+FL+R+S++ PG L V + V ++ + R +H Y
Sbjct: 5 YYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYR 64
Query: 462 V----GSGEQ-FDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGT 578
+ GS +Q F L LI F G V+ LL+P+ T
Sbjct: 65 IQTAEGSPKQVFPSLKELISKFEK----PNQGMVVHLLKPIKRT 104
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNKY 458
W+HG ++ + A +++ KG ++G FL+R+ P +YVLS+ R ++ H I NK+
Sbjct: 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69
Query: 459 DVGSGEQFDDLVGLIEHFR 515
+ +G F L LI +++
Sbjct: 70 SIDNGPIFQGLDMLISYYK 88
Score = 37.5 bits (83), Expect = 0.33
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN 452
+ +W H + A ++ +GSFL+R S G YVL++ + H I+ + +
Sbjct: 284 ITQWLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRAD 343
Query: 453 K-YDVGSGEQFDDLVGLIEHFRSY 521
+ + + G F+ L L++H+ Y
Sbjct: 344 RWFYIDDGPLFETLPHLVDHYMQY 367
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 50.4 bits (115), Expect = 4e-05
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--- 455
W+ G MS ++A ++M + + G FLVR+S + G+YVL VR +VS+ +I + +
Sbjct: 12 WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQI 71
Query: 456 -YDVGSGEQFDDLVGLIEHF 512
Y +G + FD+L L+ +
Sbjct: 72 VYRIGD-QSFDNLPKLLTFY 90
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 50.0 bits (114), Expect = 6e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
WFHG ++ +AESL + K GS+LVR S+ P + LS+R H+ R + N+
Sbjct: 121 WFHGPLNRADAESL-LSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVV 179
Query: 462 VGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G F + L+ H+ S P+ + L LL PV
Sbjct: 180 LGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPV 216
>UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 492
Score = 50.0 bits (114), Expect = 6e-05
Identities = 38/108 (35%), Positives = 53/108 (49%), Gaps = 18/108 (16%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIME----------KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 434
WFHG+M K AE L+++ + G FLVR+S G +V+SV R +H L
Sbjct: 69 WFHGLMERKVAEELLLKSPFRGHTSHPSSREGLFLVRQSSNRGGHFVISVCTRNHCNHYL 128
Query: 435 IR--------RQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLR 554
I R+ D G Q DL LI+ +R+ P+ E SG VL+
Sbjct: 129 IETIESMFYVRRDRSEDRGRDIQACDLRNLIQCYRTTPLDE-SGLVLK 175
>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 723
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = +3
Query: 213 AVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGE 389
A PA + + + + S +W+ G +S +E + + +G+FLVR++ + GE
Sbjct: 338 AKPAKSKVAPSAMTDTSSLLNDAEWYWGEISREEVNEKLRDT-PDGTFLVRDASSKLEGE 396
Query: 390 YVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQP 566
Y L++R G + I + +Y F +V LI H+R + + + + +LL P
Sbjct: 397 YTLTLRKGGNNKLIKIYHREGRYGFSEPLTFLSVVELINHYRHESLAQYNAKLDTKLLYP 456
Query: 567 VS 572
VS
Sbjct: 457 VS 458
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
W+ G + +AE ++ +G +G+FL+RESQ G Y SV V G H ++ + Y
Sbjct: 622 WYVGDIKRSQAEEML--RGTCDGTFLIRESQTQKGSYACSVVVDGDTKHCVVYKTVTGYG 679
Query: 462 VGSG-EQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPV 569
+ L L+ H+++ +++ + + + L PV
Sbjct: 680 FAEPYNLYSSLKDLVLHYKNVSLVQHNDHLNVTLAHPV 717
>UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2
SCAF14705, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 487
Score = 50.0 bits (114), Expect = 6e-05
Identities = 25/61 (40%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Frame = +3
Query: 258 LSKAFMLKKWFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVL 434
L+ + + WFHG +S KEA+ LI ++G +G FL+RESQ H +VLS+ + ++ H L
Sbjct: 359 LAALHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHAQCFVLSLCHKLKIKHYL 418
Query: 435 I 437
+
Sbjct: 419 V 419
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 50.0 bits (114), Expect = 6e-05
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Frame = +3
Query: 231 AIVSTVLKELSKAFM-LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 407
++ + V S +FM K W+HG +S EAE L+ ++G FLVRES++ PG+YVLS
Sbjct: 360 SVHAPVASTRSSSFMRAKDWYHGPISRGEAELLLEDEG---DFLVRESKSQPGQYVLSGI 416
Query: 408 VRGRVSHVLI 437
+ H+L+
Sbjct: 417 KDKQARHLLL 426
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 50.0 bits (114), Expect = 6e-05
Identities = 29/96 (30%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
WF G + +AE ++ ++ +G+FL+RES++ PG++ LSV+ V H ++R KY
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+ +F+ L L+++ RS + LR ++ V
Sbjct: 120 LWV-VKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV 154
>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
isoform A, partial; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to CG9098-PA, isoform A, partial -
Tribolium castaneum
Length = 851
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 8/134 (5%)
Frame = +3
Query: 66 NSRRETYPSFIKNILVEKT*VMSKDNPRLSRLGVLAPAALSACMDASVLAVPAAGAIVST 245
N RR+ PS ++ V+KT + ++ +LS L + S ++ ++ A ++ S
Sbjct: 98 NFRRQ--PSIRHSVAVDKT-ITIEETDKLSNLSSVYEPVQSKSLNNLIMEPTADPSMNSL 154
Query: 246 VLKEL--------SKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 401
LK+ S+ W+HG + AE ++ E+G FLVR+ + PG YVL+
Sbjct: 155 ELKKALEWELSLDSRDLRSHAWYHGAIPRSRAEDIVREEG---GFLVRDCTSQPGNYVLT 211
Query: 402 VRVRGRVSHVLIRR 443
R + + H +I +
Sbjct: 212 CRTKTQPLHFVINK 225
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIME---KGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQ 446
++W+HG ++ + A L+ + + G FLVRES PG YVL++ +G V ++
Sbjct: 8 ERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMGHG 67
Query: 447 HNKYDVGSGEQFDDLVGLIEHFRSYP 524
+ V +G F L LI H++ P
Sbjct: 68 EGWFSVDNGPLFQGLDELIHHYQLKP 93
Score = 37.9 bits (84), Expect = 0.25
Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKY 458
+ H + A + +KG +GSFL+R + PG Y L++ + H ++ Y
Sbjct: 292 FLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYEVVCESDCWY 351
Query: 459 DVGSGEQFDDLVGLIEHF 512
+ G FD L +++H+
Sbjct: 352 FIDDGPLFDTLPAVVDHY 369
>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
Protein vav-3 - Homo sapiens (Human)
Length = 847
Score = 49.6 bits (113), Expect = 8e-05
Identities = 20/88 (22%), Positives = 45/88 (51%)
Frame = +3
Query: 270 FMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 449
+ + W+ G M +AE+ ++ + N ++LVR GEY +S++ H+ I +
Sbjct: 667 YSCQPWYAGAMERLQAETELINR-VNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRD 725
Query: 450 NKYDVGSGEQFDDLVGLIEHFRSYPMIE 533
+ + +F L+ L+E+++ + + E
Sbjct: 726 GFFHIAENRKFKSLMELVEYYKHHSLKE 753
>UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Protein
SH(2)A); n=23; Euteleostomi|Rep: SH2 domain-containing
protein 4A (Protein SH(2)A) - Homo sapiens (Human)
Length = 454
Score = 49.6 bits (113), Expect = 8e-05
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 461
WFHG+++ K+A L++ G GSFL+R S+ G Y LS H LI + Y
Sbjct: 347 WFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLSEDGCKHFLIDASADAYSF 405
Query: 462 VGSGE-QFDDLVGLIEHFRSYPMIETSGDVL 551
+G + Q L L+E+ + P+ ++L
Sbjct: 406 LGVDQLQHATLADLVEYHKEEPITSLGKELL 436
>UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 936
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/79 (27%), Positives = 44/79 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W++G M +E E L++ +GK+ +LVR+S G+ +LSV +V H +I+ +K
Sbjct: 836 WYYGRMLRQECEYLMLSQGKSKQYLVRDSSHRAGDLMLSVLYGSKVHHYVIQTTDDKKFQ 895
Query: 465 GSGEQFDDLVGLIEHFRSY 521
+ FD + +++ + +
Sbjct: 896 IAHHDFDSVEAILDFYHKH 914
>UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2 domain containing 4B -
Strongylocentrotus purpuratus
Length = 470
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG+++ ++AE L+ K + G FLVR S G Y LS R + R H LI + Y
Sbjct: 355 WFHGIITRQQAEYLLFPKAE-GHFLVRVSNRIWG-YALSFRDKERAKHFLIDASGSMYSF 412
Query: 465 GSGEQFD--DLVGLIEHFRSYPMIETSGDVLR 554
+Q D L L++ P+ E +VL+
Sbjct: 413 FGQDQKDHASLEDLVQFHMRMPISEMGKEVLK 444
>UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Bos taurus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Bos Taurus
Length = 526
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S +A L+ +G + G FLVR+S+ GEYVL+ +G H+ +
Sbjct: 428 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERGQ 487
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
F +V ++ HF+ P+
Sbjct: 488 CRVQHLHFPSVVDMLHHFQRSPI 510
>UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 636
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 12/98 (12%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S A L++ G +G F++R+S+ PGEYVL+ +G+ + V RR + +
Sbjct: 411 WFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGK-AKVRQRRAESTF 469
Query: 459 DVGSGEQFDDLVG----------LIEHFRSYPMIETSG 542
V +G + L+ HF ++P+ SG
Sbjct: 470 AVVAGTRTGSATSTTCGSTPCRTLLRHFHAHPIPLESG 507
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
WF G + +AE ++ ++ +G+FL+RES++ PG++ LSV+ V H ++R KY
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 462 VGSGEQFDDLVGLIEHFRS 518
+ +F+ L L+++ RS
Sbjct: 120 LWV-VKFNSLNELVDYHRS 137
>UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 250
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/98 (26%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+ G S KEA + M ++G+F+VR+S+ PGEY L++ G + + I + KY
Sbjct: 5 EWYWGEAS-KEAVNARMRDTEDGTFIVRDSKRFPGEYTLTLMKGGVIKLIRIMYKDGKYG 63
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPVS 572
F ++ L+ +++ + + + + ++L P+S
Sbjct: 64 FSEPLTFKSVIDLVSYYKDRSLAQYNPKLDVKLAHPLS 101
>UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15;
Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens
(Human)
Length = 575
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKN--GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
WFHG +S +A L+ +G + G FLVR+S+ GEYVL+ +G H+ +
Sbjct: 364 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERGQ 423
Query: 459 DVGSGEQFDDLVGLIEHFRSYPM 527
F +V ++ HF+ P+
Sbjct: 424 CRVQHLHFPSVVDMLHHFQRSPI 446
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 458
WFHG ++ EAE+ ++ + GSFLVR S++ +Y LS++ H+ I++ N Y
Sbjct: 770 WFHGAITRVEAEN-VLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDGNDECY 828
Query: 459 DVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G + F + +I HF + + + LLQPV
Sbjct: 829 ILGQFSKPFHSIPEMIRHFCINRLPIRGAEHMCLLQPV 866
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/90 (30%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Frame = +3
Query: 246 VLKELSKAFMLKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQAHPGEYVLSVRVRGRV 422
V+K+L +L+ W+H + EAES + +G ++G+FLVR + YVLS+ +
Sbjct: 192 VIKDLH---LLQPWYHHTIRRYEAESRLASEGNQDGAFLVRYRK-EDRTYVLSLTSQNEP 247
Query: 423 SHVLIRRQHNKYDVGSGEQFDDLVGLIEHF 512
H I +++ + G+ F+ ++ LI+H+
Sbjct: 248 KHYRIEEYLSRWSIEGGQYFETIMELIDHY 277
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQHNK 455
++WF +S AE+++ +G+ G F+VR S + Y LS+ G+V H I+ + NK
Sbjct: 316 EEWFFPQLSRTRAENILKGEGREGGFVVRNS-SRENMYTLSICHEGQVRHYHIKLDESNK 374
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
Y + +F + LIE Y + G V RL +P
Sbjct: 375 YFISEKHRFPSIKELIE----YHKLNGGGLVTRLRKP 407
>UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae
str. PEST
Length = 397
Score = 48.8 bits (111), Expect = 1e-04
Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
Frame = +3
Query: 219 PAAGAIVSTVLKELSKAFMLK--KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEY 392
P G ++ +++ + + L+ +W+ G +S A+ +M+ +GSFLVR++ GE+
Sbjct: 118 PNGGGMLMSLITDPNTPQELRDAEWYWGKISRDVAKEKMMD-APDGSFLVRDAINDAGEF 176
Query: 393 VLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPV 569
L ++ G + I ++ KY F+ LVG+I FR+ + E + + + LL P+
Sbjct: 177 TLVLKKDGTDRPIKIYHKNGKYGFTQECTFESLVGMINEFRTTTLKEYNTILDISLLYPI 236
Query: 570 S 572
S
Sbjct: 237 S 237
>UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 681
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/68 (35%), Positives = 40/68 (58%)
Frame = +3
Query: 330 MEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEH 509
M G GSF++R S PG+Y LS+R + V+ LIRRQ +Y +G G F + +++
Sbjct: 1 MRDGAVGSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMG-GRVFCSIDDVVKR 59
Query: 510 FRSYPMIE 533
++ ++E
Sbjct: 60 YKHEHIVE 67
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/73 (36%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +3
Query: 228 GAIVSTVLKELSKAFMLKKWFHGVMSAKEAES-LIMEKGKNGSFLVRESQAHPGEYVLSV 404
G I S + E ++ + WF G + +AE L+ + K GSFL+RES++ GE+ LSV
Sbjct: 98 GYIPSNYVAE-DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSV 156
Query: 405 RVRGRVSHVLIRR 443
V H I+R
Sbjct: 157 LDGAVVKHYRIKR 169
>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14679, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 283
Score = 48.4 bits (110), Expect = 2e-04
Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKY 458
+WF S AE L+ KG G F++R Q+ PGE+ +SVR V H ++R +Y
Sbjct: 57 RWFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQY 115
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIET 536
+ S E+F L L++ +R+ + +T
Sbjct: 116 FLWS-EKFTSLNKLVDFYRTSSISKT 140
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
W+HG +S +AE+L + K S+LVR S+ ++ LS++ H+ L R + +KY
Sbjct: 346 WYHGAISRTDAENL-LRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYV 404
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVS 572
+G + F + ++ H+ S + + + LL PV+
Sbjct: 405 LGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVA 442
>UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Grb2 adaptor protein -
Strongylocentrotus purpuratus
Length = 532
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/41 (48%), Positives = 28/41 (68%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 407
WF G +S +AE ++ +G L+RES+AHPG+Y LSVR
Sbjct: 206 WFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLSVR 246
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG +S +EA L+ K G FLVR S A Y L+V++ G + H +I QHN+
Sbjct: 517 WYHGEISRQEATGLLK---KMGDFLVRYS-ADKEHYTLTVKMEG-IKHFII--QHNEEGF 569
Query: 465 G-SGEQFDDLVGLIE-HFRS-YPMIETSGDVLRLLQPVSGTRLRAHDI 599
G+ + + LI+ HF++ P+ S +LR QPV LR ++I
Sbjct: 570 RFEGDPYPSIPMLIDHHFKNRLPVTRKSQAILR--QPVKKPDLREYNI 615
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS-VRVRGRVSHVLIRRQHNKYD 461
WFHG +S E+E+ + +K + G+FLVR S + G Y +S V G +SH I R K+
Sbjct: 424 WFHGDISTSESENRLRQKPE-GTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQ 482
Query: 462 VGSGE 476
V + +
Sbjct: 483 VNNSK 487
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/78 (33%), Positives = 43/78 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF G +S AE+ + ++ GSFLVRES++ PGE+ +SV V H + + Y
Sbjct: 60 WFAGRISRHVAENRLHQRDC-GSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDREGYYF 118
Query: 465 GSGEQFDDLVGLIEHFRS 518
E F L L++++++
Sbjct: 119 VWEEIFPSLNQLVDYYKT 136
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 47.2 bits (107), Expect = 4e-04
Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Frame = +3
Query: 201 ASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQA 377
A L G I S + E + ++WF+ ++ K+AE L+ K GS+L+RES+
Sbjct: 100 ARSLTTRKEGFIPSNYVAE-ADTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESET 158
Query: 378 HPGEYVLSVR---VRGR--VSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHF 512
G Y LS+R +G+ V H IR N Y + F D+ +I+H+
Sbjct: 159 SKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSMIKHY 209
>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 47.2 bits (107), Expect = 4e-04
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRVSHVLIRRQHNK 455
K W+HG +S ++A++L+ +G FLVR+S PG+YVLS R H+++ HN+
Sbjct: 209 KVWYHGNLSREDAQALLKTEG---DFLVRQSDHTPGKYVLSGRTAENEHKHLILLDNHNR 265
Query: 456 YDVGSGEQFDDLVGLIE-HFRSYPMIETSG----DVLRLLQPV 569
F ++ LI+ H + + + G L L++PV
Sbjct: 266 VRT-RDRTFSNISELIDYHVNNGMAVRSEGRDRETSLNLIRPV 307
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH--NKY 458
W+HG +S +AE ++ G+ GSFLVR S++ +Y L+++ H+ I+R H ++
Sbjct: 943 WYHGSISRIDAEKILRPLGE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDHETGQF 1001
Query: 459 DVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G F + +I HF + + + LL+PV
Sbjct: 1002 ILGQFSRPFPTIPDMIRHFCLNRLPVRGAEHMCLLEPV 1039
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 47.2 bits (107), Expect = 4e-04
Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSV------RVRGRVSHVLIR-R 443
WF G +S ++E L+ +KGK G+F+VR S + G Y +S+ +G V H +
Sbjct: 296 WFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTVKHYHVHTN 354
Query: 444 QHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKVQEMQ 623
NK + FD + LI H+ + ++G + RL PVS +A+ + V
Sbjct: 355 AENKLYLAENYCFDSIPKLI-HYHQH---NSAGMITRLRHPVS---TKANKVPDSVSLGN 407
Query: 624 GIEDRQKME 650
GI + ++ E
Sbjct: 408 GIWELKREE 416
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 46.8 bits (106), Expect = 5e-04
Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH--NKY 458
W+HG ++ EAE+ ++ + GS+LVR S++ +Y LS++ H+ I++ N Y
Sbjct: 1081 WYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAY 1139
Query: 459 DVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G + FD + ++ HF + + + LL PV
Sbjct: 1140 ILGQFSKPFDSIPEMVRHFSINRLPIRGAEHMCLLHPV 1177
>UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adaptor
protein 2, partial; n=1; Pan troglodytes|Rep: PREDICTED:
similar to SH2B adaptor protein 2, partial - Pan
troglodytes
Length = 178
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/47 (40%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKG--KNGSFLVRESQAHPGEYVLSVRVRGR 419
WFHG +S +A L++ G +G F++R+S+ PGEYVL+ +G+
Sbjct: 130 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGK 176
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 46.8 bits (106), Expect = 5e-04
Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH--NKY 458
W+HG ++ EAE+ ++ + GS+LVR S++ +Y LS++ H+ I++ N Y
Sbjct: 1021 WYHGSITRIEAEA-VLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAY 1079
Query: 459 DVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G + FD + ++ HF + + + LL PV
Sbjct: 1080 ILGQFSKPFDSIPEMVRHFSVNRLPIRGAEHMCLLHPV 1117
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/51 (43%), Positives = 36/51 (70%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
W+ G +S +A SL+ + ++G+FLVR+S + PG++VLSV RVSH ++
Sbjct: 248 WYWGRLSRGDAVSLLQGQ-RHGTFLVRDSGSIPGDFVLSVSESSRVSHYIV 297
>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
receptor-bound protein 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Growth factor
receptor-bound protein 2 - Strongylocentrotus purpuratus
Length = 176
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
WF ++ K AE L+M++ +NG+FLVR S++ G Y LSV+ V H +++ K+
Sbjct: 14 WFFPTITRKNAELLLMQE-RNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAGKFH 72
Query: 462 VGSGEQFDDLVGLIEHFRS 518
+ +F L L++++R+
Sbjct: 73 LWI-VKFPSLDALVDYYRT 90
>UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X).; n=1; Takifugu
rubripes|Rep: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X). - Takifugu rubripes
Length = 266
Score = 46.4 bits (105), Expect = 7e-04
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK--Y 458
WFHG+++ K AE L+ + + G FL+R S++ G Y LS R R H +I +
Sbjct: 23 WFHGIITRKAAEELLAPRPR-GCFLIRVSESRAG-YTLSYRAEDRCKHFMIDVMEDGCFI 80
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRL 557
VG + L L++ R P I S +VL L
Sbjct: 81 IVGEKRRHQFLQDLVDFHRHTP-ITPSTEVLTL 112
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKY 458
+W+ G + EAE + G + GSFLVR S++ EY LSVR V H IR ++++
Sbjct: 221 EWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYRIRSRYSRT 280
Query: 459 D 461
D
Sbjct: 281 D 281
>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein plc-3 - Caenorhabditis elegans
Length = 1299
Score = 46.4 bits (105), Expect = 7e-04
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIME-KGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--- 443
++WFHG EA+ I+E K K NG F++R+S G++ LS+ G+V HV IR
Sbjct: 552 EEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKII 611
Query: 444 -QHNKYDVGSGEQFDDLVGLIEHF 512
+ KY + D L L+ ++
Sbjct: 612 DKEKKYYFMDNKVCDTLYELVSYY 635
Score = 42.7 bits (96), Expect = 0.009
Identities = 22/76 (28%), Positives = 40/76 (52%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF ++AE L+ ++G+FL+R S YVLS++V G H ++R + V
Sbjct: 664 WFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIFVV 723
Query: 465 GSGEQFDDLVGLIEHF 512
+ F++L ++E +
Sbjct: 724 NQ-KVFENLNQIVEFY 738
>UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing
protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2
domain-containing protein homolog - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 365
Score = 46.4 bits (105), Expect = 7e-04
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 2/88 (2%)
Frame = +3
Query: 273 MLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR-RQH 449
++ +WFHG++S K AE ++M K G FL+R S++ G Y LS R R H +I
Sbjct: 30 VVPEWFHGIISRKAAEEMLMCK-PAGYFLIRVSESRVG-YTLSYRAEDRCRHFMINVLPD 87
Query: 450 NKY-DVGSGEQFDDLVGLIEHFRSYPMI 530
N++ VG + L L+ R P++
Sbjct: 88 NQFMIVGEKTVYCSLHDLVAFHRRCPIL 115
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/104 (29%), Positives = 54/104 (51%)
Frame = +3
Query: 204 SVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP 383
S + A G++V EL A W+ G +S +EA+S++ K +GSFLVR++ +
Sbjct: 9 STMRPQAPGSLVDPNEDELRMA----PWYWGRISREEAKSILHGK-PDGSFLVRDALSMK 63
Query: 384 GEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFR 515
GEY L++ G + I KY + F+ +V +I +++
Sbjct: 64 GEYTLTLMKDGCEKLIKICHMDRKYGFIETDLFNSVVEMINYYK 107
>UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:
B-cell linker protein - Homo sapiens (Human)
Length = 433
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/105 (26%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Frame = +3
Query: 240 STVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVR 413
++ + E + K W+ G K AE + K+GSFL+R+S H + Y L+V
Sbjct: 308 NSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLAVFFN 367
Query: 414 GRVSHVLIR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 530
RV ++ +R +Y +G +GE+ F + +I + + P++
Sbjct: 368 KRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 412
>UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 1; n=39; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- Homo sapiens (Human)
Length = 1189
Score = 46.0 bits (104), Expect = 0.001
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 6/105 (5%)
Frame = +3
Query: 273 MLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQH 449
M+ W HG ++ +AE L+ GK+GSFLVR S++ Y L V R V ++ ++ +
Sbjct: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
Query: 450 NKYDVGSGEQ-----FDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+K+ V + E F L LIE ++ E G V L PV
Sbjct: 61 DKFTVQASEGVSMRFFTKLDQLIEFYKK----ENMGLVTHLQYPV 101
>UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4;
Murinae|Rep: SH2 domain-containing protein 4A - Mus
musculus (Mouse)
Length = 421
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 461
WFHG+++ K+A L + G GSFL+R S+ G Y LS H LI N Y
Sbjct: 315 WFHGILTLKKANEL-LSTGVPGSFLIRVSEKIKG-YALSYLSEEGCKHFLIDASANSYSF 372
Query: 462 VGSGE-QFDDLVGLIEHFRSYPMIETSGDVL 551
+G + Q L L+E+ + P+ ++L
Sbjct: 373 LGVDQLQHATLADLVEYHKEEPITSLGKELL 403
>UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Danio rerio|Rep: PREDICTED:
similar to Src-like-adaptor 2 - Danio rerio
Length = 193
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 6/83 (7%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRVRG----RVSHVLIRRQ 446
+WF +S + AE L+M + +G FL+RESQ+ PG Y LSVR V H I +
Sbjct: 28 RWFFEGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVRQHSGQMHTVLHYKIYQL 87
Query: 447 HNK-YDVGSGEQFDDLVGLIEHF 512
HN + + F L L++++
Sbjct: 88 HNGWFYIQPNHPFSTLSQLVDYY 110
>UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2
domain-containing molecule EAT2; n=1; Gallus gallus|Rep:
PREDICTED: similar to SH2 domain-containing molecule
EAT2 - Gallus gallus
Length = 134
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 461
+FHG +S K E L+ +KGKNGS+L+RES+ G L V + ++ + R Y
Sbjct: 5 FFHGKISRKACEDLLCKKGKNGSYLIRESETVAGALCLCVLFEKVIYTYRIFREYEGCYK 64
Query: 462 VGSGE 476
V + E
Sbjct: 65 VQTSE 69
>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 222
Score = 45.6 bits (103), Expect = 0.001
Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Frame = +3
Query: 201 ASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKG-KNGSFLVRESQA 377
A L G I ST + ++ +++WF M+ ++ E L++ G K GSFLVRES+
Sbjct: 77 AKSLVTGYEGFIPSTYVAR-AQTLQVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESET 135
Query: 378 HPGEYVLSVR----VRGR-VSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHF 512
G + LS+R +G V H IR N Y + F L L++++
Sbjct: 136 TKGAFSLSIRDSTPEQGDVVKHYKIRALDNGGYYISPSTSFSSLQELVKYY 186
>UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E;
n=16; Euteleostomi|Rep: SH2 domain-containing adapter
protein E - Homo sapiens (Human)
Length = 495
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKYD 461
W+HG +S EAES ++ K +LVR S++ Y ++++ H+++ + + NKY
Sbjct: 395 WYHGAISRAEAESR-LQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKYT 453
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSG-DVLRLLQPV 569
+ D + + H+ S + G + + LL PV
Sbjct: 454 LNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLLYPV 490
>UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15;
Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens
(Human)
Length = 551
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/51 (41%), Positives = 33/51 (64%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
W+HG MS + AE ++ +G FLVR+S +PG+YVL+ G+ H+L+
Sbjct: 456 WYHGRMSRRAAERMLRA---DGDFLVRDSVTNPGQYVLTGMHAGQPKHLLL 503
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG + + +E+L+ +NG FL+R+S G+YVL+ R R + H I NK V
Sbjct: 220 WYHGRIPREVSETLVQ---RNGDFLIRDSLTSLGDYVLTCRWRNQALHFKI----NKVVV 272
Query: 465 GSGEQFDDLVGLIE 506
+GE + + L E
Sbjct: 273 KAGESYTHIQYLFE 286
>UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing
protein; n=72; Eumetazoa|Rep: Hematopoietic SH2
domain-containing protein - Homo sapiens (Human)
Length = 352
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/53 (39%), Positives = 34/53 (64%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 440
+WFHG +S ++AE+L +E GSFL+R S +H G Y LS + + H +++
Sbjct: 33 EWFHGAISREDAENL-LESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVK 83
>UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar
to SH2 domain containing 4B - Danio rerio
Length = 266
Score = 45.2 bits (102), Expect = 0.002
Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFHG++S +++E+L+M GSFLVR S+ G Y LS R H LI + Y
Sbjct: 160 WFHGIISREDSETLLMNAAV-GSFLVRVSERIWG-YTLSYRTASGFKHFLIDASGDYYSF 217
Query: 465 GSGEQ--FDDLVGLIEHFRSYPMIETSGDVLRL 557
+Q L LI+ F +I T+G L L
Sbjct: 218 LGVDQNRHATLADLID-FHKEEIITTTGKELLL 249
>UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell
linker; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to B-cell linker - Strongylocentrotus
purpuratus
Length = 591
Score = 45.2 bits (102), Expect = 0.002
Identities = 30/89 (33%), Positives = 51/89 (57%), Gaps = 7/89 (7%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRES-QAHPGE-YVLSVRVRGRVSHVLIR-RQHNK 455
W++G + +E+E + + K+G+F+VR S + P Y L++ GRV ++ IR R+ +
Sbjct: 486 WYNGGIGRQESEKYLHQCRKDGAFIVRNSTRGDPANPYSLALWFNGRVRNLQIRKRKDQR 545
Query: 456 YDVGSGEQ----FDDLVGLIEHFRSYPMI 530
Y +GS + FD V LIEH + +I
Sbjct: 546 YALGSRKDNELAFDTPVQLIEHHMTNSLI 574
>UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep:
Zgc:101809 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/88 (27%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIRRQHNKY 458
W+ G ++ EAES + ++G+FLVR+S Y L V + +V ++ IRR +++
Sbjct: 391 WYLGQITRGEAESCLRRVNRDGTFLVRDSSNRSSNQPYTLVVLYQDKVYNIQIRRNQDRF 450
Query: 459 DVGSG----EQFDDLVGLIEHFRSYPMI 530
+G+G E F+ + ++ + P++
Sbjct: 451 MLGTGMKASESFERVSDIVNQHKHTPLL 478
>UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b); n=17;
Eutheria|Rep: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b) - Homo
sapiens (Human)
Length = 402
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/110 (25%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Frame = +3
Query: 249 LKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVS 425
+K+ S + +W+ G +S +E + + +G+FLVR++ G+Y L++R G
Sbjct: 53 MKDSSVSLQDAEWYWGDISREEVNDKLRDM-PDGTFLVRDASTKMQGDYTLTLRKGGNNK 111
Query: 426 HVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPVS 572
+ I + KY F+ +V LI H+ + + + + ++L+ PVS
Sbjct: 112 LIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVS 161
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 45.2 bits (102), Expect = 0.002
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Frame = +3
Query: 228 GAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 407
G I S + E + + +W+ M+ +AE L+ ++GK G F+VR+S + G+Y +SV
Sbjct: 262 GYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVF 320
Query: 408 VR------GRVSH-VLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
+ G + H V+ ++Y + F + LI +Y ++G + RL P
Sbjct: 321 AKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELI----NYHQHNSAGLISRLKYP 376
Query: 567 VS 572
VS
Sbjct: 377 VS 378
>UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91868
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 201
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 1/81 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
++ G M+ +EA L ++K G+FL+R+S+ + LS + + + I +++K+ +
Sbjct: 69 FYWGPMTVEEAH-LKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRINFKNSKFSL 127
Query: 465 -GSGEQFDDLVGLIEHFRSYP 524
GS E FD L L+EH+ S P
Sbjct: 128 TGSKESFDSLFKLLEHYISSP 148
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/38 (47%), Positives = 27/38 (71%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 398
W+H +S +AE L+ GK+GS+LVR+S++ PG Y L
Sbjct: 14 WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYAL 51
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/95 (28%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHV-LIRRQHNKYD 461
W++G ++ +AE L+ K + G+FL+R S++ PG++ LSV+ V H ++R K+
Sbjct: 34 WYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKFF 92
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQP 566
+ +F+ L L+++ R+ + + LR + P
Sbjct: 93 LWV-VKFNSLNELVDYHRTASVSRSQDVKLRDMVP 126
>UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein kin-14 - Caenorhabditis elegans
Length = 418
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLIRRQ--HN 452
+WFHGV+ ++A+ L++ K GSFL+R S+ H +LSVR G++ ++ + N
Sbjct: 29 EWFHGVLQRQDADELLV---KPGSFLLRASEVHGKMSMILSVRHDGKLHNIAVNSDTGEN 85
Query: 453 KYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLR 554
+ G E+ D + S P+ +TSG L+
Sbjct: 86 FWFEGHREKSIDQLVQWHMTTSTPITKTSGVKLK 119
>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 724
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/53 (33%), Positives = 32/53 (60%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + + AE ++ ++G FLVR+ + PG YVL+ + +G H +I +
Sbjct: 25 WYHGPIPRQRAEEIVQ---RDGDFLVRDCVSQPGNYVLTCKTKGPTLHFVINK 74
>UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;
Eutheria|Rep: SH2 domain-containing protein 3A - Homo
sapiens (Human)
Length = 576
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/53 (41%), Positives = 33/53 (62%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG++S ++AE+L+ + NG FLVR S + G V+S R RG H + R
Sbjct: 15 WYHGLLSRQKAEALLQQ---NGDFLVRASGSRGGNPVISCRWRGSALHFEVFR 64
>UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31;
Amniota|Rep: Lymphocyte cytosolic protein 2 - Homo
sapiens (Human)
Length = 533
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/96 (29%), Positives = 53/96 (55%), Gaps = 8/96 (8%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRES--QAHPGEYVLSVRVRGRVSHVLIRRQHN 452
++W+ ++ EAE+ + + ++G+FLVR+S + YVL V + +V ++ IR Q
Sbjct: 420 EEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKE 479
Query: 453 K--YDVGSG----EQFDDLVGLIEHFRSYPMIETSG 542
Y +G+G E F + +I++FR P++ G
Sbjct: 480 SQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDG 515
>UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|Rep:
B-cell linker protein - Homo sapiens (Human)
Length = 456
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Frame = +3
Query: 240 STVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVR 413
++ + E + K W+ G K AE + K+GSFL+R+S H + Y L V
Sbjct: 331 NSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFN 390
Query: 414 GRVSHVLIR--RQHNKYDVG---SGEQ-FDDLVGLIEHFRSYPMI 530
RV ++ +R +Y +G +GE+ F + +I + + P++
Sbjct: 391 KRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLV 435
>UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
LD41184p - Nasonia vitripennis
Length = 858
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + E +G FLVR+ + PG YVLSVR +G+ H +I +
Sbjct: 168 WYHGSSLPGGRKGAEAEIPNDGDFLVRDCSSQPGNYVLSVRHKGQALHFVINK 220
>UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to Src-like-adaptor 2 - Monodelphis
domestica
Length = 310
Score = 44.4 bits (100), Expect = 0.003
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIM-EKGKNGSFLVRESQAHPGEYVLSVRV-----RGRVSHVLIRRQ 446
W + ++ ++AE L++ GSFL+RESQ G Y LSVR+ R V H I R
Sbjct: 134 WLYEGLNREKAEDLLLLPSNHGGSFLIRESQTRRGAYSLSVRLSRPTSRDVVRHYRIHRL 193
Query: 447 HNK-YDVGSGEQFDDLVGLIEHF 512
N + + F L L+EH+
Sbjct: 194 ENGWFYISPRLTFPSLQALVEHY 216
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHN-KYD 461
W+HG ++ EAESL + K S+LVR+SQ +Y LS+R H+ + + K+
Sbjct: 221 WYHGALTRSEAESL-LTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMKFSQSRDGKFI 279
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G + FD + +I + + + + L LL PV
Sbjct: 280 LGENSPPFDSIPEVIHFYTTNKLPIRGAEHLSLLFPV 316
>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor Grb2 -
Strongylocentrotus purpuratus
Length = 241
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHP--GEYVLSVRVRGRVSHVLI 437
W+ G +S K AE +M +G+F++R+S+++P G + LSV+ R +V H I
Sbjct: 62 WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKI 114
>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
(Novel SH2-containing protein 3).; n=1; Takifugu
rubripes|Rep: SH2 domain-containing protein 3C (Novel
SH2-containing protein 3). - Takifugu rubripes
Length = 580
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/53 (37%), Positives = 36/53 (67%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + + AESL++ +G FL+R+S+++ G++VL+ + + H LIRR
Sbjct: 36 WYHGPVPWEVAESLVVN---HGEFLIRDSRSNHGDFVLTCHWQQKTLHFLIRR 85
>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14724,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 803
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/54 (35%), Positives = 33/54 (61%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 446
W+HG + + AE+L+ ++G FL+R+S + PG YVL+ + R H I ++
Sbjct: 36 WYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKK 86
>UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15009, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 466
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKN-GSFLVRESQAHPGEYVLSVRVRGR----VSHVLIRRQH 449
WF +S EA +M G GSFLVRES+ PG Y LS+R V H IR
Sbjct: 116 WFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKHYRIRNMD 175
Query: 450 N-KYDVGSGEQFDDLVGLIEHF 512
N + + + F+ L L++H+
Sbjct: 176 NGGFYITTKISFNSLKELVQHY 197
>UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit beta; n=114; Euteleostomi|Rep:
Phosphatidylinositol 3-kinase regulatory subunit beta -
Homo sapiens (Human)
Length = 728
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAH-PGEYVLSVRVRGRVSHVLIRRQHNKY 458
+W+ G +S +E + + +G+FLVR++ + GEY L++R G + + + Y
Sbjct: 329 EWYWGDISREEVNEKLRDT-PDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHY 387
Query: 459 DVGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPVS 572
F +V LI H+R + + + + RLL PVS
Sbjct: 388 GFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVS 426
>UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 391
Score = 44.0 bits (99), Expect = 0.004
Identities = 28/85 (32%), Positives = 42/85 (49%)
Frame = +3
Query: 255 ELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVL 434
ELSK + W+ G MS EAE + + +GSFLVR+S LS + GR H
Sbjct: 235 ELSK-LPRQPWYWGPMSQDEAEGKL-DDADDGSFLVRDSSDDRYLLTLSFKSNGRTLHTR 292
Query: 435 IRRQHNKYDVGSGEQFDDLVGLIEH 509
I ++ + + E ++ LIE+
Sbjct: 293 IEHRNGLFSLNDSEGHASVIELIEN 317
>UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p -
Drosophila melanogaster (Fruit fly)
Length = 421
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV---RGRVSHVLIRRQHNK 455
WF + +E + + G+FLVR+S PG + LS+RV RV+H LI R
Sbjct: 286 WFQAGIP-REISLEALSRQSPGAFLVRQSSTKPGCFALSLRVPPPSPRVAHYLILRTQRG 344
Query: 456 YDV-GSGEQFDDLVGLIEHFRSYP 524
Y + G ++F L LI H P
Sbjct: 345 YKIKGFTKEFSSLKALITHHSVMP 368
>UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to
ENSANGP00000021630; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021630 - Nasonia
vitripennis
Length = 389
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRV-----RGRVSHVLIRRQH 449
WF + +E ++ + G+F+VRES + PG Y LS+RV ++H LI R +
Sbjct: 256 WFQAGIP-REITLEVLSQEPEGAFMVRESTSKPGCYALSLRVPREFQPSGIAHYLIMRTN 314
Query: 450 NKYDV-GSGEQFDDLVGLIEHFRSYP 524
Y + G ++F L LI H P
Sbjct: 315 KGYKIKGFTKEFTTLTALITHHSVMP 340
>UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VIIa;
n=3; Gallus gallus|Rep: PREDICTED: similar to
Myosin-VIIa - Gallus gallus
Length = 918
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/56 (48%), Positives = 34/56 (60%)
Frame = +3
Query: 309 KEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGE 476
KEAE+L+++K G FLVR SQ+ PG Y L+ R GR H +I Q N V GE
Sbjct: 711 KEAENLLIDKPL-GCFLVRISQSRPG-YTLTYRGEGRCRHYMIEMQPNARYVILGE 764
>UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,
isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG9098-PA, isoform A - Apis mellifera
Length = 797
Score = 43.6 bits (98), Expect = 0.005
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + E +G FLVR+ + PG YVL+VR +G+ H +I R
Sbjct: 148 WYHGSTLRGGRKGAEAEVPNDGDFLVRDCASQPGNYVLTVRWKGQPLHFVINR 200
>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
Xenopus tropicalis
Length = 419
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/51 (41%), Positives = 32/51 (62%)
Frame = +3
Query: 249 LKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 401
LK S+ W+HG + ++AE L++ NG FL+R+S + PG+YVLS
Sbjct: 3 LKLSSEDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 50
>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
Xenopus tropicalis
Length = 514
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/51 (41%), Positives = 32/51 (62%)
Frame = +3
Query: 249 LKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 401
LK S+ W+HG + ++AE L++ NG FL+R+S + PG+YVLS
Sbjct: 16 LKLSSEDLRSHAWYHGPLPRQDAERLLVS---NGDFLIRDSISSPGDYVLS 63
>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
CG9098-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 944
Score = 43.6 bits (98), Expect = 0.005
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + + AE ++ + G FLVR+ + P YVLS R + V H ++ +
Sbjct: 240 WYHGALPRQRAEEIVQ---REGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNK 289
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEY---VLSVRVRGRVSHV-LIRRQHN 452
WF G ++ ++AE L+ + + G FLVRES PG+Y V+S + +V H +I N
Sbjct: 92 WFFGKITREKAEELLTPR-EVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRVISTSDN 150
Query: 453 KYDVGSGEQFDDLVGLIEHF 512
+ V F L+ LI+H+
Sbjct: 151 QVTVDEEAFFPTLIELIKHY 170
>UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=27;
Euteleostomi|Rep: Suppressor of cytokine signaling 6 -
Homo sapiens (Human)
Length = 535
Score = 43.6 bits (98), Expect = 0.005
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Frame = +3
Query: 213 AVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEY 392
+V ++G +V T L E K + W+ G ++ EAE + +GSFLVR+S
Sbjct: 360 SVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANV-PDGSFLVRDSSDDRYLL 418
Query: 393 VLSVRVRGRVSHVLIRRQHNK---YDVGSGEQFDDLVGLIEH 509
LS R G+ H I + + Y+ E +V LIEH
Sbjct: 419 SLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEH 460
>UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling
inositol polyphosphate 5 phosphatase SIP-145; n=1; Pan
troglodytes|Rep: PREDICTED: similar to signaling
inositol polyphosphate 5 phosphatase SIP-145 - Pan
troglodytes
Length = 177
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +3
Query: 273 MLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQH 449
M+ W HG ++ +AE L+ GK+GSFLVR S++ Y L V R V ++ ++ +
Sbjct: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
Query: 450 NKYDV 464
+K+ V
Sbjct: 61 DKFTV 65
>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to SH2 domain containing 4B - Canis
familiaris
Length = 488
Score = 43.2 bits (97), Expect = 0.007
Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 461
WFHG++S ++AE L +E G+FLVR S+ G Y LS R++ H L+ + Y
Sbjct: 382 WFHGIISREDAEDL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLVDASGDFYSF 439
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTR 581
+G + L LI+ F +I SG LLQ G R
Sbjct: 440 LGVDPNRHATLTDLID-FHKEEIITVSGG--ELLQEPCGQR 477
>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
Danio rerio
Length = 250
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/94 (27%), Positives = 48/94 (51%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
+ WF S AE +M + + G+FL+R SQ+ PG++ +SVR V H + + +
Sbjct: 55 IPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSG 113
Query: 456 YDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRL 557
+ E+F L L++ +++ + + LRL
Sbjct: 114 HYYLWTEKFTSLNKLVDFYKTTSISKQKEIFLRL 147
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 43.2 bits (97), Expect = 0.007
Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 10/106 (9%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ----HN 452
W+HG + + AE+L+ ++G FL+R+S + PG YVL+ + + H I ++ +
Sbjct: 46 WYHGAIPRQVAENLVQ---RDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRVVAMNE 102
Query: 453 KYD----VGSGEQFDDLVGLIEHF--RSYPMIETSGDVLRLLQPVS 572
Y + E FD + L+ ++ P+ E G + + QP++
Sbjct: 103 AYSRVQYLFEKEGFDSIPALVRYYVGNREPVSEVIGAI--IFQPIN 146
>UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;
n=2; Euteleostomi|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 519
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Frame = +3
Query: 222 AAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLS 401
++G +V T L E K + W+ G ++ EAE ++ +GSFLVR+S LS
Sbjct: 347 SSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEEKLVNL-PDGSFLVRDSSDDRYLLSLS 405
Query: 402 VRVRGRVSHVLIRRQHNK---YDVGSGEQFDDLVGLIEH 509
R +G+ H I + + Y+ E +V LIEH
Sbjct: 406 FRSQGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEH 444
>UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14770, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 789
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQHNKYD 461
W+H ++ +AE L+ + ++GSFL+R+S++ G Y L V + V ++ ++ +H K
Sbjct: 1 WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYALCVLYQKCVYTYRILPSEHMKLS 60
Query: 462 VGSGE 476
V + E
Sbjct: 61 VQASE 65
>UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 123
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR-VRGRVSHVLIRRQHNKY 458
+W+HG +S EAE L+ K S+LVR SQ + EY LS+R +G + L + + KY
Sbjct: 51 RWYHGSLSRSEAECLLT-LCKECSYLVRTSQTNHSEYSLSLRSCQGFMHMKLTQCKDGKY 109
Query: 459 DVGSGEQFDDLV 494
+G D +
Sbjct: 110 VLGQNSPLFDTI 121
>UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 253
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/100 (23%), Positives = 53/100 (53%), Gaps = 5/100 (5%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG +S ++AE+ + ++ + SFLVR+S++ +Y ++++ H+++ + +
Sbjct: 154 WYHGSVSRQQAEAQL-QRCREASFLVRDSESGTSKYSIALKTSQSCVHIIVAQTKGVKGL 212
Query: 465 G-----SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
G S F + L+ H+ ++ + T + + L PV
Sbjct: 213 GFTLDQSSCVFPSIPELVHHYCTHRLPFTGAEHMTLQHPV 252
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 43.2 bits (97), Expect = 0.007
Identities = 29/116 (25%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Frame = +3
Query: 228 GAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVR 407
G + + L +++ + W+HG ++ EAE+ + + GSFLVR ++ +Y LS++
Sbjct: 1297 GYVTAVDLIDVTIPLERQGWYHGAITRIEAETTLRPLSE-GSFLVRNCESTKQDYSLSLK 1355
Query: 408 VRGRVSHVLIRR-QHNKYDVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
H+ I+R + +Y +G F+ + +I HF + + + L++PV
Sbjct: 1356 GAKGFMHMRIQRNETGQYILGQFSRPFETVPEMIRHFCLNRLPVRGAEHMCLIEPV 1411
>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
Euteleostomi|Rep: Novel SH2 domain-containing protein -
Homo sapiens (Human)
Length = 431
Score = 43.2 bits (97), Expect = 0.007
Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD- 461
WFHG++S ++AE+L +E G+FLVR S+ G Y LS R++ H L+ + Y
Sbjct: 325 WFHGIISREDAEAL-LENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKHFLVDASGDFYSF 382
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTR 581
+G + L L++ F +I SG LLQ G R
Sbjct: 383 LGVDPNRHATLTDLVD-FHKEEIITVSGG--ELLQEPCGQR 420
>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
SRC-like-adapter - Homo sapiens (Human)
Length = 276
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/75 (34%), Positives = 37/75 (49%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 467
F G+ K E L + K GSF++RES+ G Y LSVR R + + R +N Y +
Sbjct: 86 FEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYIS 145
Query: 468 SGEQFDDLVGLIEHF 512
F L L+ H+
Sbjct: 146 PRLTFQCLEDLVNHY 160
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 43.2 bits (97), Expect = 0.007
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNKY 458
WF G +S EA + +G G+FL+R S+ +YVLSVR V H I RR +
Sbjct: 78 WFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRL 137
Query: 459 DVGSGEQFDDLVGLIEHFRS 518
+ F L L+ + R+
Sbjct: 138 HLNEAVSFLSLPELVNYHRA 157
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 43.2 bits (97), Expect = 0.007
Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 6/85 (7%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAE-SLIMEKGKNGSFLVRESQAHPGEYVLSVR---VRGR-VSHVLIR 440
+++WF KEAE L+ K GSFL+RES+ + G + LSV+ +G + H IR
Sbjct: 121 MERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIR 180
Query: 441 -RQHNKYDVGSGEQFDDLVGLIEHF 512
Y + F L L++H+
Sbjct: 181 CLDEGGYYISPRITFPSLQALVQHY 205
>UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol
polyphosphate 5- phosphatase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to inositol
polyphosphate 5- phosphatase - Ornithorhynchus anatinus
Length = 1019
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Frame = +3
Query: 273 MLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV-SHVLIRRQH 449
M+ W HG ++ +AE L+ + GK+GSFLVR S++ Y L V V ++ ++
Sbjct: 1 MVHCWNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCVLYHNCVYTYRILPNDD 60
Query: 450 NKYDVGSGEQ-----FDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
K+ V + E F L LI+ ++ E G V L PV
Sbjct: 61 EKFTVQASEGVPMRFFTSLEQLIDFYKK----ENMGLVTHLQYPV 101
>UniRef50_UPI0000F1FADE Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 324
Score = 42.7 bits (96), Expect = 0.009
Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
Frame = +3
Query: 237 VSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRV 410
V+ ++++ M +W+ G +S EAE + + K+G+FLVR+S E Y L V
Sbjct: 196 VNEKMEQICSQDMDPQWYVGQISRGEAEVSLRKVKKDGTFLVRDSSKGCEEQPYTLMVLH 255
Query: 411 RGRVSHVLIRRQHNK--YDVGSG----EQFDDLVGLIEHFRSYPMIETSG 542
+ +V ++ IR NK Y +G+G E + + +I H P+ G
Sbjct: 256 QQKVYNIQIRFLGNKDGYSLGTGLNGIENYSSVAEMIMHHMKNPLFLIDG 305
>UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep:
MGC68984 protein - Xenopus laevis (African clawed frog)
Length = 266
Score = 42.7 bits (96), Expect = 0.009
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Frame = +3
Query: 198 DASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIM-EKGKNGSFLVRESQ 374
D L V +A L A + +W + ++ ++AE L+M ++GSFL+RES+
Sbjct: 60 DGDWLKVSSASTGQECYLPTNYVAKVCNRWLYKGINREKAEELLMVNSNRSGSFLIRESE 119
Query: 375 AHPGEYVLSVRVRGRVSHVLIR 440
G Y LS+R S I+
Sbjct: 120 TRSGSYTLSIRKTNHTSRDSIK 141
>UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 666
Score = 42.7 bits (96), Expect = 0.009
Identities = 21/51 (41%), Positives = 33/51 (64%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI 437
W+H MS ++AE L++ ++G FLVRES + G+YVL+ G H+L+
Sbjct: 571 WYHSRMSRRDAERLLI---RDGDFLVRESTTNLGQYVLTGMHCGLPKHLLL 618
>UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:
CG3208-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 494
Score = 42.7 bits (96), Expect = 0.009
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
Frame = +3
Query: 144 PRLSRLGVLAPAALSACMDASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAES 323
P L +L + APA + L +P A + V + +HG+M EAE
Sbjct: 36 PELYKLQLEAPAPCPLRCQRT-LPLPPAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQ 94
Query: 324 LIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH--VLIRRQHNKYDVGSGEQFDDLVG 497
L + ++GS+ VR S G Y LS+R R H +L + Y G ++FD +
Sbjct: 95 L-LANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKRFDTVHD 153
Query: 498 LI 503
++
Sbjct: 154 MV 155
>UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF15007, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 868
Score = 42.3 bits (95), Expect = 0.012
Identities = 19/53 (35%), Positives = 35/53 (66%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + + +ESL++ +G FL+R+SQ++ G +VL+ + + H LIR+
Sbjct: 280 WYHGPIPWEVSESLVVN---HGDFLIRDSQSNRGNFVLTSNWQQKTLHFLIRK 329
>UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF15108, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 877
Score = 42.3 bits (95), Expect = 0.012
Identities = 22/88 (25%), Positives = 45/88 (51%)
Frame = +3
Query: 270 FMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQH 449
F L + F G M +AE+ ++ + N ++LVR EY +S++ V H+ I +
Sbjct: 680 FPLLRRFAGPMERLQAEAELINR-VNSTYLVRHRSREYTEYAISIKYNNDVKHIKILTKE 738
Query: 450 NKYDVGSGEQFDDLVGLIEHFRSYPMIE 533
+ + ++F + LIE+++ + + E
Sbjct: 739 GCFYIAENKKFRSISELIEYYKHHSLRE 766
>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 271
Score = 42.3 bits (95), Expect = 0.012
Identities = 25/75 (33%), Positives = 35/75 (46%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVG 467
F GV K E L + GSFL+RES G Y LSVR R + + R ++ Y +
Sbjct: 86 FEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVRHRSVKHYKIFRLTNSWYYIS 145
Query: 468 SGEQFDDLVGLIEHF 512
F L ++ H+
Sbjct: 146 PRLTFQCLEDMVNHY 160
>UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep:
Zgc:158798 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 391
Score = 42.3 bits (95), Expect = 0.012
Identities = 29/97 (29%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-QHNKYD 461
W+HG +S EAESL + K S+LVR S+ +Y LS+R H+ + + +Y
Sbjct: 291 WYHGSLSRSEAESL-LTLCKECSYLVRNSETSRLDYSLSLRSCQGFMHMKFSQCKDGRYI 349
Query: 462 VG-SGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G + F+ + +I ++ ++ + + L LL PV
Sbjct: 350 LGQNSPPFETIPEVIHYYTTHKLPIKGAEHLSLLFPV 386
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Frame = +3
Query: 219 PAAGAI-VSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEK-GKNGSFLVRESQAHPGEY 392
P+AG + ++ V K + + W+ +S +A+ L++ + G+FL+R S++ G Y
Sbjct: 97 PSAGLVPITHVAKASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGY 156
Query: 393 VLSVRVRGRVSHVLI-RRQHNKYDVGSGEQFDDLVGLIEHFRS 518
LSVR + +V H + + G F L L+ ++++
Sbjct: 157 SLSVRAQAKVCHYRVSMAADGSLYLQKGRLFPGLEELLTYYKA 199
>UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance
protein 3; n=34; Euteleostomi|Rep: Breast cancer
anti-estrogen resistance protein 3 - Homo sapiens
(Human)
Length = 825
Score = 42.3 bits (95), Expect = 0.012
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 10/108 (9%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W+HG + + +E+L+ ++G FLVR+S + PG +VL+ + + H I R +
Sbjct: 154 WYHGRIPRQVSENLVQ---RDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSE 210
Query: 465 GSG--------EQFDDLVGLIEHF--RSYPMIETSGDVLRLLQPVSGT 578
E FD + GL+ + P+ + SG + + QP++ T
Sbjct: 211 AYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAI--IFQPINRT 256
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 41.9 bits (94), Expect = 0.016
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Frame = +3
Query: 249 LKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSH 428
LK ++ + W+HG + + E L+ G++G FLVR+S G+YVL+ + + H
Sbjct: 15 LKLSTEDLRSQAWYHGQLQREATEQLL---GRDGEFLVRDSSTSAGDYVLTCMWKNQPMH 71
Query: 429 VLIRRQHNKYDVG--------SGEQFDDLVGLIE-HFRS-YPMIETSGDVLRLLQPVSGT 578
I R + G +QFD++ LI H P+ ++G V + QP++ T
Sbjct: 72 FKIIRITLRPKQGYTRELFQFENDQFDNIPALIRFHVGGRRPISHSTGAV--IFQPITRT 129
>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 284
Score = 41.9 bits (94), Expect = 0.016
Identities = 23/81 (28%), Positives = 43/81 (53%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNK 455
+ WF S AE +M + + G+FL+R SQ+ PG++ +SVR V H + + +
Sbjct: 55 IPSWFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSG 113
Query: 456 YDVGSGEQFDDLVGLIEHFRS 518
+ E+F L L++ +++
Sbjct: 114 HYYLWTEKFTSLNKLVDFYKT 134
>UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF12132, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 422
Score = 41.9 bits (94), Expect = 0.016
Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGS--FLVRESQAHPGEYVLSVRVRGR 419
WFHG +S +A L+ G G FLVR+S+ G+YVL+ +G+
Sbjct: 135 WFHGPISRVKAAHLVQSSGPEGHGVFLVRQSETRRGDYVLTFNYQGK 181
>UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 948
Score = 41.9 bits (94), Expect = 0.016
Identities = 36/96 (37%), Positives = 54/96 (56%), Gaps = 10/96 (10%)
Frame = +3
Query: 261 SKAFMLKK--WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVS-HV 431
S A L+K WFHG ++A+ AE L+ +G G FLVRE A PG Y ++VR + + + H+
Sbjct: 48 SAARQLEKSPWFHGKITAEYAEMLM--RGA-GEFLVREDPAMPGMYFIAVRNKEQETLHL 104
Query: 432 LIRRQHN------KYDV-GSGEQFDDLVGLIEHFRS 518
I + ++ KY V S FD + LI+ + S
Sbjct: 105 AITKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYIS 140
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 41.9 bits (94), Expect = 0.016
Identities = 30/86 (34%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVR----VRGR-VSHVLIRRQ 446
WF +S K+AE ++ G +GSFL+RES++ G + LSVR +G V H IR
Sbjct: 185 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNL 244
Query: 447 HN-KYDVGSGEQFDDLVGLIEHFRSY 521
N + + F L L+ H+ Y
Sbjct: 245 DNGGFYISPRITFPGLHELVRHYTRY 270
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 41.9 bits (94), Expect = 0.016
Identities = 18/38 (47%), Positives = 25/38 (65%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVL 398
W+H +S AE L+ G +GSFLVR+S++ PG Y L
Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYAL 43
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 41.9 bits (94), Expect = 0.016
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 7/112 (6%)
Frame = +3
Query: 201 ASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKN-GSFLVRESQA 377
A LA G I S + + + ++WF +S K+AE ++ G GSF++R+S+
Sbjct: 117 ARSLATRKEGYIPSNYVARVD-SLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSET 175
Query: 378 HPGEYVLSV-----RVRGRVSHVLIRRQHN-KYDVGSGEQFDDLVGLIEHFR 515
G Y LSV R V H IR N + + F L L++H++
Sbjct: 176 TKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYK 227
>UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 457
Score = 41.5 bits (93), Expect = 0.021
Identities = 24/102 (23%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLI-RRQHNK 455
+ W+HG +S +EAE+ + ++ + SFLVR+S++ +Y ++++ H+++ + +
Sbjct: 356 QSWYHGSVSRQEAEAQL-QQCREASFLVRDSESATSKYSIALKTSQGCVHIIVAQTKECG 414
Query: 456 YDV-GSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGT 578
Y + S F + ++ H+ + + T + + L PV T
Sbjct: 415 YTLEKSSCVFPSIPEVVHHYCTQRLPFTGAEHMTLQHPVPRT 456
>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
SH2D3C protein - Gallus gallus
Length = 603
Score = 41.5 bits (93), Expect = 0.021
Identities = 19/53 (35%), Positives = 31/53 (58%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR 443
W+HG + + +ESL+ +NG F++R+S G+YVL+ R R H I +
Sbjct: 63 WYHGRIPREVSESLVQ---RNGDFIIRDSLTSVGDYVLTCRWRNEPLHFKINK 112
>UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14981, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 912
Score = 41.5 bits (93), Expect = 0.021
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WF G M +AE ++E+ N ++LVR EY LS++ +V H+ I + + +
Sbjct: 720 WFAGPMERSQAELELLERN-NSTYLVRHRTRECTEYALSIKFNDKVKHIKILTKDGCFYI 778
Query: 465 GSGEQFDDLVGLIEHFR 515
F ++ H R
Sbjct: 779 AESRLFKTVLPTGSHIR 795
>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
3-kinase regulatory subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 568
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/98 (25%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYD 461
+W+ G ++ E + + + +GSFLVR++ + GEY L+++ G + I +KY
Sbjct: 185 EWYWGNINRDEVKEKMTDV-PDGSFLVRDASSGNGEYTLTLKKDGADRVIKIFHTQDKYG 243
Query: 462 VGSGEQFDDLVGLIEHFRSYPMIETSGDV-LRLLQPVS 572
+ +V LI +R+ + E + + ++L+ P+S
Sbjct: 244 FTRDGSHNSVVDLINFYRNVSLKEYNTILDIKLMYPIS 281
Score = 35.1 bits (77), Expect = 1.8
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
W + +AE + K NG+F++R P Y LS++ V+H +I++ Y
Sbjct: 466 WLVPTFNRTDAEKELASK-PNGTFVIRPGSGGP--YALSIKCNDTVNHCIIQQTDRGYGF 522
Query: 465 GSGEQ-FDDLVGLIEHFRSYPMIETSGDVLR 554
+D L L+ H+ + +E D L+
Sbjct: 523 AEPYNIYDSLKSLVLHYAT-NSLEEHNDTLQ 552
>UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia
roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea
squirt)
Length = 867
Score = 41.5 bits (93), Expect = 0.021
Identities = 21/54 (38%), Positives = 30/54 (55%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQ 446
WFHG M AE LI + G FL+RES + GE+VL+ + + H I ++
Sbjct: 51 WFHGRMPRDIAEDLIR---REGDFLIRESVNNAGEFVLTCKYKSATYHFKINKK 101
>UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21;
Euteleostomi|Rep: Src-like-adapter 2 - Homo sapiens
(Human)
Length = 261
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVR-----GRVSHVLIRRQ 446
W + +S ++AE L++ G G+FL+RESQ G Y LSVR+ R+ H I
Sbjct: 94 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCL 153
Query: 447 HNKY-DVGSGEQFDDLVGLIEHF 512
N + + F L L++H+
Sbjct: 154 DNGWLYISPRLTFPSLQALVDHY 176
>UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8;
Eutheria|Rep: SH2 domain-containing protein 1A - Mus
musculus (Mouse)
Length = 126
Score = 41.5 bits (93), Expect = 0.021
Identities = 17/45 (37%), Positives = 30/45 (66%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 422
+HG +S + E L++ G +GS+L+R+S++ PG Y L V +G +
Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYI 51
>UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 197
Score = 41.1 bits (92), Expect = 0.027
Identities = 17/45 (37%), Positives = 30/45 (66%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 422
+HG +S + E L++ G +GS+L+R+S++ PG Y L V +G +
Sbjct: 7 YHGNISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYI 51
>UniRef50_UPI0000567EFA Cluster: UPI0000567EFA related cluster; n=2;
Danio rerio|Rep: UPI0000567EFA UniRef100 entry - Danio
rerio
Length = 486
Score = 41.1 bits (92), Expect = 0.027
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 8/95 (8%)
Frame = +3
Query: 282 KWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE--YVLSVRVRGRVSHVLIRRQHNK 455
+W+ G +S EAE + + K+G+FLVR+S E Y L V + +V ++ IR NK
Sbjct: 373 QWYVGQISRGEAEVSLRKVKKDGTFLVRDSSKGCEEQPYTLMVLHQQKVYNIQIRFLGNK 432
Query: 456 --YDVGSG----EQFDDLVGLIEHFRSYPMIETSG 542
Y +G+G E + + +I H P+ G
Sbjct: 433 DGYSLGTGLNGIENYSSVAEMIMHHMKNPLFLIDG 467
>UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound
protein 14 (GRB14 adapter protein).; n=5; Tetrapoda|Rep:
Growth factor receptor-bound protein 14 (GRB14 adapter
protein). - Xenopus tropicalis
Length = 428
Score = 41.1 bits (92), Expect = 0.027
Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 6/83 (7%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSH---VLIRRQHN 452
WFH +S EA+ LI+++G +G F++R+SQ+ +VLS+ +V H V + +
Sbjct: 327 WFHHQLSRDEAQKLILQQGLVDGVFILRDSQSTHKAFVLSMCHGQKVKHFQIVPVEEDGD 386
Query: 453 KYDVGSGEQ--FDDLVGLIEHFR 515
+ Q F DL+ L+E ++
Sbjct: 387 HFFTLDNAQTKFTDLIQLVEFYK 409
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 41.1 bits (92), Expect = 0.027
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR--QHNKY 458
W+HG +S +AE ++ + GSFLVR S++ +Y L+++ H+ I+R ++
Sbjct: 609 WYHGSISRIDAEKILRPLSE-GSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDADSGQF 667
Query: 459 DVGS-GEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPV 569
+G F + +I HF + + + LL+PV
Sbjct: 668 ILGQFSRPFPTIPDMIRHFCLNRLPVRGAEHMCLLEPV 705
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 41.1 bits (92), Expect = 0.027
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDV 464
WFH ++ EAE LI + + GSFLVR S+ P ++ L+++ + + + R ++ +
Sbjct: 55 WFHPSLTRSEAEELIRNEPE-GSFLVRPSETCPNDFSLTIKHKTFLHMKITRNNAGQFIL 113
Query: 465 GSGEQ-FDDLVGLIEHF 512
G Q + + +I H+
Sbjct: 114 GEYSQPYSSVSQMIYHY 130
>UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55;
Euteleostomi|Rep: Tyrosine-protein kinase ZAP-70 - Homo
sapiens (Human)
Length = 619
Score = 41.1 bits (92), Expect = 0.027
Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGK-NGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRR-QHNKY 458
W+H ++ +EAE + + +G FL+R + G Y LS+ V H LI + + KY
Sbjct: 163 WYHSSLTREEAERKLYSGAQTDGKFLLR-PRKEQGTYALSLIYGKTVYHYLISQDKAGKY 221
Query: 459 DVGSGEQFDDLVGLIEHFR 515
+ G +FD L L+E+ +
Sbjct: 222 CIPEGTKFDTLWQLVEYLK 240
>UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;
Euteleostomi|Rep: SH2 domain-containing protein 1A -
Homo sapiens (Human)
Length = 128
Score = 41.1 bits (92), Expect = 0.027
Identities = 17/45 (37%), Positives = 29/45 (64%)
Frame = +3
Query: 288 FHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRV 422
+HG +S + E L++ G +GS+L+R+S++ PG Y L V G +
Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYI 51
>UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31;
n=4; Caenorhabditis|Rep: Probable tyrosine-protein
kinase kin-31 - Caenorhabditis elegans
Length = 437
Score = 41.1 bits (92), Expect = 0.027
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Frame = +3
Query: 285 WFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE---YVLSVRVRGR------VSHVLI 437
+FHG++ ++ L+ NG ++VR S PGE Y+LSV + V H +I
Sbjct: 20 YFHGLIQREDVFQLL---DNNGDYVVRLSDPKPGEPRSYILSVMFNNKLDENSSVKHFVI 76
Query: 438 RRQHNKYDVGSGEQFDDLVGLIEHFR 515
NKY V + F+ + ++ H++
Sbjct: 77 NSVENKYFVNNNMSFNTIQQMLSHYQ 102
>UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing
protein; n=2; Murinae|Rep: Hematopoietic SH2
domain-containing protein - Mus musculus (Mouse)
Length = 334
Score = 41.1 bits (92), Expect = 0.027
Identities = 19/55 (34%), Positives = 34/55 (61%)
Frame = +3
Query: 276 LKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIR 440
+ +WFHG +S + AE++ +E G+FL+R S +H G Y LS + + H +++
Sbjct: 31 IPEWFHGTISREAAENM-LESQPLGTFLIRVSHSHVG-YTLSYKAQTCCRHFMVK 83
>UniRef50_UPI0000F1E8DC Cluster: PREDICTED: similar to B-cell
linker; n=1; Danio rerio|Rep: PREDICTED: similar to
B-cell linker - Danio rerio
Length = 390
Score = 40.7 bits (91), Expect = 0.036
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Frame = +3
Query: 279 KKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGE-YVLSVRVRGRVSHVLIR--RQH 449
K WF G K AE ++ K+G+FLVR S + + Y L V V ++ +R
Sbjct: 279 KDWFAGDCDRKTAEETVLRMNKDGTFLVRFSNSQNSQPYTLVVLYHQNVYNIPVRFLEDS 338
Query: 450 NKYDVGSG-----EQFDDLVGLIEHFRSYPMI 530
+Y +G G E F L +I H P++
Sbjct: 339 QQYVLGKGGKKSEELFSSLQEMISHHMMNPIL 370
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 734,265,494
Number of Sequences: 1657284
Number of extensions: 15311647
Number of successful extensions: 51641
Number of sequences better than 10.0: 351
Number of HSP's better than 10.0 without gapping: 49026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51499
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59265488880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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