Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_E05
(894 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 288 1e-76
UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|R... 246 6e-64
UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium t... 237 2e-61
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 231 2e-59
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 229 7e-59
UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Re... 227 3e-58
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 221 2e-56
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ... 220 3e-56
UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=... 208 1e-52
UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium t... 207 3e-52
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 207 3e-52
UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Re... 201 2e-50
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 198 1e-49
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 196 5e-49
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 195 1e-48
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas... 195 1e-48
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 194 2e-48
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad... 194 3e-48
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 185 1e-45
UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Re... 176 5e-43
UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmi... 175 9e-43
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 173 4e-42
UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella ve... 166 8e-40
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo... 148 2e-34
UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;... 115 1e-24
UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella chej... 107 5e-22
UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate deh... 99 1e-19
UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;... 93 7e-18
UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21; Amniota|... 87 8e-16
UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep: Zgc:1... 79 1e-13
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 72 2e-11
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 65 2e-09
UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD (so... 65 3e-09
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 59 1e-07
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 59 1e-07
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 58 3e-07
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 58 3e-07
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 56 9e-07
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 56 1e-06
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 55 2e-06
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 53 1e-05
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 52 2e-05
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 52 3e-05
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 52 3e-05
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 50 6e-05
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 49 2e-04
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 48 4e-04
UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to tetratrico... 47 6e-04
UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 46 0.002
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 45 0.003
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 44 0.007
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 44 0.007
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 43 0.009
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 43 0.009
UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein NCU048... 43 0.012
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 43 0.012
UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 42 0.028
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 42 0.028
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 40 0.065
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 40 0.065
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 39 0.15
UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4; Euteleost... 39 0.20
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 38 0.35
UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium salinarum|... 38 0.46
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 38 0.46
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 37 0.60
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 37 0.80
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 36 1.1
UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep... 36 1.4
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 36 1.4
UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep... 36 1.4
UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genom... 36 1.8
UniRef50_O97299 Cluster: Putative uncharacterized protein MAL3P7... 36 1.8
UniRef50_Q9BYR4 Cluster: Keratin-associated protein 4-3; n=53; M... 36 1.8
UniRef50_Q827S2 Cluster: Putative aminodeoxychorismate lyase; n=... 35 2.4
UniRef50_Q2RQ78 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7; ... 35 2.4
UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P... 35 2.4
UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidas... 35 2.4
UniRef50_Q8YTB2 Cluster: Valine-pyruvate aminotransferase; n=9; ... 35 3.2
UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein fa... 35 3.2
UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococ... 34 4.3
UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Ce... 34 4.3
UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin as... 34 5.6
UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep... 34 5.6
UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6
UniRef50_Q1JTH9 Cluster: Hyothetical protein; n=4; root|Rep: Hyo... 34 5.6
UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34; Prote... 34 5.6
UniRef50_UPI00006CFE65 Cluster: hypothetical protein TTHERM_0069... 33 7.4
UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep: ... 33 7.4
UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3; Sordariom... 33 7.4
UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila mela... 33 7.4
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 33 7.4
UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47; Craniat... 33 7.4
UniRef50_UPI0000F21642 Cluster: PREDICTED: hypothetical protein;... 33 9.8
UniRef50_Q88SJ4 Cluster: Extracellular protein, gamma-D-glutamat... 33 9.8
UniRef50_A6W575 Cluster: Putative uncharacterized protein; n=1; ... 33 9.8
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase,
cytoplasmic - Homo sapiens (Human)
Length = 334
Score = 288 bits (707), Expect = 1e-76
Identities = 137/194 (70%), Positives = 160/194 (82%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 325
M+EPIRV+VTGAAGQIAYSLLY I +G+VFG QP+ L LLDI PMMGVL+GV+MEL DC
Sbjct: 1 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC 60
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
ALPLL V+ T + AFKD+ A LVG+MPR+EGMERKDLL ANV+IFK QG ALDK A
Sbjct: 61 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA 120
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
+K VKV+VVGNPANTN L SK APSIPKENF+ +TRLD NRA++Q+A K+GV DVK
Sbjct: 121 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN 180
Query: 686 VIIWGNHSSTQFPE 727
VIIWGNHSSTQ+P+
Sbjct: 181 VIIWGNHSSTQYPD 194
Score = 44.0 bits (99), Expect = 0.005
Identities = 20/32 (62%), Positives = 25/32 (78%)
Frame = +3
Query: 756 GAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
G + V E + DD++LKG FVTTVQ+RGAAVI
Sbjct: 204 GKEVGVYEALKDDSWLKGEFVTTVQQRGAAVI 235
>UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|Rep:
Malate dehydrogenase - Caenorhabditis elegans
Length = 336
Score = 246 bits (602), Expect = 6e-64
Identities = 121/195 (62%), Positives = 147/195 (75%), Gaps = 1/195 (0%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 325
M+ P+RV+VTGAAGQI YS++ +IA G VFG +QPV L LLD+ +LEGVV EL DC
Sbjct: 1 MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDC 60
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
ALP L V+ + + AF + AFLVGAMPR+EGMERKDLLAANV+IFK QG+AL + A
Sbjct: 61 ALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKDLLAANVKIFKSQGKALAEYA 120
Query: 506 RKDVKVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 682
+ KV+VVGNPANTNA I +KYA IP +NF+AMTRLD NRA +QLA K G + +VK
Sbjct: 121 KPTTKVIVVGNPANTNAFIAAKYAAGKIPAKNFSAMTRLDHNRALAQLALKTGTTIGNVK 180
Query: 683 RVIIWGNHSSTQFPE 727
VIIWGNHS TQFP+
Sbjct: 181 NVIIWGNHSGTQFPD 195
Score = 35.1 bits (77), Expect = 2.4
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = +3
Query: 726 NASNAVXIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
+ ++A G + + D+A+L+G F+ TVQKRG +I
Sbjct: 195 DVTHATVNKNGTETDAYAAVGDNAFLQGPFIATVQKRGGVII 236
>UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 356
Score = 237 bits (581), Expect = 2e-61
Identities = 113/191 (59%), Positives = 141/191 (73%)
Frame = +2
Query: 155 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 334
P+RV VTGAAG I Y+L++ I G + GP Q + L LL++ LEG +MEL DCA P
Sbjct: 26 PVRVTVTGAAGNIGYALVHMIGQGRLLGPNQQIILTLLELPMAKDQLEGTMMELRDCAFP 85
Query: 335 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 514
+L + T ++ F A LVGA PR GMERKDLLAAN RIFKEQG+AL+K A K+
Sbjct: 86 ILKEIRGTTQYDQGFMGCEIAILVGAKPRGPGMERKDLLAANARIFKEQGEALEKYASKN 145
Query: 515 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 694
VKVLVVGNPANTNALI +++APSIPK NFTA+TRLDQNRAQS +A ++ V+DV+ +II
Sbjct: 146 VKVLVVGNPANTNALITAQFAPSIPKSNFTALTRLDQNRAQSIIAQRVSANVEDVRNIII 205
Query: 695 WGNHSSTQFPE 727
WGNHS+TQF +
Sbjct: 206 WGNHSTTQFAD 216
Score = 35.1 bits (77), Expect = 2.4
Identities = 17/42 (40%), Positives = 25/42 (59%)
Frame = +3
Query: 726 NASNAVXIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
+ S A G ++V ++ DDA+L+ AFV V KRG A+I
Sbjct: 216 DVSQATVQQNGISQTVRGLVADDAWLQKAFVEQVAKRGGAII 257
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 231 bits (565), Expect = 2e-59
Identities = 115/194 (59%), Positives = 140/194 (72%), Gaps = 2/194 (1%)
Frame = +2
Query: 152 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAP--MMGVLEGVVMELADC 325
+P+RV VTGAAGQI Y+LL++IASG + G QPV L LL+I L+GV+MEL DC
Sbjct: 4 KPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDC 63
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
A PLLAG+ ++P AFKD A LVGA PR GMER DLLAAN +IF QG+AL+ A
Sbjct: 64 AFPLLAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVA 123
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
++VKVLVVGNPANTNA I K AP +P +NFTAM RLD NRA SQLAAK G V D+K+
Sbjct: 124 SRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQLAAKGGFKVGDIKK 183
Query: 686 VIIWGNHSSTQFPE 727
+ +WGNHS T + +
Sbjct: 184 LTVWGNHSPTMYAD 197
Score = 37.1 bits (82), Expect = 0.60
Identities = 17/29 (58%), Positives = 21/29 (72%)
Frame = +3
Query: 765 KSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
KSV + IND A+ K F+ TV KRGAA+I
Sbjct: 206 KSVKDAINDPAWYKDVFLPTVGKRGAAII 234
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 229 bits (560), Expect = 7e-59
Identities = 109/192 (56%), Positives = 138/192 (71%)
Frame = +2
Query: 152 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 331
+P++V+VTGAAGQI Y+++ IA G + G QPV LHLLD+ L GV MEL D AL
Sbjct: 25 KPVKVLVTGAAGQIGYAIVAMIAKGLMLGADQPVVLHLLDLPVAANALNGVRMELIDAAL 84
Query: 332 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
PLL GV+ T++ EAFK V A L+G PR++GMERKDL++ NV I+K Q AL + A
Sbjct: 85 PLLRGVVATSDEAEAFKGVNVAILIGGWPRRDGMERKDLISKNVTIYKSQASALQQHAAP 144
Query: 512 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
+ KVLVV NPANTNAL+ ++AP+IP +N T +TRLD NRA Q+A K+ V V DVK I
Sbjct: 145 NCKVLVVANPANTNALVLKEFAPAIPAKNITCLTRLDHNRALGQVAEKLNVHVGDVKNAI 204
Query: 692 IWGNHSSTQFPE 727
IWGNHSSTQFP+
Sbjct: 205 IWGNHSSTQFPD 216
Score = 38.7 bits (86), Expect = 0.20
Identities = 19/42 (45%), Positives = 28/42 (66%)
Frame = +3
Query: 726 NASNAVXIVGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
+AS+A ++ V E+I D+ +L+ FVT VQ+RGAAVI
Sbjct: 216 DASHATVSTDRGERPVRELIADEIWLREEFVTDVQQRGAAVI 257
>UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Rep:
Malate dehydrogenase - Frankia sp. (strain CcI3)
Length = 329
Score = 227 bits (555), Expect = 3e-58
Identities = 109/193 (56%), Positives = 139/193 (72%)
Frame = +2
Query: 155 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 334
P+ V VTGAAGQI Y+LL++IASG + G PV L LL+I + EG +EL D A P
Sbjct: 5 PVNVTVTGAAGQIGYALLFRIASGQLLGADTPVKLRLLEIPQAVRAAEGTALELEDSAFP 64
Query: 335 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 514
LLAGV + + AF+ A LVGA PR +GMER DLL+AN IFK QG+A++ A +D
Sbjct: 65 LLAGVDVFDDAKRAFEGTNVALLVGARPRTKGMERGDLLSANGGIFKPQGEAINSGAAED 124
Query: 515 VKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 694
++VLVVGNPANTNALI +AP +P E FTAMTRLD NRA +QLA K+GVP ++K++ I
Sbjct: 125 IRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLDHNRAIAQLAKKLGVPSAEIKKITI 184
Query: 695 WGNHSSTQFPECF 733
WGNHS+TQ+P+ F
Sbjct: 185 WGNHSATQYPDIF 197
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 221 bits (540), Expect = 2e-56
Identities = 115/199 (57%), Positives = 136/199 (68%), Gaps = 5/199 (2%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMG--VLEGVVMELA 319
M P+RV VTGAAGQI Y+LL++IASGA+ G QPV L LL+I L+GV+MEL
Sbjct: 1 MKAPVRVAVTGAAGQIGYALLFRIASGAMLGADQPVILQLLEIPDEKAQKALKGVMMELE 60
Query: 320 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 499
DCA PLL ++ T +P AFKD A LVGA PR GMERKDLL AN +IF QG+A+ K
Sbjct: 61 DCAFPLLHSMIATGDPAVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGK 120
Query: 500 AARKDVKVLVVGNPANTNALICSKYAPS---IPKENFTAMTRLDQNRAQSQLAAKIGVPV 670
A +VKVLVVGNPANTNA I K A + +NFTAM RLD NRA SQLA K G PV
Sbjct: 121 YANPNVKVLVVGNPANTNAYIAMKSAMKHGRVKAKNFTAMLRLDHNRALSQLATKTGKPV 180
Query: 671 KDVKRVIIWGNHSSTQFPE 727
K+V +WGNHS T +P+
Sbjct: 181 ASFKKVAVWGNHSPTMYPD 199
>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
putative - Leishmania major
Length = 324
Score = 220 bits (538), Expect = 3e-56
Identities = 115/191 (60%), Positives = 132/191 (69%), Gaps = 1/191 (0%)
Frame = +2
Query: 158 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 337
++V VTGAAGQI Y+L+ IA GA+ GP PV L LLDI P + L GV EL DCA PL
Sbjct: 4 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 63
Query: 338 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDV 517
L V+ TA+P AF VA A + GA PRK GMERKDLL N RIFKEQG+A+ A D
Sbjct: 64 LDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASDC 123
Query: 518 KVLVVGNPANTNALICSKYAP-SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVII 694
+V+VVGNPANTNALI K A + + TAMTRLD NRA S LA K GVPV V+ VII
Sbjct: 124 RVVVVGNPANTNALILLKSAQGKLNPRHVTAMTRLDHNRALSLLARKAGVPVSQVRNVII 183
Query: 695 WGNHSSTQFPE 727
WGNHSSTQ P+
Sbjct: 184 WGNHSSTQVPD 194
>UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=2;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 1 - Entamoeba histolytica
Length = 355
Score = 208 bits (508), Expect = 1e-52
Identities = 105/193 (54%), Positives = 132/193 (68%)
Frame = +2
Query: 149 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCA 328
++P+ V+VTGAAGQI Y+LL+ IA G +FGP Q V+LHL DI M+ +EGV MELADC
Sbjct: 22 SKPLHVLVTGAAGQIGYNLLFLIAHGLMFGPNQTVYLHLYDI--MVEAMEGVKMELADCC 79
Query: 329 LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAAR 508
PL+ GV+ + E AFKDV A LV MPRK GMERK+L+ N RI KEQ AL A
Sbjct: 80 FPLVKGVVASNKTEVAFKDVECAILVAGMPRKVGMERKELIGINTRIMKEQALALKNFAN 139
Query: 509 KDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 688
V+VLVV NPANTNAL+ + A I + T +TRLDQNRA +Q+A+K+ V+DV
Sbjct: 140 PHVRVLVVANPANTNALVVANNA-GIDVKQITCLTRLDQNRAIAQIASKLNCKVEDVSDA 198
Query: 689 IIWGNHSSTQFPE 727
+WGNHS Q P+
Sbjct: 199 FVWGNHSEKQCPD 211
>UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 360
Score = 207 bits (506), Expect = 3e-52
Identities = 97/179 (54%), Positives = 125/179 (69%)
Frame = +2
Query: 188 QIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANP 367
++ YSL++++ASG + GP QPV LHL+D+ M L GVVME+ DCA PL+ G++ T N
Sbjct: 51 KLGYSLIFRVASGEMLGPNQPVILHLIDLPFAMAALNGVVMEIQDCAFPLVQGIVATDNQ 110
Query: 368 EEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPAN 547
FKDV A +VGA PR GMER DLL N +IF E G+ ++ A +D+KV+VVGNP N
Sbjct: 111 SVGFKDVNYALMVGAKPRGPGMERGDLLKDNGKIFTETGKYINDHASRDIKVVVVGNPCN 170
Query: 548 TNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
TN LI + IPKENFTAMTRLD NRAQ QLA K+GV D++++ I+GNHS T P
Sbjct: 171 TNCLILANQIKDIPKENFTAMTRLDHNRAQHQLADKLGVHTSDIRKIAIFGNHSPTMVP 229
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 207 bits (505), Expect = 3e-52
Identities = 105/195 (53%), Positives = 132/195 (67%)
Frame = +2
Query: 143 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
K + I V VTGAAGQI Y+ L + +G FG ++ + L LLD+ +L+GV +EL D
Sbjct: 41 KENDEINVCVTGAAGQIGYAFLPLLLTGQCFGDKK-INLRLLDVPQAESILQGVELELQD 99
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
A PLL + +N F+DV A +G PRK GMERKDLL N IFK+QGQALD
Sbjct: 100 GAYPLLKSIKTGSNESILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTV 159
Query: 503 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 682
A+K K LVV NPANTN LI ++ A SIPK+NF+A+TRLD NRA SQ+A K G + DVK
Sbjct: 160 AKKTCKSLVVANPANTNCLILAETAKSIPKQNFSALTRLDHNRAISQIALKAGCSITDVK 219
Query: 683 RVIIWGNHSSTQFPE 727
VIIWGNHS+TQ+P+
Sbjct: 220 NVIIWGNHSTTQYPD 234
Score = 37.1 bits (82), Expect = 0.60
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 765 KSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
K + + IND+AYL AF+ VQKRG V+
Sbjct: 243 KRIRQFINDEAYLNNAFIERVQKRGGEVL 271
>UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Rep:
Malate dehydrogenase - Mastigamoeba balamuthi
(Phreatamoeba balamuthi)
Length = 382
Score = 201 bits (490), Expect = 2e-50
Identities = 100/195 (51%), Positives = 129/195 (66%), Gaps = 2/195 (1%)
Frame = +2
Query: 149 AEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIA--PMMGVLEGVVMELAD 322
A P+ V +TG AGQIAYSL + IA G + G QPV L LLD+ E VVMEL D
Sbjct: 44 AAPLHVTLTGGAGQIAYSLAFLIARGQMLGLYQPVVLRLLDLPRPEKQRAQEAVVMELKD 103
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
CA LL V+ TA+P EAF LVG+ PR G R+DLLA N IFK QG+A+
Sbjct: 104 CAFGLLRDVVATADPREAFAGAHVVVLVGSSPRAAGQLRRDLLAQNAAIFKAQGKAVSDY 163
Query: 503 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 682
A DV+VLVV NPANTN L+ S+ AP+IP+ + + MTRLD NR+++Q+A ++GV ++V
Sbjct: 164 ADPDVRVLVVANPANTNCLVFSRCAPNIPRTHVSCMTRLDHNRSKAQIAERVGVETRNVH 223
Query: 683 RVIIWGNHSSTQFPE 727
I+WGNHS TQ+P+
Sbjct: 224 NAIVWGNHSGTQYPD 238
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 198 bits (484), Expect = 1e-49
Identities = 102/178 (57%), Positives = 126/178 (70%)
Frame = +2
Query: 200 SLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAF 379
+L ++IA G + G ++ VFLH L+I M LEG VMEL DCA P +AG++ T EEAF
Sbjct: 1 ALTFRIAKGDLCGDRK-VFLHHLEIPFGMKALEGCVMELQDCAFPNVAGIVWTDKIEEAF 59
Query: 380 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 559
KDV AFLVG+ PRK+GM+R DLLA N IF QG+AL A+KDVKVLVVGNPANTN L
Sbjct: 60 KDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDVKVLVVGNPANTNCL 119
Query: 560 ICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPECF 733
I AP++ K+N+ AMTRLD NR LAAK GV + V VI+WGNHS+TQ P+ +
Sbjct: 120 IAQASAPNLSKKNWCAMTRLDHNRMVGALAAKFGVTPEKVHNVIVWGNHSNTQVPDAY 177
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 196 bits (479), Expect = 5e-49
Identities = 97/194 (50%), Positives = 131/194 (67%), Gaps = 1/194 (0%)
Frame = +2
Query: 146 MAEPI-RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
M +P+ RV ++GAAGQI YS+L++IA+G + G QPV + +L++ + EGV MEL D
Sbjct: 1 MTKPVLRVCISGAAGQICYSVLFRIAAGDMLGYDQPVHIVMLEVPAALKAAEGVAMELVD 60
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
CA PLL+G T++ EAFKDV L GA PRK GMER +LL+ N IF+ QG A+++
Sbjct: 61 CAFPLLSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQIQGAAINEH 120
Query: 503 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 682
A+ ++LV+GNPANTNAL+ S IPK N TAM+RLD NRA Q+A K+GV +
Sbjct: 121 AKPTCRILVIGNPANTNALVLSTQLTKIPKTNVTAMSRLDHNRAVGQVAGKLGVRTNRIS 180
Query: 683 RVIIWGNHSSTQFP 724
V + GNHS+T P
Sbjct: 181 NVWVAGNHSNTMVP 194
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 195 bits (475), Expect = 1e-48
Identities = 98/194 (50%), Positives = 130/194 (67%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 325
M +P+ V+VTGAAGQI Y L ++IA+G +FG ++ V LHLL+I+P M LE VVMEL DC
Sbjct: 1 MTQPLHVLVTGAAGQIGYVLAFRIANGDLFG-ERDVVLHLLEISPAMKALEAVVMELHDC 59
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
P L V+ T++ EEAF+DV AFLVG+ P+K + D N I+ E G+AL A
Sbjct: 60 TFPHLLHVIGTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFA 119
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
+ VKVLV+G P NTNAL+ A ++ +NF AMTRLD NRA +A K+GV V +
Sbjct: 120 KPTVKVLVIGMPTNTNALVAMTAAVNLSPKNFCAMTRLDHNRAVYSIAQKLGVHHSKVYK 179
Query: 686 VIIWGNHSSTQFPE 727
V+IWGN SS+Q P+
Sbjct: 180 VVIWGNRSSSQIPD 193
>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
precursor; n=62; cellular organisms|Rep: Malate
dehydrogenase [NADP], chloroplast precursor - Zea mays
(Maize)
Length = 432
Score = 195 bits (475), Expect = 1e-48
Identities = 102/190 (53%), Positives = 126/190 (66%)
Frame = +2
Query: 158 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 337
+ V V+GAAG I+ LL+++ASG VFG QP+ L LL LEGV MEL D PL
Sbjct: 90 VNVAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPL 149
Query: 338 LAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDV 517
L V +P F+DV A L+GA PR GMER LL N +IF +QG+AL+ A ++
Sbjct: 150 LREVSIGIDPYVVFQDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRND 209
Query: 518 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 697
+VLVVGNP NTNALIC K AP+IP +NF A+TRLD+NRA+ QLA K GV V V IW
Sbjct: 210 EVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIW 269
Query: 698 GNHSSTQFPE 727
GNHS+TQ P+
Sbjct: 270 GNHSTTQVPD 279
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 194 bits (474), Expect = 2e-48
Identities = 98/192 (51%), Positives = 127/192 (66%)
Frame = +2
Query: 152 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 331
E +RV VTG GQIAY+ L+ +A G VFG + V L + D+ L GV MEL D A
Sbjct: 5 EVVRVAVTGGKGQIAYNFLFALAHGDVFGVDRGVDLRIYDVPGTERALSGVRMELDDGAY 64
Query: 332 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
PLL + T + +AF + AAFL+GA+PR GMER DLL N +IF QG AL+ AA++
Sbjct: 65 PLLHRLRVTTSLNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR 124
Query: 512 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
D K+ VVGNP NTN I K+AP + ++NF AM RLDQNR S LA + VP+++V RV+
Sbjct: 125 DAKIFVVGNPVNTNCWIAMKHAPRLHRKNFHAMLRLDQNRMHSMLAHRAEVPLEEVSRVV 184
Query: 692 IWGNHSSTQFPE 727
IWGNHS+ Q P+
Sbjct: 185 IWGNHSAKQVPD 196
>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 339
Score = 194 bits (473), Expect = 3e-48
Identities = 94/190 (49%), Positives = 127/190 (66%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 325
M EP RV++TGAAGQI Y L + IASG ++G ++PV LHL DI L + MEL DC
Sbjct: 1 MVEPARVLITGAAGQIGYVLSHWIASGELYG-ERPVILHLFDIPVAQNRLTALTMELQDC 59
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
A P LAG + T PE+AFKD+ AFLV ++P K G R DL+ +N IFK G+ L + A
Sbjct: 60 AFPHLAGYVATTEPEQAFKDIDCAFLVASVPMKSGQIRSDLIGSNSIIFKNTGEWLSQYA 119
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
+ VKVLV+GNP NTNA I +A ++ ENF++++ LDQNRA +A K+GV V D+
Sbjct: 120 KPTVKVLVIGNPDNTNAEIALLHAKNLKPENFSSLSLLDQNRAYHAIAEKLGVKVTDLHD 179
Query: 686 VIIWGNHSST 715
+++WGNH +
Sbjct: 180 IVVWGNHGES 189
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 185 bits (451), Expect = 1e-45
Identities = 88/192 (45%), Positives = 122/192 (63%)
Frame = +2
Query: 152 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 331
E +++ +TG AG +A + + SG VFG Q L LL++ + LEG+ M++ DCA
Sbjct: 5 EELKIAITGGAGNLASAFYPLLGSGQVFGSTQKFSLQLLELPEKLQELEGIKMQIQDCAF 64
Query: 332 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
PLL V +++P AFKD A +GAMPRK GMER DLL N IF +QGQ L++ A+
Sbjct: 65 PLLNNVTVSSDPAIAFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKS 124
Query: 512 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
VKVLVV NP+NTN + IP++NFT++ +LD NR S LA + + +K+VI
Sbjct: 125 TVKVLVVANPSNTNCATLAHQCTKIPQQNFTSLMQLDHNRCVSTLAREANTTIDQIKKVI 184
Query: 692 IWGNHSSTQFPE 727
IWGNHS TQ+P+
Sbjct: 185 IWGNHSLTQYPD 196
>UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Rep:
Malate dehydrogenase - Trypanosoma cruzi
Length = 332
Score = 176 bits (429), Expect = 5e-43
Identities = 93/190 (48%), Positives = 120/190 (63%), Gaps = 1/190 (0%)
Frame = +2
Query: 161 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
+VVV+GAAG++ Y+LL IA G + GP Q + L+LLDI M LEG+ EL DCA PLL
Sbjct: 9 KVVVSGAAGKVGYALLPLIAGGRMLGPNQHLQLNLLDIEAAMKCLEGIRAELMDCAFPLL 68
Query: 341 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 520
V+ T P AF++V A L G+ P K G R+DLL N IF E G+ L + A KD
Sbjct: 69 DRVVITHQPAVAFENVDIAILCGSFPAKPGTLRRDLLQKNAAIFSEHGRLLGELASKDCH 128
Query: 521 VLVVGNPANTNALICSKYA-PSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 697
V VVGNP NTNAL+ + I +N +A+TRLD NR+ + +A + V+DVK IIW
Sbjct: 129 VCVVGNPVNTNALVLLNASNGKIKPKNVSALTRLDHNRSLALVAERANAHVRDVKNCIIW 188
Query: 698 GNHSSTQFPE 727
GNHS TQ P+
Sbjct: 189 GNHSGTQVPD 198
Score = 37.9 bits (84), Expect = 0.35
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +3
Query: 771 VSEIINDDAYLKGAFVTTVQKRGAAVI 851
V E I DDAYL G F+TTVQ+RG +I
Sbjct: 209 VREAIKDDAYLDGEFMTTVQQRGYEII 235
>UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase).; n=1;
Takifugu rubripes|Rep: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase). -
Takifugu rubripes
Length = 382
Score = 175 bits (427), Expect = 9e-43
Identities = 91/135 (67%), Positives = 104/135 (77%), Gaps = 1/135 (0%)
Frame = +2
Query: 143 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
+ AEPIRV+VTGAAGQIAYSLL+ IA G VFG QP+ L LLDI M+ VLEGVVMEL D
Sbjct: 90 RQAEPIRVLVTGAAGQIAYSLLFSIAKGDVFGKDQPIILLLLDITAMLPVLEGVVMELQD 149
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
CALPLL ++ T E AFKD+ AA LVG+MPRKEGMERKDLL ANV IFK QG AL+K
Sbjct: 150 CALPLLRDIIATDMEEVAFKDLDAAILVGSMPRKEGMERKDLLKANVAIFKSQGSALEKF 209
Query: 503 ARKDVKVLV-VGNPA 544
++K VKV + G PA
Sbjct: 210 SKKTVKVAMRCGVPA 224
Score = 48.8 bits (111), Expect = 2e-04
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +2
Query: 641 QLAAKIGVPVKDVKRVIIWGNHSSTQFPECFECCXYCWRRSKICF 775
++A + GVP VK VIIWGNHSSTQ+P+ C CF
Sbjct: 215 KVAMRCGVPATHVKNVIIWGNHSSTQYPDVHHCMVNMSGSELTCF 259
Score = 40.3 bits (90), Expect = 0.065
Identities = 17/34 (50%), Positives = 26/34 (76%)
Frame = +3
Query: 750 VGGAQKSVSEIINDDAYLKGAFVTTVQKRGAAVI 851
+ G++ + + I D+A+LKG F+ TVQ+RGAAVI
Sbjct: 251 MSGSELTCFDAIKDEAWLKGEFIATVQQRGAAVI 284
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 173 bits (422), Expect = 4e-42
Identities = 88/196 (44%), Positives = 124/196 (63%)
Frame = +2
Query: 140 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 319
+ EP+ V++TGAAGQI Y+L + I G +F V LHL D+ M L+G+ MEL
Sbjct: 10 VNRTEPLHVLITGAAGQIGYNLCFLIGRGFLFDCD--VILHLYDLNDM--ALKGLSMELT 65
Query: 320 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 499
DC LP L G++ T AF +V A +V +PRK GM+R DL+ N ++ + G+AL
Sbjct: 66 DCCLPKLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGT 125
Query: 500 AARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 679
+ KDV+V+VV NPANTNA + K IP E+ TA+TRLDQNRA + +A ++G + V
Sbjct: 126 YSNKDVRVVVVANPANTNAYVICK-TSGIPPEHITALTRLDQNRATAFVANEVGCQPEFV 184
Query: 680 KRVIIWGNHSSTQFPE 727
+I+WGNHS+T P+
Sbjct: 185 HNIIVWGNHSNTMQPD 200
>UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 166 bits (403), Expect = 8e-40
Identities = 76/195 (38%), Positives = 121/195 (62%)
Frame = +2
Query: 143 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
K P+RV V+ A+G +AY +L + G VFG Q+ V ++LLD L+GV E+ D
Sbjct: 127 KKINPLRVCVSKASGPLAYGMLASLVQGEVFGFQEEVSIYLLDTPENQEALQGVAYEIED 186
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
CA PL GV T++P AFKD + L+ EG ++K+ L ++ ++F++ G+AL+
Sbjct: 187 CAWPLFRGVHITSDPAVAFKDASVVVLLDGKAINEGTDKKEYLLSHAKLFRDYGKALEAH 246
Query: 503 ARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVK 682
A+ D KVL G PAN + I SK+APSI K+NF +++R+++NRA+ +A ++ V +K
Sbjct: 247 AKPDCKVLTAGGPANFSTFIASKFAPSIQKKNFVSLSRIEENRAKGLIAKRLNVNTAGIK 306
Query: 683 RVIIWGNHSSTQFPE 727
+I+WGN +P+
Sbjct: 307 DLIVWGNPGFNHYPD 321
>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
acosta|Rep: Malate dehydrogenase - Hypotrichomonas
acosta
Length = 318
Score = 148 bits (359), Expect = 2e-34
Identities = 74/175 (42%), Positives = 108/175 (61%)
Frame = +2
Query: 203 LLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFK 382
+ ++IA+G + G ++ V LHLL++ + EG+ +EL DCA L + T EEA K
Sbjct: 1 MAFRIANGDLLGNRR-VCLHLLELPVALKACEGLALELEDCAFQNLEKTIVTDKLEEACK 59
Query: 383 DVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALI 562
D+ AFLV ++P K G R +LL N IFK G+AL + A+ V+ LVVGNP N+N L+
Sbjct: 60 DIDIAFLVASVPLKPGEHRVNLLTKNTPIFKAIGEALSEYAKPTVRALVVGNPVNSNCLV 119
Query: 563 CSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPE 727
AP + ENF+ M LD NR+ S++A+ + VP+ V V +WGNH+ TQ P+
Sbjct: 120 AMLNAPKLSAENFSCMCTLDHNRSVSRIASHLKVPIDHVYHVAVWGNHAETQVPD 174
>UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5362-PA - Nasonia vitripennis
Length = 358
Score = 115 bits (277), Expect = 1e-24
Identities = 71/195 (36%), Positives = 104/195 (53%), Gaps = 5/195 (2%)
Frame = +2
Query: 161 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
RVV+T A IA SL Y+I S +FG Q + L L D +L+ V +E+ CA LL
Sbjct: 19 RVVITEATSFIARSLAYRILSDEIFGADQEIVLSLYDSGEQAMLLQTVAIEITACAPNLL 78
Query: 341 AGVLPTANPEEAFKDVAAAFLVGA-----MPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
V+ +++ AF F +G + + ++ +V K+ AL+K A
Sbjct: 79 KDVVYSSDTSLAFAGADWVFFIGKSRDYNFSKSQELQDDPFFIESVLETKKMAIALEKFA 138
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
+ DVK++ +GN T+A + S+YAPSIPK N T +T + Q A S +A K G DVK
Sbjct: 139 KIDVKIITLGN---TSARLISEYAPSIPKNNITGVTLVLQRLAASAIAKKTGRLPSDVKN 195
Query: 686 VIIWGNHSSTQFPEC 730
+IIWG +S + FP C
Sbjct: 196 LIIWGTNSRSVFPYC 210
>UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella
chejuensis KCTC 2396|Rep: Malate dehydrogenase - Hahella
chejuensis (strain KCTC 2396)
Length = 193
Score = 107 bits (256), Expect = 5e-22
Identities = 53/99 (53%), Positives = 66/99 (66%)
Frame = +2
Query: 431 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 610
M+R L N IF EQG+AL K A+ VK LVVGNPANTNALI A +P F+A+
Sbjct: 1 MDRMQQLQENPSIFVEQGKALGKVAKDTVKTLVVGNPANTNALIAWANARYLPHHQFSAL 60
Query: 611 TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPE 727
RLD NRA L+ KIG+ + +KR+ IWGNH+ST FP+
Sbjct: 61 MRLDHNRALGFLSRKIGINPRRIKRLTIWGNHASTLFPD 99
>UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble); n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble) - Monodelphis domestica
Length = 655
Score = 99.1 bits (236), Expect = 1e-19
Identities = 60/188 (31%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = +2
Query: 143 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
+M P++V +TGA+ Y L+ +ASG VFG ++ + ++LL L G+VME D
Sbjct: 261 EMINPLQVWITGASCPTCYHLIPILASGEVFGLEEEISINLLSSTYNEDNLRGLVMESED 320
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
ALPLL + EAF + ++ + E +D + I + G +DK
Sbjct: 321 LALPLLRNISLCTEINEAFLEAHVIVILNDIIEDESEPLEDRIRDRFPICQLYGSLIDKN 380
Query: 503 ARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 679
A ++VKV+V G N + ++ PS+ N A+ + +N A++ LA K+ V
Sbjct: 381 ANENVKVIVAGKTFLNLTTSLIIQHTPSVNPRNIIAVAMIVENEAKAMLARKLKTLPSYV 440
Query: 680 KRVIIWGN 703
K VIIWGN
Sbjct: 441 KDVIIWGN 448
>UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1;
Branchiostoma floridae|Rep: Putative uncharacterized
protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 522
Score = 95.1 bits (226), Expect = 2e-18
Identities = 55/196 (28%), Positives = 102/196 (52%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 KMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
+ ++P+ V V AA AY +L + +G + ++ + LHL D + L+G+ ME+ D
Sbjct: 127 RQSKPLHVCVINAARSPAYHVLPSLVNGKILREEE-IALHLHDSEENLEKLKGLEMEVFD 185
Query: 323 CALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKA 502
+ P L + T + AF++ A ++ + + + V +K +A+++
Sbjct: 186 LSFPFLKEISVTTDLPTAFQNAHIAIVLDDFDQGGKEDAIGDMETKVSFYKRVAEAINQT 245
Query: 503 ARKDVKVLVVGN-PANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 679
A KD++VLV G P N+ I + PSIP++N A+ ++ + +A+S LA ++ V V
Sbjct: 246 ASKDIRVLVAGTGPLNSLVSILIDHTPSIPRQNIAAVAQVKERQAKSLLAKRLTVNSAGV 305
Query: 680 KRVIIWGNHSSTQFPE 727
VI+WGN T + +
Sbjct: 306 CDVIVWGNVGGTTYTD 321
>UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 553
Score = 93.5 bits (222), Expect = 7e-18
Identities = 61/191 (31%), Positives = 94/191 (49%), Gaps = 3/191 (1%)
Frame = +2
Query: 140 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 319
+ + P++V +T ++ IAY ++ +IA G V G V + LL +EG ME+
Sbjct: 120 LSRSTPLQVCITNSSSPIAYHMVNEIARGDVLGHDNEVSIRLLTKPEDKDYVEGQCMEVF 179
Query: 320 DCALPLLAGVLPTANPEEAFKDVAAAFLVG--AMPRKEGMERKDLLAANVRIFKEQGQAL 493
D A PLL GV + A V A + + +E + + F G+ L
Sbjct: 180 DLACPLLRGVKVYTDATAALTGVHVAVFLDEFCLMEEENAKLGGVSQEGCAQFALYGRIL 239
Query: 494 DKAARKDVKVLVVG-NPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPV 670
++ A +DVKVL+ G N +AL+ AP I ++N RL +NRA++ +A KI V
Sbjct: 240 NQYAEQDVKVLIGGRGKLNFSALMLKHNAPRIARQNIIITPRLQENRAKAAIARKINVNT 299
Query: 671 KDVKRVIIWGN 703
V +IIWGN
Sbjct: 300 AGVADLIIWGN 310
>UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21;
Amniota|Rep: Malate dehydrogenase 1B - Homo sapiens
(Human)
Length = 518
Score = 86.6 bits (205), Expect = 8e-16
Identities = 56/190 (29%), Positives = 91/190 (47%), Gaps = 1/190 (0%)
Frame = +2
Query: 155 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 334
P++V +T A+ Y+L+ + SG VFG + + L D L+ +V+E D A P
Sbjct: 131 PLQVWITSASAPACYNLIPILTSGEVFGMHTEISITLFDNKQAEEHLKSLVVETQDLASP 190
Query: 335 LLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKD 514
+L V EEAF+ ++ KE +D L + V + + G ++K A +
Sbjct: 191 VLRSVSICTKVEEAFRQAHVIVVLDDSTNKEVFTLEDCLRSRVPLCRLYGYLIEKNAHES 250
Query: 515 VKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
V+V+V G N ++ +YAP I N A+ + A++ LA K+ +K VI
Sbjct: 251 VRVIVGGRTFVNLKTVLLMRYAPRI-AHNIIAVALGVEGEAKAILARKLKTAPSYIKDVI 309
Query: 692 IWGNHSSTQF 721
IWGN S +
Sbjct: 310 IWGNISGNNY 319
>UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep:
Zgc:153922 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 447
Score = 79.4 bits (187), Expect = 1e-13
Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 1/193 (0%)
Frame = +2
Query: 140 IKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 319
+K P+ + ++ A + YSL+ + + +F + LHL+D + +L+ + ME
Sbjct: 126 LKSLRPLHIWISSALNPVCYSLIPHLFTPGLFSGLPILSLHLMDTSGSEEMLQALKMETV 185
Query: 320 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 499
D A+P L N E+ KD A F GQ ++
Sbjct: 186 DLAIPRLHEPAGEYNDEQNDKDQVAEH-----------------------FHRYGQLIET 222
Query: 500 AARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKD 676
A+KDV+VLV G+ N + + APSI NF AMT + A++QLA K+ V D
Sbjct: 223 NAQKDVRVLVAGDFFINMKCSLLIENAPSIDSRNFVAMTTQLEYEARTQLAQKLSVKTSD 282
Query: 677 VKRVIIWGNHSST 715
+ VI+WGN S +
Sbjct: 283 ITNVIVWGNISGS 295
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 71.7 bits (168), Expect = 2e-11
Identities = 57/182 (31%), Positives = 82/182 (45%)
Frame = +2
Query: 161 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
++ + GAAG I S + Q A+ P L L D P LEGV E+ C L
Sbjct: 8 KLTIVGAAGMIG-SNMAQTAAMMRLTPN----LCLYD--PFAVGLEGVAEEIRHCGFEGL 60
Query: 341 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 520
+ T++ +EA D G PRKEGM R+DLL N I + G+ +
Sbjct: 61 -NLTFTSDIKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKH 119
Query: 521 VLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWG 700
V+++ NPA+ L+ Y+ P + T + LD R QS+LA G+ V +G
Sbjct: 120 VIIIFNPADITGLVTLIYSGLKPSQ-VTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTYG 178
Query: 701 NH 706
H
Sbjct: 179 GH 180
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 65.3 bits (152), Expect = 2e-09
Identities = 57/183 (31%), Positives = 84/183 (45%), Gaps = 1/183 (0%)
Frame = +2
Query: 161 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
++ + GAAG I S + Q A P + L D P LEGV EL CA +
Sbjct: 8 KLTIVGAAGMIG-SNMAQTALMMKLTPN----ICLYD--PYAPALEGVAEELYHCAFEGV 60
Query: 341 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 520
+ T++ +EA G RK GM R+DLL N I + G+ + + DVK
Sbjct: 61 -NLTYTSDIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYC-PDVK 118
Query: 521 -VLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 697
V+VV NPA+ LI YA P + + + LD R Q++L + +P ++ +
Sbjct: 119 HVVVVFNPADITGLIVLLYAGLKPSQ-VSTLAALDSTRLQNELVKYLHIPASEIVNCRTY 177
Query: 698 GNH 706
G H
Sbjct: 178 GGH 180
>UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD
(soluble); n=1; Takifugu rubripes|Rep: malate
dehydrogenase 1B, NAD (soluble) - Takifugu rubripes
Length = 441
Score = 64.9 bits (151), Expect = 3e-09
Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)
Frame = +2
Query: 170 VTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGV 349
++ A + L+ + S VF + +HLLD+ VL + EL AL LL V
Sbjct: 122 ISSALSSTSQFLMSSLISADVFPNISTIDVHLLDLDGDEEVLHHLKNELEHQALHLLHQV 181
Query: 350 LPTANPEEAFKDVAAAFLVGAM------PRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
+ E+AF+ L+ + E +K + A ++E G+ +D +K
Sbjct: 182 TIHTDLEQAFQKADVIILLDELWCDDIATVDERELKKQKIDAISERYREYGRLIDTQTKK 241
Query: 512 DVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 688
+VKV+V G N + Y SI A+ +N A++ +A K+ V DV+ V
Sbjct: 242 EVKVIVSGESFVNLRCSLLLDYTHSIHSHQIVALATQLENEARAIVAKKLNVRPADVRDV 301
Query: 689 IIWGNHSST 715
I+WGN S +
Sbjct: 302 IVWGNISGS 310
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 59.3 bits (137), Expect = 1e-07
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Frame = +2
Query: 371 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANT 550
E D + + +PRK GM R DLL N RI + + + K A V V+VV NP +
Sbjct: 83 EVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAV-VIVVSNPLDE 141
Query: 551 NALICSKYAPSIPKENFTAMT-RLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPE 727
+ ++ PK LD R +A ++GVP++ V R + G+H T P
Sbjct: 142 MTAL-TQLVTGFPKNRVMGQAGMLDTARFSHFVAEELGVPIRAV-RTLTLGSHGDTMVPV 199
Query: 728 CFEC 739
+C
Sbjct: 200 PSQC 203
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 59.3 bits (137), Expect = 1e-07
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 3/159 (1%)
Frame = +2
Query: 257 LHLLDIAPMMGVLEGVVMELADCA--LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 430
L L D+ P G+ +G ++L + L + +L T N E KD + + RKEG
Sbjct: 28 LILYDVVP--GIPQGKALDLKHFSTILGVNRNILGT-NQIEDIKDADIIVITAGVQRKEG 84
Query: 431 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 610
M R+DL+ N +I K +++ K V+ V NP + + K++ ++P E M
Sbjct: 85 MTREDLIGVNGKIMKSVAESVKLHCSK-AFVICVSNPLDIMVNVFHKFS-NLPHEKICGM 142
Query: 611 TR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
LD +R S +A K+ V +DV VI+ G H P
Sbjct: 143 AGILDTSRYCSLIADKLKVSAEDVNAVIL-GGHGDLMVP 180
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 58.0 bits (134), Expect = 3e-07
Identities = 61/205 (29%), Positives = 89/205 (43%), Gaps = 7/205 (3%)
Frame = +2
Query: 131 YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 310
YG K+ +V V GAAG I L I + LHL DIA + +GV
Sbjct: 75 YG-FKINASYKVAVLGAAGGIGQPLSLLIKMSPLVST-----LHLYDIANV----KGVAA 124
Query: 311 ELADCALPLLAGVLPTANPEE---AFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQ 481
+L+ C P + V P E KDV + +PRK GM R DL N I K
Sbjct: 125 DLSHCNTP--SQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTL 182
Query: 482 GQALDKAARKDVKVLVVGNPANTN----ALICSKYAPSIPKENFTAMTRLDQNRAQSQLA 649
+A+ + + + ++ NP N+ A + K PK+ F +T LD RA + ++
Sbjct: 183 VEAVAENC-PNAFIHIISNPVNSTVPIAAEVLKKKGVYDPKKLF-GVTTLDVVRANTFVS 240
Query: 650 AKIGVPVKDVKRVIIWGNHSSTQFP 724
K + + DV +I G+ T P
Sbjct: 241 QKKNLKLIDVDVPVIGGHAGITILP 265
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 58.0 bits (134), Expect = 3e-07
Identities = 36/118 (30%), Positives = 56/118 (47%)
Frame = +2
Query: 371 EAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANT 550
E K + +PR+EGM R+DLL N++I K+ A+ + A KD ++VV NP +T
Sbjct: 84 EELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYA-KDSIIIVVSNPVDT 142
Query: 551 NALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
K P+ LD R ++ + KIG+ D+ R ++ G H P
Sbjct: 143 LTYATIKLTGFEPRRVIGMAGVLDSARFKNFVKEKIGISNADI-RTLVLGTHGDLMVP 199
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 56.4 bits (130), Expect = 9e-07
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 374 AFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPA 544
+ KDVA + +V PR G R DL N RI + + A D K+++V NP
Sbjct: 67 SLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIA-PDTKIIMVTNPV 125
Query: 545 NTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
+ + KY+ P + F T LD R +S +A+ V V +V II G H + P
Sbjct: 126 DVMTCVALKYSGLKPNQVFGLGTHLDSMRLKSLIASYFKVHVSEVHTRII-GEHGDSMVP 184
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 56.0 bits (129), Expect = 1e-06
Identities = 54/197 (27%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 146 MAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADC 325
MA P ++ + GA GQI +L + +A + + L DIA G EG +++A+
Sbjct: 1 MARP-KIALIGA-GQIGGTLAHLVALKELGD------VVLFDIAE--GTPEGKALDIAES 50
Query: 326 ALPLLAGVLPTANPEEAFKDVAAA---FLVGAMPRKEGMERKDLLAANVRIFKEQGQALD 496
G +++ D+A A + +PRK GM R DLL N+++ K G+ +
Sbjct: 51 GPS--EGFDAKLKGTQSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIR 108
Query: 497 KAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVK 673
A D V+ + NP + +++ +P M LD R + LA + V +K
Sbjct: 109 DNA-PDAFVICITNPLDAMVWALQQFS-GLPANKVCGMAGVLDSARFRHFLAEEFNVSMK 166
Query: 674 DVKRVIIWGNHSSTQFP 724
DV ++ G H T P
Sbjct: 167 DVTAFVL-GGHGDTMVP 182
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%)
Frame = +2
Query: 359 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 538
+N KD + +PRK GM R DLLA N +I + G+A+ K + V+ + N
Sbjct: 217 SNDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAI-KQYCPNAFVICITN 275
Query: 539 PANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 715
P + I + +P M LD R ++ L+ ++ V V D+ ++ G H T
Sbjct: 276 PLDVMVYILREKC-GLPPHKVCGMAGVLDSARLRTFLSERLNVSVDDI-HALVMGGHGDT 333
Query: 716 QFP 724
P
Sbjct: 334 MVP 336
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 52.8 bits (121), Expect = 1e-05
Identities = 35/108 (32%), Positives = 50/108 (46%)
Frame = +2
Query: 401 LVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAP 580
L +PRK R DL N RI K + + + A + + +LVV NP + + KY+
Sbjct: 79 LTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAI-LLVVTNPVDIMTTVALKYSG 137
Query: 581 SIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
+P F T LD R ++ LA V V ++ II G H T P
Sbjct: 138 MMPHRVFGLGTHLDSMRLKACLAEFFNVHVSEIHTRII-GEHGDTMVP 184
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 52.4 bits (120), Expect = 2e-05
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 3/195 (1%)
Frame = +2
Query: 149 AEPIRVVVTGAA---GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELA 319
++P++VV+ GA AY+LL A+ + L+D+ EG VM+L
Sbjct: 10 SKPVKVVIVGAGYVGSTTAYTLLMNRAAAEIV---------LIDVDK--DKTEGEVMDLV 58
Query: 320 DCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDK 499
A P L A E K + L +K G R +L +N IFKE + +
Sbjct: 59 HAA-PFLHQTRIWAGDYEDCKGASVIILTAGANQKPGQSRMELAQSNWGIFKEIVPKVVQ 117
Query: 500 AARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDV 679
A D +LV NP + K++ + T LD R +L + + + +
Sbjct: 118 HASPDALLLVSANPVDVMTYAAVKFSGFPAHSVIGSGTSLDSARFAGELGKHLNIDPRSL 177
Query: 680 KRVIIWGNHSSTQFP 724
V+I G H ++ P
Sbjct: 178 HAVVI-GEHGESELP 191
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 52.0 bits (119), Expect = 2e-05
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 1/123 (0%)
Frame = +2
Query: 359 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 538
AN A + + +PRK GM R DLL N+++ ++ G + K A + V+ + N
Sbjct: 63 ANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYA-PEAFVICITN 121
Query: 539 PANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 715
P + K++ +P M LD R + L+ + V V+DV ++ G H +
Sbjct: 122 PLDAMVWALQKFS-GLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVL-GGHGDS 179
Query: 716 QFP 724
P
Sbjct: 180 MVP 182
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 51.6 bits (118), Expect = 3e-05
Identities = 63/204 (30%), Positives = 93/204 (45%), Gaps = 20/204 (9%)
Frame = +2
Query: 158 IRVVVTGAAGQIAY--SLLYQIASGAVFGPQQPVF-LHLLDIAPMMGVLEGVVMELADCA 328
+RV V GAAG I SLL + V G L L D+A L GV +L+
Sbjct: 24 VRVAVLGAAGGIGQPLSLLLKTQLAQVLGDANASLELALYDVAA--DALAGVAADLSHVN 81
Query: 329 LPL-LAGVLPTANP-EEAFKDV---AAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQA 490
P+ ++ +P++ EEA ++ A+ ++ A +PRK GM R DL+ N I K +
Sbjct: 82 TPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKG 141
Query: 491 LDKAA-RKDVKVLVVGNPANTNALIC---------SKYAPSIPKE-NFTAMTRLDQNRAQ 637
+ A + V VLV+ NP N+ + +K AP E +T+LD RA
Sbjct: 142 IAGACDLEKVFVLVISNPVNSLVPVMVRQLIRHAEAKQAPHAGVERRVFGVTQLDMVRA- 200
Query: 638 SQLAAKIGVPVKDVKRVIIWGNHS 709
S +G +V V + G HS
Sbjct: 201 SAFVRSLGELGNEVPSVPVIGGHS 224
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 51.6 bits (118), Expect = 3e-05
Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 1/127 (0%)
Frame = +2
Query: 347 VLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVL 526
V P E + + PR+ GM R+DLL AN+RI + + A D V+
Sbjct: 73 VTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYA-PDAIVI 131
Query: 527 VVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGN 703
VV NP + + K + PK M LD R ++ ++ ++ V KD+ +I G
Sbjct: 132 VVTNPVDVMTYVAYKLL-NFPKNRVMGMAGVLDSARFKTFISEELMVSPKDIHAYVI-GG 189
Query: 704 HSSTQFP 724
H P
Sbjct: 190 HGDEMVP 196
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 50.4 bits (115), Expect = 6e-05
Identities = 48/187 (25%), Positives = 85/187 (45%), Gaps = 3/187 (1%)
Frame = +2
Query: 158 IRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPL 337
+++ V GA G + S+ Y +A V + L+DI + + + + A C +
Sbjct: 1 MKISVIGA-GNVGASIAYALAMRGVCDE-----IALVDIFGDVARAKAIDIAQAGC---V 51
Query: 338 LAGVLPTANPEEAFKDVAAAFLV---GAMPRKEGMERKDLLAANVRIFKEQGQALDKAAR 508
G L TA ++ F + A+ +V PRKEG R+DLL N ++ K+ Q + K A
Sbjct: 52 FCGCLSTAGGDD-FALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAP 110
Query: 509 KDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRV 688
+ V++V NP + +Y+ LD R + ++A+ + KDV
Sbjct: 111 NAI-VIIVTNPLDVMVWTVLRYSGFDRSRVIGMAGELDSARCRYEIASLKDISAKDVSAK 169
Query: 689 IIWGNHS 709
++ G H+
Sbjct: 170 VL-GAHN 175
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 48.8 bits (111), Expect = 2e-04
Identities = 53/205 (25%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Frame = +2
Query: 137 NIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHL-LDIAPM-MGVLEGVVM 310
N + E +++ V GAAG I SL + S A F H+ L + + + G
Sbjct: 40 NAQEKEILKISVLGAAGGIGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAA 99
Query: 311 ELADCALPLLAGV-LP---TANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKE 478
+L+ P+ P + + + + +PRK GM R DL+ N +I K
Sbjct: 100 DLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKS 159
Query: 479 QGQALDK-AARKDVKVLVVGNPAN------TNALICS-KYAPSIPKENFTAMTRLDQNRA 634
G+ + K V VLV+ NP N TN LI S S + +T+LD R+
Sbjct: 160 LGEDIAKYCDLNKVHVLVISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVRS 219
Query: 635 QSQLAAKIGVPVKDVKRVIIWGNHS 709
+ + G + + G HS
Sbjct: 220 STFVQQLNGFKSNTSPVIPVIGGHS 244
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 47.6 bits (108), Expect = 4e-04
Identities = 44/194 (22%), Positives = 78/194 (40%), Gaps = 1/194 (0%)
Frame = +2
Query: 161 RVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
++ + G +G + + + GA+ + + L DI GV + A +P+L
Sbjct: 4 KIAIIGGSGNVGSHIAFL---GAMRHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPIL 60
Query: 341 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVK 520
+ N E + + PR M R DLL N I +E + + A + +
Sbjct: 61 ---IKGCNSYEEIAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSL- 116
Query: 521 VLVVGNPANTNALICSKYAPSIPKENFTAMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIW 697
++VV NP + L+ +++ KE M LD R + +G K ++ +I
Sbjct: 117 LIVVSNPLDAMCLVAKQWS-KFEKERVIGMAGILDSARLTYESKVMLGDFNKHIQSYVI- 174
Query: 698 GNHSSTQFPECFEC 739
G+HS P C
Sbjct: 175 GSHSDDMLPLLRHC 188
>UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to
tetratricopeptide repeat domain 21B; n=1; Apis
mellifera|Rep: PREDICTED: similar to tetratricopeptide
repeat domain 21B - Apis mellifera
Length = 1491
Score = 47.2 bits (107), Expect = 6e-04
Identities = 32/93 (34%), Positives = 48/93 (51%)
Frame = +2
Query: 131 YGNIKMAEPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVM 310
Y IK E + +VT +IA S LY+I + VFG Q VF+ L +++ LE + +
Sbjct: 1214 YPRIKK-EILEKLVTDGTTEIARSFLYRILTDDVFGKNQCVFVSLYELSTKTMFLESLAI 1272
Query: 311 ELADCALPLLAGVLPTANPEEAFKDVAAAFLVG 409
EL + LL+G+ + N E FKD +G
Sbjct: 1273 ELYSFSPKLLSGISYSNNVFE-FKDADVVICIG 1304
>UniRef50_A2Q2G7 Cluster: Putative uncharacterized protein; n=1;
Medicago truncatula|Rep: Putative uncharacterized
protein - Medicago truncatula (Barrel medic)
Length = 165
Score = 47.2 bits (107), Expect = 6e-04
Identities = 27/62 (43%), Positives = 34/62 (54%)
Frame = +2
Query: 185 GQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTAN 364
GQI +L IA G + G Q V LH+LDI P + L+GV MEL D + V +AN
Sbjct: 24 GQIGDALAPMIARGMMLGTNQHVILHMLDIEPTLEALKGVKMELIDVDVAAAGYVDKSAN 83
Query: 365 PE 370
E
Sbjct: 84 IE 85
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 45.6 bits (103), Expect = 0.002
Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 2/158 (1%)
Frame = +2
Query: 257 LHLLDIAPMMGVLEGVVMELADC--ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 430
LHL+ + G V++++D A + + +A+ E + G +PR
Sbjct: 29 LHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVYGSRIVVITAG-VPRTAD 87
Query: 431 MERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM 610
M+R DL N RI + + + + A + +LVV NP + + +Y+ P F
Sbjct: 88 MDRDDLAFKNGRIVADYARQIARFAPDSI-ILVVTNPVDVMTYVALRYSGFHPSRVFGLG 146
Query: 611 TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
LD R ++ +A V V +V +I G H P
Sbjct: 147 NHLDSLRLKNYMARHFNVHVSEVHTRVI-GQHGPYMVP 183
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 44.8 bits (101), Expect = 0.003
Identities = 34/139 (24%), Positives = 61/139 (43%)
Frame = +2
Query: 263 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 442
L D+ P + + A AL + +L T N ++ + PRK GM R+
Sbjct: 31 LYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDD-ISGADIVVITAGKPRKPGMSRR 89
Query: 443 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 622
DL N +I + + L K K ++V NP + A + KY+ + + +++
Sbjct: 90 DLFIDNAKIMIDLAKKLPK-KNKGAMYIMVANPVDMMASVFMKYS---GENTISTGNQVE 145
Query: 623 QNRAQSQLAAKIGVPVKDV 679
R +S +A K+ +P +V
Sbjct: 146 TMRMRSYIAKKLNIPAYEV 164
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 43.6 bits (98), Expect = 0.007
Identities = 39/153 (25%), Positives = 65/153 (42%)
Frame = +2
Query: 263 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 442
L+DIA + V E + + A + ++ A+ K + + RK GM R
Sbjct: 30 LVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGAD-YSLLKGSEIIVVTAGLARKPGMTRL 88
Query: 443 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 622
DL N I K+ + + + A + K+LVV NP + I K + E F +LD
Sbjct: 89 DLAHKNAGIIKDIAKKIVENAPES-KILVVTNPMDVMTYIMWKESGKPRNEVFGMGNQLD 147
Query: 623 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQF 721
R + +L ++++R I G H + F
Sbjct: 148 SQRLKERL---YNAGARNIRRAWIIGEHGDSMF 177
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 43.6 bits (98), Expect = 0.007
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 1/116 (0%)
Frame = +2
Query: 380 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 559
KD + +P+K G R DL+ N +IFK+ + + + + L+ NP +
Sbjct: 72 KDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGI-FLIATNPVDILTY 130
Query: 560 ICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
+ K + +PKE T LD R + L + V ++V I+ G H T+ P
Sbjct: 131 VTWKES-GLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIV-GEHGDTELP 184
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 43.2 bits (97), Expect = 0.009
Identities = 47/190 (24%), Positives = 83/190 (43%), Gaps = 1/190 (0%)
Frame = +2
Query: 155 PIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALP 334
P +V V G G++ + Y +A V G + V L+D P G+ +GV+ ++ A
Sbjct: 5 PYKVAVIGT-GRVGATFAYTMA--IVPGVARMV---LVDAVP--GLSKGVMEDIKHAAAV 56
Query: 335 LLAGVLPTANPEEAFKDVAAAFLVGA-MPRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
+ A + + + A A ++ A PRK M R+DL N +I ++ G L +
Sbjct: 57 FRRSIQVEAYDDVSKVENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKL-RDRNP 115
Query: 512 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
+V+ NP + +I S + T T LD R +S ++ + P+ + +
Sbjct: 116 GAFYMVITNPVDVMTMILSDVIGNKGTVIGTG-TSLDTYRFRSAVSELLNEPIAAIDGYV 174
Query: 692 IWGNHSSTQF 721
+ G H F
Sbjct: 175 V-GEHGEEAF 183
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 43.2 bits (97), Expect = 0.009
Identities = 51/189 (26%), Positives = 80/189 (42%), Gaps = 2/189 (1%)
Frame = +2
Query: 164 VVVTGAAGQ-IAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCALPLL 340
+V GA G IAYS+L Q L L+DI +EG VM+L +P +
Sbjct: 25 IVGAGAVGMAIAYSMLIQNTFDE---------LVLVDIDRRK--VEGEVMDLVH-GIPFV 72
Query: 341 AGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQ-GQALDKAARKDV 517
+ A + V + ++EG R L+ NV IF+ G+ ++ +
Sbjct: 73 EPSVVRAGTLADCRGVDVVVITAGARQREGETRLSLVQRNVEIFRGLIGEIMEHCP--NA 130
Query: 518 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIW 697
+LVV NP + + K A P + T LD R + LA ++ V + + II
Sbjct: 131 ILLVVSNPVDVMTYVAMKLAGLPPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYII- 189
Query: 698 GNHSSTQFP 724
G H ++ P
Sbjct: 190 GEHGDSEVP 198
>UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein
NCU04826.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU04826.1 - Neurospora crassa
Length = 1422
Score = 42.7 bits (96), Expect = 0.012
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = -1
Query: 534 PTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAV 355
PTT T+ + ++ + ++ A R ++PS G +PT+ +A S SS A
Sbjct: 160 PTTAASTTTASHRTRPSSSEIDSKSTTASRRTSAVPSSTGASPTKPSARVSSTTSSTTAA 219
Query: 354 GRTPAKSGRAQSANSMTTPSSTP 286
R PA S S T S TP
Sbjct: 220 ARKPASSSTVSPRTSTTGVSRTP 242
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 42.7 bits (96), Expect = 0.012
Identities = 40/141 (28%), Positives = 57/141 (40%)
Frame = +2
Query: 296 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFK 475
EG M+L A PL + KD A + +K G R DLL AN+ IFK
Sbjct: 59 EGEAMDLNHAA-PLSHETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFK 117
Query: 476 EQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAK 655
E + + K KD +LV NP + K + + T +D R Q +
Sbjct: 118 EILREVTKYT-KDAILLVATNPVDVLTYATLKLTGFPAERVIGSGTIIDTARFQYLIGKL 176
Query: 656 IGVPVKDVKRVIIWGNHSSTQ 718
G+ + V II G H ++
Sbjct: 177 YGLDPQSVNADII-GEHGDSE 196
>UniRef50_A0T7L1 Cluster: Putative uncharacterized protein; n=1;
Burkholderia ambifaria MC40-6|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 543
Score = 42.3 bits (95), Expect = 0.016
Identities = 37/184 (20%), Positives = 82/184 (44%), Gaps = 2/184 (1%)
Frame = -3
Query: 706 MVSPDDYSLNIFNWYSNFSSKLGLSPVLIKTSHGSEIFFWNRWSIFRTY*SICIGW--VA 533
+V+P L+ + + +L V+++ H E+ R R + + +G VA
Sbjct: 356 VVAPHGELLDRCDRLARLRGELRQRAVVVEAQHCGEVLL--RQIRCRLHGDVRVGVRRVA 413
Query: 532 NNKDLHIFTSRFVQSLALLFEDAHISSKKILPLHTFLSGHXXXXXXXXXXXXXXFRICCR 353
+++ LH+ FVQ AL ED + +++L H + RI
Sbjct: 414 DDQHLHVAARDFVQRGALDREDLGVRRQQVLAFHALRARTCADQQSDVCILECHLRIVGD 473
Query: 352 KNPSQKWQSTVGQLHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTS 173
+ ++ + + +LH + F R ++++++DRL+ ++ + R+ ++ VC+L+
Sbjct: 474 HDAREQRERAIVELHHDAFDGGLGLREVEQLQDDRLVLAEQVAVRDAEQQGVCDLTCGAG 533
Query: 172 YNNS 161
N+
Sbjct: 534 DGNA 537
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 41.5 bits (93), Expect = 0.028
Identities = 42/161 (26%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Frame = +2
Query: 263 LLDIAPMMGVLEGVVMELADCALPLLAGV-LPTANPEEAFKDVAAAFLVGAMPRKEGME- 436
L D+ P M G ++L A GV + AN + + + + + G
Sbjct: 38 LFDVVPNMPA--GKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95
Query: 437 ----RKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFT 604
RKDLL NV+I +E G A+ K V+ + NP + + + A +P
Sbjct: 96 QEWSRKDLLPVNVKILREVGAAI-KQFCPHAFVINITNPLDV-MVAALREAAGLPAARVC 153
Query: 605 AMTR-LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
M LD R + LA ++GV +DV+ +++ G H P
Sbjct: 154 GMAGVLDSARFRRLLADRLGVSPRDVQAMVL-GVHGDNMVP 193
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 41.5 bits (93), Expect = 0.028
Identities = 40/190 (21%), Positives = 78/190 (41%)
Frame = +2
Query: 152 EPIRVVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELADCAL 331
+PI++ + GA G + S LY + + ++DI P +G + D +
Sbjct: 2 KPIKIALIGA-GNVGNSFLYAAMNQGLASEYG-----IIDINPDFA--DGNAFDFEDASA 53
Query: 332 PLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARK 511
L + + + KD + P+K G R +L+A N+RI +E + ++
Sbjct: 54 SLPFPISVSRYEYKDLKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFS 113
Query: 512 DVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVI 691
+ + +V NP + + ++ + T LD R Q +A + V V+ +
Sbjct: 114 GISI-IVANPVDIITRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVSPNSVQAYV 172
Query: 692 IWGNHSSTQF 721
+ G H + F
Sbjct: 173 M-GEHGDSSF 181
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 40.3 bits (90), Expect = 0.065
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 1/144 (0%)
Frame = +2
Query: 296 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFL-VGAMPRKEGMERKDLLAANVRIF 472
EG M+L L+ G+ A A + L GA + R LL N IF
Sbjct: 43 EGEAMDLMH-GQQLVGGITCRAVEYAALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIF 101
Query: 473 KEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAA 652
+E LDK A + V V NP + IC + + + T LD R ++ L
Sbjct: 102 REIIIQLDKHAPNAILV-VATNPVDVLTYICQELSSRPNRRILGTGTLLDTARFRALLGR 160
Query: 653 KIGVPVKDVKRVIIWGNHSSTQFP 724
GV + V I+ G H ++ P
Sbjct: 161 HYGVDPRSVHAYIL-GEHGDSEVP 183
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 40.3 bits (90), Expect = 0.065
Identities = 38/152 (25%), Positives = 65/152 (42%)
Frame = +2
Query: 263 LLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERK 442
++D+ P +++ V++LAD A + + + EEA + GA R EG R
Sbjct: 34 IVDVNP--DIVQAQVLDLADAA-SISHTPIRAGSAEEAGQADIVVITAGAKQR-EGEPRT 89
Query: 443 DLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 622
L+ N R+ + + + R D +LVV NP + I + P + + T LD
Sbjct: 90 KLIERNFRVLQSIIGGM-QPIRPDAVILVVANPVDILTHIAKTLSGLPPNQVIGSGTYLD 148
Query: 623 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQ 718
R + L V + V ++ G H +Q
Sbjct: 149 TTRLRVHLGDVFDVNPQSVHAFVL-GEHGDSQ 179
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 39.1 bits (87), Expect = 0.15
Identities = 34/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 326 ALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAA 505
A P+ G D L +K G R DLL N IF+E + +AA
Sbjct: 48 AAPVSHGTRVWHGGHSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAA 107
Query: 506 RKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKR 685
D +LV NP + + ++ AP P + T LD R + +A GV
Sbjct: 108 -PDAVLLVTSNPVDLLTDLATQLAPGQPV--IGSGTVLDSARFRHLMAQHAGVDGTHAHG 164
Query: 686 VIIWGNHSSTQ 718
++ G H ++
Sbjct: 165 YVL-GEHGDSE 174
>UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4;
Euteleostomi|Rep: L-lactate dehydrogenase - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 38.7 bits (86), Expect = 0.20
Identities = 36/157 (22%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
Frame = +2
Query: 257 LHLLDIAPMMGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGME 436
L L+D+ M L+G +M+L +L L + + + + ++EG
Sbjct: 49 LALVDV--MEDRLKGELMDLQHGSLFLKTSKIVADKDYSVTANSRLVVVTAGVRQQEGES 106
Query: 437 RKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM-T 613
R +L+ NV +FK + K + + ++VV NP + + K + +PK T
Sbjct: 107 RLNLVQRNVNVFKSIIPQIIKYS-PNCTLIVVSNPVDVLTYVTWKLS-GLPKHRVIGSGT 164
Query: 614 RLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
LD R + +A ++G+ ++ G H T P
Sbjct: 165 NLDSARFRYLMAERLGIHASSFNGWVL-GEHGDTSVP 200
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 37.9 bits (84), Expect = 0.35
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 1/143 (0%)
Frame = +2
Query: 296 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMP-RKEGMERKDLLAANVRIF 472
EG ++L A + + + ++ KD ++P R R ++ N+ I
Sbjct: 39 EGDALDLTHAAALVDSNIKISSGEIADSKDSDVIIFTASVPFRYPNQTRLEMGIDNMPIL 98
Query: 473 KEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAA 652
++ L KA+ + V++V NP + A + PK T +D R ++ L+
Sbjct: 99 RDWMPGLAKASPNAI-VVMVSNPVDALAYETIRLTGFDPKRVIGTGTLVDSIRYRALLST 157
Query: 653 KIGVPVKDVKRVIIWGNHSSTQF 721
++ + +D+ R I G H TQF
Sbjct: 158 ELKIHAQDI-RAYILGEHGDTQF 179
>UniRef50_Q9HHJ2 Cluster: Vng6368h; n=1; Halobacterium
salinarum|Rep: Vng6368h - Halobacterium salinarium
(Halobacterium halobium)
Length = 141
Score = 37.5 bits (83), Expect = 0.46
Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Frame = -1
Query: 534 PTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAA-TSLKASSGFA 358
PT F RA++ + T + +RS S P+ P+ + A AS+
Sbjct: 3 PTMPRFPCSRASMMERSRKLSSSTTYSRKRSTASRPTPATTQPSTSSIAWKKTPASTSTH 62
Query: 357 VGRTPAKSGRAQSANSMTTPSSTPIIGAISR 265
TP++ GR SAN +PSSTP + I +
Sbjct: 63 SPPTPSRQGRPSSANRNRSPSSTPALSRICK 93
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 37.5 bits (83), Expect = 0.46
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Frame = +2
Query: 380 KDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNAL 559
KD + + K G R D++ N++IF+ + K + + +LVV NP +
Sbjct: 72 KDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSI-LLVVSNPVDILTY 130
Query: 560 ICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQ 718
I K + PKE T LD +R + L+ + ++V II G H ++
Sbjct: 131 ITYKLS-GFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNVHTYII-GEHGDSE 182
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 37.1 bits (82), Expect = 0.60
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 3/112 (2%)
Frame = +2
Query: 413 MPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICS---KYAPS 583
+PRK GM+R+DL+ N + E A + + + NP N I + K +
Sbjct: 105 LPRKPGMKREDLVDVNASVACEVAFAASEVC-PGAMLAFITNPINVIVPIVATILKAKGT 163
Query: 584 IPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPECFEC 739
+T LD RAQ+ +A + V + V +I G+ T P +C
Sbjct: 164 YDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQC 215
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 36.7 bits (81), Expect = 0.80
Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 3/127 (2%)
Frame = +2
Query: 368 EEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGNPAN 547
E A + MPR GM+R L+AAN + + A+ A+ + + + NP N
Sbjct: 85 ESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPR-AHLAFITNPVN 143
Query: 548 TNALICSKYA---PSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQ 718
++ + +T LD R++ + + + DV +I G+ T
Sbjct: 144 MIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITI 203
Query: 719 FPECFEC 739
P +C
Sbjct: 204 LPLISQC 210
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 36.3 bits (80), Expect = 1.1
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 308 MELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQ 487
M++AD + V+ KD + +PR G R D+L +V ++
Sbjct: 47 MDIADSVSFFNSSVIVRCGDYSDCKDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVS 106
Query: 488 ALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKEN-FTAMTRLDQNRAQSQLA 649
L+K K + ++ + NPA+ A K A +PK F+ T LD R + +A
Sbjct: 107 NLNKIEIKGI-IITITNPADIIADFVRK-ATGLPKNRVFSTGTSLDTARMRRTVA 159
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 36.3 bits (80), Expect = 1.1
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 1/121 (0%)
Frame = +2
Query: 359 ANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVLVVGN 538
A E KD + K G R DL+ N IFK + K + K + +LVV N
Sbjct: 64 AGDYEDTKDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSI-LLVVSN 122
Query: 539 PANTNALICSKYAPSIPKENFTAM-TRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSST 715
P + + K + P+E T LD +R + L + V++V I+ G H +
Sbjct: 123 PVDILTYVTYKLS-GFPQERVIGSGTVLDTSRFRYLLGEHFKIDVRNVHTYIL-GEHGDS 180
Query: 716 Q 718
+
Sbjct: 181 E 181
>UniRef50_Q6DXR3 Cluster: Predicted protein; n=3; eurosids II|Rep:
Predicted protein - Gossypium hirsutum (Upland cotton)
(Gossypium mexicanum)
Length = 253
Score = 35.9 bits (79), Expect = 1.4
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Frame = +2
Query: 263 LLDIAPMMGVLEGV--VMELADCA-LPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGM 433
L+++A + GVL G+ VM+ ADC L L GVL NP ++ +A ++ RK G
Sbjct: 173 LVEVA-LKGVLAGLERVMKAADCVRLKALKGVLDVLNPSQSLDFLAGICMLQIQIRKWGQ 231
Query: 434 ERKDLLAANVRIFKE 478
R + +N I E
Sbjct: 232 NRDNQKGSNPIILGE 246
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 35.9 bits (79), Expect = 1.4
Identities = 28/126 (22%), Positives = 47/126 (37%)
Frame = +2
Query: 347 VLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQALDKAARKDVKVL 526
++ AN + PR+ GM R DLL AN ++ + + ++ V V+
Sbjct: 55 IVRVANEPSDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVM 114
Query: 527 VVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNH 706
V NP + K + P + LD R S + K+G + ++ G H
Sbjct: 115 -VSNPLDAMVYTAIKESGLSPLQVLGMAGILDSARMASFIFEKLGYGSDQIVASVM-GGH 172
Query: 707 SSTQFP 724
P
Sbjct: 173 GDDMVP 178
>UniRef50_P19980 Cluster: Malate dehydrogenase; n=5; Bacteria|Rep:
Malate dehydrogenase - Phenylobacterium immobile
Length = 25
Score = 35.9 bits (79), Expect = 1.4
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +2
Query: 155 PIRVVVTGAAGQIAYSLLYQIA 220
PIRV VTGAAG I Y LL++IA
Sbjct: 4 PIRVAVTGAAGNIGYHLLFRIA 25
>UniRef50_A7P2B9 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 199
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/53 (35%), Positives = 25/53 (47%)
Frame = +2
Query: 164 VVVTGAAGQIAYSLLYQIASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
+V G G + IA G QP+ LH+LDI P VL G V+ + D
Sbjct: 101 LVAVGMGGGTSSGEAPMIARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 153
Score = 33.5 bits (73), Expect = 7.4
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +2
Query: 215 IASGAVFGPQQPVFLHLLDIAPMMGVLEGVVMELAD 322
IA G QP+ LH+LDI P VL G V+ + D
Sbjct: 13 IARRGRLGADQPMILHMLDIPPAAEVLNGGVVAITD 48
>UniRef50_O97299 Cluster: Putative uncharacterized protein
MAL3P7.37; n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein MAL3P7.37 - Plasmodium
falciparum (isolate 3D7)
Length = 1542
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = -3
Query: 310 HDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNSYRFSHFD 140
HDN + Y H +N K E +R+ + K ++N +K V +T NN+Y + D
Sbjct: 204 HDNNYNYFHVGKNEKMKERERINKKKKIGKKNNRRKHVLR-KNNTDGNNNYNDDNND 259
>UniRef50_Q9BYR4 Cluster: Keratin-associated protein 4-3; n=53;
Mammalia|Rep: Keratin-associated protein 4-3 - Homo
sapiens (Human)
Length = 195
Score = 35.5 bits (78), Expect = 1.8
Identities = 49/171 (28%), Positives = 59/171 (34%), Gaps = 8/171 (4%)
Frame = +1
Query: 163 SCCNW-CCRTNCILTS--LSNCVWSSFWTSTTCLPPPS*YCAYDGCT*RCCHGVGRLCSA 333
SCC CCRT C S +S+C S S+ C P C C CC + C
Sbjct: 28 SCCQTTCCRTTCCRPSCCISSCCRPSCCISSCCKPS---CCRTTCCRPSCC--ISSCCRP 82
Query: 334 TFGWGSSYSKS*RSFQRXXXXFPSWCYAQKGRYGEEGSSCC--*CAHLQRARPGFGQSGS 507
+ S S R PS C + R SSCC C RP S
Sbjct: 83 SCCISSCCKP---SCCRTTCCRPSCCISSCCRPSCCISSCCKPSCCQTTCCRPSCCISSC 139
Query: 508 *R--CEGPCCWQPSQYKCSNMF*ICSIYSKR-KFHCHDSS*SKQGSVPTCC 651
R C P C +P+ S C + S R F C + P CC
Sbjct: 140 YRPQCCQPSCCRPACCISSCCHPSCCVSSCRCPFSCPTTCCRTTCFHPICC 190
>UniRef50_Q827S2 Cluster: Putative aminodeoxychorismate lyase; n=2;
Streptomyces|Rep: Putative aminodeoxychorismate lyase -
Streptomyces avermitilis
Length = 605
Score = 35.1 bits (77), Expect = 2.4
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +2
Query: 284 MGVLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLV-GAMPRKEGMERKDLLAAN 460
+GV +G +A+ L G+ AN ++ KD FL P +GM+ KD+L
Sbjct: 383 LGVKKGTTKGVAEKEWSTL-GLPDWANTDKDIKDPLEGFLYPSTYPVSKGMKPKDVLKEM 441
Query: 461 VRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNR 631
V + K++ AL A+ K L + NP + + K +F + R+ NR
Sbjct: 442 VNLAKDKYAALGIQAK--AKDLNLKNPLQVLTVASLVQSEGNSKNDFEKVARVVYNR 496
>UniRef50_Q2RQ78 Cluster: Putative uncharacterized protein; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: Putative
uncharacterized protein - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 696
Score = 35.1 bits (77), Expect = 2.4
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = -1
Query: 666 GTPILAASWD*ALF*SRRVMAVKFSFGIDGAYLEHIRAFVLAGLPTTRTFTSLRAALSKA 487
GTP++A W AL RR +FG+D A + A+V L R RAA +
Sbjct: 605 GTPVVA--WQGALMRDRRAAFWCAAFGLDEAVVRTAEAYVRQALAFGRDRAKRRAAAERL 662
Query: 486 WPCSLKMRTLAARRSFLSIPSFLGIAP 406
C+ R R ++ SFL P
Sbjct: 663 --CAAAPRLFGDPRGLSALVSFLADGP 687
>UniRef50_A3BI71 Cluster: Putative uncharacterized protein; n=7;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 571
Score = 35.1 bits (77), Expect = 2.4
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +1
Query: 286 GCT*RCCHGVGRLCSATFGWGSSY 357
GC CC GVG + S T GWGSSY
Sbjct: 539 GCGGGCCGGVGFVESPTCGWGSSY 562
>UniRef50_Q8IEN1 Cluster: Putative uncharacterized protein MAL13P1.39;
n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein MAL13P1.39 - Plasmodium
falciparum (isolate 3D7)
Length = 6088
Score = 35.1 bits (77), Expect = 2.4
Identities = 21/56 (37%), Positives = 29/56 (51%)
Frame = -3
Query: 313 LHDNTFKYTHHRRNIKKVEEDRLLRSKNCSRRNLIKK*VCNLSGSTSYNNSYRFSH 146
L DN FK + R NIKK+ E+R SKN +N KK + N+ Y + S+
Sbjct: 1044 LQDNYFKKLYDR-NIKKMMEERENASKNIFAKNKKKKIILNILKKVYYRYEHNLSN 1098
>UniRef50_Q9P5T7 Cluster: Related to glucan 1, 4-alpha-glucosidase;
n=2; Neurospora crassa|Rep: Related to glucan 1,
4-alpha-glucosidase - Neurospora crassa
Length = 701
Score = 35.1 bits (77), Expect = 2.4
Identities = 29/93 (31%), Positives = 43/93 (46%)
Frame = +2
Query: 311 ELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFKEQGQA 490
EL +C P++ TA PE + AAA A RKE M +LA V + + +A
Sbjct: 383 ELEECGSPVVPW---TARPELSNAVAAAAAAAAAAERKEAMVGVPVLAVPVPPSRARTRA 439
Query: 491 LDKAARKDVKVLVVGNPANTNALICSKYAPSIP 589
+A + V+ +V GN A A + P +P
Sbjct: 440 QTQA--QSVQTVVTGNKAAAVAAAVALQIPQLP 470
>UniRef50_Q8YTB2 Cluster: Valine-pyruvate aminotransferase; n=9;
Cyanobacteria|Rep: Valine-pyruvate aminotransferase -
Anabaena sp. (strain PCC 7120)
Length = 450
Score = 34.7 bits (76), Expect = 3.2
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +2
Query: 518 KVLVVGNPANTNALICSKYAPSIPKENFTAMTRL-DQNRAQSQLAAKIGVPVKDVKRVII 694
K+ + P N LI S YAP P NFT M+ + +N +K G+P + + I
Sbjct: 232 KIAALAAPYNVPVLIDSAYAPPFPALNFTDMSLIFGENILHCTSLSKAGLPGERIGIAI- 290
Query: 695 WGNHSSTQFPECFE 736
GN Q E F+
Sbjct: 291 -GNERLIQVLESFQ 303
>UniRef50_A7NQN6 Cluster: Extracellular solute-binding protein
family 5 precursor; n=1; Roseiflexus castenholzii DSM
13941|Rep: Extracellular solute-binding protein family 5
precursor - Roseiflexus castenholzii DSM 13941
Length = 564
Score = 34.7 bits (76), Expect = 3.2
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 15/111 (13%)
Frame = +2
Query: 287 GVLEGVVMELADCALPLLAGVLPTANP--EEAFK---DVAAAFL--VGAMPRKEGMERKD 445
G++E V + + A L+ V P P E+ ++ + AA L G +P +G+ KD
Sbjct: 344 GIIESVYFNMVEPAYGPLSRVFPEYEPALEQMYEYNPEKAAQLLEEAGWLPGPDGVRVKD 403
Query: 446 LLAANVRIFKEQG--------QALDKAARKDVKVLVVGNPANTNALICSKY 574
V I + +G QA +A D KVL P+NT A+ KY
Sbjct: 404 GRRLEVTIVENKGWNDWVYVLQANLQAIGFDAKVLTTQGPSNTEAIASGKY 454
>UniRef50_Q1J2E3 Cluster: Peptidase M23B precursor; n=1; Deinococcus
geothermalis DSM 11300|Rep: Peptidase M23B precursor -
Deinococcus geothermalis (strain DSM 11300)
Length = 330
Score = 34.3 bits (75), Expect = 4.3
Identities = 25/59 (42%), Positives = 33/59 (55%)
Frame = -1
Query: 465 RTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSST 289
RT+AAR +PS G+ P RK+AA+S A RTPA + RA S + PS+T
Sbjct: 157 RTVAAR-----LPSSEGVTPDRKSAASS-------AARRTPAATVRAASIRVTSAPSAT 203
>UniRef50_Q869R4 Cluster: Similar to Streptococcus pneumoniae. Cell
wall surface anchor family protein; n=3; Dictyostelium
discoideum|Rep: Similar to Streptococcus pneumoniae. Cell
wall surface anchor family protein - Dictyostelium
discoideum (Slime mold)
Length = 1806
Score = 34.3 bits (75), Expect = 4.3
Identities = 23/61 (37%), Positives = 30/61 (49%)
Frame = -1
Query: 405 TRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTA 226
T AA T+ ++S F TP+ S S +S+TT ST + GA S TG G T
Sbjct: 1220 TTTAATTATPSTSLFGSTTTPSTSS---STSSLTTTPSTGLFGASSSTTPSTGLFGSATT 1276
Query: 225 P 223
P
Sbjct: 1277 P 1277
>UniRef50_UPI0000DD83F5 Cluster: PREDICTED: similar to keratin
associated protein 9.2; n=1; Homo sapiens|Rep:
PREDICTED: similar to keratin associated protein 9.2 -
Homo sapiens
Length = 301
Score = 33.9 bits (74), Expect = 5.6
Identities = 17/54 (31%), Positives = 20/54 (37%), Gaps = 2/54 (3%)
Frame = +1
Query: 154 TYKSCCNWCCRTNCILTSLSNCVWSSFWTSTTCLPPP--S*YCAYDGCT*RCCH 309
T CC+ CC+ C T+ T TTC P C C CCH
Sbjct: 75 TMTHCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPSCCVPSCCQPCCH 128
>UniRef50_A3KPA8 Cluster: LOC568298 protein; n=2; Danio rerio|Rep:
LOC568298 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 258
Score = 33.9 bits (74), Expect = 5.6
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Frame = -1
Query: 534 PTTRT-FTSLRAALSKAWPCSLKMRTLAARRSFL--SIPSFLGIAPTRKAAATSLKASSG 364
PTT+T F S S +P S + LAA + F + + G +P A S A +
Sbjct: 25 PTTQTTFGSSTFTTSSNFPASTP-QALAAPKPFAFGAAGASSGASPFTFGTAASTSAPA- 82
Query: 363 FAVGRTPAKSGRAQ--SANSMTTPSSTPIIGAISR 265
F PA G + S + TTPS+TP+ GA ++
Sbjct: 83 FGTNSQPAFGGVSSGFSFGNTTTPSATPVFGATTQ 117
>UniRef50_Q54HN9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 621
Score = 33.9 bits (74), Expect = 5.6
Identities = 32/117 (27%), Positives = 48/117 (41%)
Frame = -1
Query: 516 TSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAK 337
TS+ W + K L + +S P+ P A +++ ASS TP
Sbjct: 469 TSVVETKKMEWGPADKKSVLPVETTVVSPPTTTTTTPV--APTSNVAASSSSTATATPTT 526
Query: 336 SGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI**RSEYAICPAAPVTT 166
+ Q+A S PS+ S+ PK +P + +S+ A PAAPVTT
Sbjct: 527 TTTTQTAASTNAPSNKKSTTQSSQ---------PKKSPSKVEDKSKTAPTPAAPVTT 574
>UniRef50_Q1JTH9 Cluster: Hyothetical protein; n=4; root|Rep:
Hyothetical protein - Toxoplasma gondii RH
Length = 1821
Score = 33.9 bits (74), Expect = 5.6
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Frame = +1
Query: 61 LFHSSSESAKXXXXXXXXXXXXXXXXYQNG*TYKSC----CNWCCRTNCILTSLSNCVWS 228
LF S S S+ +G ++ SC C+ C ++C +S S C +S
Sbjct: 558 LFSSCSSSSWSGCSFSSCSSSSCSSSSCSGCSFSSCSSSSCSGCSSSSCSSSSWSGCSFS 617
Query: 229 SFWTSTTCLPPPS*YCAYDGCT*RCCHGVGRLCSATFGW-GSSYS 360
S +S++C C++ C+ C G ++ W G S+S
Sbjct: 618 S-CSSSSCSG-----CSFSSCSSSSCSGCSSSSCSSSSWSGCSFS 656
>UniRef50_P58338 Cluster: Ornithine cyclodeaminase 1; n=34;
Proteobacteria|Rep: Ornithine cyclodeaminase 1 -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 329
Score = 33.9 bits (74), Expect = 5.6
Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 5/109 (4%)
Frame = -1
Query: 585 IDGAYLEHIR---AFVLAGLPTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLG 415
+D YL +R A +A +R +S+ A L++ LA R +
Sbjct: 106 LDNGYLTDVRTAAAGAVAARRLSREDSSVAAVFGAGMQARLQLEALALVRPIREARIWAR 165
Query: 414 IAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSM--TTPSSTPIIGA 274
A +AAA +L GFAV A+ + TTPS TP++ A
Sbjct: 166 DAAKAEAAAIALGGKLGFAVKAETDPRAAITGADIIVTTTPSETPVLKA 214
>UniRef50_UPI00006CFE65 Cluster: hypothetical protein
TTHERM_00691510; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00691510 - Tetrahymena
thermophila SB210
Length = 1176
Score = 33.5 bits (73), Expect = 7.4
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Frame = -3
Query: 331 QSTVGQLHDNTFKYTHHRRNIKKVEEDRLLRSKN-CSRRNLIKK*VCNLSGSTSYNNSYR 155
Q ++ Q++ + KY H+ N + EED + SKN S N IK L+ ++ N YR
Sbjct: 66 QQSIQQINQSYNKYVLHQNNQQNDEEDNMNFSKNILSLHNTIKTNQSQLANQSAIQN-YR 124
Query: 154 FS 149
+S
Sbjct: 125 YS 126
>UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep:
Beta-lactamase - Vibrio angustum S14
Length = 318
Score = 33.5 bits (73), Expect = 7.4
Identities = 18/44 (40%), Positives = 26/44 (59%)
Frame = +2
Query: 593 ENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 724
EN T + ++ A+ QL A+IGV V D K ++G HS +FP
Sbjct: 54 ENITVNSAIEH--AEKQLGARIGVSVFDGKGKQLFGYHSDQRFP 95
>UniRef50_Q9P5L4 Cluster: Related to DOS1 protein; n=3;
Sordariomycetes|Rep: Related to DOS1 protein -
Neurospora crassa
Length = 452
Score = 33.5 bits (73), Expect = 7.4
Identities = 18/59 (30%), Positives = 30/59 (50%)
Frame = -1
Query: 450 RRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGA 274
R + +S L IA T+ AA+ + ASSG + + S + S + TTP++ + A
Sbjct: 90 RTTLISRTRALSIATTQAAASAAAAASSGVTAASSSSSSSSSASKDEQTTPTTVKDLSA 148
>UniRef50_Q8PTW7 Cluster: Putative uncharacterized protein; n=1;
Methanosarcina mazei|Rep: Putative uncharacterized
protein - Methanosarcina mazei (Methanosarcina frisia)
Length = 324
Score = 33.5 bits (73), Expect = 7.4
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 7/108 (6%)
Frame = +2
Query: 128 LYGNIKMAEPIRVVVTGAAGQIAYSLLYQIAS--GAVFGPQQPV----FLHLLDIAPMMG 289
L GN+K+ P+ V+ + A + + L +I + AV +PV F +L P+
Sbjct: 215 LLGNLKLLIPLGVIASALASLLYFRGLARIKAQTAAVLSLIEPVSSICFCCILLGEPLQS 274
Query: 290 -VLEGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEG 430
+ G ++ LA AL + + PE+ F+DV A F MP + G
Sbjct: 275 NTVGGCLLILAGAALIGSSTSIQQGIPEKYFRDVWARFFQPYMPLRPG 322
>UniRef50_P20659 Cluster: Protein trithorax; n=4; Drosophila
melanogaster|Rep: Protein trithorax - Drosophila
melanogaster (Fruit fly)
Length = 3726
Score = 33.5 bits (73), Expect = 7.4
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Frame = -1
Query: 504 AALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVGRTPAKSGRA 325
AA KA S RT +A S S G +P + A+S ASSG + G++ AKS A
Sbjct: 157 AASGKA--LSKSSRTFSASTSVTSSGRSSGSSPDGNSGASSDGASSGISCGKSTAKSTEA 214
Query: 324 QSAN-SMTTPSST 289
S + TT + T
Sbjct: 215 SSGKLAKTTGAGT 227
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 33.5 bits (73), Expect = 7.4
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 1/141 (0%)
Frame = +2
Query: 296 EGVVMELADCALPLLAGVLPTANPEEAFKDVAAAFLVGAMPRKEGMERKDLLAANVRIFK 475
EG V +L D A A + T +A +D + +PRK G R DL+ N +I +
Sbjct: 44 EGDVKDLEDVAAFTNATNIHTGEYADA-RDADIVVITAGVPRKPGESRLDLINRNTKILE 102
Query: 476 EQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAM-TRLDQNRAQSQLAA 652
+ + A+ + ++ NP + + + + P+ T LD R + LA
Sbjct: 103 SIVKPV-VASGFNGCFVISSNPVDILTSMTQRLS-GFPRHRVIGTGTSLDTARLRVALAQ 160
Query: 653 KIGVPVKDVKRVIIWGNHSST 715
K+ V V ++ G H +
Sbjct: 161 KLNVATTAVDAAVL-GEHGDS 180
>UniRef50_P35453 Cluster: Homeobox protein Hox-D13; n=47;
Craniata|Rep: Homeobox protein Hox-D13 - Homo sapiens
(Human)
Length = 335
Score = 33.5 bits (73), Expect = 7.4
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Frame = -1
Query: 447 RSFLSIPSFLGI-----APTRKAAATSLKASSGFAVGRTPAKSGRAQSANSMTTPSSTP 286
R FLS P F G A AAA + A+SGFA T ++G + S++S ++ P
Sbjct: 33 RGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARP 91
>UniRef50_UPI0000F21642 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 288
Score = 33.1 bits (72), Expect = 9.8
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 1/115 (0%)
Frame = -1
Query: 555 AFVLAGLPTTRTFT-SLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSL 379
A A PT T + AA + P + T AA + + P+ APT AA +
Sbjct: 92 ASTAAAAPTAPAATPASTAAAAPTAPAATPASTAAAPTAPAATPASTAAAPTAPAATPAS 151
Query: 378 KASSGFAVGRTPAKSGRAQSANSMTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI 214
A++ A PA + +A + P+ST + + P TA +++
Sbjct: 152 TAAAPTAPAVAPAAMPASTAATAPIAPASTAAVSIAAEAIIAATAVAPNTAANSL 206
>UniRef50_Q88SJ4 Cluster: Extracellular protein,
gamma-D-glutamate-meso-diaminopimelate muropeptidase;
n=1; Lactobacillus plantarum|Rep: Extracellular protein,
gamma-D-glutamate-meso-diaminopimelate muropeptidase -
Lactobacillus plantarum
Length = 370
Score = 33.1 bits (72), Expect = 9.8
Identities = 20/88 (22%), Positives = 41/88 (46%)
Frame = -1
Query: 531 TTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSLKASSGFAVG 352
T+ TS + + ++ ++AA+ S S S + + ++ + +ASS
Sbjct: 123 TSAAATSSSTTSASSTSQAVSSSSVAAQSSSTSTASASSVTSSASTSSVASQASSSAVTS 182
Query: 351 RTPAKSGRAQSANSMTTPSSTPIIGAIS 268
++S +QS+ S + SSTP+ + S
Sbjct: 183 SATSQSSASQSSASQASQSSTPVASSTS 210
>UniRef50_A6W575 Cluster: Putative uncharacterized protein; n=1;
Kineococcus radiotolerans SRS30216|Rep: Putative
uncharacterized protein - Kineococcus radiotolerans
SRS30216
Length = 212
Score = 33.1 bits (72), Expect = 9.8
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 9/138 (6%)
Frame = -1
Query: 543 AGLPTTRTFTSLRAALSKAWPCSLKMRTLAARRSFLSIPSFLGIAPTRKAAATSL--KAS 370
A P +T + S A + T A+++ P+ P +K A K +
Sbjct: 71 AAAPAKKTSAPAQKTASSA---PAQKATTPAQKTASPAPAQKATTPAKKTTAKKAAGKKA 127
Query: 369 SGFAVGRTPAKSGRAQSANS--MTTPSSTPIIGAISRRWRKTGC*GPKTAPDAI**R--- 205
+ V TPA + A +A + + TP++TP A +++ K A DA R
Sbjct: 128 APAPVEETPAPAAEAPAAEAPAVETPAATPAKKATAKKAAKKSTPASTAAVDARAVREWA 187
Query: 204 --SEYAICPAAPVTTTLI 157
+ A+ P P++TT+I
Sbjct: 188 AANGIAVAPRGPISTTII 205
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 823,429,296
Number of Sequences: 1657284
Number of extensions: 16725799
Number of successful extensions: 53277
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 50369
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 53170
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 80751996367
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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