Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P28_F_A07
(910 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 134 3e-31
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 134 3e-31
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 134 3e-31
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 134 3e-31
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 134 6e-31
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 126 1e-28
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 109 2e-23
AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1 p... 38 0.067
AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1 p... 38 0.067
AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1 p... 38 0.067
AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1 p... 38 0.067
BC005252-1|AAH05252.1| 300|Homo sapiens geranylgeranyl diphosph... 31 7.6
AL391994-8|CAI13753.1| 300|Homo sapiens geranylgeranyl diphosph... 31 7.6
AF125394-1|AAD43050.1| 300|Homo sapiens gerannylgeranyl pyropho... 31 7.6
AF057698-1|AAG45581.1| 300|Homo sapiens geranylgeranyl pyrophos... 31 7.6
AB019036-1|BAA77251.1| 300|Homo sapiens geranylgeranyl pyrophos... 31 7.6
AB017971-1|BAA75909.1| 300|Homo sapiens geranylgeranyl diphosph... 31 7.6
AB016043-1|BAA76511.1| 300|Homo sapiens GGPP synthase protein. 31 7.6
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 134 bits (325), Expect = 3e-31
Identities = 61/143 (42%), Positives = 95/143 (66%), Gaps = 3/143 (2%)
Frame = +3
Query: 414 PQIGDW---LKKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMF 584
P+IGD LK++L YN +GGK+ RG+T V++++ + +P K +L+ A +GWCVE+
Sbjct: 36 PEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELL 95
Query: 585 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYI 764
QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P Y+
Sbjct: 96 QAFFLVADDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYL 154
Query: 765 KMFELFNETLWRTSMGQHLDHVT 833
+ ELF ++ ++T +GQ LD +T
Sbjct: 155 NLIELFLQSSYQTEIGQTLDLLT 177
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 134 bits (325), Expect = 3e-31
Identities = 69/193 (35%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = +3
Query: 264 WPQLIRYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 434
W + R +S M + EK+ F +++ L + ++ P+IGD L
Sbjct: 55 WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 112
Query: 435 KKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 614
K++L YN +GGK+ RG+T V++++ + +P K +L+ A +GWCVE+ QA+ +V DDI
Sbjct: 113 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 172
Query: 615 MDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYIKMFELFNETL 794
MD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF ++
Sbjct: 173 MDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSS 231
Query: 795 WRTSMGQHLDHVT 833
++T +GQ LD +T
Sbjct: 232 YQTEIGQTLDLLT 244
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 134 bits (325), Expect = 3e-31
Identities = 69/193 (35%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = +3
Query: 264 WPQLIRYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 434
W + R +S M + EK+ F +++ L + ++ P+IGD L
Sbjct: 54 WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 111
Query: 435 KKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 614
K++L YN +GGK+ RG+T V++++ + +P K +L+ A +GWCVE+ QA+ +V DDI
Sbjct: 112 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 171
Query: 615 MDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYIKMFELFNETL 794
MD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF ++
Sbjct: 172 MDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSS 230
Query: 795 WRTSMGQHLDHVT 833
++T +GQ LD +T
Sbjct: 231 YQTEIGQTLDLLT 243
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 134 bits (325), Expect = 3e-31
Identities = 69/193 (35%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = +3
Query: 264 WPQLIRYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 434
W + R +S M + EK+ F +++ L + ++ P+IGD L
Sbjct: 54 WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 111
Query: 435 KKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 614
K++L YN +GGK+ RG+T V++++ + +P K +L+ A +GWCVE+ QA+ +V DDI
Sbjct: 112 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 171
Query: 615 MDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYIKMFELFNETL 794
MD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF ++
Sbjct: 172 MDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSS 230
Query: 795 WRTSMGQHLDHVT 833
++T +GQ LD +T
Sbjct: 231 YQTEIGQTLDLLT 243
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 134 bits (323), Expect = 6e-31
Identities = 61/143 (42%), Positives = 95/143 (66%), Gaps = 3/143 (2%)
Frame = +3
Query: 414 PQIGDW---LKKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMF 584
P+IGD LK++L YN +GGK+ RG+T V++++ + +P K +L+ A +GWCVE+
Sbjct: 29 PEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELL 88
Query: 585 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYI 764
QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P Y+
Sbjct: 89 QAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYL 147
Query: 765 KMFELFNETLWRTSMGQHLDHVT 833
+ ELF ++ ++T +GQ LD +T
Sbjct: 148 NLIELFLQSSYQTEIGQTLDLLT 170
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 126 bits (303), Expect = 1e-28
Identities = 58/143 (40%), Positives = 92/143 (64%), Gaps = 3/143 (2%)
Frame = +3
Query: 414 PQIGDW---LKKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMF 584
P+IGD LK++L YN +GGK+ R +T ++++ + P K +L+ A +GWCVE+
Sbjct: 31 PEIGDAIARLKEVLEYNAIGGKYNRRLTVAVAFRELVDPRKQDADSLQRAWTVGWCVELL 90
Query: 585 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYI 764
QA+ +V DDIMD S RRG CWY++P VG+ A +D+ L+ + ++ LK R P Y+
Sbjct: 91 QAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYL 149
Query: 765 KMFELFNETLWRTSMGQHLDHVT 833
+ ELF ++ ++T +GQ LD +T
Sbjct: 150 NLIELFLQSSYQTEIGQTLDLLT 172
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 109 bits (261), Expect = 2e-23
Identities = 50/143 (34%), Positives = 89/143 (62%), Gaps = 3/143 (2%)
Frame = +3
Query: 414 PQIGDW---LKKMLHYNLVGGKHTRGITTVISYKTIEKPEKVTEHTLKMACKLGWCVEMF 584
P+ GD LK++L YN +GGK+ RG+ +++++ + +P K+ +L+ A +GW ++
Sbjct: 4 PETGDATARLKEVLEYNAIGGKYHRGLMVLVAFRELVEPRKLDADSLQWAPTVGWYAQLL 63
Query: 585 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYI 764
QA+ +V DDIMD S +G WY++ +G+ A ND++L+ + ++ LK R P Y+
Sbjct: 64 QAFFLVADDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYL 122
Query: 765 KMFELFNETLWRTSMGQHLDHVT 833
+ ELF + ++T +GQ LD +T
Sbjct: 123 NLMELFQQNSYQTEIGQTLDLIT 145
>AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1
protein.
Length = 2369
Score = 37.5 bits (83), Expect = 0.067
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Frame = +3
Query: 279 RYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 449
+Y+N A + A KN E +E L ++ LQN +K VP+ IG L + LH
Sbjct: 13 KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72
Query: 450 YNLVGGKHTRGITTV-ISYKTI 512
L GG H + + T I +K I
Sbjct: 73 PALPGGVHRKALETYEIIFKII 94
>AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1
protein.
Length = 2465
Score = 37.5 bits (83), Expect = 0.067
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Frame = +3
Query: 279 RYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 449
+Y+N A + A KN E +E L ++ LQN +K VP+ IG L + LH
Sbjct: 13 KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72
Query: 450 YNLVGGKHTRGITTV-ISYKTI 512
L GG H + + T I +K I
Sbjct: 73 PALPGGVHRKALETYEIIFKII 94
>AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1
protein.
Length = 2369
Score = 37.5 bits (83), Expect = 0.067
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Frame = +3
Query: 279 RYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 449
+Y+N A + A KN E +E L ++ LQN +K VP+ IG L + LH
Sbjct: 13 KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72
Query: 450 YNLVGGKHTRGITTV-ISYKTI 512
L GG H + + T I +K I
Sbjct: 73 PALPGGVHRKALETYEIIFKII 94
>AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1
protein.
Length = 2465
Score = 37.5 bits (83), Expect = 0.067
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Frame = +3
Query: 279 RYKNNSANMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 449
+Y+N A + A KN E +E L ++ LQN +K VP+ IG L + LH
Sbjct: 13 KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72
Query: 450 YNLVGGKHTRGITTV-ISYKTI 512
L GG H + + T I +K I
Sbjct: 73 PALPGGVHRKALETYEIIFKII 94
>BC005252-1|AAH05252.1| 300|Homo sapiens geranylgeranyl diphosphate
synthase 1 protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AL391994-8|CAI13753.1| 300|Homo sapiens geranylgeranyl diphosphate
synthase 1 protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AF125394-1|AAD43050.1| 300|Homo sapiens gerannylgeranyl
pyrophosphate synthase protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AF057698-1|AAG45581.1| 300|Homo sapiens geranylgeranyl
pyrophosphate synthetase protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AB019036-1|BAA77251.1| 300|Homo sapiens geranylgeranyl
pyrophosphate synthase protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AB017971-1|BAA75909.1| 300|Homo sapiens geranylgeranyl diphosphate
synthase protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
>AB016043-1|BAA76511.1| 300|Homo sapiens GGPP synthase protein.
Length = 300
Score = 30.7 bits (66), Expect = 7.6
Identities = 29/100 (29%), Positives = 44/100 (44%)
Frame = +3
Query: 525 KVTEHTLKMACKLGWCVEMFQAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLL 704
KV E L++ ++ EM +++DDI D S +RRG P GI N +
Sbjct: 40 KVPEDKLQIIIEV---TEMLHNASLLIDDIEDNSKLRRGFP--VAHSIYGIPSVINSANY 94
Query: 705 IHSSLFEFLKTNFRTNPNYIKMFELFNETLWRTSMGQHLD 824
++ E + T +P+ +K LF L GQ LD
Sbjct: 95 VYFLGLEKVLT--LDHPDAVK---LFTRQLLELHQGQGLD 129
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,678,242
Number of Sequences: 237096
Number of extensions: 2759353
Number of successful extensions: 4683
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4493
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4676
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11770329464
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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