Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_pT_K19
(758 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U20352-1|AAC16436.1| 334|Homo sapiens malate dehydrogenase prot... 171 2e-42
D55654-1|BAA09513.1| 334|Homo sapiens cytosolic malate dehydrog... 171 2e-42
CR457405-1|CAG33686.1| 334|Homo sapiens MDH1 protein. 171 2e-42
BC001484-1|AAH01484.1| 334|Homo sapiens malate dehydrogenase 1,... 171 2e-42
AC016734-1|AAY14893.1| 334|Homo sapiens unknown protein. 171 2e-42
BC088356-1|AAH88356.1| 518|Homo sapiens malate dehydrogenase 1B... 59 2e-08
BC033509-1|AAH33509.1| 283|Homo sapiens MDH1B protein protein. 54 6e-07
AC008269-1|AAX93274.1| 283|Homo sapiens unknown protein. 54 6e-07
BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein. 31 6.0
BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein. 31 6.0
AB046838-1|BAB13444.1| 1415|Homo sapiens KIAA1618 protein protein. 31 6.0
>U20352-1|AAC16436.1| 334|Homo sapiens malate dehydrogenase
protein.
Length = 334
Score = 171 bits (417), Expect = 2e-42
Identities = 83/158 (52%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = -2
Query: 757 GVPVKDVKRVIXWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRG 578
GV DVK VI WGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RG
Sbjct: 172 GVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRG 231
Query: 577 AAVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVT 404
AAVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV
Sbjct: 232 AAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVV 291
Query: 403 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 290
+ N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 292 IKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>D55654-1|BAA09513.1| 334|Homo sapiens cytosolic malate
dehydrogenase protein.
Length = 334
Score = 171 bits (417), Expect = 2e-42
Identities = 83/158 (52%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = -2
Query: 757 GVPVKDVKRVIXWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRG 578
GV DVK VI WGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RG
Sbjct: 172 GVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRG 231
Query: 577 AAVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVT 404
AAVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV
Sbjct: 232 AAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVV 291
Query: 403 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 290
+ N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 292 IKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>CR457405-1|CAG33686.1| 334|Homo sapiens MDH1 protein.
Length = 334
Score = 171 bits (417), Expect = 2e-42
Identities = 83/158 (52%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = -2
Query: 757 GVPVKDVKRVIXWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRG 578
GV DVK VI WGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RG
Sbjct: 172 GVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRG 231
Query: 577 AAVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVT 404
AAVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV
Sbjct: 232 AAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVV 291
Query: 403 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 290
+ N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 292 IKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>BC001484-1|AAH01484.1| 334|Homo sapiens malate dehydrogenase 1,
NAD (soluble) protein.
Length = 334
Score = 171 bits (417), Expect = 2e-42
Identities = 83/158 (52%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = -2
Query: 757 GVPVKDVKRVIXWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRG 578
GV DVK VI WGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RG
Sbjct: 172 GVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRG 231
Query: 577 AAVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVT 404
AAVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV
Sbjct: 232 AAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVV 291
Query: 403 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 290
+ N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 292 IKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>AC016734-1|AAY14893.1| 334|Homo sapiens unknown protein.
Length = 334
Score = 171 bits (417), Expect = 2e-42
Identities = 83/158 (52%), Positives = 104/158 (65%), Gaps = 2/158 (1%)
Frame = -2
Query: 757 GVPVKDVKRVIXWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQKRG 578
GV DVK VI WGNHSSTQ+PD ++A + G + V E + DD++LKG FVTTVQ+RG
Sbjct: 172 GVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRG 231
Query: 577 AAVIXXXXXXXXXXXXXXXSDHMRD-WFLGTEDRWVSMGVVSDG-SYGTPRDVVYSFPVT 404
AAVI DH+RD WF E +VSMGV+SDG SYG P D++YSFPV
Sbjct: 232 AAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVV 291
Query: 403 VTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEALD 290
+ N WK VEGL I+DF+R+ +D T KEL EEK+ A +
Sbjct: 292 IKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFE 329
>BC088356-1|AAH88356.1| 518|Homo sapiens malate dehydrogenase 1B,
NAD (soluble) protein.
Length = 518
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 9/158 (5%)
Frame = -2
Query: 739 VKRVIXWGNHSSTQFPDASNA------VAIVGGAQKS--VSEIINDDAYLKGAFVTTVQK 584
+K VI WGN S + D AI G S V +I D ++K FV ++
Sbjct: 305 IKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNLIFDSEWVKREFVAILKN 364
Query: 583 RGAAVIXXXXXXXXXXXXXXXSDHMRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPV 407
+ + ++ W+ G+ VS+G++S+G +G P+ +V+S PV
Sbjct: 365 ----LTTTGRQFGGILAAHSIATTLKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPV 420
Query: 406 TVTNGKWKIVEGLTISDFARQMLDATGKELVEEKQEAL 293
NG W ++ L + + Q++ +L++EK AL
Sbjct: 421 KFENGTWVVLTDLKDVEISEQIMTRMTSDLIQEKLVAL 458
>BC033509-1|AAH33509.1| 283|Homo sapiens MDH1B protein protein.
Length = 283
Score = 54.0 bits (124), Expect = 6e-07
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Frame = -2
Query: 511 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 335
++ W+ G+ VS+G++S+G +G P+ +V+S PV NG W ++ L + + Q++
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231
Query: 334 ATGKELVEEKQEAL 293
+L++EK AL
Sbjct: 232 RMTSDLIQEKLVAL 245
>AC008269-1|AAX93274.1| 283|Homo sapiens unknown protein.
Length = 283
Score = 54.0 bits (124), Expect = 6e-07
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Frame = -2
Query: 511 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 335
++ W+ G+ VS+G++S+G +G P+ +V+S PV NG W ++ L + + Q++
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231
Query: 334 ATGKELVEEKQEAL 293
+L++EK AL
Sbjct: 232 RMTSDLIQEKLVAL 245
>BC040341-1|AAH40341.1| 1063|Homo sapiens KIAA1618 protein.
Length = 1063
Score = 30.7 bits (66), Expect = 6.0
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = -2
Query: 388 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 287
W +EGL+ S F QMLD + + + EKQ L +
Sbjct: 719 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 753
>BC036891-1|AAH36891.1| 1063|Homo sapiens KIAA1618 protein.
Length = 1063
Score = 30.7 bits (66), Expect = 6.0
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = -2
Query: 388 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 287
W +EGL+ S F QMLD + + + EKQ L +
Sbjct: 719 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 753
>AB046838-1|BAB13444.1| 1415|Homo sapiens KIAA1618 protein protein.
Length = 1415
Score = 30.7 bits (66), Expect = 6.0
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = -2
Query: 388 WKIVEGLTISDFARQMLDATG-KELVEEKQEALDV 287
W +EGL+ S F QMLD + + + EKQ L +
Sbjct: 584 WAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSI 618
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,020,554
Number of Sequences: 237096
Number of extensions: 2070207
Number of successful extensions: 3537
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3430
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3527
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9183116696
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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