Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_N08
(725 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC091477-1|AAH91477.2| 314|Homo sapiens Yip1 interacting factor... 162 1e-39
BC014974-1|AAH14974.1| 294|Homo sapiens YIF1B protein protein. 162 1e-39
BC007644-1|AAH07644.1| 310|Homo sapiens YIF1B protein protein. 162 1e-39
AY358965-1|AAQ89324.1| 283|Homo sapiens ADPH3073 protein. 162 1e-39
AF258578-1|AAG23781.1| 283|Homo sapiens PP4519 protein. 162 1e-39
CR456710-1|CAG32991.1| 293|Homo sapiens YIF1 protein. 156 9e-38
BC001299-1|AAH01299.1| 293|Homo sapiens Yip1 interacting factor... 156 9e-38
AF004876-1|AAD01206.1| 293|Homo sapiens 54TMp protein. 153 5e-37
S83365-1|AAB50850.1| 123|Homo sapiens putative Rab5-interacting... 69 2e-11
BC009892-1|AAH09892.2| 162|Homo sapiens YIF1A protein protein. 62 3e-09
M74547-1|AAA36397.1| 935|Homo sapiens p107 protein. 32 1.8
L14812-1|AAA02489.1| 1068|Homo sapiens p107 protein. 32 1.8
BC032247-1|AAH32247.1| 1014|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL391114-2|CAI95152.1| 1014|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL391114-1|CAI95151.1| 1068|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL365505-2|CAI95178.1| 1014|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL365505-1|CAI95177.1| 1068|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL136172-4|CAI95717.1| 1014|Homo sapiens retinoblastoma-like 1 (... 32 1.8
AL136172-3|CAI95716.1| 1068|Homo sapiens retinoblastoma-like 1 (... 32 1.8
>BC091477-1|AAH91477.2| 314|Homo sapiens Yip1 interacting factor
homolog B (S. cerevisiae) protein.
Length = 314
Score = 162 bits (393), Expect = 1e-39
Identities = 70/125 (56%), Positives = 96/125 (76%)
Frame = +1
Query: 349 SPAQISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRK 528
SP ++ L PV +MA+ YG+ LAAQGKE V + + +F+P+++L+YYFAVDT YV RK
Sbjct: 65 SPTPHAAFLADPV-SNMAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRK 123
Query: 529 LMLIVFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSP 708
L L+ FPY H++W V+Y QDTPV PR+D+NAPDLYIP+M ++TYVL+AG LG RFSP
Sbjct: 124 LGLLFFPYLHQDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSP 183
Query: 709 EQIGI 723
+ +G+
Sbjct: 184 DLLGL 188
>BC014974-1|AAH14974.1| 294|Homo sapiens YIF1B protein protein.
Length = 294
Score = 162 bits (393), Expect = 1e-39
Identities = 70/125 (56%), Positives = 96/125 (76%)
Frame = +1
Query: 349 SPAQISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRK 528
SP ++ L PV +MA+ YG+ LAAQGKE V + + +F+P+++L+YYFAVDT YV RK
Sbjct: 62 SPTPHAAFLADPV-SNMAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRK 120
Query: 529 LMLIVFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSP 708
L L+ FPY H++W V+Y QDTPV PR+D+NAPDLYIP+M ++TYVL+AG LG RFSP
Sbjct: 121 LGLLFFPYLHQDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSP 180
Query: 709 EQIGI 723
+ +G+
Sbjct: 181 DLLGL 185
>BC007644-1|AAH07644.1| 310|Homo sapiens YIF1B protein protein.
Length = 310
Score = 162 bits (393), Expect = 1e-39
Identities = 70/125 (56%), Positives = 96/125 (76%)
Frame = +1
Query: 349 SPAQISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRK 528
SP ++ L PV +MA+ YG+ LAAQGKE V + + +F+P+++L+YYFAVDT YV RK
Sbjct: 61 SPTPHAAFLADPV-SNMAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRK 119
Query: 529 LMLIVFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSP 708
L L+ FPY H++W V+Y QDTPV PR+D+NAPDLYIP+M ++TYVL+AG LG RFSP
Sbjct: 120 LGLLFFPYLHQDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSP 179
Query: 709 EQIGI 723
+ +G+
Sbjct: 180 DLLGL 184
>AY358965-1|AAQ89324.1| 283|Homo sapiens ADPH3073 protein.
Length = 283
Score = 162 bits (393), Expect = 1e-39
Identities = 70/125 (56%), Positives = 96/125 (76%)
Frame = +1
Query: 349 SPAQISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRK 528
SP ++ L PV +MA+ YG+ LAAQGKE V + + +F+P+++L+YYFAVDT YV RK
Sbjct: 34 SPTPHAAFLADPV-SNMAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRK 92
Query: 529 LMLIVFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSP 708
L L+ FPY H++W V+Y QDTPV PR+D+NAPDLYIP+M ++TYVL+AG LG RFSP
Sbjct: 93 LGLLFFPYLHQDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSP 152
Query: 709 EQIGI 723
+ +G+
Sbjct: 153 DLLGL 157
>AF258578-1|AAG23781.1| 283|Homo sapiens PP4519 protein.
Length = 283
Score = 162 bits (393), Expect = 1e-39
Identities = 70/125 (56%), Positives = 96/125 (76%)
Frame = +1
Query: 349 SPAQISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRK 528
SP ++ L PV +MA+ YG+ LAAQGKE V + + +F+P+++L+YYFAVDT YV RK
Sbjct: 34 SPTPHAAFLADPV-SNMAMAYGSSLAAQGKELVDKNIDRFIPITKLKYYFAVDTMYVGRK 92
Query: 529 LMLIVFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSP 708
L L+ FPY H++W V+Y QDTPV PR+D+NAPDLYIP+M ++TYVL+AG LG RFSP
Sbjct: 93 LGLLFFPYLHQDWEVQYQQDTPVAPRFDVNAPDLYIPAMAFITYVLVAGLALGTQDRFSP 152
Query: 709 EQIGI 723
+ +G+
Sbjct: 153 DLLGL 157
>CR456710-1|CAG32991.1| 293|Homo sapiens YIF1 protein.
Length = 293
Score = 156 bits (378), Expect = 9e-38
Identities = 66/121 (54%), Positives = 95/121 (78%)
Frame = +1
Query: 361 ISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRKLMLI 540
++ +L P+ ++A+ YG+ +A+ GK+ V +ELH+FV VS+L+Y+FAVDT YV +KL L+
Sbjct: 51 VNHLLGDPMA-NVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLL 109
Query: 541 VFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSPEQIG 720
VFPYTH+ W V+Y +D P+ PR D+NAPDLYIP+M ++TYVLLAG LG+ RFSPE +G
Sbjct: 110 VFPYTHQNWEVQYSRDAPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLG 169
Query: 721 I 723
+
Sbjct: 170 L 170
>BC001299-1|AAH01299.1| 293|Homo sapiens Yip1 interacting factor
homolog A (S. cerevisiae) protein.
Length = 293
Score = 156 bits (378), Expect = 9e-38
Identities = 66/121 (54%), Positives = 95/121 (78%)
Frame = +1
Query: 361 ISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRKLMLI 540
++ +L P+ ++A+ YG+ +A+ GK+ V +ELH+FV VS+L+Y+FAVDT YV +KL L+
Sbjct: 51 VNHLLGDPMA-NVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLL 109
Query: 541 VFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSPEQIG 720
VFPYTH+ W V+Y +D P+ PR D+NAPDLYIP+M ++TYVLLAG LG+ RFSPE +G
Sbjct: 110 VFPYTHQNWEVQYSRDAPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLG 169
Query: 721 I 723
+
Sbjct: 170 L 170
>AF004876-1|AAD01206.1| 293|Homo sapiens 54TMp protein.
Length = 293
Score = 153 bits (372), Expect = 5e-37
Identities = 65/121 (53%), Positives = 94/121 (77%)
Frame = +1
Query: 361 ISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRKLMLI 540
++ +L P+ ++A+ YG+ +A+ GK+ V +ELH+FV VS+L+Y+FAVDT YV +KL L+
Sbjct: 51 VNHLLGDPMA-NVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLL 109
Query: 541 VFPYTHKEWMVKYDQDTPVQPRYDINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSPEQIG 720
VFPYTH+ W V+Y +D P+ PR D+NAPDLYIP+ ++TYVLLAG LG+ RFSPE +G
Sbjct: 110 VFPYTHQNWEVQYSRDAPLPPRQDLNAPDLYIPTKAFITYVLLAGMALGIQKRFSPEVLG 169
Query: 721 I 723
+
Sbjct: 170 L 170
>S83365-1|AAB50850.1| 123|Homo sapiens putative Rab5-interacting
protein protein.
Length = 123
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/69 (46%), Positives = 50/69 (72%), Gaps = 1/69 (1%)
Frame = +1
Query: 361 ISSMLQQPVVQDMAIQYGNQLAAQGKEAVQRELHKFVPVSRLRYYFAVDTRYVIRKLML- 537
++ +L P+ ++A+ YG+ +A+ GK+ V +ELH+FV VS+L+Y+FAVDT YV ++
Sbjct: 42 VNHLLGDPMA-NVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVGQEARAG 100
Query: 538 IVFPYTHKE 564
VFPYTH E
Sbjct: 101 WVFPYTHPE 109
>BC009892-1|AAH09892.2| 162|Homo sapiens YIF1A protein protein.
Length = 162
Score = 61.7 bits (143), Expect = 3e-09
Identities = 25/38 (65%), Positives = 32/38 (84%)
Frame = +1
Query: 610 DINAPDLYIPSMGYVTYVLLAGFMLGLXHRFSPEQIGI 723
D+NAPDLYIP+M ++TYVLLAG LG+ RFSPE +G+
Sbjct: 2 DLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGL 39
>M74547-1|AAA36397.1| 935|Homo sapiens p107 protein.
Length = 935
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 342 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 401
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 402 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 458
>L14812-1|AAA02489.1| 1068|Homo sapiens p107 protein.
Length = 1068
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>BC032247-1|AAH32247.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL391114-2|CAI95152.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL391114-1|CAI95151.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL365505-2|CAI95178.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL365505-1|CAI95177.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL136172-4|CAI95717.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
>AL136172-3|CAI95716.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 32.3 bits (70), Expect = 1.8
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Frame = -3
Query: 633 VQVRGVDVVPGLHWSVLI---VFHHPLLMSIGED--YEH*FPYNISCIDRKIVPQPRDWH 469
V V+ + G+ SVL+ +FH L+ E + + P I + QP ++
Sbjct: 475 VMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFY 534
Query: 468 KLVQFSLHSLLALSRELVAVLNSHVLDYRLLQHRAYLRRGSHWRRKSPSKSKI-TCRSM 295
K+++ + S LSR++V LNS ++ ++L+ A+ + W S +K+ TC +
Sbjct: 535 KVIEVVIRSEEGLSRDMVKHLNS--IEEQILESLAWSHDSALWEALQVSANKVPTCEEV 591
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,802,433
Number of Sequences: 237096
Number of extensions: 2559844
Number of successful extensions: 6017
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 5652
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6014
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -