Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_L13
(725 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial acetoacetyl... 260 5e-69
D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial acetoacetyl... 260 5e-69
AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA acetyltransf... 159 1e-38
BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein. 155 1e-37
AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A acety... 154 3e-37
AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA transferase-... 154 3e-37
S70154-1|AAB30856.1| 397|Homo sapiens cytosolic acetoacetyl-coe... 152 1e-36
BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein. 124 4e-28
BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein. 119 9e-27
BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A acylt... 108 2e-23
D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-C... 107 5e-23
X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA... 75 3e-13
X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRN... 75 3e-13
X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for ... 75 3e-13
BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 75 3e-13
BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 75 3e-13
BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein. 53 6e-11
BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 64 5e-10
D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase b... 64 6e-10
BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 64 6e-10
BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 64 6e-10
BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 64 6e-10
AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein. 64 6e-10
X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase pr... 62 3e-09
U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunction... 52 3e-06
D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase b... 50 1e-05
AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens ... 40 0.007
>D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase precursor protein.
Length = 427
Score = 260 bits (636), Expect = 5e-69
Identities = 128/219 (58%), Positives = 152/219 (69%)
Frame = +3
Query: 69 KVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVC 248
K +L VVI SA TP GSF G AIE+AGIPKEE+KE Y+GNV
Sbjct: 36 KPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVL 95
Query: 249 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 428
GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AGGMES
Sbjct: 96 QGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155
Query: 429 MSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYA 608
MSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I +QD YA
Sbjct: 156 MSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215
Query: 609 VNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 725
+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254
>D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase protein.
Length = 427
Score = 260 bits (636), Expect = 5e-69
Identities = 128/219 (58%), Positives = 152/219 (69%)
Frame = +3
Query: 69 KVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVC 248
K +L VVI SA TP GSF G AIE+AGIPKEE+KE Y+GNV
Sbjct: 36 KPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVL 95
Query: 249 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 428
GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AGGMES
Sbjct: 96 QGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 155
Query: 429 MSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYA 608
MSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I +QD YA
Sbjct: 156 MSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 215
Query: 609 VNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 725
+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 216 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254
>AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA
acetyltransferase, cytosolic variant protein.
Length = 404
Score = 159 bits (385), Expect = 1e-38
Identities = 87/217 (40%), Positives = 120/217 (55%), Gaps = 2/217 (0%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+RS+ + VVI SA T GSF G ++RA + E++ EV
Sbjct: 4 RRSKMNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVI 63
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G+V +A GQ P RQA + AG+P S + +C SG+K++ LA Q + G I++A
Sbjct: 64 FGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVA 123
Query: 414 GGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITX 587
GGME+MS P YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++
Sbjct: 124 GGMENMSKAPHLAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSR 182
Query: 588 QDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 698
+DQD+ AV S R+ A +A F E+VPV V +RG
Sbjct: 183 EDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRG 219
>BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein.
Length = 397
Score = 155 bits (377), Expect = 1e-37
Identities = 85/206 (41%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +3
Query: 87 VVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSANLGQ 266
VVI SA T GSF G ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 267 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 446
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 447 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYAVNSY 620
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++ +DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 621 KRSAAAYEAKAFVDELVPVPVPQKRG 698
R+ A +A F E+VPV V +RG
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRRG 212
>AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A
acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
protein.
Length = 397
Score = 154 bits (374), Expect = 3e-37
Identities = 84/206 (40%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +3
Query: 87 VVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSANLGQ 266
VVI SA T GSF G ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 267 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 446
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 447 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYAVNSY 620
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++ +DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 621 KRSAAAYEAKAFVDELVPVPVPQKRG 698
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA
transferase-like protein protein.
Length = 397
Score = 154 bits (374), Expect = 3e-37
Identities = 84/206 (40%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +3
Query: 87 VVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSANLGQ 266
VVI SA T GSF G ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 267 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 446
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 447 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYAVNSY 620
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++ +DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 621 KRSAAAYEAKAFVDELVPVPVPQKRG 698
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>S70154-1|AAB30856.1| 397|Homo sapiens cytosolic
acetoacetyl-coenzyme A thiolase protein.
Length = 397
Score = 152 bits (368), Expect = 1e-36
Identities = 83/206 (40%), Positives = 114/206 (55%), Gaps = 2/206 (0%)
Frame = +3
Query: 87 VVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSANLGQ 266
VVI SA T GSF G ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 267 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 446
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 447 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYAVNSY 620
YL+ G G M L D I+ DGLTD ++ HMG AEN A K Q++ +DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVATKWQVSREDQDKVAVLSQ 186
Query: 621 KRSAAAYEAKAFVDELVPVPVPQKRG 698
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein.
Length = 162
Score = 124 bits (298), Expect = 4e-28
Identities = 62/110 (56%), Positives = 71/110 (64%)
Frame = +3
Query: 69 KVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVC 248
K +L VVI SA TP GSF G AIE+AGIPKEE+KE Y+GNV
Sbjct: 36 KPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVL 95
Query: 249 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 398
GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G Q
Sbjct: 96 QGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQ 145
>BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein.
Length = 289
Score = 119 bits (287), Expect = 9e-27
Identities = 69/165 (41%), Positives = 95/165 (57%), Gaps = 6/165 (3%)
Frame = +3
Query: 249 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 428
+ LG + A+ AG+PK +V + M +++ +G Q + +L G +
Sbjct: 64 ATKLGSIAIQGAIEKAGIPKE-------EVKEAYMGNVLQGGEG-QAPTRQAVLGAGCDG 115
Query: 429 MS------NVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQ 590
+VP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I
Sbjct: 116 GRWDGEHVHVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 175
Query: 591 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 725
+QD YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 176 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 220
Score = 76.6 bits (180), Expect = 9e-14
Identities = 39/77 (50%), Positives = 44/77 (57%)
Frame = +3
Query: 69 KVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVC 248
K +L VVI SA TP GSF G AIE+AGIPKEE+KE Y+GNV
Sbjct: 36 KPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVL 95
Query: 249 SANLGQAPARQAVIFAG 299
GQAP RQAV+ AG
Sbjct: 96 QGGEGQAPTRQAVLGAG 112
>BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A
acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A
thiolas protein.
Length = 397
Score = 108 bits (260), Expect = 2e-23
Identities = 64/210 (30%), Positives = 105/210 (50%), Gaps = 3/210 (1%)
Frame = +3
Query: 78 LNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSAN 257
L V + +A TP G++ G AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 258 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 434
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 435 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYA 608
P+ ++ R T G ++ ++ LTD + + M AEN A K +I+ ++ D+YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183
Query: 609 VNSYKRSAAAYEAKAFVDELVPVPVPQKRG 698
+ S +R AA +A F DE+ P+ V K+G
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKG 213
>D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-CoA
thiolase protein.
Length = 397
Score = 107 bits (256), Expect = 5e-23
Identities = 63/210 (30%), Positives = 104/210 (49%), Gaps = 3/210 (1%)
Frame = +3
Query: 78 LNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVYIGNVCSAN 257
L V + +A TP G++ G AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 258 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 434
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 435 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYA 608
P+ ++ R T G ++ ++ LTD + + M AEN K +I+ ++ D+YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLTVKHKISREECDKYA 183
Query: 609 VNSYKRSAAAYEAKAFVDELVPVPVPQKRG 698
+ S +R AA +A F DE+ P+ V K+G
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKG 213
>X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA
thiolase protein.
Length = 424
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/165 (29%), Positives = 87/165 (52%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 542
A G++ G+ DI +A G+ESMS RG +L++ + D M
Sbjct: 131 ASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPM 181
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 182 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRNA
for 3-oxoacyl-CoA thiolase. ).
Length = 424
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/165 (29%), Positives = 87/165 (52%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 542
A G++ G+ DI +A G+ESMS RG +L++ + D M
Sbjct: 131 ASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPM 181
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 182 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for
3-oxoacyl-CoA peroxisomal thiolase. ).
Length = 424
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/165 (29%), Positives = 87/165 (52%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 542
A G++ G+ DI +A G+ESMS RG +L++ + D M
Sbjct: 131 ASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPM 181
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 182 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/165 (29%), Positives = 87/165 (52%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 542
A G++ G+ DI +A G+ESMS RG +L++ + D M
Sbjct: 131 ASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPM 181
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 182 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/165 (29%), Positives = 87/165 (52%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 542
A G++ G+ DI +A G+ESMS RG +L++ + D M
Sbjct: 131 ASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPM 181
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 182 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein.
Length = 331
Score = 53.2 bits (122), Expect(2) = 6e-11
Identities = 24/82 (29%), Positives = 48/82 (58%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 71 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 130
Query: 363 MLAAQGLQTGAQDIILAGGMES 428
A G++ G+ DI +A G+ S
Sbjct: 131 ASIAGGIRNGSYDIGMACGITS 152
Score = 33.9 bits (74), Expect(2) = 6e-11
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 543 GNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 677
G +EN A++ I+ + QD +A+ S +++A A F E+VPV
Sbjct: 149 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 193
>BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 44 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 103
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 104 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 163
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLTD---VYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 164 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLASELPAVSEFSTSET 223
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 224 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of trifunctional protein protein.
Length = 474
Score = 63.7 bits (148), Expect = 6e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 43 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 102
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 103 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 162
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 163 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 222
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 223 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 272
>BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 63.7 bits (148), Expect = 6e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 44 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 103
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 104 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 163
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 164 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 223
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 224 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 63.7 bits (148), Expect = 6e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 44 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 103
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 104 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 163
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 164 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 223
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 224 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 63.7 bits (148), Expect = 6e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 44 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 103
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 104 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 163
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 164 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 223
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 224 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 63.7 bits (148), Expect = 6e-10
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 18/231 (7%)
Frame = +3
Query: 54 QRSRPKVSLNAVVIASAVSTPXGSFRGXXXXXXXXXXXXXXXNAAIERAGIPKEEIKEVY 233
+++ K ++ VV+ V TP + R +PKE + +
Sbjct: 43 KKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYII 102
Query: 234 IGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILA 413
G V AR+A + AG T TV C S +++ + +G D+I+A
Sbjct: 103 FGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVA 162
Query: 414 GGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH---- 539
GG+E MS+VP L + ++ + L+ F+ L ++F
Sbjct: 163 GGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSET 222
Query: 540 MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 223 MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 272
>X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase
protein.
Length = 326
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/135 (31%), Positives = 73/135 (54%)
Frame = +3
Query: 273 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 452
AR A + +P++ +TVN+ C+SG++++ A G++ G+ DI +A G+ESMS
Sbjct: 3 ARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LA 58
Query: 453 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITXQDQDEYAVNSYKRSA 632
RG +L++ + D MG +EN A++ I+ + QD +A+ S +++A
Sbjct: 59 DRGNPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAA 113
Query: 633 AAYEAKAFVDELVPV 677
A F E+VPV
Sbjct: 114 RAQSKGCFQAEIVPV 128
>U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunctional
protein beta subunit protein.
Length = 224
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 18/158 (11%)
Frame = +3
Query: 273 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY- 449
AR+A + AG T TV C S +++ A + +G D+++AGG+E MS+VP
Sbjct: 15 AREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRH 74
Query: 450 ----------LKRGETSYGGMQLVDGIVFDGLT-------DVYNKFHMGNCAENTAKKLQ 578
L + +T + L+ + L+ + MG+ A+ A
Sbjct: 75 SRNMRKMMLDLNKAKTLGQRLSLLSKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFA 134
Query: 579 ITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 692
++ +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 135 VSRMEQDEYALRSHSLAKKAQD-EGHLSDIVPFKVPGK 171
>D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of mitochondrial trifunctional protein
protein.
Length = 410
Score = 49.6 bits (113), Expect = 1e-05
Identities = 46/181 (25%), Positives = 82/181 (45%), Gaps = 18/181 (9%)
Frame = +3
Query: 204 IPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 383
+ + + KE G CS ++ A A + AG T TV C S +++ +
Sbjct: 30 VSQTQYKECCGGGWCSHSIF-AVWHFAALGAGFSDKTPAHTVTMACISANQAMTTGVGLI 88
Query: 384 QTGAQDIILAGGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---D 521
+G D+I+AGG+E MS+VP L + ++ + L+ F+ L
Sbjct: 89 ASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELP 148
Query: 522 VYNKFH----MGNCAENTAKKLQITXQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQ 689
++F MG+ A+ A ++ +QDEYA+ S+ + A + + + ++VP VP
Sbjct: 149 AVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPG 207
Query: 690 K 692
K
Sbjct: 208 K 208
>AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens
clone 23623 mRNA, partial cds. ).
Length = 132
Score = 40.3 bits (90), Expect = 0.007
Identities = 16/60 (26%), Positives = 35/60 (58%)
Frame = +3
Query: 183 AAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSI 362
A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++++
Sbjct: 50 AVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAV 109
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,278,036
Number of Sequences: 237096
Number of extensions: 1994614
Number of successful extensions: 7596
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 7421
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7589
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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